Akkerman, OW; Duarte, R; Tiberi, S; Schaaf, HS; Lange, C; Alffenaar, JWC; Denholm, J; Carvalho, ACC; Bolhuis, MS; Borisov, S; +37 more... Bruchfeld, J; Cabibbe, AM; Caminero, JA; Carvalho, I; Chakaya, J; Centis, R; Dalcomo, MP; D Ambrosio, L; Dedicoat, M; Dheda, K; Dooley, KE; Furin, J; García-García, J-M; van Hest, NAH; de Jong, BC; Kurhasani, X; Märtson, AG; Mpagama, S; Torrico, M Munoz; Nunes, E; Ong, CWM; Palmero, DJ; Ruslami, R; Saktiawati, AMI; Semuto, C; Silva, DR; Singla, R; Solovic, I; Srivastava, S; de Steenwinkel, JEM; Story, A; Sturkenboom, MGG; Tadolini, M; Udwadia, ZF; Verhage, AR; Zellweger, JP; Migliori, GB; (2022) Clinical standards for drug-susceptible pulmonary TB. International Journal of Tuberculosis and Lung Disease, 26 (7). pp. 592-604. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.22.0228

Anderson, K; Pietersen, E; Dheda, K; van der Heijden, YF; (2022) Comparison of treatment outcome definitions in drug-resistant tuberculosis patients with high incidence of acquired second-line drug resistance. African Journal of Thoracic and Critical Care Medicine, 28 (2). pp. 59-65. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2022.v28i2.177

Anderson, Kim; Pietersen, Elize; Shepherd, Bryan E; Bian, Aihua; Dheda, Keertan; Warren, Robin; Sterling, Timothy R; van der Heijden, Yuri F; (2022) High mortality among patients hospitalized for drug-resistant tuberculosis with acquired second-line drug resistance and high HIV prevalence. HIV medicine, 23 (10). pp. 1085-1097. ISSN 1464-2662 DOI: https://doi.org/10.1111/hiv.13318

Esmail, A; Scott, AJ; Dheda, K; (2022) Evolution of SARS-CoV-2 mutational variants: Hysteria or hope for the future? African journal of thoracic and critical care medicine, 27 (4). pp. 136-137. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2021.v27i4.204

Koegelenberg, CFN; van Zyl-Smit, RN; Dheda, K; Allwood, BW; Vorster, MJ; Plekker, D; Slebos, D-J; Klooster, K; Shah, PL; Herth, FJF; +1 more... Assembly on Interventional Pulmonology of the South African Thor; (2022) Position statement on endoscopic lung volume reduction in South Africa: 2022 update. African Journal of Thoracic and Critical Care Medicine, 28 (2). pp. 75-81. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2022.v28i2.249

Kühn, L; Esmail, A; Oelofse, S; Dheda, K; (2022) A breath of relief: High-flow nasal oxygen in a resource-limited setting. African journal of thoracic and critical care medicine, 28 (1). pp. 3-4. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2022.v28i1.223

Lalloo, UG; Kalla, IS; Abdool-Gaffar, S; Dheda, K U; Koegelenberg, CFN; Greenblatt, M; Feldman, C; Wong, ML; van Zyl-Smit, RN; (2022) Guidelines for the management of asthma in adults and adolescents: Position statement of the South African Thoracic Society - 2021 update. African journal of thoracic and critical care medicine, 27 (4). pp. 187-199. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2021.v27i4.189

Madhi, Shabir A; Moodley, Dhayendre; Hanley, Sherika; Archary, Moherndran; Hoosain, Zaheer; Lalloo, Umesh; Louw, Cheryl; Fairlie, Lee; Fouche, Leon Frederik; Masilela, Mduduzi SL; +38 more... Singh, Nishanta; Grobbelaar, Coert; Ahmed, Khatija; Benadé, Gabriella; Bhikha, Sutika; Bhorat, As'ad Ebrahim; Bhorat, Qasim; Joseph, Natasha; Dheda, Keertan; Esmail, Aliasgar; Foulkes, Sharne; Goga, Ameena; Oommen Jose, Aylin; Kruger, Gertruida; Kalonji, Dishiki J; Lalloo, Natasha; Lombaard, Johan J; Lombard Koen, Anthonet; Kany Luabeya, Angelique; Mngqibisa, Rosie; Petrick, Friedrich G; Pitsi, Annah; Tameris, Michele; Thombrayil, Asha; Vollgraaff, Pieter-Louis; Cloney-Clark, Shane; Zhu, Mingzhu; Bennett, Chijioke; Albert, Gary; Faust, Emmanuel; Plested, Joyce S; Fries, Lou; Robertson, Andreana; Neal, Susan; Cho, Iksung; Glenn, Greg M; Shinde, Vivek; 2019nCoV-501 Study Group; (2022) Immunogenicity and safety of a SARS-CoV-2 recombinant spike protein nanoparticle vaccine in people living with and without HIV-1 infection: a randomised, controlled, phase 2A/2B trial. The lancet. HIV, 9 (5). e309-e322. ISSN 2405-4704 DOI: https://doi.org/10.1016/S2352-3018(22)00041-8

Oostvogels, Selien; Ley, Serej D; Heupink, Tim H; Dippenaar, Anzaan; Streicher, Elizabeth M; De Vos, Elise; Meehan, Conor J; Dheda, Keertan; Warren, Rob; Van Rie, Annelies; (2022) Transmission, distribution and drug resistance-conferring mutations of extensively drug-resistant tuberculosis in the Western Cape Province, South Africa. Microbial Genomics, 8 (4). ISSN 2057-5858 DOI: https://doi.org/10.1099/mgen.0.000815

Abdelwahab, Mahmoud Tareq; Wasserman, Sean; Brust, James CM; Dheda, Keertan; Wiesner, Lubbe; Gandhi, Neel R; Warren, Robin M; Sirgel, Frederick A; Meintjes, Graeme; Maartens, Gary; +1 more... Denti, Paolo; (2021) Linezolid Population Pharmacokinetics in South African Adults with Drug-Resistant Tuberculosis. Antimicrobial agents and chemotherapy, 65 (12). e0138121-. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01381-21

D'Ambrosio, Lia; Centis, Rosella; Dobler, Claudia C; Tiberi, Simon; Matteelli, Alberto; Denholm, Justin; Zenner, Dominik; Al-Abri, Seif; Alyaquobi, Fatma; Arbex, Marcos Abdo; +26 more... Belilovskiy, Evgeny; Blanc, François-Xavier; Borisov, Sergey; Carvalho, Anna Cristina C; Chakaya, Jeremiah Muhwa; Cocco, Nicola; Codecasa, Luigi Ruffo; Dalcolmo, Margareth Pretti; Dheda, Keertan; Dinh-Xuan, Anh Tuan; Esposito, Susanna R; García-García, José-María; Li, Yang; Manga, Selene; Marchese, Valentina; Muñoz Torrico, Marcela; Pontali, Emanuele; Rendon, Adrián; Rossato Silva, Denise; Singla, Rupak; Solovic, Ivan; Sotgiu, Giovanni; van den Boom, Martin; Nhung, Nguyen Viet; Zellweger, Jean-Pierre; Migliori, Giovanni Battista; (2021) Screening for Tuberculosis in Migrants: A Survey by the Global Tuberculosis Network. Antibiotics (Basel, Switzerland), 10 (11). p. 1355. ISSN 2079-6382 DOI: https://doi.org/10.3390/antibiotics10111355

Davids, Malika; Pooran, Anil; Smith, Liezel; Tomasicchio, Michele; Dheda, Keertan; (2021) The Frequency and Effect of Granulocytic Myeloid-Derived Suppressor Cells on Mycobacterial Survival in Patients With Tuberculosis: A Preliminary Report. Frontiers in immunology, 12. 676679-. ISSN 1664-3224 DOI: https://doi.org/10.3389/fimmu.2021.676679

Dheda, K; Charalambous, S; Karat, AS; von Delft, A; Lalloo, UG; van Zyl Smit, R; Perumal, R; Allwood, BW; Esmail, A; Wong, ML; +21 more... Duse, AG; Richards, G; Feldman, C; Mer, M; Nyamande, K; Lalla, U; Koegelenberg, CFN; Venter, F; Dawood, H; Adams, S; Ntusi, NAB; van der Westhuizen, H-M; Moosa, M-YS; Martinson, NA; Moultrie, H; Nel, J; Hausler, H; Preiser, W; Lasersohn, L; Zar, HJ; Churchyard, GJ; (2021) A position statement and practical guide to the use of particulate filtering facepiece respirators (N95, FFP2, or equivalent) for South African health workers exposed to respiratory pathogens including Mycobacterium tuberculosis and SARS-CoV-2. African journal of thoracic and critical care medicine, 27 (4). pp. 177-186. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2021.v27i4.173

Dheda, K; Charalambous, S; Kharat, AS; von Delft, A; van Zyl-SMit, RN; Perumal, R; Allwood, BW; Esmail, A; Wong, ML; Duse, AG; +20 more... Richards, G; Feldman, C; Mer, M; Nyamande, K; Lalla, U; Koegelenberg, CFN; Venter, F; Dawood, H; Adams, S; Ntusi, NAB; van der Westhuizen, H-M; Moosa, M-YS; van der Westhuizen, NA; Moultrie, H; Nel, J; Hausler, H; Preiser, W; Lasersohn, L; Zar, HJ; Churchyard, GJ; (2021) A position statement and practical guide to the use of particulate filtering facepiece respirators (N95, FFP2, or equivalent) for South African health workers exposed to respiratory pathogens including Mycobacterium tuberculosis and SARS-CoV-2. African Journal of Thoracic and Critical Care Medicine, 24 (4). pp. 177-186. DOI: https://doi.org/10.7196/ajtccm.2021.v111i4.173

Janssen, Ricky; Engel, Nora; Pant Pai, Nitika; Esmail, Aliasgar; Dheda, Keertan; Thomas, Réjean; Krumeich, Anja; (2021) 'You're only there on the phone'? A qualitative exploration of community, affect and agential capacity in HIV self-testing using a smartphone app. Sociology of health & illness, 43 (3). pp. 591-606. ISSN 0141-9889 DOI: https://doi.org/10.1111/1467-9566.13242

Kohli, Mikashmi; Schiller, Ian; Dendukuri, Nandini; Yao, Mandy; Dheda, Keertan; Denkinger, Claudia M; Schumacher, Samuel G; Steingart, Karen R; (2021) Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults. The Cochrane database of systematic reviews, 1 (1). CD012768-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD012768.pub3

Madhi, Shabir A; Baillie, Vicky; Cutland, Clare L; Voysey, Merryn; Koen, Anthonet L; Fairlie, Lee; Padayachee, Sherman D; Dheda, Keertan; Barnabas, Shaun L; Bhorat, Qasim E; +43 more... Briner, Carmen; Kwatra, Gaurav; Ahmed, Khatija; Aley, Parvinder; Bhikha, Sutika; Bhiman, Jinal N; Bhorat, As'ad E; du Plessis, Jeanine; Esmail, Aliasgar; Groenewald, Marisa; Horne, Elizea; Hwa, Shi-Hsia; Jose, Aylin; Lambe, Teresa; Laubscher, Matt; Malahleha, Mookho; Masenya, Masebole; Masilela, Mduduzi; McKenzie, Shakeel; Molapo, Kgaogelo; Moultrie, Andrew; Oelofse, Suzette; Patel, Faeezah; Pillay, Sureshnee; Rhead, Sarah; Rodel, Hylton; Rossouw, Lindie; Taoushanis, Carol; Tegally, Houriiyah; Thombrayil, Asha; van Eck, Samuel; Wibmer, Constantinos K; Durham, Nicholas M; Kelly, Elizabeth J; Villafana, Tonya L; Gilbert, Sarah; Pollard, Andrew J; de Oliveira, Tulio; Moore, Penny L; Sigal, Alex; Izu, Alane; NGS-SA Group; Wits-VIDA COVID Group; (2021) Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant. The New England journal of medicine, 384 (20). pp. 1885-1898. ISSN 0028-4793 DOI: https://doi.org/10.1056/NEJMoa2102214

Madhi, Shabir A; Koen, Anthonet L; Izu, Alane; Fairlie, Lee; Cutland, Clare L; Baillie, Vicky; Padayachee, Sherman D; Dheda, Keertan; Barnabas, Shaun L; Bhorat, Qasim Ebrahim; +29 more... Briner, Carmen; Aley, Parvinder K; Bhikha, Sutika; Hermanus, Tandile; Horne, Elizea; Jose, Aylin; Kgagudi, Prudence; Lambe, Teresa; Masenya, Masebole; Masilela, Mduduzi; Mkhize, Nonhlanhla; Moultrie, Andrew; Mukendi, Christian K; Moyo-Gwete, Thandeka; Nana, Amit J; Nzimande, Ayanda; Patel, Faeezah; Rhead, Sarah; Taoushanis, Carol; Thombrayil, Asha; van Eck, Samuel; Voysey, Merryn; Villafana, Tonya L; Vekemans, Johan; Gilbert, Sarah C; Pollard, Andrew J; Moore, Penny L; Kwatra, Gaurav; Wits VIDA COVID team; Wits VIDA COVID team; (2021) Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in people living with and without HIV in South Africa: an interim analysis of a randomised, double-blind, placebo-controlled, phase 1B/2A trial. The lancet. HIV, 8 (9). e568-e580. ISSN 2405-4704 DOI: https://doi.org/10.1016/S2352-3018(21)00157-0

Metcalfe, John; Bacchetti, Peter; Esmail, Ali; Reckers, Andrew; Aguilar, David; Wen, Anita; Huo, Shu; Muyindike, Winnie R; Hahn, Judith A; Dheda, Keertan; +2 more... Gandhi, Monica; Gerona, Roy; (2021) Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting. BMC infectious diseases, 21 (1). 99-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-020-05738-5

Michell, WL; Joubert, IA; Peters, S; Fredericks, DL; Miller, MGA; Piercy, JL; Arnold-Day, C; Thomson, DA; van Zyl-Smit, RN; Calligaro, G; +5 more... Strathie, G; Semple, PL; Hofmeyr, R; Peters, D; Dheda, K; (2021) The organisational response of a hospital critical care service to the COVID-19 pandemic: The Groote Schuur Hospital experience. Southern African Journal of Critical Care, 37 (2). p. 63. ISSN 1562-8264 DOI: https://doi.org/10.7196/SAJCC.2021.v37i2.503

Oelofse, S; Esmail, A; Diacon, AH; Conradie, F; Olayanju, O; Ngubane, N; Howell, P; Everitt, D; Crook, AM; Mendel, CM; +7 more... Wills, GH; Olugbosi, M; Del Parigi, A; Sun, E; Calatroni, A; Spigelman, M; Dheda, K; (2021) Pretomanid with bedaquiline and linezolid for drug-resistant TB: a comparison of prospective cohorts. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 25 (6). pp. 453-460. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.21.0035

Pai, Nitika; Esmail, Aliasgar; Saha Chaudhuri, Paramita; Oelofse, Suzette; Pretorius, Marietjie; Marathe, Gayatri; Daher, Jana; Smallwood, Megan; Karatzas, Nicolaos; Fadul, Mohammed; +4 more... de Waal, Anna; Engel, Nora; Zwerling, Alice Anne; Dheda, Keertan; (2021) Impact of a personalised, digital, HIV self-testing app-based program on linkages and new infections in the township populations of South Africa. BMJ global health, 6 (9). e006032-e006032. ISSN 2059-7908 DOI: https://doi.org/10.1136/bmjgh-2021-006032

Raine, R; Dheda, K; (2021) Management of Acinetobacter baumannii infection in intensive care units. African journal of thoracic and critical care medicine, 27 (1). p. 5. ISSN 2617-0191 DOI: https://doi.org/10.7196/AJTCCM.2021.v27i1.143

Shinde, Vivek; Bhikha, Sutika; Hoosain, Zaheer; Archary, Moherndran; Bhorat, Qasim; Fairlie, Lee; Lalloo, Umesh; Masilela, Mduduzi SL; Moodley, Dhayendre; Hanley, Sherika; +40 more... Fouche, Leon; Louw, Cheryl; Tameris, Michele; Singh, Nishanta; Goga, Ameena; Dheda, Keertan; Grobbelaar, Coert; Kruger, Gertruida; Carrim-Ganey, Nazira; Baillie, Vicky; de Oliveira, Tulio; Lombard Koen, Anthonet; Lombaard, Johan J; Mngqibisa, Rosie; Bhorat, As'ad E; Benadé, Gabriella; Lalloo, Natasha; Pitsi, Annah; Vollgraaff, Pieter-Louis; Luabeya, Angelique; Esmail, Aliasgar; Petrick, Friedrich G; Oommen-Jose, Aylin; Foulkes, Sharne; Ahmed, Khatija; Thombrayil, Asha; Fries, Lou; Cloney-Clark, Shane; Zhu, Mingzhu; Bennett, Chijioke; Albert, Gary; Faust, Emmanuel; Plested, Joyce S; Robertson, Andreana; Neal, Susan; Cho, Iksung; Glenn, Greg M; Dubovsky, Filip; Madhi, Shabir A; 2019nCoV-501 Study Group; (2021) Efficacy of NVX-CoV2373 Covid-19 Vaccine against the B.1.351 Variant. The New England journal of medicine, 384 (20). pp. 1899-1909. ISSN 0028-4793 DOI: https://doi.org/10.1056/NEJMoa2103055

Tavaziva, Gamuchirai; Harris, Miriam; Abidi, Syed K; Geric, Coralie; Breuninger, Marianne; Dheda, Keertan; Esmail, Aliasgar; Muyoyeta, Monde; Reither, Klaus; Majidulla, Arman; +9 more... Khan, Aamir J; Campbell, Jonathon R; David, Pierre-Marie; Denkinger, Claudia; Miller, Cecily; Nathavitharana, Ruvandhi; Pai, Madhukar; Benedetti, Andrea; Ahmad Khan, Faiz; (2021) Chest X-ray Analysis With Deep Learning-Based Software as a Triage Test for Pulmonary Tuberculosis: An Individual Patient Data Meta-Analysis of Diagnostic Accuracy. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 74 (8). pp. 1390-1400. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciab639

Torrego, Alfons; Herth, Felix J; Munoz-Fernandez, Ana M; Puente, Luis; Facciolongo, Nicola; Bicknell, Stephen; Novali, Mauro; Gasparini, Stefano; Bonifazi, Martina; Dheda, Keertan; +12 more... Andreo, Felipe; Votruba, Praha; Langton, David; Flandes, Javier; Fielding, David; Bonta, Peter I; Skowasch, Dirk; Schulz, Christian; Darwiche, Kaid; McMullen, Edmund; Grubb, G Mark; Niven, Robert; (2021) Bronchial Thermoplasty Global Registry (BTGR): 2-year results. BMJ open, 11 (12). e053854. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2021-053854

Van Zyl-Smit, RN; Calligaro, GL; Dheda, K; Feldman, C; Kalla, IS; Koegelenberg, CFN; Lalloo, U; Perumal, R; Richards, GA; Wong, M; (2021) South african thoracic society position statement on post-acute sequelae of SARS-CoV-2 infection. African Journal of Thoracic and Critical Care Medicine, 27 (2). pp. 72-73. ISSN 2617-0191 https://researchonline.lshtm.ac.uk/id/eprint/4663707

Vishinkin, Rotem; Busool, Rami; Mansour, Elias; Fish, Falk; Esmail, Ali; Kumar, Parveen; Gharaa, Alaa; Cancilla, John C; Torrecilla, Jose S; Skenders, Girts; +4 more... Leja, Marcis; Dheda, Keertan; Singh, Sarman; Haick, Hossam; (2021) Profiles of Volatile Biomarkers Detect Tuberculosis from Skin. Advanced science (Weinheim, Baden-Wurttemberg, Germany), 8 (15). e2100235. ISSN 2198-3844 DOI: https://doi.org/10.1002/advs.202100235

Voysey, Merryn; Costa Clemens, Sue Ann; Madhi, Shabir A; Weckx, Lily Y; Folegatti, Pedro M; Aley, Parvinder K; Angus, Brian; Baillie, Vicky L; Barnabas, Shaun L; Bhorat, Qasim E; +71 more... Bhorat, Qasim E; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Clutterbuck, Elizabeth A; Collins, Andrea M; Cutland, Clare L; Darton, Thomas C; Dheda, Keertan; Dold, Christina; Duncan, Christopher JA; Emary, Katherine RW; Ewer, Katie J; Flaxman, Amy; Fairlie, Lee; Faust, Saul N; Feng, Shuo; Ferreira, Daniela M; Finn, Adam; Galiza, Eva; Goodman, Anna L; Green, Catherine M; Green, Christopher A; Greenland, Melanie; Hill, Catherine; Hill, Helen C; Hirsch, Ian; Izu, Alane; Jenkin, Daniel; Joe, Carina CD; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Libri, Vincenzo; Lillie, Patrick J; Marchevsky, Natalie G; Marshall, Richard P; Mendes, Ana VA; Milan, Eveline P; Minassian, Angela M; McGregor, Alastair; Mujadidi, Yama F; Nana, Anusha; Padayachee, Sherman D; Phillips, Daniel J; Pittella, Ana; Plested, Emma; Pollock, Katrina M; Ramasamy, Maheshi N; Ritchie, Adam J; Robinson, Hannah; Schwarzbold, Alexandre V; Smith, Andrew; Song, Rinn; Snape, Matthew D; Sprinz, Eduardo; Sutherland, Rebecca K; Thomson, Emma C; Török, M Estée; Toshner, Mark; Turner, David PJ; Vekemans, Johan; Villafana, Tonya L; White, Thomas; Williams, Christopher J; Douglas, Alexander D; Hill, Adrian VS; Lambe, Teresa; Gilbert, Sarah C; Pollard, Andrew J; Oxford COVID Vaccine Trial Group; (2021) Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials. Lancet (London, England), 397 (10277). pp. 881-891. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(21)00432-3

Calligaro, Gregory L; Lalla, Usha; Audley, Gordon; Gina, Phindile; Miller, Malcolm G; Mendelson, Marc; Dlamini, Sipho; Wasserman, Sean; Meintjes, Graeme; Peter, Jonathan; +13 more... Levin, Dion; Dave, Joel A; Ntusi, Ntobeko; Meier, Stuart; Little, Francesca; Moodley, Desiree L; Louw, Elizabeth H; Nortje, Andre; Parker, Arifa; Taljaard, Jantjie J; Allwood, Brian W; Dheda, Keertan; Koegelenberg, Coenraad FN; (2020) The utility of high-flow nasal oxygen for severe COVID-19 pneumonia in a resource-constrained setting: A multi-centre prospective observational study. EClinicalMedicine, 28. 100570-. ISSN 2589-5370 DOI: https://doi.org/10.1016/j.eclinm.2020.100570

Dheda, Keertan; Davids, Malika; (2020) LTBI-associated Immuno-diagnostic Test Responses (Standardized IGRAs and the TST) as Biomarkers of Incipient TB: Fruitful or Futile? American journal of respiratory and critical care medicine, 201 (8). pp. 895-898. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201912-2425ED

Dheda, Keertan; Makambwa, Edson; Esmail, Aliasgar; (2020) The Great Masquerader: Tuberculosis Presenting as Community-Acquired Pneumonia. SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE, 41 (4). pp. 592-604. ISSN 1069-3424 DOI: https://doi.org/10.1055/s-0040-1710583

Esmail, Aliasgar; Pooran, Anil; Sabur, Natasha F; Fadul, Mohammed; Brar, Mantaj S; Oelofse, Suzette; Tomasicchio, Michele; Dheda, Keertan; (2020) An Optimal Diagnostic Strategy for Tuberculosis in Hospitalized HIV-Infected Patients Using GeneXpert MTB/RIF and Alere Determine TB LAM Ag. JOURNAL OF CLINICAL MICROBIOLOGY, 58 (10). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.01032-20

Esmail, Aliasgar; Tomasicchio, Michele; Meldau, Richard; Makambwa, Edson; Dheda, Keertan; (2020) Comparison of Xpert MTB/RIF (G4) and Xpert Ultra, including trace readouts, for the diagnosis of pulmonary tuberculosis in a TB and HIV endemic setting. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 95. pp. 246-252. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2020.03.025

Ezewudo, Matthew; Borens, Amanda; Chiner-Oms, Álvaro; Miotto, Paolo; Chindelevitch, Leonid; Starks, Angela M; Hanna, Debra; Liwski, Richard; Zignol, Matteo; Gilpin, Christopher; +19 more... Niemann, Stefan; Kohl, Thomas Andreas; Warren, Robin M; Crook, Derrick; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; McNerney, Ruth; Cirillo, Daniela M; Schito, Marco; Rodwell, Timothy C; Posey, James; (2020) Author Correction: Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. Scientific reports, 10 (1). 3531-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-020-58955-y

Klopper, Marisa; Heupink, Tim Hermanus; Hill-Cawthorne, Grant; Streicher, Elizabeth Maria; Dippenaar, Anzaan; de Vos, Margaretha; Abdallah, Abdallah Musa; Limberis, Jason; Merker, Matthias; Burns, Scott; +5 more... Niemann, Stefan; Dheda, Keertan; Posey, James; Pain, Arnab; Warren, Robin Mark; (2020) A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic. BMC medicine, 18 (1). 24-. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-019-1487-2

Mottay, L; Le Roux, J; Perumal, R; Esmail, A; Timm, L; Sivarasu, S; Dheda, K; (2020) KN95 filtering facepiece respirators distributed in South Africa fail safety testing protocols. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. 13162-. ISSN 0256-9574 DOI: https://doi.org/10.7196/SAMJ.2021.v111i3.15381

Mthiyane, Thuli; Millard, James; Adamson, John; Balakrishna, Yusentha; Connolly, Cathy; Owen, Andrew; Rustomjee, Roxana; Dheda, Keertan; McIlleron, Helen; Pym, Alexander S; (2020) N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-lsoniazid Pharmacokinetics during Antituberculosis Treatment. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 64 (4). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02376-49

Mthiyane, Thuli; Millard, James; Adamson, John; Balakrishna, Yusentha; Connolly, Cathy; Owen, Andrew; Rustomjee, Roxana; Dheda, Keertan; McIlleron, Helen; Pym, Alexander S; (2020) N-Acetyltransferase 2 Genotypes among Zulu-Speaking South Africans and Isoniazid and N-Acetyl-Isoniazid Pharmacokinetics during Antituberculosis Treatment. Antimicrobial agents and chemotherapy, 64 (4). e02376-e02319. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02376-19

Tomasicchio, Michele; Limberis, Jason; van der Merwe, Ruben; Jacobson, Rachael; Meldau, Richard; Theron, Grant; Nicol, Mark; Warren, Rob; Dheda, Keertan; (2020) Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 96. pp. 240-243. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2020.04.053

Abdool-Gaffar, Mohamed Sabeer; Calligaro, Gregory; Wong, Michelle Lianne; Smith, Clifford; Lalloo, Umesh Gangaram; Koegelenberg, Coenraad Frederik Nicolaas; Dheda, Keertan; Allwood, Brian William; Goolam-Mahomed, Akhter; van Zyl-Smit, Richard Nellis; (2019) Management of chronic obstructive pulmonary disease-A position statement of the South African Thoracic Society: 2019 update. JOURNAL OF THORACIC DISEASE, 11 (11). pp. 4408-4427. ISSN 2072-1439 DOI: https://doi.org/10.21037/jtd.2019.10.65

Adams, Shahieda; Ehrlich, Rodney; Baatjies, Roslynn; Dendukuri, Nandini; Wang, Zhuoyu; Dheda, Keertan; (2019) Evaluating Latent Tuberculosis Infection Test Performance Using Latent Class Analysis in a TB and HIV Endemic Setting. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 16 (16). p. 2912. ISSN 1661-7827 DOI: https://doi.org/10.3390/ijerph16162912

Adams, Shahieda; Ehrlich, Rodney; Baatjies, Roslynn; Dendukuri, Nandini; Wang, Zhuoyu; Dheda, Keertan; (2019) Predictors of discordant latent tuberculosis infection test results amongst South African health care workers. BMC infectious diseases, 19 (1). 131-. DOI: https://doi.org/10.1186/s12879-019-3745-5

Davids, Malika; Pooran, Anil; Hermann, Clemens; Mottay, Lynelle; Thompson, Fawziyah; Cardenas, Jacob; Gu, Jinghua; Koeuth, Thearith; Meldau, Richard; Limberis, Jason; +8 more... Gina, Phindile; Srivastava, Shashikant; Calder, Bridget; Esmail, Aliasgar; Tomasicchio, Michele; Blackburn, Jonathan; Gumbo, Tawanda; Dheda, Keertan; (2019) A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin. American journal of respiratory and critical care medicine, 201 (10). pp. 1277-1291. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201908-1580OC

Dheda, Keertan; Lenders, Laura; Srivastava, Shashikant; Magombedze, Gesham; Wainwright, Helen; Raj, Prithvi; Bush, Stephen J; Pollara, Gabriele; Steyn, Rachelle; Davids, Malika; +11 more... Pooran, Anil; Pennel, Timothy; Linegar, Anthony; McNerney, Ruth; Moodley, Loven; Pasipanodya, Jotam G; Turner, Carolin T; Noursadeghi, Mahdad; Warren, Robin M; Wakeland, Edward; Gumbo, Tawanda; (2019) Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 200 (3). pp. 370-380. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201807-1361OC

Di Tanna, Gian Luca; Khaki, Ali Raza; Theron, Grant; McCarthy, Kerrigan; Cox, Helen; Mupfumi, Lucy; Trajman, Anete; Zijenah, Lynn Sodai; Mason, Peter; Bandason, Tsitsi; +14 more... Durovni, Betina; Bara, Wilbert; Hoelscher, Michael; Clowes, Petra; Mangu, Chacha; Chanda, Duncan; Pym, Alexander; Mwaba, Peter; Cobelens, Frank; Nicol, Mark P; Dheda, Keertan; Churchyard, Gavin; Fielding, Katherine; Metcalfe, John Z; (2019) Effect of Xpert MTB/RIF on clinical outcomes in routine care settings: individual patient data meta-analysis. LANCET GLOBAL HEALTH, 7 (2). e191-e199. ISSN 2214-109X DOI: https://doi.org/10.1016/S2214-109X(18)30458-3

Gupta-Wright, Ankur; Corbett, Elizabeth L; Wilson, Douglas; van Oosterhout, Joep J; Dheda, Keertan; Huerga, Helena; Peter, Jonny; Bonnet, Maryline; Alufandika-Moyo, Melanie; Grint, Daniel; +2 more... Lawn, Stephen D; Fielding, Katherine; (2019) Risk score for predicting mortality including urine lipoarabinomannan detection in hospital inpatients with HIV-associated tuberculosis in sub-Saharan Africa: Derivation and external validation cohort study. PLoS medicine, 16 (4). e1002776-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1002776

Hendricks, Rushdi; Davids, Malika; Khalfey, Hoosain; Landman, Hilda J; Theron, Anne E; Engela, Eugene; Dheda, Keertan; (2019) Sleepiness Score-Specific Outcomes of a Novel Tongue Repositioning Procedure for the Treatment of Continuous Positive Airway Pressure-Resistant Obstructive Sleep Apnea. Annals of Maxillofacial Surgery, 9 (1). pp. 28-36. ISSN 2231-0746 DOI: https://doi.org/10.4103/ams.ams_151_18

Janssen, Ricky; Engel, Nora; Esmail, Aliasgar; Oelofse, Suzette; Krumeich, Anja; Dheda, Keertan; Pai, Nitika Pant; (2019) Alone But Supported: A Qualitative Study of an HIV Self-testing App in an Observational Cohort Study in South Africa. AIDS and Behavior, 24 (2). pp. 467-474. ISSN 1090-7165 DOI: https://doi.org/10.1007/s10461-019-02516-6

Khan, Palwasha Y; Yates, Tom A; Osman, Muhammad; Warren, Robin M; van der Heijden, Yuri; Padayatchi, Nesri; Nardell, Edward A; Moore, David; Mathema, Barun; Gandhi, Neel; +6 more... Eldholm, Vegard; Dheda, Keertan; Hesseling, Anneke C; Mizrahi, Valerie; Rustomjee, Roxana; Pym, Alexander; (2019) Transmission of drug-resistant tuberculosis in HIV-endemic settings. LANCET INFECTIOUS DISEASES, 19 (3). e77-e88. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(18)30537-1

Koegelenberg, Coenraad FN; Dorfman, Shane; Schewitz, Ivan; Richards, Guy A; Maasdorp, Shaun; Smith, Clifford; Dheda, Keertan; (2019) Recommendations for lung cancer screening in Southern Africa. JOURNAL OF THORACIC DISEASE, 11 (9). pp. 3696-3703. ISSN 2072-1439 DOI: https://doi.org/10.21037/jtd.2019.08.66

Meldau, Richard; Randall, Philippa; Pooran, Anil; Limberis, Jason; Makambwa, Edson; Dhansay, Muhammed; Esmail, Aliasgar; Dheda, Keertan; (2019) Same-Day Tools, Including Xpert Ultra and IRISA-TB, for Rapid Diagnosis of Pleural Tuberculosis: a Prospective Observational Study. Journal of clinical microbiology, 57 (9). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.00614-19

Metcalfe, John; Bacchetti, Peter; Gerona, Roy; Esmail, Ali; Dheda, Keertan; Gandhi, Monica; (2019) Association of anti-tuberculosis drug concentrations in hair and treatment outcomes in MDR- and XDR-TB. ERJ Open Research, 5 (2). 00046-2019. ISSN 2312-508X DOI: https://doi.org/10.1183/23120541.00046-2019

Naidoo, Poobalan; Esmail, Aliasgar; Peter, Jonathan G; Davids, Malika; Fadul, Mohammed; Dheda, Keertan; (2019) Does the use of adjunct urine lipopolysaccharide lipoarabinomannan in HIV-infected hospitalized patients reduce the utilization of healthcare resources? A post hoc analysis of the LAM multi-country randomized controlled trial. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 79. pp. 37-43. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2018.09.024

Olayanju, Olatunde; Esmail, Aliasgar; Limberis, Jason; Dheda, Keertan; (2019) A regimen containing bedaquiline and delamanid compared to bedaquiline in patients with drug-resistant tuberculosis. The European respiratory journal, 55 (1). p. 1901181. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01181-2019

Olayanju, Olatunde; Esmail, Aliasgar; Limberis, Jason; Gina, Phindile; Dheda, Keertan; (2019) Linezolid interruption in patients with fluoroquinolone-resistant tuberculosis receiving a bedaquiline-based treatment regimen. International journal of infectious diseases, 85. pp. 74-79. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2019.04.028

Pooran, Anil; Davids, Malika; Nel, Andrew; Shoko, Aubrey; Blackburn, Jonathan; Dheda, Keertan; (2019) IL-4 subverts mycobacterial containment in Mycobacterium tuberculosis-infected human macrophages. The European respiratory journal, 54 (2). p. 1802242. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.02242-2018

Pooran, Anil; Theron, Grant; Zijenah, Lynn; Chanda, Duncan; Clowes, Petra; Mwenge, Lawrence; Mutenherwa, Farirai; Lecesse, Paul; Metcalfe, John; Sohn, Hojoon; +5 more... Hoelscher, Michael; Pym, Alex; Peter, Jonny; Dowdy, David; Dheda, Keertan; (2019) Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation. LANCET GLOBAL HEALTH, 7 (6). e798-e807. DOI: https://doi.org/10.1016/S2214-109X(19)30164-0

Sharma, Surendra K; Dheda, Keertan; (2019) What is new in the WHO consolidated guidelines on drug-resistant tuberculosis treatment? INDIAN JOURNAL OF MEDICAL RESEARCH, 149 (3). pp. 309-312. ISSN 0971-5916 DOI: https://doi.org/10.4103/ijmr.IJMR_579_19

Siddiqi, Omar K; Birbeck, Gretchen L; Ghebremichael, Musie; Mubanga, Eugene; Love, Shawn; Buback, Clayton; Kosloff, Barry; Ayles, Helen; Atadzhanov, Masharip; Dheda, Keertan; +1 more... Koralnik, Igor J; (2019) Prospective Cohort Study on Performance of Cerebrospinal Fluid (CSF) Xpert MTB/RIF, CSF Lipoarabinomannan (LAM) Lateral Flow Assay (LFA), and Urine LAM LFA for Diagnosis of Tuberculous Meningitis in Zambia. JOURNAL OF CLINICAL MICROBIOLOGY, 57 (8). ISSN 0095-1137 DOI: https://doi.org/10.1128/JCM.00652-19

Tadzimirwa, GY; Day, C; Esmail, A; Cooper, C; Kamkuemah, M; Dheda, K; Van Zyl-Smit, RN; (2019) Challenges for dedicated smoking cessation services in developing countries. SAMJ SOUTH AFRICAN MEDICAL JOURNAL, 109 (6). pp. 431-436. ISSN 0256-9574 DOI: https://doi.org/10.7196/SAMJ.2019.v109i6.13631

Tamgue, Ousman; Gcanga, Lorna; Ozturk, Mumin; Whitehead, Lauren; Pillay, Shandre; Jacobs, Raygaana; Roy, Sugata; Schmeier, Sebastian; Davids, Malika; Medvedeva, Yulia A; +4 more... Dheda, Keertan; Suzuki, Harukazu; Brombacher, Frank; Guler, Reto; (2019) Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages. Frontiers in immunology, 10 (MAR). 421-. DOI: https://doi.org/10.3389/fimmu.2019.00421

Te Riele, JB; Buser, V; Calligaro, G; Esmail, A; Theron, G; Lesosky, M; Dheda, K; (2019) Relationship between chest radiographic characteristics, sputum bacterial load, and treatment outcomes in patients with extensively drug-resistant tuberculosis. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 79. pp. 65-71. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2018.10.026

Tomasicchio, Michele; Semple, Lynn; Esmail, Aliasgar; Meldau, Richard; Randall, Philippa; Pooran, Anil; Davids, Malika; Cairncross, Lydia; Anderson, David; Downs, Jennifer; +7 more... Malherbe, Francois; Novitzky, Nicolas; Panieri, Eugenio; Oelofse, Suzette; Londt, Rolanda; Naiker, Thurandrie; Dheda, Keertan; (2019) An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells. CANCER IMMUNOLOGY IMMUNOTHERAPY, 68 (1). pp. 71-83. ISSN 0340-7004 DOI: https://doi.org/10.1007/s00262-018-2238-5

Wasserman, Sean; Denti, Paolo; Brust, James CM; Abdelwahab, Mahmoud; Hlungulu, Siphokazi; Wiesner, Lubbe; Norman, Jennifer; Sirgel, Frederick A; Warren, Robin M; Esmail, Aliasgar; +4 more... Dheda, Keertan; Gandhi, Neel R; Meintjes, Graeme; Maartens, Gary; (2019) Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection. Antimicrobial agents and chemotherapy, 63 (3). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02164-18

Aggerbeck, Henrik; Ruhwald, Morten; Hoff, Søren T; Borregaard, Bettine; Hellstrom, Elizabeth; Malahleha, Mookho; Siebert, Mirna; Gani, Mashra; Seopela, Vincent; Diacon, Andreas; +3 more... Lourens, Madeleine; Andersen, Peter; Dheda, Keertan; (2018) C-Tb skin test to diagnose Mycobacterium tuberculosis infection in children and HIV-infected adults: A phase 3 trial. PLOS ONE, 13 (9). e0204554-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0204554

Beynon, Fenella; Theron, Grant; Respeito, Durval; Mambuque, Edson; Saavedra, Belen; Bulo, Helder; Sanz, Sergi; Dheda, Keertan; Garcia-Basteiro, Alberto L; (2018) Correlation of Xpert MTB/RIF with measures to assess Mycobacterium tuberculosis bacillary burden in high HIV burden areas of Southern Africa. Scientific reports, 8 (1). 5201-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-23066-2

Coll, Francesc; Phelan, Jody; Hill-Cawthorne, Grant A; Nair, Mridul B; Mallard, Kim; Ali, Shahjahan; Abdallah, Abdallah M; Alghamdi, Saad; Alsomali, Mona; Ahmed, Abdallah O; +41 more... Portelli, Stephanie; Oppong, Yaa; Alves, Adriana; Bessa, Theolis Barbosa; Campino, Susana; Caws, Maxine; Chatterjee, Anirvan; Crampin, Amelia C; Dheda, Keertan; Furnham, Nicholas; Glynn, Judith R; Grandjean, Louis; Ha, Dang Minh; Hasan, Rumina; Hasan, Zahra; Hibberd, Martin L; Joloba, Moses; Jones-López, Edward C; Matsumoto, Tomoshige; Miranda, Anabela; Moore, David J; Mocillo, Nora; Panaiotov, Stefan; Parkhill, Julian; Penha, Carlos; Perdigão, João; Portugal, Isabel; Rchiad, Zineb; Robledo, Jaime; Sheen, Patricia; Shesha, Nashwa Talaat; Sirgel, Frik A; Sola, Christophe; Sousa, Erivelton Oliveira; Streicher, Elizabeth M; Van Helden, Paul; Viveiros, Miguel; Warren, Robert M; McNerney, Ruth; Pain, Arnab; Clark, Taane G; (2018) Author Correction: Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature genetics, 50 (5). 764-. ISSN 1061-4036 DOI: https://doi.org/10.1038/s41588-018-0074-3 Full text not available from this repository.

Coll, Francesc; Phelan, Jody; Hill-Cawthorne, Grant A; Nair, Mridul B; Mallard, Kim; Ali, Shahjahan; Abdallah, Abdallah M; Alghamdi, Saad; Alsomali, Mona; Ahmed, Abdallah O; +41 more... Portelli, Stephanie; Oppong, Yaa; Alves, Adriana; Bessa, Theolis Barbosa; Campino, Susana; Caws, Maxine; Chatterjee, Anirvan; Crampin, Amelia C; Dheda, Keertan; Furnham, Nicholas; Glynn, Judith R; Grandjean, Louis; Minh Ha, Dang; Hasan, Rumina; Hasan, Zahra; Hibberd, Martin L; Joloba, Moses; Jones-López, Edward C; Matsumoto, Tomoshige; Miranda, Anabela; Moore, David J; Mocillo, Nora; Panaiotov, Stefan; Parkhill, Julian; Penha, Carlos; Perdigão, João; Portugal, Isabel; Rchiad, Zineb; Robledo, Jaime; Sheen, Patricia; Shesha, Nashwa Talaat; Sirgel, Frik A; Sola, Christophe; Oliveira Sousa, Erivelton; Streicher, Elizabeth M; Helden, Paul Van; Viveiros, Miguel; Warren, Robert M; McNerney, Ruth; Pain, Arnab; Clark, Taane G; (2018) Genome-wide analysis of multi- and extensively drug-resistant Mycobacterium tuberculosis. Nature genetics, 50 (2). pp. 307-316. ISSN 1061-4036 DOI: https://doi.org/10.1038/s41588-017-0029-0

Deshpande, Devyani; Srivastava, Shashikant; Bendet, Paula; Martin, Katherine R; Cirrincione, Kayle N; Lee, Pooi S; Pasipanodya, Jotam G; Dheda, Keertan; Gumbo, Tawanda; (2018) Antibacterial and Sterilizing Effect of Benzylpenicillin in Tuberculosis. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 62 (2). ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.02232-17

Ezewudo, Matthew; Borens, Amanda; Chiner-Oms, Álvaro; Miotto, Paolo; Chindelevitch, Leonid; Starks, Angela M; Hanna, Debra; Liwski, Richard; Zignol, Matteo; Gilpin, Christopher; +19 more... Niemann, Stefan; Kohl, Thomas Andreas; Warren, Robin M; Crook, Derrick; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; McNerney, Ruth; Cirillo, Daniela M; Schito, Marco; Rodwell, Timothy C; Posey, James; (2018) Integrating standardized whole genome sequence analysis with a global Mycobacterium tuberculosis antibiotic resistance knowledgebase. SCIENTIFIC REPORTS, 8 (1). 15382-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-33731-1

Kohli, Mikashmi; Schiller, Ian; Dendukuri, Nandini; Dheda, Keertan; Denkinger, Claudia M; Schumacher, Samuel G; Steingart, Karen R; (2018) Xpert® MTB/RIF assay for extrapulmonary tuberculosis and rifampicin resistance. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 8 (8). CD012768-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD012768.pub2

Pham, Thu Hang; Peter, Jonathan; Mello, Fernanda CQ; Parraga, Tommy; Lan, Nguyen Thi Ngoc; Nabeta, Pamela; Valli, Eloise; Caceres, Tatiana; Dheda, Keertan; Dorman, Susan E; +3 more... Hillemann, Doris; Gray, Christen M; Perkins, Mark D; (2018) Performance of the TB-LAMP diagnostic assay in reference laboratories: Results from a multicentre study. International journal of infectious diseases, 68. pp. 44-49. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2018.01.005

Seipone, Ikanyeng D; Singh, Ravesh; Patel, Vinod B; Singh, Avashna; Gordon, Michelle L; Muema, Daniel M; Dheda, Keertan; Ndung'u, Thumbi; (2018) Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides. PLOS ONE, 13 (2). e0192060-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0192060

Sharma, Surendra Kumar; Mohan, Alladi; Singh, Achintya Dinesh; Mishra, Hridesh; Jhanjee, Sonali; Pandey, Ravindra Mohan; Singh, Binit Kumar; Sharma, Rohini; Pallipamu, Prakash Babu; Pai, Madhukar; +1 more... Dheda, Keertan; (2018) Impact of nicotine replacement therapy as an adjunct to anti-tuberculosis treatment and behaviour change counselling in newly diagnosed pulmonary tuberculosis patients: an open-label, randomised controlled trial. SCIENTIFIC REPORTS, 8 (1). 8828-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-26990-5

Tomasicchio, Michele; Davids, Malika; Pooran, Anil; Theron, Grant; Smith, Liezel; Semple, Lynn; Meldau, Richard; Hapgood, Janet Patricia; Dheda, Keertan; (2018) The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor. The Journal of infectious diseases, 219 (8). pp. 1329-1337. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiy657

Daher, Jana; Vijh, Rohit; Linthwaite, Blake; Dave, Sailly; Kim, John; Dheda, Keertan; Peter, Trevor; Pai, Nitika Pant; (2017) Do digital innovations for HIV and sexually transmitted infections work? Results from a systematic review (1996-2017). BMJ OPEN, 7 (11). e017604-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-017604

Deshpande, Devyani; Srivastava, Shashikant; Chapagain, Moti; Magombedze, Gesham; Martin, Katherine R; Cirrincione, Kayle N; Lee, Pooi S; Koeuth, Thearith; Dheda, Keertan; Gumbo, Tawanda; (2017) Ceftazidime-avibactam has potent sterilizing activity against highly drug-resistant tuberculosis. SCIENCE ADVANCES, 3 (8). e1701102-. ISSN 2375-2548 DOI: https://doi.org/10.1126/sciadv.1701102

Dheda, Keertan; Gumbo, Tawanda; Maartens, Gary; Dooley, Kelly E; McNerney, Ruth; Murray, Megan; Furin, Jennifer; Nardell, Edward A; London, Leslie; Lessem, Erica; +32 more... Theron, Grant; van Helden, Paul; Niemann, Stefan; Merker, Matthias; Dowdy, David; Van Rie, Annelies; Siu, Gilman KH; Pasipanodya, Jotam G; Rodrigues, Camilla; Clark, Taane G; Sirgel, Frik A; Esmail, Aliasgar; Lin, Hsien-Ho; Atre, Sachin R; Schaaf, H Simon; Chang, Kwok Chiu; Lange, Christoph; Nahid, Payam; Udwadia, Zarir F; Horsburgh, C Robert; Churchyard, Gavin J; Menzies, Dick; Hesseling, Anneke C; Nuermberger, Eric; McIlleron, Helen; Fennelly, Kevin P; Goemaere, Eric; Jaramillo, Ernesto; Low, Marcus; Jara, Carolina Morán; Padayatchi, Nesri; Warren, Robin M; (2017) The epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant, extensively drug-resistant, and incurable tuberculosis. The lancet Respiratory medicine, 5 (4). pp. 291-360. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(17)30079-6 Full text not available from this repository.

Dheda, Keertan; Limberis, Jason D; Pietersen, Elize; Phelan, Jody; Esmail, Aliasgar; Lesosky, Maia; Fennelly, Kevin P; Te Riele, Julian; Mastrapa, Barbara; Streicher, Elizabeth M; +13 more... Dolby, Tania; Abdallah, Abdallah M; Ben-Rached, Fathia; Simpson, John; Smith, Liezel; Gumbo, Tawanda; van Helden, Paul; Sirgel, Frederick A; McNerney, Ruth; Theron, Grant; Pain, Arnab; Clark, Taane G; Warren, Robin M; (2017) Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study. The lancet Respiratory medicine, 5 (4). pp. 269-281. ISSN 2213-2600 DOI: https://doi.org/10.1016/S2213-2600(16)30433-7 Full text not available from this repository.

Dowdy, David W; Grant, Alison D; Dheda, Keertan; Nardell, Edward; Fielding, Katherine; Moore, David AJ; (2017) Designing and Evaluating Interventions to Halt the Transmission of Tuberculosis. The Journal of infectious diseases, 216 (suppl_). S654-S661. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jix320

Engel, Nora; Davids, Malika; Blankvoort, Nadine; Dheda, Keertan; Pant Pai, Nitika; Pai, Madhukar; (2017) Making HIV testing work at the point of care in South Africa: a qualitative study of diagnostic practices. BMC HEALTH SERVICES RESEARCH, 17 (1). 408-. ISSN 1472-6963 DOI: https://doi.org/10.1186/s12913-017-2353-6

Gina, Phindile; Randall, Philippa J; Muchinga, Tapuwa E; Pooran, Anil; Meldau, Richard; Peter, Jonny G; Dheda, Keertan; (2017) Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection. BMC INFECTIOUS DISEASES, 17 (1). 339-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-017-2313-0

Lange, B; Khan, P; Kalmambetova, G; Al-Darraji, HA; Alland, D; Antonenka, U; Brown, T; Balcells, ME; Blakemore, R; Denkinger, CM; +14 more... Dheda, K; Hoffmann, H; Kadyrov, A; Lemaitre, N; Miller, MB; Nikolayevskyy, V; Ntinginya, EN; Ozkutuk, N; Palacios, JJ; Popowitch, EB; Porcel, JM; Teo, J; Theron, G; Kranzer, K; (2017) Diagnostic accuracy of the Xpert® MTB/RIF cycle threshold level to predict smear positivity: a meta-analysis. The international journal of tuberculosis and lung disease, 21 (5). pp. 493-502. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.16.0702 Full text not available from this repository.

Miotto, Paolo; Tessema, Belay; Tagliani, Elisa; Chindelevitch, Leonid; Starks, Angela M; Emerson, Claudia; Hanna, Debra; Kim, Peter S; Liwski, Richard; Zignol, Matteo; +25 more... Gilpin, Christopher; Niemann, Stefan; Denkinger, Claudia M; Fleming, Joy; Warren, Robin M; Crook, Derrick; Posey, James; Gagneux, Sebastien; Hoffner, Sven; Rodrigues, Camilla; Comas, Iñaki; Engelthaler, David M; Murray, Megan; Alland, David; Rigouts, Leen; Lange, Christoph; Dheda, Keertan; Hasan, Rumina; Ranganathan, Uma Devi K; McNerney, Ruth; Ezewudo, Matthew; Cirillo, Daniela M; Schito, Marco; Köser, Claudio U; Rodwell, Timothy C; (2017) A standardised method for interpreting the association between mutations and phenotypic drug resistance in Mycobacterium tuberculosis. EUROPEAN RESPIRATORY JOURNAL, 50 (6). p. 1701354. ISSN 0903-1936 DOI: https://doi.org/10.1183/13993003.01354-2017

Nasejje, Justine B; Mwambi, Henry; Dheda, Keertan; Lesosky, Maia; (2017) A comparison of the conditional inference survival forest model to random survival forests based on a simulation study as well as on two applications with time-to-event data. BMC MEDICAL RESEARCH METHODOLOGY, 17 (1). 115-. ISSN 1471-2288 DOI: https://doi.org/10.1186/s12874-017-0383-8

Sabur, Natasha F; Esmail, Aliasgar; Brar, Mantaj S; Dheda, Keertan; (2017) Diagnosing tuberculosis in hospitalized HIV-infected individuals who cannot produce sputum: is urine lipoarabinomannan testing the answer? BMC INFECTIOUS DISEASES, 17 (1). 803-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-017-2914-7

Furin, J; Alirol, E; Allen, E; Fielding, K; Merle, C; Abubakar, I; Andersen, J; Davies, G; Dheda, K; Diacon, A; +23 more... Dooley, KE; Dravnice, G; Eisenach, K; Everitt, D; Ferstenberg, D; Goolam-Mahomed, A; Grobusch, MP; Gupta, R; Harausz, E; Harrington, M; Horsburgh, CR; Lienhardt, C; McNeeley, D; Mitnick, CD; Nachman, S; Nahid, P; Nunn, AJ; Phillips, P; Rodriguez, C; Shah, S; Wells, C; Thomas-Nyang'wa, B; du Cros, P; (2016) Drug-resistant tuberculosis clinical trials: proposed core research definitions in adults. The international journal of tuberculosis and lung disease, 20 (3). pp. 290-294. ISSN 1027-3719 DOI: https://doi.org/10.5588/ijtld.15.0490 Full text not available from this repository.

Grobler, Liesl; Mehtar, Shaheen; Dheda, Keertan; Adams, Shahieda; Babatunde, Sanni; van der Walt, Martie; Osman, Muhammad; (2016) The epidemiology of tuberculosis in health care workers in South Africa: a systematic review. BMC HEALTH SERVICES RESEARCH, 16 (1). 416-. ISSN 1472-6963 DOI: https://doi.org/10.1186/s12913-016-1601-5

Lehloenya, Rannakoe J; Dlamini, Sipho; Muloiwa, Rudzani; Kakande, Betty; Ngwanya, Mzudumile R; Todd, Gail; Dheda, Keertan; (2016) Therapeutic Trial of Rifabutin After Rifampicin-Associated DRESS Syndrome in Tuberculosis-Human Immunodeficiency Virus Coinfected Patients. OPEN FORUM INFECTIOUS DISEASES, 3 (3). ofw130-. ISSN 2328-8957 DOI: https://doi.org/10.1093/ofid/ofw130

McNerney, Ruth; Clark, Taane G; Campino, Susana; Rodrigues, Camilla; Dolinger, David; Smith, Liezel; Cabibbe, Andrea M; Dheda, Keertan; Schito, Marco; (2016) Removing the bottleneck in whole genome sequencing of Mycobacterium tuberculosis for rapid drug resistance analysis: a call to action. International journal of infectious diseases, 56. pp. 130-135. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2016.11.422

Melendez, Jaime; Sánchez, Clara I; Philipsen, Rick HHM; Maduskar, Pragnya; Dawson, Rodney; Theron, Grant; Dheda, Keertan; van Ginneken, Bram; (2016) An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information. SCIENTIFIC REPORTS, 6 (1). 25265-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep25265

Pandie, Shaheen; Peter, Jonathan G; Kerbelker, Zita S; Meldau, Richard; Theron, Grant; Govender, Ureshnie; Ntsekhe, Mpiko; Dheda, Keertan; Mayosi, Bongani M; (2016) The diagnostic accuracy of pericardial and urinary lipoarabinomannan (LAM) assays in patients with suspected tuberculous pericarditis. SCIENTIFIC REPORTS, 6 (1). 32924-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep32924

Phelan, Jody E; Coll, Francesc; Bergval, Indra; Anthony, Richard M; Warren, Rob; Sampson, Samantha L; Gey van Pittius, Nicolaas C; Glynn, Judith R; Crampin, Amelia C; Alves, Adriana; +20 more... Bessa, Theolis Barbosa; Campino, Susana; Dheda, Keertan; Grandjean, Louis; Hasan, Rumina; Hasan, Zahra; Miranda, Anabela; Moore, David; Panaiotov, Stefan; Perdigao, Joao; Portugal, Isabel; Sheen, Patricia; de Oliveira Sousa, Erivelton; Streicher, Elizabeth M; van Helden, Paul D; Viveiros, Miguel; Hibberd, Martin L; Pain, Arnab; McNerney, Ruth; Clark, Taane G; (2016) Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages. BMC genomics, 17 (1). 151-. ISSN 1471-2164 DOI: https://doi.org/10.1186/s12864-016-2467-y

Phelan, Jody; O'Sullivan, Denise M; Machado, Diana; Ramos, Jorge; Whale, Alexandra S; O'Grady, Justin; Dheda, Keertan; Campino, Susana; McNerney, Ruth; Viveiros, Miguel; +2 more... Huggett, Jim F; Clark, Taane G; (2016) The variability and reproducibility of whole genome sequencing technology for detecting resistance to anti-tuberculous drugs. Genome medicine, 8 (1). 132-. ISSN 1756-994X DOI: https://doi.org/10.1186/s13073-016-0385-x

Senthilingam, Meera; Pietersen, Elize; McNerney, Ruth; Te Riele, Julian; Sedres, Pat; Wilson, Ruth; Dheda, Keertan; (2015) Lifestyle, attitudes and needs of uncured XDR-TB patients living in the communities of South Africa: a qualitative study. Tropical medicine & international health, 20 (9). pp. 1155-1161. ISSN 1360-2276 DOI: https://doi.org/10.1111/tmi.12532 Full text not available from this repository.

Lawn, Stephen D; Dheda, Keertan; Kerkhoff, Andrew D; Peter, Jonathan G; Dorman, Susan; Boehme, Catharina C; Nicol, Mark P; (2013) Determine TB-LAM lateral flow urine antigen assay for HIV-associated tuberculosis: recommendations on the design and reporting of clinical studies. BMC infectious diseases, 13 (1). 407-. ISSN 1471-2334 DOI: https://doi.org/10.1186/1471-2334-13-407

Pant Pai, Nitika; Sharma, Jigyasa; Shivkumar, Sushmita; Pillay, Sabrina; Vadnais, Caroline; Joseph, Lawrence; Dheda, Keertan; Peeling, Rosanna W; (2013) Supervised and unsupervised self-testing for HIV in high- and low-risk populations: a systematic review. PLoS medicine, 10 (4). e1001414-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001414

Anandaiah, Asha; Dheda, Keertan; Keane, Joseph; Koziel, Henry; Moore, David AJ; Patel, Naimish R; (2011) Novel developments in the epidemic of human immunodeficiency virus and tuberculosis coinfection. American journal of respiratory and critical care medicine, 183 (8). pp. 987-997. ISSN 1073-449X DOI: https://doi.org/10.1164/rccm.201008-1246CI Full text not available from this repository.

Tomlinson, Gillian S; Cashmore, Tamaryn J; Elkington, Paul TG; Yates, John; Lehloenya, Rannakoe J; Tsang, Jhen; Brown, Michael; Miller, Robert F; Dheda, Keertan; Katz, David R; +2 more... Chain, Benjamin M; Noursadeghi, Mahdad; (2011) Transcriptional profiling of innate and adaptive human immune responses to mycobacteria in the tuberculin skin test. European journal of immunology, 41 (11). pp. 3253-3260. ISSN 0014-2980 DOI: https://doi.org/10.1002/eji.201141841

Dheda, Keertan; Shean, Karen; Zumla, Alimuddin; Badri, Motasim; Streicher, Elizabeth M; Page-Shipp, Liesl; Willcox, Paul; John, Melanie-Anne; Reubenson, Gary; Govindasamy, Darshini; +13 more... Wong, Michelle; Padanilam, Xavier; Dziwiecki, Alicia; van Helden, Paul D; Siwendu, Sweetness; Jarand, Julie; Menezes, Colin N; Burns, Avril; Victor, Thomas; Warren, Robin; Grobusch, Martin P; van der Walt, Martie; Kvasnovsky, Charlotte; (2010) Early treatment outcomes and HIV status of patients with extensively drug-resistant tuberculosis in South Africa: a retrospective cohort study. Lancet, 375 (9728). pp. 1798-1807. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(10)60492-8

Hanekom, WA; Lawn, SD; Dheda, K; Whitelaw, A; (2010) Tuberculosis research update. Tropical medicine & international health, 15 (8). pp. 981-989. ISSN 1360-2276 DOI: https://doi.org/10.1111/j.1365-3156.2010.02568.x Full text not available from this repository.