Items where Author or Contributor is "Delves, Michael J"

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Number of items: 55.

2021

Miguel-Blanco, Celia; Murithi, James M; Benavente, Ernest Diez; Angrisano, Fiona; Sala, Katarzyna A; van Schalkwyk, Donelly A; Vanaerschot, Manu; Schwach, Frank; Fuchter, Matthew J; Billker, Oliver; +9 more... Sutherland, Colin J; Campino, Susana G; Clark, Taane G; Blagborough, Andrew M; Fidock, David A; Herreros, Esperanza; Gamo, Francisco Javier; Baum, Jake; Delves, Michael J; (2021) The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. Scientific reports, 11 (1). 1888-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-021-81343-z
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Witmer, Kathrin; Dahalan, Farah A; Delves, Michael J; Yahiya, Sabrina; Watson, Oliver J; Straschil, Ursula; Chiwcharoen, Darunee; Sornboon, Boodtee; Pukrittayakamee, Sasithon; Pearson, Richard D; +8 more... Howick, Virginia M; Lawniczak, Mara KN; White, Nicholas J; Dondorp, Arjen M; Okell, Lucy C; Chotivanich, Kesinee; Ruecker, Andrea; Baum, Jake; (2021) Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 65 (1). e00898-20. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00898-20
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2019

Baragaña, Beatriz; Forte, Barbara; Choi, Ryan; Nakazawa Hewitt, Stephen; Bueren-Calabuig, Juan A; Pisco, João Pedro; Peet, Caroline; Dranow, David M; Robinson, David A; Jansen, Chimed; +67 more... Norcross, Neil R; Vinayak, Sumiti; Anderson, Mark; Brooks, Carrie F; Cooper, Caitlin A; Damerow, Sebastian; Delves, Michael; Dowers, Karen; Duffy, James; Edwards, Thomas E; Hallyburton, Irene; Horst, Benjamin G; Hulverson, Matthew A; Ferguson, Liam; Jiménez-Díaz, María Belén; Jumani, Rajiv S; Lorimer, Donald D; Love, Melissa S; Maher, Steven; Matthews, Holly; McNamara, Case W; Miller, Peter; O'Neill, Sandra; Ojo, Kayode K; Osuna-Cabello, Maria; Pinto, Erika; Post, John; Riley, Jennifer; Rottmann, Matthias; Sanz, Laura M; Scullion, Paul; Sharma, Arvind; Shepherd, Sharon M; Shishikura, Yoko; Simeons, Frederick RC; Stebbins, Erin E; Stojanovski, Laste; Straschil, Ursula; Tamaki, Fabio K; Tamjar, Jevgenia; Torrie, Leah S; Vantaux, Amélie; Witkowski, Benoît; Wittlin, Sergio; Yogavel, Manickam; Zuccotto, Fabio; Angulo-Barturen, Iñigo; Sinden, Robert; Baum, Jake; Gamo, Francisco-Javier; Mäser, Pascal; Kyle, Dennis E; Winzeler, Elizabeth A; Myler, Peter J; Wyatt, Paul G; Floyd, David; Matthews, David; Sharma, Amit; Striepen, Boris; Huston, Christopher D; Gray, David W; Fairlamb, Alan H; Pisliakov, Andrei V; Walpole, Chris; Read, Kevin D; Van Voorhis, Wesley C; Gilbert, Ian H; (2019) Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis. Proceedings of the National Academy of Sciences of the United States of America, 116 (14). pp. 7015-7020. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1814685116
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Bradley, John; Soumaré, Harouna M; Mahamar, Almahamoudou; Diawara, Halimatou; Roh, Michelle; Delves, Michael; Drakeley, Chris; Churcher, Thomas S; Dicko, Alassane; Gosling, Roly; +1 more... Bousema, Teun; (2019) Transmission-blocking Effects of Primaquine and Methylene Blue Suggest Plasmodium falciparum Gametocyte Sterilization Rather Than Effects on Sex Ratio. Clinical Infectious Diseases, 69 (8). pp. 1436-1439. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciz134
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Children of Eden Primary School; Straschil, Ursula; Witmer, Kathrin; Delves, Michael J; Marks, Stephen D; Baum, Jake; (2019) Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials. Archives of disease in childhood, 104 (12). pp. 1138-1142. ISSN 0003-9888 DOI: https://doi.org/10.1136/archdischild-2019-317590
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Delves, Michael; Lafuente-Monasterio, M Jose; Upton, Leanna; Ruecker, Andrea; Leroy, Didier; Gamo, Francisco-Javier; Sinden, Robert; (2019) Fueling Open Innovation for Malaria Transmission-Blocking Drugs: Hundreds of Molecules Targeting Early Parasite Mosquito Stages. Frontiers in Microbiology, 10. DOI: https://doi.org/10.3389/fmicb.2019.02134
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Norcross, Neil R; Wilson, Caroline; Baragaña, Beatriz; Hallyburton, Irene; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Fletcher, Daniel; Sinden, Robert; Delves, Michael; +18 more... Ruecker, Andrea; Duffy, Sandra; Meister, Stephan; Antonova-Koch, Yevgeniya; Crespo, Benigno; de Cózar, Cristina; Sanz, Laura M; Gamo, Francisco Javier; Avery, Vicky M; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Winzeler, Elizabeth A; Waterson, David; Campbell, Simon F; Willis, Paul A; Read, Kevin D; Gilbert, Ian H; (2019) Substituted Aminoacetamides as Novel Leads for Malaria Treatment. ChemMedChem, 14 (14). pp. 1329-1335. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.201900329
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Rueda-Zubiaurre, Ainoa; Yahiya, Sabrina; Fischer, Oliver J; Hu, Xiaojun; Saunders, Charlie N; Sharma, Sachi; Straschil, Ursula; Shen, Junting; Tate, Edward W; Delves, Michael J; +3 more... Baum, Jake; Barnard, Anna; Fuchter, Matthew J; (2019) Structure-Activity Relationship Studies of a Novel Class of Transmission Blocking Antimalarials Targeting Male Gametes. Journal of medicinal chemistry, 63 (5). pp. 2240-2262. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.9b00898
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Yahiya, Sabrina; Rueda-Zubiaurre, Ainoa; Delves, Michael J; Fuchter, Matthew J; Baum, Jake; (2019) The antimalarial screening landscape-looking beyond the asexual blood stage. Current Opinion in Chemical Biology, 50. pp. 1-9. ISSN 1367-5931 DOI: https://doi.org/10.1016/j.cbpa.2019.01.029
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Zeeshan, Mohammad; Ferguson, David Jp; Abel, Steven; Burrrell, Alana; Rea, Edward; Brady, Declan; Daniel, Emilie; Delves, Michael; Vaughan, Sue; Holder, Anthony A; +3 more... Le Roch, Karine G; Moores, Carolyn A; Tewari, Rita; (2019) Kinesin-8B controls basal body function and flagellum formation and is key to malaria transmission. Life science alliance, 2 (4). e201900488-e201900488. ISSN 2575-1077 DOI: https://doi.org/10.26508/lsa.201900488
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2018

Delves, MJ; Angrisano, F; Blagborough, AM; (2018) Antimalarial Transmission-Blocking Interventions: Past, Present, and Future. Trends in parasitology, 34 (9). pp. 735-746. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2018.07.001
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Delves, Michael J; Miguel-Blanco, Celia; Matthews, Holly; Molina, Irene; Ruecker, Andrea; Yahiya, Sabrina; Straschil, Ursula; Abraham, Matthew; León, María Luisa; Fischer, Oliver J; +11 more... Rueda-Zubiaurre, Ainoa; Brandt, Jochen R; Cortés, Álvaro; Barnard, Anna; Fuchter, Matthew J; Calderón, Félix; Winzeler, Elizabeth A; Sinden, Robert E; Herreros, Esperanza; Gamo, Francisco J; Baum, Jake; (2018) A high throughput screen for next-generation leads targeting malaria parasite transmission. NATURE COMMUNICATIONS, 9 (1). 3805-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-018-05777-2
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Malpartida-Cardenas, Kenny; Rodriguez-Manzano, Jesus; Yu, Ling-Shan; Delves, Michael J; Nguon, Chea; Chotivanich, Kesinee; Baum, Jake; Georgiou, Pantelis; (2018) Allele-Specific Isothermal Amplification Method Using Unmodified Self-Stabilizing Competitive Primers. ANALYTICAL CHEMISTRY, 90 (20). pp. 11972-11980. ISSN 0003-2700 DOI: https://doi.org/10.1021/acs.analchem.8b02416
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Martí Coma-Cros, Elisabet; Biosca, Arnau; Marques, Joana; Carol, Laura; Urbán, Patricia; Berenguer, Diana; Riera, Maria Cristina; Delves, Michael; Sinden, Robert E; Valle-Delgado, Juan José; +9 more... Spanos, Lefteris; Siden-Kiamos, Inga; Pérez, Paula; Paaijmans, Krijn; Rottmann, Matthias; Manfredi, Amedea; Ferruti, Paolo; Ranucci, Elisabetta; Fernàndez-Busquets, Xavier; (2018) Polyamidoamine Nanoparticles for the Oral Administration of Antimalarial Drugs. Pharmaceutics, 10 (4). p. 225. DOI: https://doi.org/10.3390/pharmaceutics10040225
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Witmer, Kathrin; Sherrard-Smith, Ellie; Straschil, Ursula; Tunnicliff, Mark; Baum, Jake; Delves, Michael; (2018) An inexpensive open source 3D-printed membrane feeder for human malaria transmission studies. Malaria journal, 17 (1). 282-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-018-2436-9
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2017

Leven, Michael; Knaab, Tanja C; Held, Jana; Duffy, Sandra; Meister, Stephan; Fischli, Christoph; Meitzner, Diane; Lehmann, Ursula; Lungerich, Beate; Kuna, Krystina; +8 more... Stahlke, Petra; Delves, Michael J; Buchholz, Mirko; Winzeler, Elizabeth A; Avery, Vicky M; Mordmüller, Benjamin; Wittlin, Sergio; Kurz, Thomas; (2017) 3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally. Journal of medicinal chemistry, 60 (14). pp. 6036-6044. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.7b00140 Full text not available from this repository.

Miguel-Blanco, Celia; Molina, Irene; Bardera, Ana I; Díaz, Beatriz; de Las Heras, Laura; Lozano, Sonia; González, Carolina; Rodrigues, Janneth; Delves, Michael J; Ruecker, Andrea; +7 more... Colmenarejo, Gonzalo; Viera, Sara; Martínez-Martínez, María S; Fernández, Esther; Baum, Jake; Sinden, Robert E; Herreros, Esperanza; (2017) Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen. Nature communications, 8 (1). 15160-. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms15160
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O'Neill, Paul M; Amewu, Richard K; Charman, Susan A; Sabbani, Sunil; Gnädig, Nina F; Straimer, Judith; Fidock, David A; Shore, Emma R; Roberts, Natalie L; Wong, Michael H-L; +38 more... Hong, W David; Pidathala, Chandrakala; Riley, Chris; Murphy, Ben; Aljayyoussi, Ghaith; Gamo, Francisco Javier; Sanz, Laura; Rodrigues, Janneth; Cortes, Carolina Gonzalez; Herreros, Esperanza; Angulo-Barturén, Iñigo; Jiménez-Díaz, María Belén; Bazaga, Santiago Ferrer; Martínez-Martínez, María Santos; Campo, Brice; Sharma, Raman; Ryan, Eileen; Shackleford, David M; Campbell, Simon; Smith, Dennis A; Wirjanata, Grennady; Noviyanti, Rintis; Price, Ric N; Marfurt, Jutta; Palmer, Michael J; Copple, Ian M; Mercer, Amy E; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Siegl, Peter; Davies, Jill; Rochford, Rosemary; Kocken, Clemens HM; Zeeman, Anne-Marie; Nixon, Gemma L; Biagini, Giancarlo A; Ward, Stephen A; (2017) A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance. Nature communications, 8 (1). 15159-. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms15159
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Vanaerschot, Manu; Lucantoni, Leonardo; Li, Tao; Combrinck, Jill M; Ruecker, Andrea; Kumar, TR Santha; Rubiano, Kelly; Ferreira, Pedro E; Siciliano, Giulia; Gulati, Sonia; +16 more... Henrich, Philipp P; Ng, Caroline L; Murithi, James M; Corey, Victoria C; Duffy, Sandra; Lieberman, Ori J; Veiga, M Isabel; Sinden, Robert E; Alano, Pietro; Delves, Michael J; Lee Sim, Kim; Winzeler, Elizabeth A; Egan, Timothy J; Hoffman, Stephen L; Avery, Vicky M; Fidock, David A; (2017) Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity. Nature microbiology, 2 (10). pp. 1403-1414. ISSN 2058-5276 DOI: https://doi.org/10.1038/s41564-017-0007-4 Full text not available from this repository.

2016

Baragaña, Beatriz; Norcross, Neil R; Wilson, Caroline; Porzelle, Achim; Hallyburton, Irene; Grimaldi, Raffaella; Osuna-Cabello, Maria; Norval, Suzanne; Riley, Jennifer; Stojanovski, Laste; +17 more... Simeons, Frederick RC; Wyatt, Paul G; Delves, Michael J; Meister, Stephan; Duffy, Sandra; Avery, Vicky M; Winzeler, Elizabeth A; Sinden, Robert E; Wittlin, Sergio; Frearson, Julie A; Gray, David W; Fairlamb, Alan H; Waterson, David; Campbell, Simon F; Willis, Paul; Read, Kevin D; Gilbert, Ian H; (2016) Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy. Journal of medicinal chemistry, 59 (21). pp. 9672-9685. ISSN 0022-2623 DOI: https://doi.org/10.1021/acs.jmedchem.6b00723
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Delves, Michael J; Straschil, Ursula; Ruecker, Andrea; Miguel-Blanco, Celia; Marques, Sara; Dufour, Alexandre C; Baum, Jake; Sinden, Robert E; (2016) Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions. Nature protocols, 11 (9). pp. 1668-1680. ISSN 1754-2189 DOI: https://doi.org/10.1038/nprot.2016.096 Full text not available from this repository.

Le Bihan, Amélie; de Kanter, Ruben; Angulo-Barturen, Iñigo; Binkert, Christoph; Boss, Christoph; Brun, Reto; Brunner, Ralf; Buchmann, Stephan; Burrows, Jeremy; Dechering, Koen J; +30 more... Delves, Michael; Ewerling, Sonja; Ferrer, Santiago; Fischli, Christoph; Gamo-Benito, Francisco Javier; Gnädig, Nina F; Heidmann, Bibia; Jiménez-Díaz, María Belén; Leroy, Didier; Martínez, Maria Santos; Meyer, Solange; Moehrle, Joerg J; Ng, Caroline L; Noviyanti, Rintis; Ruecker, Andrea; Sanz, Laura María; Sauerwein, Robert W; Scheurer, Christian; Schleiferboeck, Sarah; Sinden, Robert; Snyder, Christopher; Straimer, Judith; Wirjanata, Grennady; Marfurt, Jutta; Price, Ric N; Weller, Thomas; Fischli, Walter; Fidock, David A; Clozel, Martine; Wittlin, Sergio; (2016) Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling. PLoS medicine, 13 (10). e1002138-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1002138
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Marques, Joana; Valle-Delgado, Juan José; Urbán, Patricia; Baró, Elisabet; Prohens, Rafel; Mayor, Alfredo; Cisteró, Pau; Delves, Michael; Sinden, Robert E; Grandfils, Christian; +3 more... de Paz, José L; García-Salcedo, José A; Fernàndez-Busquets, Xavier; (2016) Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery. Nanomedicine, 13 (2). pp. 515-525. ISSN 1549-9634 DOI: https://doi.org/10.1016/j.nano.2016.09.010
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Paquet, Tanya; Le Manach, Claire; Cabrera, Diego González; Younis, Yassir; Henrich, Philipp P; Abraham, Tara S; Lee, Marcus CS; Basak, Rajshekhar; Ghidelli-Disse, Sonja; Lafuente-Monasterio, María José; +43 more... Bantscheff, Marcus; Ruecker, Andrea; Blagborough, Andrew M; Zakutansky, Sara E; Zeeman, Anne-Marie; White, Karen L; Shackleford, David M; Mannila, Janne; Morizzi, Julia; Scheurer, Christian; Angulo-Barturen, Iñigo; Martínez, María Santos; Ferrer, Santiago; Sanz, Laura María; Gamo, Francisco Javier; Reader, Janette; Botha, Mariette; Dechering, Koen J; Sauerwein, Robert W; Tungtaeng, Anchalee; Vanachayangkul, Pattaraporn; Lim, Chek Shik; Burrows, Jeremy; Witty, Michael J; Marsh, Kennan C; Bodenreider, Christophe; Rochford, Rosemary; Solapure, Suresh M; Jiménez-Díaz, María Belén; Wittlin, Sergio; Charman, Susan A; Donini, Cristina; Campo, Brice; Birkholtz, Lyn-Marie; Hanson, Kirsten K; Drewes, Gerard; Kocken, Clemens HM; Delves, Michael J; Leroy, Didier; Fidock, David A; Waterson, David; Street, Leslie J; Chibale, Kelly; (2016) Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase. Science translational medicine, 9 (387). eaad9735-eaad9735. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aad9735 Full text not available from this repository.

Pastrana-Mena, Rebecca; Mathias, Derrick K; Delves, Michael; Rajaram, Krithika; King, Jonas G; Yee, Rebecca; Trucchi, Beatrice; Verotta, Luisella; Dinglasan, Rhoel R; (2016) A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut. ACS chemical biology, 11 (12). pp. 3461-3472. ISSN 1554-8929 DOI: https://doi.org/10.1021/acschembio.6b00902 Full text not available from this repository.

Van Voorhis, Wesley C; Adams, John H; Adelfio, Roberto; Ahyong, Vida; Akabas, Myles H; Alano, Pietro; Alday, Aintzane; Alemán Resto, Yesmalie; Alsibaee, Aishah; Alzualde, Ainhoa; +177 more... Andrews, Katherine T; Avery, Simon V; Avery, Vicky M; Ayong, Lawrence; Baker, Mark; Baker, Stephen; Ben Mamoun, Choukri; Bhatia, Sangeeta; Bickle, Quentin; Bounaadja, Lotfi; Bowling, Tana; Bosch, Jürgen; Boucher, Lauren E; Boyom, Fabrice F; Brea, Jose; Brennan, Marian; Burton, Audrey; Caffrey, Conor R; Camarda, Grazia; Carrasquilla, Manuela; Carter, Dee; Belen Cassera, Maria; Chih-Chien Cheng, Ken; Chindaudomsate, Worathad; Chubb, Anthony; Colon, Beatrice L; Colón-López, Daisy D; Corbett, Yolanda; Crowther, Gregory J; Cowan, Noemi; D'Alessandro, Sarah; Le Dang, Na; Delves, Michael; DeRisi, Joseph L; Du, Alan Y; Duffy, Sandra; Abd El-Salam El-Sayed, Shimaa; Ferdig, Michael T; Fernández Robledo, José A; Fidock, David A; Florent, Isabelle; Fokou, Patrick VT; Galstian, Ani; Gamo, Francisco Javier; Gokool, Suzanne; Gold, Ben; Golub, Todd; Goldgof, Gregory M; Guha, Rajarshi; Guiguemde, W Armand; Gural, Nil; Guy, R Kiplin; Hansen, Michael AE; Hanson, Kirsten K; Hemphill, Andrew; Hooft van Huijsduijnen, Rob; Horii, Takaaki; Horrocks, Paul; Hughes, Tyler B; Huston, Christopher; Igarashi, Ikuo; Ingram-Sieber, Katrin; Itoe, Maurice A; Jadhav, Ajit; Naranuntarat Jensen, Amornrat; Jensen, Laran T; Jiang, Rays HY; Kaiser, Annette; Keiser, Jennifer; Ketas, Thomas; Kicka, Sebastien; Kim, Sunyoung; Kirk, Kiaran; Kumar, Vidya P; Kyle, Dennis E; Lafuente, Maria Jose; Landfear, Scott; Lee, Nathan; Lee, Sukjun; Lehane, Adele M; Li, Fengwu; Little, David; Liu, Liqiong; Llinás, Manuel; Loza, Maria I; Lubar, Aristea; Lucantoni, Leonardo; Lucet, Isabelle; Maes, Louis; Mancama, Dalu; Mansour, Nuha R; March, Sandra; McGowan, Sheena; Medina Vera, Iset; Meister, Stephan; Mercer, Luke; Mestres, Jordi; Mfopa, Alvine N; Misra, Raj N; Moon, Seunghyun; Moore, John P; Morais Rodrigues da Costa, Francielly; Müller, Joachim; Muriana, Arantza; Nakazawa Hewitt, Stephen; Nare, Bakela; Nathan, Carl; Narraidoo, Nathalie; Nawaratna, Sujeevi; Ojo, Kayode K; Ortiz, Diana; Panic, Gordana; Papadatos, George; Parapini, Silvia; Patra, Kailash; Pham, Ngoc; Prats, Sarah; Plouffe, David M; Poulsen, Sally-Ann; Pradhan, Anupam; Quevedo, Celia; Quinn, Ronald J; Rice, Christopher A; Abdo Rizk, Mohamed; Ruecker, Andrea; St Onge, Robert; Salgado Ferreira, Rafaela; Samra, Jasmeet; Robinett, Natalie G; Schlecht, Ulrich; Schmitt, Marjorie; Silva Villela, Filipe; Silvestrini, Francesco; Sinden, Robert; Smith, Dennis A; Soldati, Thierry; Spitzmüller, Andreas; Stamm, Serge Maximilian; Sullivan, David J; Sullivan, William; Suresh, Sundari; Suzuki, Brian M; Suzuki, Yo; Swamidass, S Joshua; Taramelli, Donatella; Tchokouaha, Lauve RY; Theron, Anjo; Thomas, David; Tonissen, Kathryn F; Townson, Simon; Tripathi, Abhai K; Trofimov, Valentin; Udenze, Kenneth O; Ullah, Imran; Vallieres, Cindy; Vigil, Edgar; Vinetz, Joseph M; Voong Vinh, Phat; Vu, Hoan; Watanabe, Nao-Aki; Weatherby, Kate; White, Pamela M; Wilks, Andrew F; Winzeler, Elizabeth A; Wojcik, Edward; Wree, Melanie; Wu, Wesley; Yokoyama, Naoaki; Zollo, Paul HA; Abla, Nada; Blasco, Benjamin; Burrows, Jeremy; Laleu, Benoît; Leroy, Didier; Spangenberg, Thomas; Wells, Timothy; Willis, Paul A; (2016) Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS pathogens, 12 (7). e1005763-. ISSN 1553-7366 DOI: https://doi.org/10.1371/journal.ppat.1005763
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Williamson, Alice E; Ylioja, Paul M; Robertson, Murray N; Antonova-Koch, Yevgeniya; Avery, Vicky; Baell, Jonathan B; Batchu, Harikrishna; Batra, Sanjay; Burrows, Jeremy N; Bhattacharyya, Soumya; +43 more... Calderon, Felix; Charman, Susan A; Clark, Julie; Crespo, Benigno; Dean, Matin; Debbert, Stefan L; Delves, Michael; Dennis, Adelaide SM; Deroose, Frederik; Duffy, Sandra; Fletcher, Sabine; Giaever, Guri; Hallyburton, Irene; Gamo, Francisco-Javier; Gebbia, Marinella; Guy, R Kiplin; Hungerford, Zoe; Kirk, Kiaran; Lafuente-Monasterio, Maria J; Lee, Anna; Meister, Stephan; Nislow, Corey; Overington, John P; Papadatos, George; Patiny, Luc; Pham, James; Ralph, Stuart A; Ruecker, Andrea; Ryan, Eileen; Southan, Christopher; Srivastava, Kumkum; Swain, Chris; Tarnowski, Matthew J; Thomson, Patrick; Turner, Peter; Wallace, Iain M; Wells, Timothy NC; White, Karen; White, Laura; Willis, Paul; Winzeler, Elizabeth A; Wittlin, Sergio; Todd, Matthew H; (2016) Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles. ACS central science, 2 (10). pp. 687-701. ISSN 2374-7943 DOI: https://doi.org/10.1021/acscentsci.6b00086
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2015

Baragaña, Beatriz; Hallyburton, Irene; Lee, Marcus CS; Norcross, Neil R; Grimaldi, Raffaella; Otto, Thomas D; Proto, William R; Blagborough, Andrew M; Meister, Stephan; Wirjanata, Grennady; +55 more... Ruecker, Andrea; Upton, Leanna M; Abraham, Tara S; Almeida, Mariana J; Pradhan, Anupam; Porzelle, Achim; Luksch, Torsten; Martínez, María Santos; Luksch, Torsten; Bolscher, Judith M; Woodland, Andrew; Norval, Suzanne; Zuccotto, Fabio; Thomas, John; Simeons, Frederick; Stojanovski, Laste; Osuna-Cabello, Maria; Brock, Paddy M; Churcher, Tom S; Sala, Katarzyna A; Zakutansky, Sara E; Jiménez-Díaz, María Belén; Sanz, Laura Maria; Riley, Jennifer; Basak, Rajshekhar; Campbell, Michael; Avery, Vicky M; Sauerwein, Robert W; Dechering, Koen J; Noviyanti, Rintis; Campo, Brice; Frearson, Julie A; Angulo-Barturen, Iñigo; Ferrer-Bazaga, Santiago; Gamo, Francisco Javier; Wyatt, Paul G; Leroy, Didier; Siegl, Peter; Delves, Michael J; Kyle, Dennis E; Wittlin, Sergio; Marfurt, Jutta; Price, Ric N; Sinden, Robert E; Winzeler, Elizabeth A; Charman, Susan A; Bebrevska, Lidiya; Gray, David W; Campbell, Simon; Fairlamb, Alan H; Willis, Paul A; Rayner, Julian C; Fidock, David A; Read, Kevin D; Gilbert, Ian H; (2015) A novel multiple-stage antimalarial agent that inhibits protein synthesis. Nature, 522 (7556). pp. 315-320. ISSN 0028-0836 DOI: https://doi.org/10.1038/nature14451
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Leba, Louis-Jérôme; Musset, Lise; Pelleau, Stéphane; Estevez, Yannick; Birer, Caroline; Briolant, Sébastien; Witkowski, Benoit; Ménard, Didier; Delves, Michael J; Legrand, Eric; +2 more... Duplais, Christophe; Popovici, Jean; (2015) Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay. Malaria journal, 14 (1). 234-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-015-0752-x
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Miguel-Blanco, Celia; Lelièvre, Joël; Delves, Michael J; Bardera, Ana I; Presa, Jesús L; López-Barragán, María José; Ruecker, Andrea; Marques, Sara; Sinden, Robert E; Herreros, Esperanza; (2015) Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation. Antimicrobial agents and chemotherapy, 59 (6). pp. 3298-3305. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.04684-14 Full text not available from this repository.

Phillips, Margaret A; Lotharius, Julie; Marsh, Kennan; White, John; Dayan, Anthony; White, Karen L; Njoroge, Jacqueline W; El Mazouni, Farah; Lao, Yanbin; Kokkonda, Sreekanth; +43 more... Tomchick, Diana R; Deng, Xiaoyi; Laird, Trevor; Bhatia, Sangeeta N; March, Sandra; Ng, Caroline L; Fidock, David A; Wittlin, Sergio; Lafuente-Monasterio, Maria; Benito, Francisco Javier Gamo; Alonso, Laura Maria Sanz; Martinez, Maria Santos; Jimenez-Diaz, Maria Belen; Bazaga, Santiago Ferrer; Angulo-Barturen, Iñigo; Haselden, John N; Louttit, James; Cui, Yi; Sridhar, Arun; Zeeman, Anna-Marie; Kocken, Clemens; Sauerwein, Robert; Dechering, Koen; Avery, Vicky M; Duffy, Sandra; Delves, Michael; Sinden, Robert; Ruecker, Andrea; Wickham, Kristina S; Rochford, Rosemary; Gahagen, Janet; Iyer, Lalitha; Riccio, Ed; Mirsalis, Jon; Bathhurst, Ian; Rueckle, Thomas; Ding, Xavier; Campo, Brice; Leroy, Didier; Rogers, M John; Rathod, Pradipsinh K; Burrows, Jeremy N; Charman, Susan A; (2015) A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria. Science translational medicine, 7 (296). 296ra111-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aaa6645 Full text not available from this repository.

2014

Kan, Andrey; Tan, Yan-Hong; Angrisano, Fiona; Hanssen, Eric; Rogers, Kelly L; Whitehead, Lachlan; Mollard, Vanessa P; Cozijnsen, Anton; Delves, Michael J; Crawford, Simon; +5 more... Sinden, Robert E; McFadden, Geoffrey I; Leckie, Christopher; Bailey, James; Baum, Jake; (2014) Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility. Cellular microbiology, 16 (5). pp. 734-750. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12283
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Lamour, Sabrina D; Straschil, Ursula; Saric, Jasmina; Delves, Michael J; (2014) Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development. Malaria journal, 13 (1). 468-. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-13-468
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Malmquist, Nicholas A; Sundriyal, Sandeep; Caron, Joachim; Chen, Patty; Witkowski, Benoit; Menard, Didier; Suwanarusk, Rossarin; Renia, Laurent; Nosten, Francois; Jiménez-Díaz, María Belén; +13 more... Angulo-Barturen, Iñigo; Santos Martínez, María; Ferrer, Santiago; Sanz, Laura M; Gamo, Francisco-Javier; Wittlin, Sergio; Duffy, Sandra; Avery, Vicky M; Ruecker, Andrea; Delves, Michael J; Sinden, Robert E; Fuchter, Matthew J; Scherf, Artur; (2014) Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans. Antimicrobial agents and chemotherapy, 59 (2). pp. 950-959. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.04419-14 Full text not available from this repository.

Marques, Sara R; Ramakrishnan, Chandra; Carzaniga, Raffaella; Blagborough, Andrew M; Delves, Michael J; Talman, Arthur M; Sinden, Robert E; (2014) An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission. Cellular microbiology, 17 (2). pp. 191-206. ISSN 1462-5814 DOI: https://doi.org/10.1111/cmi.12355
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Ruecker, A; Mathias, DK; Straschil, U; Churcher, TS; Dinglasan, RR; Leroy, D; Sinden, RE; Delves, MJ; (2014) A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs. Antimicrobial agents and chemotherapy, 58 (12). pp. 7292-7302. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.03666-14 Full text not available from this repository.

Sala, KA; Nishiura, H; Upton, LM; Zakutansky, SE; Delves, MJ; Iyori, M; Mizutani, M; Sinden, RE; Yoshida, S; Blagborough, AM; (2014) The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro. Vaccine, 33 (3). pp. 437-445. ISSN 0264-410X DOI: https://doi.org/10.1016/j.vaccine.2014.11.038 Full text not available from this repository.

Upton, LM; Brock, PM; Churcher, TS; Ghani, AC; Gething, PW; Delves, MJ; Sala, KA; Leroy, D; Sinden, RE; Blagborough, AM; (2014) Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations. Antimicrobial agents and chemotherapy, 59 (1). pp. 490-497. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.03942-14
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Vaidya, Akhil B; Morrisey, Joanne M; Zhang, Zhongsheng; Das, Sudipta; Daly, Thomas M; Otto, Thomas D; Spillman, Natalie J; Wyvratt, Matthew; Siegl, Peter; Marfurt, Jutta; +21 more... Wirjanata, Grennady; Sebayang, Boni F; Price, Ric N; Chatterjee, Arnab; Nagle, Advait; Stasiak, Marcin; Charman, Susan A; Angulo-Barturen, Iñigo; Ferrer, Santiago; Belén Jiménez-Díaz, María; Martínez, María Santos; Gamo, Francisco Javier; Avery, Vicky M; Ruecker, Andrea; Delves, Michael; Kirk, Kiaran; Berriman, Matthew; Kortagere, Sandhya; Burrows, Jeremy; Fan, Erkang; Bergman, Lawrence W; (2014) Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum. Nature communications, 5 (1). 5521-. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms6521
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White, Nicholas J; Ashley, Elizabeth A; Recht, Judith; Delves, Michael J; Ruecker, Andrea; Smithuis, Frank M; Eziefula, Alice C; Bousema, Teun; Drakeley, Chris; Chotivanich, Kesinee; +23 more... Imwong, Mallika; Pukrittayakamee, Sasithon; Prachumsri, Jetsumon; Chu, Cindy; Andolina, Chiara; Bancone, Germana; Hien, Tran T; Mayxay, Mayfong; Taylor, Walter RJ; von Seidlein, Lorenz; Price, Ric N; Barnes, Karen I; Djimdé, Abdoulaye; ter Kuile, Feiko; Gosling, Roly; Chen, Ingrid; Dhorda, Mehul J; Stepniewska, Kasia; Guérin, Philippe; Woodrow, Charles J; Dondorp, Arjen M; Day, Nicholas PJ; Nosten, Francois H; (2014) Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria. Malaria journal, 13 (1). 483-. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-13-483
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2013

Blagborough, Andrew M; Delves, Michael J; Ramakrishnan, Chandra; Lal, Kalpana; Butcher, Geoffrey; Sinden, Robert E; (2013) Assessing transmission blockade in Plasmodium spp. Methods in molecular biology (Clifton, NJ), 923. pp. 577-600. ISSN 1064-3745 DOI: https://doi.org/10.1007/978-1-62703-026-7_40 Full text not available from this repository.

Delves, Michael J; Ruecker, Andrea; Straschil, Ursula; Lelièvre, Jöel; Marques, Sara; López-Barragán, María José; Herreros, Esperanza; Sinden, Robert E; (2013) Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs. Antimicrobial agents and chemotherapy, 57 (7). pp. 3268-3274. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00325-13 Full text not available from this repository.

Nilsen, Aaron; LaCrue, Alexis N; White, Karen L; Forquer, Isaac P; Cross, Richard M; Marfurt, Jutta; Mather, Michael W; Delves, Michael J; Shackleford, David M; Saenz, Fabian E; +31 more... Morrisey, Joanne M; Steuten, Jessica; Mutka, Tina; Li, Yuexin; Wirjanata, Grennady; Ryan, Eileen; Duffy, Sandra; Kelly, Jane Xu; Sebayang, Boni F; Zeeman, Anne-Marie; Noviyanti, Rintis; Sinden, Robert E; Kocken, Clemens HM; Price, Ric N; Avery, Vicky M; Angulo-Barturen, Iñigo; Jiménez-Díaz, María Belén; Ferrer, Santiago; Herreros, Esperanza; Sanz, Laura M; Gamo, Francisco-Javier; Bathurst, Ian; Burrows, Jeremy N; Siegl, Peter; Guy, R Kiplin; Winter, Rolf W; Vaidya, Akhil B; Charman, Susan A; Kyle, Dennis E; Manetsch, Roman; Riscoe, Michael K; (2013) Quinolone-3-diarylethers: a new class of antimalarial drug. Science translational medicine, 5 (177). 177ra37-. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.3005029 Full text not available from this repository.

Ramakrishnan, Chandra; Delves, Michael J; Lal, Kalpana; Blagborough, Andrew M; Butcher, Geoffrey; Baker, Kenneth W; Sinden, Robert E; (2013) Laboratory maintenance of rodent malaria parasites. Methods in molecular biology (Clifton, NJ), 923. pp. 51-72. ISSN 1064-3745 DOI: https://doi.org/10.1007/978-1-62703-026-7_5 Full text not available from this repository.

2012

Angrisano, Fiona; Riglar, David T; Sturm, Angelika; Volz, Jennifer C; Delves, Michael J; Zuccala, Elizabeth S; Turnbull, Lynne; Dekiwadia, Chaitali; Olshina, Maya A; Marapana, Danushka S; +11 more... Wong, Wilson; Mollard, Vanessa; Bradin, Clare H; Tonkin, Christopher J; Gunning, Peter W; Ralph, Stuart A; Whitchurch, Cynthia B; Sinden, Robert E; Cowman, Alan F; McFadden, Geoffrey I; Baum, Jake; (2012) Spatial localisation of actin filaments across developmental stages of the malaria parasite. PloS one, 7 (2). e32188-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0032188
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Biagini, Giancarlo A; Fisher, Nicholas; Shone, Alison E; Mubaraki, Murad A; Srivastava, Abhishek; Hill, Alisdair; Antoine, Thomas; Warman, Ashley J; Davies, Jill; Pidathala, Chandrakala; +22 more... Amewu, Richard K; Leung, Suet C; Sharma, Raman; Gibbons, Peter; Hong, David W; Pacorel, Bénédicte; Lawrenson, Alexandre S; Charoensutthivarakul, Sitthivut; Taylor, Lee; Berger, Olivier; Mbekeani, Alison; Stocks, Paul A; Nixon, Gemma L; Chadwick, James; Hemingway, Janet; Delves, Michael J; Sinden, Robert E; Zeeman, Anne-Marie; Kocken, Clemens HM; Berry, Neil G; O'Neill, Paul M; Ward, Stephen A; (2012) Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8298-8303. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.1205651109 Full text not available from this repository.

Churcher, Thomas S; Blagborough, Andrew M; Delves, Michael; Ramakrishnan, Chandra; Kapulu, Melissa C; Williams, Andrew R; Biswas, Sumi; Da, Dari F; Cohuet, Anna; Sinden, Robert E; (2012) Measuring the blockade of malaria transmission--an analysis of the Standard Membrane Feeding Assay. International journal for parasitology, 42 (11). pp. 1037-1044. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2012.09.002 Full text not available from this repository.

Delves, Michael J; (2012) Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs. Future medicinal chemistry, 4 (18). pp. 2251-2263. ISSN 1756-8919 DOI: https://doi.org/10.4155/fmc.12.182 Full text not available from this repository.

Delves, Michael J; Ramakrishnan, Chandra; Blagborough, Andrew M; Leroy, Didier; Wells, Timothy NC; Sinden, Robert E; (2012) A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines. International journal for parasitology, 42 (11). pp. 999-1006. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2012.08.009 Full text not available from this repository.

Delves, Michael; Plouffe, David; Scheurer, Christian; Meister, Stephan; Wittlin, Sergio; Winzeler, Elizabeth A; Sinden, Robert E; Leroy, Didier; (2012) The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites. PLoS medicine, 9 (2). e1001169-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001169
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Sinden, Robert E; Blagborough, Andrew M; Churcher, Thomas; Ramakrishnan, Chandra; Biswas, Sumi; Delves, Michael J; (2012) The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium. Trends in parasitology, 28 (11). pp. 457-465. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2012.07.005 Full text not available from this repository.

2011

Angrisano, Fiona; Delves, Michael J; Sturm, Angelika; Mollard, Vanessa; McFadden, Geoffrey I; Sinden, Robert E; Baum, Jake; (2011) A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle. Molecular and biochemical parasitology, 182 (1-2). pp. 93-96. ISSN 0166-6851 DOI: https://doi.org/10.1016/j.molbiopara.2011.11.008 Full text not available from this repository.

Slavic, Ksenija; Delves, Michael J; Prudêncio, Miguel; Talman, Arthur M; Straschil, Ursula; Derbyshire, Elvira T; Xu, Zhengyao; Sinden, Robert E; Mota, Maria M; Morin, Christophe; +3 more... Tewari, Rita; Krishna, Sanjeev; Staines, Henry M; (2011) Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle. Antimicrobial agents and chemotherapy, 55 (6). pp. 2824-2830. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.01739-10 Full text not available from this repository.

2010

2008

Lal, Kalpana; Delves, Michael J; Bromley, Elizabeth; Wastling, Jonathan M; Tomley, Fiona M; Sinden, Robert E; (2008) Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. International journal for parasitology, 39 (7). pp. 755-761. ISSN 0020-7519 DOI: https://doi.org/10.1016/j.ijpara.2008.11.008 Full text not available from this repository.

This list was generated on Fri Apr 9 06:38:45 2021 BST.