Georgiadis, Markos-Orestis; Kourbeli, Violeta; Ioannidou, Vaya; Karakitsios, Evangelos; Papanastasiou, Ioannis; Tsotinis, Andrew; Komiotis, Dimitri; Vocat, Anthony; Cole, Stewart T; Taylor, Martin C; +1 more... Kelly, John M; (2019) Synthesis of diphenoxyadamantane alkylamines with pharmacological interest. Bioorganic & medicinal chemistry letters, 29 (11). pp. 1278-1281. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2019.04.010 Item availability may be restricted.

Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; +5 more... Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2018) Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines. Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.11.039

Tsagris, DJ; Birchall, K; Bouloc, N; Large, JM; Merritt, A; Smiljanic-Hurley, E; Wheldon, M; Ansell, KH; Kettleborough, C; Whalley, D; +4 more... Stewart, LB; Bowyer, PW; Baker, DA; Osborne, SA; (2018) Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG). Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.08.028 Item availability may be restricted.

Giovani, S; Penzo, M; Brogi, S; Brindisi, M; Gemma, S; Novellino, E; Savini, L; Blackman, MJ; Campiani, G; Butini, S; (2014) Rational design of the first difluorostatone-based PfSUB1 inhibitors. Bioorganic & medicinal chemistry letters, 24 (15). pp. 3582-6. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.05.044 Full text not available from this repository.

Kher, SS; Penzo, M; Fulle, S; Finn, PW; Blackman, MJ; Jirgensons, A; (2014) Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1. Bioorganic & medicinal chemistry letters. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.07.086

Sola, I; Artigas, A; Taylor, MC; Gbedema, SY; Pérez, B; Clos, MV; Wright, CW; Kelly, JM; Muñoz-Torrero, D; (2014) Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines. Bioorganic & medicinal chemistry letters, 24 (23). pp. 5435-5438. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2014.10.025 Full text not available from this repository.

Dellai, A; Appel, J; Bouraoui, A; Croft, S; Nefzi, A; (2013) Antimalarial and cytotoxic activities of chiral triamines. Bioorganic & medicinal chemistry letters, 23 (16). pp. 4579-4582. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2013.06.035 Full text not available from this repository.

Gemma, S; Giovani, S; Brindisi, M; Tripaldi, P; Brogi, S; Savini, L; Fiorini, I; Novellino, E; Butini, S; Campiani, G; +2 more... Penzo, M; Blackman, MJ; (2012) Quinolylhydrazones as novel inhibitors of Plasmodium falciparum serine protease PfSUB1. Bioorganic & medicinal chemistry letters, 22 (16). pp. 5317-21. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.023 Full text not available from this repository.

Kelly, JM; Taylor, MC; Horn, D; Loza, E; Kalvinsh, I; Björkling, F; (2012) Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei. Bioorganic & medicinal chemistry letters, 22 (5). pp. 1886-90. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.01.072

McIver, EG; Bryans, J; Birchall, K; Chugh, J; Drake, T; Lewis, SJ; Osborne, J; Smiljanic-Hurley, E; Tsang, W; Kamal, A; +6 more... Levy, A; Newman, M; Taylor, D; Arthur, JS; Clark, K; Cohen, P; (2012) Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKε kinases. Bioorganic & medicinal chemistry letters, 22 (23). pp. 7169-73. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.09.063 Full text not available from this repository.

Peña, S; Scarone, L; Manta, E; Stewart, L; Yardley, V; Croft, S; Serra, G; (2012) Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. Bioorganic & medicinal chemistry letters, 22 (15). pp. 4994-7. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.028 Full text not available from this repository.

Singh, P; Sachdeva, S; Raj, R; Kumar, V; Mahajan, MP; Nasser, S; Vivas, L; Gut, J; Rosenthal, PJ; Feng, TS; +1 more... Chibale, K; (2011) Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives. Bioorganic & medicinal chemistry letters, 21 (15). pp. 4561-4563. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2011.05.119 Full text not available from this repository.

Thompson, MJ; Louth, JC; Little, SM; Chen, BN; Coldham, I; (2011) 2,4-Diarylthiazole antiprion compounds as a novel structural class of antimalarial leads. Bioorganic & medicinal chemistry letters, 21 (12). pp. 3644-3647. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2011.04.090 Full text not available from this repository.

Blackie, MAL; Yardley, V; Chibale, K; (2010) Synthesis and evaluation of phenylequine for antimalarial activity in vitro and in vivo. Bioorganic & medicinal chemistry letters, 20 (3). pp. 1078-1080. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2009.12.030 Full text not available from this repository.

Dong, YX; Chollet, J; Vargas, M; Mansour, NR; Bickle, Q; Alnouti, Y; Huang, JG; Keiser, J; Vennerstrom, JL; (2010) Praziquantel analogs with activity against juvenile Schistosoma mansoni. Bioorganic & medicinal chemistry letters, 20 (8). pp. 2481-2484. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2010.03.001 Full text not available from this repository.

Mahajan, A; Kumar, V; Mansour, NRN; Bickle, Q; Chibale, K; (2008) Meclonazepam analogues as potential new antihelmintic agents. Bioorganic & medicinal chemistry letters, 18 (7). pp. 2333-2336. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2008.02.077 Full text not available from this repository.

Gernma, S; Kukreja, G; Campiani, G; Butini, S; Bernetti, M; Joshi, BP; Savini, L; Basifico, N; Taramelli, D; Yardley, V; +5 more... Bertamino, A; Novellino, E; Persico, M; Catalanotti, B; Fattorusso, C; (2007) Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistan P-falciparum strains. Synthesis and molecular modeling. Bioorganic & medicinal chemistry letters, 17 (13). pp. 3535-3539. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2007.04.077 Full text not available from this repository.

Khrizman, A; Moulthrop, JS; Little, S; Wharton, H; Yardley, V; Moyna, G; (2007) Synthesis and in vitro protozoocidal activity of diazabicyclic benzotropolone derivatives. Bioorganic & medicinal chemistry letters, 17 (15). pp. 4183-4186. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2007.05.044 Full text not available from this repository.

Kolocouris, N; Zoidis, G; Foscolos, GB; Fytas, G; Prathalingham, SR; Kelly, JM; Naesens, L; De Clercq, E; (2007) Design and synthesis of bioactive adamantane spiro heterocycles. Bioorganic & medicinal chemistry letters, 17 (15). pp. 4358-62. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2007.04.108 Full text not available from this repository.

Musonda, CC; Little, S; Yardley, V; Chibale, K; (2007) Application of multicomponent reactions to antimalarial drug discovery. Part 3: Discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro. Bioorganic & medicinal chemistry letters, 17 (17). pp. 4733-4736. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2007.06.070 Full text not available from this repository.

Coro, J; Atherton, R; Little, S; Wharton, H; Yardley, V; Alvarez, A; Suarez, M; Perez, R; Rodriguez, H; (2006) Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents. Bioorganic & medicinal chemistry letters, 16 (5). pp. 1312-1315. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2005.11.060 Full text not available from this repository.

Gemma, S; Kukreja, G; Fattorusso, C; Persico, M; Romano, MP; Altarelli, M; Savini, L; Campiani, G; Fattorusso, E; Basilico, N; +3 more... Taramelli, D; Yardley, V; Butini, S; (2006) Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains. Bioorganic & medicinal chemistry letters, 16 (20). pp. 5384-8. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2006.07.060 Full text not available from this repository.

Gokhale, NH; Shirisha, K; Padhye, SB; Croft, SL; Kendrick, HD; McKee, V; (2006) Metalloantimalarials: Synthesis, X-ray crystal structure of potent antimalarial copper (II) complex of arylazo-4-hydroxy-1,2-naphthoquinone. Bioorganic & medicinal chemistry letters, 16 (2). pp. 430-432. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2005.09.061 Full text not available from this repository.

Jung, M; Lee, K; Jung, H; Kendrick, H; Yardley, V; Croft, SL; (2004) Antimalarial activities of (+)-deoxoartemisitene and its novel C-11, 13 derivatives. Bioorganic & medicinal chemistry letters, 14 (8). p. 2001. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2003.12.104 Full text not available from this repository.

Bal, G; van der Veken, P; Antonov, D; Lambeir, AM; Grellier, P; Croft, SL; Augustyns, K; Haemers, A; (2003) Prolylisoxazoles: Potent inhibitors of prolyloligopeptidase with antitrypanosomal activity. Bioorganic & medicinal chemistry letters, 13 (17). pp. 2875-2878. ISSN 0960-894X DOI: https://doi.org/10.1016/s0960-894x(03)00579-1 Full text not available from this repository.

Chibale, K; Haupt, H; Kendrick, H; Yardley, V; Saravanamuthu, A; Fairlamb, AH; Croft, SL; (2001) Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorganic & medicinal chemistry letters, 11 (19). pp. 2655-2657. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00528-5 Full text not available from this repository.

Murray, PJ; Kranz, M; Ladlow, M; Taylor, S; Berst, F; Holmes, AB; Keavey, KN; Jaxa-Chamiec, A; Seale, PW; Stead, P; +4 more... Upton, RJ; Croft, SL; Clegg, W; Elsegood, MRJ; (2001) The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin. Bioorganic & medicinal chemistry letters, 11 (6). pp. 773-776. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00049-X Full text not available from this repository.

Ohkanda, J; Lockman, JW; Yokoyama, K; Gelb, MH; Croft, SL; Kendrick, H; Harrell, MI; Feagin, JE; Blaskovich, MA; Sebti, SM; +1 more... Hamilton, AD; (2001) Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity. Bioorganic & medicinal chemistry letters, 11 (6). pp. 761-764. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00055-5 Full text not available from this repository.

Ren, HY; Grady, S; Gamenara, D; Heinzen, H; Moyna, P; Croft, SL; Kendrick, H; Yardley, V; Moyna, G; (2001) Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds. Bioorganic & medicinal chemistry letters, 11 (14). pp. 1851-1854. ISSN 0960-894X DOI: https://doi.org/10.1016/S0960-894X(01)00308-0 Full text not available from this repository.