Items where Author is "Alsford, S"
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Article
Alsford, S;
(2014)
Increased Trypanosoma brucei cathepsin-L activity inhibits human serum-mediated trypanolysis.
Microbial cell (Graz, Austria), 1 (8).
pp. 270-272.
ISSN 2311-2638
DOI: https://doi.org/10.15698/mic2014.08.162
Alsford, S;
(2015)
Subverting lysosomal function in Trypanosoma brucei.
Microbial cell (Graz, Austria), 2 (8).
pp. 259-261.
ISSN 2311-2638
DOI: https://doi.org/10.15698/mic2015.08.222
Alsford, S;
Currier, RB;
Guerra-Assunção, JA;
Clark, TG;
Horn, D;
(2014)
Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei.
PLoS pathogens, 10 (5).
e1004130.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1004130
Alsford, S;
Eckert, S;
Baker, N;
Glover, L;
Sanchez-Flores, A;
Leung, KF;
Turner, DJ;
Field, MC;
Berriman, M;
Horn, D;
(2012)
High-throughput decoding of antitrypanosomal drug efficacy and resistance.
Nature, 482 (7384).
pp. 232-6.
ISSN 0028-0836
DOI: https://doi.org/10.1038/nature10771
Alsford, S;
Horn, D;
(2012)
Cell-cycle-regulated control of VSG expression site silencing by histones and histone chaperones ASF1A and CAF-1b in Trypanosoma brucei.
Nucleic acids research, 40 (20).
pp. 10150-60.
ISSN 0305-1048
DOI: https://doi.org/10.1093/nar/gks813
Currier, RB;
Cooper, A;
Burrell-Saward, H;
MacLeod, A;
Alsford, S;
(2018)
Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.
PLoS pathogens, 14 (1).
e1006855.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1006855
Glover, L;
Alsford, S;
Baker, N;
Turner, DJ;
Sanchez-Flores, A;
Hutchinson, S;
Hertz-Fowler, C;
Berriman, M;
Horn, D;
(2014)
Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes.
Nature protocols, 10 (1).
pp. 106-133.
ISSN 1754-2189
DOI: https://doi.org/10.1038/nprot.2015.005
Full text not available from this repository.
Glover, L;
Alsford, S;
Beattie, C;
Horn, D;
(2007)
Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest.
Nucleic acids research, 35 (3).
pp. 872-80.
ISSN 0305-1048
DOI: https://doi.org/10.1093/nar/gkl1100
Glover, L;
Hutchinson, S;
Alsford, S;
Horn, D;
(2016)
VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1600344113
Glover, L;
Hutchinson, S;
Alsford, S;
McCulloch, R;
Field, MC;
Horn, D;
(2013)
Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control.
Cellular microbiology, 15 (12).
pp. 1984-93.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12215
Full text not available from this repository.
Kawahara, T;
Siegel, TN;
Ingram, AK;
Alsford, S;
Cross, GA;
Horn, D;
(2008)
Two essential MYST-family proteins display distinct roles in histone H4K10 acetylation and telomeric silencing in trypanosomes.
Molecular microbiology, 69 (4).
pp. 1054-68.
ISSN 0950-382X
DOI: https://doi.org/10.1111/j.1365-2958.2008.06346.x
Macedo, JP;
Currier, RB;
Wirdnam, C;
Horn, D;
Alsford, S;
Rentsch, D;
(2017)
Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei.
FASEB journal.
ISSN 0892-6638
DOI: https://doi.org/10.1096/fj.201700311R
Maishman, L;
Obado, SO;
Alsford, S;
Bart, JM;
Chen, WM;
Ratushny, AV;
Navarro, M;
Horn, D;
Aitchison, JD;
Chait, BT;
+2 more...
Rout, MP;
Field, MC;
(2016)
Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.
Nucleic acids research.
ISSN 0305-1048
DOI: https://doi.org/10.1093/nar/gkw751
Meredith, EL;
Kumar, A;
Konno, A;
Szular, J;
Alsford, S;
Seifert, K;
Horn, D;
Wilkinson, SR;
(2017)
Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs.
Molecular microbiology.
ISSN 0950-382X
DOI: https://doi.org/10.1111/mmi.13767
Stortz, JA;
Serafim, TD;
Alsford, S;
Wilkes, J;
Fernandez-Cortes, F;
Hamilton, G;
Briggs, E;
Lemgruber, L;
Horn, D;
Mottram, JC;
+1 more...
McCulloch, R;
(2017)
Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.
PLoS pathogens, 13 (7).
e1006477.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1006477
Zoltner, M;
Leung, KF;
Alsford, S;
Horn, D;
Field, MC;
(2015)
Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes.
PLoS pathogens, 11 (10).
e1005236.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1005236