In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii

Yardley, V; Khan, AA; Martin, MB; Slifer, TR; Araujo, FG; Moreno, SN; Docampo, R; Croft, SL; Oldfield, E; (2002) In vivo activities of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrobial agents and chemotherapy, 46 (3). pp. 929-31. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.46.3.929-931.2002

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Abstract

Item Type Article
Keywords Administration, Oral, Alendronate/pharmacology, Alkyl and Aryl Transferases/*antagonists & inhibitors, Animal, Diphosphonates/administration & dosage/*therapeutic use, Enzyme Inhibitors/administration & dosage/adverse effects/*therapeutic use, Female, Hamsters, Injections, Intraperitoneal, Leishmania donovani/*drug effects/*enzymology, Leishmaniasis, Visceral/*drug therapy/*parasitology, Mesocricetus, Mice, Mice, Inbred BALB C, Prodrugs/pharmacology, Support, Non-U.S. Gov't, Support, U.S. Gov't, P.H.S., Survival Analysis, Toxoplasma/*drug effects/*enzymology, Toxoplasmosis, Animal/*drug therapy/*parasitology, Administration, Oral, Alendronate, pharmacology, Alkyl and Aryl Transferases, antagonists & inhibitors, Animal, Diphosphonates, administration & dosage, therapeutic use, Enzyme Inhibitors, administration & dosage, adverse effects, therapeutic use, Female, Hamsters, Injections, Intraperitoneal, Leishmania donovani, drug effects, enzymology, Leishmaniasis, Visceral, drug therapy, parasitology, Mesocricetus, Mice, Mice, Inbred BALB C, Prodrugs, pharmacology, Support, Non-U.S. Gov't, Support, U.S. Gov't, P.H.S., Survival Analysis, Toxoplasma, drug effects, enzymology, Toxoplasmosis, Animal, drug therapy, parasitology
Faculty and Department Faculty of Infectious and Tropical Diseases > Department of Infection Biology > Dept of Immunology and Infection (-2019)
Research Centre Leishmaniasis Group
Malaria Centre
Neglected Tropical Diseases Network
PubMed ID 11850291
ISI 173908900054
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