Items where Author is "Jayawardhana, S"
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Number of items: 10.
2018
Costa, FC;
Francisco, AF;
Jayawardhana, S;
Calderano, SG;
Lewis, MD;
Olmo, F;
Beneke, T;
Gluenz, E;
Sunter, J;
Dean, S;
+2 more...
Kelly, JM;
Taylor, MC;
(2018)
Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping.
PLoS neglected tropical diseases, 12 (4).
e0006388.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006388
Fortes Francisco, A;
Jayawardhana, S;
Taylor, MC;
Lewis, MD;
Kelly, JM;
(2018)
Assessing the effectiveness of curative benznidazole treatment in preventing chronic cardiac pathology in experimental models of Chagas disease.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00832-18
Lewis, MD;
Francisco, AF;
Jayawardhana, S;
Langston, H;
Taylor, MC;
Kelly, JM;
(2018)
Imaging the development of chronic Chagas disease after oral transmission.
Scientific reports, 8 (1).
p. 11292.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-018-29564-7
2017
Brand, S;
Ko, EJ;
Viayna, E;
Thompson, S;
Spinks, D;
Thomas, M;
Sandberg, L;
Francisco, AF;
Jayawardhana, S;
Smith, VC;
+26 more...
Jansen, C;
De Rycker, M;
Thomas, J;
MacLean, L;
Osuna-Cabello, M;
Riley, J;
Scullion, P;
Stojanovski, L;
Simeons, FRC;
Epemolu, O;
Shishikura, Y;
Crouch, SD;
Bakshi, TS;
Nixon, CJ;
Reid, IH;
Hill, AP;
Underwood, TZ;
Hindley, SJ;
Robinson, SA;
Kelly, JM;
Fiandor, JM;
Wyatt, PG;
Marco, M;
Miles, TJ;
Read, KD;
Gilbert, IH;
(2017)
Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi.
Journal of medicinal chemistry.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00463
Francisco, AF;
Jayawardhana, S;
Lewis, MD;
Taylor, MC;
Kelly, JM;
(2017)
Biological factors that impinge on Chagas disease drug development.
Parasitology.
pp. 1-10.
ISSN 0031-1820
DOI: https://doi.org/10.1017/S0031182017001469
2016
Francisco, AF;
Jayawardhana, S;
Lewis, MD;
White, KL;
Shackleford, DM;
Chen, G;
Saunders, J;
Osuna-Cabello, M;
Read, KD;
Charman, SA;
+2 more...
Chatelain, E;
Kelly, JM;
(2016)
Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage.
Scientific reports, 6.
p. 35351.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep35351
Kishore, KG;
Ghashghaei, O;
Estarellas, C;
Mestre, MM;
Monturiol, C;
Kielland, N;
Kelly, JM;
Francisco, AF;
Jayawardhana, S;
Muñoz-Torrero, D;
+4 more...
Pérez, B;
Luque, FJ;
Gámez-Montaño, R;
Lavilla, R;
(2016)
Insertion of Isocyanides into N-Si Bonds: Multicomponent Reactions with Azines Leading to Potent Antiparasitic Compounds.
Angewandte Chemie (International ed in English), 55 (31).
pp. 8994-8.
ISSN 1433-7851
DOI: https://doi.org/10.1002/anie.201604109
Full text not available from this repository.
Lewis, MD;
Francisco, AF;
Taylor, MC;
Jayawardhana, S;
Kelly, JM;
(2016)
Host and parasite genetics shape a link between Trypanosoma cruzi infection dynamics and chronic cardiomyopathy.
Cellular microbiology.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12584
2015
Fortes Francisco, A;
Lewis, MD;
Jayawardhana, S;
Taylor, MC;
Chatelain, E;
Kelly, JM;
(2015)
The limited ability of posaconazole to cure both acute and chronic Trypanosoma cruzi infections revealed by highly sensitive in vivo imaging.
Antimicrobial agents and chemotherapy.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00520-15
Francisco, AF;
Lewis, MD;
Jayawardhana, S;
Taylor, MC;
Chatelain, E;
Kelly, JM;
(2015)
Reply to "Drug Susceptibility of Genetically Engineered Trypanosoma cruzi Strains and Sterile Cure in Animal Models as a Criterion for Potential Clinical Efficacy of Anti-T. cruzi Drugs".
Antimicrobial agents and chemotherapy, 59 (12).
p. 7925.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.02022-15
Full text not available from this repository.