Items where Author is "Lewis, MD"
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Number of items: 23.
2018
Costa, FC;
Francisco, AF;
Jayawardhana, S;
Calderano, SG;
Lewis, MD;
Olmo, F;
Beneke, T;
Gluenz, E;
Sunter, J;
Dean, S;
+2 more...
Kelly, JM;
Taylor, MC;
(2018)
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.
PLoS neglected tropical diseases, 12 (4).
e0006388.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006388
Fortes Francisco, A;
Jayawardhana, S;
Taylor, MC;
Lewis, MD;
Kelly, JM;
(2018)
Assessing the effectiveness of curative benznidazole treatment in preventing chronic cardiac pathology in experimental models of Chagas disease.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00832-18
Lewis, MD;
Francisco, AF;
Jayawardhana, S;
Langston, H;
Taylor, MC;
Kelly, JM;
(2018)
Imaging the development of chronic Chagas disease after oral transmission.
Scientific reports, 8 (1).
p. 11292.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-018-29564-7
MacLean, LM;
Thomas, J;
Lewis, MD;
Cotillo, I;
Gray, DW;
De Rycker, M;
(2018)
Development of Trypanosoma cruzi in vitro assays to identify compounds suitable for progression in Chagas' disease drug discovery.
PLoS neglected tropical diseases, 12 (7).
e0006612.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006612
2017
Acosta, N;
López, E;
Lewis, MD;
Llewellyn, MS;
Gómez, A;
Román, F;
Miles, MA;
Yeo, M;
(2017)
Hosts and vectors of Trypanosoma cruzi discrete typing units in the Chagas disease endemic region of the Paraguayan Chaco.
Parasitology.
pp. 1-15.
ISSN 0031-1820
DOI: https://doi.org/10.1017/S0031182016002663
Campos, MC;
Phelan, J;
Francisco, AF;
Taylor, MC;
Lewis, MD;
Pain, A;
Clark, TG;
Kelly, JM;
(2017)
Genome-wide mutagenesis and multi-drug resistance in American trypanosomes induced by the front-line drug benznidazole.
Scientific reports, 7 (1).
p. 14407.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-017-14986-6
Francisco, AF;
Jayawardhana, S;
Lewis, MD;
Taylor, MC;
Kelly, JM;
(2017)
Biological factors that impinge on Chagas disease drug development.
Parasitology.
pp. 1-10.
ISSN 0031-1820
DOI: https://doi.org/10.1017/S0031182017001469
Louradour, I;
Monteiro, CC;
Inbar, E;
Ghosh, K;
Merkhofer, R;
Lawyer, P;
Paun, A;
Smelkinson, M;
Secundino, N;
Lewis, M;
+3 more...
Erram, D;
Zurek, L;
Sacks, D;
(2017)
The midgut microbiota plays an essential role in sand fly vector competence for Leishmania major.
Cellular microbiology, 19 (10).
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12755
Full text not available from this repository.
2016
Cuypers, B;
Lecordier, L;
Meehan, CJ;
Van den Broeck, F;
Imamura, H;
Büscher, P;
Dujardin, JC;
Laukens, K;
Schnaufer, A;
Dewar, C;
+12 more...
Lewis, M;
Balmer, O;
Azurago, T;
Kyei-Faried, S;
Ohene, SA;
Duah, B;
Homiah, P;
Mensah, EK;
Anleah, F;
Franco, JR;
Pays, E;
Deborggraeve, S;
(2016)
Apolipoprotein L1 Variant Associated with Increased Susceptibility to Trypanosome Infection.
mBio, 7 (2).
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.02198-15
Francisco, AF;
Jayawardhana, S;
Lewis, MD;
White, KL;
Shackleford, DM;
Chen, G;
Saunders, J;
Osuna-Cabello, M;
Read, KD;
Charman, SA;
+2 more...
Chatelain, E;
Kelly, JM;
(2016)
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.
Scientific reports, 6.
p. 35351.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep35351
Lewis, MD;
Francisco, AF;
Taylor, MC;
Jayawardhana, S;
Kelly, JM;
(2016)
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.
Cellular microbiology.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12584
Lewis, MD;
Kelly, JM;
(2016)
Putting Infection Dynamics at the Heart of Chagas Disease.
Trends in parasitology.
ISSN 1471-4922
DOI: https://doi.org/10.1016/j.pt.2016.08.009
Shender, LA;
Lewis, MD;
Rejmanek, D;
Mazet, JA;
(2016)
Molecular Diversity of Trypanosoma cruzi Detected in the Vector Triatoma protracta from California, USA.
PLoS neglected tropical diseases, 10 (1).
e0004291.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0004291
2015
Carnes, J;
Anupama, A;
Balmer, O;
Jackson, A;
Lewis, M;
Brown, R;
Cestari, I;
Desquesnes, M;
Gendrin, C;
Hertz-Fowler, C;
+17 more...
Imamura, H;
Ivens, A;
Kořený, L;
Lai, DH;
MacLeod, A;
McDermott, SM;
Merritt, C;
Monnerat, S;
Moon, W;
Myler, P;
Phan, I;
Ramasamy, G;
Sivam, D;
Lun, ZR;
Lukeš, J;
Stuart, K;
Schnaufer, A;
(2015)
Genome and Phylogenetic Analyses of Trypanosoma evansi Reveal Extensive Similarity to T. brucei and Multiple Independent Origins for Dyskinetoplasty.
PLoS neglected tropical diseases, 9 (1).
e3404.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0003404
Fortes Francisco, A;
Lewis, MD;
Jayawardhana, S;
Taylor, MC;
Chatelain, E;
Kelly, JM;
(2015)
The limited ability of posaconazole to cure both acute and chronic Trypanosoma cruzi infections revealed by highly sensitive in vivo imaging.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00520-15
Francisco, AF;
Lewis, MD;
Jayawardhana, S;
Taylor, MC;
Chatelain, E;
Kelly, JM;
(2015)
Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs".
Antimicrobial agents and chemotherapy, 59 (12).
p. 7925.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.02022-15
Full text not available from this repository.
Taylor, MC;
Lewis, MD;
Francisco, AF;
Wilkinson, SR;
Kelly, JM;
(2015)
The Trypanosoma cruzi Vitamin C Dependent Peroxidase Confers Protection against Oxidative Stress but Is Not a Determinant of Virulence.
PLoS neglected tropical diseases, 9 (4).
e0003707.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0003707
2014
Bhattacharyya, T;
Falconar, AK;
Luquetti, AO;
Costales, JA;
Grijalva, MJ;
Lewis, MD;
Messenger, LA;
Tran, TT;
Ramirez, JD;
Guhl, F;
+5 more...
Carrasco, HJ;
Diosque, P;
Garcia, L;
Litvinov, SV;
Miles, MA;
(2014)
Development of Peptide-based lineage-specific serology for chronic chagas disease: geographical and clinical distribution of epitope recognition.
PLoS neglected tropical diseases, 8 (5).
e2892.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0002892
Diosque, P;
Tomasini, N;
Lauthier, JJ;
Messenger, LA;
Monje Rumi, MM;
Ragone, PG;
Alberti-D'Amato, AM;
Pérez Brandán, C;
Barnabé, C;
Tibayrenc, M;
+4 more...
Lewis, MD;
Llewellyn, MS;
Miles, MA;
Yeo, M;
(2014)
Optimized Multilocus Sequence Typing (MLST) Scheme for Trypanosoma cruzi.
PLoS neglected tropical diseases, 8 (8).
e3117.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0003117
Gelanew, T;
Hailu, A;
Schőnian, G;
Lewis, MD;
Miles, MA;
Yeo, M;
(2014)
Multilocus sequence and microsatellite identification of intra-specific hybrids and ancestor-like donors among natural Ethiopian isolates of Leishmania donovani.
International journal for parasitology.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2014.05.008
Lewis, MD;
Fortes Francisco, A;
Taylor, MC;
Burrell-Saward, H;
McLatchie, AP;
Miles, MA;
Kelly, JM;
(2014)
Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection.
Cellular microbiology, 16 (9).
pp. 1285-300.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12297
Lewis, MD;
Francisco, AF;
Taylor, MC;
Kelly, JM;
(2014)
A New Experimental Model for Assessing Drug Efficacy against Trypanosoma cruzi Infection Based on Highly Sensitive In Vivo Imaging.
Journal of biomolecular screening, 20 (1).
pp. 36-43.
ISSN 1087-0571
DOI: https://doi.org/10.1177/1087057114552623
2011
Lewis, MD;
Llewellyn, MS;
Yeo, M;
Acosta, N;
Gaunt, MW;
Miles, MA;
(2011)
Recent, Independent and Anthropogenic Origins of Trypanosoma cruzi Hybrids.
PLoS neglected tropical diseases, 5 (10).
e1363.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0001363