Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

Voysey, Merryn; Costa Clemens, Sue Ann; Madhi, Shabir A; Weckx, Lily Y; Folegatti, Pedro M; Aley, Parvinder K; Angus, Brian; Baillie, Vicky L; Barnabas, Shaun L; Bhorat, Qasim E; +71 more... Bhorat, Qasim E; Bibi, Sagida; Briner, Carmen; Cicconi, Paola; Clutterbuck, Elizabeth A; Collins, Andrea M; Cutland, Clare L; Darton, Thomas C; Dheda, Keertan; Dold, Christina; Duncan, Christopher JA; Emary, Katherine RW; Ewer, Katie J; Flaxman, Amy; Fairlie, Lee; Faust, Saul N; Feng, Shuo; Ferreira, Daniela M; Finn, Adam; Galiza, Eva; Goodman, Anna L; Green, Catherine M; Green, Christopher A; Greenland, Melanie; Hill, Catherine; Hill, Helen C; Hirsch, Ian; Izu, Alane; Jenkin, Daniel; Joe, Carina CD; Kerridge, Simon; Koen, Anthonet; Kwatra, Gaurav; Lazarus, Rajeka; Libri, Vincenzo; Lillie, Patrick J; Marchevsky, Natalie G; Marshall, Richard P; Mendes, Ana VA; Milan, Eveline P; Minassian, Angela M; McGregor, Alastair; Mujadidi, Yama F; Nana, Anusha; Padayachee, Sherman D; Phillips, Daniel J; Pittella, Ana; Plested, Emma; Pollock, Katrina M; Ramasamy, Maheshi N; Ritchie, Adam J; Robinson, Hannah; Schwarzbold, Alexandre V; Smith, Andrew; Song, Rinn; Snape, Matthew D; Sprinz, Eduardo; Sutherland, Rebecca K; Thomson, Emma C; Török, M Estée; Toshner, Mark; Turner, David PJ; Vekemans, Johan; Villafana, Tonya L; White, Thomas; Williams, Christopher J; Douglas, Alexander D; Hill, Adrian VS; Lambe, Teresa; Gilbert, Sarah C; Pollard, Andrew J; Oxford COVID Vaccine Trial Group; (2021) Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials. Lancet (London, England), 397 (10277). pp. 881-891. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(21)00432-3

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