Berger, CN; Crepin, VF; Roumeliotis, TI; Wright, JC; Carson, D; Pevsner-Fischer, M; Furniss, RCD; Dougan, G; Dori-Bachash, M; Yu, L; +6 more... Clements, A; Collins, JW; Elinav, E; Larrouy-Maumus, GJ; Choudhary, JS; Frankel, G; (2017) Citrobacter rodentium Subverts ATP Flux and Cholesterol Homeostasis in Intestinal Epithelial Cells In Vivo. Cell metabolism, 26 (5). 738-752.e6. ISSN 1550-4131 DOI: https://doi.org/10.1016/j.cmet.2017.09.003

Johnson, R; Byrne, A; Berger, CN; Klemm, E; Crepin, VF; Dougan, G; Frankel, G; (2017) The Type III Secretion System Effector SptP of Salmonella enterica Serovar Typhi. Journal of bacteriology, 199 (4). ISSN 0021-9193 DOI: https://doi.org/10.1128/JB.00647-16

Mullineaux-Sanders, C; Collins, JW; Ruano-Gallego, D; Levy, M; Pevsner-Fischer, M; Glegola-Madejska, IT; Sågfors, AM; Wong, JLC; Elinav, E; Crepin, VF; +1 more... Frankel, G; (2017) Citrobacter rodentium Relies on Commensals for Colonization of the Colonic Mucosa. Cell reports, 21 (12). pp. 3381-3389. ISSN 2211-1247 DOI: https://doi.org/10.1016/j.celrep.2017.11.086

Pearson, JS; Giogha, C; Mühlen, S; Nachbur, U; Pham, CL; Zhang, Y; Hildebrand, JM; Oates, CV; Lung, TW; Ingle, D; +13 more... Dagley, LF; Bankovacki, A; Petrie, EJ; Schroeder, GN; Crepin, VF; Frankel, G; Masters, SL; Vince, J; Murphy, JM; Sunde, M; Webb, AI; Silke, J; Hartland, EL; (2017) EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation. Nature microbiology, 2. p. 16258. ISSN 2058-5276 DOI: https://doi.org/10.1038/nmicrobiol.2016.258

Pearson, JS; Giogha, C; Mühlen, S; Nachbur, U; Pham, CL; Zhang, Y; Hildebrand, JM; Oates, CV; Lung, TW; Ingle, D; +13 more... Dagley, LF; Bankovacki, A; Petrie, EJ; Schroeder, GN; Crepin, VF; Frankel, G; Masters, SL; Vince, J; Murphy, JM; Sunde, M; Webb, AI; Silke, J; Hartland, EL; (2017) Erratum: EspL is a bacterial cysteine protease effector that cleaves RHIM proteins to block necroptosis and inflammation. Nature Research. DOI: https://doi.org/10.1038/nmicrobiol.2017.24 Full text not available from this repository.

Portaliou, AG; Tsolis, KC; Loos, MS; Balabanidou, V; Rayo, J; Tsirigotaki, A; Crepin, VF; Frankel, G; Kalodimos, CG; Karamanou, S; +1 more... Economou, A; (2017) Hierarchical protein targeting and secretion is controlled by an affinity switch in the type III secretion system of enteropathogenic Escherichia coli. The EMBO journal, 36 (23). pp. 3517-3531. ISSN 0261-4189 DOI: https://doi.org/10.15252/embj.201797515 Full text not available from this repository.

Sandu, P; Crepin, VF; Drechsler, H; McAinsh, AD; Frankel, G; Berger, CN; (2017) The Enterohemorrhagic Escherichia coli Effector EspW Triggers Actin Remodeling in a Rac1-Dependent Manner. Infection and immunity, 85 (9). ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00244-17

Ale, A; Crepin, VF; Collins, JW; Constantinou, N; Habibzay, M; Babtie, AC; Frankel, G; Stumpf, MP; (2016) Model of Host-Pathogen Interaction Dynamics Links In Vivo Optical Imaging and Immune Responses. Infection and immunity, 85 (1). ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00606-16

Crepin, VF; Collins, JW; Habibzay, M; Frankel, G; (2016) Citrobacter rodentium mouse model of bacterial infection. Nature Research. DOI: https://doi.org/10.1038/nprot.2016.100 Full text not available from this repository.

Pallett, MA; Crepin, VF; Serafini, N; Habibzay, M; Kotik, O; Sanchez-Garrido, J; Di Santo, JP; Shenoy, AR; Berger, CN; Frankel, G; (2016) Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells. Mucosal immunology, 10 (3). pp. 602-612. ISSN 1933-0219 DOI: https://doi.org/10.1038/mi.2016.77

Crepin, VF; Habibzay, M; Glegola-Madejska, I; Guenot, M; Collins, JW; Frankel, G; (2015) Tir Triggers Expression of CXCL1 in Enterocytes and Neutrophil Recruitment during Citrobacter rodentium Infection. Infection and immunity, 83 (9). pp. 3342-54. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00291-15 Full text not available from this repository.

Collins, JW; Chervaux, C; Raymond, B; Derrien, M; Brazeilles, R; Kosta, A; Chambaud, I; Crepin, VF; Frankel, G; (2014) Fermented dairy products modulate Citrobacter rodentium-induced colonic hyperplasia. The Journal of infectious diseases, 210 (7). pp. 1029-41. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiu205 Full text not available from this repository.

Collins, JW; Keeney, KM; Crepin, VF; Rathinam, VA; Fitzgerald, KA; Finlay, BB; Frankel, G; (2014) Citrobacter rodentium: infection, inflammation and the microbiota. Nature reviews Microbiology, 12 (9). pp. 612-23. ISSN 1740-1526 DOI: https://doi.org/10.1038/nrmicro3315 Full text not available from this repository.

Pearson, JS; Giogha, C; Ong, SY; Kennedy, CL; Kelly, M; Robinson, KS; Lung, TW; Mansell, A; Riedmaier, P; Oates, CV; +15 more... Zaid, A; Mühlen, S; Crepin, VF; Marches, O; Ang, CS; Williamson, NA; O'Reilly, LA; Bankovacki, A; Nachbur, U; Infusini, G; Webb, AI; Silke, J; Strasser, A; Frankel, G; Hartland, EL; (2013) A type III effector antagonizes death receptor signalling during bacterial gut infection. Nature, 501 (7466). pp. 247-51. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature12524 Full text not available from this repository.

Berger, CN; Crepin, VF; Baruch, K; Mousnier, A; Rosenshine, I; Frankel, G; (2012) EspZ of enteropathogenic and enterohemorrhagic Escherichia coli regulates type III secretion system protein translocation. mBio, 3 (5). ISSN 2150-7511 DOI: https://doi.org/10.1128/mBio.00317-12

Wong, AR; Clements, A; Raymond, B; Crepin, VF; Frankel, G; (2012) The interplay between the Escherichia coli Rho guanine nucleotide exchange factor effectors and the mammalian RhoGEF inhibitor EspH. mBio, 3 (1). ISSN 2150-7511 DOI: https://doi.org/10.1128/mBio.00250-11

Wong, AR; Raymond, B; Collins, JW; Crepin, VF; Frankel, G; (2012) The enteropathogenic E. coli effector EspH promotes actin pedestal formation and elongation via WASP-interacting protein (WIP). Cellular microbiology, 14 (7). pp. 1051-70. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2012.01778.x Full text not available from this repository.

Raymond, B; Crepin, VF; Collins, JW; Frankel, G; (2011) The WxxxE effector EspT triggers expression of immune mediators in an Erk/JNK and NF-κB-dependent manner. Cellular microbiology, 13 (12). pp. 1881-93. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2011.01666.x Full text not available from this repository.

Bulgin, R; Raymond, B; Garnett, JA; Frankel, G; Crepin, VF; Berger, CN; Arbeloa, A; (2010) Bacterial guanine nucleotide exchange factors SopE-like and WxxxE effectors. Infection and immunity, 78 (4). pp. 1417-25. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.01250-09 Full text not available from this repository.

Martinez, E; Schroeder, GN; Berger, CN; Lee, SF; Robinson, KS; Badea, L; Simpson, N; Hall, RA; Hartland, EL; Crepin, VF; +1 more... Frankel, G; (2010) Binding to Na(+) /H(+) exchanger regulatory factor 2 (NHERF2) affects trafficking and function of the enteropathogenic Escherichia coli type III secretion system effectors Map, EspI and NleH. Cellular microbiology, 12 (12). pp. 1718-31. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2010.01503.x

Munera, D; Crepin, VF; Marches, O; Frankel, G; (2010) N-terminal type III secretion signal of enteropathogenic Escherichia coli translocator proteins. Journal of bacteriology, 192 (13). pp. 3534-9. ISSN 0021-9193 DOI: https://doi.org/10.1128/JB.00046-10

Bulgin, R; Arbeloa, A; Goulding, D; Dougan, G; Crepin, VF; Raymond, B; Frankel, G; (2009) The T3SS effector EspT defines a new category of invasive enteropathogenic E. coli (EPEC) which form intracellular actin pedestals. PLoS pathogens, 5 (12). e1000683. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1000683

Crepin, VF; Girard, F; Schüller, S; Phillips, AD; Mousnier, A; Frankel, G; (2009) Dissecting the role of the Tir:Nck and Tir:IRTKS/IRSp53 signalling pathways in vivo. Molecular microbiology, 75 (2). pp. 308-23. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2009.06938.x

Girard, F; Crepin, VF; Frankel, G; (2009) Modelling of infection by enteropathogenic Escherichia coli strains in lineages 2 and 4 ex vivo and in vivo by using Citrobacter rodentium expressing TccP. Infection and immunity, 77 (4). pp. 1304-14. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.01351-08 Full text not available from this repository.

Petty, NK; Bulgin, R; Crepin, VF; Cerdeño-Tárraga, AM; Schroeder, GN; Quail, MA; Lennard, N; Corton, C; Barron, A; Clark, L; +5 more... Toribio, AL; Parkhill, J; Dougan, G; Frankel, G; Thomson, NR; (2009) The Citrobacter rodentium genome sequence reveals convergent evolution with human pathogenic Escherichia coli. Journal of bacteriology, 192 (2). pp. 525-38. ISSN 0021-9193 DOI: https://doi.org/10.1128/JB.01144-09

Arbeloa, A; Bulgin, RR; MacKenzie, G; Shaw, RK; Pallen, MJ; Crepin, VF; Berger, CN; Frankel, G; (2008) Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens. Cellular microbiology, 10 (7). pp. 1429-41. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2008.01136.x Full text not available from this repository.

Berger, CN; Crepin, VF; Jepson, MA; Arbeloa, A; Frankel, G; (2008) The mechanisms used by enteropathogenic Escherichia coli to control filopodia dynamics. Cellular microbiology, 11 (2). pp. 309-22. ISSN 1462-5814 DOI: https://doi.org/10.1111/j.1462-5822.2008.01254.x Full text not available from this repository.

Crepin, VF; Martinez, E; Shaw, RK; Frankel, G; Daniell, SJ; (2008) Structural and functional properties of chimeric EspA-FliCi filaments of EPEC. Journal of molecular biology, 378 (1). pp. 243-50. ISSN 0022-2836 DOI: https://doi.org/10.1016/j.jmb.2008.02.042 Full text not available from this repository.

Dennis, A; Kudo, T; Kruidenier, L; Girard, F; Crepin, VF; MacDonald, TT; Frankel, G; Wiles, S; (2008) The p50 subunit of NF-kappaB is critical for in vivo clearance of the noninvasive enteric pathogen Citrobacter rodentium. Infection and immunity, 76 (11). pp. 4978-88. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00736-08 Full text not available from this repository.

Hemrajani, C; Marches, O; Wiles, S; Girard, F; Dennis, A; Dziva, F; Best, A; Phillips, AD; Berger, CN; Mousnier, A; +7 more... Crepin, VF; Kruidenier, L; Woodward, MJ; Stevens, MP; La Ragione, RM; MacDonald, TT; Frankel, G; (2008) Role of NleH, a type III secreted effector from attaching and effacing pathogens, in colonization of the bovine, ovine, and murine gut. Infection and immunity, 76 (11). pp. 4804-13. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.00742-08 Full text not available from this repository.

Singh, MP; Shaw, RK; Knutton, S; Pallen, MJ; Crepin, VF; Frankel, G; (2008) Identification of amino acid residues within the N-terminal domain of EspA that play a role in EspA filament biogenesis and function. Journal of bacteriology, 190 (6). pp. 2221-6. ISSN 0021-9193 DOI: https://doi.org/10.1128/JB.01753-07 Full text not available from this repository.

Dziva, F; Vlisidou, I; Crepin, VF; Wallis, TS; Frankel, G; Stevens, MP; (2007) Vaccination of calves with EspA, a key colonisation factor of Escherichia coli O157:H7, induces antigen-specific humoral responses but does not confer protection against intestinal colonisation. Veterinary microbiology, 123 (1-3). pp. 254-61. ISSN 0378-1135 DOI: https://doi.org/10.1016/j.vetmic.2007.02.016 Full text not available from this repository.

Wiles, S; Crepin, VF; Childs, G; Frankel, G; Kerton, A; (2007) Use of biophotonic imaging as a training aid for administration of substances in laboratory rodents. Laboratory animals, 41 (3). pp. 321-8. ISSN 0023-6772 DOI: https://doi.org/10.1258/002367707781282785 Full text not available from this repository.

Caron, E; Crepin, VF; Simpson, N; Knutton, S; Garmendia, J; Frankel, G; (2006) Subversion of actin dynamics by EPEC and EHEC. Current opinion in microbiology, 9 (1). pp. 40-5. ISSN 1369-5274 DOI: https://doi.org/10.1016/j.mib.2005.12.008 Full text not available from this repository.

Simpson, N; Shaw, R; Crepin, VF; Mundy, R; FitzGerald, AJ; Cummings, N; Straatman-Iwanowska, A; Connerton, I; Knutton, S; Frankel, G; (2006) The enteropathogenic Escherichia coli type III secretion system effector Map binds EBP50/NHERF1: implication for cell signalling and diarrhoea. Molecular microbiology, 60 (2). pp. 349-63. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2006.05109.x Full text not available from this repository.

Crepin, VF; Prasannan, S; Shaw, RK; Wilson, RK; Creasey, E; Abe, CM; Knutton, S; Frankel, G; Matthews, S; (2005) Structural and functional studies of the enteropathogenic Escherichia coli type III needle complex protein EscJ. Molecular microbiology, 55 (6). pp. 1658-70. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2005.04508.x Full text not available from this repository.

Crepin, VF; Shaw, R; Abe, CM; Knutton, S; Frankel, G; (2005) Polarity of enteropathogenic Escherichia coli EspA filament assembly and protein secretion. Journal of bacteriology, 187 (8). pp. 2881-9. ISSN 0021-9193 DOI: https://doi.org/10.1128/JB.187.8.2881-2889.2005 Full text not available from this repository.

Crepin, VF; Shaw, R; Knutton, S; Frankel, G; (2005) Molecular basis of antigenic polymorphism of EspA filaments: development of a peptide display technology. Journal of molecular biology, 350 (1). pp. 42-52. ISSN 0022-2836 DOI: https://doi.org/10.1016/j.jmb.2005.04.060 Full text not available from this repository.

Garmendia, J; Frankel, G; Crepin, VF; (2005) Enteropathogenic and enterohemorrhagic Escherichia coli infections: translocation, translocation, translocation. Infection and immunity, 73 (5). pp. 2573-85. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.73.5.2573-2585.2005 Full text not available from this repository.

Dahan, S; Knutton, S; Shaw, RK; Crepin, VF; Dougan, G; Frankel, G; (2004) Transcriptome of enterohemorrhagic Escherichia coli O157 adhering to eukaryotic plasma membranes. Infection and immunity, 72 (9). pp. 5452-9. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.72.9.5452-5459.2004 Full text not available from this repository.

Prasannan, S; Simpson, P; Wilson, RK; Crepin, VF; Frankel, G; Matthews, S; (2004) (1)H, (13)C, and (15)N resonance assignments of the EscJ protein, a structural component of the Type III secretion system of enteropathogenic E. coli (EPEC). Journal of biomolecular NMR, 30 (3). pp. 387-8. ISSN 0925-2738 DOI: https://doi.org/10.1007/s10858-004-3532-4 Full text not available from this repository.

Crepin, VF; Faulds, CB; Connerton, IF; (2003) Identification of a type-D feruloyl esterase from Neurospora crassa. Applied microbiology and biotechnology, 63 (5). pp. 567-70. ISSN 0175-7598 DOI: https://doi.org/10.1007/s00253-003-1466-5 Full text not available from this repository.

Crepin, VF; Faulds, CB; Connerton, IF; (2003) Functional classification of the microbial feruloyl esterases. Applied microbiology and biotechnology, 63 (6). pp. 647-52. ISSN 0175-7598 DOI: https://doi.org/10.1007/s00253-003-1476-3 Full text not available from this repository.

Crepin, VF; Faulds, CB; Connerton, IF; (2003) Production and characterization of the Talaromyces stipitatus feruloyl esterase FAEC in Pichia pastoris: identification of the nucleophilic serine. Protein expression and purification, 29 (2). pp. 176-84. ISSN 1046-5928 DOI: https://doi.org/10.1016/S1046-5928(03)00050-0 Full text not available from this repository.

Garcia-Conesa, MT; Crepin, VF; Goldson, AJ; Williamson, G; Cummings, NJ; Connerton, IF; Faulds, CB; Kroon, PA; (2003) The feruloyl esterase system of Talaromyces stipitatus: production of three discrete feruloyl esterases, including a novel enzyme, TsFaeC, with a broad substrate specificity. Journal of biotechnology, 108 (3). pp. 227-41. ISSN 0168-1656 DOI: https://doi.org/10.1016/j.jbiotec.2003.12.003 Full text not available from this repository.

Bibbins, M; Crepin, VF; Cummings, NJ; Mizote, T; Baker, K; Mellits, KH; Connerton, IF; (2002) A regulator gene for acetate utilisation from Neurospora crassa. Molecular genetics and genomics, 267 (4). pp. 498-505. ISSN 1617-4615 DOI: https://doi.org/10.1007/s00438-002-0682-5 Full text not available from this repository.

Crepin, VF; Faulds, CB; Connerton, IF; (2002) A non-modular type B feruloyl esterase from Neurospora crassa exhibits concentration-dependent substrate inhibition. The Biochemical journal, 370 (Pt 2). pp. 417-27. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20020917 Full text not available from this repository.