Year Item Type Full Text

Article

Antiplasmodial activities of some Ghanaian plants traditionally used for fever/malaria treatment and of some alkaloids isolated from Pleiocarpa mutica; in vivo antimalarial activity of pleiocarpine. (2001) Addae-Kyereme, J; Croft, SL; Kendrick, H; Wright, CW

Case study for a vaccine against leishmaniasis. (2013) Alvar, Jorge; Croft, Simon L; Kaye, Paul; Khamesipour, Ali; Sundar, Shyam; Reed, Steven G

Tissue and host species-specific transcriptional changes in models of experimental visceral leishmaniasis. (2018) Ashwin, Helen; Seifert, Karin; Forrester, Sarah; Brown, Najmeeyah; MacDonald, Sandy; James, Sally; Lagos, Dimitris; Timmis, Jon; Mottram, Jeremy C; Croft, Simon L; Kaye, Paul M

In vitro antiprotozoal activity of extract and compounds from the stem bark of Combretum molle. (2001) Asres, K; Bucar, F; Knauder, E; Yardley, V; Kendrick, H; Croft, SL

Prediction of anti-plasmodial activity of Artemisia annua extracts: application of 1H NMR spectroscopy and chemometrics. (2004) Bailey, Nigel JC; Wang, Yulan; Sampson, Julia; Davis, Wendy; Whitcombe, Ian; Hylands, Peter J; Croft, Simon L; Holmes, Elaine

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. (2017) Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A

Prolylisoxazoles: potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. (2003) Bal, Gunther; Van der Veken, Pieter; Antonov, Dimitri; Lambeir, Anne-Marie; Grellier, Philippe; Croft, Simon L; Augustyns, Koen; Haemers, Achiel

Management of trypanosomiasis and leishmaniasis. (2012) Barrett, Michael P; Croft, Simon L

Emerging paradigms in anti-infective drug design. (2014) Barrett, Michael P; Croft, Simon L

Triclosan is minimally effective in rodent malaria models. (2011) Baschong, Werner; Wittlin, Sergio; Inglis, Kirstine A; Fairlamb, Alan H; Croft, Simon L; Kumar, TR Santha; Fidock, David A; Brun, Reto

In Vivo and In Vitro Activities and ADME-Tox Profile of a Quinolizidine-Modified 4-Aminoquinoline: A Potent Anti-P. falciparum and Anti-P. vivax Blood-Stage Antimalarial. (2017) Basilico, Nicoletta; Parapini, Silvia; Sparatore, Anna; Romeo, Sergio; Misiano, Paola; Vivas, Livia; Yardley, Vanessa; Croft, Simon L; Habluetzel, Annette; Lucantoni, Leonardo; Renia, Laurent; Russell, Bruce; Suwanarusk, Rossarin; Nosten, Francois; Dondio, Giulio; Bigogno, Chiara; Jabes, Daniela; Taramelli, Donatella

Miltefosine: issues to be addressed in the future. (2006) Berman, J; Bryceson, ADM; Croft, S; Engel, J; Gutteridge, W; Karbwang, J; Sindermann, H; Soto, J; Sundar, S; Urbina, JA

Metallocene-based antimalarials: an exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum. (2007) Blackie, Margaret AL; Beagley, Paul; Croft, Simon L; Kendrick, Howard; Moss, John R; Chibale, Kelly

Dose-dependent effect and pharmacokinetics of fexinidazole and its metabolites in a mouse model of human african trypanosomiasis. (2017) Burrell-Saward, H; Harris, AJ; de LaFlor, R; Sallam, H; Alavijeh, MS; Ward, TH; Croft, SL

A sensitive and reproducible in vivo imaging mouse model for evaluation of drugs against late-stage human African trypanosomiasis. (2014) Burrell-Saward, Hollie; Rodgers, Jean; Bradley, Barbara; Croft, Simon L; Ward, Theresa H

Screening of plant extracts for antiprotozoal and cytotoxic activities. (2003) Camacho, MDR; Phillipson, JD; Croft, SL; Solis, PN; Marshall, SJ; Ghazanfar, SA

Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. (2004) Cameron, Angus; Read, Jon; Tranter, Rebecca; Winter, Victoria J; Sessions, Richard B; Brady, R Leo; Vivas, Livia; Easton, Anna; Kendrick, Howard; Croft, Simon L; Barros, David; Lavandera, Jose Luis; Martin, José Julio; Risco, Felix; García-Ochoa, Silvestre; Gamo, Fracisco Javier; Sanz, Laura; Leon, Luisa; Ruiz, Jose R; Gabarró, Raquel; Mallo, Araceli; Gómez de las Heras, Federico

Understanding the transmission dynamics of Leishmania donovani to provide robust evidence for interventions to eliminate visceral leishmaniasis in Bihar, India. (2016) Cameron, Mary M; Acosta-Serrano, Alvaro; Bern, Caryn; Boelaert, Marleen; den Boer, Margriet; Burza, Sakib; Chapman, Lloyd AC; Chaskopoulou, Alexandra; Coleman, Michael; Courtenay, Orin; Croft, Simon; Das, Pradeep; Dilger, Erin; Foster, Geraldine; Garlapati, Rajesh; Haines, Lee; Harris, Angela; Hemingway, Janet; Hollingsworth, T Déirdre; Jervis, Sarah; Medley, Graham; Miles, Michael; Paine, Mark; Picado, Albert; Poché, Richard; Ready, Paul; Rogers, Matthew; Rowland, Mark; Sundar, Shyam; de Vlas, Sake J; Weetman, David

Route map for the discovery and pre-clinical development of new drugs and treatments for cutaneous leishmaniasis. (2019) Caridha, Diana; Vesely, Brian; van Bocxlaer, Katrien; Arana, Byron; Mowbray, Charles E; Rafati, Sima; Uliana, Silvia; Reguera, Rosa; Kreishman-Deitrick, Mara; Sciotti, Richard; Buffet, Pierre; Croft, Simon L

In vitro and in vivo antimalarial activity of peptidomimetic protein farnesyltransferase inhibitors with improved membrane permeability. (2004) Carrico, Dora; Ohkanda, Junko; Kendrick, Howard; Yokoyama, Kohei; Blaskovich, Michelle A; Bucher, Cynthia J; Buckner, Frederick S; Van Voorhis, Wesley C; Chakrabarti, Debopam; Croft, Simon L; Gelb, Michael H; Sebti, Saïd M; Hamilton, Andrew D

Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. (2003) Chauvière, Gérard; Bouteille, Bernard; Enanga, Bertin; de Albuquerque, Cristina; Croft, Simon L; Dumas, Michel; Périé, Jacques

Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. (2001) Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL

An efficient and novel technology for the extraction of parasite genomic DNA from whole blood or culture. (2019) Clark, David J; Moore, Catherine M; Flanagan, Marc; Bocxlaer, Katrien Van; Piperaki, Evangelia-Theophano; Yardley, Vanessa; Croft, Simon L; Tyson, John; Whitehouse, Sam P; O'Halloran, Jonathan; Krishna, Sanjeev; Staines, Henry M

Mapping the binding site for gossypol-like inhibitors of Plasmodium falciparum lactate dehydrogenase. (2005) Conners, Rebecca; Schambach, Felix; Read, Jon; Cameron, Angus; Sessions, Richard B; Vivas, Livia; Easton, Anna; Croft, Simon L; Brady, R Leo

Antikinetoplastid activity of 3-aryl-5-thiocyanatomethyl-1,2,4-oxadiazoles. (2004) Cottrell, Denise M; Capers, Jeffrey; Salem, Manar M; DeLuca-Fradley, Kate; Croft, Simon L; Werbovetz, Karl A

Kinetoplastida: new therapeutic strategies. (2008) Croft, SL

Monitoring drug resistance in leishmaniasis. (2001) Croft, SL

From natural products to drugs. (2001) Croft, SL

Essentials of antimicrobial pharmacology. Ed. P.H. Axelsen. Humana Press, 2001. Pp. 141. $24.50 pb. ISBN 0 896 03842 4. [Book Review]. (2002) Croft, SL

Leishmaniasis chemotherapy--challenges and opportunities. (2011) Croft, SL; Olliaro, P

Recent advances in research and control of malaria, leishmaniasis, trypanosomiasis and schistosomiasis. (2003) Croft, SL; Vivas, L; Brooker, S

Antimalarial Chemotherapy: Mechanisms of Action, Resistance and New Directions in Drug Discovery. (2001) Croft, Simon

PKDL--a drug related phenomenon? (2008) Croft, Simon L

Neglected tropical diseases in the genomics era: re-evaluating the impact of new drugs and mass drug administration. (2016) Croft, Simon L

Leishmania and other intracellular pathogens: selectivity, drug distribution and PK-PD. (2016) Croft, Simon L

Antileishmanial and antitrypanosomal drug identification. (2017) Croft, Simon L; Chatelain, Eric; Barrett, Michael P picture_as_pdf

Leishmaniasis--current chemotherapy and recent advances in the search for novel drugs. (2003) Croft, Simon L; Coombs, Graham H

Review of pyronaridine anti-malarial properties and product characteristics. (2012) Croft, Simon L; Duparc, Stephan; Arbe-Barnes, Sarah J; Craft, J Carl; Shin, Chang-Sik; Fleckenstein, Lawrence; Borghini-Fuhrer, Isabelle; Rim, Han-Jong

Antiprotozoal activities of phospholipid analogues. (2003) Croft, Simon L; Seifert, Karin; Duchêne, Michael

Current scenario of drug development for leishmaniasis. (2006) Croft, Simon L; Seifert, Karin; Yardley, Vanessa

Drug resistance in leishmaniasis. (2006) Croft, Simon L; Sundar, Shyam; Fairlamb, Alan H

The Nobel Prize in Medicine 2015: Two drugs that changed global health. (2015) Croft, Simon L; Ward, Steven

Chemotherapy of leishmaniasis. (2002) Croft, Simon L; Yardley, Vanessa

Drug sensitivity of Leishmania species: some unresolved problems. (2002) Croft, Simon L; Yardley, Vanessa; Kendrick, Howard

Modular multiantigen T cell epitope-enriched DNA vaccine against human leishmaniasis. (2014) Das, Shantanabha; Freier, Anja; Boussoffara, Thouraya; Das, Sushmita; Oswald, Detlef; Losch, Florian O; Selka, Melanie; Sacerdoti-Sierra, Nina; Schönian, Gabriele; Wiesmüller, Karl-Heinz; Seifert, Karin; Schroff, Matthias; Juhls, Christiane; Jaffe, Charles L; Roy, Syamal; Das, Pradeep; Louzir, Hechmi; Croft, Simon L; Modabber, Farrokh; Walden, Peter

QSAR study on the contribution of log P and E(s) to the in vitro antiprotozoal activity of glutathione derivatives. (2001) Daunes, S; D'Silva, C; Kendrick, H; Yardley, V; Croft, SL

Antiprotozoal glutathione derivatives with flagellar membrane binding activity against T. brucei rhodesiense. (2016) Daunes, S; Yardley, V; Croft, SL; D'Silva, C

Leishmaniasis: new approaches to disease control. (2003) Davies, Clive R; Kaye, Paul; Croft, Simon L; Sundar, Shyam

Antimalarial and cytotoxic activities of chiral triamines. (2013) Dellai, Afef; Appel, Jon; Bouraoui, Abderrahman; Croft, Simon; Nefzi, Adel

Costs and outcomes of active and passive case detection for visceral leishmaniasis (Kala-Azar) to inform elimination strategies in Bihar, India. (2021) Dial, Natalie J; Medley, Graham F; Croft, Simon L; Mahapatra, Tanmay; Priyamvada, Khushbu; Sinha, Bikas; Palmer, Lucy; Terris-Prestholt, Fern

Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas. (2010) Dujardin, Jean-Claude; González-Pacanowska, Dolores; Croft, Simon L; Olesen, Ole F; Späth, Gerald F

Activities of hexadecylphosphocholine (miltefosine), AmBisome, and sodium stibogluconate (Pentostam) against Leishmania donovani in immunodeficient scid mice. (2001) Escobar, P; Yardley, V; Croft, SL

Sensitivities of Leishmania species to hexadecylphosphocholine (miltefosine), ET-18-OCH(3) (edelfosine) and amphotericin B. (2002) Escobar, Patricia; Matu, Sangeeta; Marques, Cláudia; Croft, Simon L

Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents. (2008) Fattorusso, Caterina; Campiani, Giuseppe; Kukreja, Gagan; Persico, Marco; Butini, Stefania; Romano, Maria Pia; Altarelli, Maria; Ros, Sindu; Brindisi, Margherita; Savini, Luisa; Novellino, Ettore; Nacci, Vito; Fattorusso, Ernesto; Parapini, Silvia; Basilico, Nicoletta; Taramelli, Donatella; Yardley, Vanessa; Croft, Simon; Borriello, Marianna; Gemma, Sandra

Antimalarial drug discovery: efficacy models for compound screening. (2004) Fidock, David A; Rosenthal, Philip J; Croft, Simon L; Brun, Reto; Nwaka, Solomon

Tissue-specific transcriptomic changes associated with AmBisome® treatment of BALB/c mice with experimental visceral leishmaniasis. (2019) Forrester, Sarah; Siefert, Karin; Ashwin, Helen; Brown, Najmeeyah; Zelmar, Andrea; James, Sally; Lagos, Dimitris; Timmis, Jon; Chatterjee, Mitali; Mottram, Jeremy C; Croft, Simon L; Kaye, Paul M

Biomedicine and biotechnology: public health impact. (2014) Ganguly, Nirmal K; Croft, Simon; Singh, Lalji; Sinha, Subrata; Balganesh, Tanjore

In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis. (2006) Garnier, Tracy; Brown, Marc B; Lawrence, M Jayne; Croft, Simon L

Topical treatment for cutaneous leishmaniasis. (2002) Garnier, Tracy; Croft, Simon L

In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs. (2007) Garnier, Tracy; Mäntylä, Antti; Järvinen, Tomi; Lawrence, Jayne; Brown, Marc; Croft, Simon

Topical buparvaquone formulations for the treatment of cutaneous leishmaniasis. (2007) Garnier, Tracy; Mäntylä, Antti; Järvinen, Tomi; Lawrence, M Jayne; Brown, Marc B; Croft, Simon L

Combining 4-aminoquinoline- and clotrimazole-based pharmacophores toward innovative and potent hybrid antimalarials. (2009) Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Joshi, Bhupendra P; Kukreja, Gagan; Coccone, Salvatore Sanna; Bernetti, Matteo; Persico, Marco; Nacci, Vito; Fiorini, Isabella; Novellino, Ettore; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Yardley, Vanessa; Croft, Simon; Keller-Maerki, Sonja; Rottmann, Matthias; Brun, Reto; Coletta, Massimiliano; Marini, Stefano; Guiso, Giovanna; Caccia, Silvio; Fattorusso, Caterina

Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies. (2008) Gemma, Sandra; Campiani, Giuseppe; Butini, Stefania; Kukreja, Gagan; Coccone, Salvatore Sanna; Joshi, Bhupendra P; Persico, Marco; Nacci, Vito; Fiorini, Isabella; Novellino, Ettore; Fattorusso, Ernesto; Taglialatela-Scafati, Orazio; Savini, Luisa; Taramelli, Donatella; Basilico, Nicoletta; Parapini, Silvia; Morace, Giulia; Yardley, Vanessa; Croft, Simon; Coletta, Massimiliano; Marini, Stefano; Fattorusso, Caterina

Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. (2004) Ghosh, Subhash; Chan, Julian MW; Lea, Christopher R; Meints, Gary A; Lewis, Jared C; Tovian, Zev S; Flessner, Ryan M; Loftus, Timothy C; Bruchhaus, Iris; Kendrick, Howard; Croft, Simon L; Kemp, Robert G; Kobayashi, Seiki; Nozaki, Tomoyoshi; Oldfield, Eric

Synthesis and characterization of copper(II) complexes of pyridine-2-carboxamidrazones as potent antimalarial agents. (2003) Gokhale, Nikhil H; Padhye, Subhash B; Billington, David C; Rathbone, Daniel L; Croft, Simon L; Kendrick, Howard D; Anson, Christopher E; Powell, Annie K

Transition metal complexes of buparvaquone as potent new antimalarial agents. 1. Synthesis, X-ray crystal-structures, electrochemistry and antimalarial activity against Plasmodium falciparum. (2003) Gokhale, Nikhil H; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Davies, Wendy; Anson, Christopher E; Powell, Annie K

Metalloantimalarials: synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. (2006) Gokhale, Nikhil H; Shirisha, K; Padhye, Subhash B; Croft, Simon L; Kendrick, Howard D; Mckee, Vickie

Inhibitors of Leishmania mexicana CRK3 cyclin-dependent kinase: chemical library screen and antileishmanial activity. (2004) Grant, Karen M; Dunion, Morag H; Yardley, Vanessa; Skaltsounis, Alexios-Leandros; Marko, Doris; Eisenbrand, Gerhard; Croft, Simon L; Meijer, Laurent; Mottram, Jeremy C

New azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action. (2006) Gros, Ludovic; Castillo-Acosta, Victor Manuel; Jiménez Jiménez, Carmen; Sealey-Cardona, Marco; Vargas, Sofia; Manuel Estévez, Antonio; Yardley, Vanessa; Rattray, Lauren; Croft, Simon L; Ruiz-Perez, Luis M; Urbina, Julio A; Gilbert, Ian H; González-Pacanowska, Dolores

Evaluation of azasterols as anti-parasitics. (2006) Gros, Ludovic; Lorente, Silvia Orenes; Jimenez, Carmen Jimenez; Yardley, Vanessa; Rattray, Lauren; Wharton, Hayley; Little, Susan; Croft, Simon L; Ruiz-Perez, Luis M; Gonzalez-Pacanowska, Dolores; Gilbert, Ian H

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda. (2002) Guerin, Philippe J; Olliaro, Piero; Sundar, Shyam; Boelaert, Marleen; Croft, Simon L; Desjeux, Philippe; Wasunna, Monique K; Bryceson, Anthony DM

A new series of amodiaquine analogues modified in the basic side chain with in vitro antileishmanial and antiplasmodial activity. (2009) Guglielmo, Stefano; Bertinaria, Massimo; Rolando, Barbara; Crosetti, Marco; Fruttero, Roberta; Yardley, Vanessa; Croft, Simon L; Gasco, Alberto

Single-use acupuncture needles: scanning electron-microscopy of needle-tips. (2002) Hayhoe, Simon; McCrossan, Maria; Smith, Aden; Ellis, David; Croft, Simon; Mei, Man Fong

Artemisone--a highly active antimalarial drug of the artemisinin class. (2006) Haynes, Richard K; Fugmann, Burkhard; Stetter, Jörg; Rieckmann, Karl; Heilmann, Hans-Dietrich; Chan, Ho-Wai; Cheung, Man-Ki; Lam, Wai-Lun; Wong, Ho-Ning; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Peters, Wallace; Robinson, Brian L; Edstein, Michael D; Kotecka, Barbara; Kyle, Dennis E; Beckermann, Bernhard; Gerisch, Michael; Radtke, Martin; Schmuck, Gabriele; Steinke, Wolfram; Wollborn, Ute; Schmeer, Karl; Römer, Axel

Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity. (2004) Haynes, Richard K; Ho, Wing-Yan; Chan, Ho-Wai; Fugmann, Burkhard; Stetter, Jörg; Croft, Simon L; Vivas, Livia; Peters, Wallace; Robinson, Brian L

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. (2007) Haynes, Richard K; Wong, Ho-Ning; Lee, Kin-Wo; Lung, Chung-Man; Shek, Lai Yung; Williams, Ian D; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Wong, Vincent KW; Ko, Ben CB

Evaluating drug resistance in visceral leishmaniasis: the challenges. (2016) Hendrickx, S; Guerin, PJ; Caljon, G; Croft, SL; Maes, L

Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates. (2006) Hudock, Michael P; Sanz-Rodríguez, CE; Song, Yongcheng; Chan, Julian MW; Zhang, Yonghui; Odeh, Sarah; Kosztowski, Thomas; Leon-Rossell, Annette; Concepción, JL; Yardley, Vanessa; Croft, Simon L; Urbina, Julio A; Oldfield, Eric

The distribution of nifurtimox across the healthy and trypanosome-infected murine blood-brain and blood-cerebrospinal fluid barriers. (2011) Jeganathan, Sinthujah; Sanderson, Lisa; Dogruel, Murat; Rodgers, Jean; Croft, Simon; Thomas, Sarah A

Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives. (2004) Jung, Mankil; Lee, Kyunghoon; Jung, Hochul; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L

Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid. (2002) Jung, Mankil; Lee, Kyunghoon; Kendrick, Howard; Robinson, Brian L; Croft, Simon L

Chemical and bioassay techniques to authenticate quality of the anti-leishmanial drug miltefosine. (2015) Kaur, Harparkash; Seifert, Karin; Hawkes, Geoffrey E; Coumbarides, Gregory S; Alvar, Jorge; Croft, Simon L

Leishmaniasis immunopathology-impact on design and use of vaccines, diagnostics and drugs. (2020) Kaye, Paul M; Cruz, Israel; Picado, Albert; Van Bocxlaer, Katrien; Croft, Simon L

Natural products as antiparasitic drugs. (2003) Kayser, O; Kiderlen, AF; Croft, SL

Formulation and biopharmaceutical issues in the development of drug delivery systems for antiparasitic drugs. (2003) Kayser, O; Olbrich, C; Croft, SL; Kiderlen, AF

Formulation of amphotericin B as nanosuspension for oral administration. (2003) Kayser, O; Olbrich, C; Yardley, V; Kiderlen, AF; Croft, SL

Antileishmanial activity of two gamma-pyrones from Podolepsis hieracioides (Asteraceae). (2003) Kayser, Oliver; Kiderlen, Albrecht F; Croft, Simon L

Metabolic, immune, and gut microbial signals mount a systems response to Leishmania major infection. (2014) Lamour, Sabrina D; Veselkov, Kirill A; Posma, Joram M; Giraud, Emilie; Rogers, Matthew E; Croft, Simon; Marchesi, Julian R; Holmes, Elaine; Seifert, Karin; Saric, Jasmina

Toxicity and antileishmanial activity of a new stable lipid suspension of amphotericin B. (2003) Larabi, Malika; Yardley, Vanessa; Loiseau, Philippe M; Appel, Martine; Legrand, Philippe; Gulik, Annette; Bories, Christian; Croft, Simon L; Barratt, Gillian

Epidemiological dynamics of antimonial resistance in Leishmania donovani: genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal. (2006) Laurent, Thierry; Rijal, Suman; Yardley, Vanessa; Croft, Simon; De Doncker, Simonne; Decuypere, Saskia; Khanal, Basudha; Singh, Rupa; Schönian, Gabriele; Kuhls, Katrin; Chappuis, François; Dujardin, Jean-Claude

Corrigendum to “Structure–activity relationships of antileishmanial and antimalarial chalcones” (Bioorg. Chem. 2003, 11, 2729–2738]. (2004) Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin

Structure-activity relationships of antileishmanial and antimalarial chalcones. (2003) Liu, Mei; Wilairat, Prapon; Croft, Simon L; Tan, Agnes Lay-Choo; Go, Mei-Lin

Chitosan Contribution to Therapeutic and Vaccinal Approaches for the Control of Leishmaniasis. (2020) Loiseau, Philippe M; Pomel, Sébastien; Croft, Simon L

Novel azasterols as potential agents for treatment of leishmaniasis and trypanosomiasis. (2004) Lorente, Silvia Orenes; Rodrigues, Juliany CF; Jiménez Jiménez, Carmen; Joyce-Menekse, Miranda; Rodrigues, Carlos; Croft, Simon L; Yardley, Vanessa; de Luca-Fradley, Kate; Ruiz-Pérez, Luis M; Urbina, Julio; de Souza, Wanderley; González Pacanowska, Dolores; Gilbert, Ian H

In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. (2009) Luna, Katherine Paola; Hernández, Indira Paola; Rueda, César Mauricio; Zorro, María Magdalena; Croft, Simon L; Escobar, Patricia

In vivo monitoring of intracellular ATP levels in Leishmania donovani promastigotes as a rapid method to screen drugs targeting bioenergetic metabolism. (2001) Luque-Ortega, JR; Rivero-Lezcano, OM; Croft, SL; Rivas, L

Azasterols as inhibitors of sterol 24-methyltransferase in Leishmania species and Trypanosoma cruzi. (2003) Magaraci, Filippo; Jimenez, Carmen Jimenez; Rodrigues, Carlos; Rodrigues, Juliany CF; Braga, Marina Vianna; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; de Souza, Wanderley; Ruiz-Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. (2001) Martin, MB; Grimley, JS; Lewis, JC; Heath, HT; Bailey, BN; Kendrick, H; Yardley, V; Caldera, A; Lira, R; Urbina, JA; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E

Activity of bisphosphonates against Trypanosoma brucei rhodesiense. (2002) Martin, Michael B; Sanders, John M; Kendrick, Howard; de Luca-Fradley, Kate; Lewis, Jared C; Grimley, Joshua S; Van Brussel, Erin M; Olsen, Jeffrey R; Meints, Gary A; Burzynska, Agnieszka; Kafarski, Pawel; Croft, Simon L; Oldfield, Eric

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase. (2013) McLatchie, Alex P; Burrell-Saward, Hollie; Myburgh, Elmarie; Lewis, Michael D; Ward, Theresa H; Mottram, Jeremy C; Croft, Simon L; Kelly, John M; Taylor, Martin C

Recent advances in development of amphotericin B formulations for the treatment of visceral leishmaniasis. (2012) Mohamed-Ahmed, Abeer HA; Brocchini, Stephen; Croft, Simon L

Noncovalent complexation of amphotericin-B with Poly(α-glutamic acid). (2013) Mohamed-Ahmed, Abeer HA; Les, Karolina A; Seifert, Karin; Croft, Simon L; Brocchini, Stephen

Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex. (2013) Mohamed-Ahmed, Abeer HA; Seifert, Karin; Yardley, Vanessa; Burrell-Saward, Hollie; Brocchini, Stephen; Croft, Simon L

Isolation and in vitro antiplasmodial activities of alkaloids from Teclea trichocarpa: in vivo antimalarial activity and X-ray crystal structure of normelicopicine. (2002) Muriithi, Mary W; Abraham, W-R; Addae-Kyereme, Jonathan; Scowen, Ian; Croft, Simon L; Gitu, Peter M; Kendrick, Howard; Njagi, ENM; Wright, Colin W

The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. (2001) Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; Upton, RJ; Croft, SL; Clegg, W; Elsegood, MR

Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone. (2004) Mäntylä, Antti; Garnier, Tracy; Rautio, Jarkko; Nevalainen, Tapio; Vepsälainen, Jouko; Koskinen, Ari; Croft, Simon L; Järvinen, Tomi

Synthesis and antileishmanial activity of novel buparvaquone oxime derivatives. (2004) Mäntylä, Antti; Rautio, Jarkko; Nevalainen, Tapio; Vepsälainen, Jouko; Juvonen, Risto; Kendrick, Howard; Garnier, Tracy; Croft, Simon L; Järvinen, Tomi

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs. (2001) Nan, A; Nanayakkara, NP; Walker, LA; Yardley, V; Croft, SL; Ghandehari, H

Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis. (2004) Nan, Anjan; Croft, Simon L; Yardley, Vanessa; Ghandehari, Hamidreza

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichlorophenoxy]quinoline succinate. (2008) Nanayakkara, NP Dhammika; Ager, Arba L; Bartlett, Marilyn S; Yardley, Vanessa; Croft, Simon L; Khan, Ikhlas A; McChesney, James D; Walker, Larry A

Antiparasitic activities and toxicities of individual enantiomers of the 8-aminoquinoline 8-[(4-amino-1-methylbutyl)amino]-6-methoxy-4-methyl-5-[3,4-dichloropheno xy]quinoline succinate. (2008) Nanayakkara, NP; Ager, AL; Bartlett, MS; Yardley, V; Croft, SL; Khan, IA; McChesney, JD; Walker, LA

Novel 2D and 3D Assays to Determine the Activity of Anti-Leishmanial Drugs. (2020) O'Keeffe, Alec; Hale, Christine; Cotton, James A; Yardley, Vanessa; Gupta, Kapish; Ananthanarayanan, Abhishek; Murdan, Sudaxshina; Croft, Simon L

Development of an in vitro media perfusion model of Leishmania major macrophage infection. (2019) O'Keeffe, Alec; Hyndman, Lauren; McGinty, Sean; Riezk, Alaa; Murdan, Sudaxshina; Croft, Simon L

Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. (2001) Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; Hamilton, AD

Design and synthesis of peptidomimetic protein farnesyltransferase inhibitors as anti-Trypanosoma brucei agents. (2004) Ohkanda, Junko; Buckner, Frederick S; Lockman, Jeffrey W; Yokoyama, Kohei; Carrico, Dora; Eastman, Richard; de Luca-Fradley, Kate; Davies, Wendy; Croft, Simon L; Van Voorhis, Wesley C; Gelb, Michael H; Sebti, Saïd M; Hamilton, Andrew D

Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action. (2005) Onyeibor, Onyeka; Croft, Simon L; Dodson, Hilary I; Feiz-Haddad, Mohammad; Kendrick, Howard; Millington, Nicola J; Parapini, Silvia; Phillips, Roger M; Seville, Scott; Shnyder, Steven D; Taramelli, Donatella; Wright, Colin W

Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa. (2005) Orenes Lorente, Silvia; Gómez, Rosario; Jiménez, Carmen; Cammerer, Simon; Yardley, Vanessa; de Luca-Fradley, Kate; Croft, Simon L; Ruiz Perez, Luis M; Urbina, Julio; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Antitrypanosomal, antileishmanial, and antimalarial activities of quaternary arylalkylammonium 2-amino-4-chlorophenyl phenyl sulfides, a new class of trypanothione reductase inhibitor, and of N-acyl derivatives of 2-amino-4-chlorophenyl phenyl sulfide. (2005) Parveen, Seheli; Khan, Mohammed OF; Austin, Susan E; Croft, Simon L; Yardley, Vanessa; Rock, Peter; Douglas, Kenneth T

2,4-Diaminopyrimidines as inhibitors of Leishmanial and Trypanosomal dihydrofolate reductase. (2003) Pez, Didier; Leal, Isabel; Zuccotto, Fabio; Boussard, Cyrille; Brun, Reto; Croft, Simon L; Yardley, Vanessa; Ruiz Perez, Luis M; Gonzalez Pacanowska, Dolores; Gilbert, Ian H

Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. (2012) Peña, Stella; Scarone, Laura; Manta, Eduardo; Stewart, Lindsay; Yardley, Vanessa; Croft, Simon; Serra, Gloria

Mechanisms of experimental resistance of Leishmania to miltefosine: Implications for clinical use. (2006) Pérez-Victoria, F Javier; Sánchez-Cañete, María P; Seifert, Karin; Croft, Simon L; Sundar, Shyam; Castanys, Santiago; Gamarro, Francisco

Cissampeloflavone, a chalcone-flavone dimer from Cissampelos pareira. (2003) Ramírez, Irama; Carabot, Alfredo; Meléndez, Pablo; Carmona, Juan; Jimenez, Manuel; Patel, Asmita V; Crabb, Trevor A; Blunden, Gerald; Cary, Peter D; Croft, Simon L; Costa, Manuel

Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. (2001) Ren, H; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G

Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. (2003) Ren, Hongyu; Grady, Shannon; Banghart, Matthew; Moulthrop, Jason S; Kendrick, Howard; Yardley, Vanessa; Croft, Simon L; Moyna, Guillermo

Preclinical safety and tolerability of a repeatedly administered human leishmaniasis DNA vaccine. (2015) Riede, O; Seifert, K; Oswald, D; Endmann, A; Hock, C; Winkler, A; Salguero, FJ; Schroff, M; Croft, SL; Juhls, C

Activity of Chitosan and Its Derivatives against Leishmania major and Leishmania mexicana In Vitro. (2019) Riezk, Alaa; Raynes, John G; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Activity of Amphotericin B-Loaded Chitosan Nanoparticles against Experimental Cutaneous Leishmaniasis. (2020) Riezk, Alaa; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Antimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome? (2007) Rijal, Suman; Yardley, Vanessa; Chappuis, François; Decuypere, Saskia; Khanal, Basudha; Singh, Rupa; Boelaert, Marleen; De Doncker, Simonne; Croft, Simon; Dujardin, Jean-Claude

Mast cells at the host-pathogen interface: host-protection versus immune evasion in leishmaniasis. (2004) Saha, B; Tonkal, AMDJ; Croft, S; Roy, S

2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity. (2001) Salmon-Chemin, L; Buisine, E; Yardley, V; Kohler, S; Debreu, MA; Landry, V; Sergheraert, C; Croft, SL; Krauth-Siegel, RL; Davioud-Charvet, E

Activity of anti-cancer protein kinase inhibitors against Leishmania spp. (2014) Sanderson, Lisa; Yardley, Vanessa; Croft, Simon L

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug. (2021) Sanderson, Lisa; da Silva, Marcelo; Sekhar, Gayathri N; Brown, Rachel C; Burrell-Saward, Hollie; Fidanboylu, Mehmet; Liu, Bo; Dailey, Lea Ann; Dreiss, Cécile A; Lorenz, Chris; Christie, Mark; Persaud, Shanta J; Yardley, Vanessa; Croft, Simon L; Valero, Margarita; Thomas, Sarah A

Antiparasitic activities of acridone alkaloids from Swinglea glutinosa (Bl.) Merr. (2009) Santos, Djalma AP dos; Vieira, Paulo C; Silva, M Fátima das GF da; Fernandes, João B; Rattray, Lauren; Croft, Simon L

In vitro and in vivo interactions between miltefosine and other antileishmanial drugs. (2006) Seifert, Karin; Croft, Simon L

In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. (2010) Seifert, Karin; Escobar, Patricia; Croft, Simon L

Sequential chemoimmunotherapy of experimental visceral leishmaniasis using a single low dose of liposomal amphotericin B and a novel DNA vaccine candidate. (2015) Seifert, Karin; Juhls, Christiane; Salguero, Francisco J; Croft, Simon L

Antileishmanial structure-activity relationships of synthetic phospholipids: in vitro and in vivo activities of selected derivatives. (2007) Seifert, Karin; Lemke, Andreas; Croft, Simon L; Kayser, Oliver

Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine). (2003) Seifert, Karin; Matu, Sangeeta; Javier Pérez-Victoria, F; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L

In vitro interactions between sitamaquine and amphotericin B, sodium stibogluconate, miltefosine, paromomycin and pentamidine against Leishmania donovani. (2011) Seifert, Karin; Munday, Jane; Syeda, Tahmina; Croft, Simon L

Inactivation of the miltefosine transporter, LdMT, causes miltefosine resistance that is conferred to the amastigote stage of Leishmania donovani and persists in vivo. (2007) Seifert, Karin; Pérez-Victoria, F Javier; Stettler, Marianne; Sánchez-Cañete, María P; Castanys, Santiago; Gamarro, Francisco; Croft, Simon L

Innovations for the elimination and control of visceral leishmaniasis. (2019) Selvapandiyan, Angamuthu; Croft, Simon L; Rijal, Suman; Nakhasi, Hira L; Ganguly, Nirmal K

Miltefosine (Impavido): the first oral treatment against leishmaniasis. (2004) Sindermann, H; Croft, SL; Engel, KR; Bommer, W; Eibl, HJ; Unger, C; Engel, J

Kinetoplastids: related protozoan pathogens, different diseases. (2008) Stuart, Ken; Brun, Reto; Croft, Simon; Fairlamb, Alan; Gürtler, Ricardo E; McKerrow, Jim; Reed, Steve; Tarleton, Rick

A Replicative In Vitro Assay for Drug Discovery against Leishmania donovani. (2016) Tegazzini, Diana; Díaz, Rosario; Aguilar, Fernando; Peña, Imanol; Presa, Jesús L; Yardley, Vanessa; Martin, Julio J; Coteron, Jose M; Croft, Simon L; Cantizani, Juan

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria. (2021) Tempone, Andre G; Pieper, Pauline; Borborema, Samanta ET; Thevenard, Fernanda; Lago, Joao Henrique G; Croft, Simon L; Anderson, Edward A picture_as_pdf

Novel benzoxaborole, nitroimidazole and aminopyrazoles with activity against experimental cutaneous leishmaniasis. (2019) Van Bocxlaer, Katrien; Caridha, Diana; Black, Chad; Vesely, Brian; Leed, Susan; Sciotti, Richard J; Wijnant, Gert-Jan; Yardley, Vanessa; Braillard, Stéphanie; Mowbray, Charles E; Ioset, Jean-Robert; Croft, Simon L

Pharmacokinetics and pharmacodynamics in the treatment of cutaneous leishmaniasis - challenges and opportunities. (2021) Van Bocxlaer, Katrien; Croft, Simon L

Topical Treatment for Cutaneous Leishmaniasis: Dermato-Pharmacokinetic Lead Optimization of Benzoxaboroles. (2018) Van Bocxlaer, Katrien; Gaukel, Eric; Hauser, Deirdre; Park, Seong Hee; Schock, Sara; Yardley, Vanessa; Randolph, Ryan; Plattner, Jacob J; Merchant, Tejal; Croft, Simon L; Jacobs, Robert T; Wring, Stephen A

Film-Forming Systems for the Delivery of DNDI-0690 to Treat Cutaneous Leishmaniasis. (2021) Van Bocxlaer, Katrien; McArthur, Kerri-Nicola; Harris, Andy; Alavijeh, Mo; Braillard, Stéphanie; Mowbray, Charles E; Croft, Simon L

Drug permeation and barrier damage in Leishmania-infected mouse skin. (2016) Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Topical formulations of miltefosine for cutaneous leishmaniasis in a BALB/c mouse model. (2016) Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. (2007) Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL

Plasmodium falciparum: stage specific effects of a selective inhibitor of lactate dehydrogenase. (2005) Vivas, Livia; Easton, Anna; Kendrick, Howard; Cameron, Angus; Lavandera, Jose-Luis; Barros, David; de las Heras, Federico Gomez; Brady, R Leo; Croft, Simon L

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. (2007) Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Bongard, Emily; Robinson, Brian L; Peters, Wallace; Croft, Simon L

Treatment of experimental visceral leishmaniasis with single-dose liposomal amphotericin B - pharmacodynamics and biodistribution at different stages of disease. (2017) Voak, AA; Harris, A; Qaiser, Z; Croft, SL; Seifert, K

Pharmacokinetic / pharmacodynamic relationships of liposomal amphotericin B and miltefosine in experimental visceral leishmaniasis. (2021) Voak, Andrew A; Harris, Andy; Coteron-Lopez, Jose Miguel; Angulo-Barturen, Iñigo; Ferrer-Bazaga, Santiago; Croft, Simon L; Seifert, Karin

Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages. (2018) Voak, Andrew A; Standing, Joseph F; Sepúlveda, Nuno; Harris, Andy; Croft, Simon L; Seifert, Karin

Pharmacokinetics and Pharmacodynamics of the Nitroimidazole DNDI-0690 in Mouse Models of Cutaneous Leishmaniasis. (2019) Wijnant, Gert-Jan; Croft, Simon L; de la Flor, Raul; Alavijeh, Mo; Yardley, Vanessa; Braillard, Stéphanie; Mowbray, Charles; Van Bocxlaer, Katrien

Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B. (2018) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Fortes Francisco, Amanda; Yardley, Vanessa; Harris, Andy; Alavijeh, Mo; Murdan, Sudaxshina; Croft, Simon L

Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome® and AmBisome® in murine cutaneous leishmaniasis. (2018) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Alavijeh, Mo; Silva-Pedrosa, Rita; Antunes, Sandra; Mauricio, Isabel; Murdan, Sudaxshina; Croft, Simon L

Relation between Skin Pharmacokinetics and Efficacy in AmBisome Treatment of Murine Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Harris, Andy; Murdan, Sudaxshina; Croft, Simon L

Efficacy of Paromomycin-Chloroquine Combination Therapy in Experimental Cutaneous Leishmaniasis. (2017) Wijnant, Gert-Jan; Van Bocxlaer, Katrien; Yardley, Vanessa; Murdan, Sudaxshina; Croft, Simon L

Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents. (2001) Wright, CW; Addae-Kyereme, J; Breen, AG; Brown, JE; Cox, MF; Croft, SL; Gökçek, Y; Kendrick, H; Phillips, RM; Pollet, PL

Antiprotozoal activity of sesquiterpenes from Warburgia ugandensis towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. (2008) Wube, AA; Bucar, F; Gibbons, S; Asres, K; Rattray, L; Croft, SL

Antimalarial compounds from Kniphofia foliosa roots. (2005) Wube, Abraham Abebe; Bucar, Franz; Asres, Kaleab; Gibbons, Simon; Rattray, Lauren; Croft, Simon L

Antiprotozoal activity of drimane and coloratane sesquiterpenes towards Trypanosoma brucei rhodesiense and Plasmodium falciparum in vitro. (2010) Wube, Abraham Abebe; Bucar, Franz; Gibbons, Simon; Asres, Kaleab; Rattray, Lauren; Croft, Simon L

China-Africa and China-Asia Collaboration on Schistosomiasis Control: A SWOT Analysis. (2016) Xu, J; Bergquist, R; Qian, YJ; Wang, Q; Yu, Q; Peeling, R; Croft, S; Guo, JG; Zhou, XN

The sensitivity of clinical isolates of Leishmania from Peru and Nepal to miltefosine. (2005) Yardley, Vanessa; Croft, Simon L; De Doncker, Simonne; Dujardin, Jean-Claude; Koirala, Siddhartha; Rijal, Suman; Miranda, Cesar; Llanos-Cuentas, Alejandro; Chappuis, Francois

Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine. (2010) Yardley, Vanessa; Gamarro, Francisco; Croft, Simon L

In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. (2002) Yardley, Vanessa; Khan, Anis A; Martin, Michael B; Slifer, Teri R; Araujo, Fausto G; Moreno, Silvia NJ; Docampo, Roberto; Croft, Simon L; Oldfield, Eric

American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility? (2006) Yardley, Vanessa; Ortuno, Nimer; Llanos-Cuentas, Alejandro; Chappuis, Francois; Doncker, Simonne De; Ramirez, Luis; Croft, Simon; Arevalo, Jorge; Adaui, Vanessa; Bermudez, Hernan; Decuypere, Saskia; Dujardin, Jean-Claude

Terpenoids from Guarea rhophalocarpa. (2001) del Rayo Camacho, M; Phillipson, JD; Croft, SL; Kirby, GC; Warhurst, DC; Solis, PN

Assessment of the Antiprotozoal Activity of <i>Galphimia </i><i>g</i><i>lauca </i>and the Isolation of New Nor-secofriedelanes and Nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C

Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Marley, Dereck; Kirby, Geoffrey C; Warhurst, David C

In vitro activity of Triclisia patens and some bisbenzylisoquinoline alkaloids against Leishmania donovani and Trypanosoma brucei brucei. (2002) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Rock, Peter; Marshall, Sarah J; Schiff, Paul L

In vitro antiprotozoal and cytotoxic activities of some alkaloids, quinones, flavonoids, and coumarins. (2004) del Rayo Camacho, Maria; Phillipson, J David; Croft, Simon L; Yardley, Vanesa; Solis, Pablo N

Anti-African trypanocidal and antimalarial activity of natural flavonoids, dibenzoylmethanes and synthetic analogues. (2009) dos Santos, Djalma AP; de C Braga, Patricia A; da Silva, M Fátima das GF; Fernandes, João B; Vieira, Paulo C; Magalhães, Aderbal F; Magalhães, Eva G; Marsaioli, Anita J; de S Moraes, Valéria R; Rattray, Lauren; Croft, Simon L

Triterpenic acids and flavonoids from Satureja parvifolia. Evaluation of their antiprotozoal activity. (2006) van Baren, C; Anao, I; Lira, PD; Debenedetti, S; Houghton, P; Croft, S; Martino, V

Book Section

Anti-infectives. (2013) Ahmed, A; Ginn, C; Croft, SL; Brocchini, S

Antiprotozoals. (2003) Croft, SL

Leishmaniasis. (2015) Croft, SL; Buffett, P

Antiprotozoal agents. (2010) Croft, SL; Seifert, K

Antiprotozoan drugs. (2001) Croft, SL; Sutherland, C

Natural Products as potential antiparasitic drugs. (2002) Kayser, O; Kiderlen, A; Croft, SL

The relevance of susceptibility tests, breakpoints and markers. (2013) Maes, L; Cos, P; Croft, SL

Conference or Workshop Item

Antiprotozoal activity guided fractionation of Sclerocarya birrea (A. Rich.) Hochst. (2004) Anao, I; Houghton, P; Croft, S

Design, synthesis, and evaluation of taxanes as potential antimalarial agents. (2003) Chen, J; Kuznetsova, L; Chibale, K; Clarkson, C; Smith, P; Croft, SL; Ojima, I

Bisphosphonates as novel chemotherapeutic agents. (2001) Oldfield, E; Martin, MB; Croft, SL; Rodriguez, N; Montalvetti, A; Bailey, BN; Docampo, R; Urbina, JA; Khan, AA; Slifer, TR; Araujo, FG; Moreno, SNJ

Thesis

Treatment of localised cutaneous Leishmania tropica infection in Aleppo, Syria and drug sensitivity of clinical isolates. (2010) Abazid, Nizar

Development of an imaging model of a CNS infection with African trypanosomes. (2015) Burrell-Saward, H

Science and surveillance in the visceral leishmaniasis elimination programme in India. (2022) Dial, NJ

Strategies towards ending the burden of neglected infectious diseases - Assessing the success of the Product Development Partnership model and its approaches. (2024) Katsuno, K

Development of Novel Predictive 2D and 3D in Vitro Models For Anti-Leishmanial Drug Testing. (2018) O'Keeffe, A

Insights into the application of chitosan as an anti-leishmanial compound. (2020) Riezk, A

New pharmacokinetic and PK/PD drug development methodologies for cutaneous leishmaniasis. (2018) Wijnant, GJ

Podcast

New Research Institute Combats Infectious Diseases Globally - 16 December 2011. (2011) UNSPECIFIED audio_file

Other

Leishmaniasis. (2018) Burza, S; Croft, SL; Boelaert, M