Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.

Jabang, Sona; Erhart, Annette; Darboe, Saffiatou; Baldeh, Aru-Kumba; Delforge, Valerie; Watson, Gabriella; Foster-Nyarko, Ebenezer; Salaudeen, Rasheed; Lawal, Bolarinde; Mackenzie, Grant; +4 more... Botteaux, Anne; Antonio, Martin; Smeesters, Pierre R; On Behalf Of The Mrcg StrepA Study Group; (2021) Molecular Epidemiology of Group A Streptococcus Infections in The Gambia. Vaccines, 9 (2). p. 124. DOI: https://doi.org/10.3390/vaccines9020124

Abstract

Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.

Additional Information

Item Type	Article
Faculty and Department	MRC Gambia > GM-Disease Control and Elimination Theme Faculty of Infectious and Tropical Diseases > Dept of Disease Control Faculty of Infectious and Tropical Diseases > Department of Infection Biology MRC Gambia > GM-Vaccinology Theme
Research Centre	Centre for Epidemic Preparedness and Response
PubMed ID	33557233
Elements ID	156157