Bidulka, Patrick; Lugo-Palacios, David G; Carroll, Orlagh; O'Neill, Stephen; Adler, Amanda I; Basu, Anirban; Silverwood, Richard J; Bartlett, Jonathan W; Nitsch, Dorothea; Charlton, Paul; +5 more... Briggs, Andrew H; Smeeth, Liam; Douglas, Ian J; Khunti, Kamlesh; Grieve, Richard; (2024) Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data. BMJ, 385. e077097-. DOI: https://doi.org/10.1136/bmj-2023-077097

Brown, Jeremy P; Hunnicutt, Jacob N; Ali, M Sanni; Bhaskaran, Krishnan; Cole, Ashley; Langan, Sinead M; Nitsch, Dorothea; Rentsch, Christopher T; Galwey, Nicholas W; Wing, Kevin; +1 more... Douglas, Ian J; (2024) Quantifying possible bias in clinical and epidemiological studies with quantitative bias analysis: common approaches and limitations. BMJ, 385. e076365-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj-2023-076365

Coste, Astrid; Wong, Angel Ys; Warren-Gash, Charlotte; Matthewman, Julian; Bate, Andrew; Douglas, Ian J; (2024) Implementation of a Taxonomy-Based Framework for the Selection of Appropriate Drugs and Outcomes for Real-World Data Signal Detection Studies. Drug safety, 47 (2). pp. 183-192. ISSN 0114-5916 DOI: https://doi.org/10.1007/s40264-023-01382-5

Dedman, Daniel; Williams, Rachael; Bhaskaran, Krishnan; Douglas, Ian J; (2024) Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases. BMJ open, 14 (2). e070258-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2022-070258

Douglas, Ian J; Peh, Jerlyn; Mansfield, Kathryn E; Trelfa, Anna; Fowler, Tom; Boulter, Matthew; Cleary, Paul; Smith, Jenifer; Edmunds, W John; (2024) A self-controlled case series study to measure the risk of SARS-CoV-2 infection associated with attendance at sporting and cultural events: the UK Events Research Programme events. BMC medicine, 22 (1). 100-. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-024-03276-4

Schultze, Anna; Martin, Ivonne; Messina, Davide; Bots, Sophie; Belitser, Svetlana; José Carreras-Martínez, Juan; Correcher-Martinez, Elisa; Urchueguía-Fornes, Arantxa; Martín-Pérez, Mar; García-Poza, Patricia; +11 more... Villalobos, Felipe; Pallejà-Millán, Meritxell; Alberto Bissacco, Carlo; Segundo, Elena; Souverein, Patrick; Riefolo, Fabio; Durán, Carlos E; Gini, Rosa; Sturkenboom, Miriam; Klungel, Olaf; Douglas, Ian; (2024) A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases. Vaccine, 42 (12). pp. 3039-3048. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2024.03.043

Baptiste, PJ; (2023) Real-world effectiveness and adverse events caused by ACE inhibitors and ARBs for reduction in cardiovascular events with validation against the ONTARGET trial. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04671559

Brown, JP; (2023) Application of methods for handling unmeasured confounding in pharmacoepidemiological studies. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04671281 Item availability may be restricted.

Brown, Jeremy P; Wing, Kevin; Leyrat, Clémence; Evans, Stephen J; Mansfield, Kathryn E; Wong, Angel YS; Smeeth, Liam; Galwey, Nicholas W; Douglas, Ian J; (2023) Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection. JAMA cardiology, 8 (9). pp. 865-870. ISSN 2380-6583 DOI: https://doi.org/10.1001/jamacardio.2023.2418

Green, Amelia CA; Curtis, Helen J; Higgins, Rose; Nab, Linda; Mahalingasivam, Viyaasan; Smith, Rebecca M; Mehrkar, Amir; Inglesby, Peter; Drysdale, Henry; DeVito, Nicholas J; +32 more... Croker, Richard; Rentsch, Christopher T; Bhaskaran, Krishnan; Tazare, John; Zheng, Bang; Andrews, Colm D; Bacon, Sebastian CJ; Davy, Simon; Dillingham, Iain; Evans, David; Fisher, Louis; Hickman, George; Hopcroft, Lisa EM; Hulme, William J; Massey, Jon; MacDonald, Orla; Morley, Jessica; Morton, Caroline E; Park, Robin Y; Walker, Alex J; Ward, Tom; Wiedemann, Milan; Bates, Christopher; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Goldacre, Ben; Tomlinson, Laurie A; MacKenna, Brian; (2023) Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY. BMJ Medicine, 2 (1). e000276-. ISSN 2754-0413 DOI: https://doi.org/10.1136/bmjmed-2022-000276

Tazare, John; Gibbons, Daniel C; Bokern, Marleen; Williamson, Elizabeth J; Gillespie, Iain A; Cunnington, Marianne; Logie, John; Douglas, Ian J; (2023) Prevalent new user designs: A literature review of current implementation practice. Pharmacoepidemiology and drug safety, 32 (11). pp. 1252-1260. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.5656

Zheng, Bang; Campbell, Jacqueline; Carr, Edward J; Tazare, John; Nab, Linda; Mahalingasivam, Viyaasan; Mehrkar, Amir; Santhakumaran, Shalini; Steenkamp, Retha; Loud, Fiona; +15 more... Lyon, Susan; Scanlon, Miranda; Hulme, William J; Green, Amelia CA; Curtis, Helen J; Fisher, Louis; Parker, Edward; Goldacre, Ben; Douglas, Ian; Evans, Stephen; MacKenna, Brian; Bell, Samira; Tomlinson, Laurie A; Nitsch, Dorothea; OpenSAFELY Collaborative and LH&W NCS (or CONVALESCENCE) Collabo; (2023) Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases. Clinical kidney journal, 16 (11). pp. 2048-2058. ISSN 2048-8505 DOI: https://doi.org/10.1093/ckj/sfad184

Zheng, Bang; Tazare, John; Nab, Linda; Green, Amelia Ca; Curtis, Helen J; Mahalingasivam, Viyaasan; Herrett, Emily L; Costello, Ruth E; Eggo, Rosalind M; Speed, Victoria; +15 more... Bacon, Sebastian Cj; Bates, Christopher; Parry, John; Cockburn, Jonathan; Hester, Frank; Harper, Sam; Schaffer, Andrea L; Hulme, William J; Mehrkar, Amir; Evans, Stephen Jw; MacKenna, Brian; Goldacre, Ben; Douglas, Ian J; Tomlinson, Laurie A; OpenSAFELY Collaborative; (2023) Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform. The Lancet Regional Health - Europe, 34. 100741-. DOI: https://doi.org/10.1016/j.lanepe.2023.100741

Bhaskaran, Krishnan; Rentsch, Christopher T; Hickman, George; Hulme, William J; Schultze, Anna; Curtis, Helen J; Wing, Kevin; Warren-Gash, Charlotte; Tomlinson, Laurie; Bates, Chris J; +22 more... Mathur, Rohini; MacKenna, Brian; Mahalingasivam, Viyaasan; Wong, Angel; Walker, Alex J; Morton, Caroline E; Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Bacon, Sebastian; Smeeth, Liam; Goldacre, Ben; (2022) Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform. PLoS medicine, 19 (1). e1003871-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1003871

Bidulka, Patrick; Mathur, Rohini; Lugo-Palacios, David G; O'Neill, Stephen; Basu, Anirban; Silverwood, Richard J; Charlton, Paul; Briggs, Andrew; Smeeth, Liam; Adler, Amanda I; +3 more... Douglas, Ian J; Khunti, Kamlesh; Grieve, Richard; (2022) Ethnic and socioeconomic disparities in initiation of second-line antidiabetic treatment for people with type 2 diabetes in England: A cross-sectional study. Diabetes, obesity & metabolism, 25 (1). pp. 282-292. ISSN 1462-8902 DOI: https://doi.org/10.1111/dom.14874

Bots, Sophie H; Riera-Arnau, Judit; Belitser, Svetlana V; Messina, Davide; Aragón, Maria; Alsina, Ema; Douglas, Ian J; Durán, Carlos E; García-Poza, Patricia; Gini, Rosa; +14 more... Herings, Ron MC; Huerta, Consuelo; Sisay, Malede Mequanent; Martín-Pérez, Mar; Martin, Ivonne; Overbeek, Jetty A; Paoletti, Olga; Pallejà-Millán, Meritxell; Schultze, Anna; Souverein, Patrick; Swart, Karin MA; Villalobos, Felipe; Klungel, Olaf H; Sturkenboom, Miriam CJM; (2022) Myocarditis and pericarditis associated with SARS-CoV-2 vaccines: A population-based descriptive cohort and a nested self-controlled risk interval study using electronic health care data from four European countries. Frontiers in pharmacology, 13. 1038043-. ISSN 1663-9812 DOI: https://doi.org/10.3389/fphar.2022.1038043

Chui, Celine SL; Cheung, Ka Shing; Brown, Jeremy P; Douglas, Ian J; Wong, Ian CK; Chan, Esther W; Wong, Angel YS; (2022) Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series. International journal of epidemiology, 52 (3). pp. 899-907. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyac196

Coste, Astrid; Wong, Angel; Bokern, Marleen; Bate, Andrew; Douglas, Ian J; (2022) Methods for drug safety signal detection using routinely collected observational electronic health care data: A systematic review. Pharmacoepidemiology and drug safety, 32 (1). pp. 28-43. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.5548

Curtis, Helen J; Inglesby, Peter; MacKenna, Brian; Croker, Richard; Hulme, William J; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Morton, Caroline E; Bacon, Sebastian Cj; +27 more... Smith, Rebecca M; Evans, David; Mehrkar, Amir; Tomlinson, Laurie; Walker, Alex J; Bates, Christopher; Hickman, George; Ward, Tom; Morley, Jessica; Cockburn, Jonathan; Davy, Simon; Williamson, Elizabeth J; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben; (2022) Recording of 'COVID-19 vaccine declined': a cohort study on 57.9 million National Health Service patients' records in situ using OpenSAFELY, England, 8 December 2020 to 25 May 2021. Eurosurveillance, 27 (33). ISSN 1560-7917 DOI: https://doi.org/10.2807/1560-7917.ES.2022.27.33.2100885

Davidson, Jennifer A; Banerjee, Amitava; Douglas, Ian; Leyrat, Clémence; Pebody, Richard; McDonald, Helen I; Herrett, Emily; Forbes, Harriet; Smeeth, Liam; Warren-Gash, Charlotte; (2022) Primary prevention of acute cardiovascular events by influenza vaccination: an observational study. European heart journal, 44 (7). pp. 610-620. ISSN 0195-668X DOI: https://doi.org/10.1093/eurheartj/ehac737

Hulme, William J; Williamson, Elizabeth J; Green, Amelia CA; Bhaskaran, Krishnan; McDonald, Helen I; Rentsch, Christopher T; Schultze, Anna; Tazare, John; Curtis, Helen J; Walker, Alex J; +32 more... Tomlinson, Laurie A; Palmer, Tom; Horne, Elsie MF; MacKenna, Brian; Morton, Caroline E; Mehrkar, Amir; Morley, Jessica; Fisher, Louis; Bacon, Sebastian CJ; Evans, David; Inglesby, Peter; Hickman, George; Davy, Simon; Ward, Tom; Croker, Richard; Eggo, Rosalind M; Wong, Angel YS; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Grint, Daniel J; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Sterne, Jonathan AC; Hernán, Miguel A; Goldacre, Ben; (2022) Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY. BMJ, 378. e068946-. DOI: https://doi.org/10.1136/bmj-2021-068946

MacKenna, Brian; Kennedy, Nicholas A; Mehrkar, Amir; Rowan, Anna; Galloway, James; Matthewman, Julian; Mansfield, Kathryn E; Bechman, Katie; Yates, Mark; Brown, Jeremy; +38 more... Schultze, Anna; Norton, Sam; Walker, Alex J; Morton, Caroline E; Harrison, David; Bhaskaran, Krishnan; Rentsch, Christopher T; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hickman, George; Ward, Tom; Davy, Simon; Green, Amelia; Fisher, Louis; Hulme, William; Bates, Chris; Curtis, Helen J; Tazare, John; Eggo, Rosalind M; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie A; Mathur, Rohini; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Lees, Charlie W; Evans, Stephen JW; Goldacre, Ben; Smith, Catherine H; Langan, Sinéad M; (2022) Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform. The Lancet Rheumatology, 4 (7). e490-e506. ISSN 2665-9913 DOI: https://doi.org/10.1016/S2665-9913(22)00098-4

OpenSAFELY Collaborative; Green, Amelia; Curtis, Helen; Hulme, William; Williamson, Elizabeth; McDonald, Helen; Bhaskaran, Krishnan; Rentsch, Christopher; Schultze, Anna; MacKenna, Brian; +32 more... Mahalingasivam, Viyaasan; Tomlinson, Laurie; Walker, Alex; Fisher, Louis; Massey, Jon; Andrews, Colm; Hopcroft, Lisa; Morton, Caroline; Croker, Richard; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; Evans, David; Inglesby, Peter; Hickman, George; Ward, Tom; Davy, Simon; Mathur, Rohini; Tazare, John; Eggo, Rosalind; Wing, Kevin; Wong, Angel; Forbes, Harriet; Bates, Chris; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Evans, Stephen; Smeeth, Liam; Goldacre, Ben; (2022) Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY. BMC medicine, 20 (1). 243-. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-022-02422-0

OpenSAFELY Collaborative; Tazare, John; Walker, Alex J; Tomlinson, Laurie A; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; +31 more... Mathur, Rohini; Wong, Angel Ys; Schultze, Anna; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; Davy, Simon; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Warren-Gash, Charlotte; Bhate, Ketaki; Nitsch, Dorothea; Powell, Emma; Mulick, Amy; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen Jw; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; (2022) Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform. Wellcome open research, 7. 142-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.17735.1

Schultze, Anna; Nightingale, Emily; Evans, David; Hulme, William; Rosello, Alicia; Bates, Chris; Cockburn, Jonathan; MacKenna, Brian; Curtis, Helen J; Morton, Caroline E; +32 more... Croker, Richard; Bacon, Seb; McDonald, Helen I; Rentsch, Christopher T; Bhaskaran, Krishnan; Mathur, Rohini; Tomlinson, Laurie A; Williamson, Elizabeth J; Forbes, Harriet; Tazare, John; Grint, Daniel; Walker, Alex J; Inglesby, Peter; DeVito, Nicholas J; Mehrkar, Amir; Hickman, George; Davy, Simon; Ward, Tom; Fisher, Louis; Green, Amelia Ca; Wing, Kevin; Wong, Angel Ys; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Eggo, Rosalind M; Goldacre, Ben; Leon, David A; (2022) Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65. The Lancet regional health. Europe, 14. 100295-. ISSN 2666-7762 DOI: https://doi.org/10.1016/j.lanepe.2021.100295

Tazare, JR; (2022) High-dimensional propensity scores for data-driven confounder adjustment in UK electronic health records. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04664727

Walker, Jemma L; Schultze, Anna; Tazare, John; Tamborska, Arina; Singh, Bhagteshwar; Donegan, Katherine; Stowe, Julia; Morton, Caroline E; Hulme, William J; Curtis, Helen J; +27 more... Williamson, Elizabeth J; Mehrkar, Amir; Eggo, Rosalind M; Rentsch, Christopher T; Mathur, Rohini; Bacon, Sebastian; Walker, Alex J; Davy, Simon; Evans, David; Inglesby, Peter; Hickman, George; MacKenna, Brian; Tomlinson, Laurie; Ca Green, Amelia; Fisher, Louis; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Bates, Christopher; Evans, Stephen Jw; Solomon, Tom; Andrews, Nick J; Douglas, Ian J; Goldacre, Ben; Smeeth, Liam; McDonald, Helen I; (2022) Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform. Vaccine, 40 (32). pp. 4479-4487. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2022.06.010

Wing, Kevin; Grint, Daniel J; Mathur, Rohini; Gibbs, Hamish P; Hickman, George; Nightingale, Emily; Schultze, Anna; Forbes, Harriet; Nafilyan, Vahé; Bhaskaran, Krishnan; +16 more... Williamson, Elizabeth; House, Thomas; Pellis, Lorenzo; Herrett, Emily; Gautam, Nileesa; Curtis, Helen J; Rentsch, Christopher T; Wong, Angel YS; MacKenna, Brian; Mehrkar, Amir; Bacon, Seb; Douglas, Ian J; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; Eggo, Rosalind M; (2022) Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform. International Journal of Epidemiology, 51 (6). pp. 1745-1760. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyac158

Wong, Angel Ys; Tomlinson, Laurie; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; MacKenna, Brian; +21 more... Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J; (The OpenSAFELY Collaborative); (2022) Association between oral anticoagulants and COVID-19-related outcomes: a population-based cohort study. The British journal of general practice : the journal of the Royal College of General Practitioners, 72 (720). e456-e463. ISSN 0960-1643 DOI: https://doi.org/10.3399/BJGP.2021.0689

Zheng, Bang; Green, Amelia CA; Tazare, John; Curtis, Helen J; Fisher, Louis; Nab, Linda; Schultze, Anna; Mahalingasivam, Viyaasan; Parker, Edward PK; Hulme, William J; +23 more... Bacon, Sebastian CJ; DeVito, Nicholas J; Bates, Christopher; Evans, David; Inglesby, Peter; Drysdale, Henry; Davy, Simon; Cockburn, Jonathan; Morton, Caroline E; Hickman, George; Ward, Tom; Smith, Rebecca M; Parry, John; Hester, Frank; Harper, Sam; Mehrkar, Amir; Eggo, Rosalind M; Walker, Alex J; Evans, Stephen JW; Douglas, Ian J; MacKenna, Brian; Goldacre, Ben; Tomlinson, Laurie A; (2022) Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform. BMJ (Clinical research ed.), 379. e071932-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj-2022-071932

Österdahl, Marc F; Sinnott, Sarah-Jo; Douglas, Ian; Clegg, Andrew; Tomlinson, Laurie; Wong, Angel; (2022) Frailty and rate of fractures in patients initiating antihypertensive medications: a cohort study in primary care. Drugs and Therapy Perspectives, 38 (1). pp. 41-50. ISSN 1172-0360 DOI: https://doi.org/10.1007/s40267-021-00891-6

Bhaskaran, Krishnan; Bacon, Sebastian; Evans, Stephen Jw; Bates, Chris J; Rentsch, Christopher T; MacKenna, Brian; Tomlinson, Laurie; Walker, Alex J; Schultze, Anna; Morton, Caroline E; +17 more... Grint, Daniel; Mehrkar, Amir; Eggo, Rosalind M; Inglesby, Peter; Douglas, Ian J; McDonald, Helen I; Cockburn, Jonathan; Williamson, Elizabeth J; Evans, David; Curtis, Helen J; Hulme, William J; Parry, John; Hester, Frank; Harper, Sam; Spiegelhalter, David; Smeeth, Liam; Goldacre, Ben; (2021) Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. The Lancet regional health. Europe, 6. 100109-. ISSN 2666-7762 DOI: https://doi.org/10.1016/j.lanepe.2021.100109

Bidulka, Patrick; O'Neill, Stephen; Basu, Anirban; Wilkinson, Samantha; Silverwood, Richard J; Charlton, Paul; Briggs, Andrew; Adler, Amanda I; Khunti, Kamlesh; Tomlinson, Laurie A; +3 more... Smeeth, Liam; Douglas, Ian J; Grieve, Richard; (2021) Protocol for an observational cohort study investigating personalised medicine for intensification of treatment in people with type 2 diabetes mellitus: the PERMIT study. BMJ Open, 11 (9). e046912-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2020-046912

Brown, Jeremy P; Tazare, John R; Williamson, Elizabeth; Mansfield, Kathryn E; Evans, Stephen J; Tomlinson, Laurie A; Bhaskaran, Krishnan; Smeeth, Liam; Wing, Kevin; Douglas, Ian J; (2021) Proton pump inhibitors and risk of all-cause and cause-specific mortality: A cohort study. British journal of clinical pharmacology, 87 (8). pp. 3150-3161. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.14728

Curtis, Helen J; Inglesby, Peter; Morton, Caroline E; MacKenna, Brian; Green, Amelia; Hulme, William; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; +36 more... Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Rowan, Anna; Fisher, Louis; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative); (The OpenSAFELY Collaborative); (2021) Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients’ primary care records in situ using OpenSAFELY. Br J Gen Pract, 72 (714). e51-e62. ISSN 0960-1643 DOI: https://doi.org/10.3399/BJGP.2021.0376

Curtis, Helen J; MacKenna, Brian; Croker, Richard; Inglesby, Peter; Walker, Alex J; Morley, Jessica; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; +26 more... Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben; (The OpenSAFELY Collaborative); The OpenSAFELY Collaborative; (2021) OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19. The British journal of general practice : the journal of the Royal College of General Practitioners, 72 (714). e63-e74. ISSN 0960-1643 DOI: https://doi.org/10.3399/BJGP.2021.0380

Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; +25 more... MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A; (2021) Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England. BMJ: British Medical Journal, 372. n628-. ISSN 1759-2151 DOI: https://doi.org/10.1136/bmj.n628

Grint, Daniel J; Wing, Kevin; Houlihan, Catherine; Gibbs, Hamish P; Evans, Stephen JW; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Walker, Alex J; +27 more... Hickman, George; Nightingale, Emily; Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel YS; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Smeeth, Liam; Goldacre, Ben; Eggo, Rosalind M; (2021) Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England. Clinical infectious diseases, 75 (1). e1120-e1127. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciab754

Grint, Daniel J; Wing, Kevin; Williamson, Elizabeth; McDonald, Helen I; Bhaskaran, Krishnan; Evans, David; Evans, Stephen Jw; Walker, Alex J; Hickman, George; Nightingale, Emily; +26 more... Schultze, Anna; Rentsch, Christopher T; Bates, Chris; Cockburn, Jonathan; Curtis, Helen J; Morton, Caroline E; Bacon, Sebastian; Davy, Simon; Wong, Angel Ys; Mehrkar, Amir; Tomlinson, Laurie; Douglas, Ian J; Mathur, Rohini; Blomquist, Paula; MacKenna, Brian; Ingelsby, Peter; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; DeVito, Nicholas J; Hulme, Will; Tazare, John; Goldacre, Ben; Smeeth, Liam; Eggo, Rosalind M; (2021) Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February. Eurosurveillance, 26 (11). pp. 10-15. ISSN 1025-7917 DOI: https://doi.org/10.2807/1560-7917.ES.2021.26.11.2100256

Iwagami, Masao; Qizilbash, Nawab; Gregson, John; Douglas, Ian; Johnson, Michelle; Pearce, Neil; Evans, Stephen; Pocock, Stuart; (2021) Blood cholesterol and risk of dementia in more than 1·8 million people over two decades: a retrospective cohort study. The Lancet Healthy Longevity, 2 (8). e498-e506. ISSN 2666-7568 DOI: https://doi.org/10.1016/S2666-7568(21)00150-1

Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; +27 more... Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben; (2021) Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. Lancet (London, England), 397 (10286). pp. 1711-1724. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(21)00634-6

OpenSAFELY Collaborative; Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline; Bacon, Seb; Hickman, George; Inglesby, Peter; +22 more... Bates, Chris; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wong, Angel Yun; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian; Smeeth, Liam; Goldacre, Ben; The OpenSAFELY Collaborative; (2021) OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic. Open heart, 8 (2). e001784-e001784. ISSN 2053-3624 DOI: https://doi.org/10.1136/openhrt-2021-001784

OpenSAFELY Collaborative; Wong, Angel YS; Tomlinson, Laurie A; Brown, Jeremy P; Elson, William; Walker, Alex J; Schultze, Anna; Morton, Caroline E; Evans, David; Inglesby, Peter; +21 more... MacKenna, Brian; Bhaskaran, Krishnan; Rentsch, Christopher T; Powell, Emma; Williamson, Elizabeth; Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Cockburn, Jonathan; McDonald, Helen I; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Douglas, Ian J; OpenSAFELY Collaborative; (2021) Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study. Journal of hematology & oncology, 14 (1). 172-. ISSN 1756-8722 DOI: https://doi.org/10.1186/s13045-021-01185-0

Powell, Emma Maud; Douglas, Ian J; Gungabissoon, Usha; Smeeth, Liam; Wing, Kevin; (2021) Real-world effects of medications for stroke prevention in atrial fibrillation: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. BMJ open, 11 (4). e042947-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2020-042947

Prats-Uribe, Albert; Kolovos, Spyros; Berencsi, Klara; Carr, Andrew; Judge, Andrew; Silman, Alan; Arden, Nigel; Petersen, Irene; Douglas, Ian J; Wilkinson, J Mark; +8 more... Murray, David; Valderas, Jose M; Beard, David J; Lamb, Sarah E; Ali, M Sanni; Pinedo-Villanueva, Rafael; Strauss, Victoria Y; Prieto-Alhambra, Daniel; (2021) Unicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting. Health technology assessment (Winchester, England), 25 (66). pp. 1-126. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25660

Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; +13 more... Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen JW; Atkins, David; Justice, Amy C; Freiberg, Matthew S; (2021) Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study. BMJ, 372. n311-. DOI: https://doi.org/10.1136/bmj.n311

Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; +23 more... Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; (2021) Hydroxychloroquine treatment does not reduce COVID-19 mortality; underdosing to the wrong patients? - Authors' reply. The Lancet Rheumatology, 3 (3). e172-e173. ISSN 2665-9913 DOI: https://doi.org/10.1016/S2665-9913(21)00030-8

Schultze, Anna; Douglas, Ian; (2021) COVID-19 and inhaled corticosteroids-another piece in an expanding puzzle. LANCET RESPIRATORY MEDICINE, 9 (7). pp. 674-675. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(21)00076-X

Tazare, John; Walker, Alex J; Tomlinson, Laurie; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; +30 more... Wong, Angel YS; Schultze, Anna; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; Davy, Simon; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Warren-Gash, Charlotte; Bhate, Ketaki; Nitsch, Dorothea; Powell, Emma; Mulick, Amy; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; (2021) Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform. MedRxiv. DOI: https://doi.org/10.1101/2021.01.22.21250304

Walker, Alex J; MacKenna, Brian; Inglesby, Peter; Tomlinson, Laurie; Rentsch, Christopher T; Curtis, Helen J; Morton, Caroline E; Morley, Jessica; Mehrkar, Amir; Bacon, Seb; +31 more... Hickman, George; Bates, Chris; Croker, Richard; Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Williamson, Elizabeth J; Hulme, William J; McDonald, Helen I; Mathur, Rohini; Eggo, Rosalind M; Wing, Kevin; Wong, Angel Ys; Forbes, Harriet; Tazare, John; Parry, John; Hester, Frank; Harper, Sam; O'Hanlon, Shaun; Eavis, Alex; Jarvis, Richard; Avramov, Dima; Griffiths, Paul; Fowles, Aaron; Parkes, Nasreen; Douglas, Ian J; Evans, Stephen Jw; (The OpenSAFELY Collaborative); (2021) Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY. British Journal of General Practice, 71 (712). e806-e814. ISSN 0960-1643 DOI: https://doi.org/10.3399/BJGP.2021.0301

Walker, Alex J; Tazare, John; Hickman, George; Rentsch, Christopher T; Williamson, Elizabeth J; Bhaskaran, Krishnan; Evans, David; Wing, Kevin; Mathur, Rohini; Wong, Angel YS; +24 more... Schultze, Anna; Bacon, Sebastian CJ; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Nightingale, Emily; McDonald, Helen I; Mehrkar, Amir; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Hulme, William J; Forbes, Harriet; Minassian, Caroline; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Eggo, Rosalind M; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie; Goldacre, Ben; (2021) Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic. medRxiv preprint. DOI: https://doi.org/10.1101/2021.02.17.21251812

Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; +8 more... Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen I; (2021) UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. BMC public health, 21 (1). 484-. ISSN 1471-2458 DOI: https://doi.org/10.1186/s12889-021-10427-2

Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; +26 more... Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, Will; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah; (2021) OpenSAFELY: Risks of COVID-19 hospital admission and death for people with learning disabilities - a cohort study. medRxiv preprint. DOI: https://doi.org/10.1101/2021.03.08.21253112

Williamson, Elizabeth J; McDonald, Helen I; Bhaskaran, Krishnan; Walker, Alex J; Bacon, Sebastian; Davy, Simon; Schultze, Anna; Tomlinson, Laurie; Bates, Chris; Ramsay, Mary; +26 more... Curtis, Helen J; Forbes, Harriet; Wing, Kevin; Minassian, Caroline; Tazare, John; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Eggo, Rosalind M; Hulme, William; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; Kuper, Hannah; (2021) Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform. BMJ (Clinical research ed.), 374. n1592-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.n1592

Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; McDonald, Helen I; Walker, Alex J; Tomlinson, Laurie; Wing, Kevin; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; +34 more... Forbes, Harriet; Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, Dave; Inglesby, Peter; MacKenna, Brian; Davies, Nicholas G; DeVito, Nicholas J; Drysdale, Henry; Cockburn, Jonathan; Hulme, Will; Morley, Jess; Douglas, Ian; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Grieve, Richard; Harrison, David A; Steyerberg, Ewout W; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; (2021) Predicting COVID-19 related death using the OpenSAFELY platform. medRxiv preprint. DOI: https://doi.org/10.1101/2021.02.25.21252433

Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian; (2021) Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results. Health technology assessment (Winchester, England), 25 (51). pp. 1-70. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25510

Wong, Angel Ys; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; +23 more... Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Eggo, Rosalind M; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen Jw; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative; (2021) Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19: an OpenSAFELY cohort analysis based on two cohorts. Annals of the rheumatic diseases, 80 (7). pp. 943-951. ISSN 0003-4967 DOI: https://doi.org/10.1136/annrheumdis-2020-219517

Bidulka, Patrick; Iwagami, Masao; Mansfield, Kathryn E; Kalogirou, Fotini; Wong, Angel YS; Douglas, Ian J; Smeeth, Liam; Summers, Charlotte; Tomlinson, Laurie A; (2020) Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study. Wellcome Open Research, 5. 77-. DOI: https://doi.org/10.12688/wellcomeopenres.15873.1

Boddington, Nicola L; Charlett, Andre; Elgohari, Suzanne; Walker, Jemma L; Mcdonald, Helen; Byers, Chloe; Coughlan, Laura; Garcia Vilaplana, Tatiana; Whillock, Rosie; Sinnathamby, Mary; +22 more... Panagiotopoulos, Nikolaos; Letley, Louise; MacDonald, Pauline; Vivancos, Roberto; Edeghere, Obaghe; Shingleton, Joseph; Bennett, Emma; Grint, Daniel J; Strongman, Helen; Mansfield, Kathryn E; Rentsch, Christopher; Minassian, Caroline; Douglas, Ian J; Mathur, Rohini; Peppa, Maria; Cottrell, Simon; McMenamin, Jim; Zambon, Maria; Ramsay, Mary; Dabrera, Gavin; Saliba, Vanessa; Lopez Bernal, Jamie; (2020) COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis. medRxiv preprint. DOI: https://doi.org/10.1101/2020.05.18.20086157 Item availability may be restricted.

Curtis, Helen J; MacKenna, Brian; Walker, Alex J; Croker, Richard; Mehrkar, Amir; Morton, Caroline E; Bacon, Seb; Hickman, George; Inglesby, Peter; Bates, Chris; +24 more... Evans, David; Ward, Tom; Cockburn, Jonathan; Davy, Simon; Bhaskaran, Krishnan; Schultze, Anna; Rentsch, Christopher T; Williamson, Elizabeth; Hulme, William; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Drysdale, Henry; Eggo, Rosalind M; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Douglas, Ian J; Smeeth, Liam; Goldacre, Ben; (2020) OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England. MedRxiv. DOI: https://doi.org/10.1101/2020.12.03.20243535

Dedman, Daniel; Cabecinha, Melissa; Williams, Rachael; Evans, Stephen JW; Bhaskaran, Krishnan; Douglas, Ian J; (2020) Approaches for combining primary care electronic health record data from multiple sources: a systematic review of observational studies. BMJ OPEN, 10 (10). e037405-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2020-037405

Forbes, Harriet; Douglas, Ian; Finn, Adam; Breuer, Judith; Bhaskaran, Krishnan; Smeeth, Liam; Packer, Simon; Langan, Sinéad M; Mansfield, Kathryn E; Marlow, Robin; +2 more... Whitaker, Heather; Warren-Gash, Charlotte; (2020) Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data. BMJ-BRITISH MEDICAL JOURNAL, 368. l6987-. ISSN 1756-1833 DOI: https://doi.org/10.1136/bmj.l6987

Forbes, Harriet; Morton, Caroline E; Bacon, Seb; McDonald, Helen I; Minassian, Caroline; Brown, Jeremy P; Rentsch, Christopher T; Mathur, Rohini; Schultze, Anna; DeVito, Nicholas J; +25 more... MacKenna, Brian; Hulme, William J; Croker, Richard; Walker, Alex J; Williamson, Elizabeth J; Bates, Chris; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Drysdale, Henry; Wong, Angel YS; Cockburn, Jonathan; McManus, Robert; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Smeeth, Liam; Evans, Stephen JW; Bhaskaran, Krishnan; Eggo, Rosalind M; Goldacre, Ben; Tomlinson, Laurie A; (2020) Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England. medRxiv preprint. DOI: https://doi.org/10.1101/2020.11.01.20222315

Mathur, Rohini; Farmer, Ruth E; Eastwood, Sophie V; Chaturvedi, Nish; Douglas, Ian; Smeeth, Liam; (2020) Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study. PLoS medicine, 17 (5). e1003106-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1003106

Mathur, Rohini; Rentsch, Christopher T; Morton, Caroline E; Hulme, William J; Schultze, Anna; MacKenna, Brian; Eggo, Rosalind M; Bhaskaran, Krishnan; Wong, Angel YS; Williamson, Elizabeth J; +28 more... Forbes, Harriet; Wing, Kevin; McDonald, Helen I; Bates, Chris; Bacon, Seb; Walker, Alex J; Evans, David; Inglesby, Peter; Mehrkar, Amir; Curtis, Helen J; DeVito, Nicholas J; Croker, Richard; Drysdale, Henry; Cockburn, Jonathan; Parry, John; Hester, Frank; Harper, Sam; Douglas, Ian J; Tomlinson, Laurie; Evans, Stephen JW; Grieve, Richard; Harrison, David; Rowan, Kathy; Khunti, Kamlesh; Chaturvedi, Nishi; Smeeth, Liam; Goldacre, Ben; OpenSAFELY Collaborative; (2020) Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform. MedRxiv, 397 (10286). pp. 1711-1724. DOI: https://doi.org/10.1016/S0140-6736(21)00634-6

Rentsch, Christopher T; Beckman, Joshua A; Tomlinson, Laurie; Gellad, Walid F; Alcorn, Charles; Kidwai-Khan, Farah; Skanderson, Melissa; Brittain, Evan; King, Joseph T; Ho, Yuk-Lam; +13 more... Eden, Svetlana; Kundu, Suman; Lann, Michael F; Greevy, Robert A; Ho, P Michael; Heidenreich, Paul A; Jacobson, Daniel A; Douglas, Ian J; Tate, Janet P; Evans, Stephen Jw; Atkins, David; Justice, Amy C; Freiberg, Matthew S; (2020) Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States. medRxiv. DOI: https://doi.org/10.1101/2020.12.09.20246579

Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; Hulme, William J; Croker, Richard; Walker, Alex J; +23 more... Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; (2020) Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform. The Lancet Rheumatology, 3 (1). e19-e27. ISSN 2665-9913 DOI: https://doi.org/10.1016/S2665-9913(20)30378-7

Rentsch, Christopher T; DeVito, Nicholas J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Schultze, Anna; J Hulme, William; Croker, Richard; Walker, Alex J; +23 more... Williamson, Elizabeth J; Bates, Chris; Bacon, Seb; Mehrkar, Amir; Curtis, Helen J; Evans, David; Wing, Kevin; Inglesby, Peter; Mathur, Rohini; Drysdale, Henry; Wong, Angel YS; McDonald, Helen I; Cockburn, Jonathan; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Smeeth, Liam; Douglas, Ian J; Dixon, William G; Evans, Stephen JW; Tomlinson, Laurie; Goldacre, Ben; (2020) Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study. lancet rheumatology, 3 (1). E19-E27. DOI: https://doi.org/10.1101/2020.09.04.20187781

Requena, Gema; Douglas, Ian J; Huerta, Consuelo; de Abajo, Francisco; (2020) Impact of pre-exposure time bias in self-controlled case series when the event conditions the exposure: Hip/femur fracture and use of benzodiazepines as a case study. Pharmacoepidemiology and Drug Safety, 29 (4). pp. 388-395. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4959

Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; +22 more... Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; (2020) Inhaled corticosteroid use and risk COVID-19 related death among 966,461 patients with COPD or asthma: an OpenSAFELY analysis. medRxiv preprint. DOI: https://doi.org/10.1101/2020.06.19.20135491

Schultze, Anna; Walker, Alex J; MacKenna, Brian; Morton, Caroline E; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; Croker, Richard; +23 more... Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Wong, Angel YS; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Quint, Jennifer; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; OpenSAFELY Collaborative; OpenSAFELY Collaborative; (2020) Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform. LANCET RESPIRATORY MEDICINE, 8 (11). pp. 1106-1120. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(20)30415-X

Sinnott, Sarah-Jo; Douglas, Ian J; Smeeth, Liam; Williamson, Elizabeth; Tomlinson, Laurie A; (2020) First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care. BMJ-BRITISH MEDICAL JOURNAL, 371. m4080-. ISSN 1756-1833 DOI: https://doi.org/10.1136/bmj.m4080

Tazare, John; Smeeth, Liam; Evans, Stephen JW; Williamson, Elizabeth; Douglas, Ian J; (2020) Implementing high-dimensional propensity score principles to improve confounder adjustment in UK electronic health records. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 29 (11). pp. 1373-1381. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.5121

Tazare, John; Wyss, Richard; Franklin, Jessica M; Smeeth, Liam; Evans, Stephen JW; Wang, Shirley V; Schneeweiss, Sebastian; Douglas, Ian J; Williamson, Elizabeth; Gagne, Joshua J; (2020) Transparency of high-dimensional propensity score analyses: Guidance for diagnostics and reporting. In: CPE All Access 2020. DOI: https://doi.org/10.1002/pds.5412

Walker, Jemma L; Grint, Daniel J; Strongman, Helen; Eggo, Rosalind M; Peppa, Maria; Minassian, Caroline; Mansfield, Kathryn E; Rentsch, Christopher T; Douglas, Ian J; Mathur, Rohini; +8 more... Wong, Angel YS; Quint, Jennifer K; Andrews, Nick; Bernal, Jamie Lopez; Scott, J Anthony; Ramsay, Mary; Smeeth, Liam; McDonald, Helen; (2020) UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records. MedRxiv. DOI: https://doi.org/10.1101/2020.08.24.20179192

Wilkinson, Samantha; Williamson, Elizabeth; Pokrajac, Ana; Fogarty, Damian; Stirnadel-Farrant, Heide; Smeeth, Liam; Douglas, Ian J; Tomlinson, Laurie A; (2020) Comparative effects of sulphonylureas, dipeptidyl peptidase-4 inhibitors and sodium-glucose co-transporter-2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care. Diabetes, obesity & metabolism, 22 (5). pp. 847-856. ISSN 1462-8902 DOI: https://doi.org/10.1111/dom.13970

Williamson, Elizabeth J; Tazare, John; Bhaskaran, Krishnan; Walker, Alex J; McDonald, Helen I; Tomlinson, Laurie A; Bacon, Sebastian; Bates, Chris; Curtis, Helen J; Forbes, Harriet; +32 more... Minassian, Caroline; Morton, Caroline E; Nightingale, Emily; Mehrkar, Amir; Evans, Dave; Nicholson, Brian D; Leon, David; Inglesby, Peter; MacKenna, Brian; Cockburn, Jonathan; Davies, Nicholas G; Hulme, Will J; Morley, Jessica; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Grieve, Richard; Harrison, David; Steyerberg, Ewout; Eggo, Rosalind M; Diaz-Ordaz, Karla; Keogh, Ruth; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; (2020) Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform. Wellcome Open Research, 5. p. 243. DOI: https://doi.org/10.12688/wellcomeopenres.16353.1

Williamson, Elizabeth J; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; +20 more... Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel YS; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Rafael; Evans, Stephen JW; Smeeth, Liam; Goldacre, Ben; (2020) Factors associated with COVID-19-related death using OpenSAFELY. Nature, 584 (7821). pp. 430-436. ISSN 0028-0836 DOI: https://doi.org/10.1038/s41586-020-2521-4

Williamson, Elizabeth; Walker, Alex J; Bhaskaran, Krishnan; Bacon, Seb; Bates, Chris; Morton, Caroline E; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; +20 more... Cockburn, Jonathan; McDonald, Helen I; MacKenna, Brian; Tomlinson, Laurie; Douglas, Ian J; Rentsch, Christopher T; Mathur, Rohini; Wong, Angel; Grieve, Richard; Harrison, David; Forbes, Harriet; Schultze, Anna; Croker, Richard; Parry, John; Hester, Frank; Harper, Sam; Perera, Raf; Evans, Stephen; Smeeth, Liam; Goldacre, Ben; (2020) OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients. MedRxiv. DOI: https://doi.org/10.1101/2020.05.06.20092999 Item availability may be restricted.

Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian; (2020) Real world effects of COPD medications: a cohort study with validation against results from randomised controlled trials. The European respiratory journal, 57 (3). p. 2001586. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01586-2020

Wong, Angel YS; MacKenna, Brian; Morton, Caroline E; Schultze, Anna; Walker, Alex J; Bhaskaran, Krishnan; Brown, Jeremy P; Rentsch, Christopher T; Williamson, Elizabeth; Drysdale, Henry; +21 more... Croker, Richard; Bacon, Seb; Hulme, William; Bates, Chris; Curtis, Helen J; Mehrkar, Amir; Evans, David; Inglesby, Peter; Cockburn, Jonathan; McDonald, Helen I; Tomlinson, Laurie; Mathur, Rohini; Wing, Kevin; Forbes, Harriet; Parry, John; Hester, Frank; Harper, Sam; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; Goldacre, Ben; (2020) OpenSAFELY: Do adults prescribed non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19? medRxiv preprint. 2020.08.12.20171405-. DOI: https://doi.org/10.1101/2020.08.12.20171405 Item availability may be restricted.

Bloom, Chloe I; Douglas, Ian; Olney, Jack; D'Ancona, Grainne; Smeeth, Liam; Quint, Jennifer K; (2019) Cost saving of switching to equivalent inhalers and its effect on health outcomes. THORAX, 74 (11). pp. 1078-1086. ISSN 0040-6376 DOI: https://doi.org/10.1136/thoraxjnl-2018-212957

Brown, Jeremy Philip; Wing, Kevin; Evans, Stephen J; Bhaskaran, Krishnan; Smeeth, Liam; Douglas, Ian J; (2019) Use of real-world evidence in postmarketing medicines regulation in the European Union: a systematic assessment of European Medicines Agency referrals 2013-2017. BMJ open, 9 (10). e028133-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2018-028133

Gregson, J; Qizilbash, N; Iwagami, M; Douglas, I; Johnson, M; Pearce, N; Pocock, S; (2019) Blood pressure and risk of dementia and its subtypes: a historical cohort study with long-term follow-up in 2.6 million people. European journal of neurology, 26 (12). pp. 1479-1486. ISSN 1351-5101 DOI: https://doi.org/10.1111/ene.14030

Lau, Wallis CY; Douglas, Ian J; Wong, Ian CK; Smeeth, Liam; Lip, Gregory YH; Leung, Wai K; Siu, Chung-Wah; Cheung, Bernard MY; Mok, Michael TC; Chan, Esther W; (2019) Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study. Heart Rhythm, 17 (1). pp. 33-40. ISSN 1547-5271 DOI: https://doi.org/10.1016/j.hrthm.2019.07.034

Nissen, FW; (2019) Asthma in electronic health records: validity and phenotyping. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04653375

Nissen, Francis; Douglas, Ian J; Müllerová, Hana; Pearce, Neil; Bloom, Chloe I; Smeeth, Liam; Quint, Jennifer K; (2019) Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink). Journal of asthma and allergy, 12. pp. 7-19. ISSN 1178-6965 DOI: https://doi.org/10.2147/JAA.S182013

Nissen, Francis; Quint, Jennifer K; Morales, Daniel R; Douglas, Ian J; (2019) How to validate a diagnosis recorded in electronic health records. European Respiratory Journal, 15 (1). pp. 64-68. ISSN 0903-1936 DOI: https://doi.org/10.1183/20734735.0344-2018

Root, Adrian; Brown, Jeremy P; Forbes, Harriet J; Bhaskaran, Krishnan; Hayes, Joseph; Smeeth, Liam; Douglas, Ian J; (2019) Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression. JAMA Pediatrics, 173 (11). pp. 1068-1075. ISSN 2168-6203 DOI: https://doi.org/10.1001/jamapediatrics.2019.3194

Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Perel, Pablo; Nitsch, Dorothea; Tomlinson, Laurie A; Douglas, Ian J; (2019) The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data. Pharmacoepidemiology and drug safety, 28 (9). pp. 1267-1277. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4808

Bhaskaran, Krishnan; Dos-Santos-Silva, Isabel; Leon, David A; Douglas, Ian J; Smeeth, Liam; (2018) Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK. The lancet. Diabetes & endocrinology, 6 (12). pp. 944-953. ISSN 2213-8587 DOI: https://doi.org/10.1016/S2213-8587(18)30288-2

Crellin, Elizabeth; Mansfield, Kathryn E; Leyrat, Clémence; Nitsch, Dorothea; Douglas, Ian J; Root, Adrian; Williamson, Elizabeth; Smeeth, Liam; Tomlinson, Laurie A; (2018) Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study. BMJ (Clinical research ed), 360. k341-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.k341

Iwagami, Masao; Tomlinson, Laurie A; Mansfield, Kathryn E; Douglas, Ian J; Smeeth, Liam; Nitsch, Dorothea; (2018) Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study. British journal of clinical pharmacology, 84 (9). pp. 2142-2151. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.13660

Koppe, Uwe; Nitsch, Dorothea; Mansfield, Kathryn E; Mathur, Rohini; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam; Douglas, Ian J; (2018) Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink. BMJ open, 8 (5). e020371-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-020371

Mansfield, Kathryn E; Douglas, Ian J; Nitsch, Dorothea; Thomas, Sara L; Smeeth, Liam; Tomlinson, Laurie A; (2018) Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis. Clinical epidemiology, 10. pp. 187-202. ISSN 1179-1349 DOI: https://doi.org/10.2147/CLEP.S146757

Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K; (2018) Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care. The British journal of general practice, 68 (676). e775-e782. ISSN 0960-1643 DOI: https://doi.org/10.3399/bjgp18X699389

Rothnie, Kieran J; Connell, Olivia; Müllerová, Hana; Smeeth, Liam; Pearce, Neil; Douglas, Ian; Quint, Jennifer K; (2018) Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society, 15 (8). pp. 935-946. ISSN 2329-6933 DOI: https://doi.org/10.1513/AnnalsATS.201710-815OC

Wilkinson, Samantha V; Tomlinson, Laurie A; Iwagami, Masao; Stirnadel-Farrant, Heide A; Smeeth, Liam; Douglas, Ian; (2018) A systematic review comparing the evidence for kidney function outcomes between oral antidiabetic drugs for type 2 diabetes. Wellcome open research, 3. 74-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14660.1

Wilkinson, Samantha; Douglas, Ian J; Williamson, Elizabeth; Stirnadel-Farrant, Heide A; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie A; (2018) Factors associated with choice of intensification treatment for type 2 diabetes after metformin monotherapy: a cohort study in UK primary care. CLINICAL EPIDEMIOLOGY, 10. pp. 1639-1648. ISSN 1179-1349 DOI: https://doi.org/10.2147/CLEP.S176142

Wilkinson, Samantha; Douglas, Ian; Stirnadel-Farrant, Heide; Fogarty, Damian; Pokrajac, Ana; Smeeth, Liam; Tomlinson, Laurie; (2018) Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017. BMJ open, 8 (7). e022768-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2018-022768

Wing, Kevin; Williamson, Elizabeth; Carpenter, James R; Wise, Lesley; Schneeweiss, Sebastian; Smeeth, Liam; Quint, Jennifer K; Douglas, Ian; (2018) Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results. BMJ open, 8 (3). e019475-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-019475

Zhou, Xiaofeng; Douglas, Ian J; Shen, Rongjun; Bate, Andrew; (2018) Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database. Drug Saf, 41 (5). pp. 523-536. ISSN 1179-1942 DOI: https://doi.org/10.1007/s40264-017-0626-y

Bloom, Chloe I; Nissen, Francis; Douglas, Ian J; Smeeth, Liam; Cullinan, Paul; Quint, Jennifer K; (2017) Exacerbation risk and characterisation of the UK's asthma population from infants to old age. Thorax, 73 (4). pp. 313-320. ISSN 0040-6376 DOI: https://doi.org/10.1136/thoraxjnl-2017-210650

Ghebremichael-Weldeselassie, Yonas; Whitaker, Heather J; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy; (2017) Self-controlled case series with multiple event types. Computational statistics & data analysis, 113. pp. 64-72. ISSN 0167-9473 DOI: https://doi.org/10.1016/j.csda.2016.10.010 Full text not available from this repository.

Leyrat, C; Seaman, SR; White, IR; Douglas, I; Smeeth, L; Kim, J; Resche-Rigon, M; Carpenter, JR; Williamson, EJ; (2017) Propensity score analysis with partially observed covariates: How should multiple imputation be used? Statistical methods in medical research. p. 962280217713032. ISSN 0962-2802 DOI: https://doi.org/10.1177/0962280217713032

Mathur, Rohini; Bhaskaran, Krishnan; Edwards, Emma; Lee, Helen; Chaturvedi, Nishi; Smeeth, Liam; Douglas, Ian; (2017) Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014. BMJ open, 7 (2). e014444-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2016-014444

Navaratnam, Vidya; Root, Adrian A; Douglas, Ian; Smeeth, Liam; Hubbard, Richard B; Quint, Jennifer K; (2017) Cardiovascular Outcomes after a Respiratory Tract Infection among Adults with Non-Cystic Fibrosis Bronchiectasis: A General Population-based Study. Annals of the American Thoracic Society, 15 (3). pp. 315-321. ISSN 2329-6933 DOI: https://doi.org/10.1513/AnnalsATS.201706-488OC

Nissen, Francis; Morales, Daniel R; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; Quint, Jennifer K; (2017) Validation of asthma recording in the Clinical Practice Research Datalink (CPRD). BMJ open, 7 (8). e017474-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-017474

Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; (2017) Validation of asthma recording in electronic health records: a systematic review. Clinical epidemiology, 9. pp. 643-656. ISSN 1179-1349 DOI: https://doi.org/10.2147/CLEP.S143718

Nissen, Francis; Quint, Jennifer K; Wilkinson, Samantha; Mullerova, Hana; Smeeth, Liam; Douglas, Ian J; (2017) Validation of asthma recording in electronic health records: protocol for a systematic review. BMJ open, 7 (5). e014694-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2016-014694

Root, Adrian; Douglas, Ian; Evans, Stephen; (2017) Re: Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues. Epidemiology (Cambridge, Mass), 29 (1). e8-. ISSN 1044-3983 DOI: https://doi.org/10.1097/EDE.0000000000000760 Full text not available from this repository.

Sinnott, Sarah-Jo; Smeeth, Liam; Williamson, Elizabeth; Douglas, Ian J; (2017) Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015. BMJ (Clinical research ed), 358. j3984-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.j3984

Tomlinson, Laurie A; Fogarty, Damian G; Douglas, Ian; Nitsch, Dorothea; (2017) Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease? Nephrology, dialysis, transplantation, 32 (suppl_). ii40-ii46. ISSN 0931-0509 DOI: https://doi.org/10.1093/ndt/gfw349

Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; +5 more... Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE-ISPOR Special Task Force on Real World Evidence in He; (2017) Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. Pharmacoepidemiology and drug safety, 26 (9). pp. 1018-1032. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.4295

Wang, Shirley V; Schneeweiss, Sebastian; Berger, Marc L; Brown, Jeffrey; de Vries, Frank; Douglas, Ian; Gagne, Joshua J; Gini, Rosa; Klungel, Olaf; Mullins, C Daniel; +5 more... Nguyen, Michael D; Rassen, Jeremy A; Smeeth, Liam; Sturkenboom, Miriam; joint ISPE‐ISPOR Special Task Force on Real World Evidence in He; (2017) Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0. Value in health, 20 (8). pp. 1009-1022. ISSN 1098-3015 DOI: https://doi.org/10.1016/j.jval.2017.08.3018 Full text not available from this repository.

Whitaker, Heather J; Ghebremichael-Weldeselassie, Yonas; Douglas, Ian J; Smeeth, Liam; Farrington, C Paddy; (2017) Investigating the assumptions of the self-controlled case series method. Statistics in medicine, 37 (4). pp. 643-658. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.7536

Wing, Kevin; Bhaskaran, Krishnan; Pealing, Louise; Root, Adrian; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian; (2017) Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study. The Journal of antimicrobial chemotherapy, 72 (9). pp. 2636-2646. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkx183

Yates, Tom A; Tomlinson, Laurie A; Bhaskaran, Krishnan; Langan, Sinead; Thomas, Sara; Smeeth, Liam; Douglas, Ian J; (2017) Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort. PLoS medicine, 14 (11). e1002457-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1002457

Beau-Lejdstrom, Raphaelle; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam; (2016) Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence. BMJ open, 6 (6). e010508-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2015-010508

Chui, Celine SL; Chan, Esther W; Wong, Angel YS; Root, Adrian; Douglas, Ian J; Wong, Ian CK; (2016) Association between oral fluoroquinolones and seizures: A self-controlled case series study. Neurology, 86 (18). pp. 1708-1715. ISSN 0028-3878 DOI: https://doi.org/10.1212/WNL.0000000000002633

Douglas, Ian J; Root, Adrian; Krishnan, Bhaskaran; (2016) Oral Fluoroquinolone Use and Retinal Detachment. JAMA ophthalmology, 134 (12). 1448-. ISSN 2168-6165 DOI: https://doi.org/10.1001/jamaophthalmol.2016.3477

Matthews, Anthony; Langan, Sinéad M; Douglas, Ian J; Smeeth, Liam; Bhaskaran, Krishnan; (2016) Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink. PLoS medicine, 13 (6). e1002037-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1002037

Petersen, Irene; Douglas, Ian; Whitaker, Heather; (2016) Self controlled case series methods: an alternative to standard epidemiological study designs. BMJ (Clinical research ed), 354. i4515-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.i4515

Rawlins, Michael D; Wexler, Nancy S; Wexler, Alice R; Tabrizi, Sarah J; Douglas, Ian; Evans, Stephen JW; Smeeth, Liam; (2016) The Prevalence of Huntington's Disease. Neuroepidemiology, 46 (2). pp. 144-153. ISSN 0251-5350 DOI: https://doi.org/10.1159/000443738

Rañopa, ME; (2016) Methodological issues in electronic healthcare database studies of drug cancer associations: identification of cancer, and drivers of discrepant results. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.02572609

Root, AA; Wong, AY; Ghebremichael-Weldeselassie, Y; Smeeth, L; Bhaskaran, K; Evans, SJ; Brauer, R; Wong, IC; Navaratnam, V; Douglas, I; (2016) Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs. British journal of clinical pharmacology, 82 (2). pp. 512-21. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.12983

Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I; (2016) OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. [Conference or Workshop Item] https://doi.org/10.1097/01.hjh.0000499998.88068.07 Full text not available from this repository.

Sinnott, SJ; Root, A; Mathur, R; Mansfield, K; Tomlinson, L; Douglas, I; (2016) OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS. [Conference or Workshop Item] https://doi.org/10.1097/01.hjh.0000499998.88068.07 Full text not available from this repository.

Sinnott, SJ; Tomlinson, LA; Root, AA; Mathur, R; Mansfield, KE; Smeeth, L; Douglas, IJ; (2016) Comparative effectiveness of fourth-line anti-hypertensive agents in resistant hypertension: A systematic review and meta-analysis. European journal of preventive cardiology. ISSN 2047-4873 DOI: https://doi.org/10.1177/2047487316675194

Wexler, Nancy S; Collett, Laura; Wexler, Alice R; Rawlins, Michael D; Tabrizi, Sarah J; Douglas, Ian; Smeeth, Liam; Evans, Stephen J; (2016) Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review. BMJ open, 6 (2). e009070-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2015-009070

Wing, Kevin; (2016) Improving the measurement and detection of serious adverse drug reactions in databases of stored electronic health records. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.02545199

Wing, Kevin; Bhaskaran, Krishnan; Smeeth, Liam; van Staa, Tjeerd P; Klungel, Olaf H; Reynolds, Robert F; Douglas, Ian; (2016) Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury. BMJ open, 6 (9). e012102-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2016-012102

Wong, Angel YS; Root, Adrian; Douglas, Ian J; Chui, Celine SL; Chan, Esther W; Ghebremichael-Weldeselassie, Yonas; Siu, Chung-Wah; Smeeth, Liam; Wong, Ian CK; (2016) Cardiovascular outcomes associated with use of clarithromycin: population based study. BMJ (Clinical research ed), 352. h6926-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.h6926

de Groot, MC; Candore, G; Uddin, MJ; Souverein, PC; Ali, MS; Belitser, SV; Huerta, C; Groenwold, RH; Alvarez, Y; Slattery, J; +9 more... Korevaar, J; Hoes, AW; Roes, KC; de Boer, A; Douglas, IJ; Schlienger, RG; Reynolds, R; Klungel, OH; Gardarsdottir, H; (2016) Case-only designs for studying the association of antidepressants and hip or femur fracture. Pharmacoepidemiology and drug safety, 25 Sup. pp. 103-113. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3850

Brauer, Ruth; Bhaskaran, Krishnan; Chaturvedi, Nishi; Dexter, David T; Smeeth, Liam; Douglas, Ian; (2015) Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study. PLoS medicine, 12 (7). e1001854-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001854

Brauer, Ruth; Douglas, Ian; Garcia Rodriguez, Luis Alberto; Downey, Gerald; Huerta, Consuelo; de Abajo, Francisco; Bate, Andrew; Feudjo Tepie, Maurille; de Groot, Mark CH; Schlienger, Raymond; +4 more... Reynolds, Robert; Smeeth, Liam; Klungel, Olaf; Ruigómez, Ana; (2015) Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe. Pharmacoepidemiology and drug safety, 25 Sup (S1). pp. 29-38. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3861 Full text not available from this repository.

Brauer, Ruth; Ruigómez, Ana; Downey, Gerry; Bate, Andrew; Garcia Rodriguez, Luis Alberto; Huerta, Consuelo; Gil, Miguel; de Abajo, Francisco; Requena, Gema; Alvarez, Yolanda; +13 more... Slattery, Jim; de Groot, Mark; Souverein, Patrick; Hesse, Ulrik; Rottenkolber, Marietta; Schmiedl, Sven; de Vries, Frank; Tepie, Maurille Feudjo; Schlienger, Raymond; Smeeth, Liam; Douglas, Ian; Reynolds, Robert; Klungel, Olaf; (2015) Prevalence of antibiotic use: a comparison across various European health care data sources. Pharmacoepidemiology and drug safety, 25 Sup (Suppl ). pp. 11-20. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3831

Brauer, Ruth; Ruigómez, Ana; Klungel, Olaf; Reynolds, Robert; Feudjo Tepie, Maurille; Smeeth, Liam; Douglas, Ian; (2015) The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies. Pharmacoepidemiology and drug safety, 25 Sup (Suppl ). pp. 39-46. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3846

Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam; (2015) Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care. PLoS medicine, 12 (12). e1001925-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001925

Douglas, Ian J; Bhaskaran, Krishnan; Batterham, Rachel L; Smeeth, Liam; (2015) The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort. British journal of clinical pharmacology, 79 (6). pp. 1020-1027. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.12578

Hayes, JF; Bhaskaran, K; Batterham, R; Smeeth, L; Douglas, I; (2015) The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom. Int J Obes (Lond), 39 (9). pp. 1359-1364. ISSN 1476-5497 DOI: https://doi.org/10.1038/ijo.2015.86

Minassian, C; Thomas, S; Smeeth, L; Douglas, I; Brauer, R; Langan, S; (2015) Herpes zoster, acute cardiovascular events and the role of zoster vaccination. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/2312518 Full text not available from this repository.

Minassian, Caroline; Thomas, Sara L; Smeeth, Liam; Douglas, Ian; Brauer, Ruth; Langan, Sinéad M; (2015) Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States. PLoS medicine, 12 (12). e1001919-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001919

Qizilbash, Nawab; Gregson, John; Johnson, Michelle E; Pearce, Neil; Douglas, Ian; Wing, Kevin; Evans, Stephen JW; Pocock, Stuart J; (2015) BMI and risk of dementia in two million people over two decades: a retrospective cohort study. The lancet Diabetes & endocrinology, 3 (6). pp. 431-436. ISSN 2213-8587 DOI: https://doi.org/10.1016/S2213-8587(15)00033-9 Full text not available from this repository.

Requena, Gema; Logie, John; Martin, Elisa; Boudiaf, Nada; González González, Rocío; Huerta, Consuelo; Alvarez, Arturo; Webb, David; Bate, Andrew; García Rodríguez, Luis A; +7 more... Reynolds, Robert; Schlienger, Raymond; Gardarsdottir, Helga; de Groot, Mark; Klungel, Olaf H; de Abajo, Fancisco; Douglas, Ian J; (2015) Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines. Pharmacoepidemiology and drug safety, 25 Sup (Suppl ). pp. 79-87. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3822

Thomsen, RW; Christensen, DH; Kahlert, J; Knudsen, ST; Pedersen, L; Norrelund, H; Dekkers, OM; Douglas, I; Marchesini, G; Smeeth, L; +4 more... Moller, N; Beck-Nielsen, H; Jorgensen, JO; Sorensen, HT; (2015) Risk of pancreatic cancer associated with use of incretin-based therapy and other glucose-lowering agents: a nationwide case-control study in Denmark. Diabetologia, 58. S8-S9. ISSN 0012-186X https://researchonline.lshtm.ac.uk/id/eprint/2312529 Full text not available from this repository.

Bhaskaran, Krishnan; Douglas, Ian; Forbes, Harriet; dos-Santos-Silva, Isabel; Leon, David A; Smeeth, Liam; (2014) Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults. Lancet, 384 (9945). pp. 755-765. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(14)60892-8

Brauer, Ruth; Smeeth, Liam; Anaya-Izquierdo, Karim; Timmis, Adam; Denaxas, Spiros C; Farrington, C Paddy; Whitaker, Heather; Hemingway, Harry; Douglas, Ian; (2014) Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study. European heart journal, 36 (16). pp. 984-992. ISSN 0195-668X DOI: https://doi.org/10.1093/eurheartj/ehu263

Goh, Kah L; Bhaskaran, Krishnan; Minassian, Caroline; Evans, Stephen JW; Smeeth, Liam; Douglas, Ian J; (2014) Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink. British journal of clinical pharmacology, 79 (2). pp. 337-350. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.12511

Macedo, Ana Filipa; Douglas, Ian; Smeeth, Liam; Forbes, Harriet; Ebrahim, Shah; (2014) Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink. BMC cardiovascular disorders, 14 (1). 85-. ISSN 1471-2261 DOI: https://doi.org/10.1186/1471-2261-14-85

Man, Kenneth KC; Chan, Esther W; Coghill, David; Douglas, Ian; Ip, Patrick; Leung, Ling-Pong; Tsui, Matthew SH; Wong, Wilfred HS; Wong, Ian CK; (2014) Methylphenidate and the risk of trauma. Pediatrics, 135 (1). pp. 40-48. ISSN 0031-4005 DOI: https://doi.org/10.1542/peds.2014-1738 Full text not available from this repository.

Perel, Pablo; Clayton, Tim; Altman, Doug G; Croft, Peter; Douglas, Ian; Hemingway, Harry; Hingorani, Aroon; Morley, Katherine I; Riley, Richard; Timmis, Adam; +3 more... Van der Windt, Danielle; Roberts, Ian; PROGRESS Partnership; (2014) Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study. PLoS medicine, 11 (6). e1001664-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001664

Rañopa, Michael; Douglas, Ian; van Staa, Tjeerd; Smeeth, Liam; Klungel, Olaf; Reynolds, Robert; Bhaskaran, Krishnan; (2014) The identification of incident cancers in UK primary care databases: a systematic review. Pharmacoepidemiology and drug safety, 24 (1). pp. 11-18. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.3729 Full text not available from this repository.

Bhaskaran, Krishnan; Forbes, Harriet J; Douglas, Ian; Leon, David A; Smeeth, Liam; (2013) Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD). BMJ open, 3 (9). e003389-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2013-003389

Douglas, Ian J; Langham, Julia; Bhaskaran, Krishnan; Brauer, Ruth; Smeeth, Liam; (2013) Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink. BMJ (Clinical research ed), 346 (apr12). f1936-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.f1936

Douglas, Ian; Evans, Stephen; Rawlins, Michael D; Smeeth, Liam; Tabrizi, Sarah J; Wexler, Nancy S; (2013) Juvenile Huntington's disease: a population-based study using the General Practice Research Database. BMJ open, 3 (4). e002085-e002085. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2012-002085

Evans, Stephen JW; Douglas, Ian; Rawlins, Michael D; Wexler, Nancy S; Tabrizi, Sarah J; Smeeth, Liam; (2013) Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records. Journal of neurology, neurosurgery, and psychiatry, 84 (10). pp. 1156-1160. ISSN 0022-3050 DOI: https://doi.org/10.1136/jnnp-2012-304636

Skow, Aine; Douglas, Ian; Smeeth, Liam; (2013) The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database. British journal of clinical pharmacology, 76 (5). pp. 816-822. ISSN 0306-5251 DOI: https://doi.org/10.1111/bcp.12100

Wing, Kevin; Douglas, Ian; Bhaskaran, Krishnan; Klungel, Olaf H; Reynolds, Robert F; Pirmohamed, Munir; Smeeth, Liam; van Staa, Tjeerd P; (2013) Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records. Drug discovery today, 19 (4). pp. 361-366. ISSN 1359-6446 DOI: https://doi.org/10.1016/j.drudis.2013.11.003

Bhaskaran, Krishnan; Douglas, Ian; Evans, Stephen; van Staa, Tjeerd; Smeeth, Liam; (2012) Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database. BMJ (Clinical research ed), 344 (apr24). e2697-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.e2697

Brauer, R; Smeeth, L; Anaya-Izquierdo, K; Farrington, CP; Whitaker, H; Douglas, I; (2012) A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/612561 Full text not available from this repository.

Douglas, Ian J; Evans, Stephen JW; Hingorani, Aroon D; Grosso, Anthony M; Timmis, Adam; Hemingway, Harry; Smeeth, Liam; (2012) Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs. BMJ (Clinical research ed), 345 (jul10). e4388-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.e4388

Beau, R; Douglas, I; Evans, S; Clayton, T; Smeeth, L; (2011) How Long Do Children Stay on Antiepileptic Treatments in the UK? [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/2 Full text not available from this repository.

Beau, R; Douglas, I; Stephen, E; Clayton, T; Smeeth, L; (2011) Comparison of Retention Rates of First Line Antiepileptic Drugs in Children in the UK. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/1 Full text not available from this repository.

Bhaskaran, K; Douglas, I; Evans, S; van Staa, T; Smeeth, L; (2011) The Risk of Cancer Associated with Angiotensin-II Receptor Blockers. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/5 Full text not available from this repository.

Brauer, R; Douglas, I; Smeeth, L; (2011) Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-Registered Users of Antipsychotic Agents. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/6 Full text not available from this repository.

Brauer, Ruth; Douglas, Ian; Smeeth, Liam; (2011) The association between antipsychotic agents and the risk of myocardial infarction: a systematic review. British journal of clinical pharmacology, 72 (6). pp. 871-878. ISSN 0306-5251 DOI: https://doi.org/10.1111/j.1365-2125.2011.04043.x

Douglas, I; Smeeth, L; Hingorani, A; Grosso, A; Evans, S; (2011) A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between Clopidogrel and Cytochrome P450 2C19 Inhibitors. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/7 Full text not available from this repository.

Douglas, Ian; Evans, Stephen; Smeeth, Liam; (2011) Effect of statin treatment on short term mortality after pneumonia episode: cohort study. BMJ, 342 (apr06). d1642-. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.d1642

Douglas, Ian; Smeeth, Liam; Irvine, David; (2011) The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study. British journal of clinical pharmacology, 71 (1). pp. 116-120. ISSN 0306-5251 DOI: https://doi.org/10.1111/j.1365-2125.2010.03797.x Full text not available from this repository.

Farrington, C Paddy; Anaya-Izquierdo, Karim; Whitaker, Heather J; Hocine, Mounia N; Douglas, Ian; Smeeth, Liam; (2011) Self-Controlled Case Series Analysis With Event-Dependent Observation Periods. Journal of the American Statistical Association, 106 (494). pp. 417-426. ISSN 0162-1459 DOI: https://doi.org/10.1198/jasa.2011.ap10108 Full text not available from this repository.

Grosso, Anthony; Douglas, Ian; MacAllister, Raymond; Petersen, Irene; Smeeth, Liam; Hingorani, Aroon D; (2011) Use of the self-controlled case series method in drug safety assessment. Expert opinion on drug safety, 10 (3). pp. 337-340. ISSN 1474-0338 DOI: https://doi.org/10.1517/14740338.2011.562187

Langham, Julia; Douglas, Ian; Brauer, Ruth; Bhaskaran, Krishnan; Smeeth, Liam; (2011) Abstracts of the 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management. Chicago, Illinois, USA. August 14-17, 2011. Pharmacoepidemiology and drug safety, 20 Sup (S1). S1-364. ISSN 1053-8569 DOI: https://doi.org/10.1002/pds.2206 Full text not available from this repository.

McCandless, Lawrence C; Douglas, Ian J; Evans, Stephen J; Smeeth, Liam; (2011) Cutting feedback in Bayesian regression adjustment for the propensity score. The international journal of biostatistics, 6 (2). Article-16. ISSN 2194-573X DOI: https://doi.org/10.2202/1557-4679.1205

Douglas, Ian J; Evans, Stephen J; Pocock, Stuart; Smeeth, Liam; (2009) The risk of fractures associated with thiazolidinediones: a self-controlled case-series study. PLoS medicine, 6 (9). e1000154-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1000154

Grosso, Anthony; Douglas, Ian; Hingorani, Aroon D; MacAllister, Raymond; Hubbard, Richard; Smeeth, Liam; (2009) Inhaled tiotropium bromide and risk of stroke. British journal of clinical pharmacology, 68 (5). pp. 731-736. ISSN 0306-5251 DOI: https://doi.org/10.1111/j.1365-2125.2009.03517.x Full text not available from this repository.

Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam; (2009) Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis. PloS one, 4 (3). e4720-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0004720

Maguire, A; Douglas, I; Blak, BT; (2009) THE APPLICATION OF DISCRETE EVENT SIMULATION TO QUANTITATIVE RISK BENEFIT ANALYSIS. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/4488 Full text not available from this repository.

Smeeth, Liam; Douglas, Ian; Hall, Andrew J; Hubbard, Richard; Evans, Stephen; (2009) Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials. British journal of clinical pharmacology, 67 (1). pp. 99-109. ISSN 0306-5251 DOI: https://doi.org/10.1111/j.1365-2125.2008.03308.x Full text not available from this repository.

Douglas, Ian J; Smeeth, Liam; (2008) Exposure to antipsychotics and risk of stroke: self controlled case series study. BMJ, 337 (aug28). a1227-. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.a1227

Grosso, Anthony; Douglas, Ian; Hingorani, Aroon; MacAllister, Raymond; Smeeth, Liam; (2008) Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions. British journal of clinical pharmacology, 66 (5). pp. 689-694. ISSN 0306-5251 DOI: https://doi.org/10.1111/j.1365-2125.2008.03273.x Full text not available from this repository.

Nitsch, Dorothea; Douglas, Ian; Smeeth, Liam; Fletcher, Astrid; (2008) Age-related macular degeneration and complement activation-related diseases: a population-based case-control study. Ophthalmology, 115 (11). pp. 1904-1910. ISSN 0161-6420 DOI: https://doi.org/10.1016/j.ophtha.2008.06.035 Full text not available from this repository.

Douglas, IJ; Smeeth, L; Evans, SJ; (2007) A propensity score controlled cohort study to investigate the effects of statins. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8492 Full text not available from this repository.

Douglas, Ian J; Cook, Claire; Chakravarthy, Usha; Hubbard, Richard; Fletcher, Astrid E; Smeeth, Liam; (2007) A case-control study of drug risk factors for age-related macular degeneration. Ophthalmology, 114 (6). pp. 1164-1169. ISSN 0161-6420 DOI: https://doi.org/10.1016/j.ophtha.2006.09.018 Full text not available from this repository.

Maguire, A; Douglas, I; Smeeth, L; (2007) Patterns of cholesterol levels in patients treated with lipid lowering drugs in UK primary care. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8494 Full text not available from this repository.

Maguire, A; Douglas, I; Smeeth, L; Thompson, M; (2007) Determinants of cholesterol and triglycerides recording in patients treated with lipid lowering therapy in UK primary care. [Conference or Workshop Item] https://doi.org/10.1002/pds Full text not available from this repository.

Maguire, A; Schwalm, MS; Douglas, I; Smeeth, L; (2007) Classification of hyperlipidemia from automated primary care data in the UK and France. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8491 Full text not available from this repository.

Smeeth, Liam; Douglas, Ian; Hubbard, Richard; (2006) Commentary: we still need observational studies of drugs--they just need to be better. International journal of epidemiology, 35 (5). pp. 1310-1311. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyl134 Full text not available from this repository.