Browse by Uncontrolled Keywords
Number of items: 24.
2009
Cogen, AL;
Yamasaki, K;
Sanchez, KM;
Dorschner, RA;
Lai, Y;
MacLeod, DT;
Torpey, JW;
Otto, M;
Nizet, V;
Kim, JE;
+1 more...
Gallo, RL;
(2009)
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin.
The Journal of investigative dermatology, 130 (1).
pp. 192-200.
ISSN 0022-202X
DOI: https://doi.org/10.1038/jid.2009.243
Full text not available from this repository.
2008
Musonda, CC;
Yardley, V;
de Souza, RCC;
Ncokazi, K;
Egan, TJ;
Chibale, K;
(2008)
Antiplasmodial, beta-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines.
Organic & biomolecular chemistry, 6 (23).
pp. 4446-4451.
ISSN 1477-0520
DOI: https://doi.org/10.1039/b813007h
Full text not available from this repository.
2007
Blackie, MAL;
Beagley, P;
Croft, SL;
Kendrick, H;
Moss, JR;
Chibale, K;
(2007)
Metallocene-based antimalarials: An exploration into the influence of the ferrocenyl moiety on in vitro antimalarial activity in chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.
Bioorganic & medicinal chemistry, 15 (20).
pp. 6510-6516.
ISSN 0968-0896
DOI: https://doi.org/10.1016/j.bmc.2007.07.012
Full text not available from this repository.
Khrizman, A;
Moulthrop, JS;
Little, S;
Wharton, H;
Yardley, V;
Moyna, G;
(2007)
Synthesis and in vitro protozoocidal activity of diazabicyclic benzotropolone derivatives.
Bioorganic & medicinal chemistry letters, 17 (15).
pp. 4183-4186.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2007.05.044
Full text not available from this repository.
Musonda, CC;
Little, S;
Yardley, V;
Chibale, K;
(2007)
Application of multicomponent reactions to antimalarial drug discovery. Part 3: Discovery of aminoxazole 4-aminoquinolines with potent antiplasmodial activity in vitro.
Bioorganic & medicinal chemistry letters, 17 (17).
pp. 4733-4736.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2007.06.070
Full text not available from this repository.
Too, K;
Brown, DM;
Bongard, E;
Yardley, V;
Vivas, L;
Loakes, D;
(2007)
Anti-malarial activity of N-6-modified purine analogues.
Bioorganic & medicinal chemistry, 15 (16).
pp. 5551-5562.
ISSN 0968-0896
DOI: https://doi.org/10.1016/j.bmc.2007.05.038
Full text not available from this repository.
van Wyk, AWW;
Lobb, KA;
Caira, MR;
Hoppe, HC;
Davies-Coleman, MT;
(2007)
Transformations of Manool. Tri- and Tetracyclic Norditerpenoids with in Vitro Activity against Plasmodium falciparum.
Journal of natural products, 70 (8).
pp. 1253-1258.
ISSN 0163-3864
DOI: https://doi.org/10.1021/np0701071
Full text not available from this repository.
2006
Hudock, MP;
Sanz-Rodriguez, CE;
Song, YC;
Chan, JMW;
Zhang, YH;
Odeh, S;
Kosztowski, T;
Leon-Rossell, A;
Concepcion, JL;
Yardley, V;
+3 more...
Croft, SL;
Urbina, JA;
Oldfield, E;
(2006)
Inhibition of Trypanosoma cruzi hexokinase by bisphosphonates.
Journal of medicinal chemistry, 49 (1).
pp. 215-223.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm0582625
Full text not available from this repository.
2005
Lorente, SO;
Jimenez, CJ;
Gros, L;
Yardley, V;
de Luca-Fradley, K;
Croft, SL;
Urbina, JA;
Ruiz-Perez, LM;
Pacanowska, DG;
Gilbert, IH;
(2005)
Preparation of transition-state analogues of sterol 24-methyl transferase as potential anti-parasities.
Bioorganic & medicinal chemistry, 13 (18).
pp. 5435-5453.
ISSN 0968-0896
DOI: https://doi.org/10.1016/j.bmc.2005.06.012
Full text not available from this repository.
2004
Bhakoo, A;
Raynes, JG;
Heal, JR;
Keller, M;
Miller, AD;
(2004)
De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18).
Molecular immunology, 41 (12).
pp. 1217-1224.
ISSN 0161-5890
DOI: https://doi.org/10.1016/j.molimm.2004.05.011
Full text not available from this repository.
Ghosh, S;
Chan, JMW;
Lea, CR;
Meints, GA;
Lewis, JC;
Tovian, ZS;
Flessner, RM;
Loftus, TC;
Bruchhaus, I;
Kendrick, H;
+5 more...
Croft, SL;
Kemp, RG;
Kobayashi, S;
Nozaki, T;
Oldfield, E;
(2004)
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
Journal of medicinal chemistry, 47 (1).
pp. 175-187.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030084x
Full text not available from this repository.
Mantyla, A;
Garnier, T;
Rautio, R;
Nevalainen, T;
Vepsalainen, J;
Koskinen, A;
Croft, SL;
Jarvinen, T;
(2004)
Synthesis, in vitro evaluation, and antileishmanial activity of water-soluble prodrugs of buparvaquone.
Journal of medicinal chemistry, 47 (1).
pp. 188-195.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm030868a
Full text not available from this repository.
2003
Chauviere, G;
Bouteille, B;
Enanga, B;
de Albuquerque, C;
Croft, SL;
Dumas, M;
Perie, J;
(2003)
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead.
Journal of medicinal chemistry, 46 (3).
pp. 427-440.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm021030a
Full text not available from this repository.
Magaraci, F;
Jimenez, CJ;
Rodrigues, C;
Rodrigues, JCF;
Braga, MV;
Yardley, V;
de Luca-Fradley, K;
Croft, SL;
de Souza, W;
Ruiz-Perez, LM;
+3 more...
Urbina, J;
Pacanowska, DG;
Gilbert, IH;
(2003)
Azasterols as inhibitors of sterol 24-methyltransferase in leishmania species and Trypanosoma cruzi.
Journal of medicinal chemistry, 46 (22).
pp. 4714-4727.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm021114j
Full text not available from this repository.
2002
Jiang, S;
Borthwick, NJ;
Morrison, P;
Gao, GF;
Steward, MW;
(2002)
Virus-specific CTL responses induced by an H-2K(d)-restricted, motif-negative 15-mer peptide from the fusion protein of respiratory syncytial virus.
The Journal of general virology, 83 (Pt 2).
pp. 429-38.
ISSN 0022-1317
https://researchonline.lshtm.ac.uk/id/eprint/17357
Full text not available from this repository.
Jung, MK;
Lee, K;
Kendrick, H;
Robinson, BL;
Croft, SL;
(2002)
Synthesis, stability, and antimalarial activity of new hydrolytically stable and water-soluble (+)-deoxoartelinic acid.
Journal of medicinal chemistry, 45 (22).
pp. 4940-4.
ISSN 0022-2623
DOI: https://doi.org/10.1021/jm020244p
Full text not available from this repository.
2001
Chibale, K;
Haupt, H;
Kendrick, H;
Yardley, V;
Saravanamuthu, A;
Fairlamb, AH;
Croft, SL;
(2001)
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.
Bioorganic & medicinal chemistry letters, 11 (19).
pp. 2655-2657.
ISSN 0960-894X
DOI: https://doi.org/10.1016/S0960-894X(01)00528-5
Full text not available from this repository.
Daunes, S;
D'Silva, C;
Kendrick, H;
Yardley, V;
Croft, SL;
(2001)
QSAR study on the contribution of log P and E-s to the in vitro antiprotozoal activity of glutathione derivatives.
Journal of medicinal chemistry, 44 (18).
pp. 2976-83.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16567
Full text not available from this repository.
Murray, PJ;
Kranz, M;
Ladlow, M;
Taylor, S;
Berst, F;
Holmes, AB;
Keavey, KN;
Jaxa-Chamiec, A;
Seale, PW;
Stead, P;
+4 more...
Upton, RJ;
Croft, SL;
Clegg, W;
Elsegood, MRJ;
(2001)
The synthesis of cyclic tetrapeptoid analogues of the antiprotozoal natural product apicidin.
Bioorganic & medicinal chemistry letters, 11 (6).
pp. 773-776.
ISSN 0960-894X
DOI: https://doi.org/10.1016/S0960-894X(01)00049-X
Full text not available from this repository.
Ohkanda, J;
Lockman, JW;
Yokoyama, K;
Gelb, MH;
Croft, SL;
Kendrick, H;
Harrell, MI;
Feagin, JE;
Blaskovich, MA;
Sebti, SM;
+1 more...
Hamilton, AD;
(2001)
Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity.
Bioorganic & medicinal chemistry letters, 11 (6).
pp. 761-764.
ISSN 0960-894X
DOI: https://doi.org/10.1016/S0960-894X(01)00055-5
Full text not available from this repository.
Ren, HY;
Grady, S;
Gamenara, D;
Heinzen, H;
Moyna, P;
Croft, SL;
Kendrick, H;
Yardley, V;
Moyna, G;
(2001)
Design, synthesis, and biological evaluation of a series of simple and novel potential antimalarial compounds.
Bioorganic & medicinal chemistry letters, 11 (14).
pp. 1851-1854.
ISSN 0960-894X
DOI: https://doi.org/10.1016/S0960-894X(01)00308-0
Full text not available from this repository.
Salmon-Chemin, L;
Buisine, E;
Yardley, V;
Kohler, S;
Debreu, MA;
Landry, V;
Sergheraert, C;
Croft, SL;
Krauth-Siegel, RL;
Davioud-Charvet, E;
(2001)
2-and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: Synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Journal of medicinal chemistry, 44 (4).
pp. 548-65.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16559
Full text not available from this repository.
Wright, CW;
Addae-Kyereme, J;
Breen, AG;
Brown, JE;
Cox, MF;
Croft, SL;
Gokcek, Y;
Kendrick, H;
Phillips, RM;
Pollet, PL;
(2001)
Synthesis and evaluation of cryptolepine analogues for their potential as new antimalarial agents.
Journal of medicinal chemistry, 44 (19).
pp. 3187-94.
ISSN 0022-2623
https://researchonline.lshtm.ac.uk/id/eprint/16568
Full text not available from this repository.
Wyrsta, MD;
Cogen, AL;
Deming, TJ;
(2001)
A parallel synthetic approach for the analysis of membrane interactive copolypeptides.
Journal of the American Chemical Society, 123 (51).
pp. 12919-20.
ISSN 0002-7863
DOI: https://doi.org/10.1021/ja017307y
Full text not available from this repository.