Abbas, Kaja M; Dorratoltaj, Nargesalsadat; O'Dell, Margaret L; Bordwine, Paige; Kerkering, Thomas M; Redican, Kerry J; (2015) Clinical Response, Outbreak Investigation, and Epidemiology of the Fungal Meningitis Epidemic in the United States: Systematic Review. Disaster medicine and public health preparedness, 10 (1). pp. 145-151. ISSN 1935-7893 DOI: https://doi.org/10.1017/dmp.2015.137

Afolabi, Muhammed Olanrewaju; McGrath, Nuala; D'Alessandro, Umberto; Kampmann, Beate; Imoukhuede, Egeruan B; Ravinetto, Raffaella M; Alexander, Neal; Larson, Heidi J; Chandramohan, Daniel; Bojang, Kalifa; (2015) A multimedia consent tool for research participants in the Gambia: a randomized controlled trial. Bulletin of the World Health Organization, 93 (5). 320-328A. ISSN 0042-9686 DOI: https://doi.org/10.2471/BLT.14.146159

Agyepong, Irene; Corrah, Tumani; Guo, Yan; Hollingsworth, Bruce; Klag, Michael; Longfield, Kim; de Fatima Marinho de Souza, Maria; Piot, Peter; Rao, JVR Prasada; Røttingen, John-Arne; +6 more... Smith, Peter; Sprenger, Marc; Sutton, Trevor; Curran, Sarah; Ng, Edmond SW; Independent Advisory Committee to the Global Burden of Disease; (2015) Making sense of health estimates. Lancet, 385 (9976). pp. 1377-1379. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(15)60024-1 Full text not available from this repository.

Andrianakis, Ioannis; Vernon, Ian R; McCreesh, Nicky; McKinley, Trevelyan J; Oakley, Jeremy E; Nsubuga, Rebecca N; Goldstein, Michael; White, Richard G; (2015) Bayesian history matching of complex infectious disease models using emulation: a tutorial and a case study on HIV in Uganda. PLoS computational biology, 11 (1). e1003968-. ISSN 1553-734X DOI: https://doi.org/10.1371/journal.pcbi.1003968

Baker, Kate S; Dallman, Timothy J; Ashton, Philip M; Day, Martin; Hughes, Gwenda; Crook, Paul D; Gilbart, Victoria L; Zittermann, Sandra; Allen, Vanessa G; Howden, Benjamin P; +19 more... Tomita, Takehiro; Valcanis, Mary; Harris, Simon R; Connor, Thomas R; Sintchenko, Vitali; Howard, Peter; Brown, Jeremy D; Petty, Nicola K; Gouali, Malika; Thanh, Duy Pham; Keddy, Karen H; Smith, Anthony M; Talukder, Kaisar A; Faruque, Shah M; Parkhill, Julian; Baker, Stephen; Weill, François-Xavier; Jenkins, Claire; Thomson, Nicholas R; (2015) Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study. The Lancet infectious diseases, 15 (8). pp. 913-921. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(15)00002-X Full text not available from this repository.

Bower, Hilary; Grass, Julian E; Veltus, Emily; Brault, Aaron; Campbell, Shelley; Basile, Alison Jane; Wang, David; Paddock, Christopher D; Erickson, Bobbie R; Salzer, Johanna S; +7 more... Belser, Jessica; Chege, Eunice; Seneca, Dean; Saffa, Gbessay; Stroeher, Ute; Decroo, Tom; Caleo, Grazia M; (2015) Delivery of an Ebola Virus-Positive Stillborn Infant in a Rural Community Health Center, Sierra Leone, 2015. The American journal of tropical medicine and hygiene, 94 (2). pp. 417-419. ISSN 0002-9637 DOI: https://doi.org/10.4269/ajtmh.15-0619

Brady, Oliver J; Godfray, H Charles J; Tatem, Andrew J; Gething, Peter W; Cohen, Justin M; McKenzie, F Ellis; Alex Perkins, T; Reiner, Robert C; Tusting, Lucy S; Scott, Thomas W; +3 more... Lindsay, Steven W; Hay, Simon I; Smith, David L; (2015) Adult vector control, mosquito ecology and malaria transmission. Int Health, 7 (2). pp. 121-129. ISSN 1876-3405 DOI: https://doi.org/10.1093/inthealth/ihv010

Camacho, A; Kucharski, A; Aki-Sawyerr, Y; White, MA; Flasche, S; Baguelin, M; Pollington, T; Carney, JR; Glover, R; Smout, E; +3 more... Tiffany, A; Edmunds, WJ; Funk, S; (2015) Temporal changes in ebola transmission in sierra leone and implications for control requirements: A real-time modelling study. PLoS Currents, 7 (OUTBRE). 55052-. DOI: https://doi.org/10.1371/currents.outbreaks.406ae55e83ec0b5193e3085

De Maio, Nicola; Wu, Chieh-Hsi; O'Reilly, Kathleen M; Wilson, Daniel; (2015) New Routes to Phylogeography: A Bayesian Structured Coalescent Approximation. PLoS genetics, 11 (8). e1005421-. ISSN 1553-7390 DOI: https://doi.org/10.1371/journal.pgen.1005421

Dodd, Peter J; Looker, Clare; Plumb, Ian D; Bond, Virginia; Schaap, Ab; Shanaube, Kwame; Muyoyeta, Monde; Vynnycky, Emilia; Godfrey-Faussett, Peter; Corbett, Elizabeth L; +3 more... Beyers, Nulda; Ayles, Helen; White, Richard G; (2015) Age- and Sex-Specific Social Contact Patterns and Incidence of Mycobacterium tuberculosis Infection. American journal of epidemiology, 183 (2). pp. 156-166. ISSN 0002-9262 DOI: https://doi.org/10.1093/aje/kwv160

Eakle, Robyn; Jarrett, Caitlin; Bourne, Adam; Stadler, Jonathan; Larson, Heidi; (2015) Protocol for a systematic review: understanding the motivations and barriers to uptake and use of female-initiated, primary biomedical HIV prevention technologies in sub-Saharan Africa. Systematic reviews, 4 (1). 111-. ISSN 2046-4053 DOI: https://doi.org/10.1186/s13643-015-0096-1

Eggo, Rosalind M; Watson, Conall H; Camacho, Anton; Kucharski, Adam J; Funk, Sebastian; Edmunds, W John; (2015) Duration of Ebola virus RNA persistence in semen of survivors: population-level estimates and projections. Euro surveillance, 20 (48). 30083-. ISSN 1025-496X DOI: https://doi.org/10.2807/1560-7917.ES.2015.20.48.30083

Farooqui, Habib; Jit, Mark; Heymann, David L; Zodpey, Sanjay; (2015) Burden of Severe Pneumonia, Pneumococcal Pneumonia and Pneumonia Deaths in Indian States: Modelling Based Estimates. PloS one, 10 (6). e0129191-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0129191

Glynn, Judith R; Guerra-Assunção, José Afonso; Houben, Rein MGJ; Sichali, Lifted; Mzembe, Themba; Mwaungulu, Lorrain K; Mwaungulu, J Nimrod; McNerney, Ruth; Khan, Palwasha; Parkhill, Julian; +2 more... Crampin, Amelia C; Clark, Taane G; (2015) Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi. PloS one, 10 (7). e0132840-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0132840

Guerra-Assunção, JA; Crampin, AC; Houben, RMGJ; Mzembe, T; Mallard, K; Coll, F; Khan, P; Banda, L; Chiwaya, A; Pereira, RPA; +5 more... McNerney, R; Fine, PEM; Parkhill, J; Clark, TG; Glynn, JR; (2015) Large-scale whole genome sequencing of M. tuberculosis provides insights into transmission in a high prevalence area. eLife, 4 (4). ISSN 2050-084X DOI: https://doi.org/10.7554/eLife.05166

Haque, Farhana; (2015) Outbreaks of Cutaneous Anthrax among Humans in Bangladesh: Understanding the Risk Factors from a Case-Control Analysis. In: ICEID Conference 2015, 2015, Hyatt Regency Hotel, Atlanta, Georgia, USA. DOI: https://doi.org/10.13140/RG.2.2.18002.15045

Harding-Esch, Emma; Nardone, Anthony; Gibbs, Jo; Sutcliffe, Lorna; Sonnenberg, Pam; Estcourt, Claudia; Hughes, Gwenda; Mohammed, Hamish; Gill, Noel; Sadiq, S Tariq; +1 more... Lowndes, Catherine; (2015) Can remote STI/HIV testing and eClinical Care be compatible with robust public health surveillance? DH15 (2015), 2015-M. pp. 129-130. DOI: https://doi.org/10.1145/2750511.2750517

Heesterbeek, Hans; Anderson, Roy M; Andreasen, Viggo; Bansal, Shweta; De Angelis, Daniela; Dye, Chris; Eames, Ken TD; Edmunds, W John; Frost, Simon DW; Funk, Sebastian; +13 more... Hollingsworth, T Deirdre; House, Thomas; Isham, Valerie; Klepac, Petra; Lessler, Justin; Lloyd-Smith, James O; Metcalf, C Jessica E; Mollison, Denis; Pellis, Lorenzo; Pulliam, Juliet RC; Roberts, Mick G; Viboud, Cecile; Isaac Newton Institute IDD Collaboration; (2015) Modeling infectious disease dynamics in the complex landscape of global health. Science (New York, NY), 347 (6227). aaa4339-. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.aaa4339 Full text not available from this repository.

Henderson, Robert A; Jarvis, Christopher; Clayton, Tim; Pocock, Stuart J; Fox, Keith AA; (2015) 10-Year Mortality Outcome of a Routine Invasive Strategy Versus a Selective Invasive Strategy in Non-ST-Segment Elevation Acute Coronary Syndrome: The British Heart Foundation RITA-3 Randomized Trial. Journal of the American College of Cardiology, 66 (5). pp. 511-520. ISSN 0735-1097 DOI: https://doi.org/10.1016/j.jacc.2015.05.051

Hollingsworth, T Déirdre; Adams, Emily R; Anderson, Roy M; Atkins, Katherine; Bartsch, Sarah; Basáñez, María-Gloria; Behrend, Matthew; Blok, David J; Chapman, Lloyd AC; Coffeng, Luc; +36 more... Courtenay, Orin; Crump, Ron E; de Vlas, Sake J; Dobson, Andy; Dyson, Louise; Farkas, Hajnal; Galvani, Alison P; Gambhir, Manoj; Gurarie, David; Irvine, Michael A; Jervis, Sarah; Keeling, Matt J; Kelly-Hope, Louise; King, Charles; Lee, Bruce Y; Le Rutte, Epke A; Lietman, Thomas M; Ndeffo-Mbah, Martial; Medley, Graham F; Michael, Edwin; Pandey, Abhishek; Peterson, Jennifer K; Pinsent, Amy; Porco, Travis C; Richardus, Jan Hendrik; Reimer, Lisa; Rock, Kat S; Singh, Brajendra K; Stolk, Wilma; Swaminathan, Subramanian; Torr, Steve J; Townsend, Jeffrey; Truscott, James; Walker, Martin; Zoueva, Alexandra; NTD Modelling Consortium; (2015) Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases. Parasites & vectors, 8 (1). 630-. ISSN 1756-3305 DOI: https://doi.org/10.1186/s13071-015-1235-1

Jit, Mark; (2015) High-dose influenza vaccines make economic sense for older people. The Lancet infectious diseases, 15 (12). pp. 1372-1373. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(15)00272-8 Full text not available from this repository.

King, EM; Gilson, R; Beddows, S; Soldan, K; Panwar, K; Young, C; Prah, P; Jit, M; Edmunds, WJ; Sonnenberg, P; (2015) Human papillomavirus DNA in men who have sex with men: type-specific prevalence, risk factors and implications for vaccination strategies. British journal of cancer, 112 (9). pp. 1585-1593. ISSN 0007-0920 DOI: https://doi.org/10.1038/bjc.2015.90

King, Eleanor M; Gilson, Richard; Beddows, Simon; Soldan, Kate; Panwar, Kavita; Young, Carmel; Jit, Mark; Edmunds, W John; Sonnenberg, Pam; (2015) Oral human papillomavirus (HPV) infection in men who have sex with men: prevalence and lack of anogenital concordance. Sexually transmitted infections, 91 (4). pp. 284-286. ISSN 1368-4973 DOI: https://doi.org/10.1136/sextrans-2014-051955

Knight, Gwenan M; Dodd, Peter J; Grant, Alison D; Fielding, Katherine L; Churchyard, Gavin J; White, Richard G; (2015) Tuberculosis prevention in South Africa. PloS one, 10 (4). e0122514-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0122514

Knight, Gwenan M; Gomez, Gabriela B; Dodd, Peter J; Dowdy, David; Zwerling, Alice; Wells, William A; Cobelens, Frank; Vassall, Anna; White, Richard G; (2015) The Impact and Cost-Effectiveness of a Four-Month Regimen for First-Line Treatment of Active Tuberculosis in South Africa. PloS one, 10 (12). e0145796-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0145796

Lalli, Marek; Houben, Rein; Churchyard, Gavin; White, Richard G; (2015) Regarding the effect of cured tuberculosis disease on longevity. The international journal of tuberculosis and lung disease, 19 (3). 367-. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.14.0852 Full text not available from this repository.

Larson, Heidi J; Schulz, William S; Tucker, Joseph D; Smith, David MD; (2015) Measuring vaccine confidence: introducing a global vaccine confidence index. PLoS currents, 7 (OUTBRE). ecurrents.outbreaks.ce0f6177bc97332602a8e3fe7d7f7c-. ISSN 2157-3999 DOI: https://doi.org/10.1371/currents.outbreaks.ce0f6177bc97332602a8e3fe7d7f7cc4

Maringe, C; Li, R; Mangtani, P; Coleman, MP; Rachet, B; (2015) Cancer survival differences between South Asians and non-South Asians of England in 1986-2004, accounting for age at diagnosis and deprivation. British journal of cancer, 113 (1). pp. 173-181. ISSN 0007-0920 DOI: https://doi.org/10.1038/bjc.2015.182

McCreesh, N; Faghmous, I; Looker, C; Dodd, PJ; Plumb, ID; Shanaube, K; Muyoyeta, M; Godfrey-Faussett, P; Ayles, H; White, RG; (2015) Coverage of clinic-based TB screening in South Africa may be low in key risk groups. Public health action, 6 (1). pp. 19-21. ISSN 2220-8372 DOI: https://doi.org/10.5588/pha.15.0064

McCreesh, Nicky; Nikulin, Grigory; Booth, Mark; (2015) Predicting the effects of climate change on Schistosoma mansoni transmission in eastern Africa. Parasites & vectors, 8 (1). 4-. ISSN 1756-3305 DOI: https://doi.org/10.1186/s13071-014-0617-0

McQuaid, CF; Sseruwagi, P; Pariyo, A; van den Bosch, F; (2015) Cassava brown streak disease and the sustainability of a clean seed system. Plant pathology, 65 (2). pp. 299-309. ISSN 0032-0862 DOI: https://doi.org/10.1111/ppa.12453

Mourad, Raphaël; Chevennet, François; Dunn, David T; Fearnhill, Esther; Delpech, Valerie; Asboe, David; Gascuel, Olivier; Hue, Stéphane; UK HIV Drug Resistance Database & the Collaborative HIV, Anti-HI; (2015) A phylotype-based analysis highlights the role of drug-naive HIV-positive individuals in the transmission of antiretroviral resistance in the UK. AIDS (London, England), 29 (15). pp. 1917-1925. ISSN 0269-9370 DOI: https://doi.org/10.1097/QAD.0000000000000768 Full text not available from this repository.

Newton, John N; Briggs, Adam DM; Murray, Christopher JL; Dicker, Daniel; Foreman, Kyle J; Wang, Haidong; Naghavi, Mohsen; Forouzanfar, Mohammad H; Ohno, Summer Lockett; Barber, Ryan M; +67 more... Vos, Theo; Stanaway, Jeffrey D; Schmidt, Jürgen C; Hughes, Andrew J; Fay, Derek FJ; Ecob, Russell; Gresser, Charis; McKee, Martin; Rutter, Harry; Abubakar, Ibrahim; Ali, Raghib; Anderson, H Ross; Banerjee, Amitava; Bennett, Derrick A; Bernabé, Eduardo; Bhui, Kamaldeep S; Biryukov, Stanley M; Bourne, Rupert R; Brayne, Carol EG; Bruce, Nigel G; Brugha, Traolach S; Burch, Michael; Capewell, Simon; Casey, Daniel; Chowdhury, Rajiv; Coates, Matthew M; Cooper, Cyrus; Critchley, Julia A; Dargan, Paul I; Dherani, Mukesh K; Elliott, Paul; Ezzati, Majid; Fenton, Kevin A; Fraser, Maya S; Fürst, Thomas; Greaves, Felix; Green, Mark A; Gunnell, David J; Hannigan, Bernadette M; Hay, Roderick J; Hay, Simon I; Hemingway, Harry; Larson, Heidi J; Looker, Katharine J; Lunevicius, Raimundas; Lyons, Ronan A; Marcenes, Wagner; Mason-Jones, Amanda J; Matthews, Fiona E; Moller, Henrik; Murdoch, Michele E; Newton, Charles R; Pearce, Neil; Piel, Frédéric B; Pope, Daniel; Rahimi, Kazem; Rodriguez, Alina; Scarborough, Peter; Schumacher, Austin E; Shiue, Ivy; Smeeth, Liam; Tedstone, Alison; Valabhji, Jonathan; Williams, Hywel C; Wolfe, Charles DA; Woolf, Anthony D; Davis, Adrian CJ; (2015) Changes in health in England, with analysis by English regions and areas of deprivation, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet, 386 (10010). pp. 2257-2274. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(15)00195-6

O'Reilly, KM; Cori, A; Durry, E; Wadood, MZ; Bosan, A; Aylward, RB; Grassly, NC; (2015) A New Method for Estimating the Coverage of Mass Vaccination Campaigns Against Poliomyelitis From Surveillance Data. American journal of epidemiology, 182 (11). pp. 961-970. ISSN 0002-9262 DOI: https://doi.org/10.1093/aje/kwv199

Pan, Xiong-Fei; Griffiths, Ulla K; Pennington, Mark; Yu, Hongjie; Jit, Mark; (2015) Systematic review of economic evaluations of vaccination programs in mainland China: Are they sufficient to inform decision making? Vaccine, 33 (46). pp. 6164-6172. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.09.081

Parker, Edward Pk; Molodecky, Natalie A; Pons-Salort, Margarita; O'Reilly, Kathleen M; Grassly, Nicholas C; (2015) Impact of inactivated poliovirus vaccine on mucosal immunity: implications for the polio eradication endgame. Expert review of vaccines, 14 (8). pp. 1113-1123. ISSN 1476-0584 DOI: https://doi.org/10.1586/14760584.2015.1052800

Penny, Melissa A; Verity, Robert; Bever, Caitlin A; Sauboin, Christophe; Galactionova, Katya; Flasche, Stefan; White, Michael T; Wenger, Edward A; Van de Velde, Nicolas; Pemberton-Ross, Peter; +6 more... Griffin, Jamie T; Smith, Thomas A; Eckhoff, Philip A; Muhib, Farzana; Jit, Mark; Ghani, Azra C; (2015) Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models. Lancet, 387 (10016). pp. 367-375. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(15)00725-4

Punyacharoensin, Narat; Edmunds, William John; De Angelis, Daniela; Delpech, Valerie; Hart, Graham; Elford, Jonathan; Brown, Alison; Gill, Noel; White, Richard G; (2015) Modelling the HIV epidemic among MSM in the United Kingdom: quantifying the contributions to HIV transmission to better inform prevention initiatives. AIDS (London, England), 29 (3). pp. 339-349. ISSN 0269-9370 DOI: https://doi.org/10.1097/QAD.0000000000000525 Full text not available from this repository.

Reid, A; Grant, AD; White, RG; Dye, C; Vynnycky, E; Fielding, K; Churchyard, G; Pillay, Y; (2015) Accelerating progress towards tuberculosis elimination: the need for combination treatment and prevention. The international journal of tuberculosis and lung disease, 19 (1). pp. 5-9. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.14.0078 Full text not available from this repository.

Thorrington, Dominic; Jit, Mark; Eames, Ken; (2015) Targeted vaccination in healthy school children - Can primary school vaccination alone control influenza? Vaccine, 33 (41). pp. 5415-5424. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.08.031 Full text not available from this repository.

Vynnycky, Emilia; Sumner, Tom; Fielding, Katherine L; Lewis, James J; Cox, Andrew P; Hayes, Richard J; Corbett, Elizabeth L; Churchyard, Gavin J; Grant, Alison D; White, Richard G; (2015) Tuberculosis control in South African gold mines: mathematical modeling of a trial of community-wide isoniazid preventive therapy. American journal of epidemiology, 181 (8). pp. 619-632. ISSN 0002-9262 DOI: https://doi.org/10.1093/aje/kwu320

Wilson, Rose J; Paterson, Pauline; Jarrett, Caitlin; Larson, Heidi J; (2015) Understanding factors influencing vaccination acceptance during pregnancy globally: A literature review. Vaccine, 33 (47). pp. 6420-6429. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2015.08.046

Wong, Vanessa K; Baker, Stephen; Pickard, Derek J; Parkhill, Julian; Page, Andrew J; Feasey, Nicholas A; Kingsley, Robert A; Thomson, Nicholas R; Keane, Jacqueline A; Weill, François-Xavier; +64 more... Edwards, David J; Hawkey, Jane; Harris, Simon R; Mather, Alison E; Cain, Amy K; Hadfield, James; Hart, Peter J; Thieu, Nga Tran Vu; Klemm, Elizabeth J; Glinos, Dafni A; Breiman, Robert F; Watson, Conall H; Kariuki, Samuel; Gordon, Melita A; Heyderman, Robert S; Okoro, Chinyere; Jacobs, Jan; Lunguya, Octavie; Edmunds, W John; Msefula, Chisomo; Chabalgoity, Jose A; Kama, Mike; Jenkins, Kylie; Dutta, Shanta; Marks, Florian; Campos, Josefina; Thompson, Corinne; Obaro, Stephen; MacLennan, Calman A; Dolecek, Christiane; Keddy, Karen H; Smith, Anthony M; Parry, Christopher M; Karkey, Abhilasha; Mulholland, E Kim; Campbell, James I; Dongol, Sabina; Basnyat, Buddha; Dufour, Muriel; Bandaranayake, Don; Naseri, Take Toleafoa; Singh, Shalini Pravin; Hatta, Mochammad; Newton, Paul; Onsare, Robert S; Isaia, Lupeoletalalei; Dance, David; Davong, Viengmon; Thwaites, Guy; Wijedoru, Lalith; Crump, John A; De Pinna, Elizabeth; Nair, Satheesh; Nilles, Eric J; Thanh, Duy Pham; Turner, Paul; Soeng, Sona; Valcanis, Mary; Powling, Joan; Dimovski, Karolina; Hogg, Geoff; Farrar, Jeremy; Holt, Kathryn E; Dougan, Gordon; (2015) Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events. Nature genetics, 47 (6). pp. 632-639. ISSN 1061-4036 DOI: https://doi.org/10.1038/ng.3281 Full text not available from this repository.