Items where Author is "Blackman, MJ"
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Number of items: 33.
2018
Deligianni, E;
Silmon de Monerri, NC;
McMillan, PJ;
Bertuccini, L;
Superti, F;
Manola, M;
Spanos, L;
Louis, C;
Blackman, MJ;
Tilley, L;
+1 more...
Siden-Kiamos, I;
(2018)
Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage.
PloS one, 13 (8).
e0201651.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0201651
Herman, LS;
Fornace, K;
Phelan, J;
Grigg, MJ;
Anstey, NM;
William, T;
Moon, RW;
Blackman, MJ;
Drakeley, CJ;
Tetteh, KKA;
(2018)
Identification and validation of a novel panel of Plasmodium knowlesi biomarkers of serological exposure.
PLoS neglected tropical diseases, 12 (6).
e0006457.
ISSN 1935-2727
DOI: https://doi.org/10.1371/journal.pntd.0006457
Perrin, AJ;
Collins, CR;
Russell, MRG;
Collinson, LM;
Baker, DA;
Blackman, MJ;
(2018)
The Actinomyosin Motor Drives Malaria Parasite Red Blood Cell Invasion but Not Egress.
mBio, 9 (4).
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.00905-18
Thomas, JA;
Tan, MYS;
Bisson, C;
Borg, A;
Umrekar, TR;
Hackett, F;
Hale, VL;
Vizcay-Barrena, G;
Fleck, RA;
Snijders, AP;
+2 more...
Saibil, HR;
Blackman, MJ;
(2018)
A protease cascade regulates release of the human malaria parasite Plasmodium falciparum from host red blood cells.
Nature microbiology.
ISSN 2058-5276
DOI: https://doi.org/10.1038/s41564-018-0111-0
2017
Benavente, ED;
de Sessions, PF;
Moon, RW;
Grainger, M;
Holder, AA;
Blackman, MJ;
Roper, C;
Drakeley, CJ;
Pain, A;
Sutherland, CJ;
+3 more...
Hibberd, ML;
Campino, S;
Clark, TG;
(2017)
A reference genome and methylome for the Plasmodium knowlesi A1-H.1 line.
International journal for parasitology.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2017.09.008
Collins, CR;
Hackett, F;
Atid, J;
Tan, MSY;
Blackman, MJ;
(2017)
The Plasmodium falciparum pseudoprotease SERA5 regulates the kinetics and efficiency of malaria parasite egress from host erythrocytes.
PLoS pathogens, 13 (7).
e1006453.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1006453
Diez Benavente, E;
Florez de Sessions, P;
Moon, RW;
Holder, AA;
Blackman, MJ;
Roper, C;
Drakeley, CJ;
Pain, A;
Sutherland, CJ;
Hibberd, ML;
+2 more...
Campino, S;
Clark, TG;
(2017)
Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations.
PLoS genetics, 13 (9).
e1007008.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1007008
Hale, VL;
Watermeyer, JM;
Hackett, F;
Vizcay-Barrena, G;
van Ooij, C;
Thomas, JA;
Spink, MC;
Harkiolaki, M;
Duke, E;
Fleck, RA;
+2 more...
Blackman, MJ;
Saibil, HR;
(2017)
Parasitophorous vacuole poration precedes its rupture and rapid host erythrocyte cytoskeleton collapse in Plasmodium falciparum egress.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1619441114
Pino, P;
Caldelari, R;
Mukherjee, B;
Vahokoski, J;
Klages, N;
Maco, B;
Collins, CR;
Blackman, MJ;
Kursula, I;
Heussler, V;
+2 more...
Brochet, M;
Soldati-Favre, D;
(2017)
A multistage antimalarial targets the plasmepsins IX and X essential for invasion and egress.
Technical Report.
American Association for the Advancement of Science.
DOI: https://doi.org/10.1126/science.aaf8675
2016
Hill, RJ;
Ringel, A;
Knuepfer, E;
Moon, RW;
Blackman, MJ;
van Ooij, C;
(2016)
Regulation and essentiality of the START-domain-containing phospholipid transfer protein PFA0210c in malaria parasites.
The Journal of biological chemistry, 291 (46).
pp. 24280-24292.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M116.740506
Jones, ML;
Das, S;
Belda, H;
Collins, CR;
Blackman, MJ;
Treeck, M;
(2016)
A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum.
Scientific reports, 6.
p. 21800.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep21800
Moon, RW;
Sharaf, H;
Hastings, CH;
Ho, YS;
Nair, MB;
Rchiad, Z;
Knuepfer, E;
Ramaprasad, A;
Mohring, F;
Amir, A;
+7 more...
Yusuf, NA;
Hall, J;
Almond, N;
Lau, YL;
Pain, A;
Blackman, MJ;
Holder, AA;
(2016)
Normocyte-binding protein required for human erythrocyte invasion by the zoonotic malaria parasite Plasmodium knowlesi.
Proceedings of the National Academy of Sciences of the United States of America.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1522469113
Thomas, JA;
Collins, CR;
Das, S;
Hackett, F;
Graindorge, A;
Bell, D;
Deu, E;
Blackman, MJ;
(2016)
Development and Application of a Simple Plaque Assay for the Human Malaria Parasite Plasmodium falciparum.
PloS one, 11 (6).
e0157873.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0157873
2015
Das, S;
Hertrich, N;
Perrin, AJ;
Withers-Martinez, C;
Collins, CR;
Jones, ML;
Watermeyer, JM;
Fobes, ET;
Martin, SR;
Saibil, HR;
+4 more...
Wright, GJ;
Treeck, M;
Epp, C;
Blackman, MJ;
(2015)
Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs.
Cell host & microbe, 18 (4).
pp. 433-44.
ISSN 1931-3128
DOI: https://doi.org/10.1016/j.chom.2015.09.007
Pieperhoff, MS;
Pall, GS;
Jiménez-Ruiz, E;
Das, S;
Melatti, C;
Gow, M;
Wong, EH;
Heng, J;
Müller, S;
Blackman, MJ;
+1 more...
Meissner, M;
(2015)
Conditional U1 Gene Silencing in Toxoplasma gondii.
PloS one, 10 (6).
e0130356.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0130356
Stallmach, R;
Kavishwar, M;
Withers-Martinez, C;
Hackett, F;
Collins, CR;
Howell, SA;
Yeoh, S;
Knuepfer, E;
Atid, AJ;
Holder, AA;
+1 more...
Blackman, MJ;
(2015)
Plasmodium falciparum SERA5 plays a non-enzymatic role in the malarial asexual blood-stage lifecycle.
Molecular microbiology, 96 (2).
pp. 368-87.
ISSN 0950-382X
DOI: https://doi.org/10.1111/mmi.12941
Watermeyer, JM;
Hale, VL;
Hackett, F;
Clare, DK;
Cutts, EE;
Vakonakis, I;
Fleck, RA;
Blackman, MJ;
Saibil, HR;
(2015)
A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum-infected erythrocytes.
Blood, 127 (3).
pp. 343-351.
ISSN 0006-4971
DOI: https://doi.org/10.1182/blood-2015-10-674002
2014
Giovani, S;
Penzo, M;
Brogi, S;
Brindisi, M;
Gemma, S;
Novellino, E;
Savini, L;
Blackman, MJ;
Campiani, G;
Butini, S;
(2014)
Rational design of the first difluorostatone-based PfSUB1 inhibitors.
Bioorganic & medicinal chemistry letters, 24 (15).
pp. 3582-6.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2014.05.044
Full text not available from this repository.
Grüring, C;
Moon, RW;
Lim, C;
Holder, AA;
Blackman, MJ;
Duraisingh, MT;
(2014)
Human red blood cell-adapted Plasmodium knowlesi parasites: a new model system for malaria research.
Cellular microbiology.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12275
Full text not available from this repository.
Jaudzems, K;
Tars, K;
Maurops, G;
Ivdra, N;
Otikovs, M;
Leitans, J;
Kanepe-Lapsa, I;
Domraceva, I;
Mutule, I;
Trapencieris, P;
+2 more...
Blackman, MJ;
Jirgensons, A;
(2014)
Plasmepsin inhibitory activity and structure-guided optimization of a potent hydroxyethylamine-based antimalarial hit.
ACS medicinal chemistry letters, 5 (4).
pp. 373-7.
ISSN 1948-5875
DOI: https://doi.org/10.1021/ml4004952
Full text not available from this repository.
Kher, SS;
Penzo, M;
Fulle, S;
Finn, PW;
Blackman, MJ;
Jirgensons, A;
(2014)
Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1.
Bioorganic & medicinal chemistry letters.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2014.07.086
Withers-Martinez, C;
Strath, M;
Hackett, F;
Haire, LF;
Howell, SA;
Walker, PA;
Christodoulou, E;
Evangelos, C;
Dodson, GG;
Blackman, MJ;
(2014)
The malaria parasite egress protease SUB1 is a calcium-dependent redox switch subtilisin.
Nature communications, 5.
p. 3726.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms4726
2013
Suarez, C;
Volkmann, K;
Gomes, AR;
Billker, O;
Blackman, MJ;
(2013)
The malarial serine protease SUB1 plays an essential role in parasite liver stage development.
PLoS pathogens, 9 (12).
e1003811.
ISSN 1553-7366
DOI: https://doi.org/10.1371/journal.ppat.1003811
2012
Withers-Martinez, C;
Suarez, C;
Fulle, S;
Kher, S;
Penzo, M;
Ebejer, JP;
Koussis, K;
Hackett, F;
Jirgensons, A;
Finn, P;
+1 more...
Blackman, MJ;
(2012)
Plasmodium subtilisin-like protease 1 (SUB1): insights into the active-site structure, specificity and function of a pan-malaria drug target.
International journal for parasitology, 42 (6).
pp. 597-612.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.04.005
2010
Friedrich, N;
Santos, JM;
Liu, Y;
Palma, AS;
Leon, E;
Saouros, S;
Kiso, M;
Blackman, MJ;
Matthews, S;
Feizi, T;
+1 more...
Soldati-Favre, D;
(2010)
Members of a novel protein family containing microneme adhesive repeat domains act as sialic acid-binding lectins during host cell invasion by apicomplexan parasites.
The Journal of biological chemistry, 285 (3).
pp. 2064-76.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M109.060988
Full text not available from this repository.
2007
Yeoh, S;
O'Donnell, RA;
Koussis, K;
Dluzewski, AR;
Ansell, KH;
Osborne, SA;
Hackett, F;
Withers-Martinez, C;
Mitchell, GH;
Bannister, LH;
+3 more...
Bryans, JS;
Kettleborough, CA;
Blackman, MJ;
(2007)
Subcellular discharge of a serine protease mediates release of invasive malaria parasites from host erythrocytes.
Cell, 131 (6).
pp. 1072-83.
ISSN 0092-8674
DOI: https://doi.org/10.1016/j.cell.2007.10.049
2005
Johansson, PO;
Lindberg, J;
Blackman, MJ;
Kvarnström, I;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
Samuelsson, B;
(2005)
Design and synthesis of potent inhibitors of plasmepsin I and II: X-ray crystal structure of inhibitor in complex with plasmepsin II.
Journal of medicinal chemistry, 48 (13).
pp. 4400-9.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm040884n
Full text not available from this repository.
2004
Ersmark, K;
Feierberg, I;
Bjelic, S;
Hamelink, E;
Hackett, F;
Blackman, MJ;
Hultén, J;
Samuelsson, B;
Aqvist, J;
Hallberg, A;
(2004)
Potent inhibitors of the Plasmodium falciparum enzymes plasmepsin I and II devoid of cathepsin D inhibitory activity.
Journal of medicinal chemistry, 47 (1).
pp. 110-22.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030933g
Full text not available from this repository.
Johansson, PO;
Chen, Y;
Belfrage, AK;
Blackman, MJ;
Kvarnström, I;
Jansson, K;
Vrang, L;
Hamelink, E;
Hallberg, A;
Rosenquist, A;
+1 more...
Samuelsson, B;
(2004)
Design and synthesis of potent inhibitors of the malaria aspartyl proteases plasmepsin I and II. Use of solid-phase synthesis to explore novel statine motifs.
Journal of medicinal chemistry, 47 (13).
pp. 3353-66.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm031106i
Full text not available from this repository.
2003
Howell, SA;
Well, I;
Fleck, SL;
Kettleborough, C;
Collins, CR;
Blackman, MJ;
(2003)
A single malaria merozoite serine protease mediates shedding of multiple surface proteins by juxtamembrane cleavage.
The Journal of biological chemistry, 278 (26).
pp. 23890-8.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M302160200
Full text not available from this repository.
2002
Withers-Martinez, C;
Saldanha, JW;
Ely, B;
Hackett, F;
O'Connor, T;
Blackman, MJ;
(2002)
Expression of recombinant Plasmodium falciparum subtilisin-like protease-1 in insect cells. Characterization, comparison with the parasite protease, and homology modeling.
The Journal of biological chemistry, 277 (33).
pp. 29698-709.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M203088200
Full text not available from this repository.
2001
Miller, SA;
Binder, EM;
Blackman, MJ;
Carruthers, VB;
Kim, K;
(2001)
A conserved subtilisin-like protein TgSUB1 in microneme organelles of Toxoplasma gondii.
The Journal of biological chemistry, 276 (48).
pp. 45341-8.
ISSN 0021-9258
DOI: https://doi.org/10.1074/jbc.M106665200
Full text not available from this repository.