Etiology of severe childhood pneumonia in The Gambia West Africa determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.


Howie, SR; Morris, GA; Tokarz, R; Ebruke, BE; Machuka, EM; Ideh, RC; Chimah, O; Secka, O; Townend, J; Dione, M; Oluwalana, C; Njie, M; Jallow, M; Hill, PC; Antonio, M; Greenwood, B; Briese, T; Mulholland, K; Corrah, T; Lipkin, WI; Adegbola, RA; (2014) Etiology of severe childhood pneumonia in The Gambia West Africa determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples. Clinical infectious diseases , 59 (5). pp. 682-5. ISSN 1058-4838 DOI: 10.1093/cid/ciu384

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Abstract

: Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines. Multiple pathogens were detected frequently, notably Haemophilus influenzae (mostly nontypeable) together with S. pneumoniae.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Disease Control
Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Centre for Maternal, Reproductive and Child Health (MARCH)
PubMed ID: 24867789
Web of Science ID: 342921100017
URI: http://researchonline.lshtm.ac.uk/id/eprint/1775888

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