Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.
Jabang, Sona;
Erhart, Annette;
Darboe, Saffiatou;
Baldeh, Aru-Kumba;
Delforge, Valerie;
Watson, Gabriella;
Foster-Nyarko, Ebenezer;
Salaudeen, Rasheed;
Lawal, Bolarinde;
Mackenzie, Grant;
+4 more...Botteaux, Anne;
Antonio, Martin;
Smeesters, Pierre R;
On Behalf Of The Mrcg StrepA Study Group;
(2021)
Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.
Vaccines, 9 (2).
p. 124.
DOI: https://doi.org/10.3390/vaccines9020124
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Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.