Items where Author is "Whittaker, J"
Up a level |
Number of items: 153.
2016
Charoen, P;
Nitsch, D;
Engmann, J;
Shah, T;
White, J;
Zabaneh, D;
Jefferis, B;
Wannamethee, G;
Whincup, P;
Mulick Cassidy, A;
+31 more...
Gaunt, T;
Day, I;
McLachlan, S;
Price, J;
Kumari, M;
Kivimaki, M;
Brunner, E;
Langenberg, C;
Ben-Shlomo, Y;
Hingorani, A;
Whittaker, J;
Pablo Casas, J;
Dudbridge, F;
UCLEB Consortium;
, COLLABORATORS;
Dale, C;
Finan, C;
Wong, A;
Ong, K;
Drenos, F;
Cooper, J;
Sofat, R;
Schmidt, F;
Lawlor, DA;
Talmud, PJ;
Humphries, SE;
Hardy, R;
Kuh, D;
Wareham, N;
Morris, R;
Plagno, V;
(2016)
Mendelian Randomisation study of the influence of eGFR on coronary heart disease.
Scientific reports, 6.
p. 28514.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep28514
Swerdlow, DI;
Kuchenbaecker, KB;
Shah, S;
Sofat, R;
Holmes, MV;
White, J;
Mindell, JS;
Kivimaki, M;
Brunner, EJ;
Whittaker, JC;
+2 more...
Casas, JP;
Hingorani, AD;
(2016)
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.
International journal of epidemiology.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyw088
2015
Moore, GE;
Ishida, M;
Demetriou, C;
Al-Olabi, L;
Leon, LJ;
Thomas, AC;
Abu-Amero, S;
Frost, JM;
Stafford, JL;
Chaoqun, Y;
+12 more...
Duncan, AJ;
Baigel, R;
Brimioulle, M;
Iglesias-Platas, I;
Apostolidou, S;
Aggarwal, R;
Whittaker, JC;
Syngelaki, A;
Nicolaides, KH;
Regan, L;
Monk, D;
Stanier, P;
(2015)
The role and interaction of imprinted genes in human fetal growth.
Philosophical transactions of the Royal Society of London Series B, Biological sciences, 370 (1663).
ISSN 0962-8436
DOI: https://doi.org/10.1098/rstb.2014.0074
Nelson, MR;
Tipney, H;
Painter, JL;
Shen, J;
Nicoletti, P;
Shen, Y;
Floratos, A;
Sham, PC;
Li, MJ;
Wang, J;
+3 more...
Cardon, LR;
Whittaker, JC;
Sanseau, P;
(2015)
The support of human genetic evidence for approved drug indications.
Nature genetics, 47 (8).
pp. 856-60.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng.3314
Full text not available from this repository.
Nüesch, E;
Dale, C;
Palmer, TM;
White, J;
Keating, BJ;
van Iperen, EP;
Goel, A;
Padmanabhan, S;
Asselbergs, FW;
EPIC-Netherland Investigators;
+71 more...
Verschuren, WM;
Wijmenga, C;
Van der Schouw, YT;
Onland-Moret, NC;
Lange, LA;
Hovingh, GK;
Sivapalaratnam, S;
Morris, RW;
Whincup, PH;
Wannamethe, GS;
Gaunt, TR;
Ebrahim, S;
Steel, L;
Nair, N;
Reiner, AP;
Kooperberg, C;
Wilson, JF;
Bolton, JL;
McLachlan, S;
Price, JF;
Strachan, MW;
Robertson, CM;
Kleber, ME;
Delgado, G;
März, W;
Melander, O;
Dominiczak, AF;
Farrall, M;
Watkins, H;
Leusink, M;
Maitland-van der Zee, AH;
de Groot, MC;
Dudbridge, F;
Hingorani, A;
Ben-Shlomo, Y;
Lawlor, DA;
UCLEB Investigators;
Amuzu, A;
Caufield, M;
Cavadino, A;
Cooper, J;
Davies, TL;
IN Day;
Drenos, F;
Engmann, J;
Finan, C;
Giambartolomei, C;
Hardy, R;
Humphries, SE;
Hypponen, E;
Kivimaki, M;
Kuh, D;
Kumari, M;
Ong, K;
Plagnol, V;
Power, C;
Richards, M;
Shah, S;
Shah, T;
Sofat, R;
Talmud, PJ;
Wareham, N;
Warren, H;
Whittaker, JC;
Wong, A;
Zabaneh, D;
Davey Smith, G;
Wells, JC;
Leon, DA;
Holmes, MV;
Casas, JP;
(2015)
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
International journal of epidemiology.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyv074
Xu, CF;
Johnson, T;
Garcia-Donas, J;
Choueiri, TK;
Sternberg, CN;
Davis, ID;
Bing, N;
Deen, KC;
Xue, Z;
McCann, L;
+6 more...
Esteban, E;
Whittaker, JC;
Spraggs, CF;
Rodríguez-Antona, C;
Pandite, LN;
Motzer, RJ;
(2015)
IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.
British journal of cancer, 112 (7).
pp. 1190-8.
ISSN 0007-0920
DOI: https://doi.org/10.1038/bjc.2015.64
2014
Futema, M;
Shah, S;
Cooper, JA;
Li, K;
Whittall, RA;
Sharifi, M;
Goldberg, O;
Drogari, E;
Mollaki, V;
Wiegman, A;
+16 more...
Defesche, J;
D'Agostino, MN;
D'Angelo, A;
Rubba, P;
Fortunato, G;
Walus-Miarka, M;
Hegele, RA;
Aderayo Bamimore, M;
Durst, R;
Leitersdorf, E;
Mulder, MT;
Roeters van Lennep, JE;
Sijbrands, EJ;
Whittaker, JC;
Talmud, PJ;
Humphries, SE;
(2014)
Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis of the Polygenic Form of Clinical Familial Hypercholesterolemia and Replication in Samples from 6 Countries.
Clinical chemistry.
ISSN 0009-9147
DOI: https://doi.org/10.1373/clinchem.2014.231365
Full text not available from this repository.
Holmes, MV;
Dale, CE;
Zuccolo, L;
Silverwood, RJ;
Guo, Y;
Ye, Z;
Prieto-Merino, D;
Dehghan, A;
Trompet, S;
Wong, A;
+146 more...
Cavadino, A;
Drogan, D;
Padmanabhan, S;
Li, S;
Yesupriya, A;
Leusink, M;
Sundstrom, J;
Hubacek, JA;
Pikhart, H;
Swerdlow, DI;
Panayiotou, AG;
Borinskaya, SA;
Finan, C;
Shah, S;
Kuchenbaecker, KB;
Shah, T;
Engmann, J;
Folkersen, L;
Eriksson, P;
Ricceri, F;
Melander, O;
Sacerdote, C;
Gamble, DM;
Rayaprolu, S;
Ross, OA;
McLachlan, S;
Vikhireva, O;
Sluijs, I;
Scott, RA;
Adamkova, V;
Flicker, L;
Bockxmeer, FM;
Power, C;
Marques-Vidal, P;
Meade, T;
Marmot, MG;
Ferro, JM;
Paulos-Pinheiro, S;
Humphries, SE;
Talmud, PJ;
Mateo Leach, I;
Verweij, N;
Linneberg, A;
Skaaby, T;
Doevendans, PA;
Cramer, MJ;
Harst, Pv;
Klungel, OH;
Dowling, NF;
Dominiczak, AF;
Kumari, M;
Nicolaides, AN;
Weikert, C;
Boeing, H;
Ebrahim, S;
Gaunt, TR;
Price, JF;
Lannfelt, L;
Peasey, A;
Kubinova, R;
Pajak, A;
Malyutina, S;
Voevoda, MI;
Tamosiunas, A;
Maitland-van der Zee, AH;
Norman, PE;
Hankey, GJ;
Bergmann, MM;
Hofman, A;
Franco, OH;
Cooper, J;
Palmen, J;
Spiering, W;
Jong, PA;
Kuh, D;
Hardy, R;
Uitterlinden, AG;
Ikram, MA;
Ford, I;
Hyppönen, E;
Almeida, OP;
Wareham, NJ;
Khaw, KT;
Hamsten, A;
Husemoen, LL;
Tjønneland, A;
Tolstrup, JS;
Rimm, E;
Beulens, JW;
Verschuren, WM;
Onland-Moret, NC;
Hofker, MH;
Wannamethee, SG;
Whincup, PH;
Morris, R;
Vicente, AM;
Watkins, H;
Farrall, M;
Jukema, JW;
Meschia, J;
Cupples, LA;
Sharp, SJ;
Fornage, M;
Kooperberg, C;
LaCroix, AZ;
Dai, JY;
Lanktree, MB;
Siscovick, DS;
Jorgenson, E;
Spring, B;
Coresh, J;
Li, YR;
Buxbaum, SG;
Schreiner, PJ;
Ellison, RC;
Tsai, MY;
Patel, SR;
Redline, S;
Johnson, AD;
Hoogeveen, RC;
Hakonarson, H;
Rotter, JI;
Boerwinkle, E;
Bakker, PI;
Kivimaki, M;
Asselbergs, FW;
Sattar, N;
Lawlor, DA;
Whittaker, J;
Davey Smith, G;
Mukamal, K;
Psaty, BM;
Wilson, JG;
Lange, LA;
Hamidovic, A;
Hingorani, AD;
Nordestgaard, BG;
Bobak, M;
Leon, DA;
Langenberg, C;
Palmer, TM;
Reiner, AP;
Keating, BJ;
Dudbridge, F;
Casas, JP;
InterAct Consortium;
(2014)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
BMJ (Clinical research ed), 349.
g4164.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.g4164
Silverwood, RJ;
Holmes, MV;
Dale, CE;
Lawlor, DA;
Whittaker, JC;
Smith, GD;
Leon, DA;
Palmer, T;
Keating, BJ;
Zuccolo, L;
+3 more...
Casas, JP;
Dudbridge, F;
Alcohol-ADH1B Consortium;
(2014)
Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.
International journal of epidemiology, 43 (6).
pp. 1781-90.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyu187
Swerdlow, DI;
Preiss, D;
Kuchenbaecker, KB;
Holmes, MV;
Engmann, JE;
Shah, T;
Sofat, R;
Stender, S;
Johnson, PC;
Scott, RA;
+126 more...
Leusink, M;
Verweij, N;
Sharp, SJ;
Guo, Y;
Giambartolomei, C;
Chung, C;
Peasey, A;
Amuzu, A;
Li, K;
Palmen, J;
Howard, P;
Cooper, JA;
Drenos, F;
Li, YR;
Lowe, G;
Gallacher, J;
Stewart, MC;
Tzoulaki, I;
Buxbaum, SG;
van der A, DL;
Forouhi, NG;
Onland-Moret, NC;
van der Schouw, YT;
Schnabel, RB;
Hubacek, JA;
Kubinova, R;
Baceviciene, M;
Tamosiunas, A;
Pajak, A;
Topor-Madry, R;
Stepaniak, U;
Malyutina, S;
Baldassarre, D;
Sennblad, B;
Tremoli, E;
de Faire, U;
Veglia, F;
Ford, I;
Jukema, JW;
Westendorp, RG;
de Borst, GJ;
de Jong, PA;
Algra, A;
Spiering, W;
Maitland-van der Zee, AH;
Klungel, OH;
de Boer, A;
Doevendans, PA;
Eaton, CB;
Robinson, JG;
Duggan, D;
DIAGRAM Consortium;
MAGIC Consortium;
InterAct Consortium;
Kjekshus, J;
Downs, JR;
Gotto, AM;
Keech, AC;
Marchioli, R;
Tognoni, G;
Sever, PS;
Poulter, NR;
Waters, DD;
Pedersen, TR;
Amarenco, P;
Nakamura, H;
McMurray, JJ;
Lewsey, JD;
Chasman, DI;
Ridker, PM;
Maggioni, AP;
Tavazzi, L;
Ray, KK;
Seshasai, SR;
Manson, JE;
Price, JF;
Whincup, PH;
Morris, RW;
Lawlor, DA;
Smith, GD;
Ben-Shlomo, Y;
Schreiner, PJ;
Fornage, M;
Siscovick, DS;
Cushman, M;
Kumari, M;
Wareham, NJ;
Verschuren, WM;
Redline, S;
Patel, SR;
Whittaker, JC;
Hamsten, A;
Delaney, JA;
Dale, C;
Gaunt, TR;
Wong, A;
Kuh, D;
Hardy, R;
Kathiresan, S;
Castillo, BA;
van der Harst, P;
Brunner, EJ;
Tybjaerg-Hansen, A;
Marmot, MG;
Krauss, RM;
Tsai, M;
Coresh, J;
Hoogeveen, RC;
Psaty, BM;
Lange, LA;
Hakonarson, H;
Dudbridge, F;
Humphries, SE;
Talmud, PJ;
Kivimäki, M;
Timpson, NJ;
Langenberg, C;
Asselbergs, FW;
Voevoda, M;
Bobak, M;
Pikhart, H;
Wilson, JG;
Reiner, AP;
Keating, BJ;
Hingorani, AD;
Sattar, N;
(2014)
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Lancet, 385 (9965).
pp. 351-61.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(14)61183-1
Talmud, PJ;
Cooper, JA;
Morris, RW;
Dudbridge, F;
Shah, T;
Engmann, J;
Dale, C;
White, J;
McLachlan, S;
Zabaneh, D;
+21 more...
Wong, A;
Ong, KK;
Gaunt, T;
Holmes, MV;
Lawlor, DA;
Richards, M;
Hardy, R;
Kuh, D;
Wareham, N;
Langenberg, C;
Ben-Shlomo, Y;
Wannamethee, SG;
Strachan, MW;
Kumari, M;
Whittaker, JC;
Drenos, F;
Kivimaki, M;
Hingorani, AD;
Price, JF;
Humphries, SE;
on behalf of the UCLEB Consortium;
(2014)
Sixty-five common genetic variants and prediction of type 2 diabetes.
Diabetes.
ISSN 0012-1797
DOI: https://doi.org/10.2337/db14-1504
Vimaleswaran, KS;
Cavadino, A;
Berry, DJ;
LifeLines Cohort Study investigators;
Jorde, R;
Dieffenbach, AK;
Lu, C;
Alves, AC;
Heerspink, HJ;
Tikkanen, E;
+98 more...
Eriksson, J;
Wong, A;
Mangino, M;
Jablonski, KA;
Nolte, IM;
Houston, DK;
Ahluwalia, TS;
van der Most, PJ;
Pasko, D;
Zgaga, L;
Thiering, E;
Vitart, V;
Fraser, RM;
Huffman, JE;
de Boer, RA;
Schöttker, B;
Saum, KU;
McCarthy, MI;
Dupuis, J;
Herzig, KH;
Sebert, S;
Pouta, A;
Laitinen, J;
Kleber, ME;
Navis, G;
Lorentzon, M;
Jameson, K;
Arden, N;
Cooper, JA;
Acharya, J;
Hardy, R;
Raitakari, O;
Ripatti, S;
Billings, LK;
Lahti, J;
Osmond, C;
Penninx, BW;
Rejnmark, L;
Lohman, KK;
Paternoster, L;
Stolk, RP;
Hernandez, DG;
Byberg, L;
Hagström, E;
Melhus, H;
Ingelsson, E;
Mellström, D;
Ljunggren, O;
Tzoulaki, I;
McLachlan, S;
Theodoratou, E;
Tiesler, CM;
Jula, A;
Navarro, P;
Wright, AF;
Polasek, O;
International Consortium for Blood Pressure (ICBP);
Cohorts for Heart and Aging Research in Genomic Epidemiology (CH;
Global Blood Pressure Genetics (Global BPGen) consortium;
Caroline Hayward;
Wilson, JF;
Rudan, I;
Salomaa, V;
Heinrich, J;
Campbell, H;
Price, JF;
Karlsson, M;
Lind, L;
Michaëlsson, K;
Bandinelli, S;
Frayling, TM;
Hartman, CA;
Sørensen, TI;
Kritchevsky, SB;
Langdahl, BL;
Eriksson, JG;
Florez, JC;
Spector, TD;
Lehtimäki, T;
Kuh, D;
Humphries, SE;
Cooper, C;
Ohlsson, C;
März, W;
de Borst, MH;
Kumari, M;
Kivimaki, M;
Wang, TJ;
Power, C;
Brenner, H;
Grimnes, G;
van der Harst, P;
Snieder, H;
Hingorani, AD;
Pilz, S;
Whittaker, JC;
Järvelin, MR;
Hyppönen, E;
(2014)
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
The lancet Diabetes & endocrinology.
ISSN 2213-8587
DOI: https://doi.org/10.1016/S2213-8587(14)70113-5
2013
Chan, K;
Patel, RS;
Newcombe, P;
Nelson, CP;
Qasim, A;
Epstein, SE;
Burnett, S;
Vaccarino, VL;
Zafari, AM;
Shah, SH;
+42 more...
Anderson, JL;
Carlquist, JF;
Hartiala, J;
Allayee, H;
Hinohara, K;
Lee, BS;
Erl, A;
Ellis, KL;
Goel, A;
Schaefer, AS;
el Mokhtari, NE;
Goldstein, BA;
Hlatky, MA;
Go, AS;
Shen, GQ;
Gong, Y;
Pepine, C;
Laxton, RC;
Whittaker, JC;
Tang, WHW;
Johnson, JA;
Wang, QK;
Assimes, TL;
Nothlings, U;
Farrall, M;
Watkins, H;
Richards, AM;
Cameron, VA;
Muendlein, A;
Drexel, H;
Koch, W;
Park, JE;
Kimura, A;
Shen, WF;
Simpson, IA;
Hazen, SL;
Horne, BD;
Hauser, ER;
Quyyumi, AA;
Reilly, MP;
Samani, NJ;
Ye, S;
(2013)
Association Between the Chromosome 9p21 Locus and Angiographic Coronary Artery Disease Burden A Collaborative Meta-Analysis.
Journal of the American College of Cardiology, 61 (9).
pp. 957-970.
ISSN 0735-1097
DOI: https://doi.org/10.1016/j.jacc.2012.10.051
Full text not available from this repository.
Dixon, PH;
Wadsworth, CA;
Chambers, J;
Donnelly, J;
Cooley, S;
Buckley, R;
Mannino, R;
Jarvis, S;
Syngelaki, A;
Geenes, V;
+13 more...
Paul, P;
Sothinathan, M;
Kubitz, R;
Lammert, F;
Tribe, RM;
Ch'ng, CL;
Marschall, HU;
Glantz, A;
Khan, SA;
Nicolaides, K;
Whittaker, J;
Geary, M;
Williamson, C;
(2013)
A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy.
The American journal of gastroenterology, 109 (1).
pp. 76-84.
ISSN 0002-9270
DOI: https://doi.org/10.1038/ajg.2013.406
Full text not available from this repository.
Hu, Y;
Li, L;
Ehm, MG;
Bing, N;
Song, K;
Nelson, MR;
Talmud, PJ;
Hingorani, AD;
Kumari, M;
Kivimäki, M;
+6 more...
Xu, CF;
Waterworth, DM;
Whittaker, JC;
Abecasis, GR;
Spino, C;
Kang, HM;
(2013)
The benefits of using genetic information to design prevention trials.
American journal of human genetics, 92 (4).
pp. 547-57.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2013.03.003
Full text not available from this repository.
Khan, TA;
Shah, T;
Prieto, D;
Zhang, W;
Price, J;
Fowkes, GR;
Cooper, J;
Talmud, PJ;
Humphries, SE;
Sundstrom, J;
+39 more...
Hubacek, JA;
Ebrahim, S;
Lawlor, DA;
Ben-Shlomo, Y;
Abdollahi, MR;
Slooter, AJ;
Szolnoki, Z;
Sandhu, M;
Wareham, N;
Frikke-Schmidt, R;
Tybjærg-Hansen, A;
Fillenbaum, G;
Heijmans, BT;
Katsuya, T;
Gromadzka, G;
Singleton, A;
Ferrucci, L;
Hardy, J;
Worrall, B;
Rich, SS;
Matarin, M;
Whittaker, J;
Gaunt, TR;
Whincup, P;
Morris, R;
Deanfield, J;
Donald, A;
Davey Smith, G;
Kivimaki, M;
Kumari, M;
Smeeth, L;
Khaw, KT;
Nalls, M;
Meschia, J;
Sun, K;
Hui, R;
Day, I;
Hingorani, AD;
Casas, JP;
(2013)
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals.
International journal of epidemiology, 42 (2).
pp. 475-492.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyt034
Full text not available from this repository.
Mann, AG;
Mangtani, P;
Russell, CA;
Whittaker, JC;
(2013)
The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study.
BMJ open, 3 (8).
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2013-002743
Shah, S;
Casas, JP;
Drenos, F;
Whittaker, J;
Deanfield, J;
Swerdlow, DI;
Holmes, MV;
Kivimaki, M;
Langenberg, C;
Wareham, N;
+13 more...
Gertow, K;
Sennblad, B;
Strawbridge, RJ;
Baldassarre, D;
Veglia, F;
Tremoli, E;
Gigante, B;
de Faire, U;
Kumari, M;
Talmud, PJ;
Hamsten, A;
Humphries, SE;
Hingorani, AD;
(2013)
Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis Mendelian Randomization Analysis.
Circulation Cardiovascular genetics, 6 (1).
pp. 63-72.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.112.963140
Full text not available from this repository.
Shah, T;
Engmann, J;
Dale, C;
Shah, S;
White, J;
Giambartolomei, C;
McLachlan, S;
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Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype.
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Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations.
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Comparative analysis of genome-wide-association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
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Comparison of methods and sampling designs to test for association between rare variants and quantitative traits.
Genetic epidemiology.
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Balchin, I;
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Maternal and Fetal Characteristics Associated With Meconium-Stained Amniotic Fluid.
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Application of the Lasso to Expression Quantitative Trait Loci Mapping.
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Kaptoge, S;
Di Angelantonio, E;
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Nordestgaard, BG;
Saleheen, D;
Samani, NJ;
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Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.
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Performance of genotype imputation for rare variants identified in exons and flanking regions of genes.
PloS one, 6 (9).
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DOI: https://doi.org/10.1371/journal.pone.0024945
Shah, S;
Nelson, CP;
Gaunt, TR;
van der Harst, P;
Barnes, T;
Braund, PS;
Lawlor, DA;
Casas, JP;
Padmanabhan, S;
Drenos, F;
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Kivimaki, M;
Talmud, PJ;
Humphries, SE;
Whittaker, J;
Morris, RW;
Whincup, PH;
Dominiczak, A;
Munroe, PB;
Johnson, T;
Goodall, AH;
Cambien, F;
Diemert, P;
Hengstenberg, C;
Ouwehand, WH;
Felix, JF;
Glazer, NL;
Tomaszewski, M;
Burton, PR;
Tobin, MD;
van Veldhuisen, DJ;
de Boer, RA;
Navis, G;
van Gilst, WH;
Mayosi, BM;
Thompson, JR;
Kumari, M;
MacFarlane, PW;
Day, IN;
Hingorani, AD;
Samani, NJ;
(2011)
Four Genetic Loci Influencing Electrocardiographic Indices of Left Ventricular Hypertrophy.
Circulation Cardiovascular genetics, 4 (6).
pp. 626-35.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.111.960203
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Spraggs, CF;
Budde, LR;
Briley, LP;
Bing, N;
Cox, CJ;
King, KS;
Whittaker, JC;
Mooser, VE;
Preston, AJ;
Stein, SH;
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Cardon, LR;
(2011)
HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer.
Journal of clinical oncology, 29 (6).
pp. 667-73.
ISSN 0732-183X
DOI: https://doi.org/10.1200/JCO.2010.31.3197
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Talmud, PJ;
Cooper, JA;
Gaunt, T;
Holmes, MV;
Shah, S;
Palmen, J;
Drenos, F;
Shah, T;
Kumari, M;
Kivimaki, M;
+6 more...
Whittaker, J;
Lawlor, DA;
Day, IN;
Hingorani, AD;
Casas, JP;
Humphries, SE;
(2011)
Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.
Diabetologia, 54 (7).
pp. 1710-1719.
ISSN 0012-186X
DOI: https://doi.org/10.1007/s00125-011-2108-6
Wadsworth, CA;
Dixon, PH;
Wong, JH;
Chapman, MH;
McKay, SC;
Sharif, A;
Spalding, DR;
Pereira, SP;
Thomas, HC;
Taylor-Robinson, SD;
+3 more...
Whittaker, J;
Williamson, C;
Khan, SA;
(2011)
Genetic Factors in the Pathogenesis of Cholangiocarcinoma.
Digestive diseases (Basel, Switzerland), 29 (1).
pp. 93-97.
ISSN 0257-2753
DOI: https://doi.org/10.1159/000324688
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Xu, CF;
Bing, NX;
Ball, HA;
Rajagopalan, D;
Sternberg, CN;
Hutson, TE;
de Souza, P;
Xue, ZG;
McCann, L;
King, KS;
+6 more...
Ragone, LJ;
Whittaker, JC;
Spraggs, CF;
Cardon, LR;
Mooser, VE;
Pandite, LN;
(2011)
Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes.
Journal of clinical oncology, 29 (18).
pp. 2557-64.
ISSN 0732-183X
DOI: https://doi.org/10.1200/JCO.2010.32.9110
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Zabaneh, D;
Gaunt, TR;
Kumari, M;
Drenos, F;
Shah, S;
Berry, D;
Power, C;
Hypponen, E;
Shah, T;
Palmen, J;
+18 more...
Pallas, J;
Talmud, PJ;
Casas, JP;
Sofat, R;
Lowe, G;
Rumley, A;
Morris, RW;
Whincup, PH;
Rodriguez, S;
Ebrahim, S;
Marmot, MG;
Smith, GD;
Lawlor, DA;
Kivimaki, M;
Whittaker, J;
Hingorani, AD;
Day, IN;
Humphries, SE;
(2011)
Genetic Variants Associated with von Willebrand Factor Levels in Healthy Men and Women Identified Using the HumanCVD BeadChip.
Annals of human genetics.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2011.00654.x
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Zabaneh, D;
Kumari, M;
Sandhu, M;
Wareham, N;
Wainwright, N;
Papamarkou, T;
Hopewell, J;
Clarke, R;
LI, K;
Palmen, J;
+16 more...
Talmud, PJ;
Kronenberg, F;
Lamina, C;
Summerer, M;
Paulweber, B;
Price, J;
Fowkes, G;
Stewart, M;
Drenos, F;
Shah, S;
Shah, T;
Casas, JP;
Kivimaki, M;
Whittaker, J;
Hingorani, AD;
Humphries, SE;
(2011)
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
Atherosclerosis, 217 (2).
pp. 447-451.
ISSN 0021-9150
DOI: https://doi.org/10.1016/j.atherosclerosis.2011.04.015
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de Iorio, M;
Newcombe, PJ;
Tachmazidou, I;
Verzilli, CJ;
Whittaker, JC;
(2011)
Bayesian Semiparametric Meta-Analysis for Genetic Association Studies.
Genetic epidemiology, 35 (5).
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ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20581
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2010
Burgess, S;
Thompson, SG;
CRP CHD Genetics Collaboration;
Burgess, S;
Thompson, SG;
Andrews, G;
Samani, NJ;
Hall, A;
Whincup, P;
Morris, R;
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Lawlor, DA;
Davey Smith, G;
Timpson, N;
Ebrahim, S;
Ben-Shlomo, Y;
Davey Smith, G;
Timpson, N;
Brown, M;
Ricketts, S;
Sandhu, M;
Reiner, A;
Psaty, B;
Lange, L;
Cushman, M;
Hung, J;
Thompson, P;
Beilby, J;
Warrington, N;
Palmer, LJ;
Nordestgaard, BG;
Tybjaerg-Hansen, A;
Zacho, J;
Wu, C;
Lowe, G;
Tzoulaki, I;
Kumari, M;
Sandhu, M;
Yamamoto, JF;
Chiodini, B;
Franzosi, M;
Hankey, GJ;
Jamrozik, K;
Palmer, L;
Rimm, E;
Pai, J;
Psaty, B;
Heckbert, S;
Bis, J;
Anand, S;
Engert, J;
Collins, R;
Clarke, R;
Melander, O;
Berglund, G;
Ladenvall, P;
Johansson, L;
Jansson, JH;
Hallmans, G;
Hingorani, A;
Humphries, S;
Rimm, E;
Manson, J;
Pai, J;
Watkins, H;
Clarke, R;
Hopewell, J;
Saleheen, D;
Frossard, R;
Danesh, J;
Sattar, N;
Robertson, M;
Shepherd, J;
Schaefer, E;
Hofman, A;
Witteman, JC;
Kardys, I;
Ben-Shlomo, Y;
Davey Smith, G;
Timpson, N;
de Faire, U;
Bennet, A;
Sattar, N;
Ford, I;
Packard, C;
Kumari, M;
Manson, J;
Lawlor, DA;
Davey Smith, G;
Anand, S;
Collins, R;
Casas, JP;
Danesh, J;
Davey Smith, G;
Franzosi, M;
Hingorani, A;
Lawlor, DA;
Manson, J;
Nordestgaard, BG;
Samani, NJ;
Sandhu, M;
Smeeth, L;
Wensley, F;
Anand, S;
Bowden, J;
Burgess, S;
Casas, JP;
Di Angelantonio, E;
Engert, J;
Gao, P;
Shah, T;
Smeeth, L;
Thompson, SG;
Verzilli, C;
Walker, M;
Whittaker, J;
Hingorani, A;
Danesh, J;
(2010)
Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.
Statistics in medicine, 29 (12).
pp. 1298-311.
ISSN 0277-6715
DOI: https://doi.org/10.1002/sim.3843
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Dixon, PH;
Wadsworth, CA;
Chambers, J;
Donnelly, J;
Cooley, SM;
Jarvis, S;
Kubitz, R;
Lammert, F;
Marschall, HU;
Glantz, A;
+4 more...
Khan, SA;
Whittaker, J;
Geary, M;
Williamson, C;
(2010)
The Role of Common Genetic Variation around Six Candidate Loci for Susceptibility to Intrahepatic Cholestasis of Pregnancy.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/902
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Fararouei, M;
Robertson, C;
Whittaker, J;
Sovio, U;
Ruokonen, A;
Pouta, A;
Hartikainen, AL;
Jarvelin, MR;
Hypponen, E;
(2010)
Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years.
The British journal of nutrition.
pp. 1-6.
ISSN 0007-1145
DOI: https://doi.org/10.1017/S0007114510002175
Mann, Andrea Gail;
(2010)
Estimating the impact of influenza vaccination and antigenic drift on influenza-related morbidity and mortality in England & Wales using hidden Markov models.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.00682415
Morris, DL;
Roberts, AL;
Witherden, AS;
Tarzi, R;
Barros, P;
Whittaker, JC;
Cook, TH;
Aitman, TJ;
Vyse, TJ;
(2010)
Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus.
European journal of human genetics, 18 (9).
pp. 1027-1031.
ISSN 1018-4813
DOI: https://doi.org/10.1038/ejhg.2010.56
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Nonyane, BA;
Whittaker, JC;
(2010)
A variance components factor model for genetic association studies: A Bayesian analysis.
Genetic epidemiology.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20503
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Shah, S;
Drenos, F;
Shah, T;
Palmen, J;
Sofat, R;
Kumari, M;
Pallas, J;
MacFarlane, P;
Whittaker, J;
Talmud, P;
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Humphries, S;
Hingorani, A;
(2010)
Identification of Genes Associated with Qt Interval Using the 50k Cardio-Metabolic Snp Chip: Results from the Whitehall II Study.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/2938
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Shah, T;
Newcombe, P;
Smeeth, L;
Addo, J;
Casas, JP;
Whittaker, J;
Miller, MA;
Tinworth, L;
Jeffery, S;
Strazzullo, P;
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Cappuccio, FP;
Hingorani, AD;
(2010)
Ancestry as a Determinant of Mean Population C-Reactive Protein Values: Implications for Cardiovascular Risk Prediction.
Circulation Cardiovascular genetics, 3 (5).
pp. 436-44.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.110.957431
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Sofat, R;
Casas, JP;
Kumari, M;
Talmud, PJ;
Ireland, H;
Kivimaki, M;
Marmot, M;
Hughes, AD;
Thom, S;
Ebrahim, S;
+5 more...
Whittaker, JC;
Smeeth, L;
Lawlor, DA;
Humphries, SE;
Hingorani, AD;
(2010)
Genetic variation in complement factor H and risk of coronary heart disease: Eight new studies and a meta-analysis of around 48,000 individuals.
Atherosclerosis.
ISSN 0021-9150
DOI: https://doi.org/10.1016/j.atherosclerosis.2010.07.021
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2009
Balchin, I;
Whittaker, JC;
Lamont, RF;
Steer, PJ;
(2009)
The effect of exclusion of cases with unrecorded best estimate of gestational age on the estimates of preterm birth rate.
BJOG, 116 (9).
pp. 1218-1224.
ISSN 1470-0328
DOI: https://doi.org/10.1111/j.1471-0528.2009.02184.x
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Casas, Juan-Pablo;
(2009)
Mendelian randomisation and cardiovascular disease.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.00682420
Chapman, JM;
Onnie, CM;
Prescott, NJ;
Fisher, SA;
Mansfield, JC;
Mathew, CG;
Lewis, CM;
Verzilli, CJ;
Whittaker, JC;
(2009)
Searching for Genotype-Phenotype Structure: Using Hierarchical Log-Linear Models in Crohn Disease.
American journal of human genetics, 84 (2).
pp. 178-87.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2008.12.015
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Clarke, MC;
Tanskanen, A;
Huttunen, M;
Whittaker, JC;
Cannon, M;
(2009)
Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia.
The American journal of psychiatry, 166 (9).
pp. 1025-30.
ISSN 0002-953X
DOI: https://doi.org/10.1176/appi.ajp.2009.08010031
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Doudney, K;
Grinham, J;
Whittaker, J;
Lynch, SA;
Thompson, D;
Moore, GE;
Copp, AJ;
Greene, NDE;
Stanier, P;
(2009)
Evaluation of Folate Metabolism Gene Polymorphisms as Risk Factors for Open and Closed Neural Tube Defects.
American journal of medical genetics Part A, 149A (7).
pp. 1585-1589.
ISSN 1552-4825
DOI: https://doi.org/10.1002/ajmg.a.32937
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Khalique, L;
Ayhan, A;
Whittaker, JC;
Singh, N;
Jocobs, IJ;
Gayther, SA;
Ramus, SJ;
(2009)
The clonal evolution of metastases from primary serous epithelial ovarian cancers.
International journal of cancer Journal international du cancer, 124 (7).
pp. 1579-1586.
ISSN 0020-7136
DOI: https://doi.org/10.1002/ijc.24148
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Lunn, DJ;
Best, N;
Whittaker, JC;
(2009)
Generic reversible jump MCMC using graphical models.
Statistics and computing, 19 (4).
pp. 395-408.
ISSN 0960-3174
DOI: https://doi.org/10.1007/s11222-008-9100-0
Full text not available from this repository.
Mead, S;
Poulter, M;
Uphill, J;
Beck, J;
Whitfield, J;
Webb, TEF;
Campbell, T;
Adamson, G;
Deriziotis, P;
Tabrizi, SJ;
+5 more...
Hummerich, H;
Verzilli, C;
Alpers, MP;
Whittaker, JC;
Collinge, J;
(2009)
Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.
Lancet neurology, 8 (1).
pp. 57-66.
ISSN 1474-4422
DOI: https://doi.org/10.1016/S1474-4422(08)70265-5
Mead, S;
Whitfield, J;
Poulter, M;
Shah, P;
Uphill, J;
Campbell, T;
Al-Dujaily, H;
Hummerich, H;
Beck, J;
Mein, CA;
+4 more...
Verzilli, C;
Whittaker, J;
Alpers, MP;
Collinge, J;
(2009)
A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure.
The New England journal of medicine, 361 (21).
pp. 2056-65.
ISSN 0028-4793
DOI: https://doi.org/10.1056/NEJMoa0809716
Newcombe, PJ;
Verzilli, C;
Casas, JP;
Hingorani, AD;
Smeeth, L;
Whittaker, JC;
(2009)
Multilocus Bayesian Meta-Analysis of Gene-Disease Associations.
American journal of human genetics, 84 (5).
pp. 567-80.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2009.04.001
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Nonyane, BA;
Nitsch, D;
Whittaker, JC;
Sofat, R;
Smeeth, L;
Chakravarthy, U;
Fletcher, AE;
(2009)
An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.
Investigative ophthalmology & visual science, 51 (5).
pp. 2393-402.
ISSN 0146-0404
DOI: https://doi.org/10.1167/iovs.09-4228
Full text not available from this repository.
Rao, R;
Tah, V;
Casas, JP;
Hingorani, A;
Whittaker, J;
Smeeth, L;
Sharma, P;
(2009)
Ischaemic Stroke Subtypes and Their Genetic Basis: A Comprehensive Meta-Analysis of Small and Large Vessel Stroke.
European neurology, 61 (2).
pp. 76-86.
ISSN 0014-3022
DOI: https://doi.org/10.1159/000177939
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Rhodes, B;
Hunnangkul, S;
Morris, DL;
Hsaio, LC;
Graham, DSC;
Nitsch, D;
Whittaker, JC;
Vyse, TJ;
(2009)
The heritability and genetics of complement C3 expression in UK SLE families.
Genes and immunity, 10 (5).
pp. 525-530.
ISSN 1466-4879
DOI: https://doi.org/10.1038/gene.2009.23
Full text not available from this repository.
Shah, S;
Drenos, F;
Shah, T;
Palmen, J;
Verzilli, C;
Sofat, R;
Kumari, M;
Kivamaki, M;
Pallas, J;
MacFarlane, P;
+4 more...
Whittaker, J;
Talmud, PJ;
Humphries, SE;
Hingorani, AD;
(2009)
IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY.
[Conference or Workshop Item]
https://doi.org/10.1016/j.atherosclerosis.2009.09.058
Full text not available from this repository.
Sovio, U;
Bennett, AJ;
Millwood, IY;
Molitor, J;
O'Reilly, PF;
Timpson, NJ;
Kaakinen, M;
Laitinen, J;
Haukka, J;
Pillas, D;
+13 more...
Tzoulaki, I;
Molitor, J;
Hoggart, C;
Coin, LJ;
Whittaker, J;
Pouta, A;
Hartikainen, AL;
Freimer, NB;
Widen, E;
Peltonen, L;
Elliott, P;
McCarthy, MI;
Jarvelin, MR;
(2009)
Genetic Determinants of Height Growth Assessed Longitudinally from Infancy to Adulthood in the Northern Finland Birth Cohort 1966.
PLoS genetics, 5 (3).
e1000409.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1000409
Talmud, PJ;
Drenos, F;
Shah, S;
Shah, T;
Palmen, J;
Verzilli, C;
Gaunt, TR;
Pallas, J;
Lovering, R;
LI, K;
+27 more...
Casas, JP;
Sofat, R;
Kumari, M;
Rodriguez, S;
Johnson, T;
Newhouse, SJ;
Dominiczak, A;
Samani, NJ;
Caulfield, M;
Sever, P;
Stanton, A;
Shields, DC;
Padmanabhan, S;
Melander, O;
Hastie, C;
Delles, C;
Ebrahim, S;
Marmot, MG;
Smith, GD;
Lawlor, DA;
Munroe, PB;
Day, IN;
Kivimaki, M;
Whittaker, J;
Humphries, SE;
Hingorani, AD;
Consortium, AINIB;
(2009)
Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip.
American journal of human genetics, 85 (5).
pp. 628-642.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2009.10.014
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Webb, TEF;
Whittaker, J;
Collinge, J;
Mead, S;
(2009)
Age of Onset and Death in Inherited Prion Disease Are Heritable.
American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4).
pp. 496-501.
ISSN 1552-4841
DOI: https://doi.org/10.1002/ajmg.b.30844
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2008
Balchin, I;
Whittaker, JC;
Lamont, RF;
Steer, PJ;
(2008)
Timing of Planned Cesarean Delivery by Racial Group.
Obstetrics and gynecology, 111 (3).
pp. 659-666.
ISSN 0029-7844
DOI: https://doi.org/10.1097/AOG.0b013e318163cd55
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Barton, SJ;
Whittaker, JC;
(2008)
Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors.
Mass spectrometry reviews, 28 (1).
pp. 177-87.
ISSN 0277-7037
DOI: https://doi.org/10.1002/mas.20188
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Chadeau-Hyam, M;
Hoggart, CJ;
O'Reilly, PF;
Whittaker, JC;
De Iorio, M;
Balding, DJ;
(2008)
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples.
BMC bioinformatics, 9 (1).
p. 364.
ISSN 1471-2105
DOI: https://doi.org/10.1186/1471-2105-9-364
Chapman, J;
Whittaker, J;
(2008)
Analysis of multiple SNPs in a candidate gene or region.
Genetic epidemiology, 32 (6).
pp. 560-6.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20330
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Chapman, JM;
Onnie, C;
Prescott, N;
Fisher, S;
Lewis, C;
Mathew, C;
Verzilli, CJ;
Whittaker, JC;
(2008)
Searching for genotype-phenotype structure: Trying to understand Crohn's disease.
Annals of human genetics, 72.
p. 688.
ISSN 0003-4800
http://researchonline.lshtm.ac.uk/id/eprint/7101
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Elmasry, K;
Ramus, S;
Whittaker, J;
Luo, Z;
Gammerman, A;
Lu, K;
Ayhan, A;
Singh, N;
McGluggage, G;
Jacobs, I;
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Gayther, S;
(2008)
Genetic diagnosis and clinical outcome in patients with synchronous ovarian and endometrial cancer.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/8017
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Graham, DS;
Graham, RR;
Manku, H;
Wong, AK;
Whittaker, JC;
Gaffney, PM;
Moser, KL;
Rioux, JD;
Altshuler, D;
Behrens, TW;
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Vyse, TJ;
(2008)
Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.
Nature genetics, 40 (1).
pp. 83-9.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng.2007.47
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Hoggart, CJ;
Clark, TG;
de Lorio, M;
Whittaker, JC;
Balding, DJ;
(2008)
Genome-wide significance for dense SNP and resequencing data.
Genetic epidemiology, 32 (2).
pp. 179-185.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20292
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Hoggart, CJ;
Whittaker, JC;
De Iorio, M;
Balding, DJ;
(2008)
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies.
PLoS genetics, 4 (7).
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DOI: https://doi.org/10.1371/journal.pgen.1000130
Hunnangkul, S;
Nitsch, D;
Rhodes, B;
Chadha, S;
Roberton, CA;
Pessôa-Lopes, P;
Norsworthy, PJ;
Fernando, MM;
Charles, P;
Mackworth-Young, C;
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Isenberg, DA;
Whittaker, JC;
Vyse, TJ;
(2008)
Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus.
Arthritis and rheumatism, 58 (4).
pp. 1116-1124.
ISSN 0004-3591
DOI: https://doi.org/10.1002/art.23400
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Newcombe, PJ;
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Pablo-Casas, J;
Whittaker, J;
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Meta-analysis of gene/disease association studies.
Annals of human genetics, 72.
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ISSN 0003-4800
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Peck, G;
Smeeth, L;
Whittaker, J;
Casas, JP;
Hingorani, A;
Sharma, P;
(2008)
The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults.
PloS one, 3 (11).
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ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0003691
Ramus, SJ;
Elmasry, K;
Luo, Z;
Gammerman, A;
Lu, K;
Ayhan, A;
Singh, N;
McCluggage, WG;
Jacobs, IJ;
Whittaker, JC;
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Gayther, SA;
(2008)
Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.
Clinical cancer research, 14 (18).
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ISSN 1078-0432
DOI: https://doi.org/10.1158/1078-0432.CCR-08-0373
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Rhodes, B;
Meek, J;
Whittaker, JC;
Vyse, TJ;
(2008)
Quantification of the genetic component of basal C-reactive protein expression in SLE nuclear families.
Annals of human genetics, 72.
pp. 611-620.
ISSN 0003-4800
http://researchonline.lshtm.ac.uk/id/eprint/7103
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Rhodes, B;
Meek, J;
Whittaker, JC;
Vyse, TJ;
(2008)
Quantification of the Genetic Component of Basal C-Reactive Protein Expression in SLE Nuclear Families.
Annals of human genetics, 72 (Pt 5).
pp. 611-20.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2008.00444.x
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Rhodes, B;
Morris, DL;
Subrahmanyan, L;
Aubin, C;
de Leon, CFM;
Kelly, JF;
Evans, DA;
Whittaker, JC;
Oksenberg, JR;
de Jager, PL;
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Vyse, TJ;
(2008)
Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach.
Human genetics, 123 (6).
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ISSN 0340-6717
DOI: https://doi.org/10.1007/s00439-008-0517-5
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Verzilli, C;
Shah, T;
Casas, JP;
Chapman, J;
Sandhu, M;
Debenham, SL;
Boekholdt, MS;
Khaw, KT;
Wareham, NJ;
Judson, R;
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Benjamin, EJ;
Kathiresan, S;
Larson, MG;
Rong, J;
Sofat, R;
Humphries, SE;
Smeeth, L;
Cavalleri, G;
Whittaker, JC;
Hingorani, AD;
(2008)
Bayesian meta-analysis of genetic association studies with different sets of markers.
American journal of human genetics, 82 (4).
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ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2008.01.016
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Webb, TE;
Whittaker, J;
Collinge, J;
Mead, S;
(2008)
Age of onset and death in inherited prion disease are heritable.
American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4).
pp. 496-501.
ISSN 1552-4841
DOI: https://doi.org/10.1002/ajmg.b.30844
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2007
Apostolidou, S;
Abu-Amero, S;
O'Donoghue, K;
Frost, J;
Olafsdottir, O;
Chavele, KM;
Whittaker, JC;
Loughna, P;
Stanier, P;
Moore, GF;
(2007)
Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight.
Journal of molecular medicine (Berlin, Germany), 85 (4).
pp. 379-387.
ISSN 0946-2716
DOI: https://doi.org/10.1007/s00109-006-0131-8
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Ariyaratnam, R;
Casas, JP;
Whittaker, J;
Smeeth, L;
Hingorani, AD;
Sharma, P;
(2007)
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.
PLoS medicine, 4 (4).
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ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.0040131
Baksh, MF;
Balding, DJ;
Vyse, TJ;
Whittaker, JC;
(2007)
Family-based association analysis with ordered categorical phenotypes, covariates and interactions.
Genetic epidemiology, 31 (1).
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ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20183
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Balchin, I;
Whittaker, JC;
Patel, R;
Lamont, RF;
Steer, PJ;
(2007)
Racial variation in the association between gestational age and perinatal mortality: prospective study.
BMJ (Clinical research ed), 334 (7598).
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ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.39132.482025.80
Barton, SJ;
Richardson, S;
Perkins, DN;
Bellahn, I;
Bryant, TN;
Whittaker, JC;
(2007)
Using Statistical Models To Identify Factors That Have a Role in Defining the Abundance of Ions Produced by Tandem MS.
Analytical chemistry, 79 (15).
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ISSN 0003-2700
DOI: https://doi.org/10.1021/ac0700272
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Campbell, O;
Coleman, M;
Cousens, S;
Doyle, P;
Elbourne, D;
Evans, S;
Filteau, S;
Fine, PE;
Glynn, JR;
Grundy, E;
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Haines, A;
Hall, AJ;
Hayes, R;
Kenward, M;
Kirkwood, B;
Lamping, DL;
Lee, K;
Leon, D;
Mabey, D;
McKee, M;
Meade, T;
Milligan, P;
Mills, A;
Patel, V;
Peto, J;
Pocock, S;
Prentice, A;
Roberts, I;
Rodrigues, LC;
dos Santos Silva, I;
Smeeth, L;
Sondorp, E;
De Stavola, B;
Timaeus, IM;
Walt, G;
Whittaker, J;
Wilkinson, P;
Zaba, B;
(2007)
Reed Elsevier and the arms trade revisited.
Lancet, 369 (9566).
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DOI: https://doi.org/10.1016/S0140-6736(07)60484-X
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Chapman, J;
Verzilli, C;
Whittaker, J;
(2007)
Large scale association studies: Implications for FDRs and a simple Bayesian alternative.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/8555
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Drenos, F;
Whittaker, JC;
Humphries, SE;
(2007)
The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk.
Annals of human genetics, 71 (Pt 5).
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ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2007.00359.x
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Hoggart, C;
de Iorio, M;
Whittaker, J;
Balding, D;
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Bayesian shrinkage priors for detecting multiple causal variants from genome-wide association studies.
Annals of human genetics, 71.
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Hoggart, CJ;
Chadeau-Hyam, M;
Clark, TG;
Lampariello, R;
Whittaker, JC;
De Iorio, M;
Balding, DJ;
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Sequence-level population simulations over large genomic regions.
Genetics, 177 (3).
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DOI: https://doi.org/10.1534/genetics.106.069088
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Hoggart, CJ;
de Iorio, M;
Whittaker, JC;
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Simultaneous analysis of genome-wide SNP data.
Genetic epidemiology, 31 (6).
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Sharma, P;
Whittaker, J;
Casas, JP;
Hingorani, AD;
Ariyaratnam, R;
(2007)
Genetics of ischaemic stroke in ethnic minorities.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/9688
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Van Mil, SW;
Milona, A;
Dixon, PH;
Mullenbach, R;
Geenes, VL;
Chambers, J;
Shevchuk, V;
Moore, GE;
Lammert, F;
Glantz, AG;
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Mattsson, LA;
Whittaker, J;
Parker, MG;
White, R;
Williamson, C;
(2007)
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.
Gastroenterology, 133 (2).
pp. 507-16.
ISSN 0016-5085
DOI: https://doi.org/10.1053/j.gastro.2007.05.015
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Verzilli, C;
Chapman, J;
Hingorani, A;
Pablo-Casas, J;
Shah, T;
Smeeth, L;
Whittaker, J;
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Bayesian meta analysis of genetic association studies with different sets of markers.
Annals of human genetics, 71.
pp. 552-553.
ISSN 0003-4800
http://researchonline.lshtm.ac.uk/id/eprint/8490
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Whittaker, JC;
Chapman, J;
(2007)
Analysis of multiple SNPs in a candidate gene or region.
Genetic epidemiology, 31 (6).
p. 650.
ISSN 0741-0395
http://researchonline.lshtm.ac.uk/id/eprint/8560
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2006
Apostolidou, S;
Abu-Amero, S;
O'Donoghue, K;
Olafsdottir, O;
Chavele, KM;
Frost, J;
Whittaker, JC;
Loughna, P;
Stanier, P;
Moore, GE;
(2006)
Elevated maternal expression of the imprinted PHLDA2 gene is associated with low birth weight.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/9687
Full text not available from this repository.
Baksh, MF;
Balding, DJ;
Vyse, TJ;
Whittaker, JC;
(2006)
A likelihood ratio approach to family-based association studies with covariates.
Annals of human genetics, 70 (Pt 1).
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ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1529-8817.2005.00189.x
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Fletcher, O;
Johnson, N;
Palles, C;
Dos Santos Silva, I;
McCormack, V;
Whittaker, J;
Ashworth, A;
Peto, J;
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Inconsistent association between the STK15 f31I genetic polymorphism and breast cancer risk.
Journal of the National Cancer Institute, 98 (14).
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ISSN 0027-8874
DOI: https://doi.org/10.1093/jnci/djj268
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Graham, DS;
Wong, AK;
McHugh, NJ;
Whittaker, JC;
Vyse, TJ;
(2006)
Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study.
Human molecular genetics, 15 (21).
pp. 3195-205.
ISSN 0964-6906
DOI: https://doi.org/10.1093/hmg/ddl395
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Lunn, DJ;
Whittaker, JC;
Best, N;
(2006)
A Bayesian toolkit for genetic association studies.
Genetic epidemiology, 30 (3).
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Nitsch, D;
Molokhia, M;
Smeeth, L;
De Stavola, BL;
Whittaker, JC;
Leon, DA;
(2006)
Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials.
American journal of epidemiology, 163 (5).
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ISSN 0002-9262
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Rohrmann, S;
Linseisen, J;
Boshuizen, HC;
Whittaker, J;
Agudo, A;
Vineis, P;
Boffetta, P;
Jensen, MK;
Olsen, A;
Overvad, K;
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Tjonneland, A;
Boutron-Ruault, MC;
Clavel-Chapelon, F;
Bergmann, MM;
Boeing, H;
Allen, N;
Key, T;
Bingham, S;
Khaw, KT;
Kyriazi, G;
Soukara, S;
Trichopoulou, A;
Panico, S;
Palli, D;
Sieri, S;
Tumino, R;
Peeters, PHM;
Bueno-de-Mesquita, HB;
Buchner, FL;
Gram, IT;
Lund, E;
Ardanaz, E;
Chirlaque, MD;
Dorronsoro, M;
Perez, MJS;
Quiros, JR;
Berglund, G;
Janzon, L;
Rasmuson, T;
Weinehall, L;
Ferrari, P;
Jenab, M;
Norat, T;
Riboli, E;
(2006)
Ethanol intake and risk of lung cancer in the European prospective investigation into cancer and nutrition (EPIC).
American journal of epidemiology, 164 (11).
pp. 1103-1114.
ISSN 0002-9262
DOI: https://doi.org/10.1093/aje/kwj326
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Underwood, SL;
Christoforou, A;
Thomson, PA;
Wray, NR;
Tenesa, A;
Whittaker, J;
Adams, RA;
le Hellard, S;
Morris, SW;
Blackwood, DHR;
+3 more...
Muir, WJ;
Porteous, DJ;
Evans, KL;
(2006)
Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.
Molecular psychiatry, 11 (4).
pp. 384-394.
ISSN 1359-4184
DOI: https://doi.org/10.1038/sj.mp.4001786
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Verzilli, CJ;
Stallard, N;
Whittaker, JC;
(2006)
Bayesian graphical models for genomewide association studies.
American journal of human genetics, 79 (1).
pp. 100-112.
ISSN 0002-9297
DOI: https://doi.org/10.1086/505313
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Waldron, ER;
Whittaker, JC;
Balding, DJ;
(2006)
Fine mapping of disease genes via haplotype clustering.
Genetic epidemiology, 30 (2).
pp. 170-9.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20134
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2005
Christoforou, A;
Underwood, SL;
Hellard, SL;
Wray, NR;
Morris, SW;
Tenesa, A;
Thomson, PA;
Whittaker, J;
Blackwood, DH;
Muir, WJ;
+2 more...
Porteous, DJ;
Evans, KL;
(2005)
Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.
American journal of medical genetics Part B, Neuropsychiatric genetics, 138B (1).
p. 47.
ISSN 1552-4841
http://researchonline.lshtm.ac.uk/id/eprint/12455
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Hubner, N;
Wallace, CA;
Zimdahl, H;
Petretto, E;
Schulz, H;
Maciver, F;
Mueller, M;
Hummel, O;
Monti, J;
Zidek, V;
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Musilova, A;
Kren, V;
Causton, H;
Game, L;
Born, G;
Schmidt, S;
Müller, A;
Cook, SA;
Kurtz, TW;
Whittaker, J;
Pravenec, M;
Aitman, TJ;
(2005)
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.
Nature genetics, 37 (3).
pp. 243-53.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng1522
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Kelly, PJ;
Stallard, N;
Whittaker, JC;
(2005)
Statistical design and analysis of pharmacogenetic trials.
Statistics in medicine, 24 (10).
pp. 1495-508.
ISSN 0277-6715
DOI: https://doi.org/10.1002/sim.2052
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Pardi, F;
Lewis, CM;
Whittaker, JC;
(2005)
SNP selection for association studies: Maximizing power across SNP choice and study size.
Annals of human genetics, 69.
pp. 733-746.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1529-8817.2005.00202.x
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Pardi, F;
Sibly, RM;
Wilkinson, MJ;
Whittaker, JC;
(2005)
On the structural differences between markers and genomic AC microsatellites.
Journal of molecular evolution, 60 (5).
pp. 688-93.
ISSN 0022-2844
DOI: https://doi.org/10.1007/s00239-004-0274-6
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Russell, AI;
Graham, DS;
Chadha, S;
Roberton, C;
Fernandez-Hart, T;
Griffiths, B;
D'Cruz, D;
Nitsch, D;
Whittaker, JC;
Vyse, TJ;
(2005)
No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE.
Genes and immunity, 6 (5).
pp. 422-9.
ISSN 1466-4879
DOI: https://doi.org/10.1038/sj.gene.6364222
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Verzilli, CJ;
Stallard, N;
Whittaker, JC;
(2005)
Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions.
Genetic epidemiology, 28 (4).
pp. 313-25.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20072
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Verzilli, CJ;
Whittaker, JC;
Stallard, N;
Chasman, D;
(2005)
A hierarchical Bayesian model for predicting the functional consequences of amino acid polymorphisms.
Applied statistics, 54.
pp. 191-207.
ISSN 0035-9254
DOI: https://doi.org/10.1111/j.1467-9876.2005.00478.x
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Waldron, ERB;
Whittaker, JC;
Balding, DJ;
(2005)
A spatial clustering approach to fine-mapping of disease genes.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/6482
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2004
Balchin, I;
Whittaker, JC;
Steer, PJ;
Lamont, RF;
(2004)
Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate.
BJOG, 111 (2).
pp. 160-3.
ISSN 1470-0328
DOI: https://doi.org/10.1046/j.1471-0528.2003.00026.x
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Morris, AP;
Whittaker, JC;
Balding, DJ;
(2004)
Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data.
American journal of human genetics, 74 (5).
pp. 945-53.
ISSN 0002-9297
DOI: https://doi.org/10.1086/420773
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Russell, AI;
Cunninghame Graham, DS;
Shepherd, C;
Roberton, CA;
Whittaker, J;
Meeks, J;
Powell, RJ;
Isenberg, DA;
Walport, MJ;
Vyse, TJ;
(2004)
Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus.
Human molecular genetics, 13 (1).
pp. 137-47.
ISSN 0964-6906
DOI: https://doi.org/10.1093/hmg/ddh021
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2003
Byng, MC;
Fisher, SA;
Lewis, CM;
Whittaker, JC;
(2003)
Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study.
BMC genetics, 4 Supp.
S4.
ISSN 1471-2156
DOI: https://doi.org/10.1186/1471-2156-4-S1-S4
Byng, MC;
Whittaker, JC;
Cuthbert, AP;
Mathew, CG;
Lewis, CM;
(2003)
SNP subset selection for genetic association studies.
Annals of human genetics, 67 (Pt 6).
pp. 543-56.
ISSN 0003-4800
DOI: https://doi.org/10.1046/j.1529-8817.2003.00055.x
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Denham, MC;
Whittaker, JC;
(2003)
A Bayesian approach to disease gene location using allelic association.
Biostatistics (Oxford, England), 4 (3).
pp. 399-409.
ISSN 1465-4644
DOI: https://doi.org/10.1093/biostatistics/4.3.399
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Morris, AP;
Whittaker, JC;
Xu, CF;
Hosking, LK;
Balding, DJ;
(2003)
Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America, 100 (23).
pp. 13442-6.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.2235031100
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Sibly, RM;
Meade, A;
Boxall, N;
Wilkinson, MJ;
Corne, DW;
Whittaker, JC;
(2003)
The structure of interrupted human AC microsatellites.
Molecular biology and evolution, 20 (3).
pp. 453-9.
ISSN 0737-4038
DOI: https://doi.org/10.1093/molbev/msg056
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Whittaker, JC;
Gharani, N;
Hindmarsh, P;
McCarthy, MI;
(2003)
Estimation and testing of parent-of-origin effects for quantitative traits.
American journal of human genetics, 72 (4).
pp. 1035-9.
ISSN 0002-9297
DOI: https://doi.org/10.1086/374382
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Whittaker, JC;
Harbord, RM;
Boxall, N;
Mackay, I;
Dawson, G;
Sibly, RM;
(2003)
Likelihood-based estimation of microsatellite mutation rates.
Genetics, 164 (2).
pp. 781-7.
ISSN 0016-6731
http://researchonline.lshtm.ac.uk/id/eprint/13639
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2002
Lange, C;
Whittaker, JC;
(2002)
Generalised estimating equations: a hybrid approach for mean parameters in multivariate regression models.
Statistical Modelling, 2.
pp. 163-181.
ISSN 1477-0342
http://researchonline.lshtm.ac.uk/id/eprint/13386
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Lange, C;
Whittaker, JC;
(2002)
Model selection for quasi-likelihood: a new approach.
In: Gregori, D; Cameci, G; Friedl, H; Ferligoi, A; Wedlin, A, (eds.)
Correlated Data Modeling.
Economia/Ricerche, Collana.
http://researchonline.lshtm.ac.uk/id/eprint/13385
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Morris, AP;
Whittaker, JC;
Balding, DJ;
(2002)
Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies.
American journal of human genetics, 70 (3).
pp. 686-707.
ISSN 0002-9297
DOI: https://doi.org/10.1086/339271
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2001
Lange, C;
Whittaker, JC;
(2001)
Mapping quantitative trait Loci using generalized estimating equations.
Genetics, 159 (3).
pp. 1325-37.
ISSN 0016-6731
http://researchonline.lshtm.ac.uk/id/eprint/13633
Full text not available from this repository.
Lange, C;
Whittaker, JC;
(2001)
On prediction of genetic values in marker-assisted selection.
Genetics, 159 (3).
pp. 1375-81.
ISSN 0016-6731
http://researchonline.lshtm.ac.uk/id/eprint/13634
Full text not available from this repository.
Lewis, CM;
Pinel, T;
Whittaker, JC;
Handyside, AH;
(2001)
Controlling misdiagnosis errors in preimplantation genetic diagnosis: a comprehensive model encompassing extrinsic and intrinsic sources of error.
Human reproduction (Oxford, England), 16 (1).
pp. 43-50.
ISSN 0268-1161
DOI: https://doi.org/10.1093/humrep/16.1.43
Full text not available from this repository.
Sibly, RM;
Whittaker, JC;
Talbot, M;
(2001)
A maximum-likelihood approach to fitting equilibrium models of microsatellite evolution.
Molecular biology and evolution, 18 (3).
pp. 413-7.
ISSN 0737-4038
http://researchonline.lshtm.ac.uk/id/eprint/13632
Full text not available from this repository.
Whittaker, JC;
(2001)
Marker assisted selection and introgression.
In: Balding, DJ; Bishop, M; Cannings, C, (eds.)
Handbook of Statistical Genetics.
Wiley.
http://researchonline.lshtm.ac.uk/id/eprint/13387
Full text not available from this repository.
Whittaker, JC;
Morris, AP;
(2001)
Family-based tests of association and/or linkage.
Annals of human genetics, 65 (Pt 5).
pp. 407-19.
ISSN 0003-4800
DOI: https://doi.org/10.1017/S0003480001008818
Full text not available from this repository.