Items where Author or Contributor is "Shakur, Haleema"
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Number of items: 140.
2024
Ker, Katharine;
Sentilhes, Loic;
Shakur-Still, Haleema;
Madar, Hugo;
Deneux-Tharaux, Catherine;
Saade, George;
Pacheco, Luis;
Ageron, François-Xavier;
Mansukhani, Raoul;
Balogun, Eni;
+7 more...
Brenner, Amy;
Prowse, Danielle;
Arribas, Monica;
Ahmadzia, Homa;
Chaudhri, Rizwana;
Olayemi, Oladapo;
Roberts, Ian;
(2024)
Tranexamic acid for postpartum bleeding: a systematic review and individual patient data meta-analysis.
The Lancet, 404 (10463).
pp. 1657-1667.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(24)02102-0
Ker, Katharine;
Sentilhes, Loïc;
Shakur-Still, Haleema;
Madar, Hugo;
Deneux-Tharaux, Catherine;
Saade, George;
Pacheco, Luis D;
Ageron, François-Xavier;
Mansukhani, Raoul;
Balogun, Eni;
+8 more...
Brenner, Amy;
Prowse, Danielle;
Arribas, Monica;
Ahmadzia, Homa;
Chaudhri, Rizwana;
Olayemi, Oladapo;
Roberts, Ian;
Anti-fibrinolytics Trialists Collaborators Obstetric Group;
(2024)
Tranexamic acid for postpartum bleeding: a systematic review and individual patient data meta-analysis of randomised controlled trials.
Lancet, 404 (10463).
pp. 1657-1667.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(24)02102-0
Mansukhani, Raoul;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Frimley, Lauren;
Faizah Jamaluddin, Sabariah;
Jooma, Rashid;
Shakur-Still, Haleema;
Shokunbi, Temitayo;
Roberts, Ian;
(2024)
Effect of early tranexamic acid treatment on fatigue in patients with mild traumatic brain injury: data from the CRASH-3 clinical trial.
Wellcome open research, 6.
p. 346.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.17421.3
![[img]](/style/images/fileicons/text.png)
2023
Anti-fibrinolytics Trialists Collaborators – Obstetric Trialists;
Ker, Katharine;
Shakur-Still, Haleema;
Sentilhes, Loïc;
Pacheco, Luis D;
Saade, George;
Deneux-Tharaux, Catherine;
Brenner, Amy;
Mansukhani, Raoul;
Ageron, François-Xavier;
+4 more...
Prowse, Danielle;
Chaudhri, Rizwana;
Olayemi, Oladapo;
Roberts, Ian;
(2023)
Tranexamic acid for the prevention of postpartum bleeding: Protocol for a systematic review and individual patient data meta-analysis.
Gates open research, 7.
3-.
ISSN 2572-4754
DOI: https://doi.org/10.12688/gatesopenres.13747.2
Brenner, A;
(2023)
Outcome measures in clinical trials of tranexamic acid for bleeding.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04670856
Brenner, Amy;
Shakur-Still, Haleema;
Chaudhri, Rizwana;
Muganyizi, Projestine;
Olayemi, Oladapo;
Arribas, Monica;
Kayani, Aasia;
Javid, Kiran;
Bello, Adenike;
Roberts, Ian;
+1 more...
I’M WOMAN Trial Collaborative Group;
(2023)
Tranexamic acid by the intramuscular or intravenous route for the prevention of postpartum haemorrhage in women at increased risk: a randomised placebo-controlled trial (I'M WOMAN).
Trials, 24 (1).
782-.
DOI: https://doi.org/10.1186/s13063-023-07687-1
Ker, Katharine;
Mansukhani, Raoul;
Shakur-Still, Haleema;
Arribas, Monica;
Beaumont, Danielle;
Roberts, Ian;
(2023)
Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients.
BMJ Open, 13 (2).
e059982-.
DOI: https://doi.org/10.1136/bmjopen-2021-059982
Shakur-Still, Haleema;
Roberts, Ian;
Grassin-Delyle, Stanislas;
Chaudhri, Rizwana;
Geer, Amber;
Arribas, Monica;
Lamy, Elodie;
Mansukhani, Raoul;
Lubeya, Mwansa Ketty;
Javaid, Kiran;
+11 more...
Kayani, Aasia;
Israr, Naila;
Mazhar, Syeda Batool;
Urien, Saïk;
Bouazza, Naïm;
Foissac, Frantz;
Prowse, Danielle;
Carrington, Laura;
Barrow, Collette;
Onandia, Julio Gil;
Balogun, Eni;
(2023)
Alternative routes for tranexamic acid treatment in obstetric bleeding (WOMAN-PharmacoTXA trial): a randomised trial and pharmacological study in caesarean section births.
BJOG : an international journal of obstetrics and gynaecology, 130 (10).
pp. 1177-1186.
ISSN 1470-0328
DOI: https://doi.org/10.1111/1471-0528.17455
2022
Ageron, Francois-Xavier;
Shakur-Still, Haleema;
Roberts, Ian;
(2022)
Effects of tranexamic acid treatment in severely and non-severely injured trauma patients.
Transfusion, 62 Sup (Suppl ).
S151-S157.
ISSN 0041-1132
DOI: https://doi.org/10.1111/trf.16954
Bazeer, Nuha;
Miners, Alec;
Roberts, Ian;
Shakur-Still, Haleema;
Jairath, Vipul;
Williams, Jack;
(2022)
Economic evaluation of tranexamic acid for the treatment of acute gastrointestinal bleeding: a cost-effectiveness analysis using data from the HALT-IT randomised controlled trial.
BMJ Open, 12 (7).
e060505-e060505.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2021-060505
Brenner, Amy;
Roberts, Ian;
Balogun, Eni;
Bello, Folasade Adenike;
Chaudhri, Rizwana;
Fleming, Charlotte;
Javaid, Kiran;
Kayani, Aasia;
Lubeya, Mwansa Ketty;
Mansukhani, Raoul;
+4 more...
Olayemi, Oladapo;
Prowse, Danielle;
Vwalika, Bellington;
Shakur-Still, Haleema;
(2022)
Postpartum haemorrhage in anaemic women: assessing outcome measures for clinical trials.
Trials, 23 (1).
220-.
DOI: https://doi.org/10.1186/s13063-022-06140-z
Grassin-Delyle, Stanislas;
Semeraro, Michaela;
Lamy, Elodie;
Urien, Saïk;
Runge, Iléana;
Foissac, Frantz;
Bouazza, Naim;
Treluyer, Jean-Marc;
Arribas, Monica;
Roberts, Ian;
+1 more...
Shakur-Still, Haleema;
(2022)
Pharmacokinetics of tranexamic acid after intravenous, intramuscular, and oral routes: a prospective, randomised, crossover trial in healthy volunteers.
British Journal of Anaesthesia, 128 (3).
pp. 465-472.
ISSN 0007-0912
DOI: https://doi.org/10.1016/j.bja.2021.10.054
Nutbeam, Tim;
Roberts, Ian;
Weekes, Lauren;
Shakur-Still, Haleema;
Brenner, Amy;
Ageron, Francois-Xavier;
(2022)
Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2 and CRASH-3) trials and UK trauma registry (Trauma and Audit Research Network) data.
British Journal of Anaesthesia, 129 (2).
pp. 191-199.
ISSN 0007-0912
DOI: https://doi.org/10.1016/j.bja.2022.03.032
Roberts, Ian;
Brenner, Amy;
Shakur-Still, Haleema;
(2022)
Tranexamic acid for bleeding: Much more than a treatment for postpartum hemorrhage.
American Journal of Obstetrics & Gynecology, 5 (2S).
100722-.
ISSN 2589-9333
DOI: https://doi.org/10.1016/j.ajogmf.2022.100722
Shakur-Still, Haleema;
Grassin-Delyle, Stanislas;
Muhunthan, Kopalasuntharam;
Ahmadzia, Homa K;
Faraoni, David;
Arribas, Monica;
Roberts, Ian;
(2022)
Alternative routes to intravenous tranexamic acid for postpartum hemorrhage: A systematic search and narrative review.
International journal of gynecology & obstetrics, 158 Su (Suppl ).
pp. 40-45.
ISSN 0020-7292
DOI: https://doi.org/10.1002/ijgo.14201
Williams, Jack;
Ker, Katharine;
Roberts, Ian;
Shakur-Still, Haleema;
Miners, Alec;
(2022)
A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury.
Trials, 23 (1).
370-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-022-06244-6
Item availability may be restricted.
Williams, Jack;
Ker, Katharine;
Roberts, Ian;
Shakur-Still, Haleema;
Miners, Alec;
(2022)
A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury.
Trials, 23 (1).
370-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-022-06244-6
Item availability may be restricted.
![[img]](/style/images/fileicons/application_pdf.png)
2021
Ageron, F-X D;
(2021)
Tranexamic acid in trauma care : who should be treated, when and where?
PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04662122
Arribas, Monica;
Roberts, Ian;
Chaudhri, Rizwana;
Geer, Amber;
Prowse, Danielle;
Lubeya, Mwansa Ketty;
Kayani, Aasia;
Javaid, Kiran;
Grassin-Delyle, Stanislas;
Shakur-Still, Haleema;
(2021)
WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section.
Wellcome open research, 6.
157-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.16884.1
Grassin-Delyle, Stanislas;
Lamy, Elodie;
Semeraro, Michaela;
Runge, Iléana;
Treluyer, Jean-Marc;
Mansukhani, Raoul;
Arribas, Monica;
Roberts, Ian;
Shakur-Still, Haleema;
(2021)
Clinical Validation of a Volumetric Absorptive Micro-Sampling Device for Pharmacokinetic Studies With Tranexamic Acid.
Frontiers in pharmacology, 12.
764379-.
ISSN 1663-9812
DOI: https://doi.org/10.3389/fphar.2021.764379
Herrett, Emily;
Williamson, Elizabeth;
Brack, Kieran;
Beaumont, Danielle;
Perkins, Alexander;
Thayne, Andrew;
Shakur-Still, Haleema;
Roberts, Ian;
Prowse, Danielle;
Goldacre, Ben;
+11 more...
van Staa, Tjeerd;
MacDonald, Thomas M;
Armitage, Jane;
Wimborne, Jon;
Melrose, Paula;
Singh, Jayshireen;
Brooks, Lucy;
Moore, Michael;
Hoffman, Maurice;
Smeeth, Liam;
StatinWISE Trial Group;
(2021)
Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials.
British Medical Journal, 372.
n135-.
ISSN 1756-1833
DOI: https://doi.org/10.1136/bmj.n135
Herrett, Emily;
Williamson, Elizabeth;
Brack, Kieran;
Beaumont, Danielle;
Perkins, Alexander;
Thayne, Andrew;
Shakur-Still, Haleema;
Roberts, Ian;
Prowse, Danielle;
Goldacre, Ben;
+10 more...
van Staa, Tjeerd;
MacDonald, Thomas M;
Armitage, Jane;
Wimborne, Jon;
Melrose, Paula;
Singh, Jayshireen;
Brooks, Lucy;
Moore, Michael;
Hoffman, Maurice;
Smeeth, Liam;
(2021)
Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials.
BMJ, 372.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.n135
Herrett, Emily;
Williamson, Elizabeth;
Brack, Kieran;
Perkins, Alexander;
Thayne, Andrew;
Shakur-Still, Haleema;
Roberts, Ian;
Prowse, Danielle;
Beaumont, Danielle;
Jamal, Zahra;
+7 more...
Goldacre, Ben;
van Staa, Tjeerd;
MacDonald, Thomas M;
Armitage, Jane;
Moore, Michael;
Hoffman, Maurice;
Smeeth, Liam;
(2021)
The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs.
Health technology assessment (Winchester, England), 25 (16).
pp. 1-62.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta25160
Kane, Zoe;
Picetti, Roberto;
Wilby, Alison;
Standing, Joseph F;
Grassin-Delyle, Stanislas;
Roberts, Ian;
Shakur-Still, Haleema;
(2021)
Physiologically based modelling of tranexamic acid pharmacokinetics following intravenous, intramuscular, sub-cutaneous and oral administration in healthy volunteers.
European Journal of Pharmaceutical Sciences, 164.
105893-.
ISSN 0928-0987
DOI: https://doi.org/10.1016/j.ejps.2021.105893
Mansukhani, Raoul;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Frimley, Lauren;
Faizah Jamaluddin, Sabariah;
Jooma, Rashid;
Shakur-Still, Haleema;
Shokunbi, Temitayo;
Roberts, Ian;
(2021)
Effect of early tranexamic acid treatment on fatigue in patients with mild traumatic brain injury: data from the CRASH-3 clinical trial.
Wellcome Open Research, 6.
p. 346.
DOI: https://doi.org/10.12688/wellcomeopenres.17421.1
Miller, Lori;
Chaudhri, Shahana;
Beaumont, Danielle;
Kayani, Aasia;
Javid, Kiran;
Chaudhri, Rizwana;
Edwards, Phil;
Brenner, Amy;
Roberts, Ian;
Shakur-Still, Haleema;
(2021)
Development of a patient reported outcome questionnaire to measure the impact of postpartum blood loss in women with moderate and severe anaemia: A study using a multi-faceted approach.
Wellcome Open Research, 4.
p. 85.
DOI: https://doi.org/10.12688/wellcomeopenres.15245.1
Miller, Lori;
Chaudhri, Shahana;
Beaumont, Danielle;
Kayani, Aasia;
Javid, Kiran;
Chaudhri, Rizwana;
Edwards, Phil;
Brenner, Amy;
Roberts, Ian;
Shakur-Still, Haleema;
(2021)
Development of a patient reported outcome questionnaire to measure the impact of postpartum blood loss in women with moderate and severe anaemia: A study using a multi-faceted approach.
Wellcome Open Research, 4.
p. 85.
DOI: https://doi.org/10.12688/wellcomeopenres.15245.2
Roberts, Ian;
Brenner, Amy;
Shakur-Still, Haleema;
(2021)
Tranexamic Acid Treatment for Trauma Victims.
Seminars in Thrombosis and Hemostasis, 47 (5).
pp. 520-526.
ISSN 0094-6176
DOI: https://doi.org/10.1055/s-0041-1725097
Roberts, Ian;
Shakur-Still, Haleema;
Aeron-Thomas, Amy;
Beaumont, Danielle;
Belli, Antonio;
Brenner, Amy;
Cargill, Madeleine;
Chaudhri, Rizwana;
Douglas, Nicolas;
Frimley, Lauren;
+10 more...
Gilliam, Catherine;
Geer, Amber;
Jamal, Zahra;
Jooma, Rashid;
Mansukhani, Raoul;
Miners, Alec;
Pott, Jason;
Prowse, Danielle;
Shokunbi, Temitayo;
Williams, Jack;
(2021)
Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT.
Health technology assessment (Winchester, England), 25 (26).
pp. 1-76.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta25260
Roberts, Ian;
Shakur-Still, Haleema;
Afolabi, Adefemi;
Akere, Adegboyega;
Arribas, Monica;
Austin, Emma;
Bal, Kiran;
Bazeer, Nuha;
Beaumont, Danielle;
Brenner, Amy;
+20 more...
Carrington, Laura;
Chaudhri, Rizwana;
Coats, Timothy;
Gilmore, Ian;
Halligan, Kenneth;
Hussain, Irshad;
Jairath, Vipul;
Javaid, Kiran;
Kayani, Aasia;
Lisman, Ton;
Mansukhani, Raoul;
Miners, Alec;
Mutti, Muttiullah;
Nadeem, Muhammad Arif;
Pollok, Richard;
Prowse, Danielle;
Simmons, Jonathan;
Stanworth, Simon;
Veitch, Andrew;
Williams, Jack;
(2021)
A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT.
Health technology assessment (Winchester, England), 25 (58).
pp. 1-86.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta25580
2020
Ageron, Francois-Xavier;
Gayet-Ageron, Angele;
Ker, Katharine;
Coats, Timothy J;
Shakur-Still, Haleema;
Roberts, Ian;
Antifibrinolytics Trials Collaboration;
(2020)
Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients.
BRITISH JOURNAL OF ANAESTHESIA, 124 (6).
pp. 676-683.
ISSN 0007-0912
DOI: https://doi.org/10.1016/j.bja.2020.01.020
Brenner, Amy;
Belli, Antonio;
Chaudhri, Rizwana;
Coats, Timothy;
Frimley, Lauren;
Jamaluddin, Sabariah Faizah;
Jooma, Rashid;
Mansukhani, Raoul;
Sandercock, Peter;
Shakur-Still, Haleema;
+3 more...
Shokunbi, Temitayo;
Roberts, Ian;
CRASH-3 trial collaborators;
(2020)
Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial.
CRITICAL CARE, 24 (1).
560-.
ISSN 1364-8535
DOI: https://doi.org/10.1186/s13054-020-03243-4
Grassin-Delyle, Stanislas;
Shakur-Still, Haleema;
Picetti, Roberto;
Frimley, Lauren;
Jarman, Heather;
Davenport, Ross;
McGuinness, William;
Moss, Phil;
Pott, Jason;
Tai, Nigel;
+7 more...
Lamy, Elodie;
Urien, Saïk;
Prowse, Danielle;
Thayne, Andrew;
Gilliam, Catherine;
Pynn, Harvey;
Roberts, Ian;
(2020)
Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial.
British journal of anaesthesia, 126 (1).
pp. 201-209.
ISSN 0007-0912
DOI: https://doi.org/10.1016/j.bja.2020.07.058
Hough, Amy;
Shakur-Still, Haleema;
Roberts, Ian;
Koukounari, Artemis;
Lawn, Joy E;
WOMAN Trial Collaborators;
(2020)
Stillbirths and neonatal deaths among 18 942 women with postpartum hemorrhage: Analysis of perinatal outcomes in the WOMAN trial.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (1).
ISSN 0020-7292
DOI: https://doi.org/10.1002/ijgo.13413
Kolin, David A;
Shakur-Still, Haleema;
Bello, Adenike;
Chaudhri, Rizwana;
Bates, Imelda;
Roberts, Ian;
(2020)
Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials.
PloS one, 15 (6).
e0233274-.
DOI: https://doi.org/10.1371/journal.pone.0233274
Lamy, Elodie;
Runge, Ileana;
Roberts, Ian;
Shakur-Still, Haleema;
Grassin-Delyle, Stanislas;
(2020)
Tranexamic acid quantification in human whole blood using liquid samples or volumetric absorptive microsampling devices.
Bioanalysis, 12 (12).
pp. 835-844.
ISSN 1757-6180
DOI: https://doi.org/10.4155/bio-2020-0088
Mahmood, A;
(2020)
Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a randomised trial.
PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04659849
Mahmood, Abda;
Needham, Kelly;
Shakur-Still, Haleema;
Harris, Tim;
Jamaluddin, Sabariah Faizah;
Davies, David;
Belli, Antonio;
Mohamed, Fatahul Laham;
Leech, Caroline;
Lotfi, Hamzah Mohd;
+8 more...
Moss, Phil;
Lecky, Fiona;
Hopkins, Philip;
Wong, Darin;
Boyle, Adrian;
Wilson, Mark;
Darwent, Melanie;
Roberts, Ian;
(2020)
Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients.
Emergency medicine journal : EMJ, 38 (4).
pp. 270-278.
ISSN 1472-0205
DOI: https://doi.org/10.1136/emermed-2020-210424
Mansukhani, Raoul;
Frimley, Lauren;
Shakur-Still, Haleema;
Sharples, Linda;
Roberts, Ian;
(2020)
Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results.
Trials, 21 (1).
681-.
DOI: https://doi.org/10.1186/s13063-020-04623-5
Picetti, Roberto;
Miller, Lori;
Shakur-Still, Haleema;
Pepple, Tracey;
Beaumont, Danielle;
Balogun, Eni;
Asonganyi, Etienne;
Chaudhri, Rizwana;
El-Sheikh, Mohamed;
Vwalika, Bellington;
+2 more...
Arulkumaran, Sabaratnam;
Roberts, Ian;
(2020)
The WOMAN Trial: Clinical and Contextual Factors Surrounding the Deaths of 483 Women Following Post-Partum Hemorrhage in Developing Countries.
Obstetrical & Gynecological Survey, 75 (12).
pp. 723-725.
ISSN 0029-7828
DOI: https://doi.org/10.1097/01.ogx.0000723728.09046.e3
Picetti, Roberto;
Miller, Lori;
Shakur-Still, Haleema;
Pepple, Tracey;
Beaumont, Danielle;
Balogun, Eni;
Asonganyi, Etienne;
Chaudhri, Rizwana;
El-Sheikh, Mohamed;
Vwalika, Bellington;
+3 more...
Arulkumaran, Sabaratnam;
Roberts, Ian;
WOMAN trial collaborators;
(2020)
The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries.
BMC Pregnancy and Childbirth, 20 (1).
409-.
ISSN 1471-2393
DOI: https://doi.org/10.1186/s12884-020-03091-8
Williams, Jack;
Roberts, Ian;
Shakur-Still, Haleema;
Lecky, Fiona E;
Chaudhri, Rizwana;
Miners, Alec;
(2020)
Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach.
BMJ GLOBAL HEALTH, 5 (9).
e002716-e002716.
ISSN 2059-7908
DOI: https://doi.org/10.1136/bmjgh-2020-002716
2019
Beaumont, Danielle;
Arribas, Monica;
Frimley, Lauren;
Balogun, Eni;
Roberts, Ian;
Shakur-Still, Haleema;
(2019)
Trial management: we need a cadre of high-class triallists to deliver the answers that patients need.
Trials, 20 (1).
354-.
DOI: https://doi.org/10.1186/s13063-019-3451-z
Brenner, Amy;
Afolabi, Adefemi;
Ahmad, Syed Masroor;
Arribas, Monica;
Chaudhri, Rizwana;
Coats, Timothy;
Cuzick, Jack;
Gilmore, Ian;
Hawkey, Christopher;
Jairath, Vipul;
+9 more...
Javaid, Kiran;
Kayani, Aasia;
Mutti, Muttiullah;
Nadeem, Muhammad Arif;
Shakur-Still, Haleema;
Stanworth, Simon;
Veitch, Andrew;
Roberts, Ian;
HALT-IT Trial Collaborators;
(2019)
Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Trials, 20 (1).
467-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-019-3561-7
Brenner, Amy;
Ker, Katharine;
Shakur-Still, Haleema;
Roberts, Ian;
(2019)
Tranexamic acid for post-partum haemorrhage: What, who and when.
Best Practice & Research Clinical Obstetrics & Gynaecology, 61.
pp. 66-74.
ISSN 1521-6934
DOI: https://doi.org/10.1016/j.bpobgyn.2019.04.005
Cornelissen, Laura;
Woodd, Susannah;
Shakur-Still, Haleema;
Fawole, Bukola;
Noor, Shehla;
Etuk, Saturday;
Akintan, Adesina Lawrence;
Chaudhri, Rizwana;
Roberts, Ian;
(2019)
Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage.
International journal of gynaecology and obstetrics, 146 (2).
pp. 231-237.
ISSN 0020-7292
DOI: https://doi.org/10.1002/ijgo.12860
Dallaku, Kastriot;
Shakur-Still, Haleema;
Beaumont, Danielle;
Roberts, Ian;
Huque, Sumaya;
Delius, Maria;
Holdenrieder, Stefan;
Gliozheni, Orion;
Mansmann, Ulrich;
(2019)
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial.
Wellcome open research, 4.
21-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14977.1
Dallaku, Kastriot;
Shakur-Still, Haleema;
Beaumont, Danielle;
Roberts, Ian;
Huque, Sumaya;
Delius, Maria;
Holdenrieder, Stefan;
Gliozheni, Orion;
Mansmann, Ulrich;
(2019)
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial.
Wellcome Open Research, 4.
21-.
DOI: https://doi.org/10.12688/wellcomeopenres.14977.1
Mahmood, Abda;
Roberts, Ian;
Shakur-Still, Haleema;
(2019)
A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan.
Wellcome open research, 3.
99-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14731.3
2018
Brenner, Amy;
Arribas, Monica;
Cuzick, Jack;
Jairath, Vipul;
Stanworth, Simon;
Ker, Katharine;
Shakur-Still, Haleema;
Roberts, Ian;
(2018)
Outcome measures in clinical trials of treatments for acute severe haemorrhage.
Trials, 19 (1).
533-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-018-2900-4
Brenner, Amy;
Shakur-Still, Haleema;
Chaudhri, Rizwana;
Fawole, Bukola;
Arulkumaran, Sabaratnam;
Roberts, Ian;
WOMAN Trial Collaborators;
(2018)
The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial.
BMC pregnancy and childbirth, 18 (1).
215-.
ISSN 1471-2393
DOI: https://doi.org/10.1186/s12884-018-1855-5
Hibbs, Stephen P;
Roberts, Ian;
Shakur-Still, Haleema;
Hunt, Beverley J;
(2018)
Post-partum haemorrhage and tranexamic acid: a global issue.
British journal of haematology, 180 (6).
pp. 799-807.
ISSN 0007-1048
DOI: https://doi.org/10.1111/bjh.15073
Houghton, G;
Kingdon, C;
Dower, M;
Shakur-Still, H;
Alfirevic, Z;
(2018)
What women think about consent to research at the time of an obstetric emergency: a qualitative study of the views of a cohort of World Maternal Antifibrinolytic Trial participants.
BJOG, 125 (13).
pp. 1744-1753.
ISSN 1470-0328
DOI: https://doi.org/10.1111/1471-0528.15333
Huque, Sumaya;
Roberts, Ian;
Fawole, Bukola;
Chaudhri, Rizwana;
Arulkumaran, Sabaratnam;
Shakur-Still, Haleema;
(2018)
Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial.
BMC pregnancy and childbirth, 18 (1).
186-.
ISSN 1471-2393
DOI: https://doi.org/10.1186/s12884-018-1829-7
Ker, Katharine;
Roberts, Ian;
Chaudhri, Rizwana;
Fawole, Bukola;
Beaumont, Danielle;
Balogun, Eni;
Prowse, Danielle;
Pepple, Tracey;
Javaid, Kiran;
Kayani, Aasia;
+4 more...
Arulkumaran, Sabaratnam;
Bates, Imelda;
Shakur-Still, Haleema;
WOMAN-2 trial collaborators;
(2018)
Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial.
Trials, 19 (1).
712-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-018-3081-x
Li, Bernadette;
Miners, Alec;
Shakur, Haleema;
Roberts, Ian;
WOMAN Trial Collaborators;
(2018)
Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial.
The Lancet Global health, 6 (2).
e222-e228.
ISSN 2214-109X
DOI: https://doi.org/10.1016/S2214-109X(17)30467-9
Picetti, Roberto;
Shakur-Still, Haleema;
Medcalf, Robert L;
Standing, Joseph F;
Roberts, Ian;
(2018)
What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies.
Blood coagulation & fibrinolysis, 30 (1).
pp. 1-10.
ISSN 0957-5235
DOI: https://doi.org/10.1097/MBC.0000000000000789
Roberts, Ian;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Fawole, Bukola;
Harris, Tim;
Jooma, Rashid;
Mahmood, Abda;
Shokunbi, Temitayo;
Shakur, Haleema;
(2018)
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3.
p. 86.
DOI: https://doi.org/10.12688/wellcomeopenres.14700.1
Roberts, Ian;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Fawole, Bukola;
Harris, Tim;
Jooma, Rashid;
Mahmood, Abda;
Shokunbi, Temitayo;
Shakur, Haleema;
(2018)
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3.
p. 86.
DOI: https://doi.org/10.12688/wellcomeopenres.14700.2
Roberts, Ian;
Belli, Antonio;
Brenner, Amy;
Chaudhri, Rizwana;
Fawole, Bukola;
Harris, Tim;
Jooma, Rashid;
Mahmood, Abda;
Shokunbi, Temitayo;
Shakur, Haleema;
+1 more...
CRASH-3 trial collaborators;
(2018)
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial.
Wellcome open research, 3.
86-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14700.2
Roberts, Ian;
Shakur, Haleema;
Bellomo, Rinaldo;
Bion, Julian;
Finfer, Simon;
Hunt, Beverley;
Myburgh, John;
Perner, Anders;
Reinhart, Konrad;
(2018)
Hydroxyethyl starch solutions and patient harm.
Lancet, 391 (10122).
736-.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(18)30255-1
Full text not available from this repository.
Roberts, Ian;
Shakur, Haleema;
Bellomo, Rinaldo;
Bion, Julian;
Finfer, Simon;
Hunt, Beverley;
Myburgh, John;
Perner, Anders;
Reinhart, Konrad;
(2018)
Should hydroxyethyl starch be banned? - Authors' reply.
Lancet, 392 (10142).
119-.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(18)31179-6
Full text not available from this repository.
Roberts, Ian;
Shakur, Haleema;
Fawole, Bukola;
Kuti, Modupe;
Olayemi, Oladapo;
Bello, Adenike;
Ogunbode, Olayinka;
Kotila, Taiwo;
Aimakhu, Chris O;
Olutogun, Tolulase;
+2 more...
Hunt, Beverley J;
Huque, Sumaya;
(2018)
Haematological and fibrinolytic status of Nigerian women with post-partum haemorrhage.
BMC pregnancy and childbirth, 18 (1).
143-.
ISSN 1471-2393
DOI: https://doi.org/10.1186/s12884-018-1794-1
Shakur, Haleema;
Beaumont, Danielle;
Pavord, Sue;
Gayet-Ageron, Angele;
Ker, Katharine;
Mousa, Hatem A;
(2018)
Antifibrinolytic drugs for treating primary postpartum haemorrhage.
The Cochrane database of systematic reviews, 2 (2).
CD012964-CD012964.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD012964
Shakur, Haleema;
Beaumont, Danielle;
Pavord, Sue;
Gayet-Ageron, Angele;
Ker, Katharine;
Mousa, Hatem A;
(2018)
Antifibrinolytic drugs for treating primary postpartum hemorrhage.
Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 32 (3).
pp. 203-205.
ISSN 1137-6821
DOI: https://doi.org/10.1002/14651858.CD012964
Shakur-Still, Haleema;
Roberts, Ian;
(2018)
Finding Better Ways to Prevent Postpartum Hemorrhage.
The New England journal of medicine, 379 (8).
pp. 790-792.
ISSN 0028-4793
DOI: https://doi.org/10.1056/NEJMe1808500
Shakur-Still, Haleema;
Roberts, Ian;
Fawole, Bukola;
Kuti, Modupe;
Olayemi, Oladapo O;
Bello, Adenike;
Huque, Sumaya;
Ogunbode, Olayinka;
Kotila, Taiwo;
Aimakhu, Chris;
+8 more...
Okunade, Olujide A;
Olutogun, Tolulase;
Adetayo, Cecilia O;
Dallaku, Kastriot;
Mansmann, Ulrich;
Hunt, Beverley J;
Pepple, Tracey;
Balogun, Eni;
(2018)
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial.
Wellcome open research, 3.
100-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14722.1
Shakur-Still, Haleema;
Roberts, Ian;
Fawole, Bukola;
Kuti, Modupe;
Olayemi, Oladapo;
Bello, Adenike;
Huque, Sumaya;
Ogunbode, Olayinka;
Kotila, Taiwo;
Aimakhu, Chris;
+8 more...
Okunade, Olujide;
Olutogun, Tolulase;
Adetayo, Cecilia;
Dallaku, Kastriot;
Mansmann, Ulrich;
Hunt, Beverley;
Pepple, Tracey;
Balogun, Eni;
(2018)
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial.
Wellcome Open Research, 3 (100).
14722-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.14722.1
2017
Dallaku, Kastriot;
Shakur, Haleema;
Edwards, Phil;
Beaumont, Danielle;
Roberts, Ian;
Huque, Sumaya;
Delius, Maria;
Mansmann, Ulrich;
(2017)
Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation.
Wellcome Open Research, 1.
p. 30.
DOI: https://doi.org/10.12688/wellcomeopenres.10105.1
Gayet-Ageron, Angèle;
Prieto-Merino, David;
Ker, Katharine;
Shakur, Haleema;
Ageron, François-Xavier;
Roberts, Ian;
Antifibrinolytic Trials Collaboration;
(2017)
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients.
Lancet, 391 (10116).
pp. 125-132.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(17)32455-8
Herrett, Emily;
Williamson, Elizabeth;
Beaumont, Danielle;
Prowse, Danielle;
Youssouf, Nabila;
Brack, Kieran;
Armitage, Jane;
Goldacre, Ben;
MacDonald, Thomas;
Staa, Tjeerd van;
+3 more...
Roberts, Ian;
Shakur-Still, Haleema;
Smeeth, Liam;
(2017)
Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care.
BMJ open, 7 (12).
e016604-.
ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2017-016604
Mahmood, Abda;
Roberts, Ian;
Shakur, Haleema;
(2017)
A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS]).
Trials, 18 (1).
330-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-017-2073-6
Roberts, Ian;
Edwards, Phil;
Prieto, David;
Joshi, Miland;
Mahmood, Abda;
Ker, Katharine;
Shakur, Haleema;
(2017)
Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms.
Trials, 18 (1).
48-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-016-1750-1
Roberts, Ian;
Shakur, Haleema;
(2017)
Tranexamic acid for post-partum haemorrhage in the WOMAN trial - Authors' reply.
Lancet, 390 (10102).
1584-.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(17)31942-6
Full text not available from this repository.
2016
LSHTM;
(2016)
Haleem Shakur: The WOMAN Trial.
[Podcast]
http://soundcloud.com/lshtm/haleem-shakur-the-woma...
![[img]](/style/images/fileicons/audio.png)
![[img]](/3174347/2/cover.jpg)
Dallaku, Kastriot;
Shakur, Haleema;
Edwards, Phil;
Beaumont, Danielle;
Roberts, Ian;
Huque, Sumaya;
Delius, Maria;
Mansmann, Ulrich;
(2016)
Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation.
Wellcome open research, 1.
30-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.10105.2
Dallaku, Kastriot;
Shakur, Haleema;
Roberts, Ian;
Edwards, Phil;
Beaumont, Danielle;
Delius, Maria;
Siegmund, Braun;
Gliozheni, Orion;
Tasha, Ilir;
Cenameri, Saimir;
+1 more...
Mansmann, Ulrich;
(2016)
Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study.
Scientific reports, 1.
29-.
ISSN 2045-2322
DOI: https://doi.org/10.12688/wellcomeopenres.9964.1
Ker, K;
Shakur, H;
Roberts, I;
(2016)
Does tranexamic acid prevent postpartum haemorrhage? A systematic review of randomised controlled trials.
BJOG, 123 (11).
pp. 1745-52.
ISSN 1470-0328
DOI: https://doi.org/10.1111/1471-0528.14267
![[img]](/2821097/2/Figure%201%20Effect%20of%20TXA%20on%20PPH.jpg)
Mahmood, Abda;
Roberts, Ian;
Shakur, Haleema;
Harris, Tim;
Belli, Antonio;
(2016)
Does tranexamic acid improve outcomes in traumatic brain injury?
BMJ (Clinical research ed), 354.
i4814-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.i4814
Full text not available from this repository.
Shakur, Haleema;
Fawole, Bukola;
Kuti, Modupe;
Olayemi, Oladapo;
Bello, Adenike;
Ogunbode, Olayinka;
Kotila, Taiwo;
Aimakhu, Chris O;
Huque, Sumaya;
Gregg, Meghann;
+1 more...
Roberts, Ian;
(2016)
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial.
Wellcome open research, 1.
31-.
ISSN 2398-502X
DOI: https://doi.org/10.12688/wellcomeopenres.10383.1
Shakur, Haleema;
Roberts, Ian;
Edwards, Philip;
Elbourne, Diana;
Alfirevic, Zarko;
Ronsmans, Carine;
(2016)
The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial.
Trials, 17 (1).
249-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/s13063-016-1332-2
2015
Bryceland, Catriona;
Ellis, Sophie;
Beaumont, Danielle;
Shakur, Haleema;
Coats, Timothy J;
(2015)
Good clinical practice in trauma care research: considerations for inter-hospital patient transfers.
International emergency nursing, 23 (1).
pp. 42-44.
ISSN 1755-599X
DOI: https://doi.org/10.1016/j.ienj.2014.08.001
Full text not available from this repository.
Ker, K;
Tansley, G;
Beecher, D;
Perner, A;
Shakur, H;
Harris, T;
Roberts, I;
(2015)
Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease.
The Cochrane database of systematic reviews, 2.
CD011386.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD011386.pub2
Ker, Katharine;
Roberts, Ian;
Shakur, Haleema;
Coats, Tim J;
(2015)
Antifibrinolytic drugs for acute traumatic injury.
The Cochrane database of systematic reviews, 2015 (5).
CD004896-.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD004896.pub4
Ker, Katharine;
Tansley, Gavin;
Beecher, Deirdre;
Perner, Anders;
Shakur, Haleema;
Harris, Tim;
Roberts, Ian;
(2015)
Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease.
The Cochrane database of systematic reviews, 2015 (2).
CD011386-.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD011386.pub2
Stanworth, SJ;
Manno, D;
Shakur, H;
Coats, T;
Edwards, P;
Gilmore, I;
Jairath, V;
Veitch, A;
Roberts, I;
(2015)
Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding.
Transfusion medicine (Oxford, England), 25 (3).
pp. 198-200.
ISSN 0958-7578
DOI: https://doi.org/10.1111/tme.12215
Full text not available from this repository.
2014
LSHTM;
(2014)
Living Library special - Saving the lives of trauma victims and using Big Data.
[Podcast]
http://soundcloud.com/lshtm/living-library-special...
![[img]](/style/images/fileicons/other.png)
![[img]](/2138986/2/cover.jpg)
Davies, Hugh;
Shakur, Haleema;
Padkin, Andrew;
Roberts, Ian;
Slowther, Anne-Marie;
Perkins, Gavin D;
(2014)
Guide to the design and review of emergency research when it is proposed that consent and consultation be waived.
Emergency medicine journal, 31 (10).
pp. 794-795.
ISSN 1472-0205
DOI: https://doi.org/10.1136/emermed-2014-203675
Full text not available from this repository.
Jairath, V;
Shakur, H;
Edwards, P;
Ker, K;
Manno, D;
Gilmore, I;
Veitch, A;
Stanworth, S;
Coats, T;
Roberts, I;
(2014)
PTU-185 Update On The Halt-it Trial Progress: Tranexamic Acid For The Treatment Of Gastrointestinal Haemorrhage – An International, Randomised, Double Blind Placebo Controlled Trial.
Gut, 63 (Suppl ).
A120.1-A120.
ISSN 0017-5749
DOI: https://doi.org/10.1136/gutjnl-2014-307263.259
Full text not available from this repository.
Mousa, Hatem A;
Blum, Jennifer;
Abou El Senoun, Ghada;
Shakur, Haleema;
Alfirevic, Zarko;
(2014)
Treatment for primary postpartum haemorrhage.
The Cochrane database of systematic reviews, 2014 (2).
CD003249-.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD003249.pub3
Roberts, Ian;
Coats, Timothy;
Edwards, Phil;
Gilmore, Ian;
Jairath, Vipul;
Ker, Katharine;
Manno, Daniela;
Shakur, Haleema;
Stanworth, Simon;
Veitch, Andrew;
(2014)
HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial.
Trials, 15 (1).
450-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-15-450
2013
Alvarado, José Caballero;
Dewan, Yashbir;
Elsayed, Hesham Fathy;
Gogichaishvili, Tamar;
Gupta, Sanjay;
Hunt, BJ;
Iribhogbe, Pius;
Izurieta, Mario;
Khamis, Hussein;
Komolafe, Edward O;
+10 more...
Mantilla, Jorge H Mejía;
Miranda, Jaime;
Uribe, Carlos H Morales;
Olaomi, Oluwole;
Olldashi, Fatos;
Perel, Pablo;
Ramana, PV;
Ravi, RR;
Roberts, Ian;
Shakur, Haleema;
(2013)
Tranexamic acid in trauma: we need stronger global health policy.
BMJ (Clinical research ed), 347 (jul23 ).
f4593-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.f4593
Full text not available from this repository.
Edwards, Phil;
Shakur, Haleema;
Barnetson, Lin;
Prieto, David;
Evans, Stephen;
Roberts, Ian;
(2013)
Central and statistical data monitoring in the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial.
Clinical trials (London, England), 11 (3).
pp. 336-343.
ISSN 1740-7745
DOI: https://doi.org/10.1177/1740774513514145
Full text not available from this repository.
Roberts, I;
Shakur, H;
Coats, T;
Hunt, B;
Balogun, E;
Barnetson, L;
Cook, L;
Kawahara, T;
Perel, P;
Prieto-Merino, D;
+3 more...
Ramos, M;
Cairns, J;
Guerriero, C;
(2013)
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Health technology assessment (Winchester, England), 17 (10).
pp. 1-79.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta17100
Roberts, I;
Shakur, H;
Coats, T;
Hunt, B;
Balogun, E;
Barnetson, L;
Cook, L;
Kawahara, T;
Perel, P;
Prieto-Merino, D;
+3 more...
Ramos, M;
Cairns, J;
Guerriero, C;
(2013)
The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients.
Health technology assessment (Winchester, England), 17 (10).
pp. 1-79.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta17240
Shakur, Haleema;
Roberts, Ian;
Piot, Peter;
Horton, Richard;
Krug, Etienne;
Mersch, Jeannot;
(2013)
A promise to save 100,000 trauma patients.
Lancet, 380 (9859).
pp. 2062-2063.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(12)62037-6
Full text not available from this repository.
2012
Alvarado, JC;
Dewan, Y;
Elsayed, HF;
Gogichaishvili, T;
Gupta, S;
Hunt, BJ;
Iribhogbe, P;
Izurieta, M;
Khamis, H;
Komolafe, EO;
+10 more...
Mejía Mantilla, JH;
Miranda, J;
Morales Uribe, CH;
Olaomi, O;
Olldashi, F;
Perel, P;
Ramana, PV;
Ravi, RR;
Roberts, IR;
Shakur, H;
(2012)
Tranexamic acid in trauma: we need stronger global health policy.
BMJ, 347 (4593).
ISSN 0959-535X
DOI: https://doi.org/10.1136/bmj.f4593
Dewan, Yashbir;
Komolafe, Edward O;
Mejía-Mantilla, Jorge H;
Perel, Pablo;
Roberts, Ian;
Shakur, Haleema;
CRASH-3 Collaborators;
(2012)
CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial.
TRIALS, 13 (1).
87-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-13-87
Ker, Katharine;
Edwards, Phil;
Perel, Pablo;
Shakur, Haleema;
Roberts, Ian;
(2012)
Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.
BMJ (Clinical research ed), 344 (may17 ).
e3054-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.e3054
Ker, Katharine;
Kiriya, Junko;
Perel, Pablo;
Edwards, Phil;
Shakur, Haleema;
Roberts, Ian;
(2012)
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial.
BMC emergency medicine, 12 (1).
3-.
ISSN 1471-227X
DOI: https://doi.org/10.1186/1471-227X-12-3
Perel, P;
Al-Shahi Salman, R;
Kawahara, T;
Morris, Z;
Prieto-Merino, D;
Roberts, I;
Sandercock, P;
Shakur, H;
Wardlaw, J;
(2012)
CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial.
Health technology assessment (Winchester, England), 16 (13).
iii-54.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta16130
Perel, Pablo;
Prieto-Merino, David;
Shakur, Haleema;
Clayton, Tim;
Lecky, Fiona;
Bouamra, Omar;
Russell, Rob;
Faulkner, Mark;
Steyerberg, Ewout W;
Roberts, Ian;
(2012)
Predicting early death in patients with traumatic bleeding: development and validation of prognostic model.
BMJ (Clinical research ed), 345 (aug15 ).
e5166-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.e5166
Perel, Pablo;
Salman, RAS;
Kawahara, T;
Morris, Z;
Prieto-merino, David;
Roberts, Ian;
Sandercock, P;
Shakur-still, Haleema;
Wardlaw, J;
(2012)
CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury - a nested, randomised, placebo-controlled trial.
Health technology assessment (Winchester, England), 16 (13).
1-+.
ISSN 1366-5278
DOI: https://doi.org/10.3310/hta16130
Roberts, Ian;
Perel, Pablo;
Prieto-Merino, David;
Shakur, Haleema;
Coats, Tim;
Hunt, Beverley J;
Lecky, Fiona;
Brohi, Karim;
Willett, Keith;
CRASH-2 Collaborators;
(2012)
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial.
BMJ (Clinical research ed), 345 (sep11 ).
e5839-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.e5839
Roberts, Ian;
Shakur, Haleema;
Ker, Katharine;
Coats, Tim;
CRASH-2 Trial collaborators;
(2012)
Antifibrinolytic drugs for acute traumatic injury.
The Cochrane database of systematic reviews, 129 (1).
CD004896-.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD004896.pub3
Turner, Elizabeth L;
Perel, Pablo;
Clayton, Tim;
Edwards, Phil;
Hernández, Adrian V;
Roberts, Ian;
Shakur, Haleema;
Steyerberg, Ewout W;
CRASH trial collaborators;
(2012)
Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury.
Journal of clinical epidemiology, 65 (5).
pp. 474-481.
ISSN 0895-4356
DOI: https://doi.org/10.1016/j.jclinepi.2011.08.012
Full text not available from this repository.
van Leeuwen, Nikki;
Lingsma, Hester F;
Perel, Pablo;
Lecky, Fiona;
Roozenbeek, Bob;
Lu, Juan;
Shakur, Haleema;
Weir, James;
Steyerberg, Ewout W;
Maas, Andrew IR;
+3 more...
International Mission on Prognosis and Clinical Trial Design in ;
Corticosteroid Randomization After Significant Head Injury Trial;
Trauma Audit and Research Network;
(2012)
Prognostic value of major extracranial injury in traumatic brain injury: an individual patient data meta-analysis in 39,274 patients.
Neurosurgery, 70 (4).
pp. 811-818.
ISSN 0148-396X
DOI: https://doi.org/10.1227/NEU.0b013e318235d640
Full text not available from this repository.
2011
Andrews, Peter JD;
Sinclair, Helen Louise;
Battison, Claire G;
Polderman, Kees H;
Citerio, Giuseppe;
Mascia, Luciana;
Harris, Bridget A;
Murray, Gordon D;
Stocchetti, Nino;
Menon, David K;
+3 more...
Shakur, Haleema;
De Backer, Daniel;
Eurotherm3235Trial collaborators;
(2011)
European society of intensive care medicine study of therapeutic hypothermia (32-35 °C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial).
Trials, 12 (1).
8-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-12-8
CRASH-2 collaborators;
Roberts, Ian;
Shakur, Haleema;
Afolabi, Adefemi;
Brohi, Karim;
Coats, Tim;
Dewan, Yashbir;
Gando, Satoshi;
Guyatt, Gordon;
Hunt, BJ;
+4 more...
Morales, Carlos;
Perel, Pablo;
Prieto-Merino, David;
Woolley, Tom;
(2011)
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
Lancet, 377 (9771).
1096-1101.e2.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(11)60278-X
Guerriero, Carla;
Cairns, John;
Perel, Pablo;
Shakur, Haleema;
Roberts, Ian;
CRASH 2 trial collaborators;
(2011)
Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial.
PloS one, 6 (5).
e18987-.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0018987
McDonald, Alison M;
Treweek, Shaun;
Shakur, Haleema;
Free, Caroline;
Knight, Rosemary;
Speed, Chris;
Campbell, Marion K;
(2011)
Using a business model approach and marketing techniques for recruitment to clinical trials.
Trials, 12 (1).
74-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-12-74
Ngo, Thoai D;
Park, Min Hae;
Shakur, Haleema;
Free, Caroline;
(2011)
Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review.
Bulletin of the World Health Organization, 89 (5).
pp. 360-370.
ISSN 0042-9686
DOI: https://doi.org/10.2471/BLT.10.084046
Roberts, I;
Shakur, H;
Ker, K;
Coats, T;
CRASH-2 Trial collaborators;
(2011)
Antifibrinolytic drugs for acute traumatic injury.
The Cochrane database of systematic reviews, 1 (1).
CD004896.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD004896.pub3
Roberts, Ian;
Chalmers, Iain;
Shakur, Haleema;
Prieto-Merino, David;
Nicholl, Jon;
(2011)
Consent in emergency care research – Authors' reply.
Lancet, 378 (9785).
p. 27.
ISSN 0140-6736
DOI: https://doi.org/10.1016/s0140-6736(11)61014-3
Full text not available from this repository.
Roberts, Ian;
Prieto-Merino, David;
Perel, Pablo;
Shakur, Haleema;
(2011)
Early administration of tranexamic acid in trauma patients – Authors' reply.
Lancet, 378 (9785).
p. 28.
ISSN 0140-6736
DOI: https://doi.org/10.1016/s0140-6736(11)61016-7
Full text not available from this repository.
Roberts, Ian;
Prieto-Merino, David;
Shakur, Haleema;
Chalmers, Iain;
Nicholl, Jon;
(2011)
Effect of consent rituals on mortality in emergency care research.
Lancet, 377 (9771).
pp. 1071-1072.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(11)60317-6
Full text not available from this repository.
2010
Farrell, Barbara;
Kenyon, Sara;
Shakur, Haleema;
(2010)
Managing clinical trials.
Trials, 11 (1).
78-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-11-78
Guerriero, Carla;
Cairns, John;
Jayaraman, Sudha;
Roberts, Ian;
Perel, Pablo;
Shakur, Haleema;
(2010)
Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation.
Cost effectiveness and resource allocation, 8 (1).
1-.
ISSN 1478-7547
DOI: https://doi.org/10.1186/1478-7547-8-1
Perel, Pablo;
Roberts, Ian;
Shakur, Haleema;
Thinkhamrop, Bandit;
Phuenpathom, Nakornchai;
Yutthakasemsunt, Surakrant;
(2010)
Haemostatic drugs for traumatic brain injury.
The Cochrane database of systematic reviews, 1 (1).
CD007877-.
ISSN 1469-493X
DOI: https://doi.org/10.1002/14651858.CD007877.pub2
Shakur, H;
Roberts, I;
Perel, P;
(2010)
Tranexamic acid for trauma Reply.
Lancet, 376 (9746).
pp. 1050-1051.
ISSN 0140-6736
https://researchonline.lshtm.ac.uk/id/eprint/2479
Full text not available from this repository.
Shakur, Haleema;
Elbourne, Diana;
Gülmezoglu, Metin;
Alfirevic, Zarko;
Ronsmans, Carine;
Allen, Elizabeth;
Roberts, Ian;
(2010)
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial.
Trials, 11 (1).
40-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-11-40
2009
Ferrer, Pili;
Roberts, Ian;
Sydenham, Emma;
Blackhall, Karen;
Shakur, Haleema;
(2009)
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review.
BMC pregnancy and childbirth, 9 (1).
29-.
ISSN 1471-2393
DOI: https://doi.org/10.1186/1471-2393-9-29
Shakur, Haleema;
Andrews, Peter;
Asser, Toomas;
Balica, Laura;
Boeriu, Cristian;
Quintero, Juan Diego Ciro;
Dewan, Yashbir;
Druwé, Patrick;
Fletcher, Olivia;
Frost, Chris;
+10 more...
Hartzenberg, Bennie;
Mantilla, Jorge Mejia;
Murillo-Cabezas, Francisco;
Pachl, Jan;
Ravi, Ramalingam R;
Rätsep, Indrek;
Sampaio, Cristina;
Singh, Manmohan;
Svoboda, Petr;
Roberts, Ian;
(2009)
The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury.
Trials, 10 (1).
109-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-10-109
2008
De Silva, Mary J;
Roberts, Ian;
Perel, Pablo;
Edwards, Phil;
Kenward, Michael G;
Fernandes, Janice;
Shakur, Haleema;
Patel, Vikram;
CRASH Trial Collaborators;
(2008)
Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countries.
International journal of epidemiology, 38 (2).
pp. 452-458.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyn189
Full text not available from this repository.
MRC CRASH Trial Collaborators;
Perel, Pablo;
Arango, Miguel;
Clayton, Tim;
Edwards, Phil;
Komolafe, Edward;
Poccock, Stuart;
Roberts, Ian;
Shakur, Haleema;
Steyerberg, Ewout;
+1 more...
Yutthakasemsunt, Surakrant;
(2008)
Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients.
BMJ, 336 (7641).
pp. 425-429.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.39461.643438.25
Perel, Pablo;
Edwards, Phil;
Shakur, Haleema;
Roberts, Ian;
(2008)
Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury.
BMC medical research methodology, 8 (1).
72-.
ISSN 1471-2288
DOI: https://doi.org/10.1186/1471-2288-8-72
2007
Francis, David;
Roberts, Ian;
Elbourne, Diana R;
Shakur, Haleema;
Knight, Rosemary C;
Garcia, Jo;
Snowdon, Claire;
Entwistle, Vikki A;
McDonald, Alison M;
Grant, Adrian M;
+1 more...
Campbell, Marion K;
(2007)
Marketing and clinical trials: a case study.
Trials, 8 (1).
37-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-8-37
Perel, Pablo;
Wasserberg, Jonathan;
Ravi, Ramalingam R;
Shakur, Haleema;
Edwards, Phil;
Roberts, Ian;
(2007)
Prognosis following head injury: a survey of doctors from developing and developed countries.
Journal of evaluation in clinical practice, 13 (3).
pp. 464-465.
ISSN 1356-1294
DOI: https://doi.org/10.1111/j.1365-2753.2006.00713.x
Full text not available from this repository.
Shakur, Haleema;
Roberts, Ian;
Barnetson, Lin;
Coats, Tim;
(2007)
Clinical trials in emergency situations.
BMJ (Clinical research ed), 334 (7586).
pp. 165-166.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.39097.582130.80
2006
Chung, CH;
Freiberger, A;
Kalkum, M;
Luntz, SP;
Shakur, H;
Seiler, CM;
(2006)
CRASH2 in Germany [ISRCTN86750102].
Trials, 7 (1).
22-.
ISSN 1745-6215
DOI: https://doi.org/10.1186/1745-6215-7-22
Coats, TJ;
Ng, G;
Shakur, H;
(2006)
Consent in emergency research.
Emergency medicine journal, 23 (6).
pp. 489-490.
ISSN 1472-0205
DOI: https://doi.org/10.1136/emj.2005.031005
Full text not available from this repository.
2005
Coats, TJ;
Shakur, H;
(2005)
Consent in emergency research: new regulations.
Emergency medicine journal, 22 (10).
pp. 683-685.
ISSN 1472-0205
DOI: https://doi.org/10.1136/emj.2005.024588
Full text not available from this repository.
Coats, Tim;
Hunt, Beverley;
Roberts, Ian;
Shakur, Haleema;
(2005)
Antifibrinolytic agents in traumatic hemorrhage.
MedGenMed, 7 (1).
9-.
ISSN 1531-0132
https://researchonline.lshtm.ac.uk/id/eprint/10696
Full text not available from this repository.
Coats, Tim;
Hunt, Beverley;
Roberts, Ian;
Shakur, Haleema;
(2005)
Antifibrinolytic agents in traumatic hemorrhage: a large scale randomized controlled trial is needed.
Croatian medical journal, 46 (1).
pp. 146-147.
ISSN 0353-9504
https://researchonline.lshtm.ac.uk/id/eprint/6403
Coats, Tim;
Hunt, Beverly;
Roberts, Ian;
Shakur, Haleema;
(2005)
Antifibrinolytic agents in traumatic haemorrhage.
PLoS medicine, 2 (3).
e64-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.0020064
Edwards, Phil;
Arango, Miguel;
Balica, Laura;
Cottingham, Rowland;
El-Sayed, Hesham;
Farrell, Barbara;
Fernandes, Janice;
Gogichaisvili, Tamar;
Golden, Nyoman;
Hartzenberg, Bennie;
+25 more...
Husain, Mazhar;
Ulloa, Mario Izurieta;
Jerbi, Zouheir;
Khamis, Hussein;
Komolafe, Edward;
Laloë, Véronique;
Lomas, Gabrielle;
Ludwig, Silke;
Mazairac, Guy;
Muñoz Sanchéz, Maria de los Angeles;
Nasi, Luis;
Olldashi, Fatos;
Plunkett, Patrick;
Roberts, Ian;
Sandercock, Peter;
Shakur, Haleema;
Soler, Caridad;
Stocker, Reto;
Svoboda, Petr;
Trenkler, Stefan;
Venkataramana, NK;
Wasserberg, Jonathan;
Yates, David;
Yutthakasemsunt, Surakrant;
CRASH trial collaborators;
(2005)
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months.
Lancet, 365 (9475).
pp. 1957-1959.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(05)66552-X
Full text not available from this repository.
Roberts, I;
Edwards, P;
Shakur, H;
(2005)
Possible explanations for the results of CRASH.
Lancet, 365 (9455).
pp. 213-214.
ISSN 0140-6736
DOI: https://doi.org/10.1016/s0140-6736(05)17735-6
Full text not available from this repository.
Roberts, Ian;
Shakur, Haleema;
Edwards, Phil;
Yates, David;
Sandercock, Peter;
(2005)
Trauma care research and the war on uncertainty.
BMJ, 331 (7525).
pp. 1094-1096.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.331.7525.1094
2004
Roberts, Ian;
Yates, David;
Sandercock, Peter;
Farrell, Barbara;
Wasserberg, Jonathan;
Lomas, Gabrielle;
Cottingham, Rowland;
Svoboda, Petr;
Brayley, Nigel;
Mazairac, Guy;
+13 more...
Laloë, Véronique;
Muñoz-Sánchez, Angeles;
Arango, Miguel;
Hartzenberg, Bennie;
Khamis, Hussein;
Yutthakasemsunt, Surakrant;
Komolafe, Edward;
Olldashi, Fatos;
Yadav, Yadram;
Murillo-Cabezas, Francisco;
Shakur, Haleema;
Edwards, Phil;
CRASH trial collaborators;
(2004)
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial.
Lancet, 364 (9442).
pp. 1321-1328.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(04)17188-2
Full text not available from this repository.
2003
Shakur, Haleema;
(2003)
A COPD self management programme reduced hospital use and improved health status.
Evidence-based nursing, 6 (4).
111-.
ISSN 1367-6539
DOI: https://doi.org/10.1136/ebn.6.4.111
Full text not available from this repository.