Janssen, Ricky; Engel, Nora; Pant Pai, Nitika; Esmail, Aliasgar; Dheda, Keertan; Thomas, Réjean; Krumeich, Anja; (2021) 'You're only there on the phone'? A qualitative exploration of community, affect and agential capacity in HIV self-testing using a smartphone app. Sociology of health & illness. ISSN 0141-9889 DOI: https://doi.org/10.1111/1467-9566.13242

Kohli, Mikashmi; Schiller, Ian; Dendukuri, Nandini; Yao, Mandy; Dheda, Keertan; Denkinger, Claudia M; Schumacher, Samuel G; Steingart, Karen R; (2021) Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults. The Cochrane database of systematic reviews, 1 (1). CD012768-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD012768.pub3

Metcalfe, John; Bacchetti, Peter; Esmail, Ali; Reckers, Andrew; Aguilar, David; Wen, Anita; Huo, Shu; Muyindike, Winnie R; Hahn, Judith A; Dheda, Keertan; +2 more... Gandhi, Monica; Gerona, Roy; (2021) Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting. BMC infectious diseases, 21 (1). p. 99. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-020-05738-5

Calligaro, Gregory L; Lalla, Usha; Audley, Gordon; Gina, Phindile; Miller, Malcolm G; Mendelson, Marc; Dlamini, Sipho; Wasserman, Sean; Meintjes, Graeme; Peter, Jonathan; +13 more... Levin, Dion; Dave, Joel A; Ntusi, Ntobeko; Meier, Stuart; Little, Francesca; Moodley, Desiree L; Louw, Elizabeth H; Nortje, Andre; Parker, Arifa; Taljaard, Jantjie J; Allwood, Brian W; Dheda, Keertan; Koegelenberg, Coenraad FN; (2020) The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: A multi-centre prospective observational study. EClinicalMedicine, 28. p. 100570. ISSN 2589-5370 DOI: https://doi.org/10.1016/j.eclinm.2020.100570

Dheda, Keertan; Davids, Malika; (2020) LTBI-associated Immuno-diagnostic Test Responses (Standardized IGRAs and the TST) as Biomarkers of Incipient TB: Fruitful or Futile? American journal of respiratory and critical care medicine, 201 (8). pp. 895-898. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201912-2425ED

Dheda, Keertan; Makambwa, Edson; Esmail, Aliasgar; (2020) The Great Masquerader: Tuberculosis Presenting as Community-Acquired Pneumonia. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 41 (4). pp. 592-604. ISSN 1069-3424 DOI: https://doi.org/10.1055/s-0040-1710583

Esmail, Aliasgar; Pooran, Anil; Sabur, Natasha F; Fadul, Mohammed; Brar, Mantaj S; Oelofse, Suzette; Tomasicchio, Michele; Dheda, Keertan; (2020) An Optimal Diagnostic Strategy for Tuberculosis in Hospitalized HIV-Infected Patients Using GeneXpert MTB/RIF and Alere Determine TB LAM Ag. JOURNAL OF CLINICAL MICROBIOLOGY, 58 (10). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.01032-20

Ezewudo, Matthew; Borens, Amanda; Chiner-Oms, Álvaro; Miotto, Paolo; Chindelevitch, Leonid; Starks, Angela M; Hanna, Debra; Liwski, Richard; Zignol, Matteo; Gilpin, Christopher; +19 more... Niemann, Stefan; Kohl, Thomas Andreas; Warren, Robin M; Crook, Derrick; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; McNerney, Ruth; Cirillo, Daniela M; Schito, Marco; Rodwell, Timothy C; Posey, James; (2020) Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. Scientific reports, 10 (1). 3531-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-020-58955-y

Klopper, Marisa; Heupink, Tim Hermanus; Hill-Cawthorne, Grant; Streicher, Elizabeth Maria; Dippenaar, Anzaan; de Vos, Margaretha; Abdallah, Abdallah Musa; Limberis, Jason; Merker, Matthias; Burns, Scott; +5 more... Niemann, Stefan; Dheda, Keertan; Posey, James; Pain, Arnab; Warren, Robin Mark; (2020) A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic. BMC medicine, 18 (1). 24-. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-019-1487-2

Mottay, L; Le Roux, J; Perumal, R; Esmail, A; Timm, L; Sivarasu, S; Dheda, K; (2020) KN95 filtering facepiece respirators distributed in South Africa fail safety testing protocols. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. p. 13162. ISSN 0256-9574 DOI: https://doi.org/10.7196/SAMJ.2021.v111i3.15381

Mthiyane, Thuli; Millard, James; Adamson, John; Balakrishna, Yusentha; Connolly, Cathy; Owen, Andrew; Rustomjee, Roxana; Dheda, Keertan; McIlleron, Helen; Pym, Alexander S; (2020) N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-lsoniazid Pharmacokinetics during Antituberculosis Treatment. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64 (4). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02376-49

Mthiyane, Thuli; Millard, James; Adamson, John; Balakrishna, Yusentha; Connolly, Cathy; Owen, Andrew; Rustomjee, Roxana; Dheda, Keertan; McIlleron, Helen; Pym, Alexander S; (2020) N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment. Antimicrobial agents and chemotherapy, 64 (4). e02376-19. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02376-19

Adams, Shahieda; Ehrlich, Rodney; Baatjies, Roslynn; Dendukuri, Nandini; Wang, Zhuoyu; Dheda, Keertan; (2019) Evaluating Latent Tuberculosis Infection Test Performance Using Latent Class Analysis in a TB and HIV Endemic Setting. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 16 (16). p. 2912. ISSN 1661-7827 DOI: https://doi.org/10.3390/ijerph16162912

Adams, Shahieda; Ehrlich, Rodney; Baatjies, Roslynn; Dendukuri, Nandini; Wang, Zhuoyu; Dheda, Keertan; (2019) Predictors of discordant latent tuberculosis infection test results amongst South African health care workers. BMC infectious diseases, 19 (1). 131-. DOI: https://doi.org/10.1186/s12879-019-3745-5

Davids, Malika; Pooran, Anil; Hermann, Clemens; Mottay, Lynelle; Thompson, Fawziyah; Cardenas, Jacob; Gu, Jinghua; Koeuth, Thearith; Meldau, Richard; Limberis, Jason; +8 more... Gina, Phindile; Srivastava, Shashikant; Calder, Bridget; Esmail, Aliasgar; Tomasicchio, Michele; Blackburn, Jonathan; Gumbo, Tawanda; Dheda, Keertan; (2019) A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin. American journal of respiratory and critical care medicine, 201 (10). pp. 1277-1291. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201908-1580OC

Dheda, Keertan; Lenders, Laura; Srivastava, Shashikant; Magombedze, Gesham; Wainwright, Helen; Raj, Prithvi; Bush, Stephen J; Pollara, Gabriele; Steyn, Rachelle; Davids, Malika; +11 more... Pooran, Anil; Pennel, Timothy; Linegar, Anthony; McNerney, Ruth; Moodley, Loven; Pasipanodya, Jotam G; Turner, Carolin T; Noursadeghi, Mahdad; Warren, Robin M; Wakeland, Edward; Gumbo, Tawanda; (2019) Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200 (3). pp. 370-380. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201807-1361OC

Di Tanna, Gian Luca; Khaki, Ali Raza; Theron, Grant; McCarthy, Kerrigan; Cox, Helen; Mupfumi, Lucy; Trajman, Anete; Zijenah, Lynn Sodai; Mason, Peter; Bandason, Tsitsi; +14 more... Durovni, Betina; Bara, Wilbert; Hoelscher, Michael; Clowes, Petra; Mangu, Chacha; Chanda, Duncan; Pym, Alexander; Mwaba, Peter; Cobelens, Frank; Nicol, Mark P; Dheda, Keertan; Churchyard, Gavin; Fielding, Katherine; Metcalfe, John Z; (2019) Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis. LANCET GLOBAL HEALTH, 7 (2). e191-e199. ISSN 2214-109X DOI: https://doi.org/10.1016/S2214-109X(18)30458-3

Gupta-Wright, Ankur; Corbett, Elizabeth L; Wilson, Douglas; van Oosterhout, Joep J; Dheda, Keertan; Huerga, Helena; Peter, Jonny; Bonnet, Maryline; Alufandika-Moyo, Melanie; Grint, Daniel; +2 more... Lawn, Stephen D; Fielding, Katherine; (2019) Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study. PLoS medicine, 16 (4). e1002776-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1002776

Hendricks, Rushdi; Davids, Malika; Khalfey, Hoosain; Landman, Hilda J; Theron, Anne E; Engela, Eugene; Dheda, Keertan; (2019) Sleepiness Score-Specific Outcomes of a Novel Tongue Repositioning Procedure for the Treatment of Continuous Positive Airway Pressure-Resistant Obstructive Sleep Apnea. Annals of Maxillofacial Surgery, 9 (1). pp. 28-36. ISSN 2231-0746 DOI: https://doi.org/10.4103/ams.ams_151_18

Janssen, Ricky; Engel, Nora; Esmail, Aliasgar; Oelofse, Suzette; Krumeich, Anja; Dheda, Keertan; Pai, Nitika Pant; (2019) Alone But Supported: A Qualitative Study of an HIV Self-testing App in an Observational Cohort Study in South Africa. AIDS and Behavior, 24 (2). pp. 467-474. ISSN 1090-7165 DOI: https://doi.org/10.1007/s10461-019-02516-6

Khan, Palwasha Y; Yates, Tom A; Osman, Muhammad; Warren, Robin M; van der Heijden, Yuri; Padayatchi, Nesri; Nardell, Edward A; Moore, David; Mathema, Barun; Gandhi, Neel; +6 more... Eldholm, Vegard; Dheda, Keertan; Hesseling, Anneke C; Mizrahi, Valerie; Rustomjee, Roxana; Pym, Alexander; (2019) Transmission of drug-resistant tuberculosis in HIV-endemic settings. LANCET INFECTIOUS DISEASES, 19 (3). e77-e88. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(18)30537-1

Meldau, Richard; Randall, Philippa; Pooran, Anil; Limberis, Jason; Makambwa, Edson; Dhansay, Muhammed; Esmail, Aliasgar; Dheda, Keertan; (2019) Same-Day Tools, Including Xpert Ultra and IRISA-TB, for Rapid Diagnosis of Pleural Tuberculosis: a Prospective Observational Study. Journal of clinical microbiology, 57 (9). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.00614-19

Metcalfe, John; Bacchetti, Peter; Gerona, Roy; Esmail, Ali; Dheda, Keertan; Gandhi, Monica; (2019) Association of anti-tuberculosis drug concentrations in hair and treatment outcomes in MDR- and XDR-TB. ERJ Open Research, 5 (2). 00046-2019. ISSN 2312-508X DOI: https://doi.org/10.1183/23120541.00046-2019

Olayanju, Olatunde; Esmail, Aliasgar; Limberis, Jason; Dheda, Keertan; (2019) A regimen containing bedaquiline and delamanid compared to bedaquiline in patients with drug-resistant tuberculosis. The European respiratory journal, 55 (1). p. 1901181. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01181-2019

Olayanju, Olatunde; Esmail, Aliasgar; Limberis, Jason; Gina, Phindile; Dheda, Keertan; (2019) Linezolid interruption in patients with fluoroquinolone-resistant tuberculosis receiving a bedaquiline-based treatment regimen. International journal of infectious diseases, 85. pp. 74-79. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2019.04.028

Pooran, Anil; Davids, Malika; Nel, Andrew; Shoko, Aubrey; Blackburn, Jonathan; Dheda, Keertan; (2019) IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages. The European respiratory journal, 54 (2). p. 1802242. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.02242-2018

Pooran, Anil; Theron, Grant; Zijenah, Lynn; Chanda, Duncan; Clowes, Petra; Mwenge, Lawrence; Mutenherwa, Farirai; Lecesse, Paul; Metcalfe, John; Sohn, Hojoon; +5 more... Hoelscher, Michael; Pym, Alex; Peter, Jonny; Dowdy, David; Dheda, Keertan; (2019) Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation. LANCET GLOBAL HEALTH, 7 (6). e798-e807. DOI: https://doi.org/10.1016/S2214-109X(19)30164-0

Sharma, Surendra K; Dheda, Keertan; (2019) What is new in the WHO consolidated guidelines on drug-resistant tuberculosis treatment? INDIAN JOURNAL OF MEDICAL RESEARCH, 149 (3). pp. 309-312. ISSN 0971-5916 DOI: https://doi.org/10.4103/ijmr.IJMR_579_19

Siddiqi, Omar K; Birbeck, Gretchen L; Ghebremichael, Musie; Mubanga, Eugene; Love, Shawn; Buback, Clayton; Kosloff, Barry; Ayles, Helen; Atadzhanov, Masharip; Dheda, Keertan; +1 more... Koralnik, Igor J; (2019) Prospective Cohort Study on Performance of Cerebrospinal Fluid (CSF) Xpert MTB/RIF, CSF Lipoarabinomannan (LAM) Lateral Flow Assay (LFA), and Urine LAM LFA for Diagnosis of Tuberculous Meningitis in Zambia. JOURNAL OF CLINICAL MICROBIOLOGY, 57 (8). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.00652-19

Tadzimirwa, GY; Day, C; Esmail, A; Cooper, C; Kamkuemah, M; Dheda, K; Van Zyl-Smit, RN; (2019) Challenges for dedicated smoking cessation services in developing countries. SAMJ SOUTH AFRICAN MEDICAL JOURNAL, 109 (6). pp. 431-436. ISSN 0256-9574 DOI: https://doi.org/10.7196/SAMJ.2019.v109i6.13631

Tamgue, Ousman; Gcanga, Lorna; Ozturk, Mumin; Whitehead, Lauren; Pillay, Shandre; Jacobs, Raygaana; Roy, Sugata; Schmeier, Sebastian; Davids, Malika; Medvedeva, Yulia A; +4 more... Dheda, Keertan; Suzuki, Harukazu; Brombacher, Frank; Guler, Reto; (2019) Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages. Frontiers in immunology, 10 (MAR). 421-. DOI: https://doi.org/10.3389/fimmu.2019.00421

Tomasicchio, Michele; Semple, Lynn; Esmail, Aliasgar; Meldau, Richard; Randall, Philippa; Pooran, Anil; Davids, Malika; Cairncross, Lydia; Anderson, David; Downs, Jennifer; +7 more... Malherbe, Francois; Novitzky, Nicolas; Panieri, Eugenio; Oelofse, Suzette; Londt, Rolanda; Naiker, Thurandrie; Dheda, Keertan; (2019) An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells. CANCER IMMUNOLOGY IMMUNOTHERAPY, 68 (1). pp. 71-83. ISSN 0340-7004 DOI: https://doi.org/10.1007/s00262-018-2238-5

Wasserman, Sean; Denti, Paolo; Brust, James CM; Abdelwahab, Mahmoud; Hlungulu, Siphokazi; Wiesner, Lubbe; Norman, Jennifer; Sirgel, Frederick A; Warren, Robin M; Esmail, Aliasgar; +4 more... Dheda, Keertan; Gandhi, Neel R; Meintjes, Graeme; Maartens, Gary; (2019) Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection. Antimicrobial agents and chemotherapy, 63 (3). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02164-18

Aggerbeck, Henrik; Ruhwald, Morten; Hoff, Søren T; Borregaard, Bettine; Hellstrom, Elizabeth; Malahleha, Mookho; Siebert, Mirna; Gani, Mashra; Seopela, Vincent; Diacon, Andreas; +3 more... Lourens, Madeleine; Andersen, Peter; Dheda, Keertan; (2018) C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIV-infected adults: A phase 3 trial. PLOS ONE, 13 (9). e0204554-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0204554

Beynon, Fenella; Theron, Grant; Respeito, Durval; Mambuque, Edson; Saavedra, Belen; Bulo, Helder; Sanz, Sergi; Dheda, Keertan; Garcia-Basteiro, Alberto L; (2018) Correlation of Xpert MTB/RIF with measures to assess Mycobacterium tuberculosis bacillary burden in high HIV burden areas of Southern Africa. Scientific reports, 8 (1). 5201-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-23066-2

Coll, Francesc; Phelan, Jody; Hill-Cawthorne, Grant A; Nair, Mridul B; Mallard, Kim; Ali, Shahjahan; Abdallah, Abdallah M; Alghamdi, Saad; Alsomali, Mona; Ahmed, Abdallah O; +41 more... Portelli, Stephanie; Oppong, Yaa; Alves, Adriana; Bessa, Theolis Barbosa; Campino, Susana; Caws, Maxine; Chatterjee, Anirvan; Crampin, Amelia C; Dheda, Keertan; Furnham, Nicholas; Glynn, Judith R; Grandjean, Louis; Minh Ha, Dang; Hasan, Rumina; Hasan, Zahra; Hibberd, Martin L; Joloba, Moses; Jones-López, Edward C; Matsumoto, Tomoshige; Miranda, Anabela; Moore, David J; Mocillo, Nora; Panaiotov, Stefan; Parkhill, Julian; Penha, Carlos; Perdigão, João; Portugal, Isabel; Rchiad, Zineb; Robledo, Jaime; Sheen, Patricia; Shesha, Nashwa Talaat; Sirgel, Frik A; Sola, Christophe; Oliveira Sousa, Erivelton; Streicher, Elizabeth M; Helden, Paul Van; Viveiros, Miguel; Warren, Robert M; McNerney, Ruth; Pain, Arnab; Clark, Taane G; (2018) Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature genetics, 50 (2). pp. 307-316. ISSN 1061-4036 DOI: https://doi.org/10.1038/s41588-017-0029-0

Coll, Francesc; Phelan, Jody; Hill-Cawthorne, Grant A; Nair, Mridul B; Mallard, Kim; Ali, Shahjahan; Abdallah, Abdallah M; Alghamdi, Saad; Alsomali, Mona; Ahmed, Abdallah O; +41 more... Portelli, Stephanie; Oppong, Yaa; Alves, Adriana; Bessa, Theolis Barbosa; Campino, Susana; Caws, Maxine; Chatterjee, Anirvan; Crampin, Amelia C; Dheda, Keertan; Furnham, Nicholas; Glynn, Judith R; Grandjean, Louis; Ha, Dang Minh; Hasan, Rumina; Hasan, Zahra; Hibberd, Martin L; Joloba, Moses; Jones-López, Edward C; Matsumoto, Tomoshige; Miranda, Anabela; Moore, David J; Mocillo, Nora; Panaiotov, Stefan; Parkhill, Julian; Penha, Carlos; Perdigão, João; Portugal, Isabel; Rchiad, Zineb; Robledo, Jaime; Sheen, Patricia; Shesha, Nashwa Talaat; Sirgel, Frik A; Sola, Christophe; Sousa, Erivelton Oliveira; Streicher, Elizabeth M; Van Helden, Paul; Viveiros, Miguel; Warren, Robert M; McNerney, Ruth; Pain, Arnab; Clark, Taane G; (2018) Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature genetics, 50 (5). 764-. ISSN 1061-4036 DOI: https://doi.org/10.1038/s41588-018-0074-3 Full text not available from this repository.

Deshpande, Devyani; Srivastava, Shashikant; Bendet, Paula; Martin, Katherine R; Cirrincione, Kayle N; Lee, Pooi S; Pasipanodya, Jotam G; Dheda, Keertan; Gumbo, Tawanda; (2018) Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62 (2). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02232-17

Ezewudo, Matthew; Borens, Amanda; Chiner-Oms, Álvaro; Miotto, Paolo; Chindelevitch, Leonid; Starks, Angela M; Hanna, Debra; Liwski, Richard; Zignol, Matteo; Gilpin, Christopher; +19 more... Niemann, Stefan; Kohl, Thomas Andreas; Warren, Robin M; Crook, Derrick; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; McNerney, Ruth; Cirillo, Daniela M; Schito, Marco; Rodwell, Timothy C; Posey, James; (2018) Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. SCIENTIFIC REPORTS, 8 (1). 15382-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-33731-1

Kohli, Mikashmi; Schiller, Ian; Dendukuri, Nandini; Dheda, Keertan; Denkinger, Claudia M; Schumacher, Samuel G; Steingart, Karen R; (2018) Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 8 (8). CD012768-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD012768.pub2

Pham, Thu Hang; Peter, Jonathan; Mello, Fernanda CQ; Parraga, Tommy; Lan, Nguyen Thi Ngoc; Nabeta, Pamela; Valli, Eloise; Caceres, Tatiana; Dheda, Keertan; Dorman, Susan E; +3 more... Hillemann, Doris; Gray, Christen M; Perkins, Mark D; (2018) Performance of the TB-LAMP diagnostic assay in reference laboratories: Results from a multicentre study. International journal of infectious diseases, 68. pp. 44-49. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2018.01.005

Seipone, Ikanyeng D; Singh, Ravesh; Patel, Vinod B; Singh, Avashna; Gordon, Michelle L; Muema, Daniel M; Dheda, Keertan; Ndung'u, Thumbi; (2018) Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides. PLOS ONE, 13 (2). e0192060-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0192060

Sharma, Surendra Kumar; Mohan, Alladi; Singh, Achintya Dinesh; Mishra, Hridesh; Jhanjee, Sonali; Pandey, Ravindra Mohan; Singh, Binit Kumar; Sharma, Rohini; Pallipamu, Prakash Babu; Pai, Madhukar; +1 more... Dheda, Keertan; (2018) Impact of nicotine replacement therapy as an adjunct to anti-tuberculosis treatment and behaviour change counselling in newly diagnosed pulmonary tuberculosis patients: an open-label, randomised controlled trial. SCIENTIFIC REPORTS, 8 (1). 8828-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-26990-5

Tomasicchio, Michele; Davids, Malika; Pooran, Anil; Theron, Grant; Smith, Liezel; Semple, Lynn; Meldau, Richard; Hapgood, Janet Patricia; Dheda, Keertan; (2018) The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor. The Journal of infectious diseases, 219 (8). pp. 1329-1337. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiy657

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant; (2017) Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017). BMJ OPEN, 7 (11). e017604-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-017604

Deshpande, Devyani; Srivastava, Shashikant; Chapagain, Moti; Magombedze, Gesham; Martin, Katherine R; Cirrincione, Kayle N; Lee, Pooi S; Koeuth, Thearith; Dheda, Keertan; Gumbo, Tawanda; (2017) Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis. SCIENCE ADVANCES, 3 (8). e1701102-. ISSN 2375-2548 DOI: https://doi.org/10.1126/sciadv.1701102

Dheda, Keertan; Gumbo, Tawanda; Maartens, Gary; Dooley, Kelly E; McNerney, Ruth; Murray, Megan; Furin, Jennifer; Nardell, Edward A; London, Leslie; Lessem, Erica; +32 more... Theron, Grant; van Helden, Paul; Niemann, Stefan; Merker, Matthias; Dowdy, David; Van Rie, Annelies; Siu, Gilman KH; Pasipanodya, Jotam G; Rodrigues, Camilla; Clark, Taane G; Sirgel, Frik A; Esmail, Aliasgar; Lin, Hsien-Ho; Atre, Sachin R; Schaaf, H Simon; Chang, Kwok Chiu; Lange, Christoph; Nahid, Payam; Udwadia, Zarir F; Horsburgh, C Robert; Churchyard, Gavin J; Menzies, Dick; Hesseling, Anneke C; Nuermberger, Eric; McIlleron, Helen; Fennelly, Kevin P; Goemaere, Eric; Jaramillo, Ernesto; Low, Marcus; Jara, Carolina Morán; Padayatchi, Nesri; Warren, Robin M; (2017) The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. The lancet Respiratory medicine, 5 (4). pp. 291-360. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(17)30079-6 Full text not available from this repository.

Dheda, Keertan; Limberis, Jason D; Pietersen, Elize; Phelan, Jody; Esmail, Aliasgar; Lesosky, Maia; Fennelly, Kevin P; Te Riele, Julian; Mastrapa, Barbara; Streicher, Elizabeth M; +13 more... Dolby, Tania; Abdallah, Abdallah M; Ben-Rached, Fathia; Simpson, John; Smith, Liezel; Gumbo, Tawanda; van Helden, Paul; Sirgel, Frederick A; McNerney, Ruth; Theron, Grant; Pain, Arnab; Clark, Taane G; Warren, Robin M; (2017) Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study. The lancet Respiratory medicine, 5 (4). pp. 269-281. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(16)30433-7 Full text not available from this repository.

Dowdy, David W; Grant, Alison D; Dheda, Keertan; Nardell, Edward; Fielding, Katherine; Moore, David AJ; (2017) Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. The Journal of infectious diseases, 216 (suppl_). S654-S661. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jix320

Engel, Nora; Davids, Malika; Blankvoort, Nadine; Dheda, Keertan; Pant Pai, Nitika; Pai, Madhukar; (2017) Making HIV testing work at the point of care in South Africa: a qualitative study of diagnostic practices. BMC HEALTH SERVICES RESEARCH, 17 (1). 408-. ISSN 1472-6963 DOI: https://doi.org/10.1186/s12913-017-2353-6

Gina, Phindile; Randall, Philippa J; Muchinga, Tapuwa E; Pooran, Anil; Meldau, Richard; Peter, Jonny G; Dheda, Keertan; (2017) Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection. BMC INFECTIOUS DISEASES, 17 (1). 339-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-017-2313-0

Lange, B; Khan, P; Kalmambetova, G; Al-Darraji, HA; Alland, D; Antonenka, U; Brown, T; Balcells, ME; Blakemore, R; Denkinger, CM; +14 more... Dheda, K; Hoffmann, H; Kadyrov, A; Lemaitre, N; Miller, MB; Nikolayevskyy, V; Ntinginya, EN; Ozkutuk, N; Palacios, JJ; Popowitch, EB; Porcel, JM; Teo, J; Theron, G; Kranzer, K; (2017) Diagnostic accuracy of the Xpert® MTB/RIF cycle threshold level to predict smear positivity: a meta-analysis. The international journal of tuberculosis and lung disease, 21 (5). pp. 493-502. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.16.0702 Full text not available from this repository.

Miotto, Paolo; Tessema, Belay; Tagliani, Elisa; Chindelevitch, Leonid; Starks, Angela M; Emerson, Claudia; Hanna, Debra; Kim, Peter S; Liwski, Richard; Zignol, Matteo; +25 more... Gilpin, Christopher; Niemann, Stefan; Denkinger, Claudia M; Fleming, Joy; Warren, Robin M; Crook, Derrick; Posey, James; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Murray, Megan; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; Ranganathan, Uma Devi K; McNerney, Ruth; Ezewudo, Matthew; Cirillo, Daniela M; Schito, Marco; Köser, Claudio U; Rodwell, Timothy C; (2017) A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis. EUROPEAN RESPIRATORY JOURNAL, 50 (6). p. 1701354. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01354-2017

Nasejje, Justine B; Mwambi, Henry; Dheda, Keertan; Lesosky, Maia; (2017) A comparison of the conditional inference survival forest model to random survival forests based on a simulation study as well as on two applications with time-to-event data. BMC MEDICAL RESEARCH METHODOLOGY, 17 (1). 115-. ISSN 1471-2288 DOI: https://doi.org/10.1186/s12874-017-0383-8

Sabur, Natasha F; Esmail, Aliasgar; Brar, Mantaj S; Dheda, Keertan; (2017) Diagnosing tuberculosis in hospitalized HIV-infected individuals who cannot produce sputum: is urine lipoarabinomannan testing the answer? BMC INFECTIOUS DISEASES, 17 (1). 803-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-017-2914-7

Furin, J; Alirol, E; Allen, E; Fielding, K; Merle, C; Abubakar, I; Andersen, J; Davies, G; Dheda, K; Diacon, A; +23 more... Dooley, KE; Dravnice, G; Eisenach, K; Everitt, D; Ferstenberg, D; Goolam-Mahomed, A; Grobusch, MP; Gupta, R; Harausz, E; Harrington, M; Horsburgh, CR; Lienhardt, C; McNeeley, D; Mitnick, CD; Nachman, S; Nahid, P; Nunn, AJ; Phillips, P; Rodriguez, C; Shah, S; Wells, C; Thomas-Nyang'wa, B; du Cros, P; (2016) Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults. The international journal of tuberculosis and lung disease, 20 (3). pp. 290-294. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.15.0490 Full text not available from this repository.

Grobler, Liesl; Mehtar, Shaheen; Dheda, Keertan; Adams, Shahieda; Babatunde, Sanni; van der Walt, Martie; Osman, Muhammad; (2016) The epidemiology of tuberculosis in health care workers in South Africa: a systematic review. BMC HEALTH SERVICES RESEARCH, 16 (1). 416-. ISSN 1472-6963 DOI: https://doi.org/10.1186/s12913-016-1601-5

Lehloenya, Rannakoe J; Dlamini, Sipho; Muloiwa, Rudzani; Kakande, Betty; Ngwanya, Mzudumile R; Todd, Gail; Dheda, Keertan; (2016) Therapeutic Trial of Rifabutin After Rifampicin-Associated DRESS Syndrome in Tuberculosis-Human Immunodeficiency Virus Coinfected Patients. OPEN FORUM INFECTIOUS DISEASES, 3 (3). ofw130-. ISSN 2328-8957 DOI: https://doi.org/10.1093/ofid/ofw130

McNerney, Ruth; Clark, Taane G; Campino, Susana; Rodrigues, Camilla; Dolinger, David; Smith, Liezel; Cabibbe, Andrea M; Dheda, Keertan; Schito, Marco; (2016) Removing the bottleneck in whole genome sequencing of Mycobacterium tuberculosis for rapid drug resistance analysis: a call to action. International journal of infectious diseases, 56. pp. 130-135. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2016.11.422

Melendez, Jaime; Sánchez, Clara I; Philipsen, Rick HHM; Maduskar, Pragnya; Dawson, Rodney; Theron, Grant; Dheda, Keertan; van Ginneken, Bram; (2016) An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information. SCIENTIFIC REPORTS, 6 (1). 25265-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep25265

Pandie, Shaheen; Peter, Jonathan G; Kerbelker, Zita S; Meldau, Richard; Theron, Grant; Govender, Ureshnie; Ntsekhe, Mpiko; Dheda, Keertan; Mayosi, Bongani M; (2016) The diagnostic accuracy of pericardial and urinary lipoarabinomannan (LAM) assays in patients with suspected tuberculous pericarditis. SCIENTIFIC REPORTS, 6 (1). 32924-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep32924

Phelan, Jody E; Coll, Francesc; Bergval, Indra; Anthony, Richard M; Warren, Rob; Sampson, Samantha L; Gey van Pittius, Nicolaas C; Glynn, Judith R; Crampin, Amelia C; Alves, Adriana; +20 more... Bessa, Theolis Barbosa; Campino, Susana; Dheda, Keertan; Grandjean, Louis; Hasan, Rumina; Hasan, Zahra; Miranda, Anabela; Moore, David; Panaiotov, Stefan; Perdigao, Joao; Portugal, Isabel; Sheen, Patricia; de Oliveira Sousa, Erivelton; Streicher, Elizabeth M; van Helden, Paul D; Viveiros, Miguel; Hibberd, Martin L; Pain, Arnab; McNerney, Ruth; Clark, Taane G; (2016) Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages. BMC genomics, 17 (1). 151-. ISSN 1471-2164 DOI: https://doi.org/10.1186/s12864-016-2467-y

Phelan, Jody; O'Sullivan, Denise M; Machado, Diana; Ramos, Jorge; Whale, Alexandra S; O'Grady, Justin; Dheda, Keertan; Campino, Susana; McNerney, Ruth; Viveiros, Miguel; +2 more... Huggett, Jim F; Clark, Taane G; (2016) The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs. Genome medicine, 8 (1). 132-. ISSN 1756-994X DOI: https://doi.org/10.1186/s13073-016-0385-x

Senthilingam, Meera; Pietersen, Elize; McNerney, Ruth; Te Riele, Julian; Sedres, Pat; Wilson, Ruth; Dheda, Keertan; (2015) Lifestyle, attitudes and needs of uncured XDR-TB patients living in the communities of South Africa: a qualitative study. Tropical medicine & international health, 20 (9). pp. 1155-1161. ISSN 1360-2276 DOI: https://doi.org/10.1111/tmi.12532 Full text not available from this repository.

Lawn, Stephen D; Dheda, Keertan; Kerkhoff, Andrew D; Peter, Jonathan G; Dorman, Susan; Boehme, Catharina C; Nicol, Mark P; (2013) Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies. BMC infectious diseases, 13 (1). 407-. ISSN 1471-2334 DOI: https://doi.org/10.1186/1471-2334-13-407

Pant Pai, Nitika; Sharma, Jigyasa; Shivkumar, Sushmita; Pillay, Sabrina; Vadnais, Caroline; Joseph, Lawrence; Dheda, Keertan; Peeling, Rosanna W; (2013) Supervised and unsupervised self-testing for HIV in high- and low-risk populations: a systematic review. PLoS medicine, 10 (4). e1001414-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001414

Anandaiah, Asha; Dheda, Keertan; Keane, Joseph; Koziel, Henry; Moore, David AJ; Patel, Naimish R; (2011) Novel developments in the epidemic of human immunodeficiency virus and tuberculosis coinfection. American journal of respiratory and critical care medicine, 183 (8). pp. 987-997. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201008-1246CI Full text not available from this repository.

Tomlinson, Gillian S; Cashmore, Tamaryn J; Elkington, Paul TG; Yates, John; Lehloenya, Rannakoe J; Tsang, Jhen; Brown, Michael; Miller, Robert F; Dheda, Keertan; Katz, David R; +2 more... Chain, Benjamin M; Noursadeghi, Mahdad; (2011) Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test. European journal of immunology, 41 (11). pp. 3253-3260. ISSN 0014-2980 DOI: https://doi.org/10.1002/eji.201141841

Dheda, Keertan; Shean, Karen; Zumla, Alimuddin; Badri, Motasim; Streicher, Elizabeth M; Page-Shipp, Liesl; Willcox, Paul; John, Melanie-Anne; Reubenson, Gary; Govindasamy, Darshini; +13 more... Wong, Michelle; Padanilam, Xavier; Dziwiecki, Alicia; van Helden, Paul D; Siwendu, Sweetness; Jarand, Julie; Menezes, Colin N; Burns, Avril; Victor, Thomas; Warren, Robin; Grobusch, Martin P; van der Walt, Martie; Kvasnovsky, Charlotte; (2010) Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study. Lancet, 375 (9728). pp. 1798-1807. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(10)60492-8

Hanekom, WA; Lawn, SD; Dheda, K; Whitelaw, A; (2010) Tuberculosis research update. Tropical medicine & international health, 15 (8). pp. 981-989. ISSN 1360-2276 DOI: https://doi.org/10.1111/j.1365-3156.2010.02568.x Full text not available from this repository.