Items where Author is "Alsford, S"

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Number of items: 37.

2018

Thomas, James; Baker, Nicola; Hutchinson, Sebastian; Dominicus, Caia; Trenaman, Anna; Glover, Lucy; Alsford, Sam; Horn, David; (2018) Insights into antitrypanosomal drug mode-of-action from cytology-based profiling. PLOS NEGLECTED TROPICAL DISEASES, 12 (11). ISSN 1935-2735 DOI: https://doi.org/10.1371/journal.pntd.0006980
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2017

Macedo, JP; Currier, RB; Wirdnam, C; Horn, D; Alsford, S; Rentsch, D; (2017) Ornithine uptake and the modulation of drug sensitivity in Trypanosoma brucei. FASEB journal. ISSN 0892-6638 DOI: https://doi.org/10.1096/fj.201700311R
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Meredith, EL; Kumar, A; Konno, A; Szular, J; Alsford, S; Seifert, K; Horn, D; Wilkinson, SR; (2017) Distinct activation mechanisms trigger the trypanocidal activity of DNA damaging prodrugs. Molecular microbiology. ISSN 0950-382X DOI: https://doi.org/10.1111/mmi.13767
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Stortz, JA; Serafim, TD; Alsford, S; Wilkes, J; Fernandez-Cortes, F; Hamilton, G; Briggs, E; Lemgruber, L; Horn, D; Mottram, JC; +1 more... McCulloch, R; (2017) Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei. PLoS pathogens, 13 (7). e1006477. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1006477
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2016

Glover, L; Hutchinson, S; Alsford, S; Horn, D; (2016) VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes. Proceedings of the National Academy of Sciences of the United States of America. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1600344113
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Maishman, L; Obado, SO; Alsford, S; Bart, JM; Chen, WM; Ratushny, AV; Navarro, M; Horn, D; Aitchison, JD; Chait, BT; +2 more... Rout, MP; Field, MC; (2016) Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression. Nucleic acids research. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkw751
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2015

Alsford, S; (2015) Subverting lysosomal function in Trypanosoma brucei. Microbial cell (Graz, Austria), 2 (8). pp. 259-261. ISSN 2311-2638 DOI: https://doi.org/10.15698/mic2015.08.222
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Zoltner, M; Leung, KF; Alsford, S; Horn, D; Field, MC; (2015) Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes. PLoS pathogens, 11 (10). e1005236. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1005236
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2014

Alsford, S; Currier, RB; Guerra-Assunção, JA; Clark, TG; Horn, D; (2014) Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei. PLoS pathogens, 10 (5). e1004130. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1004130
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Glover, L; Alsford, S; Baker, N; Turner, DJ; Sanchez-Flores, A; Hutchinson, S; Hertz-Fowler, C; Berriman, M; Horn, D; (2014) Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes. Nature protocols, 10 (1). pp. 106-133. ISSN 1754-2189 DOI: https://doi.org/10.1038/nprot.2015.005 Full text not available from this repository.

2013

Glover, L; Hutchinson, S; Alsford, S; McCulloch, R; Field, MC; Horn, D; (2013) Antigenic variation in African trypanosomes: the importance of chromosomal and nuclear context in VSG expression control. Cellular microbiology, 15 (12). pp. 1984-93. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12215 Full text not available from this repository.

Gould, MK; Bachmaier, S; Ali, JA; Alsford, S; Tagoe, DN; Munday, JC; Schnaufer, AC; Horn, D; Boshart, M; de Koning, HP; (2013) Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA. Antimicrobial agents and chemotherapy, 57 (10). pp. 4882-93. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00508-13
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2012

Alsford, S; Dubois, K; Horn, D; Field, MC; (2012) Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes. Expert reviews in molecular medicine, 14. e13. ISSN 1462-3994 DOI: https://doi.org/10.1017/erm.2012.7 Full text not available from this repository.

Alsford, S; Eckert, S; Baker, N; Glover, L; Sanchez-Flores, A; Leung, KF; Turner, DJ; Field, MC; Berriman, M; Horn, D; (2012) High-throughput decoding of antitrypanosomal drug efficacy and resistance. Nature, 482 (7384). pp. 232-6. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature10771
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DuBois, KN; Alsford, S; Holden, JM; Buisson, J; Swiderski, M; Bart, JM; Ratushny, AV; Wan, Y; Bastin, P; Barry, JD; +5 more... Navarro, M; Horn, D; Aitchison, JD; Rout, MP; Field, MC; (2012) NUP-1 Is a Large Coiled-Coil Nucleoskeletal Protein in Trypanosomes with Lamin-Like Functions. PLoS biology, 10 (3). e1001287. ISSN 1544-9173 DOI: https://doi.org/10.1371/journal.pbio.1001287
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Field, MC; Horn, D; Alsford, S; Koreny, L; Rout, MP; (2012) Telomeres, tethers and trypanosomes. Nucleus (Austin, Tex), 3 (6). pp. 478-486. ISSN 1949-1034 DOI: https://doi.org/10.4161/nucl.22167
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2011

Alsford, S; Turner, DJ; Obado, SO; Sanchez-Flores, A; Glover, L; Berriman, M; Hertz-Fowler, C; Horn, D; (2011) High throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome. Genome research, 21 (6). pp. 915-24. ISSN 1088-9051 DOI: https://doi.org/10.1101/gr.115089.110
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2010

2009

2008

2007

2005

Alsford, S; Glover, L; Horn, D; (2005) Multiplex analysis of RNA interference defects in Trypanosoma brucei. Molecular and biochemical parasitology, 139 (1). pp. 129-32. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2004.11.001
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2004

Alsford, S; Horn, D; (2004) Trypanosomatid histones. Molecular microbiology, 53 (2). pp. 365-72. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2004.04151.x Full text not available from this repository.

2003

Alsford, NS; Navarro, M; Jamnadass, HR; Dunbar, H; Ackroyd, M; Murphy, NB; Gull, K; Ersfeld, K; (2003) The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei. Molecular microbiology, 47 (2). pp. 277-89. ISSN 0950-382X DOI: https://doi.org/10.1046/j.1365-2958.2003.03266.x Full text not available from this repository.

2001

Alsford, S; Wickstead, B; Ersfeld, K; Gull, K; (2001) Diversity and dynamics of the minichromosomal karyotype in Trypanosoma brucei. Molecular and biochemical parasitology, 113 (1). pp. 79-88. ISSN 0166-6851 DOI: https://doi.org/10.1016/S0166-6851(00)00388-1 Full text not available from this repository.

This list was generated on Wed Jun 26 07:45:39 2019 BST.