Items where Research Centre is "TB Centre"

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Number of items: 58.

2020

Aguilar-López, Bruno A; Moreno-Altamirano, María Maximina Bertha; Dockrell, Hazel M; Duchen, Michael R; Sánchez-García, Francisco Javier; (2020) Mitochondria: An Integrative Hub Coordinating Circadian Rhythms, Metabolism, the Microbiome, and Immunity. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 8. 51-. ISSN 2296-634X DOI: https://doi.org/10.3389/fcell.2020.00051
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Andreas, Nicholas J; Basu Roy, Robindra; Gomez-Romero, Maria; Horneffer-van der Sluis, Verena; Lewis, Matthew R; Camuzeaux, Stephane SM; Jiménez, Beatriz; Posma, Joram M; Tientcheu, Leopold; Egere, Uzochukwu; +4 more... Sillah, Abdou; Togun, Toyin; Holmes, Elaine; Kampmann, Beate; (2020) Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis. Scientific reports, 10 (1). 7302-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-020-64413-6
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Auld, Andrew F; Agizew, Tefera; Mathoma, Anikie; Boyd, Rosanna; Date, Anand; Pals, Sherri L; Serumola, Christopher; Mathebula, Unami; Alexander, Heather; Ellerbrock, Tedd V; +6 more... Rankgoane-Pono, Goabaone; Pono, Pontsho; Shepherd, James C; Fielding, Katherine; Grant, Alison D; Finlay, Alyssa; (2020) Effect of tuberculosis screening and retention interventions on early antiretroviral therapy mortality in Botswana: a stepped-wedge cluster randomized trial. BMC Med, 18 (1). 19-. DOI: https://doi.org/10.1186/s12916-019-1489-0
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Basu Roy, Robindra; Thee, Stephanie; Blázquez-Gamero, Daniel; Falcón-Neyra, Lola; Neth, Olaf; Noguera-Julian, Antoni; Lillo, Cristina; Galli, Luisa; Venturini, Elisabetta; Buonsenso, Danilo; +10 more... Götzinger, Florian; Martinez-Alier, Nuria; Velizarova, Svetlana; Brinkmann, Folke; Welch, Steven B; Tsolia, Maria; Santiago-Garcia, Begoña; Krüger, Renate; Tebruegge, Marc; ptbnet TB Meningitis Study Group; (2020) Performance of immune-based and microbiological tests in children with tuberculosis meningitis in Europe: a multicentre Paediatric Tuberculosis Network European Trials Group (ptbnet) study. The European respiratory journal, 56 (1). p. 1902004. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.02004-2019
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Beckert, Patrick; Sanchez-Padilla, Elisabeth; Merker, Matthias; Dreyer, Viola; Kohl, Thomas A; Utpatel, Christian; Köser, Claudio U; Barilar, Ivan; Ismail, Nazir; Omar, Shaheed Vally; +13 more... Klopper, Marisa; Warren, Robin M; Hoffmann, Harald; Maphalala, Gugu; Ardizzoni, Elisa; de Jong, Bouke C; Kerschberger, Bernhard; Schramm, Birgit; Andres, Sönke; Kranzer, Katharina; Maurer, Florian P; Bonnet, Maryline; Niemann, Stefan; (2020) MDR M. tuberculosis outbreak clone in Eswatini missed by Xpert has elevated bedaquiline resistance dated to the pre-treatment era. GENOME MEDICINE, 12 (1). 104-. ISSN 1756-994X DOI: https://doi.org/10.1186/s13073-020-00793-8
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Cattamanchi, Adithya; Berger, Christopher A; Shete, Priya B; Turyahabwe, Stavia; Joloba, Moses; Moore, David Aj; Davis, Lucian J; Katamba, Achilles; (2020) Implementation science to improve the quality of tuberculosis diagnostic services in Uganda. Journal of clinical tuberculosis and other mycobacterial diseases, 18. 100136-. ISSN 2405-5794 DOI: https://doi.org/10.1016/j.jctube.2019.100136
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Conceição, Marília Lima da; Conceição, Emilyn Costa; Furlaneto, Ismari Perini; Silva, Sandro Patroca da; Guimarães, Arthur Emil Dos Santos; Gomes, Pedro; Boschiroli, María Laura; Michelet, Lorraine; Kohl, Thomas Andreas; Kranzer, Katharina; +5 more... Francez, Loreno da Costa; Lima, Luana Nepomuceno Gondim Costa; Portugal, Isabel; Perdigão, João; Lima, Karla Valéria Batista; (2020) Phylogenomic Perspective on a Unique Mycobacterium bovis Clade Dominating Bovine Tuberculosis Infections among Cattle and Buffalos in Northern Brazil. Scientific reports, 10 (1). 1747-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-020-58398-5
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Cox, V; McKenna, L; Acquah, R; Reuter, A; Wasserman, S; Vambe, D; Ustero, P; Udwadia, Z; Triviño-Duran, L; Tommasi, M; +15 more... Skrahina, A; Seddon, JA; Rodolfo, R; Rich, M; Padanilam, X; Oyewusi, L; Ohler, L; Lungu, P; Loveday, M; Khan, U; Khan, P; Hughes, J; Hewison, C; Guglielmetti, L; Furin, J; (2020) Clinical perspectives on treatment of rifampicin-resistant/multidrug-resistant TB. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 24 (11). pp. 1134-1144. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.20.0330
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Der, Joyce B; Grint, Daniel J; Narh, Clement T; Bonsu, Frank; Grant, Alison D; (2020) Missed opportunities for tuberculosis investigation in a municipal hospital in Ghana: evidence from patient exit interviews. Transactions of the Royal Society of Tropical Medicine and Hygiene, 115 (1). pp. 43-50. ISSN 0035-9203 DOI: https://doi.org/10.1093/trstmh/traa080
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Frascella, Beatrice; Richards, Alexandra S; Sossen, Bianca; Emery, Jon C; Odone, Anna; Law, Irwin; Onozaki, Ikushi; Esmail, Hanif; Houben, Rein MGJ; (2020) Subclinical Tuberculosis Disease-A Review and Analysis of Prevalence Surveys to Inform Definitions, Burden, Associations, and Screening Methodology. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73 (3). e830-e841. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciaa1402
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Grandjean, Louis; Monteserin, Joha; Gilman, Robert; Pauschardt, Julia; Rokadiya, Sakib; Bonilla, Cesar; Ritacco, Viviana; Vidal, Julia Rios; Parkhill, Julian; Peacock, Sharon; +2 more... Moore, David Aj; Balloux, Francois; (2020) Association between bacterial homoplastic variants and radiological pathology in tuberculosis. THORAX, 75 (7). pp. 584-591. ISSN 0040-6376 DOI: https://doi.org/10.1136/thoraxjnl-2019-213281
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Harris, Rebecca C; Sumner, Tom; Knight, Gwenan M; Zhang, Hui; White, Richard G; (2020) Potential impact of tuberculosis vaccines in China, South Africa, and India. Science Translational Medicine, 12 (564). eaax4607-eaax4607. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aax4607
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Hill, J; Dickson-Hall, L; Grant, AD; Grundy, C; Black, J; Kielmann, K; Mlisana, K; Mitrani, L; Loveday, M; Moshabela, M; +4 more... Le Roux, S; Jassat, W; Nicol, M; Cox, H; (2020) Drug-resistant tuberculosis patient care journeys in South Africa: a pilot study using routine laboratory data. INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, 24 (1). pp. 83-91. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.19.0100
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Houben, Rein; Parwati, Cicilia Gita; Farid, Muhammad Noor; Nasution, Helmi Suryani; Sulistyo, Sulistyo; Basri, Carmelia; Gebhard, Agnes; Tiemersma, Edine; Pambudi, Imran; Surya, Asik; (2020) Subnational burden estimation in Tuberculosis: generation and application of a new tool in Indonesia. International Journal of Tuberculosis and Lung Disease, 24 (2). pp. 250-257. ISSN 1027-3719 https://researchonline.lshtm.ac.uk/id/eprint/4655392
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Katale, Bugwesa Z; Mbelele, Peter M; Lema, Nsiande A; Campino, Susana; Mshana, Stephen E; Rweyemamu, Mark M; Phelan, Jody E; Keyyu, Julius D; Majigo, Mtebe; Mbugi, Erasto V; +4 more... Dockrell, Hazel M; Clark, Taane G; Matee, Mecky I; Mpagama, Stellah; (2020) Whole genome sequencing of Mycobacterium tuberculosis isolates and clinical outcomes of patients treated for multidrug-resistant tuberculosis in Tanzania. BMC GENOMICS, 21 (1). 174-. ISSN 1471-2164 DOI: https://doi.org/10.1186/s12864-020-6577-1
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Khan, Palwasha Y; Paracha, M Shariq; Grundy, Chris; Saeed, Saadia; Dojki, Maqboola; Madhani, Falak; Page-Shipp, Liesl; Khursheed, Nazia; Rabbani, Waleed; Riaz, Najam; +9 more... Khowaja, Saira; Hussain, Owais; Habib, Ali; Khan, Uzma; Kranzer, Katharina; Ferrand, Rashida A; Lewis, James J; Khan, Aamir J; Fielding, Katherine L; (2020) Concurrent adult pulmonary tuberculosis prevalence survey using digital radiography and Xpert MTB/RIF Ultra and child interferon-gamma release assay Mycobacterium tuberculosis infection survey in Karachi, Pakistan: a study protocol. F1000 Research Ltd. DOI: https://doi.org/10.12688/wellcomeopenres.15963.1
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Kielmann, Karina; Karat, Aaron S; Zwama, Gimenne; Colvin, Christopher; Swartz, Alison; Voce, Anna S; Yates, Tom A; MacGregor, Hayley; McCreesh, Nicky; Kallon, Idriss; +4 more... Vassall, Anna; Govender, Indira; Seeley, Janet; Grant, Alison D; (2020) Tuberculosis infection prevention and control: why we need a whole systems approach. Infectious diseases of poverty, 9 (1). 56-. ISSN 2095-5162 DOI: https://doi.org/10.1186/s40249-020-00667-6
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Kohl, Thomas A; Kranzer, Katharina; Andres, Sönke; Wirth, Thierry; Niemann, Stefan; Moser, Irmgard; (2020) Population Structure of Mycobacterium bovis in Germany: a Long-Term Study Using Whole-Genome Sequencing Combined with Conventional Molecular Typing Methods. Journal of clinical microbiology, 58 (11). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.01573-20
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Kwan, Philip Kam Weng; Periaswamy, Balamurugan; De Sessions, Paola Florez; Lin, Wenwei; Molton, James S; Naftalin, Claire M; Naim, Ahmad Nazri Mohamed; Hibberd, Martin L; Paton, Nicholas I; (2020) A blood RNA transcript signature for TB exposure in household contacts. BMC INFECTIOUS DISEASES, 20 (1). 403-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-020-05116-1
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Lubbers, Rosalie; Sutherland, Jayne S; Goletti, Delia; de Paus, Roelof A; Dijkstra, Douwe J; van Moorsel, Coline HM; Veltkamp, Marcel; Vestjens, Stefan MT; Bos, Willem JW; Petrone, Linda; +8 more... Malherbe, Stephanus T; Walzl, Gerhard; Gelderman, Kyra A; Groeneveld, Geert H; Geluk, Annemieke; Ottenhoff, Tom HM; Joosten, Simone A; Trouw, Leendert A; (2020) Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients. MOLECULAR IMMUNOLOGY, 120. pp. 187-195. ISSN 0161-5890 DOI: https://doi.org/10.1016/j.molimm.2020.02.006
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Lubyayi, Lawrence; Mawa, Patrice A; Nabakooza, Grace; Nakibuule, Marjorie; Tushabe, John Vianney; Serubanja, Joel; Aibo, Dorothy; Akurut, Hellen; Tumusiime, Josephine; Hasso-Agopsowicz, Mateusz; +7 more... Kaleebu, Pontiano; Levin, Jonathan; Dockrell, Hazel M; Smith, Steven; Webb, Emily L; Elliott, Alison M; Cose, Stephen; (2020) Maternal Latent Mycobacterium tuberculosis Does Not Affect the Infant Immune Response Following BCG at Birth: An Observational Longitudinal Study in Uganda. FRONTIERS IN IMMUNOLOGY, 11. 929-. ISSN 1664-3224 DOI: https://doi.org/10.3389/fimmu.2020.00929
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McCreesh, N; Grant, AD; Yates, TA; Karat, AS; White, RG; (2020) Tuberculosis from transmission in clinics in high HIV settings may be far higher than contact data suggest. International Journal of Tuberculosis and Lung Disease, 24 (4). pp. 403-408. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.19.0410
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McQuaid, C Finn; McCreesh, Nicky; Read, Jonathan M; Sumner, Tom; CMMID COVID-19 Working Group; Houben, Rein MGJ; White, Richard G; Harris, Rebecca C; (2020) The potential impact of COVID-19-related disruption on tuberculosis burden. The European respiratory journal, 56 (2). p. 2001718. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01718-2020
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Mutua, Agnes M; Mogire, Reagan M; Elliott, Alison M; Williams, Thomas N; Webb, Emily L; Abubakar, Amina; Atkinson, Sarah H; (2020) Effects of vitamin D deficiency on neurobehavioural outcomes in children: a systematic review. Wellcome open research, 5. 28-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.15730.2
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Mzembe, Themba; Lessells, Richard; Karat, Aaron S; Randera-Rees, Safiyya; Edwards, Anita; Khan, Palwasha; Tomita, Andrew; Tanser, Frank; Baisley, Kathy; Grant, Alison D; (2020) Prevalence and Risk Factors for Mycobacterium tuberculosis Infection Among Adolescents in Rural South Africa. Open Forum Infectious Diseases, 8 (1). ofaa520-. DOI: https://doi.org/10.1093/ofid/ofaa520 Item availability may be restricted.
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Naker, Kush; Gaskell, Katherine M; Dorjravdan, Munhjargal; Dambaa, Naranzul; Roberts, Chrissy H; Moore, David AJ; (2020) An e-registry for household contacts exposed to multidrug resistant TB in Mongolia. BMC medical informatics and decision making, 20 (1). 188-. ISSN 1472-6947 DOI: https://doi.org/10.1186/s12911-020-01204-z
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Nalugwa, Talemwa; Shete, Priya B; Nantale, Mariam; Farr, Katherine; Ojok, Christopher; Ochom, Emma; Mugabe, Frank; Joloba, Moses; Dowdy, David W; Moore, David AJ; +3 more... Davis, J Lucian; Cattamanchi, Adithya; Katamba, Achilles; (2020) Challenges with scale-up of GeneXpert MTB/RIF® in Uganda: a health systems perspective. BMC HEALTH SERVICES RESEARCH, 20 (1). 162-. DOI: https://doi.org/10.1186/s12913-020-4997-x
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Nimmo, Camus; Brien, Kayleen; Millard, James; Grant, Alison D; Padayatchi, Nesri; Pym, Alexander S; O'Donnell, Max; Goldstein, Richard; Breuer, Judith; Balloux, François; (2020) Dynamics of within-host Mycobacterium tuberculosis diversity and heteroresistance during treatment. EBioMedicine, 55. 102747-. ISSN 2352-3964 DOI: https://doi.org/10.1016/j.ebiom.2020.102747
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Nimmo, Camus; Millard, James; Brien, Kayleen; Moodley, Sashen; van Dorp, Lucy; Lutchminarain, Keeren; Wolf, Allison; Grant, Alison D; Balloux, Francois; Pym, Alexander S; +2 more... Padayatchi, Nesri; O'Donnell, Max; (2020) Bedaquiline resistance in drug-resistant tuberculosis HIV co-infected patients. European Respiratory Journal, 55 (6). p. 1902383. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.02383-2019
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Nimmo, Camus; Millard, James; van Dorp, Lucy; Brien, Kayleen; Moodley, Sashen; Wolf, Allison; Grant, Alison D; Padayatchi, Nesri; Pym, Alexander S; Balloux, François; +1 more... O'Donnell, Max; (2020) Population-level emergence of bedaquiline and clofazimine resistance-associated variants among patients with drug-resistant tuberculosis in southern Africa: a phenotypic and phylogenetic analysis. The Lancet. Microbe, 1 (4). e165-e174. ISSN 2666-5247 DOI: https://doi.org/10.1016/S2666-5247(20)30031-8
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Owolabi, Olumuyiwa A; Jallow, Alpha O; Jallow, Momodou; Sowe, Gambia; Jallow, Rohey; Genekah, Monica D; Donkor, Simon; Wurrie, Alieu; Kampmann, Beate; Sutherland, Jayne; +1 more... Togun, Toyin; (2020) Delay in the diagnosis of pulmonary tuberculosis in The Gambia, West Africa: A cross-sectional study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 101. pp. 102-106. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2020.09.029
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Parwati, CG; Farid, MN; Nasution, HS; Basri, C; Lolong, D; Gebhard, A; Tiemersma, EW; Pambudi, I; Surya, A; Houben, RMGJ; (2020) Estimation of subnational tuberculosis burden: generation and application of a new tool in Indonesia. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 24 (2). pp. 250-257. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.19.0139
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Penn-Nicholson, Adam; Mbandi, Stanley Kimbung; Thompson, Ethan; Mendelsohn, Simon C; Suliman, Sara; Chegou, Novel N; Malherbe, Stephanus T; Darboe, Fatoumatta; Erasmus, Mzwandile; Hanekom, Willem A; +27 more... Bilek, Nicole; Fisher, Michelle; Kaufmann, Stefan HE; Winter, Jill; Murphy, Melissa; Wood, Robin; Morrow, Carl; Van Rhijn, Ildiko; Moody, Branch; Murray, Megan; Andrade, Bruno B; Sterling, Timothy R; Sutherland, Jayne; Naidoo, Kogieleum; Padayatchi, Nesri; Walzl, Gerhard; Hatherill, Mark; Zak, Daniel; Scriba, Thomas J; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team; (2020) RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. Scientific reports, 10 (1). 8629-. DOI: https://doi.org/10.1038/s41598-020-65043-8
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Quaife, Matthew; Houben, Rein MGJ; Allwood, Brian; Cohen, Ted; Coussens, Anna K; Harries, Anthony D; van Kampen, Sanne; Marx, Florian M; Sweeney, Sedona; Wallis, Robert S; +1 more... Menzies, Nicolas A; (2020) Post-tuberculosis mortality and morbidity: valuing the hidden epidemic. The Lancet Respiratory Medicine, 8 (4). pp. 332-333. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(20)30039-4
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Reza, Tania F; Nalugwa, Talemwa; Farr, Katherine; Nantale, Mariam; Oyuku, Denis; Nakaweesa, Annet; Musinguzi, Johnson; Vangala, Moksha; Shete, Priya B; Tucker, Austin; +10 more... Ferguson, Olivia; Fielding, Katherine; Sohn, Hojoon; Dowdy, David; Moore, David AJ; Davis, J Lucian; Ackerman, Sara L; Handley, Margaret A; Katamba, Achilles; Cattamanchi, Adithya; (2020) Study protocol: a cluster randomized trial to evaluate the effectiveness and implementation of onsite GeneXpert testing at community health centers in Uganda (XPEL-TB). Implementation science : IS, 15 (1). 24-. ISSN 1748-5908 DOI: https://doi.org/10.1186/s13012-020-00988-y
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Shuaib, Yassir A; Khalil, Eltahir AG; Wieler, Lothar H; Schaible, Ulrich E; Bakheit, Mohammed A; Mohamed-Noor, Saad E; Abdalla, Mohamed A; Kerubo, Glennah; Andres, Sönke; Hillemann, Doris; +4 more... Richter, Elvira; Kranzer, Katharina; Niemann, Stefan; Merker, Matthias; (2020) Mycobacterium tuberculosis Complex Lineage 3 as Causative Agent of Pulmonary Tuberculosis, Eastern Sudan1. Emerg Infect Dis, 26 (3). pp. 427-436. ISSN 1080-6040 DOI: https://doi.org/10.3201/eid2603.191145
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Tlali, Mpho; Fielding, Katherine L; Karat, Aaron S; Hoffmann, Christopher J; Muravha, Tshifhiwa; Grant, Alison D; Charalambous, Salome; (2020) Sensitivity of the lateral flow urine lipoarabinomannan assay in ambulant adults with advanced HIV disease: data from the TB Fast Track study. Transactions of the Royal Society of Tropical Medicine and Hygiene, 114 (8). pp. 556-560. ISSN 0035-9203 DOI: https://doi.org/10.1093/trstmh/traa018
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Togun, Toyin; Hoggart, Clive J; Agbla, Schadrac C; Gomez, Marie P; Egere, Uzochukwu; Sillah, Abdou K; Saidy, Binta; Mendy, Francis; Pai, Madhukar; Kampmann, Beate; (2020) A three-marker protein biosignature distinguishes tuberculosis from other respiratory diseases in Gambian children. EBioMedicine, 58. 102909-. DOI: https://doi.org/10.1016/j.ebiom.2020.102909
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Togun, Toyin; Kampmann, Beate; Stoker, Neil Graham; Lipman, Marc; (2020) Anticipating the impact of the COVID-19 pandemic on TB patients and TB control programmes. Annals of clinical microbiology and antimicrobials, 19 (1). 21-. DOI: https://doi.org/10.1186/s12941-020-00363-1
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Vickers, Molly A; Darboe, Fatoumatta; Muefong, Caleb N; Mbayo, Georgetta; Barry, Amadou; Gindeh, Awa; Njie, Sainabou; Riley, Abi-Janet; Sarr, Binta; Sambou, Basil; +6 more... Dockrell, Hazel M; Charalambous, Salome; Rachow, Andrea; Owolabi, Olumuyiwa; Jayasooriya, Shamanthi; Sutherland, Jayne S; (2020) Monitoring Anti-tuberculosis Treatment Response Using Analysis of Whole Blood Mycobacterium tuberculosis Specific T Cell Activation and Functional Markers. FRONTIERS IN IMMUNOLOGY, 11. 572620-. ISSN 1664-3224 DOI: https://doi.org/10.3389/fimmu.2020.572620
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Wilson, Daniel J; CRyPTIC Consortium; (2020) GenomegaMap: Within-Species Genome-Wide dN/dS Estimation from over 10,000 Genomes. Molecular biology and evolution, 37 (8). pp. 2450-2460. ISSN 0737-4038 DOI: https://doi.org/10.1093/molbev/msaa069
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van Loon, W; Gomez, MP; Jobe, D; Franken, KLMC; Ottenhoff, THM; Coninx, M; Kestens, L; Sutherland, JS; Kampmann, B; Tientcheu, LD; (2020) Use of resuscitation promoting factors to screen for tuberculosis infection in household-exposed children in The Gambia. BMC infectious diseases, 20 (1). 469-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-020-05194-1
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This list was generated on Mon Jan 30 06:25:40 2023 GMT.