Optimizing bioluminescence imaging to study protozoan parasite infections.


Taylor, MC; Kelly, JM; (2014) Optimizing bioluminescence imaging to study protozoan parasite infections. Trends in parasitology, 30 (4). pp. 161-2. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2014.01.006

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Abstract

: Bioluminescence imaging is a non-invasive technique which can be used to monitor infections in real-time. However, its utility is restricted by difficulties in detecting pathogens in deep tissue. 'Red-shifted' luciferases, which emit light of longer wavelength than standard bioluminescence-generating proteins, greatly enhance sensitivity, and have wide applicability for studying parasite infections.<br/>

Item Type: Article
Faculty and Department: Faculty of Infectious and Tropical Diseases > Dept of Pathogen Molecular Biology
PubMed ID: 24485045
Web of Science ID: 335296500001
URI: http://researchonline.lshtm.ac.uk/id/eprint/1520180

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