Items where Author or Contributor is "Douglas, I"
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Number of items: 189.
2024
Bidulka, Patrick;
Lugo-Palacios, David G;
Carroll, Orlagh;
O'Neill, Stephen;
Adler, Amanda I;
Basu, Anirban;
Silverwood, Richard J;
Bartlett, Jonathan W;
Nitsch, Dorothea;
Charlton, Paul;
+5 more...
Briggs, Andrew H;
Smeeth, Liam;
Douglas, Ian J;
Khunti, Kamlesh;
Grieve, Richard;
(2024)
Comparative effectiveness of second line oral antidiabetic treatments among people with type 2 diabetes mellitus: emulation of a target trial using routinely collected health data.
BMJ, 385.
e077097-.
DOI: https://doi.org/10.1136/bmj-2023-077097
Brown, Jeremy P;
Hunnicutt, Jacob N;
Ali, M Sanni;
Bhaskaran, Krishnan;
Cole, Ashley;
Langan, Sinead M;
Nitsch, Dorothea;
Rentsch, Christopher T;
Galwey, Nicholas W;
Wing, Kevin;
+1 more...
Douglas, Ian J;
(2024)
Quantifying possible bias in clinical and epidemiological studies with quantitative bias analysis: common approaches and limitations.
BMJ, 385.
e076365-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj-2023-076365
Coste, Astrid;
Wong, Angel Ys;
Warren-Gash, Charlotte;
Matthewman, Julian;
Bate, Andrew;
Douglas, Ian J;
(2024)
Implementation of a Taxonomy-Based Framework for the Selection of Appropriate Drugs and Outcomes for Real-World Data Signal Detection Studies.
Drug safety, 47 (2).
pp. 183-192.
ISSN 0114-5916
DOI: https://doi.org/10.1007/s40264-023-01382-5
Dedman, Daniel;
Williams, Rachael;
Bhaskaran, Krishnan;
Douglas, Ian J;
(2024)
Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases.
BMJ open, 14 (2).
e070258-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2022-070258
Douglas, Ian J;
Peh, Jerlyn;
Mansfield, Kathryn E;
Trelfa, Anna;
Fowler, Tom;
Boulter, Matthew;
Cleary, Paul;
Smith, Jenifer;
Edmunds, W John;
(2024)
A self-controlled case series study to measure the risk of SARS-CoV-2 infection associated with attendance at sporting and cultural events: the UK Events Research Programme events.
BMC medicine, 22 (1).
100-.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-024-03276-4
Schultze, Anna;
Brown, Jeremy;
Logie, John;
Cunnington, Marianne;
Requena, Gema;
Gillespie, Iain A;
Evans, Stephen JW;
Douglas, Ian;
Galwey, Nicholas;
(2024)
Overcoming Time-Varying Confounding in Self-Controlled Case Series with Active Comparators: Application and Recommendations.
American journal of epidemiology.
kwae216-.
ISSN 0002-9262
DOI: https://doi.org/10.1093/aje/kwae216
(In Press)
Schultze, Anna;
Martin, Ivonne;
Messina, Davide;
Bots, Sophie;
Belitser, Svetlana;
José Carreras-Martínez, Juan;
Correcher-Martinez, Elisa;
Urchueguía-Fornes, Arantxa;
Martín-Pérez, Mar;
García-Poza, Patricia;
+11 more...
Villalobos, Felipe;
Pallejà-Millán, Meritxell;
Alberto Bissacco, Carlo;
Segundo, Elena;
Souverein, Patrick;
Riefolo, Fabio;
Durán, Carlos E;
Gini, Rosa;
Sturkenboom, Miriam;
Klungel, Olaf;
Douglas, Ian;
(2024)
A comparison of four self-controlled study designs in an analysis of COVID-19 vaccines and myocarditis using five European databases.
Vaccine, 42 (12).
pp. 3039-3048.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2024.03.043
2023
Baptiste, PJ;
(2023)
Real-world effectiveness and adverse events caused by ACE inhibitors and ARBs for reduction in cardiovascular events with validation against the ONTARGET trial.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04671559
Brown, JP;
(2023)
Application of methods for handling unmeasured confounding in pharmacoepidemiological studies.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04671281
Brown, Jeremy P;
Wing, Kevin;
Leyrat, Clémence;
Evans, Stephen J;
Mansfield, Kathryn E;
Wong, Angel YS;
Smeeth, Liam;
Galwey, Nicholas W;
Douglas, Ian J;
(2023)
Association Between Fluoroquinolone Use and Hospitalization With Aortic Aneurysm or Aortic Dissection.
JAMA cardiology, 8 (9).
pp. 865-870.
ISSN 2380-6583
DOI: https://doi.org/10.1001/jamacardio.2023.2418
Green, Amelia CA;
Curtis, Helen J;
Higgins, Rose;
Nab, Linda;
Mahalingasivam, Viyaasan;
Smith, Rebecca M;
Mehrkar, Amir;
Inglesby, Peter;
Drysdale, Henry;
DeVito, Nicholas J;
+32 more...
Croker, Richard;
Rentsch, Christopher T;
Bhaskaran, Krishnan;
Tazare, John;
Zheng, Bang;
Andrews, Colm D;
Bacon, Sebastian CJ;
Davy, Simon;
Dillingham, Iain;
Evans, David;
Fisher, Louis;
Hickman, George;
Hopcroft, Lisa EM;
Hulme, William J;
Massey, Jon;
MacDonald, Orla;
Morley, Jessica;
Morton, Caroline E;
Park, Robin Y;
Walker, Alex J;
Ward, Tom;
Wiedemann, Milan;
Bates, Christopher;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Evans, Stephen JW;
Goldacre, Ben;
Tomlinson, Laurie A;
MacKenna, Brian;
(2023)
Trends, variation, and clinical characteristics of recipients of antiviral drugs and neutralising monoclonal antibodies for covid-19 in community settings: retrospective, descriptive cohort study of 23.4 million people in OpenSAFELY.
BMJ Medicine, 2 (1).
e000276-.
ISSN 2754-0413
DOI: https://doi.org/10.1136/bmjmed-2022-000276
Tazare, John;
Gibbons, Daniel C;
Bokern, Marleen;
Williamson, Elizabeth J;
Gillespie, Iain A;
Cunnington, Marianne;
Logie, John;
Douglas, Ian J;
(2023)
Prevalent new user designs: A literature review of current implementation practice.
Pharmacoepidemiology and drug safety, 32 (11).
pp. 1252-1260.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.5656
Zheng, Bang;
Campbell, Jacqueline;
Carr, Edward J;
Tazare, John;
Nab, Linda;
Mahalingasivam, Viyaasan;
Mehrkar, Amir;
Santhakumaran, Shalini;
Steenkamp, Retha;
Loud, Fiona;
+15 more...
Lyon, Susan;
Scanlon, Miranda;
Hulme, William J;
Green, Amelia CA;
Curtis, Helen J;
Fisher, Louis;
Parker, Edward;
Goldacre, Ben;
Douglas, Ian;
Evans, Stephen;
MacKenna, Brian;
Bell, Samira;
Tomlinson, Laurie A;
Nitsch, Dorothea;
OpenSAFELY Collaborative and LH&W NCS (or CONVALESCENCE) Collabo;
(2023)
Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in patients on kidney replacement therapy: observational study using the OpenSAFELY-UKRR and SRR databases.
Clinical kidney journal, 16 (11).
pp. 2048-2058.
ISSN 2048-8505
DOI: https://doi.org/10.1093/ckj/sfad184
Zheng, Bang;
Tazare, John;
Nab, Linda;
Green, Amelia Ca;
Curtis, Helen J;
Mahalingasivam, Viyaasan;
Herrett, Emily L;
Costello, Ruth E;
Eggo, Rosalind M;
Speed, Victoria;
+15 more...
Bacon, Sebastian Cj;
Bates, Christopher;
Parry, John;
Cockburn, Jonathan;
Hester, Frank;
Harper, Sam;
Schaffer, Andrea L;
Hulme, William J;
Mehrkar, Amir;
Evans, Stephen Jw;
MacKenna, Brian;
Goldacre, Ben;
Douglas, Ian J;
Tomlinson, Laurie A;
OpenSAFELY Collaborative;
(2023)
Comparative effectiveness of nirmatrelvir/ritonavir versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised high-risk patients during Omicron waves: observational cohort study using the OpenSAFELY platform.
The Lancet Regional Health - Europe, 34.
100741-.
DOI: https://doi.org/10.1016/j.lanepe.2023.100741
2022
Bhaskaran, Krishnan;
Rentsch, Christopher T;
Hickman, George;
Hulme, William J;
Schultze, Anna;
Curtis, Helen J;
Wing, Kevin;
Warren-Gash, Charlotte;
Tomlinson, Laurie;
Bates, Chris J;
+22 more...
Mathur, Rohini;
MacKenna, Brian;
Mahalingasivam, Viyaasan;
Wong, Angel;
Walker, Alex J;
Morton, Caroline E;
Grint, Daniel;
Mehrkar, Amir;
Eggo, Rosalind M;
Inglesby, Peter;
Douglas, Ian J;
McDonald, Helen I;
Cockburn, Jonathan;
Williamson, Elizabeth J;
Evans, David;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen Jw;
Bacon, Sebastian;
Smeeth, Liam;
Goldacre, Ben;
(2022)
Overall and cause-specific hospitalisation and death after COVID-19 hospitalisation in England: A cohort study using linked primary care, secondary care, and death registration data in the OpenSAFELY platform.
PLoS medicine, 19 (1).
e1003871-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1003871
Bidulka, Patrick;
Mathur, Rohini;
Lugo-Palacios, David G;
O'Neill, Stephen;
Basu, Anirban;
Silverwood, Richard J;
Charlton, Paul;
Briggs, Andrew;
Smeeth, Liam;
Adler, Amanda I;
+3 more...
Douglas, Ian J;
Khunti, Kamlesh;
Grieve, Richard;
(2022)
Ethnic and socioeconomic disparities in initiation of second-line antidiabetic treatment for people with type 2 diabetes in England: A cross-sectional study.
Diabetes, obesity & metabolism, 25 (1).
pp. 282-292.
ISSN 1462-8902
DOI: https://doi.org/10.1111/dom.14874
Bots, Sophie H;
Riera-Arnau, Judit;
Belitser, Svetlana V;
Messina, Davide;
Aragón, Maria;
Alsina, Ema;
Douglas, Ian J;
Durán, Carlos E;
García-Poza, Patricia;
Gini, Rosa;
+14 more...
Herings, Ron MC;
Huerta, Consuelo;
Sisay, Malede Mequanent;
Martín-Pérez, Mar;
Martin, Ivonne;
Overbeek, Jetty A;
Paoletti, Olga;
Pallejà-Millán, Meritxell;
Schultze, Anna;
Souverein, Patrick;
Swart, Karin MA;
Villalobos, Felipe;
Klungel, Olaf H;
Sturkenboom, Miriam CJM;
(2022)
Myocarditis and pericarditis associated with SARS-CoV-2 vaccines: A population-based descriptive cohort and a nested self-controlled risk interval study using electronic health care data from four European countries.
Frontiers in pharmacology, 13.
1038043-.
ISSN 1663-9812
DOI: https://doi.org/10.3389/fphar.2022.1038043
Chui, Celine SL;
Cheung, Ka Shing;
Brown, Jeremy P;
Douglas, Ian J;
Wong, Ian CK;
Chan, Esther W;
Wong, Angel YS;
(2022)
Proton pump inhibitors and myocardial infarction: an application of active comparators in a self-controlled case series.
International journal of epidemiology, 52 (3).
pp. 899-907.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyac196
Coste, Astrid;
Wong, Angel;
Bokern, Marleen;
Bate, Andrew;
Douglas, Ian J;
(2022)
Methods for drug safety signal detection using routinely collected observational electronic health care data: A systematic review.
Pharmacoepidemiology and drug safety, 32 (1).
pp. 28-43.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.5548
Curtis, Helen J;
Inglesby, Peter;
MacKenna, Brian;
Croker, Richard;
Hulme, William J;
Rentsch, Christopher T;
Bhaskaran, Krishnan;
Mathur, Rohini;
Morton, Caroline E;
Bacon, Sebastian Cj;
+27 more...
Smith, Rebecca M;
Evans, David;
Mehrkar, Amir;
Tomlinson, Laurie;
Walker, Alex J;
Bates, Christopher;
Hickman, George;
Ward, Tom;
Morley, Jessica;
Cockburn, Jonathan;
Davy, Simon;
Williamson, Elizabeth J;
Eggo, Rosalind M;
Parry, John;
Hester, Frank;
Harper, Sam;
O'Hanlon, Shaun;
Eavis, Alex;
Jarvis, Richard;
Avramov, Dima;
Griffiths, Paul;
Fowles, Aaron;
Parkes, Nasreen;
Evans, Stephen Jw;
Douglas, Ian J;
Smeeth, Liam;
Goldacre, Ben;
(2022)
Recording of 'COVID-19 vaccine declined': a cohort study on 57.9 million National Health Service patients' records in situ using OpenSAFELY, England, 8 December 2020 to 25 May 2021.
Eurosurveillance, 27 (33).
ISSN 1560-7917
DOI: https://doi.org/10.2807/1560-7917.ES.2022.27.33.2100885
Davidson, Jennifer A;
Banerjee, Amitava;
Douglas, Ian;
Leyrat, Clémence;
Pebody, Richard;
McDonald, Helen I;
Herrett, Emily;
Forbes, Harriet;
Smeeth, Liam;
Warren-Gash, Charlotte;
(2022)
Primary prevention of acute cardiovascular events by influenza vaccination: an observational study.
European heart journal, 44 (7).
pp. 610-620.
ISSN 0195-668X
DOI: https://doi.org/10.1093/eurheartj/ehac737
Hulme, William J;
Williamson, Elizabeth J;
Green, Amelia CA;
Bhaskaran, Krishnan;
McDonald, Helen I;
Rentsch, Christopher T;
Schultze, Anna;
Tazare, John;
Curtis, Helen J;
Walker, Alex J;
+32 more...
Tomlinson, Laurie A;
Palmer, Tom;
Horne, Elsie MF;
MacKenna, Brian;
Morton, Caroline E;
Mehrkar, Amir;
Morley, Jessica;
Fisher, Louis;
Bacon, Sebastian CJ;
Evans, David;
Inglesby, Peter;
Hickman, George;
Davy, Simon;
Ward, Tom;
Croker, Richard;
Eggo, Rosalind M;
Wong, Angel YS;
Mathur, Rohini;
Wing, Kevin;
Forbes, Harriet;
Grint, Daniel J;
Douglas, Ian J;
Evans, Stephen JW;
Smeeth, Liam;
Bates, Chris;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Sterne, Jonathan AC;
Hernán, Miguel A;
Goldacre, Ben;
(2022)
Comparative effectiveness of ChAdOx1 versus BNT162b2 covid-19 vaccines in health and social care workers in England: cohort study using OpenSAFELY.
BMJ, 378.
e068946-.
DOI: https://doi.org/10.1136/bmj-2021-068946
MacKenna, Brian;
Kennedy, Nicholas A;
Mehrkar, Amir;
Rowan, Anna;
Galloway, James;
Matthewman, Julian;
Mansfield, Kathryn E;
Bechman, Katie;
Yates, Mark;
Brown, Jeremy;
+38 more...
Schultze, Anna;
Norton, Sam;
Walker, Alex J;
Morton, Caroline E;
Harrison, David;
Bhaskaran, Krishnan;
Rentsch, Christopher T;
Williamson, Elizabeth;
Croker, Richard;
Bacon, Seb;
Hickman, George;
Ward, Tom;
Davy, Simon;
Green, Amelia;
Fisher, Louis;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Tazare, John;
Eggo, Rosalind M;
Evans, David;
Inglesby, Peter;
Cockburn, Jonathan;
McDonald, Helen I;
Tomlinson, Laurie A;
Mathur, Rohini;
Wong, Angel YS;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Smeeth, Liam;
Lees, Charlie W;
Evans, Stephen JW;
Goldacre, Ben;
Smith, Catherine H;
Langan, Sinéad M;
(2022)
Risk of severe COVID-19 outcomes associated with immune-mediated inflammatory diseases and immune-modifying therapies: a nationwide cohort study in the OpenSAFELY platform.
The Lancet Rheumatology, 4 (7).
e490-e506.
ISSN 2665-9913
DOI: https://doi.org/10.1016/S2665-9913(22)00098-4
OpenSAFELY Collaborative;
Green, Amelia;
Curtis, Helen;
Hulme, William;
Williamson, Elizabeth;
McDonald, Helen;
Bhaskaran, Krishnan;
Rentsch, Christopher;
Schultze, Anna;
MacKenna, Brian;
+32 more...
Mahalingasivam, Viyaasan;
Tomlinson, Laurie;
Walker, Alex;
Fisher, Louis;
Massey, Jon;
Andrews, Colm;
Hopcroft, Lisa;
Morton, Caroline;
Croker, Richard;
Morley, Jessica;
Mehrkar, Amir;
Bacon, Seb;
Evans, David;
Inglesby, Peter;
Hickman, George;
Ward, Tom;
Davy, Simon;
Mathur, Rohini;
Tazare, John;
Eggo, Rosalind;
Wing, Kevin;
Wong, Angel;
Forbes, Harriet;
Bates, Chris;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian;
Evans, Stephen;
Smeeth, Liam;
Goldacre, Ben;
(2022)
Describing the population experiencing COVID-19 vaccine breakthrough following second vaccination in England: a cohort study from OpenSAFELY.
BMC medicine, 20 (1).
243-.
ISSN 1741-7015
DOI: https://doi.org/10.1186/s12916-022-02422-0
OpenSAFELY Collaborative;
Tazare, John;
Walker, Alex J;
Tomlinson, Laurie A;
Hickman, George;
Rentsch, Christopher T;
Williamson, Elizabeth J;
Bhaskaran, Krishnan;
Evans, David;
Wing, Kevin;
+31 more...
Mathur, Rohini;
Wong, Angel Ys;
Schultze, Anna;
Bacon, Seb;
Bates, Chris;
Morton, Caroline E;
Curtis, Helen J;
Nightingale, Emily;
McDonald, Helen I;
Mehrkar, Amir;
Inglesby, Peter;
Davy, Simon;
MacKenna, Brian;
Cockburn, Jonathan;
Hulme, William J;
Warren-Gash, Charlotte;
Bhate, Ketaki;
Nitsch, Dorothea;
Powell, Emma;
Mulick, Amy;
Forbes, Harriet;
Minassian, Caroline;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Eggo, Rosalind M;
Evans, Stephen Jw;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
(2022)
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19 in England: a descriptive cohort study within the OpenSAFELY platform.
Wellcome open research, 7.
142-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.17735.1
Schultze, Anna;
Nightingale, Emily;
Evans, David;
Hulme, William;
Rosello, Alicia;
Bates, Chris;
Cockburn, Jonathan;
MacKenna, Brian;
Curtis, Helen J;
Morton, Caroline E;
+32 more...
Croker, Richard;
Bacon, Seb;
McDonald, Helen I;
Rentsch, Christopher T;
Bhaskaran, Krishnan;
Mathur, Rohini;
Tomlinson, Laurie A;
Williamson, Elizabeth J;
Forbes, Harriet;
Tazare, John;
Grint, Daniel;
Walker, Alex J;
Inglesby, Peter;
DeVito, Nicholas J;
Mehrkar, Amir;
Hickman, George;
Davy, Simon;
Ward, Tom;
Fisher, Louis;
Green, Amelia Ca;
Wing, Kevin;
Wong, Angel Ys;
McManus, Robert;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen Jw;
Douglas, Ian J;
Smeeth, Liam;
Eggo, Rosalind M;
Goldacre, Ben;
Leon, David A;
(2022)
Mortality among Care Home Residents in England during the first and second waves of the COVID-19 pandemic: an observational study of 4.3 million adults over the age of 65.
The Lancet regional health. Europe, 14.
100295-.
ISSN 2666-7762
DOI: https://doi.org/10.1016/j.lanepe.2021.100295
Tazare, JR;
(2022)
High-dimensional propensity scores for data-driven confounder adjustment in UK electronic health records.
PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04664727
Walker, Jemma L;
Schultze, Anna;
Tazare, John;
Tamborska, Arina;
Singh, Bhagteshwar;
Donegan, Katherine;
Stowe, Julia;
Morton, Caroline E;
Hulme, William J;
Curtis, Helen J;
+27 more...
Williamson, Elizabeth J;
Mehrkar, Amir;
Eggo, Rosalind M;
Rentsch, Christopher T;
Mathur, Rohini;
Bacon, Sebastian;
Walker, Alex J;
Davy, Simon;
Evans, David;
Inglesby, Peter;
Hickman, George;
MacKenna, Brian;
Tomlinson, Laurie;
Ca Green, Amelia;
Fisher, Louis;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Bates, Christopher;
Evans, Stephen Jw;
Solomon, Tom;
Andrews, Nick J;
Douglas, Ian J;
Goldacre, Ben;
Smeeth, Liam;
McDonald, Helen I;
(2022)
Safety of COVID-19 vaccination and acute neurological events: A self-controlled case series in England using the OpenSAFELY platform.
Vaccine, 40 (32).
pp. 4479-4487.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2022.06.010
Wing, Kevin;
Grint, Daniel J;
Mathur, Rohini;
Gibbs, Hamish P;
Hickman, George;
Nightingale, Emily;
Schultze, Anna;
Forbes, Harriet;
Nafilyan, Vahé;
Bhaskaran, Krishnan;
+16 more...
Williamson, Elizabeth;
House, Thomas;
Pellis, Lorenzo;
Herrett, Emily;
Gautam, Nileesa;
Curtis, Helen J;
Rentsch, Christopher T;
Wong, Angel YS;
MacKenna, Brian;
Mehrkar, Amir;
Bacon, Seb;
Douglas, Ian J;
Evans, Stephen JW;
Tomlinson, Laurie;
Goldacre, Ben;
Eggo, Rosalind M;
(2022)
Association between household composition and severe COVID-19 outcomes in older people by ethnicity: an observational cohort study using the OpenSAFELY platform.
International Journal of Epidemiology, 51 (6).
pp. 1745-1760.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyac158
Wong, Angel Ys;
Tomlinson, Laurie;
Brown, Jeremy P;
Elson, William;
Walker, Alex J;
Schultze, Anna;
Morton, Caroline E;
Evans, David;
Inglesby, Peter;
MacKenna, Brian;
+21 more...
Bhaskaran, Krishnan;
Rentsch, Christopher T;
Powell, Emma;
Williamson, Elizabeth;
Croker, Richard;
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Cockburn, Jonathan;
McDonald, Helen I;
Mathur, Rohini;
Wing, Kevin;
Forbes, Harriet;
Eggo, Rosalind M;
Evans, Stephen Jw;
Smeeth, Liam;
Goldacre, Ben;
Douglas, Ian J;
(The OpenSAFELY Collaborative);
(2022)
Association between oral anticoagulants and COVID-19-related outcomes: a population-based cohort study.
The British journal of general practice : the journal of the Royal College of General Practitioners, 72 (720).
e456-e463.
ISSN 0960-1643
DOI: https://doi.org/10.3399/BJGP.2021.0689
Zheng, Bang;
Green, Amelia CA;
Tazare, John;
Curtis, Helen J;
Fisher, Louis;
Nab, Linda;
Schultze, Anna;
Mahalingasivam, Viyaasan;
Parker, Edward PK;
Hulme, William J;
+23 more...
Bacon, Sebastian CJ;
DeVito, Nicholas J;
Bates, Christopher;
Evans, David;
Inglesby, Peter;
Drysdale, Henry;
Davy, Simon;
Cockburn, Jonathan;
Morton, Caroline E;
Hickman, George;
Ward, Tom;
Smith, Rebecca M;
Parry, John;
Hester, Frank;
Harper, Sam;
Mehrkar, Amir;
Eggo, Rosalind M;
Walker, Alex J;
Evans, Stephen JW;
Douglas, Ian J;
MacKenna, Brian;
Goldacre, Ben;
Tomlinson, Laurie A;
(2022)
Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe covid-19 outcomes in patients in the community: observational cohort study with the OpenSAFELY platform.
BMJ (Clinical research ed.), 379.
e071932-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj-2022-071932
Österdahl, Marc F;
Sinnott, Sarah-Jo;
Douglas, Ian;
Clegg, Andrew;
Tomlinson, Laurie;
Wong, Angel;
(2022)
Frailty and rate of fractures in patients initiating antihypertensive medications: a cohort study in primary care.
Drugs and Therapy Perspectives, 38 (1).
pp. 41-50.
ISSN 1172-0360
DOI: https://doi.org/10.1007/s40267-021-00891-6
2021
Bhaskaran, Krishnan;
Bacon, Sebastian;
Evans, Stephen Jw;
Bates, Chris J;
Rentsch, Christopher T;
MacKenna, Brian;
Tomlinson, Laurie;
Walker, Alex J;
Schultze, Anna;
Morton, Caroline E;
+17 more...
Grint, Daniel;
Mehrkar, Amir;
Eggo, Rosalind M;
Inglesby, Peter;
Douglas, Ian J;
McDonald, Helen I;
Cockburn, Jonathan;
Williamson, Elizabeth J;
Evans, David;
Curtis, Helen J;
Hulme, William J;
Parry, John;
Hester, Frank;
Harper, Sam;
Spiegelhalter, David;
Smeeth, Liam;
Goldacre, Ben;
(2021)
Factors associated with deaths due to COVID-19 versus other causes: population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform.
The Lancet regional health. Europe, 6.
100109-.
ISSN 2666-7762
DOI: https://doi.org/10.1016/j.lanepe.2021.100109
Bidulka, Patrick;
O'Neill, Stephen;
Basu, Anirban;
Wilkinson, Samantha;
Silverwood, Richard J;
Charlton, Paul;
Briggs, Andrew;
Adler, Amanda I;
Khunti, Kamlesh;
Tomlinson, Laurie A;
+3 more...
Smeeth, Liam;
Douglas, Ian J;
Grieve, Richard;
(2021)
Protocol for an observational cohort study investigating personalised medicine for intensification of treatment in people with type 2 diabetes mellitus: the PERMIT study.
BMJ Open, 11 (9).
e046912-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2020-046912
Brown, Jeremy P;
Tazare, John R;
Williamson, Elizabeth;
Mansfield, Kathryn E;
Evans, Stephen J;
Tomlinson, Laurie A;
Bhaskaran, Krishnan;
Smeeth, Liam;
Wing, Kevin;
Douglas, Ian J;
(2021)
Proton pump inhibitors and risk of all-cause and cause-specific mortality: A cohort study.
British journal of clinical pharmacology, 87 (8).
pp. 3150-3161.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.14728
Curtis, Helen J;
Inglesby, Peter;
Morton, Caroline E;
MacKenna, Brian;
Green, Amelia;
Hulme, William;
Walker, Alex J;
Morley, Jessica;
Mehrkar, Amir;
Bacon, Seb;
+36 more...
Hickman, George;
Bates, Chris;
Croker, Richard;
Evans, David;
Ward, Tom;
Cockburn, Jonathan;
Davy, Simon;
Bhaskaran, Krishnan;
Schultze, Anna;
Rentsch, Christopher T;
Williamson, Elizabeth J;
Rowan, Anna;
Fisher, Louis;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Drysdale, Henry;
Eggo, Rosalind M;
Wing, Kevin;
Wong, Angel Ys;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
O'Hanlon, Shaun;
Eavis, Alex;
Jarvis, Richard;
Avramov, Dima;
Griffiths, Paul;
Fowles, Aaron;
Parkes, Nasreen;
Douglas, Ian J;
Evans, Stephen Jw;
Smeeth, Liam;
Goldacre, Ben;
(The OpenSAFELY Collaborative);
(The OpenSAFELY Collaborative);
(2021)
Trends and clinical characteristics of COVID-19 vaccine recipients: a federated analysis of 57.9 million patients’ primary care records in situ using OpenSAFELY.
Br J Gen Pract, 72 (714).
e51-e62.
ISSN 0960-1643
DOI: https://doi.org/10.3399/BJGP.2021.0376
Curtis, Helen J;
MacKenna, Brian;
Croker, Richard;
Inglesby, Peter;
Walker, Alex J;
Morley, Jessica;
Mehrkar, Amir;
Morton, Caroline E;
Bacon, Seb;
Hickman, George;
+26 more...
Bates, Chris;
Evans, David;
Ward, Tom;
Cockburn, Jonathan;
Davy, Simon;
Bhaskaran, Krishnan;
Schultze, Anna;
Rentsch, Christopher T;
Williamson, Elizabeth J;
Hulme, William J;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Drysdale, Henry;
Eggo, Rosalind M;
Wing, Kevin;
Wong, Angel Ys;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen Jw;
Douglas, Ian J;
Smeeth, Liam;
Goldacre, Ben;
(The OpenSAFELY Collaborative);
The OpenSAFELY Collaborative;
(2021)
OpenSAFELY NHS Service Restoration Observatory 1: primary care clinical activity in England during the first wave of COVID-19.
The British journal of general practice : the journal of the Royal College of General Practitioners, 72 (714).
e63-e74.
ISSN 0960-1643
DOI: https://doi.org/10.3399/BJGP.2021.0380
Forbes, Harriet;
Morton, Caroline E;
Bacon, Seb;
McDonald, Helen I;
Minassian, Caroline;
Brown, Jeremy P;
Rentsch, Christopher T;
Mathur, Rohini;
Schultze, Anna;
DeVito, Nicholas J;
+25 more...
MacKenna, Brian;
Hulme, William J;
Croker, Richard;
Walker, Alex J;
Williamson, Elizabeth J;
Bates, Chris;
Mehrkar, Amir;
Curtis, Helen J;
Evans, David;
Wing, Kevin;
Inglesby, Peter;
Drysdale, Henry;
Wong, Angel YS;
Cockburn, Jonathan;
McManus, Robert;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Smeeth, Liam;
Evans, Stephen JW;
Bhaskaran, Krishnan;
Eggo, Rosalind M;
Goldacre, Ben;
Tomlinson, Laurie A;
(2021)
Association between living with children and outcomes from covid-19: OpenSAFELY cohort study of 12 million adults in England.
BMJ: British Medical Journal, 372.
n628-.
ISSN 1759-2151
DOI: https://doi.org/10.1136/bmj.n628
Grint, Daniel J;
Wing, Kevin;
Houlihan, Catherine;
Gibbs, Hamish P;
Evans, Stephen JW;
Williamson, Elizabeth;
McDonald, Helen I;
Bhaskaran, Krishnan;
Evans, David;
Walker, Alex J;
+27 more...
Hickman, George;
Nightingale, Emily;
Schultze, Anna;
Rentsch, Christopher T;
Bates, Chris;
Cockburn, Jonathan;
Curtis, Helen J;
Morton, Caroline E;
Bacon, Sebastian;
Davy, Simon;
Wong, Angel YS;
Mehrkar, Amir;
Tomlinson, Laurie;
Douglas, Ian J;
Mathur, Rohini;
MacKenna, Brian;
Ingelsby, Peter;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
DeVito, Nicholas J;
Hulme, Will;
Tazare, John;
Smeeth, Liam;
Goldacre, Ben;
Eggo, Rosalind M;
(2021)
Severity of Severe Acute Respiratory System Coronavirus 2 (SARS-CoV-2) Alpha Variant (B.1.1.7) in England.
Clinical infectious diseases, 75 (1).
e1120-e1127.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/ciab754
Grint, Daniel J;
Wing, Kevin;
Williamson, Elizabeth;
McDonald, Helen I;
Bhaskaran, Krishnan;
Evans, David;
Evans, Stephen Jw;
Walker, Alex J;
Hickman, George;
Nightingale, Emily;
+26 more...
Schultze, Anna;
Rentsch, Christopher T;
Bates, Chris;
Cockburn, Jonathan;
Curtis, Helen J;
Morton, Caroline E;
Bacon, Sebastian;
Davy, Simon;
Wong, Angel Ys;
Mehrkar, Amir;
Tomlinson, Laurie;
Douglas, Ian J;
Mathur, Rohini;
Blomquist, Paula;
MacKenna, Brian;
Ingelsby, Peter;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
DeVito, Nicholas J;
Hulme, Will;
Tazare, John;
Goldacre, Ben;
Smeeth, Liam;
Eggo, Rosalind M;
(2021)
Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February.
Eurosurveillance, 26 (11).
pp. 10-15.
ISSN 1025-7917
DOI: https://doi.org/10.2807/1560-7917.ES.2021.26.11.2100256
Iwagami, Masao;
Qizilbash, Nawab;
Gregson, John;
Douglas, Ian;
Johnson, Michelle;
Pearce, Neil;
Evans, Stephen;
Pocock, Stuart;
(2021)
Blood cholesterol and risk of dementia in more than 1·8 million people over two decades: a retrospective cohort study.
The Lancet Healthy Longevity, 2 (8).
e498-e506.
ISSN 2666-7568
DOI: https://doi.org/10.1016/S2666-7568(21)00150-1
Mathur, Rohini;
Rentsch, Christopher T;
Morton, Caroline E;
Hulme, William J;
Schultze, Anna;
MacKenna, Brian;
Eggo, Rosalind M;
Bhaskaran, Krishnan;
Wong, Angel YS;
Williamson, Elizabeth J;
+27 more...
Forbes, Harriet;
Wing, Kevin;
McDonald, Helen I;
Bates, Chris;
Bacon, Seb;
Walker, Alex J;
Evans, David;
Inglesby, Peter;
Mehrkar, Amir;
Curtis, Helen J;
DeVito, Nicholas J;
Croker, Richard;
Drysdale, Henry;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Tomlinson, Laurie;
Evans, Stephen JW;
Grieve, Richard;
Harrison, David;
Rowan, Kathy;
Khunti, Kamlesh;
Chaturvedi, Nishi;
Smeeth, Liam;
Goldacre, Ben;
(2021)
Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform.
Lancet (London, England), 397 (10286).
pp. 1711-1724.
ISSN 0140-6736
DOI: https://doi.org/10.1016/s0140-6736(21)00634-6
OpenSAFELY Collaborative;
Curtis, Helen J;
MacKenna, Brian;
Walker, Alex J;
Croker, Richard;
Mehrkar, Amir;
Morton, Caroline;
Bacon, Seb;
Hickman, George;
Inglesby, Peter;
+22 more...
Bates, Chris;
Evans, David;
Ward, Tom;
Cockburn, Jonathan;
Davy, Simon;
Bhaskaran, Krishnan;
Schultze, Anna;
Rentsch, Christopher T;
Williamson, Elizabeth;
Hulme, William;
Tomlinson, Laurie;
Mathur, Rohini;
Drysdale, Henry;
Eggo, Rosalind M;
Wong, Angel Yun;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian;
Smeeth, Liam;
Goldacre, Ben;
The OpenSAFELY Collaborative;
(2021)
OpenSAFELY: impact of national guidance on switching anticoagulant therapy during COVID-19 pandemic.
Open heart, 8 (2).
e001784-e001784.
ISSN 2053-3624
DOI: https://doi.org/10.1136/openhrt-2021-001784
OpenSAFELY Collaborative;
Wong, Angel YS;
Tomlinson, Laurie A;
Brown, Jeremy P;
Elson, William;
Walker, Alex J;
Schultze, Anna;
Morton, Caroline E;
Evans, David;
Inglesby, Peter;
+21 more...
MacKenna, Brian;
Bhaskaran, Krishnan;
Rentsch, Christopher T;
Powell, Emma;
Williamson, Elizabeth;
Croker, Richard;
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Cockburn, Jonathan;
McDonald, Helen I;
Mathur, Rohini;
Wing, Kevin;
Forbes, Harriet;
Eggo, Rosalind M;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
Douglas, Ian J;
OpenSAFELY Collaborative;
(2021)
Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants: population-based cohort study.
Journal of hematology & oncology, 14 (1).
172-.
ISSN 1756-8722
DOI: https://doi.org/10.1186/s13045-021-01185-0
Powell, Emma Maud;
Douglas, Ian J;
Gungabissoon, Usha;
Smeeth, Liam;
Wing, Kevin;
(2021)
Real-world effects of medications for stroke prevention in atrial fibrillation: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results.
BMJ open, 11 (4).
e042947-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2020-042947
Prats-Uribe, Albert;
Kolovos, Spyros;
Berencsi, Klara;
Carr, Andrew;
Judge, Andrew;
Silman, Alan;
Arden, Nigel;
Petersen, Irene;
Douglas, Ian J;
Wilkinson, J Mark;
+8 more...
Murray, David;
Valderas, Jose M;
Beard, David J;
Lamb, Sarah E;
Ali, M Sanni;
Pinedo-Villanueva, Rafael;
Strauss, Victoria Y;
Prieto-Alhambra, Daniel;
(2021)
Unicompartmental compared with total knee replacement for patients with multimorbidities: a cohort study using propensity score stratification and inverse probability weighting.
Health technology assessment (Winchester, England), 25 (66).
pp. 1-126.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta25660
Rentsch, Christopher T;
Beckman, Joshua A;
Tomlinson, Laurie;
Gellad, Walid F;
Alcorn, Charles;
Kidwai-Khan, Farah;
Skanderson, Melissa;
Brittain, Evan;
King, Joseph T;
Ho, Yuk-Lam;
+13 more...
Eden, Svetlana;
Kundu, Suman;
Lann, Michael F;
Greevy, Robert A;
Ho, P Michael;
Heidenreich, Paul A;
Jacobson, Daniel A;
Douglas, Ian J;
Tate, Janet P;
Evans, Stephen JW;
Atkins, David;
Justice, Amy C;
Freiberg, Matthew S;
(2021)
Early initiation of prophylactic anticoagulation for prevention of coronavirus disease 2019 mortality in patients admitted to hospital in the United States: cohort study.
BMJ, 372.
n311-.
DOI: https://doi.org/10.1136/bmj.n311
Rentsch, Christopher T;
DeVito, Nicholas J;
MacKenna, Brian;
Morton, Caroline E;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Schultze, Anna;
Hulme, William J;
Croker, Richard;
Walker, Alex J;
+23 more...
Williamson, Elizabeth J;
Bates, Chris;
Bacon, Seb;
Mehrkar, Amir;
Curtis, Helen J;
Evans, David;
Wing, Kevin;
Inglesby, Peter;
Mathur, Rohini;
Drysdale, Henry;
Wong, Angel YS;
McDonald, Helen I;
Cockburn, Jonathan;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Smeeth, Liam;
Douglas, Ian J;
Dixon, William G;
Evans, Stephen JW;
Tomlinson, Laurie;
Goldacre, Ben;
(2021)
Hydroxychloroquine treatment does not reduce COVID-19 mortality; underdosing to the wrong patients? - Authors' reply.
The Lancet Rheumatology, 3 (3).
e172-e173.
ISSN 2665-9913
DOI: https://doi.org/10.1016/S2665-9913(21)00030-8
Schultze, Anna;
Douglas, Ian;
(2021)
COVID-19 and inhaled corticosteroids-another piece in an expanding puzzle.
LANCET RESPIRATORY MEDICINE, 9 (7).
pp. 674-675.
ISSN 2213-2600
DOI: https://doi.org/10.1016/S2213-2600(21)00076-X
Tazare, John;
Walker, Alex J;
Tomlinson, Laurie;
Hickman, George;
Rentsch, Christopher T;
Williamson, Elizabeth J;
Bhaskaran, Krishnan;
Evans, David;
Wing, Kevin;
Mathur, Rohini;
+30 more...
Wong, Angel YS;
Schultze, Anna;
Bacon, Seb;
Bates, Chris;
Morton, Caroline E;
Curtis, Helen J;
Nightingale, Emily;
McDonald, Helen I;
Mehrkar, Amir;
Inglesby, Peter;
Davy, Simon;
MacKenna, Brian;
Cockburn, Jonathan;
Hulme, William J;
Warren-Gash, Charlotte;
Bhate, Ketaki;
Nitsch, Dorothea;
Powell, Emma;
Mulick, Amy;
Forbes, Harriet;
Minassian, Caroline;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Eggo, Rosalind M;
Evans, Stephen JW;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
(2021)
Rates of serious clinical outcomes in survivors of hospitalisation with COVID-19: a descriptive cohort study within the OpenSAFELY platform.
MedRxiv.
DOI: https://doi.org/10.1101/2021.01.22.21250304
Walker, Alex J;
MacKenna, Brian;
Inglesby, Peter;
Tomlinson, Laurie;
Rentsch, Christopher T;
Curtis, Helen J;
Morton, Caroline E;
Morley, Jessica;
Mehrkar, Amir;
Bacon, Seb;
+31 more...
Hickman, George;
Bates, Chris;
Croker, Richard;
Evans, David;
Ward, Tom;
Cockburn, Jonathan;
Davy, Simon;
Bhaskaran, Krishnan;
Schultze, Anna;
Williamson, Elizabeth J;
Hulme, William J;
McDonald, Helen I;
Mathur, Rohini;
Eggo, Rosalind M;
Wing, Kevin;
Wong, Angel Ys;
Forbes, Harriet;
Tazare, John;
Parry, John;
Hester, Frank;
Harper, Sam;
O'Hanlon, Shaun;
Eavis, Alex;
Jarvis, Richard;
Avramov, Dima;
Griffiths, Paul;
Fowles, Aaron;
Parkes, Nasreen;
Douglas, Ian J;
Evans, Stephen Jw;
(The OpenSAFELY Collaborative);
(2021)
Clinical coding of long COVID in English primary care: a federated analysis of 58 million patient records in situ using OpenSAFELY.
British Journal of General Practice, 71 (712).
e806-e814.
ISSN 0960-1643
DOI: https://doi.org/10.3399/BJGP.2021.0301
Walker, Alex J;
Tazare, John;
Hickman, George;
Rentsch, Christopher T;
Williamson, Elizabeth J;
Bhaskaran, Krishnan;
Evans, David;
Wing, Kevin;
Mathur, Rohini;
Wong, Angel YS;
+24 more...
Schultze, Anna;
Bacon, Sebastian CJ;
Bates, Chris;
Morton, Caroline E;
Curtis, Helen J;
Nightingale, Emily;
McDonald, Helen I;
Mehrkar, Amir;
Inglesby, Peter;
MacKenna, Brian;
Cockburn, Jonathan;
Hulme, William J;
Forbes, Harriet;
Minassian, Caroline;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Eggo, Rosalind M;
Evans, Stephen JW;
Smeeth, Liam;
Douglas, Ian J;
Tomlinson, Laurie;
Goldacre, Ben;
(2021)
Changes in the rate of cardiometabolic and pulmonary events during the COVID-19 pandemic.
medRxiv preprint.
DOI: https://doi.org/10.1101/2021.02.17.21251812
Walker, Jemma L;
Grint, Daniel J;
Strongman, Helen;
Eggo, Rosalind M;
Peppa, Maria;
Minassian, Caroline;
Mansfield, Kathryn E;
Rentsch, Christopher T;
Douglas, Ian J;
Mathur, Rohini;
+8 more...
Wong, Angel YS;
Quint, Jennifer K;
Andrews, Nick;
Bernal, Jamie Lopez;
Scott, J Anthony;
Ramsay, Mary;
Smeeth, Liam;
McDonald, Helen I;
(2021)
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records.
BMC public health, 21 (1).
484-.
ISSN 1471-2458
DOI: https://doi.org/10.1186/s12889-021-10427-2
Williamson, Elizabeth J;
McDonald, Helen I;
Bhaskaran, Krishnan;
Walker, Alex J;
Bacon, Sebastian;
Davy, Simon;
Schultze, Anna;
Tomlinson, Laurie;
Bates, Chris;
Ramsay, Mary;
+26 more...
Curtis, Helen J;
Forbes, Harriet;
Wing, Kevin;
Minassian, Caroline;
Tazare, John;
Morton, Caroline E;
Nightingale, Emily;
Mehrkar, Amir;
Evans, Dave;
Inglesby, Peter;
MacKenna, Brian;
Cockburn, Jonathan;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel YS;
Eggo, Rosalind M;
Hulme, Will;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
Kuper, Hannah;
(2021)
OpenSAFELY: Risks of COVID-19 hospital admission and death for people with learning disabilities - a cohort study.
medRxiv preprint.
DOI: https://doi.org/10.1101/2021.03.08.21253112
Williamson, Elizabeth J;
McDonald, Helen I;
Bhaskaran, Krishnan;
Walker, Alex J;
Bacon, Sebastian;
Davy, Simon;
Schultze, Anna;
Tomlinson, Laurie;
Bates, Chris;
Ramsay, Mary;
+26 more...
Curtis, Helen J;
Forbes, Harriet;
Wing, Kevin;
Minassian, Caroline;
Tazare, John;
Morton, Caroline E;
Nightingale, Emily;
Mehrkar, Amir;
Evans, Dave;
Inglesby, Peter;
MacKenna, Brian;
Cockburn, Jonathan;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel YS;
Eggo, Rosalind M;
Hulme, William;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
Kuper, Hannah;
(2021)
Risks of covid-19 hospital admission and death for people with learning disability: population based cohort study using the OpenSAFELY platform.
BMJ (Clinical research ed.), 374.
n1592-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.n1592
Williamson, Elizabeth J;
Tazare, John;
Bhaskaran, Krishnan;
McDonald, Helen I;
Walker, Alex J;
Tomlinson, Laurie;
Wing, Kevin;
Bacon, Sebastian;
Bates, Chris;
Curtis, Helen J;
+34 more...
Forbes, Harriet;
Minassian, Caroline;
Morton, Caroline E;
Nightingale, Emily;
Mehrkar, Amir;
Evans, Dave;
Nicholson, Brian D;
Leon, Dave;
Inglesby, Peter;
MacKenna, Brian;
Davies, Nicholas G;
DeVito, Nicholas J;
Drysdale, Henry;
Cockburn, Jonathan;
Hulme, Will;
Morley, Jess;
Douglas, Ian;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel;
Schultze, Anna;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Grieve, Richard;
Harrison, David A;
Steyerberg, Ewout W;
Eggo, Rosalind M;
Diaz-Ordaz, Karla;
Keogh, Ruth;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
(2021)
Predicting COVID-19 related death using the OpenSAFELY platform.
medRxiv preprint.
DOI: https://doi.org/10.1101/2021.02.25.21252433
Wing, Kevin;
Williamson, Elizabeth;
Carpenter, James R;
Wise, Lesley;
Schneeweiss, Sebastian;
Smeeth, Liam;
Quint, Jennifer K;
Douglas, Ian;
(2021)
Medications for chronic obstructive pulmonary disease: a historical non-interventional cohort study with validation against RCT results.
Health technology assessment (Winchester, England), 25 (51).
pp. 1-70.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta25510
Wong, Angel Ys;
MacKenna, Brian;
Morton, Caroline E;
Schultze, Anna;
Walker, Alex J;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Rentsch, Christopher T;
Williamson, Elizabeth;
Drysdale, Henry;
+23 more...
Croker, Richard;
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
Cockburn, Jonathan;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Wing, Kevin;
Forbes, Harriet;
Eggo, Rosalind M;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen Jw;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
OpenSAFELY Collaborative;
(2021)
Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19: an OpenSAFELY cohort analysis based on two cohorts.
Annals of the rheumatic diseases, 80 (7).
pp. 943-951.
ISSN 0003-4967
DOI: https://doi.org/10.1136/annrheumdis-2020-219517
2020
Bidulka, Patrick;
Iwagami, Masao;
Mansfield, Kathryn E;
Kalogirou, Fotini;
Wong, Angel YS;
Douglas, Ian J;
Smeeth, Liam;
Summers, Charlotte;
Tomlinson, Laurie A;
(2020)
Comparisons of Staphylococcus aureus infection and other outcomes between users of angiotensin-converting-enzyme inhibitors and angiotensin II receptor blockers: lessons for COVID-19 from a nationwide cohort study.
Wellcome Open Research, 5.
77-.
DOI: https://doi.org/10.12688/wellcomeopenres.15873.1
Boddington, Nicola L;
Charlett, Andre;
Elgohari, Suzanne;
Walker, Jemma L;
Mcdonald, Helen;
Byers, Chloe;
Coughlan, Laura;
Garcia Vilaplana, Tatiana;
Whillock, Rosie;
Sinnathamby, Mary;
+22 more...
Panagiotopoulos, Nikolaos;
Letley, Louise;
MacDonald, Pauline;
Vivancos, Roberto;
Edeghere, Obaghe;
Shingleton, Joseph;
Bennett, Emma;
Grint, Daniel J;
Strongman, Helen;
Mansfield, Kathryn E;
Rentsch, Christopher;
Minassian, Caroline;
Douglas, Ian J;
Mathur, Rohini;
Peppa, Maria;
Cottrell, Simon;
McMenamin, Jim;
Zambon, Maria;
Ramsay, Mary;
Dabrera, Gavin;
Saliba, Vanessa;
Lopez Bernal, Jamie;
(2020)
COVID-19 in Great Britain: epidemiological and clinical characteristics of the first few hundred (FF100) cases: a descriptive case series and case control analysis.
medRxiv preprint.
DOI: https://doi.org/10.1101/2020.05.18.20086157
Item availability may be restricted.
Curtis, Helen J;
MacKenna, Brian;
Walker, Alex J;
Croker, Richard;
Mehrkar, Amir;
Morton, Caroline E;
Bacon, Seb;
Hickman, George;
Inglesby, Peter;
Bates, Chris;
+24 more...
Evans, David;
Ward, Tom;
Cockburn, Jonathan;
Davy, Simon;
Bhaskaran, Krishnan;
Schultze, Anna;
Rentsch, Christopher T;
Williamson, Elizabeth;
Hulme, William;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Drysdale, Henry;
Eggo, Rosalind M;
Wing, Kevin;
Wong, Angel YS;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen JW;
Douglas, Ian J;
Smeeth, Liam;
Goldacre, Ben;
(2020)
OpenSAFELY: impact of national guidance on switching from warfarin to direct oral anticoagulants (DOACs) in early phase of COVID-19 pandemic in England.
MedRxiv.
DOI: https://doi.org/10.1101/2020.12.03.20243535
Dedman, Daniel;
Cabecinha, Melissa;
Williams, Rachael;
Evans, Stephen JW;
Bhaskaran, Krishnan;
Douglas, Ian J;
(2020)
Approaches for combining primary care electronic health record data from multiple sources: a systematic review of observational studies.
BMJ OPEN, 10 (10).
e037405-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2020-037405
Forbes, Harriet;
Douglas, Ian;
Finn, Adam;
Breuer, Judith;
Bhaskaran, Krishnan;
Smeeth, Liam;
Packer, Simon;
Langan, Sinéad M;
Mansfield, Kathryn E;
Marlow, Robin;
+2 more...
Whitaker, Heather;
Warren-Gash, Charlotte;
(2020)
Risk of herpes zoster after exposure to varicella to explore the exogenous boosting hypothesis: self controlled case series study using UK electronic healthcare data.
BMJ-BRITISH MEDICAL JOURNAL, 368.
l6987-.
ISSN 1756-1833
DOI: https://doi.org/10.1136/bmj.l6987
Forbes, Harriet;
Morton, Caroline E;
Bacon, Seb;
McDonald, Helen I;
Minassian, Caroline;
Brown, Jeremy P;
Rentsch, Christopher T;
Mathur, Rohini;
Schultze, Anna;
DeVito, Nicholas J;
+25 more...
MacKenna, Brian;
Hulme, William J;
Croker, Richard;
Walker, Alex J;
Williamson, Elizabeth J;
Bates, Chris;
Mehrkar, Amir;
Curtis, Helen J;
Evans, David;
Wing, Kevin;
Inglesby, Peter;
Drysdale, Henry;
Wong, Angel YS;
Cockburn, Jonathan;
McManus, Robert;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Smeeth, Liam;
Evans, Stephen JW;
Bhaskaran, Krishnan;
Eggo, Rosalind M;
Goldacre, Ben;
Tomlinson, Laurie A;
(2020)
Association between living with children and outcomes from COVID-19: an OpenSAFELY cohort study of 12 million adults in England.
medRxiv preprint.
DOI: https://doi.org/10.1101/2020.11.01.20222315
Mathur, Rohini;
Farmer, Ruth E;
Eastwood, Sophie V;
Chaturvedi, Nish;
Douglas, Ian;
Smeeth, Liam;
(2020)
Ethnic disparities in initiation and intensification of diabetes treatment in adults with type 2 diabetes in the UK, 1990-2017: A cohort study.
PLoS medicine, 17 (5).
e1003106-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1003106
Mathur, Rohini;
Rentsch, Christopher T;
Morton, Caroline E;
Hulme, William J;
Schultze, Anna;
MacKenna, Brian;
Eggo, Rosalind M;
Bhaskaran, Krishnan;
Wong, Angel YS;
Williamson, Elizabeth J;
+28 more...
Forbes, Harriet;
Wing, Kevin;
McDonald, Helen I;
Bates, Chris;
Bacon, Seb;
Walker, Alex J;
Evans, David;
Inglesby, Peter;
Mehrkar, Amir;
Curtis, Helen J;
DeVito, Nicholas J;
Croker, Richard;
Drysdale, Henry;
Cockburn, Jonathan;
Parry, John;
Hester, Frank;
Harper, Sam;
Douglas, Ian J;
Tomlinson, Laurie;
Evans, Stephen JW;
Grieve, Richard;
Harrison, David;
Rowan, Kathy;
Khunti, Kamlesh;
Chaturvedi, Nishi;
Smeeth, Liam;
Goldacre, Ben;
OpenSAFELY Collaborative;
(2020)
Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England: an observational cohort study using the OpenSAFELY platform.
MedRxiv, 397 (10286).
pp. 1711-1724.
DOI: https://doi.org/10.1016/S0140-6736(21)00634-6
Rentsch, Christopher T;
Beckman, Joshua A;
Tomlinson, Laurie;
Gellad, Walid F;
Alcorn, Charles;
Kidwai-Khan, Farah;
Skanderson, Melissa;
Brittain, Evan;
King, Joseph T;
Ho, Yuk-Lam;
+13 more...
Eden, Svetlana;
Kundu, Suman;
Lann, Michael F;
Greevy, Robert A;
Ho, P Michael;
Heidenreich, Paul A;
Jacobson, Daniel A;
Douglas, Ian J;
Tate, Janet P;
Evans, Stephen Jw;
Atkins, David;
Justice, Amy C;
Freiberg, Matthew S;
(2020)
Early initiation of prophylactic anticoagulation for prevention of COVID-19 mortality: a nationwide cohort study of hospitalized patients in the United States.
medRxiv.
DOI: https://doi.org/10.1101/2020.12.09.20246579
Rentsch, Christopher T;
DeVito, Nicholas J;
MacKenna, Brian;
Morton, Caroline E;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Schultze, Anna;
Hulme, William J;
Croker, Richard;
Walker, Alex J;
+23 more...
Williamson, Elizabeth J;
Bates, Chris;
Bacon, Seb;
Mehrkar, Amir;
Curtis, Helen J;
Evans, David;
Wing, Kevin;
Inglesby, Peter;
Mathur, Rohini;
Drysdale, Henry;
Wong, Angel YS;
McDonald, Helen I;
Cockburn, Jonathan;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Smeeth, Liam;
Douglas, Ian J;
Dixon, William G;
Evans, Stephen JW;
Tomlinson, Laurie;
Goldacre, Ben;
(2020)
Effect of pre-exposure use of hydroxychloroquine on COVID-19 mortality: a population-based cohort study in patients with rheumatoid arthritis or systemic lupus erythematosus using the OpenSAFELY platform.
The Lancet Rheumatology, 3 (1).
e19-e27.
ISSN 2665-9913
DOI: https://doi.org/10.1016/S2665-9913(20)30378-7
Rentsch, Christopher T;
DeVito, Nicholas J;
MacKenna, Brian;
Morton, Caroline E;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Schultze, Anna;
J Hulme, William;
Croker, Richard;
Walker, Alex J;
+23 more...
Williamson, Elizabeth J;
Bates, Chris;
Bacon, Seb;
Mehrkar, Amir;
Curtis, Helen J;
Evans, David;
Wing, Kevin;
Inglesby, Peter;
Mathur, Rohini;
Drysdale, Henry;
Wong, Angel YS;
McDonald, Helen I;
Cockburn, Jonathan;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Smeeth, Liam;
Douglas, Ian J;
Dixon, William G;
Evans, Stephen JW;
Tomlinson, Laurie;
Goldacre, Ben;
(2020)
Hydroxychloroquine for prevention of COVID-19 mortality: a population-based cohort study.
lancet rheumatology, 3 (1).
E19-E27.
DOI: https://doi.org/10.1101/2020.09.04.20187781
Requena, Gema;
Douglas, Ian J;
Huerta, Consuelo;
de Abajo, Francisco;
(2020)
Impact of pre-exposure time bias in self-controlled case series when the event conditions the exposure: Hip/femur fracture and use of benzodiazepines as a case study.
Pharmacoepidemiology and Drug Safety, 29 (4).
pp. 388-395.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.4959
Schultze, Anna;
Walker, Alex J;
MacKenna, Brian;
Morton, Caroline E;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Rentsch, Christopher T;
Williamson, Elizabeth;
Drysdale, Henry;
Croker, Richard;
+22 more...
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
Cockburn, Jonathan;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Wing, Kevin;
Wong, Angel YS;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen JW;
Quint, Jennifer;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
(2020)
Inhaled corticosteroid use and risk COVID-19 related death among 966,461 patients with COPD or asthma: an OpenSAFELY analysis.
medRxiv preprint.
DOI: https://doi.org/10.1101/2020.06.19.20135491
Schultze, Anna;
Walker, Alex J;
MacKenna, Brian;
Morton, Caroline E;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Rentsch, Christopher T;
Williamson, Elizabeth;
Drysdale, Henry;
Croker, Richard;
+23 more...
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
Cockburn, Jonathan;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Wing, Kevin;
Wong, Angel YS;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen JW;
Quint, Jennifer;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
OpenSAFELY Collaborative;
OpenSAFELY Collaborative;
(2020)
Risk of COVID-19-related death among patients with chronic obstructive pulmonary disease or asthma prescribed inhaled corticosteroids: an observational cohort study using the OpenSAFELY platform.
LANCET RESPIRATORY MEDICINE, 8 (11).
pp. 1106-1120.
ISSN 2213-2600
DOI: https://doi.org/10.1016/S2213-2600(20)30415-X
Sinnott, Sarah-Jo;
Douglas, Ian J;
Smeeth, Liam;
Williamson, Elizabeth;
Tomlinson, Laurie A;
(2020)
First line drug treatment for hypertension and reductions in blood pressure according to age and ethnicity: cohort study in UK primary care.
BMJ-BRITISH MEDICAL JOURNAL, 371.
m4080-.
ISSN 1756-1833
DOI: https://doi.org/10.1136/bmj.m4080
Tazare, John;
Smeeth, Liam;
Evans, Stephen JW;
Williamson, Elizabeth;
Douglas, Ian J;
(2020)
Implementing high-dimensional propensity score principles to improve confounder adjustment in UK electronic health records.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, 29 (11).
pp. 1373-1381.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.5121
Tazare, John;
Wyss, Richard;
Franklin, Jessica M;
Smeeth, Liam;
Evans, Stephen JW;
Wang, Shirley V;
Schneeweiss, Sebastian;
Douglas, Ian J;
Williamson, Elizabeth;
Gagne, Joshua J;
(2020)
Transparency of high-dimensional propensity score analyses: Guidance for diagnostics and reporting.
In: CPE All Access 2020.
DOI: https://doi.org/10.1002/pds.5412
Walker, Jemma L;
Grint, Daniel J;
Strongman, Helen;
Eggo, Rosalind M;
Peppa, Maria;
Minassian, Caroline;
Mansfield, Kathryn E;
Rentsch, Christopher T;
Douglas, Ian J;
Mathur, Rohini;
+8 more...
Wong, Angel YS;
Quint, Jennifer K;
Andrews, Nick;
Bernal, Jamie Lopez;
Scott, J Anthony;
Ramsay, Mary;
Smeeth, Liam;
McDonald, Helen;
(2020)
UK prevalence of underlying conditions which increase the risk of severe COVID-19 disease: a point prevalence study using electronic health records.
MedRxiv.
DOI: https://doi.org/10.1101/2020.08.24.20179192
Wilkinson, Samantha;
Williamson, Elizabeth;
Pokrajac, Ana;
Fogarty, Damian;
Stirnadel-Farrant, Heide;
Smeeth, Liam;
Douglas, Ian J;
Tomlinson, Laurie A;
(2020)
Comparative effects of sulphonylureas, dipeptidyl peptidase-4 inhibitors and sodium-glucose co-transporter-2 inhibitors added to metformin monotherapy: a propensity-score matched cohort study in UK primary care.
Diabetes, obesity & metabolism, 22 (5).
pp. 847-856.
ISSN 1462-8902
DOI: https://doi.org/10.1111/dom.13970
Williamson, Elizabeth J;
Tazare, John;
Bhaskaran, Krishnan;
Walker, Alex J;
McDonald, Helen I;
Tomlinson, Laurie A;
Bacon, Sebastian;
Bates, Chris;
Curtis, Helen J;
Forbes, Harriet;
+32 more...
Minassian, Caroline;
Morton, Caroline E;
Nightingale, Emily;
Mehrkar, Amir;
Evans, Dave;
Nicholson, Brian D;
Leon, David;
Inglesby, Peter;
MacKenna, Brian;
Cockburn, Jonathan;
Davies, Nicholas G;
Hulme, Will J;
Morley, Jessica;
Douglas, Ian J;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel;
Schultze, Anna;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Perera, Rafael;
Grieve, Richard;
Harrison, David;
Steyerberg, Ewout;
Eggo, Rosalind M;
Diaz-Ordaz, Karla;
Keogh, Ruth;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
(2020)
Study protocol: Comparison of different risk prediction modelling approaches for COVID-19 related death using the OpenSAFELY platform.
Wellcome Open Research, 5.
p. 243.
DOI: https://doi.org/10.12688/wellcomeopenres.16353.1
Williamson, Elizabeth J;
Walker, Alex J;
Bhaskaran, Krishnan;
Bacon, Seb;
Bates, Chris;
Morton, Caroline E;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
+20 more...
Cockburn, Jonathan;
McDonald, Helen I;
MacKenna, Brian;
Tomlinson, Laurie;
Douglas, Ian J;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel YS;
Grieve, Richard;
Harrison, David;
Forbes, Harriet;
Schultze, Anna;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Perera, Rafael;
Evans, Stephen JW;
Smeeth, Liam;
Goldacre, Ben;
(2020)
Factors associated with COVID-19-related death using OpenSAFELY.
Nature, 584 (7821).
pp. 430-436.
ISSN 0028-0836
DOI: https://doi.org/10.1038/s41586-020-2521-4
Williamson, Elizabeth;
Walker, Alex J;
Bhaskaran, Krishnan;
Bacon, Seb;
Bates, Chris;
Morton, Caroline E;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
+20 more...
Cockburn, Jonathan;
McDonald, Helen I;
MacKenna, Brian;
Tomlinson, Laurie;
Douglas, Ian J;
Rentsch, Christopher T;
Mathur, Rohini;
Wong, Angel;
Grieve, Richard;
Harrison, David;
Forbes, Harriet;
Schultze, Anna;
Croker, Richard;
Parry, John;
Hester, Frank;
Harper, Sam;
Perera, Raf;
Evans, Stephen;
Smeeth, Liam;
Goldacre, Ben;
(2020)
OpenSAFELY: factors associated with COVID-19-related hospital death in the linked electronic health records of 17 million adult NHS patients.
MedRxiv.
DOI: https://doi.org/10.1101/2020.05.06.20092999
Item availability may be restricted.
Wing, Kevin;
Williamson, Elizabeth;
Carpenter, James R;
Wise, Lesley;
Schneeweiss, Sebastian;
Smeeth, Liam;
Quint, Jennifer K;
Douglas, Ian;
(2020)
Real world effects of COPD medications: a cohort study with validation against results from randomised controlled trials.
The European respiratory journal, 57 (3).
p. 2001586.
ISSN 0903-1936
DOI: https://doi.org/10.1183/13993003.01586-2020
Wong, Angel YS;
MacKenna, Brian;
Morton, Caroline E;
Schultze, Anna;
Walker, Alex J;
Bhaskaran, Krishnan;
Brown, Jeremy P;
Rentsch, Christopher T;
Williamson, Elizabeth;
Drysdale, Henry;
+21 more...
Croker, Richard;
Bacon, Seb;
Hulme, William;
Bates, Chris;
Curtis, Helen J;
Mehrkar, Amir;
Evans, David;
Inglesby, Peter;
Cockburn, Jonathan;
McDonald, Helen I;
Tomlinson, Laurie;
Mathur, Rohini;
Wing, Kevin;
Forbes, Harriet;
Parry, John;
Hester, Frank;
Harper, Sam;
Evans, Stephen JW;
Smeeth, Liam;
Douglas, Ian J;
Goldacre, Ben;
(2020)
OpenSAFELY: Do adults prescribed non-steroidal anti-inflammatory drugs have an increased risk of death from COVID-19?
medRxiv preprint.
2020.08.12.20171405-.
DOI: https://doi.org/10.1101/2020.08.12.20171405
Item availability may be restricted.
2019
Bloom, Chloe I;
Douglas, Ian;
Olney, Jack;
D'Ancona, Grainne;
Smeeth, Liam;
Quint, Jennifer K;
(2019)
Cost saving of switching to equivalent inhalers and its effect on health outcomes.
THORAX, 74 (11).
pp. 1078-1086.
ISSN 0040-6376
DOI: https://doi.org/10.1136/thoraxjnl-2018-212957
Brown, Jeremy Philip;
Wing, Kevin;
Evans, Stephen J;
Bhaskaran, Krishnan;
Smeeth, Liam;
Douglas, Ian J;
(2019)
Use of real-world evidence in postmarketing medicines regulation in the European Union: a systematic assessment of European Medicines Agency referrals 2013-2017.
BMJ open, 9 (10).
e028133-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2018-028133
Gregson, J;
Qizilbash, N;
Iwagami, M;
Douglas, I;
Johnson, M;
Pearce, N;
Pocock, S;
(2019)
Blood pressure and risk of dementia and its subtypes: a historical cohort study with long-term follow-up in 2.6 million people.
European journal of neurology, 26 (12).
pp. 1479-1486.
ISSN 1351-5101
DOI: https://doi.org/10.1111/ene.14030
Lau, Wallis CY;
Douglas, Ian J;
Wong, Ian CK;
Smeeth, Liam;
Lip, Gregory YH;
Leung, Wai K;
Siu, Chung-Wah;
Cheung, Bernard MY;
Mok, Michael TC;
Chan, Esther W;
(2019)
Thromboembolic, bleeding, and mortality risks among patients with nonvalvular atrial fibrillation treated with dual antiplatelet therapy versus oral anticoagulants: A population-based study.
Heart Rhythm, 17 (1).
pp. 33-40.
ISSN 1547-5271
DOI: https://doi.org/10.1016/j.hrthm.2019.07.034
Nissen, FW;
(2019)
Asthma in electronic health records: validity and phenotyping.
PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04653375
Nissen, Francis;
Douglas, Ian J;
Müllerová, Hana;
Pearce, Neil;
Bloom, Chloe I;
Smeeth, Liam;
Quint, Jennifer K;
(2019)
Clinical profile of predefined asthma phenotypes in a large cohort of UK primary care patients (Clinical Practice Research Datalink).
Journal of asthma and allergy, 12.
pp. 7-19.
ISSN 1178-6965
DOI: https://doi.org/10.2147/JAA.S182013
Nissen, Francis;
Quint, Jennifer K;
Morales, Daniel R;
Douglas, Ian J;
(2019)
How to validate a diagnosis recorded in electronic health records.
European Respiratory Journal, 15 (1).
pp. 64-68.
ISSN 0903-1936
DOI: https://doi.org/10.1183/20734735.0344-2018
Root, Adrian;
Brown, Jeremy P;
Forbes, Harriet J;
Bhaskaran, Krishnan;
Hayes, Joseph;
Smeeth, Liam;
Douglas, Ian J;
(2019)
Association of Relative Age in the School Year With Diagnosis of Intellectual Disability, Attention-Deficit/Hyperactivity Disorder, and Depression.
JAMA Pediatrics, 173 (11).
pp. 1068-1075.
ISSN 2168-6203
DOI: https://doi.org/10.1001/jamapediatrics.2019.3194
Sinnott, Sarah-Jo;
Smeeth, Liam;
Williamson, Elizabeth;
Perel, Pablo;
Nitsch, Dorothea;
Tomlinson, Laurie A;
Douglas, Ian J;
(2019)
The comparative effectiveness of fourth-line drugs in resistant hypertension: An application in electronic health record data.
Pharmacoepidemiology and drug safety, 28 (9).
pp. 1267-1277.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.4808
2018
Bhaskaran, Krishnan;
Dos-Santos-Silva, Isabel;
Leon, David A;
Douglas, Ian J;
Smeeth, Liam;
(2018)
Association of BMI with overall and cause-specific mortality: a population-based cohort study of 3·6 million adults in the UK.
The lancet. Diabetes & endocrinology, 6 (12).
pp. 944-953.
ISSN 2213-8587
DOI: https://doi.org/10.1016/S2213-8587(18)30288-2
Crellin, Elizabeth;
Mansfield, Kathryn E;
Leyrat, Clémence;
Nitsch, Dorothea;
Douglas, Ian J;
Root, Adrian;
Williamson, Elizabeth;
Smeeth, Liam;
Tomlinson, Laurie A;
(2018)
Trimethoprim use for urinary tract infection and risk of adverse outcomes in older patients: cohort study.
BMJ (Clinical research ed), 360.
k341-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.k341
Iwagami, Masao;
Tomlinson, Laurie A;
Mansfield, Kathryn E;
Douglas, Ian J;
Smeeth, Liam;
Nitsch, Dorothea;
(2018)
Gastrointestinal bleeding risk of selective serotonin reuptake inhibitors by level of kidney function: A population-based cohort study.
British journal of clinical pharmacology, 84 (9).
pp. 2142-2151.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.13660
Koppe, Uwe;
Nitsch, Dorothea;
Mansfield, Kathryn E;
Mathur, Rohini;
Bhaskaran, Krishnan;
Batterham, Rachel L;
Smeeth, Liam;
Douglas, Ian J;
(2018)
Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink.
BMJ open, 8 (5).
e020371-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2017-020371
Mansfield, Kathryn E;
Douglas, Ian J;
Nitsch, Dorothea;
Thomas, Sara L;
Smeeth, Liam;
Tomlinson, Laurie A;
(2018)
Acute kidney injury and infections in patients taking antihypertensive drugs: a self-controlled case series analysis.
Clinical epidemiology, 10.
pp. 187-202.
ISSN 1179-1349
DOI: https://doi.org/10.2147/CLEP.S146757
Nissen, Francis;
Morales, Daniel R;
Mullerova, Hana;
Smeeth, Liam;
Douglas, Ian J;
Quint, Jennifer K;
(2018)
Concomitant diagnosis of asthma and COPD: a quantitative study in UK primary care.
The British journal of general practice, 68 (676).
e775-e782.
ISSN 0960-1643
DOI: https://doi.org/10.3399/bjgp18X699389
Rothnie, Kieran J;
Connell, Olivia;
Müllerová, Hana;
Smeeth, Liam;
Pearce, Neil;
Douglas, Ian;
Quint, Jennifer K;
(2018)
Myocardial Infarction and Ischemic Stroke after Exacerbations of Chronic Obstructive Pulmonary Disease.
Annals of the American Thoracic Society, 15 (8).
pp. 935-946.
ISSN 2329-6933
DOI: https://doi.org/10.1513/AnnalsATS.201710-815OC
Wilkinson, Samantha V;
Tomlinson, Laurie A;
Iwagami, Masao;
Stirnadel-Farrant, Heide A;
Smeeth, Liam;
Douglas, Ian;
(2018)
A systematic review comparing the evidence for kidney function outcomes between oral antidiabetic drugs for type 2 diabetes.
Wellcome open research, 3.
74-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14660.1
Wilkinson, Samantha;
Douglas, Ian J;
Williamson, Elizabeth;
Stirnadel-Farrant, Heide A;
Fogarty, Damian;
Pokrajac, Ana;
Smeeth, Liam;
Tomlinson, Laurie A;
(2018)
Factors associated with choice of intensification treatment for type 2 diabetes after metformin monotherapy: a cohort study in UK primary care.
CLINICAL EPIDEMIOLOGY, 10.
pp. 1639-1648.
ISSN 1179-1349
DOI: https://doi.org/10.2147/CLEP.S176142
Wilkinson, Samantha;
Douglas, Ian;
Stirnadel-Farrant, Heide;
Fogarty, Damian;
Pokrajac, Ana;
Smeeth, Liam;
Tomlinson, Laurie;
(2018)
Changing use of antidiabetic drugs in the UK: trends in prescribing 2000-2017.
BMJ open, 8 (7).
e022768-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2018-022768
Wing, Kevin;
Williamson, Elizabeth;
Carpenter, James R;
Wise, Lesley;
Schneeweiss, Sebastian;
Smeeth, Liam;
Quint, Jennifer K;
Douglas, Ian;
(2018)
Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results.
BMJ open, 8 (3).
e019475-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2017-019475
Zhou, Xiaofeng;
Douglas, Ian J;
Shen, Rongjun;
Bate, Andrew;
(2018)
Signal Detection for Recently Approved Products: Adapting and Evaluating Self-Controlled Case Series Method Using a US Claims and UK Electronic Medical Records Database.
Drug Saf, 41 (5).
pp. 523-536.
ISSN 1179-1942
DOI: https://doi.org/10.1007/s40264-017-0626-y
2017
Bloom, Chloe I;
Nissen, Francis;
Douglas, Ian J;
Smeeth, Liam;
Cullinan, Paul;
Quint, Jennifer K;
(2017)
Exacerbation risk and characterisation of the UK's asthma population from infants to old age.
Thorax, 73 (4).
pp. 313-320.
ISSN 0040-6376
DOI: https://doi.org/10.1136/thoraxjnl-2017-210650
Ghebremichael-Weldeselassie, Yonas;
Whitaker, Heather J;
Douglas, Ian J;
Smeeth, Liam;
Farrington, C Paddy;
(2017)
Self-controlled case series with multiple event types.
Computational statistics & data analysis, 113.
pp. 64-72.
ISSN 0167-9473
DOI: https://doi.org/10.1016/j.csda.2016.10.010
Full text not available from this repository.
Leyrat, C;
Seaman, SR;
White, IR;
Douglas, I;
Smeeth, L;
Kim, J;
Resche-Rigon, M;
Carpenter, JR;
Williamson, EJ;
(2017)
Propensity score analysis with partially observed covariates: How should multiple imputation be used?
Statistical methods in medical research.
p. 962280217713032.
ISSN 0962-2802
DOI: https://doi.org/10.1177/0962280217713032
Mathur, Rohini;
Bhaskaran, Krishnan;
Edwards, Emma;
Lee, Helen;
Chaturvedi, Nishi;
Smeeth, Liam;
Douglas, Ian;
(2017)
Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014.
BMJ open, 7 (2).
e014444-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2016-014444
Navaratnam, Vidya;
Root, Adrian A;
Douglas, Ian;
Smeeth, Liam;
Hubbard, Richard B;
Quint, Jennifer K;
(2017)
Cardiovascular Outcomes after a Respiratory Tract Infection among Adults with Non-Cystic Fibrosis Bronchiectasis: A General Population-based Study.
Annals of the American Thoracic Society, 15 (3).
pp. 315-321.
ISSN 2329-6933
DOI: https://doi.org/10.1513/AnnalsATS.201706-488OC
Nissen, Francis;
Morales, Daniel R;
Mullerova, Hana;
Smeeth, Liam;
Douglas, Ian J;
Quint, Jennifer K;
(2017)
Validation of asthma recording in the Clinical Practice Research Datalink (CPRD).
BMJ open, 7 (8).
e017474-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2017-017474
Nissen, Francis;
Quint, Jennifer K;
Wilkinson, Samantha;
Mullerova, Hana;
Smeeth, Liam;
Douglas, Ian J;
(2017)
Validation of asthma recording in electronic health records: a systematic review.
Clinical epidemiology, 9.
pp. 643-656.
ISSN 1179-1349
DOI: https://doi.org/10.2147/CLEP.S143718
Nissen, Francis;
Quint, Jennifer K;
Wilkinson, Samantha;
Mullerova, Hana;
Smeeth, Liam;
Douglas, Ian J;
(2017)
Validation of asthma recording in electronic health records: protocol for a systematic review.
BMJ open, 7 (5).
e014694-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2016-014694
Root, Adrian;
Douglas, Ian;
Evans, Stephen;
(2017)
Re: Biomedical Informatics Approaches to Identifying Drug-Drug Interactions: Application to Insulin Secretagogues.
Epidemiology (Cambridge, Mass), 29 (1).
e8-.
ISSN 1044-3983
DOI: https://doi.org/10.1097/EDE.0000000000000760
Full text not available from this repository.
Sinnott, Sarah-Jo;
Smeeth, Liam;
Williamson, Elizabeth;
Douglas, Ian J;
(2017)
Trends for prevalence and incidence of resistant hypertension: population based cohort study in the UK 1995-2015.
BMJ (Clinical research ed), 358.
j3984-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.j3984
Tomlinson, Laurie A;
Fogarty, Damian G;
Douglas, Ian;
Nitsch, Dorothea;
(2017)
Pharmacoepidemiology for nephrologists: do proton pump inhibitors cause chronic kidney disease?
Nephrology, dialysis, transplantation, 32 (suppl_).
ii40-ii46.
ISSN 0931-0509
DOI: https://doi.org/10.1093/ndt/gfw349
Wang, Shirley V;
Schneeweiss, Sebastian;
Berger, Marc L;
Brown, Jeffrey;
de Vries, Frank;
Douglas, Ian;
Gagne, Joshua J;
Gini, Rosa;
Klungel, Olaf;
Mullins, C Daniel;
+5 more...
Nguyen, Michael D;
Rassen, Jeremy A;
Smeeth, Liam;
Sturkenboom, Miriam;
joint ISPE-ISPOR Special Task Force on Real World Evidence in He;
(2017)
Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0.
Pharmacoepidemiology and drug safety, 26 (9).
pp. 1018-1032.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.4295
Wang, Shirley V;
Schneeweiss, Sebastian;
Berger, Marc L;
Brown, Jeffrey;
de Vries, Frank;
Douglas, Ian;
Gagne, Joshua J;
Gini, Rosa;
Klungel, Olaf;
Mullins, C Daniel;
+5 more...
Nguyen, Michael D;
Rassen, Jeremy A;
Smeeth, Liam;
Sturkenboom, Miriam;
joint ISPE‐ISPOR Special Task Force on Real World Evidence in He;
(2017)
Reporting to Improve Reproducibility and Facilitate Validity Assessment for Healthcare Database Studies V1.0.
Value in health, 20 (8).
pp. 1009-1022.
ISSN 1098-3015
DOI: https://doi.org/10.1016/j.jval.2017.08.3018
Full text not available from this repository.
Whitaker, Heather J;
Ghebremichael-Weldeselassie, Yonas;
Douglas, Ian J;
Smeeth, Liam;
Farrington, C Paddy;
(2017)
Investigating the assumptions of the self-controlled case series method.
Statistics in medicine, 37 (4).
pp. 643-658.
ISSN 0277-6715
DOI: https://doi.org/10.1002/sim.7536
Wing, Kevin;
Bhaskaran, Krishnan;
Pealing, Louise;
Root, Adrian;
Smeeth, Liam;
van Staa, Tjeerd P;
Klungel, Olaf H;
Reynolds, Robert F;
Douglas, Ian;
(2017)
Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.
The Journal of antimicrobial chemotherapy, 72 (9).
pp. 2636-2646.
ISSN 0305-7453
DOI: https://doi.org/10.1093/jac/dkx183
Yates, Tom A;
Tomlinson, Laurie A;
Bhaskaran, Krishnan;
Langan, Sinead;
Thomas, Sara;
Smeeth, Liam;
Douglas, Ian J;
(2017)
Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.
PLoS medicine, 14 (11).
e1002457-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1002457
2016
Beau-Lejdstrom, Raphaelle;
Douglas, Ian;
Evans, Stephen JW;
Smeeth, Liam;
(2016)
Latest trends in ADHD drug prescribing patterns in children in the UK: prevalence, incidence and persistence.
BMJ open, 6 (6).
e010508-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2015-010508
Chui, Celine SL;
Chan, Esther W;
Wong, Angel YS;
Root, Adrian;
Douglas, Ian J;
Wong, Ian CK;
(2016)
Association between oral fluoroquinolones and seizures: A self-controlled case series study.
Neurology, 86 (18).
pp. 1708-1715.
ISSN 0028-3878
DOI: https://doi.org/10.1212/WNL.0000000000002633
Douglas, Ian J;
Root, Adrian;
Krishnan, Bhaskaran;
(2016)
Oral Fluoroquinolone Use and Retinal Detachment.
JAMA ophthalmology, 134 (12).
1448-.
ISSN 2168-6165
DOI: https://doi.org/10.1001/jamaophthalmol.2016.3477
Matthews, Anthony;
Langan, Sinéad M;
Douglas, Ian J;
Smeeth, Liam;
Bhaskaran, Krishnan;
(2016)
Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink.
PLoS medicine, 13 (6).
e1002037-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1002037
Petersen, Irene;
Douglas, Ian;
Whitaker, Heather;
(2016)
Self controlled case series methods: an alternative to standard epidemiological study designs.
BMJ (Clinical research ed), 354.
i4515-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.i4515
Rawlins, Michael D;
Wexler, Nancy S;
Wexler, Alice R;
Tabrizi, Sarah J;
Douglas, Ian;
Evans, Stephen JW;
Smeeth, Liam;
(2016)
The Prevalence of Huntington's Disease.
Neuroepidemiology, 46 (2).
pp. 144-153.
ISSN 0251-5350
DOI: https://doi.org/10.1159/000443738
Rañopa, ME;
(2016)
Methodological issues in electronic healthcare database studies of drug cancer associations: identification of cancer, and drivers of
discrepant results.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.02572609
Root, AA;
Wong, AY;
Ghebremichael-Weldeselassie, Y;
Smeeth, L;
Bhaskaran, K;
Evans, SJ;
Brauer, R;
Wong, IC;
Navaratnam, V;
Douglas, I;
(2016)
Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.
British journal of clinical pharmacology, 82 (2).
pp. 512-21.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.12983
Sinnott, SJ;
Root, A;
Mathur, R;
Mansfield, K;
Tomlinson, L;
Douglas, I;
(2016)
OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS.
[Conference or Workshop Item]
https://doi.org/10.1097/01.hjh.0000499998.88068.07
Full text not available from this repository.
Sinnott, SJ;
Root, A;
Mathur, R;
Mansfield, K;
Tomlinson, L;
Douglas, I;
(2016)
OS 04-07 THE COMPARATIVE EFFECTIVENESS OF 4TH LINE ANTI-HYPERTENSIVE AGENTS IN PATIENTS WITH RESISTANT HYPERTENSION: A META-ANALYSIS.
[Conference or Workshop Item]
https://doi.org/10.1097/01.hjh.0000499998.88068.07
Full text not available from this repository.
Sinnott, SJ;
Tomlinson, LA;
Root, AA;
Mathur, R;
Mansfield, KE;
Smeeth, L;
Douglas, IJ;
(2016)
Comparative effectiveness of fourth-line anti-hypertensive agents in resistant hypertension: A systematic review and meta-analysis.
European journal of preventive cardiology.
ISSN 2047-4873
DOI: https://doi.org/10.1177/2047487316675194
Wexler, Nancy S;
Collett, Laura;
Wexler, Alice R;
Rawlins, Michael D;
Tabrizi, Sarah J;
Douglas, Ian;
Smeeth, Liam;
Evans, Stephen J;
(2016)
Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review.
BMJ open, 6 (2).
e009070-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2015-009070
Wing, Kevin;
(2016)
Improving the measurement and detection of serious adverse
drug reactions in databases of stored electronic health records.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.02545199
Wing, Kevin;
Bhaskaran, Krishnan;
Smeeth, Liam;
van Staa, Tjeerd P;
Klungel, Olaf H;
Reynolds, Robert F;
Douglas, Ian;
(2016)
Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.
BMJ open, 6 (9).
e012102-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2016-012102
Wong, Angel YS;
Root, Adrian;
Douglas, Ian J;
Chui, Celine SL;
Chan, Esther W;
Ghebremichael-Weldeselassie, Yonas;
Siu, Chung-Wah;
Smeeth, Liam;
Wong, Ian CK;
(2016)
Cardiovascular outcomes associated with use of clarithromycin: population based study.
BMJ (Clinical research ed), 352.
h6926-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.h6926
de Groot, MC;
Candore, G;
Uddin, MJ;
Souverein, PC;
Ali, MS;
Belitser, SV;
Huerta, C;
Groenwold, RH;
Alvarez, Y;
Slattery, J;
+9 more...
Korevaar, J;
Hoes, AW;
Roes, KC;
de Boer, A;
Douglas, IJ;
Schlienger, RG;
Reynolds, R;
Klungel, OH;
Gardarsdottir, H;
(2016)
Case-only designs for studying the association of antidepressants and hip or femur fracture.
Pharmacoepidemiology and drug safety, 25 Sup.
pp. 103-113.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3850
2015
Brauer, Ruth;
Bhaskaran, Krishnan;
Chaturvedi, Nishi;
Dexter, David T;
Smeeth, Liam;
Douglas, Ian;
(2015)
Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study.
PLoS medicine, 12 (7).
e1001854-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1001854
Brauer, Ruth;
Douglas, Ian;
Garcia Rodriguez, Luis Alberto;
Downey, Gerald;
Huerta, Consuelo;
de Abajo, Francisco;
Bate, Andrew;
Feudjo Tepie, Maurille;
de Groot, Mark CH;
Schlienger, Raymond;
+4 more...
Reynolds, Robert;
Smeeth, Liam;
Klungel, Olaf;
Ruigómez, Ana;
(2015)
Risk of acute liver injury associated with use of antibiotics. Comparative cohort and nested case-control studies using two primary care databases in Europe.
Pharmacoepidemiology and drug safety, 25 Sup (S1).
pp. 29-38.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3861
Full text not available from this repository.
Brauer, Ruth;
Ruigómez, Ana;
Downey, Gerry;
Bate, Andrew;
Garcia Rodriguez, Luis Alberto;
Huerta, Consuelo;
Gil, Miguel;
de Abajo, Francisco;
Requena, Gema;
Alvarez, Yolanda;
+13 more...
Slattery, Jim;
de Groot, Mark;
Souverein, Patrick;
Hesse, Ulrik;
Rottenkolber, Marietta;
Schmiedl, Sven;
de Vries, Frank;
Tepie, Maurille Feudjo;
Schlienger, Raymond;
Smeeth, Liam;
Douglas, Ian;
Reynolds, Robert;
Klungel, Olaf;
(2015)
Prevalence of antibiotic use: a comparison across various European health care data sources.
Pharmacoepidemiology and drug safety, 25 Sup (Suppl ).
pp. 11-20.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3831
Brauer, Ruth;
Ruigómez, Ana;
Klungel, Olaf;
Reynolds, Robert;
Feudjo Tepie, Maurille;
Smeeth, Liam;
Douglas, Ian;
(2015)
The risk of acute liver injury among users of antibiotic medications: a comparison of case-only studies.
Pharmacoepidemiology and drug safety, 25 Sup (Suppl ).
pp. 39-46.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3846
Douglas, Ian J;
Bhaskaran, Krishnan;
Batterham, Rachel L;
Smeeth, Liam;
(2015)
The effectiveness of pharmaceutical interventions for obesity: weight loss with orlistat and sibutramine in a United Kingdom population-based cohort.
British journal of clinical pharmacology, 79 (6).
pp. 1020-1027.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.12578
Douglas, Ian J;
Bhaskaran, Krishnan;
Batterham, Rachel L;
Smeeth, Liam;
(2015)
Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care.
PLoS medicine, 12 (12).
e1001925-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1001925
Hayes, JF;
Bhaskaran, K;
Batterham, R;
Smeeth, L;
Douglas, I;
(2015)
The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom.
Int J Obes (Lond), 39 (9).
pp. 1359-1364.
ISSN 1476-5497
DOI: https://doi.org/10.1038/ijo.2015.86
Minassian, C;
Thomas, S;
Smeeth, L;
Douglas, I;
Brauer, R;
Langan, S;
(2015)
Herpes zoster, acute cardiovascular events and the role of zoster vaccination.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/2312518
Full text not available from this repository.
Minassian, Caroline;
Thomas, Sara L;
Smeeth, Liam;
Douglas, Ian;
Brauer, Ruth;
Langan, Sinéad M;
(2015)
Acute Cardiovascular Events after Herpes Zoster: A Self-Controlled Case Series Analysis in Vaccinated and Unvaccinated Older Residents of the United States.
PLoS medicine, 12 (12).
e1001919-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1001919
Qizilbash, Nawab;
Gregson, John;
Johnson, Michelle E;
Pearce, Neil;
Douglas, Ian;
Wing, Kevin;
Evans, Stephen JW;
Pocock, Stuart J;
(2015)
BMI and risk of dementia in two million people over two decades: a retrospective cohort study.
The lancet Diabetes & endocrinology, 3 (6).
pp. 431-436.
ISSN 2213-8587
DOI: https://doi.org/10.1016/S2213-8587(15)00033-9
Full text not available from this repository.
Requena, Gema;
Logie, John;
Martin, Elisa;
Boudiaf, Nada;
González González, Rocío;
Huerta, Consuelo;
Alvarez, Arturo;
Webb, David;
Bate, Andrew;
García Rodríguez, Luis A;
+7 more...
Reynolds, Robert;
Schlienger, Raymond;
Gardarsdottir, Helga;
de Groot, Mark;
Klungel, Olaf H;
de Abajo, Fancisco;
Douglas, Ian J;
(2015)
Do case-only designs yield consistent results across design and different databases? A case study of hip fractures and benzodiazepines.
Pharmacoepidemiology and drug safety, 25 Sup (Suppl ).
pp. 79-87.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3822
Thomsen, RW;
Christensen, DH;
Kahlert, J;
Knudsen, ST;
Pedersen, L;
Norrelund, H;
Dekkers, OM;
Douglas, I;
Marchesini, G;
Smeeth, L;
+4 more...
Moller, N;
Beck-Nielsen, H;
Jorgensen, JO;
Sorensen, HT;
(2015)
Risk of pancreatic cancer associated with use of incretin-based therapy and other glucose-lowering agents: a nationwide case-control study in Denmark.
Diabetologia, 58.
S8-S9.
ISSN 0012-186X
https://researchonline.lshtm.ac.uk/id/eprint/2312529
Full text not available from this repository.
2014
Bhaskaran, Krishnan;
Douglas, Ian;
Forbes, Harriet;
dos-Santos-Silva, Isabel;
Leon, David A;
Smeeth, Liam;
(2014)
Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults.
Lancet, 384 (9945).
pp. 755-765.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(14)60892-8
Brauer, Ruth;
Smeeth, Liam;
Anaya-Izquierdo, Karim;
Timmis, Adam;
Denaxas, Spiros C;
Farrington, C Paddy;
Whitaker, Heather;
Hemingway, Harry;
Douglas, Ian;
(2014)
Antipsychotic drugs and risks of myocardial infarction: a self-controlled case series study.
European heart journal, 36 (16).
pp. 984-992.
ISSN 0195-668X
DOI: https://doi.org/10.1093/eurheartj/ehu263
Goh, Kah L;
Bhaskaran, Krishnan;
Minassian, Caroline;
Evans, Stephen JW;
Smeeth, Liam;
Douglas, Ian J;
(2014)
Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink.
British journal of clinical pharmacology, 79 (2).
pp. 337-350.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.12511
Macedo, Ana Filipa;
Douglas, Ian;
Smeeth, Liam;
Forbes, Harriet;
Ebrahim, Shah;
(2014)
Statins and the risk of type 2 diabetes mellitus: cohort study using the UK clinical practice pesearch datalink.
BMC cardiovascular disorders, 14 (1).
85-.
ISSN 1471-2261
DOI: https://doi.org/10.1186/1471-2261-14-85
Man, Kenneth KC;
Chan, Esther W;
Coghill, David;
Douglas, Ian;
Ip, Patrick;
Leung, Ling-Pong;
Tsui, Matthew SH;
Wong, Wilfred HS;
Wong, Ian CK;
(2014)
Methylphenidate and the risk of trauma.
Pediatrics, 135 (1).
pp. 40-48.
ISSN 0031-4005
DOI: https://doi.org/10.1542/peds.2014-1738
Full text not available from this repository.
Perel, Pablo;
Clayton, Tim;
Altman, Doug G;
Croft, Peter;
Douglas, Ian;
Hemingway, Harry;
Hingorani, Aroon;
Morley, Katherine I;
Riley, Richard;
Timmis, Adam;
+3 more...
Van der Windt, Danielle;
Roberts, Ian;
PROGRESS Partnership;
(2014)
Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.
PLoS medicine, 11 (6).
e1001664-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1001664
Rañopa, Michael;
Douglas, Ian;
van Staa, Tjeerd;
Smeeth, Liam;
Klungel, Olaf;
Reynolds, Robert;
Bhaskaran, Krishnan;
(2014)
The identification of incident cancers in UK primary care databases: a systematic review.
Pharmacoepidemiology and drug safety, 24 (1).
pp. 11-18.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.3729
Full text not available from this repository.
2013
Bhaskaran, Krishnan;
Forbes, Harriet J;
Douglas, Ian;
Leon, David A;
Smeeth, Liam;
(2013)
Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD).
BMJ open, 3 (9).
e003389-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2013-003389
Douglas, Ian J;
Langham, Julia;
Bhaskaran, Krishnan;
Brauer, Ruth;
Smeeth, Liam;
(2013)
Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink.
BMJ (Clinical research ed), 346 (apr12 ).
f1936-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.f1936
Douglas, Ian;
Evans, Stephen;
Rawlins, Michael D;
Smeeth, Liam;
Tabrizi, Sarah J;
Wexler, Nancy S;
(2013)
Juvenile Huntington's disease: a population-based study using the General Practice Research Database.
BMJ open, 3 (4).
e002085-e002085.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2012-002085
Evans, Stephen JW;
Douglas, Ian;
Rawlins, Michael D;
Wexler, Nancy S;
Tabrizi, Sarah J;
Smeeth, Liam;
(2013)
Prevalence of adult Huntington's disease in the UK based on diagnoses recorded in general practice records.
Journal of neurology, neurosurgery, and psychiatry, 84 (10).
pp. 1156-1160.
ISSN 0022-3050
DOI: https://doi.org/10.1136/jnnp-2012-304636
Skow, Aine;
Douglas, Ian;
Smeeth, Liam;
(2013)
The association between Parkinson's disease and anti-epilepsy drug carbamazepine: a case-control study using the UK General Practice Research Database.
British journal of clinical pharmacology, 76 (5).
pp. 816-822.
ISSN 0306-5251
DOI: https://doi.org/10.1111/bcp.12100
Wing, Kevin;
Douglas, Ian;
Bhaskaran, Krishnan;
Klungel, Olaf H;
Reynolds, Robert F;
Pirmohamed, Munir;
Smeeth, Liam;
van Staa, Tjeerd P;
(2013)
Development of predictive genetic tests for improving the safety of new medicines: the utilization of routinely collected electronic health records.
Drug discovery today, 19 (4).
pp. 361-366.
ISSN 1359-6446
DOI: https://doi.org/10.1016/j.drudis.2013.11.003
2012
Bhaskaran, Krishnan;
Douglas, Ian;
Evans, Stephen;
van Staa, Tjeerd;
Smeeth, Liam;
(2012)
Angiotensin receptor blockers and risk of cancer: cohort study among people receiving antihypertensive drugs in UK General Practice Research Database.
BMJ (Clinical research ed), 344 (apr24 ).
e2697-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.e2697
Brauer, R;
Smeeth, L;
Anaya-Izquierdo, K;
Farrington, CP;
Whitaker, H;
Douglas, I;
(2012)
A Comparison between the Standard Self Controlled Case Series Design and a Modification To Account for Events That Censor the Observation Period.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/612561
Full text not available from this repository.
Douglas, Ian J;
Evans, Stephen JW;
Hingorani, Aroon D;
Grosso, Anthony M;
Timmis, Adam;
Hemingway, Harry;
Smeeth, Liam;
(2012)
Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs.
BMJ (Clinical research ed), 345 (jul10 ).
e4388-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.e4388
2011
Beau, R;
Douglas, I;
Evans, S;
Clayton, T;
Smeeth, L;
(2011)
How Long Do Children Stay on Antiepileptic Treatments in the UK?
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/2
Full text not available from this repository.
Beau, R;
Douglas, I;
Stephen, E;
Clayton, T;
Smeeth, L;
(2011)
Comparison of Retention Rates of First Line Antiepileptic Drugs in Children in the UK.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/1
Full text not available from this repository.
Bhaskaran, K;
Douglas, I;
Evans, S;
van Staa, T;
Smeeth, L;
(2011)
The Risk of Cancer Associated with Angiotensin-II Receptor Blockers.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/5
Full text not available from this repository.
Brauer, R;
Douglas, I;
Smeeth, L;
(2011)
Using the Self Controlled Case Series Method To Assess the Risk of Myocardial Infarction in GPRD-Registered Users of Antipsychotic Agents.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/6
Full text not available from this repository.
Brauer, Ruth;
Douglas, Ian;
Smeeth, Liam;
(2011)
The association between antipsychotic agents and the risk of myocardial infarction: a systematic review.
British journal of clinical pharmacology, 72 (6).
pp. 871-878.
ISSN 0306-5251
DOI: https://doi.org/10.1111/j.1365-2125.2011.04043.x
Douglas, I;
Smeeth, L;
Hingorani, A;
Grosso, A;
Evans, S;
(2011)
A Cohort Study Using GPRD and MINAP Data To Investigate the Possible Drug Interaction between Clopidogrel and Cytochrome P450 2C19 Inhibitors.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/7
Full text not available from this repository.
Douglas, Ian;
Evans, Stephen;
Smeeth, Liam;
(2011)
Effect of statin treatment on short term mortality after pneumonia episode: cohort study.
BMJ, 342 (apr06 ).
d1642-.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.d1642
Douglas, Ian;
Smeeth, Liam;
Irvine, David;
(2011)
The use of antidepressants and the risk of haemorrhagic stroke: a nested case control study.
British journal of clinical pharmacology, 71 (1).
pp. 116-120.
ISSN 0306-5251
DOI: https://doi.org/10.1111/j.1365-2125.2010.03797.x
Full text not available from this repository.
Farrington, C Paddy;
Anaya-Izquierdo, Karim;
Whitaker, Heather J;
Hocine, Mounia N;
Douglas, Ian;
Smeeth, Liam;
(2011)
Self-Controlled Case Series Analysis With Event-Dependent Observation Periods.
Journal of the American Statistical Association, 106 (494).
pp. 417-426.
ISSN 0162-1459
DOI: https://doi.org/10.1198/jasa.2011.ap10108
Full text not available from this repository.
Grosso, Anthony;
Douglas, Ian;
MacAllister, Raymond;
Petersen, Irene;
Smeeth, Liam;
Hingorani, Aroon D;
(2011)
Use of the self-controlled case series method in drug safety assessment.
Expert opinion on drug safety, 10 (3).
pp. 337-340.
ISSN 1474-0338
DOI: https://doi.org/10.1517/14740338.2011.562187
Langham, Julia;
Douglas, Ian;
Brauer, Ruth;
Bhaskaran, Krishnan;
Smeeth, Liam;
(2011)
Abstracts of the 27th International Conference on Pharmacoepidemiology & Therapeutic Risk Management. Chicago, Illinois, USA. August 14-17, 2011.
Pharmacoepidemiology and drug safety, 20 Sup (S1).
S1-364.
ISSN 1053-8569
DOI: https://doi.org/10.1002/pds.2206
Full text not available from this repository.
McCandless, Lawrence C;
Douglas, Ian J;
Evans, Stephen J;
Smeeth, Liam;
(2011)
Cutting feedback in Bayesian regression adjustment for the propensity score.
The international journal of biostatistics, 6 (2).
Article-16.
ISSN 2194-573X
DOI: https://doi.org/10.2202/1557-4679.1205
2009
Douglas, Ian J;
Evans, Stephen J;
Pocock, Stuart;
Smeeth, Liam;
(2009)
The risk of fractures associated with thiazolidinediones: a self-controlled case-series study.
PLoS medicine, 6 (9).
e1000154-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1000154
Grosso, Anthony;
Douglas, Ian;
Hingorani, Aroon D;
MacAllister, Raymond;
Hubbard, Richard;
Smeeth, Liam;
(2009)
Inhaled tiotropium bromide and risk of stroke.
British journal of clinical pharmacology, 68 (5).
pp. 731-736.
ISSN 0306-5251
DOI: https://doi.org/10.1111/j.1365-2125.2009.03517.x
Full text not available from this repository.
Grosso, Anthony;
Douglas, Ian;
Hingorani, Aroon;
MacAllister, Raymond;
Smeeth, Liam;
(2009)
Oral bisphosphonates and risk of atrial fibrillation and flutter in women: a self-controlled case-series safety analysis.
PloS one, 4 (3).
e4720-.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0004720
Maguire, A;
Douglas, I;
Blak, BT;
(2009)
THE APPLICATION OF DISCRETE EVENT SIMULATION TO QUANTITATIVE RISK BENEFIT ANALYSIS.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/4488
Full text not available from this repository.
Smeeth, Liam;
Douglas, Ian;
Hall, Andrew J;
Hubbard, Richard;
Evans, Stephen;
(2009)
Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials.
British journal of clinical pharmacology, 67 (1).
pp. 99-109.
ISSN 0306-5251
DOI: https://doi.org/10.1111/j.1365-2125.2008.03308.x
Full text not available from this repository.
2008
Douglas, Ian J;
Smeeth, Liam;
(2008)
Exposure to antipsychotics and risk of stroke: self controlled case series study.
BMJ, 337 (aug28 ).
a1227-.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.a1227
Grosso, Anthony;
Douglas, Ian;
Hingorani, Aroon;
MacAllister, Raymond;
Smeeth, Liam;
(2008)
Post-marketing assessment of the safety of strontium ranelate; a novel case-only approach to the early detection of adverse drug reactions.
British journal of clinical pharmacology, 66 (5).
pp. 689-694.
ISSN 0306-5251
DOI: https://doi.org/10.1111/j.1365-2125.2008.03273.x
Full text not available from this repository.
Nitsch, Dorothea;
Douglas, Ian;
Smeeth, Liam;
Fletcher, Astrid;
(2008)
Age-related macular degeneration and complement activation-related diseases: a population-based case-control study.
Ophthalmology, 115 (11).
pp. 1904-1910.
ISSN 0161-6420
DOI: https://doi.org/10.1016/j.ophtha.2008.06.035
Full text not available from this repository.
2007
Douglas, IJ;
Smeeth, L;
Evans, SJ;
(2007)
A propensity score controlled cohort study to investigate the effects of statins.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/8492
Full text not available from this repository.
Douglas, Ian J;
Cook, Claire;
Chakravarthy, Usha;
Hubbard, Richard;
Fletcher, Astrid E;
Smeeth, Liam;
(2007)
A case-control study of drug risk factors for age-related macular degeneration.
Ophthalmology, 114 (6).
pp. 1164-1169.
ISSN 0161-6420
DOI: https://doi.org/10.1016/j.ophtha.2006.09.018
Full text not available from this repository.
Maguire, A;
Douglas, I;
Smeeth, L;
(2007)
Patterns of cholesterol levels in patients treated with lipid lowering drugs in UK primary care.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/8494
Full text not available from this repository.
Maguire, A;
Douglas, I;
Smeeth, L;
Thompson, M;
(2007)
Determinants of cholesterol and triglycerides recording in patients treated with lipid lowering therapy in UK primary care.
[Conference or Workshop Item]
https://doi.org/10.1002/pds
Full text not available from this repository.
Maguire, A;
Schwalm, MS;
Douglas, I;
Smeeth, L;
(2007)
Classification of hyperlipidemia from automated primary care data in the UK and France.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/8491
Full text not available from this repository.
2006
Smeeth, Liam;
Douglas, Ian;
Hubbard, Richard;
(2006)
Commentary: we still need observational studies of drugs--they just need to be better.
International journal of epidemiology, 35 (5).
pp. 1310-1311.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyl134
Full text not available from this repository.