Items where Author or Contributor is "Kelly, John M"

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Number of items: 93.

2020

Mann, GS; (2020) Exploring the Potential of Vaccination to Combat Trypanosoma cruzi Infection using Bioluminescent Imaging. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04655803 Item availability may be restricted.
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2019

Foscolos, Angeliki-Sofia; Papanastasiou, Ioannis; Tsotinis, Andrew; Taylor, Martin C; Kelly, John M; (2019) Synthesis and Evaluation of Nifurtimox-Adamantane Adducts with Trypanocidal Activity. ChemMedChem, 14 (13). pp. 1227-1231. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.201900165
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Georgiadis, Markos-Orestis; Kourbeli, Violeta; Ioannidou, Vaya; Karakitsios, Evangelos; Papanastasiou, Ioannis; Tsotinis, Andrew; Komiotis, Dimitri; Vocat, Anthony; Cole, Stewart T; Taylor, Martin C; +1 more... Kelly, John M; (2019) Synthesis of diphenoxyadamantane alkylamines with pharmacological interest. Bioorganic & medicinal chemistry letters, 29 (11). pp. 1278-1281. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2019.04.010
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Rao, Srinivasa PS; Barrett, Michael P; Dranoff, Glenn; Faraday, Christopher J; Gimpelewicz, Claudio R; Hailu, Asrat; Jones, Catherine L; Kelly, John M; Lazdins-Helds, Janis K; Mäser, Pascal; +9 more... Mengel, Jose; Mottram, Jeremy C; Mowbray, Charles E; Sacks, David L; Scott, Phillip; Späth, Gerald F; Tarleton, Rick L; Spector, Jonathan M; Diagana, Thierry T; (2019) Drug Discovery for Kinetoplastid Diseases: Future Directions. ACS INFECTIOUS DISEASES, 5 (2). pp. 152-157. ISSN 2373-8227 DOI: https://doi.org/10.1021/acsinfecdis.8b00298
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2018

Adjogatse, Eyram; Erskine, Peter; Wells, Stephen A; Kelly, John M; Wilden, Jonathan D; Chan, AW Edith; Selwood, David; Coker, Alun; Wood, Steve; Cooper, Jonathan B; (2018) Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations. Acta crystallographica Section D, Structural biology, 74 (Pt 9). pp. 861-876. ISSN 2059-7983 DOI: https://doi.org/10.1107/S2059798318009208
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Bistrović, Andrea; Krstulović, Luka; Stolić, Ivana; Drenjančević, Domagoj; Talapko, Jasminka; Taylor, Martin C; Kelly, John M; Bajić, Miroslav; Raić-Malić, Silvana; (2018) Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA. Journal of enzyme inhibition and medicinal chemistry, 33 (1). pp. 1323-1334. ISSN 1475-6366 DOI: https://doi.org/10.1080/14756366.2018.1484733
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Ghashghaei, Ouldouz; Kielland, Nicola; Revés, Marc; Taylor, Martin C; Kelly, John M; Di Pietro, Ornella; Muñoz-Torrero, Diego; Pérez, Belén; Lavilla, Rodolfo; (2018) Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases. Molecules (Basel, Switzerland), 23 (1). p. 177. ISSN 1420-3049 DOI: https://doi.org/10.3390/molecules23010177
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2017

Brand, Stephen; Ko, Eun Jung; Viayna, Elisabet; Thompson, Stephen; Spinks, Daniel; Thomas, Michael; Sandberg, Lars; Francisco, Amanda F; Jayawardhana, Shiromani; Smith, Victoria C; +26 more... Jansen, Chimed; De Rycker, Manu; Thomas, John; MacLean, Lorna; Osuna-Cabello, Maria; Riley, Jennifer; Scullion, Paul; Stojanovski, Laste; Simeons, Frederick RC; Epemolu, Ola; Shishikura, Yoko; Crouch, Sabrinia D; Bakshi, Tania S; Nixon, Christopher J; Reid, Iain H; Hill, Alan P; Underwood, Tim Z; Hindley, Sean J; Robinson, Sharon A; Kelly, John M; Fiandor, Jose M; Wyatt, Paul G; Marco, Maria; Miles, Timothy J; Read, Kevin D; Gilbert, Ian H; (2017) Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi. Journal of medicinal chemistry, 60 (17). pp. 7284-7299. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.7b00463
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Zoidis, Grigoris; Tsotinis, Andrew; Tsatsaroni, Alexandra; Taylor, Martin C; Kelly, John M; Efstathiou, Antonia; Smirlis, Despina; Fytas, George; (2017) Lipophilic conformationally constrained spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acid analogues as trypanocidal and leishmanicidal agents: An extended SAR study. Chemical biology & drug design, 91 (2). pp. 408-421. ISSN 1747-0277 DOI: https://doi.org/10.1111/cbdd.13088
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2016

Francisco, Amanda Fortes; Jayawardhana, Shiromani; Lewis, Michael D; White, Karen L; Shackleford, David M; Chen, Gong; Saunders, Jessica; Osuna-Cabello, Maria; Read, Kevin D; Charman, Susan A; +2 more... Chatelain, Eric; Kelly, John M; (2016) Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage. Scientific reports, 6 (1). 35351-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep35351
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Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N−Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie, 128 (31). pp. 9140-9144. ISSN 0044-8249 DOI: https://doi.org/10.1002/ange.201604109
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Kishore, Kranti G; Ghashghaei, Ouldouz; Estarellas, Carolina; Mestre, M Mar; Monturiol, Cristina; Kielland, Nicola; Kelly, John M; Francisco, Amanda Fortes; Jayawardhana, Shiromani; Muñoz-Torrero, Diego; +4 more... Pérez, Belén; Luque, F Javier; Gámez-Montaño, Rocío; Lavilla, Rodolfo; (2016) Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds. Angewandte Chemie (International ed in English), 55 (31). pp. 8994-8998. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.201604109 Full text not available from this repository.

Sola, Irene; Artigas, Albert; Taylor, Martin C; Pérez-Areales, F Javier; Viayna, Elisabet; Clos, M Victòria; Pérez, Belén; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego; (2016) Synthesis and biological evaluation of N-cyanoalkyl-, N-aminoalkyl-, and N-guanidinoalkyl-substituted 4-aminoquinoline derivatives as potent, selective, brain permeable antitrypanosomal agents. Bioorganic & medicinal chemistry, 24 (21). pp. 5162-5171. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2016.08.036
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2015

Di Pietro, Ornella; Vicente-García, Esther; Taylor, Martin C; Berenguer, Diana; Viayna, Elisabet; Lanzoni, Anna; Sola, Irene; Sayago, Helena; Riera, Cristina; Fisa, Roser; +5 more... Clos, M Victòria; Pérez, Belén; Kelly, John M; Lavilla, Rodolfo; Muñoz-Torrero, Diego; (2015) Multicomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activity. European journal of medicinal chemistry, 105. pp. 120-137. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2015.10.007
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Sola, Irene; Castellà, Sílvia; Viayna, Elisabet; Galdeano, Carles; Taylor, Martin C; Gbedema, Stephen Y; Pérez, Belén; Clos, M Victòria; Jones, Deuan C; Fairlamb, Alan H; +3 more... Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego; (2015) Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity. Bioorganic & medicinal chemistry, 23 (16). pp. 5156-5167. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2015.01.031 Full text not available from this repository.

2014

Campos, Mônica CO; Leon, Leonor L; Taylor, Martin C; Kelly, John M; (2014) Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert. Molecular and biochemical parasitology, 193 (1). pp. 17-19. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2014.01.002
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Sola, Irene; Artigas, Albert; Taylor, Martin C; Gbedema, Stephen Y; Pérez, Belén; Clos, M Victòria; Wright, Colin W; Kelly, John M; Muñoz-Torrero, Diego; (2014) Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. Bioorganic & medicinal chemistry letters, 24 (23). pp. 5435-5438. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.10.025 Full text not available from this repository.

Taylor, Martin C; Kelly, John M; (2014) Optimizing bioluminescence imaging to study protozoan parasite infections. Trends in parasitology, 30 (4). pp. 161-162. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2014.01.006 Full text not available from this repository.

2013

Alsford, Sam; Kelly, John M; Baker, Nicola; Horn, David; (2013) Genetic dissection of drug resistance in trypanosomes. Parasitology, 140 (12). pp. 1478-1491. ISSN 0031-1820 DOI: https://doi.org/10.1017/S003118201300022X
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Koperniku, Ana; Papanastasiou, Ioannis; Foscolos, George B; Tsotinis, Andrew; Taylor, Martin C; Kelly, John M; (2013) Synthesis and trypanocidal action of new adamantane substituted imidazolines. MedChemComm, 4 (5). p. 856. ISSN 2040-2503 DOI: https://doi.org/10.1039/c3md00081h Full text not available from this repository.

Tsatsaroni, Alexandra; Zoidis, Grigoris; Zoumpoulakis, Panagiotis; Tsotinis, Andrew; Taylor, Martin C; Kelly, John M; Fytas, George; (2013) An E/Z conformational behaviour study on the trypanocidal action of lipophilic spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acids. Tetrahedron letters, 54 (25). pp. 3238-3240. ISSN 0040-4039 DOI: https://doi.org/10.1016/j.tetlet.2013.03.128
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2012

Kelly, John M; Taylor, Martin C; Horn, David; Loza, Einars; Kalvinsh, Ivars; Björkling, Fredrik; (2012) Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei. Bioorganic & medicinal chemistry letters, 22 (5). pp. 1886-1890. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.01.072
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Mejia, Ana Maria; Hall, Belinda S; Taylor, Martin C; Gómez-Palacio, Andrés; Wilkinson, Shane R; Triana-Chávez, Omar; Kelly, John M; (2012) Benznidazole-resistance in Trypanosoma cruzi is a readily acquired trait that can arise independently in a single population. The Journal of infectious diseases, 206 (2). pp. 220-228. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jis331
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Torres, Eva; Duque, María D; López-Querol, Marta; Taylor, Martin C; Naesens, Lieve; Ma, Chunlong; Pinto, Lawrence H; Sureda, Francesc X; Kelly, John M; Vázquez, Santiago; (2012) Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities. Bioorganic & medicinal chemistry, 20 (2). pp. 942-948. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2011.11.050 Full text not available from this repository.

2011

Defaux, Julien; Sala, Marta; Formosa, Xavier; Galdeano, Carles; Taylor, Martin C; Alobaid, Waleed AA; Kelly, John M; Wright, Colin W; Camps, Pelayo; Muñoz-Torrero, Diego; (2011) Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. Bioorganic & medicinal chemistry, 19 (5). pp. 1702-1707. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2011.01.028
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Fytas, Christos; Zoidis, Grigoris; Tzoutzas, Nikolaos; Taylor, Martin C; Fytas, George; Kelly, John M; (2011) Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity. Journal of medicinal chemistry, 54 (14). pp. 5250-5254. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm200217m
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Obado, Samson O; Bot, Christopher; Echeverry, Maria C; Bayona, Julio C; Alvarez, Vanina E; Taylor, Martin C; Kelly, John M; (2011) Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei. Nucleic acids research, 39 (3). pp. 1023-1033. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gkq839
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Taylor, Martin C; Huang, Huan; Kelly, John M; (2011) Genetic techniques in Trypanosoma cruzi. Advances in parasitology, 75. pp. 231-250. ISSN 0065-308X DOI: https://doi.org/10.1016/B978-0-12-385863-4.00011-3 Full text not available from this repository.

Wilkinson, Shane R; Bot, Christopher; Kelly, John M; Hall, Belinda S; (2011) Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives. Current topics in medicinal chemistry, 11 (16). pp. 2072-2084. ISSN 1568-0266 DOI: https://doi.org/10.2174/156802611796575894 Full text not available from this repository.

2010

Duque, María D; Camps, Pelayo; Torres, Eva; Valverde, Elena; Sureda, Francesc X; López-Querol, Marta; Camins, Antoni; Prathalingam, S Radhika; Kelly, John M; Vázquez, Santiago; (2010) New oxapolycyclic cage amines with NMDA receptor antagonist and trypanocidal activities. Bioorganic & medicinal chemistry, 18 (1). pp. 46-57. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2009.11.017 Full text not available from this repository.

Patel, Shreenal; Hussain, Syeed; Harris, Richard; Sardiwal, Sunita; Kelly, John M; Wilkinson, Shane R; Driscoll, Paul C; Djordjevic, Snezana; (2010) Structural insights into the catalytic mechanism of Trypanosoma cruzi GPXI (glutathione peroxidase-like enzyme I). The Biochemical journal, 425 (3). pp. 513-522. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20091167 Full text not available from this repository.

Zoidis, Grigoris; Kolocouris, Nicolas; Kelly, John M; Prathalingam, S Radhika; Naesens, Lieve; De Clercq, Erik; (2010) Design and synthesis of bioactive adamantanaminoalcohols and adamantanamines. European journal of medicinal chemistry, 45 (11). pp. 5022-5030. ISSN 0223-5234 DOI: https://doi.org/10.1016/j.ejmech.2010.08.009 Full text not available from this repository.

2009

Duque, María D; Camps, Pelayo; Profire, Lenuta; Montaner, Silvia; Vázquez, Santiago; Sureda, Francesc X; Mallol, Jordi; López-Querol, Marta; Naesens, Lieve; De Clercq, Erik; +2 more... Prathalingam, S Radhika; Kelly, John M; (2009) Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines. Bioorganic & medicinal chemistry, 17 (8). pp. 3198-3206. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2009.02.007 Full text not available from this repository.

Papanastasiou, Ioannis; Tsotinis, Andrew; Zoidis, Grigoris; Kolocouris, Nicolas; Prathalingam, S Radhika; Kelly, John M; (2009) Design and synthesis of Trypanosoma brucei active 1-alkyloxy and 1-benzyloxyadamantano 2-guanylhydrazones. ChemMedChem, 4 (7). pp. 1059-1062. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.200900019 Full text not available from this repository.

Wilkinson, Shane R; Kelly, John M; (2009) Trypanocidal drugs: mechanisms, resistance and new targets. Expert reviews in molecular medicine, 11. e31-. ISSN 1462-3994 DOI: https://doi.org/10.1017/S1462399409001252 Full text not available from this repository.

2008

Camps, Pelayo; Duque, María D; Vázquez, Santiago; Naesens, Lieve; De Clercq, Erik; Sureda, Francesc X; López-Querol, Marta; Camins, Antoni; Pallàs, Mercè; Prathalingam, S Radhika; +4 more... Kelly, John M; Romero, Vanessa; Ivorra, Dolores; Cortés, Diego; (2008) Synthesis and pharmacological evaluation of several ring-contracted amantadine analogs. Bioorganic & medicinal chemistry, 16 (23). pp. 9925-9936. ISSN 0968-0896 DOI: https://doi.org/10.1016/j.bmc.2008.10.028 Full text not available from this repository.

Papanastasiou, Ioannis; Tsotinis, Andrew; Foscolos, George B; Prathalingam, S Radhika; Kelly, John M; (2008) Synthesis of conformationally constrained adamantane imidazolines with trypanocidal activity. Journal of heterocyclic chemistry, 45 (5). pp. 1401-1406. ISSN 0022-152X DOI: https://doi.org/10.1002/jhet.5570450524 Full text not available from this repository.

Papanastasiou, Ioannis; Tsotinis, Andrew; Kolocouris, Nicolas; Prathalingam, S Radhika; Kelly, John M; (2008) Design, synthesis, and trypanocidal activity of new aminoadamantane derivatives. Journal of medicinal chemistry, 51 (5). pp. 1496-1500. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm7014292 Full text not available from this repository.

Piacenza, Lucía; Peluffo, Gonzalo; Alvarez, María Noel; Kelly, John M; Wilkinson, Shane R; Radi, Rafael; (2008) Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite. The Biochemical journal, 410 (2). pp. 359-368. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20071138 Full text not available from this repository.

Taylor, Martin C; Kaur, Harparkash; Blessington, Bernard; Kelly, John M; Wilkinson, Shane R; (2008) Validation of spermidine synthase as a drug target in African trypanosomes. The Biochemical journal, 409 (2). pp. 563-569. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20071185 Full text not available from this repository.

Wilkinson, Shane R; Taylor, Martin C; Horn, David; Kelly, John M; Cheeseman, Ian; (2008) A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes. Proceedings of the National Academy of Sciences of the United States of America, 105 (13). pp. 5022-5027. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0711014105 Full text not available from this repository.

Zoidis, Grigoris; Tsotinis, Andrew; Kolocouris, Nicolas; Kelly, John M; Prathalingam, S Radhika; Naesens, Lieve; De Clercq, Erik; (2008) Design and synthesis of bioactive 1,2-annulated adamantane derivatives. Organic & biomolecular chemistry, 6 (17). pp. 3177-3185. ISSN 1477-0520 DOI: https://doi.org/10.1039/b804907f Full text not available from this repository.

2007

Kolocouris, Nicolas; Zoidis, Grigoris; Foscolos, George B; Fytas, George; Prathalingham, S Radhika; Kelly, John M; Naesens, Lieve; De Clercq, Erik; (2007) Design and synthesis of bioactive adamantane spiro heterocycles. Bioorganic & medicinal chemistry letters, 17 (15). pp. 4358-4362. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2007.04.108 Full text not available from this repository.

Logan, Flora J; Taylor, Martin C; Wilkinson, Shane R; Kaur, Harparkash; Kelly, John M; (2007) The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase. The Biochemical journal, 407 (3). pp. 419-426. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20070766 Full text not available from this repository.

Obado, Samson O; Bot, Christopher; Nilsson, Daniel; Andersson, Bjorn; Kelly, John M; (2007) Repetitive DNA is associated with centromeric domains in Trypanosoma brucei but not Trypanosoma cruzi. Genome biology, 8 (3). R37-. ISSN 1465-6906 DOI: https://doi.org/10.1186/gb-2007-8-3-r37
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Piacenza, Lucía; Irigoín, Florencia; Alvarez, María Noel; Peluffo, Gonzalo; Taylor, Martin C; Kelly, John M; Wilkinson, Shane R; Radi, Rafael; (2007) Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression. The Biochemical journal, 403 (2). pp. 323-334. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20061281 Full text not available from this repository.

Prathalingham, S Radhika; Wilkinson, Shane R; Horn, David; Kelly, John M; (2007) Deletion of the Trypanosoma brucei superoxide dismutase gene sodb1 increases sensitivity to nifurtimox and benznidazole. Antimicrobial agents and chemotherapy, 51 (2). pp. 755-758. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01360-06 Full text not available from this repository.

Prathalingham, SR; Wilkinson, SR; Horn, D; Kelly, JM; (2007) Deletion of the Trypanosoma brucei superoxide dismutase gene sodb1 increases sensitivity to nifurtimox and benznidazole. Antimicrobial agents and chemotherapy, 51 (2). pp. 755-758. ISSN 0066-4804 DOI: https://doi.org/10.1128/aac.01360-06 Full text not available from this repository.

Renauld, H; Kelly, JM; Horn, D; (2007) Chromosome structure and dynamics. In: Barry, D; Mottram, J; McCulloch, R; Acosta-Serrano, A; Renauld, H, (eds.) Trypanosomes - After the Genome. Horizon Scientific Press, Norwich, UK., pp. 91-132. https://researchonline.lshtm.ac.uk/id/eprint/11566 Full text not available from this repository.

2006

Kelly, John M; McRobert, Louisa; Baker, David A; (2006) Evidence on the chromosomal location of centromeric DNA in Plasmodium falciparum from etoposide-mediated topoisomerase-II cleavage. Proceedings of the National Academy of Sciences of the United States of America, 103 (17). pp. 6706-6711. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0510363103 Full text not available from this repository.

MacRae, James I; Obado, Samson O; Turnock, Daniel C; Roper, Janine R; Kierans, Martin; Kelly, John M; Ferguson, Michael AJ; (2006) The suppression of galactose metabolism in Trypanosoma cruzi epimastigotes causes changes in cell surface molecular architecture and cell morphology. Molecular and biochemical parasitology, 147 (1). pp. 126-136. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2006.02.011 Full text not available from this repository.

Wilkinson, Shane R; Prathalingam, S Radhika; Taylor, Martin C; Ahmed, Aiyaz; Horn, David; Kelly, John M; (2006) Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei. Free radical biology & medicine, 40 (2). pp. 198-209. ISSN 0891-5849 DOI: https://doi.org/10.1016/j.freeradbiomed.2005.06.022 Full text not available from this repository.

2005

Gluenz, E; (2005) Developmentally regulated genes in Trypansoma Cruzi. PhD thesis, London School of Hygiene and Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04654693
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Kelly, JM; Taylor, MC; Wilkinson, SR; (2005) Trypanosoma cruzi. In: Fuchs, J; Podda, M; Goethe, JW, (eds.) Encyclopedia of Diagnostic Genomics and Proteomics. Marcel Dekker, Inc., New York, USA, pp. 1297-1301. https://researchonline.lshtm.ac.uk/id/eprint/15644 Full text not available from this repository.

Wilkinson, Shane R; Prathalingam, S Radhika; Taylor, Martin C; Horn, David; Kelly, John M; (2005) Vitamin C biosynthesis in trypanosomes: a role for the glycosome. Proceedings of the National Academy of Sciences of the United States of America, 102 (33). pp. 11645-11650. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.0504251102 Full text not available from this repository.

2004

Baker, David A; Kelly, John M; (2004) Structure, function and evolution of microbial adenylyl and guanylyl cyclases. Molecular microbiology, 52 (5). pp. 1229-1242. ISSN 0950-382X DOI: https://doi.org/10.1111/j.1365-2958.2004.04067.x Full text not available from this repository.

Baker, David A; Kelly, John M; (2004) Purine nucleotide cyclases in the malaria parasite. Trends in parasitology, 20 (5). pp. 227-232. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2004.02.007 Full text not available from this repository.

Bromley, Elizabeth V; Taylor, Martin C; Wilkinson, Shane R; Kelly, John M; (2004) The amino terminal domain of a novel WD repeat protein from Trypanosoma cruzi contains a non-canonical mitochondrial targeting signal. International journal for parasitology, 34 (1). pp. 63-71. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2003.09.004 Full text not available from this repository.

2003

Kelly, JM; (2003) Molecular Mechanisms in the Pathogenesis of Chagas? Disease. Landes Bioscience, Georgetown, Texas, USA. https://researchonline.lshtm.ac.uk/id/eprint/15543 Full text not available from this repository.

Muhia, David K; Swales, Claire A; Eckstein-Ludwig, Ursula; Saran, Shweta; Polley, Spencer D; Kelly, John M; Schaap, Pauline; Krishna, Sanjeev; Baker, David A; (2003) Multiple splice variants encode a novel adenylyl cyclase of possible plastid origin expressed in the sexual stage of the malaria parasite Plasmodium falciparum. The Journal of biological chemistry, 278 (24). pp. 22014-22022. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M301639200 Full text not available from this repository.

Wilkinson, SR; Kelly, JM; (2003) How does Trypanosoma cruzi survive the toxic effects of reactive oxygen species? In: Kelly, JM, (ed.) Molecular Mechanisms in the Pathogenesis of Chagas? Disease. Landes Bioscience, Georgetown, Texas, USA, pp. 56-71. https://researchonline.lshtm.ac.uk/id/eprint/15542 Full text not available from this repository.

Wilkinson, Shane R; Horn, David; Prathalingam, S Radhika; Kelly, John M; (2003) RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome. The Journal of biological chemistry, 278 (34). pp. 31640-31646. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M303035200 Full text not available from this repository.

Wilkinson, Shane R; Kelly, John M; (2003) The role of glutathione peroxidases in trypanosomatids. Biological chemistry, 384 (4). pp. 517-525. ISSN 1431-6730 DOI: https://doi.org/10.1515/BC.2003.060 Full text not available from this repository.

2002

Kelly, JM; Obado, S; (2002) Chromosome fragmentation as an approach to whole-genome analysis in trypanosomes. In: Wren, BW; Dorrell, N, (eds.) Functional Microbial Genomics. Academic Press Inc, San Diego, pp. 397-406. https://researchonline.lshtm.ac.uk/id/eprint/16484 Full text not available from this repository.

Ruben, L; Kelly, JM; Chakrabarti, D; (2002) Intracellular signalling. In: Koumuniecki, R; Nilsen, T; Marr, JJ, (eds.) Molecular Medical Parasitology. Academic Press, London, pp. 241-276. https://researchonline.lshtm.ac.uk/id/eprint/15541 Full text not available from this repository.

Taylor, MC; Kelly, JM; (2002) Functional dissection of the Trypanosoma cruzi genome: New approaches in a new era. In: Tyler, K; Miles, MA, (eds.) American Trypanosomiasis. Kluwer Academic Publishers, London, pp. 57-68. https://researchonline.lshtm.ac.uk/id/eprint/15544 Full text not available from this repository.

Wilkinson, Shane R; Meyer, David J; Taylor, Martin C; Bromley, Elizabeth V; Miles, Michael A; Kelly, John M; (2002) The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. The Journal of biological chemistry, 277 (19). pp. 17062-17071. ISSN 0021-9258 DOI: https://doi.org/10.1074/jbc.M111126200 Full text not available from this repository.

Wilkinson, Shane R; Obado, Samson O; Mauricio, Isabel L; Kelly, John M; (2002) Trypanosoma cruzi expresses a plant-like ascorbate-dependent hemoperoxidase localized to the endoplasmic reticulum. Proceedings of the National Academy of Sciences of the United States of America, 99 (21). pp. 13453-13458. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.202422899 Full text not available from this repository.

Wilkinson, Shane R; Taylor, Martin C; Touitha, Said; Mauricio, Isabel L; Meyer, David J; Kelly, John M; (2002) TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum. The Biochemical journal, 364 (Pt 3). pp. 787-794. ISSN 0264-6021 DOI: https://doi.org/10.1042/BJ20020038 Full text not available from this repository.

2001

Allen, CL; Kelly, JM; (2001) Trypanosoma cruzi: mucin pseudogenes organized in a tandem array. Experimental parasitology, 97 (3). pp. 173-177. ISSN 0014-4894 DOI: https://doi.org/10.1006/expr.2001.4600 Full text not available from this repository.

Kelly, JM; Quack, G; Miles, MM; (2001) In vitro and in vivo activities of aminoadamantane and aminoalkylcyclohexane derivatives against Trypanosoma brucei. Antimicrobial agents and chemotherapy, 45 (5). pp. 1360-1366. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.45.5.1360-1366.2001 Full text not available from this repository.

This list was generated on Fri Aug 14 06:14:42 2020 BST.