Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February.
Grint, DJ
; Wing, K
; Williamson, E
; McDonald, HI
; Bhaskaran, K
; Evans, D; Evans, SJ
; Walker, AJ; Hickman, G; Nightingale, E
; +26 more...Schultze, A
; Rentsch, CT
; Bates, C; Cockburn, J; Curtis, HJ; Morton, CE; Bacon, S; Davy, S; Wong, AY
; Mehrkar, A; Tomlinson, L
; Douglas, IJ
; Mathur, R
; Blomquist, P; MacKenna, B; Ingelsby, P; Croker, R; Parry, J; Hester, F; Harper, S; DeVito, NJ; Hulme, W; Tazare, J
; Goldacre, B
; Smeeth, L
; Eggo, RM
and
(2021)
Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February.
Eurosurveillance, 26 (11).
pp. 10-15.
ISSN 1025-7917
DOI: 10.2807/1560-7917.ES.2021.26.11.2100256
The SARS-CoV-2 B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. We found increased risk of death for VOC compared with non-VOC cases in England (hazard ratio: 1.67; 95% confidence interval: 1.34-2.09; p < 0.0001). Absolute risk of death by 28 days increased with age and comorbidities. This VOC has potential to spread faster with higher mortality than the pandemic to date.
Item Type | Article |
---|---|
Elements ID | 158158 |
Date Deposited | 20 Apr 2021 10:46 |
Explore Further
- Grint, Daniel
- Wing, K
- Williamson, E
- McDonald, Helen
- Bhaskaran, K
- Evans, S
- Nightingale, Emily S
- Schultze, Anna
- Rentsch, Christopher
- Wong, Angel YS
- Tomlinson, Laurie A
- Douglas, I
- Mathur, Rohini
- Tazare, John
- Goldacre, Ben
- Smeeth, L
- Eggo, RM
- Dept of Infectious Disease Epidemiology & International Health (2023-)
- Dept of Non-Communicable Disease Epidemiology
- Dept of Medical Statistics
- Dept of Infectious Disease Epidemiology (-2023)
- Dept of Infectious Disease Epidemiology & Dynamics (2023-)
- Directorate
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