Subverting lysosomal function in Trypanosoma brucei


Alsford, S; (2015) Subverting lysosomal function in Trypanosoma brucei. Microbial cell (Graz, Austria), 2 (8). pp. 259-261. ISSN 2311-2638 DOI: https://doi.org/10.15698/mic2015.08.222

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Abstract

In this issue of Microbial Cell, Koh and colleagues present data highlighting the utility of the lysosomotropic compound L-leucyl-L-leucyl methyl ester (LeuLeu-OMe) as an anti-Trypanosoma brucei agent, adding to the range of compounds that either directly target lysosomal enzymes or that can be used to subvert the function of the lysosome for parasite destruction.

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
URI: http://researchonline.lshtm.ac.uk/id/eprint/2551528

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