Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Howie, Stephen RC;
Morris, Gerard AJ;
Tokarz, Rafal;
Ebruke, Bernard E;
Machuka, Eunice M;
Ideh, Readon C;
Chimah, Osaretin;
Secka, Ousman;
Townend, John;
Dione, Michel;
+11 more...Oluwalana, Claire;
Njie, Malick;
Jallow, Mariatou;
Hill, Philip C;
Antonio, Martin;
Greenwood, Brian;
Briese, Thomas;
Mulholland, Kim;
Corrah, Tumani;
Lipkin, W Ian;
Adegbola, Richard A;
(2014)
Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Clinical infectious diseases, 59 (5).
pp. 682-685.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/ciu384
Permanent Identifier
Use this Digital Object Identifier when citing or linking to this resource.
Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines. Multiple pathogens were detected frequently, notably Haemophilus influenzae (mostly nontypeable) together with S. pneumoniae.