Items where Author or Contributor is "Delves, Michael J"
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Number of items: 66.
2024
Ashton, Trent D;
Calic, Petar PS;
Dans, Madeline G;
Kang Ooi, Zi;
Zhou, Qingmiao;
Loi, Katie;
Jarman, Kate E;
Palandri, Josephine;
Qiu, Deyun;
Lehane, Adele M;
+14 more...
Maity, Bikash;
De, Nirupam;
Famodimu, Mufuliat T;
Delves, Michael J;
Mao, Emma Y;
Gancheva, Maria R;
Wilson, Danny W;
Chowdury, Mrittika;
de Koning-Ward, Tania F;
Baud, Delphine;
Brand, Stephen;
Jackson, Paul F;
Cowman, Alan F;
Sleebs, Brad E;
(2024)
Lactam Truncation Yields a Dihydroquinazolinone Scaffold with Potent Antimalarial Activity that Targets PfATP4.
ChemMedChem.
e202400549-.
ISSN 1860-7179
DOI: https://doi.org/10.1002/cmdc.202400549
Awalt, Jon Kyle;
Su, Wenyin;
Nguyen, William;
Loi, Katie;
Jarman, Kate E;
Penington, Jocelyn S;
Ramesh, Saishyam;
Fairhurst, Kate J;
Yeo, Tomas;
Park, Heekuk;
+23 more...
Uhlemann, Anne-Catrin;
Chandra Maity, Bikash;
De, Nirupam;
Mukherjee, Partha;
Chakraborty, Arnish;
Churchyard, Alisje;
Famodimu, Mufuliat T;
Delves, Michael J;
Baum, Jake;
Mittal, Nimisha;
Winzeler, Elizabeth A;
Papenfuss, Anthony T;
Chowdury, Mrittika;
de Koning-Ward, Tania F;
Maier, Alexander G;
van Dooren, Giel G;
Baud, Delphine;
Brand, Stephen;
Fidock, David A;
Jackson, Paul F;
Cowman, Alan F;
Dans, Madeline G;
Sleebs, Brad E;
(2024)
Exploration and characterization of the antimalarial activity of cyclopropyl carboxamides that target the mitochondrial protein, cytochrome b.
European journal of medicinal chemistry, 280.
116921-.
ISSN 0223-5234
DOI: https://doi.org/10.1016/j.ejmech.2024.116921
Dans, Madeline G;
Boulet, Coralie;
Watson, Gabrielle M;
Nguyen, William;
Dziekan, Jerzy M;
Evelyn, Cindy;
Reaksudsan, Kitsanapong;
Mehra, Somya;
Razook, Zahra;
Geoghegan, Niall D;
+21 more...
Mlodzianoski, Michael J;
Goodman, Christopher Dean;
Ling, Dawson B;
Jonsdottir, Thorey K;
Tong, Joshua;
Famodimu, Mufuliat Toyin;
Kristan, Mojca;
Pollard, Harry;
Stewart, Lindsay B;
Brandner-Garrod, Luke;
Sutherland, Colin J;
Delves, Michael J;
McFadden, Geoffrey I;
Barry, Alyssa E;
Crabb, Brendan S;
de Koning-Ward, Tania F;
Rogers, Kelly L;
Cowman, Alan F;
Tham, Wai-Hong;
Sleebs, Brad E;
Gilson, Paul R;
(2024)
Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1.
Nature communications, 15 (1).
5219-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-024-49491-8
Higgins, Matthew;
Kristan, Mojca;
Collins, Emma L;
Messenger, Louisa A;
Dombrowski, Jamille G;
Vanheer, Leen N;
Nolder, Debbie;
Drakeley, Christopher J;
Stone, William;
Mahamar, Almahamoudou;
+12 more...
Bousema, Teun;
Delves, Michael;
Bandibabone, Janvier;
N'Do, Sévérin;
Bantuzeko, Chimanuka;
Zawadi, Bertin;
Walker, Thomas;
Sutherland, Colin J;
Marinho, Claudio RF;
Cameron, Mary M;
Clark, Taane G;
Campino, Susana;
(2024)
A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations.
Scientific reports, 14 (1).
20165-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-024-71129-4
Kumar, Amrendra;
Li, Yuexin;
Dodean, Rozalia A;
Roth, Alison;
Caridha, Diana;
Madejczyk, Michael S;
Jin, Xiannu;
Dennis, William E;
Lee, Patricia J;
Pybus, Brandon S;
+32 more...
Martin, Monica;
Pannone, Kristina;
Dinh, Hieu T;
Blount, Cameron;
Chetree, Ravi;
DeLuca, Jesse;
Evans, Martin;
Nadeau, Robert;
Vuong, Chau;
Leed, Susan;
Black, Chad;
Sousa, Jason;
Nolan, Christina;
Ceja, Frida G;
Rasmussen, Stephanie A;
Tumwebaze, Patrick K;
Rosenthal, Philip J;
Cooper, Roland A;
Rottmann, Matthias;
Orjuela-Sanchez, Pamela;
Meister, Stephan;
Winzeler, Elizabeth A;
Delves, Michael J;
Matthews, Holly;
Baum, Jake;
Kirby, Robert W;
Burrows, Jeremy N;
Duffy, James;
Peyton, David H;
Reynolds, Kevin A;
Kelly, Jane X;
Kancharla, Papireddy;
(2024)
Tambjamines as Fast-Acting Multistage Antimalarials.
ACS infectious diseases.
ISSN 2373-8227
DOI: https://doi.org/10.1021/acsinfecdis.4c00659
Item availability may be restricted.
Li, Yutong;
Cardoso-Silva, Jonathan;
Kelly, John M;
Delves, Michael J;
Furnham, Nicholas;
Papageorgiou, Lazaros G;
Tsoka, Sophia;
(2024)
Optimisation-based modelling for explainable lead discovery in malaria.
Artificial intelligence in medicine, 147.
102700-.
ISSN 0933-3657
DOI: https://doi.org/10.1016/j.artmed.2023.102700
2023
Racané, Livio;
Ptiček, Lucija;
Kostrun, Sanja;
Raić-Malić, Silvana;
Taylor, Martin Craig;
Delves, Michael;
Alsford, Sam;
Olmo, Francisco;
Francisco, Amanda Fortes;
Kelly, John M;
(2023)
Bis-6-amidino-benzothiazole Derivative that Cures Experimental Stage 1 African Trypanosomiasis with a Single Dose.
Journal of medicinal chemistry, 66 (18).
pp. 13043-13057.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.3c01051
Sparkes, PC;
(2023)
Exploring energy metabolism in male and female Plasmodium falciparum gametocytes.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04671600
Yahiya, Sabrina;
Saunders, Charlie N;
Hassan, Sarah;
Straschil, Ursula;
Fischer, Oliver J;
Rueda-Zubiaurre, Ainoa;
Haase, Silvia;
Vizcay-Barrena, Gema;
Famodimu, Mufuliat Toyin;
Jordan, Sarah;
+5 more...
Delves, Michael J;
Tate, Edward W;
Barnard, Anna;
Fuchter, Matthew J;
Baum, Jake;
(2023)
A novel class of sulphonamides potently block malaria transmission by targeting a Plasmodium vacuole membrane protein.
Disease models & mechanisms, 16 (2).
dmm049950-.
ISSN 1754-8403
DOI: https://doi.org/10.1242/dmm.049950
2021
Ellis, Katherine M;
Lucantoni, Leonardo;
Chavchich, Marina;
Abraham, Matthew;
De Paoli, Amanda;
Luth, Madeline R;
Zeeman, Anne-Marie;
Delves, Michael J;
Terán, Fernando Sánchez-Román;
Straschil, Ursula;
+8 more...
Baum, Jake;
Kocken, Clemens HM;
Ralph, Stuart A;
Winzeler, Elizabeth A;
Avery, Vicky M;
Edstein, Michael D;
Baell, Jonathan B;
Creek, Darren J;
(2021)
The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite.
Antimicrobial Agents and Chemotherapy, 65 (11).
e0031121-.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00311-21
Miguel-Blanco, Celia;
Murithi, James M;
Benavente, Ernest Diez;
Angrisano, Fiona;
Sala, Katarzyna A;
van Schalkwyk, Donelly A;
Vanaerschot, Manu;
Schwach, Frank;
Fuchter, Matthew J;
Billker, Oliver;
+9 more...
Sutherland, Colin J;
Campino, Susana G;
Clark, Taane G;
Blagborough, Andrew M;
Fidock, David A;
Herreros, Esperanza;
Gamo, Francisco Javier;
Baum, Jake;
Delves, Michael J;
(2021)
The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957.
Scientific reports, 11 (1).
1888-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-021-81343-z
Witmer, Kathrin;
Dahalan, Farah A;
Delves, Michael J;
Yahiya, Sabrina;
Watson, Oliver J;
Straschil, Ursula;
Chiwcharoen, Darunee;
Sornboon, Boodtee;
Pukrittayakamee, Sasithon;
Pearson, Richard D;
+8 more...
Howick, Virginia M;
Lawniczak, Mara KN;
White, Nicholas J;
Dondorp, Arjen M;
Okell, Lucy C;
Chotivanich, Kesinee;
Ruecker, Andrea;
Baum, Jake;
(2021)
Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 65 (1).
e00898-20.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00898-20
2020
Vanaerschot, Manu;
Murithi, James M;
Pasaje, Charisse Flerida A;
Ghidelli-Disse, Sonja;
Dwomoh, Louis;
Bird, Megan;
Spottiswoode, Natasha;
Mittal, Nimisha;
Arendse, Lauren B;
Owen, Edward S;
+21 more...
Wicht, Kathryn J;
Siciliano, Giulia;
Bösche, Markus;
Yeo, Tomas;
Kumar, TR Santha;
Mok, Sachel;
Carpenter, Emma F;
Giddins, Marla J;
Sanz, Olalla;
Ottilie, Sabine;
Alano, Pietro;
Chibale, Kelly;
Llinás, Manuel;
Uhlemann, Anne-Catrin;
Delves, Michael;
Tobin, Andrew B;
Doerig, Christian;
Winzeler, Elizabeth A;
Lee, Marcus CS;
Niles, Jacquin C;
Fidock, David A;
(2020)
Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity.
Cell chemical biology, 27 (7).
806-816.e8.
ISSN 2451-9456
DOI: https://doi.org/10.1016/j.chembiol.2020.04.001
2019
Baragaña, Beatriz;
Forte, Barbara;
Choi, Ryan;
Nakazawa Hewitt, Stephen;
Bueren-Calabuig, Juan A;
Pisco, João Pedro;
Peet, Caroline;
Dranow, David M;
Robinson, David A;
Jansen, Chimed;
+67 more...
Norcross, Neil R;
Vinayak, Sumiti;
Anderson, Mark;
Brooks, Carrie F;
Cooper, Caitlin A;
Damerow, Sebastian;
Delves, Michael;
Dowers, Karen;
Duffy, James;
Edwards, Thomas E;
Hallyburton, Irene;
Horst, Benjamin G;
Hulverson, Matthew A;
Ferguson, Liam;
Jiménez-Díaz, María Belén;
Jumani, Rajiv S;
Lorimer, Donald D;
Love, Melissa S;
Maher, Steven;
Matthews, Holly;
McNamara, Case W;
Miller, Peter;
O'Neill, Sandra;
Ojo, Kayode K;
Osuna-Cabello, Maria;
Pinto, Erika;
Post, John;
Riley, Jennifer;
Rottmann, Matthias;
Sanz, Laura M;
Scullion, Paul;
Sharma, Arvind;
Shepherd, Sharon M;
Shishikura, Yoko;
Simeons, Frederick RC;
Stebbins, Erin E;
Stojanovski, Laste;
Straschil, Ursula;
Tamaki, Fabio K;
Tamjar, Jevgenia;
Torrie, Leah S;
Vantaux, Amélie;
Witkowski, Benoît;
Wittlin, Sergio;
Yogavel, Manickam;
Zuccotto, Fabio;
Angulo-Barturen, Iñigo;
Sinden, Robert;
Baum, Jake;
Gamo, Francisco-Javier;
Mäser, Pascal;
Kyle, Dennis E;
Winzeler, Elizabeth A;
Myler, Peter J;
Wyatt, Paul G;
Floyd, David;
Matthews, David;
Sharma, Amit;
Striepen, Boris;
Huston, Christopher D;
Gray, David W;
Fairlamb, Alan H;
Pisliakov, Andrei V;
Walpole, Chris;
Read, Kevin D;
Van Voorhis, Wesley C;
Gilbert, Ian H;
(2019)
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Proceedings of the National Academy of Sciences of the United States of America, 116 (14).
pp. 7015-7020.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1814685116
Bradley, John;
Soumaré, Harouna M;
Mahamar, Almahamoudou;
Diawara, Halimatou;
Roh, Michelle;
Delves, Michael;
Drakeley, Chris;
Churcher, Thomas S;
Dicko, Alassane;
Gosling, Roly;
+1 more...
Bousema, Teun;
(2019)
Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio.
Clinical Infectious Diseases, 69 (8).
pp. 1436-1439.
ISSN 1058-4838
DOI: https://doi.org/10.1093/cid/ciz134
Children of Eden Primary School;
Straschil, Ursula;
Witmer, Kathrin;
Delves, Michael J;
Marks, Stephen D;
Baum, Jake;
(2019)
Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials.
Archives of disease in childhood, 104 (12).
pp. 1138-1142.
ISSN 0003-9888
DOI: https://doi.org/10.1136/archdischild-2019-317590
Delves, Michael;
Lafuente-Monasterio, M Jose;
Upton, Leanna;
Ruecker, Andrea;
Leroy, Didier;
Gamo, Francisco-Javier;
Sinden, Robert;
(2019)
Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages.
Frontiers in Microbiology, 10.
DOI: https://doi.org/10.3389/fmicb.2019.02134
Norcross, Neil R;
Wilson, Caroline;
Baragaña, Beatriz;
Hallyburton, Irene;
Osuna-Cabello, Maria;
Norval, Suzanne;
Riley, Jennifer;
Fletcher, Daniel;
Sinden, Robert;
Delves, Michael;
+18 more...
Ruecker, Andrea;
Duffy, Sandra;
Meister, Stephan;
Antonova-Koch, Yevgeniya;
Crespo, Benigno;
de Cózar, Cristina;
Sanz, Laura M;
Gamo, Francisco Javier;
Avery, Vicky M;
Frearson, Julie A;
Gray, David W;
Fairlamb, Alan H;
Winzeler, Elizabeth A;
Waterson, David;
Campbell, Simon F;
Willis, Paul A;
Read, Kevin D;
Gilbert, Ian H;
(2019)
Substituted Aminoacetamides as Novel Leads for Malaria Treatment.
ChemMedChem, 14 (14).
pp. 1329-1335.
ISSN 1860-7179
DOI: https://doi.org/10.1002/cmdc.201900329
Rueda-Zubiaurre, Ainoa;
Yahiya, Sabrina;
Fischer, Oliver J;
Hu, Xiaojun;
Saunders, Charlie N;
Sharma, Sachi;
Straschil, Ursula;
Shen, Junting;
Tate, Edward W;
Delves, Michael J;
+3 more...
Baum, Jake;
Barnard, Anna;
Fuchter, Matthew J;
(2019)
Structure-Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes.
Journal of medicinal chemistry, 63 (5).
pp. 2240-2262.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.9b00898
Yahiya, Sabrina;
Rueda-Zubiaurre, Ainoa;
Delves, Michael J;
Fuchter, Matthew J;
Baum, Jake;
(2019)
The antimalarial screening landscape-looking beyond the asexual blood stage.
Current Opinion in Chemical Biology, 50.
pp. 1-9.
ISSN 1367-5931
DOI: https://doi.org/10.1016/j.cbpa.2019.01.029
Zeeshan, Mohammad;
Ferguson, David Jp;
Abel, Steven;
Burrrell, Alana;
Rea, Edward;
Brady, Declan;
Daniel, Emilie;
Delves, Michael;
Vaughan, Sue;
Holder, Anthony A;
+3 more...
Le Roch, Karine G;
Moores, Carolyn A;
Tewari, Rita;
(2019)
Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission.
Life science alliance, 2 (4).
e201900488-e201900488.
ISSN 2575-1077
DOI: https://doi.org/10.26508/lsa.201900488
2018
Delves, MJ;
Angrisano, F;
Blagborough, AM;
(2018)
Antimalarial Transmission-Blocking Interventions: Past, Present, and Future.
Trends in parasitology, 34 (9).
pp. 735-746.
ISSN 1471-4922
DOI: https://doi.org/10.1016/j.pt.2018.07.001
Delves, Michael J;
Miguel-Blanco, Celia;
Matthews, Holly;
Molina, Irene;
Ruecker, Andrea;
Yahiya, Sabrina;
Straschil, Ursula;
Abraham, Matthew;
León, María Luisa;
Fischer, Oliver J;
+11 more...
Rueda-Zubiaurre, Ainoa;
Brandt, Jochen R;
Cortés, Álvaro;
Barnard, Anna;
Fuchter, Matthew J;
Calderón, Félix;
Winzeler, Elizabeth A;
Sinden, Robert E;
Herreros, Esperanza;
Gamo, Francisco J;
Baum, Jake;
(2018)
A high throughput screen for next-generation leads targeting malaria parasite transmission.
NATURE COMMUNICATIONS, 9 (1).
3805-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-018-05777-2
Malpartida-Cardenas, Kenny;
Rodriguez-Manzano, Jesus;
Yu, Ling-Shan;
Delves, Michael J;
Nguon, Chea;
Chotivanich, Kesinee;
Baum, Jake;
Georgiou, Pantelis;
(2018)
Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers.
ANALYTICAL CHEMISTRY, 90 (20).
pp. 11972-11980.
ISSN 0003-2700
DOI: https://doi.org/10.1021/acs.analchem.8b02416
Martí Coma-Cros, Elisabet;
Biosca, Arnau;
Marques, Joana;
Carol, Laura;
Urbán, Patricia;
Berenguer, Diana;
Riera, Maria Cristina;
Delves, Michael;
Sinden, Robert E;
Valle-Delgado, Juan José;
+9 more...
Spanos, Lefteris;
Siden-Kiamos, Inga;
Pérez, Paula;
Paaijmans, Krijn;
Rottmann, Matthias;
Manfredi, Amedea;
Ferruti, Paolo;
Ranucci, Elisabetta;
Fernàndez-Busquets, Xavier;
(2018)
Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs.
Pharmaceutics, 10 (4).
p. 225.
DOI: https://doi.org/10.3390/pharmaceutics10040225
Witmer, Kathrin;
Sherrard-Smith, Ellie;
Straschil, Ursula;
Tunnicliff, Mark;
Baum, Jake;
Delves, Michael;
(2018)
An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies.
Malaria journal, 17 (1).
282-.
ISSN 1475-2875
DOI: https://doi.org/10.1186/s12936-018-2436-9
2017
Leven, Michael;
Knaab, Tanja C;
Held, Jana;
Duffy, Sandra;
Meister, Stephan;
Fischli, Christoph;
Meitzner, Diane;
Lehmann, Ursula;
Lungerich, Beate;
Kuna, Krystina;
+8 more...
Stahlke, Petra;
Delves, Michael J;
Buchholz, Mirko;
Winzeler, Elizabeth A;
Avery, Vicky M;
Mordmüller, Benjamin;
Wittlin, Sergio;
Kurz, Thomas;
(2017)
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
Journal of medicinal chemistry, 60 (14).
pp. 6036-6044.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00140
Full text not available from this repository.
Miguel-Blanco, Celia;
Molina, Irene;
Bardera, Ana I;
Díaz, Beatriz;
de Las Heras, Laura;
Lozano, Sonia;
González, Carolina;
Rodrigues, Janneth;
Delves, Michael J;
Ruecker, Andrea;
+7 more...
Colmenarejo, Gonzalo;
Viera, Sara;
Martínez-Martínez, María S;
Fernández, Esther;
Baum, Jake;
Sinden, Robert E;
Herreros, Esperanza;
(2017)
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Nature communications, 8 (1).
15160-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms15160
O'Neill, Paul M;
Amewu, Richard K;
Charman, Susan A;
Sabbani, Sunil;
Gnädig, Nina F;
Straimer, Judith;
Fidock, David A;
Shore, Emma R;
Roberts, Natalie L;
Wong, Michael H-L;
+38 more...
Hong, W David;
Pidathala, Chandrakala;
Riley, Chris;
Murphy, Ben;
Aljayyoussi, Ghaith;
Gamo, Francisco Javier;
Sanz, Laura;
Rodrigues, Janneth;
Cortes, Carolina Gonzalez;
Herreros, Esperanza;
Angulo-Barturén, Iñigo;
Jiménez-Díaz, María Belén;
Bazaga, Santiago Ferrer;
Martínez-Martínez, María Santos;
Campo, Brice;
Sharma, Raman;
Ryan, Eileen;
Shackleford, David M;
Campbell, Simon;
Smith, Dennis A;
Wirjanata, Grennady;
Noviyanti, Rintis;
Price, Ric N;
Marfurt, Jutta;
Palmer, Michael J;
Copple, Ian M;
Mercer, Amy E;
Ruecker, Andrea;
Delves, Michael J;
Sinden, Robert E;
Siegl, Peter;
Davies, Jill;
Rochford, Rosemary;
Kocken, Clemens HM;
Zeeman, Anne-Marie;
Nixon, Gemma L;
Biagini, Giancarlo A;
Ward, Stephen A;
(2017)
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nature communications, 8 (1).
15159-.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms15159
Vanaerschot, Manu;
Lucantoni, Leonardo;
Li, Tao;
Combrinck, Jill M;
Ruecker, Andrea;
Kumar, TR Santha;
Rubiano, Kelly;
Ferreira, Pedro E;
Siciliano, Giulia;
Gulati, Sonia;
+16 more...
Henrich, Philipp P;
Ng, Caroline L;
Murithi, James M;
Corey, Victoria C;
Duffy, Sandra;
Lieberman, Ori J;
Veiga, M Isabel;
Sinden, Robert E;
Alano, Pietro;
Delves, Michael J;
Lee Sim, Kim;
Winzeler, Elizabeth A;
Egan, Timothy J;
Hoffman, Stephen L;
Avery, Vicky M;
Fidock, David A;
(2017)
Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.
Nature microbiology, 2 (10).
pp. 1403-1414.
ISSN 2058-5276
DOI: https://doi.org/10.1038/s41564-017-0007-4
Full text not available from this repository.
2016
Baragaña, Beatriz;
Norcross, Neil R;
Wilson, Caroline;
Porzelle, Achim;
Hallyburton, Irene;
Grimaldi, Raffaella;
Osuna-Cabello, Maria;
Norval, Suzanne;
Riley, Jennifer;
Stojanovski, Laste;
+17 more...
Simeons, Frederick RC;
Wyatt, Paul G;
Delves, Michael J;
Meister, Stephan;
Duffy, Sandra;
Avery, Vicky M;
Winzeler, Elizabeth A;
Sinden, Robert E;
Wittlin, Sergio;
Frearson, Julie A;
Gray, David W;
Fairlamb, Alan H;
Waterson, David;
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Kokkonda, Sreekanth;
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Delves, Michael;
Sinden, Robert;
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Science translational medicine, 7 (296).
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A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs.
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Marfurt, Jutta;
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Wirjanata, Grennady;
Sebayang, Boni F;
Price, Ric N;
Chatterjee, Arnab;
Nagle, Advait;
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Charman, Susan A;
Angulo-Barturen, Iñigo;
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Belén Jiménez-Díaz, María;
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Price, Ric N;
Avery, Vicky M;
Angulo-Barturen, Iñigo;
Jiménez-Díaz, María Belén;
Ferrer, Santiago;
Herreros, Esperanza;
Sanz, Laura M;
Gamo, Francisco-Javier;
Bathurst, Ian;
Burrows, Jeremy N;
Siegl, Peter;
Guy, R Kiplin;
Winter, Rolf W;
Vaidya, Akhil B;
Charman, Susan A;
Kyle, Dennis E;
Manetsch, Roman;
Riscoe, Michael K;
(2013)
Quinolone-3-diarylethers: a new class of antimalarial drug.
Science translational medicine, 5 (177).
177ra37-.
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.3005029
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Ramakrishnan, Chandra;
Delves, Michael J;
Lal, Kalpana;
Blagborough, Andrew M;
Butcher, Geoffrey;
Baker, Kenneth W;
Sinden, Robert E;
(2013)
Laboratory maintenance of rodent malaria parasites.
Methods in molecular biology (Clifton, NJ), 923.
pp. 51-72.
ISSN 1064-3745
DOI: https://doi.org/10.1007/978-1-62703-026-7_5
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2012
Angrisano, Fiona;
Riglar, David T;
Sturm, Angelika;
Volz, Jennifer C;
Delves, Michael J;
Zuccala, Elizabeth S;
Turnbull, Lynne;
Dekiwadia, Chaitali;
Olshina, Maya A;
Marapana, Danushka S;
+11 more...
Wong, Wilson;
Mollard, Vanessa;
Bradin, Clare H;
Tonkin, Christopher J;
Gunning, Peter W;
Ralph, Stuart A;
Whitchurch, Cynthia B;
Sinden, Robert E;
Cowman, Alan F;
McFadden, Geoffrey I;
Baum, Jake;
(2012)
Spatial localisation of actin filaments across developmental stages of the malaria parasite.
PloS one, 7 (2).
e32188-.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0032188
Biagini, Giancarlo A;
Fisher, Nicholas;
Shone, Alison E;
Mubaraki, Murad A;
Srivastava, Abhishek;
Hill, Alisdair;
Antoine, Thomas;
Warman, Ashley J;
Davies, Jill;
Pidathala, Chandrakala;
+22 more...
Amewu, Richard K;
Leung, Suet C;
Sharma, Raman;
Gibbons, Peter;
Hong, David W;
Pacorel, Bénédicte;
Lawrenson, Alexandre S;
Charoensutthivarakul, Sitthivut;
Taylor, Lee;
Berger, Olivier;
Mbekeani, Alison;
Stocks, Paul A;
Nixon, Gemma L;
Chadwick, James;
Hemingway, Janet;
Delves, Michael J;
Sinden, Robert E;
Zeeman, Anne-Marie;
Kocken, Clemens HM;
Berry, Neil G;
O'Neill, Paul M;
Ward, Stephen A;
(2012)
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proceedings of the National Academy of Sciences of the United States of America, 109 (21).
pp. 8298-8303.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1205651109
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Churcher, Thomas S;
Blagborough, Andrew M;
Delves, Michael;
Ramakrishnan, Chandra;
Kapulu, Melissa C;
Williams, Andrew R;
Biswas, Sumi;
Da, Dari F;
Cohuet, Anna;
Sinden, Robert E;
(2012)
Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding Assay.
International journal for parasitology, 42 (11).
pp. 1037-1044.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.09.002
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Delves, Michael J;
(2012)
Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs.
Future medicinal chemistry, 4 (18).
pp. 2251-2263.
ISSN 1756-8919
DOI: https://doi.org/10.4155/fmc.12.182
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Delves, Michael J;
Ramakrishnan, Chandra;
Blagborough, Andrew M;
Leroy, Didier;
Wells, Timothy NC;
Sinden, Robert E;
(2012)
A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines.
International journal for parasitology, 42 (11).
pp. 999-1006.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.08.009
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Delves, Michael;
Plouffe, David;
Scheurer, Christian;
Meister, Stephan;
Wittlin, Sergio;
Winzeler, Elizabeth A;
Sinden, Robert E;
Leroy, Didier;
(2012)
The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.
PLoS medicine, 9 (2).
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ISSN 1549-1277
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Sinden, Robert E;
Blagborough, Andrew M;
Churcher, Thomas;
Ramakrishnan, Chandra;
Biswas, Sumi;
Delves, Michael J;
(2012)
The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium.
Trends in parasitology, 28 (11).
pp. 457-465.
ISSN 1471-4922
DOI: https://doi.org/10.1016/j.pt.2012.07.005
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2011
Angrisano, Fiona;
Delves, Michael J;
Sturm, Angelika;
Mollard, Vanessa;
McFadden, Geoffrey I;
Sinden, Robert E;
Baum, Jake;
(2011)
A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle.
Molecular and biochemical parasitology, 182 (1-2).
pp. 93-96.
ISSN 0166-6851
DOI: https://doi.org/10.1016/j.molbiopara.2011.11.008
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Slavic, Ksenija;
Delves, Michael J;
Prudêncio, Miguel;
Talman, Arthur M;
Straschil, Ursula;
Derbyshire, Elvira T;
Xu, Zhengyao;
Sinden, Robert E;
Mota, Maria M;
Morin, Christophe;
+3 more...
Tewari, Rita;
Krishna, Sanjeev;
Staines, Henry M;
(2011)
Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle.
Antimicrobial agents and chemotherapy, 55 (6).
pp. 2824-2830.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.01739-10
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2010
Delves, Michael J;
Sinden, Robert E;
(2010)
A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies.
Malaria journal, 9 (1).
35-.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-9-35
2008
Lal, Kalpana;
Delves, Michael J;
Bromley, Elizabeth;
Wastling, Jonathan M;
Tomley, Fiona M;
Sinden, Robert E;
(2008)
Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development.
International journal for parasitology, 39 (7).
pp. 755-761.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2008.11.008
Full text not available from this repository.