The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.

CRASH-2 collaborators; Roberts, I; Shakur, H; Afolabi, A; Brohi, K; Coats, T; Dewan, Y; Gando, S; Guyatt, G; Hunt, BJ; +563 more... Morales, C; Perel, P; Prieto-Merino, D; Woolley, T; , COLLABORATORS; Dakubo, J; Gogichaishvili, T; Golden, N; Izurieta, M; Khamis, H; Komolafe, E; Loría-Castellanos, J; Mejía-Mantilla, J; Miranda, J; Muñoz, Á; Mutiso, V; Okwen, P; Ortiz, Z; Pascual, M; Ravi, R; Roslani, A; Trenkler, S; Volpi, A; Yutthakasemsunt, S; Roberts, I; Shakur, H; Perel, P; Barnetson, L; Ramos, M; Cook, L; Kawahara, T; Balogun, E; Berle, M; Barrow, C; Brady, T; Rubery, C; Wayte, J; To, C; Franklin, I; Chaudhry, B; Coats, T; Deakin, C; Goodacre, S; Hunt, B; Meddings, D; Peto, R; Roberts, I; Sandercock, P; Roberts, I; Shakur, H; Coats, T; Edwards, P; Hunt, B; Ramos, M; Collins, R; Grant, A; Myburgh, J; Baxter, A; Olldashi, F; Kerçi, M; Zhurda, T; Ruçi, K; Banushi, A; Traverso, MS; Jiménez, J; Balbi, J; Dellera, C; Svampa, S; Quintana, G; Piñero, G; Teves, J; Seppelt, I; Mountain, D; Balogh, Z; Zaman, M; Druwé, P; Rutsaert, R; Mazairac, G; Pascal, F; Yvette, Z; Chancellin, D; Okwen, P; Djokam-Liapoe, J; Jangwa, E; Mbuagbaw, L; Fointama, N; Pascal, F; Baillie, F; Jiang, JY; Gao, GY; Bao, YH; Morales, C; Sierra, J; Naranjo, S; Correa, C; Gómez, C; Herrera, J; Caicedo, L; Rojas, A; Pastas, H; Miranda, H; Constaín, A; Perdomo, M; Muñoz, D; Duarte, Á; Vásquez, E; Ortiz, C; Ayala, B; Delgado, H; Benavides, G; Rosero, L; Mejía-Mantilla, J; Varela, A; Calle, M; Castillo, J; García, A; Ciro, J; Villa, C; Panesso, R; Flórez, L; Gallego, A; Puentes-Manosalva, F; Medina, L; Márquez, K; Romero, AR; Hernández, R; Martínez, J; Gualteros, W; Urbina, Z; Velandia, J; Benítez, F; Trochez, A; Villarreal, A; Pabón, P; Delgado, H; López, H; Quintero, L; Rubiano, A; Tamayo, J; Piñera, M; Martínez, D; Martínez, H; Casola, E; Domínguez, M; Herrera, C; Iraola, M; Rojas, O; Pastrana, I; Rodríguez, D; de la Campa, S.Á; Fortún, T; Larrea, M; Aragón, L; Madrazo, A; Svoboda, P; Izurieta, M; Daccach, A; Altamirano, M; Ortega, A; Cárdenas, B; González, L; Ochoa, M; Ortega, F; Quichimbo, F; Guiñanzaca, J; Zavala, I; Segura, S; Jerez, J; Acosta, D; Yánez, F; Camacho, R; Khamis, H; Shafei, H; Kheidr, A; Nasr, H; Mosaad, M; Rizk, S; El Sayed, H; Moati, T; Hokkam, E; Amin, M; Lowis, H; Fawzy, M; Bedir, N; Aldars, M; Rodríguez, V; Tobar, J; Alvarenga, J; Shalamberidze, B; Demuria, E; Rtveliashvili, N; Chutkerashvili, G; Dotiashvili, D; Gogichaishvili, T; Ingorokva, G; Kazaishvili, D; Melikidze, B; Iashvili, N; Tomadze, G; Chkhikvadze, M; Khurtsidze, L; Lomidze, Z; Dzagania, D; Kvachadze, N; Gotsadze, G; Kaloiani, V; Kajaia, N; Dakubo, J; Naaeder, S; Sowah, P; Yusuf, A; Ishak, A; Selasi-Sefenu, P; Sibiri, B; Sarpong-Peprah, S; Boro, T; Bopaiah, K; Shetty, K; Subbiah, R; Mulla, L; Doshi, A; Dewan, Y; Grewal, S; Tripathy, P; Mathew, J; Gupta, B; Lal, A; Choudhury, M; Gupta, S; Gupta, S; Chug, A; Pamidimukkala, V; Jagannath, P; Maharaj, M; Vommi, R; Gudipati, N; Chhang, WH; Patel, P; Suthar, N; Banker, D; Patel, J; Dharap, S; Kamble, R; Patkar, S; Lohiya, S; Saraf, R; Kumar, D; Parihar, S; Gupta, R; Mangual, R; Alagumuthu; Kooper, D; Mohapatra, C; David, S; Rajaleelan, W; Appas; Pangi, A; Saraf, V; Chikareddy, S; Mankar, S; Golhar, A; Sakhare, R; Wagh, N; Lal, A; Hazarika, D; Chaudhuri, P; Ketan, P; Purohit, G; Purohit, Y; Pandya, M; Gupta, R; Kiran, S; Walia, S; Goyal, S; Goyal, S; Goyal, S; Gupta, S; Attri, A; Sharma, R; Oberai, A; Oberai, M; Oberoi, S; Tripathi, GK; Peettakkandy, V; Karuthillath, P; Vadakammuriyil, P; Pol, J; Pol, S; Saste, M; Raul, S; Tiwari, S; Nelly, N; Chidambaram, M; Kollengode, V; Thampan, S; Rajan, S; Rajan, S; Raju, S; Sharma, R; Babu, SV; Sumathi, C; Chatterjee, P; Agarwal, A; Magar, H; Magar, M; Singh, M; Gupta, D; Lal, A; Haloi, K; Sagdeo, V; Giri, P; Verma, N; Jariwala, R; Goti, A; Prabhu-Gaonkar, A; Utagi, S; Joshi, M; Agrawal, R; Sharma, G; Saini, G; Tewari, V; Yadav, Y; Parihar, V; Venkataramana, N; Rao, S; Reddy, N; Hathila, V; Das, V; Agaja, K; Purohit, A; Lahari, A; Bhagchandani, R; Vidyasagar, B; Sachan, PK; Das, T; Vyas, S; Bhattacharjee, S; Sancheti, P; Manoj, T; Moideen, M; Pansey, K; Chandrasekaran, VP; Saikia, K; Tata, H; Vhora, S; Shah, A; Rangad, G; Rajasekaran, S; Shankarlal, ST; Devadoss, S; Saleem, M; Pillay, H; Hazarika, Zq; Deshmukh, P; Murugappan, SP; Jaiswal, A; Vangani, D; Modha, P; Chonzik, C; Praveen, M; Sethurayar, V; Ipe, S; Shetty, N; Shah, A; Gupta, RP; Jain, V; Shah, K; Dwikoryanto, M; Golden, N; Atmadjaya, K; Wiargitha, K; Sudiasa, K; Suwedagatha, G; Bal'afif, F; Budipramana, V; Tabrani; Lemuel, A; Chandra, S; Ama, F; Sherafatkazemzadeh, E; Moradi, E; Sheikhi, A; Ziaee, A; Fanaei, A; Hajinasrollah, E; Heidari, K; Mohammad, B; Hadi, N; Perone, G; de Peri, E; Volpi, A; Johnson, J; Abe, M; Mutiso, V; Okanga, B; Ojuka, D; Abdullah, B; Rahman, H; Noh, Y; Jamaluddin, S; Dawal, H; Roslani, A; Law, CW; Devashanti, P; Wahab, Y; Velaiutham, S; Dato, R; Loría, J; Montes, E; Gómez, E; Cazales, V; Bautista, P; Bautista, R; Ahumada, D; Hernández, E; Velásquez, G; Ortega, P; Lira, G; Estrada, F; Martínez, J; Martínez, J; Casasola, J; Olaomi, O; Abubakar, Y; Apollo, K; Badejo, O; Ihekire, O; Iribhogbe, P; Oludiran, O; Obeta, E; Okojie, C; Udefiagbon, E; Komolafe, E; Olaleye, P; Uzochukwu, T; Onakpoya, U; Dongo, A; Thanni, L; Afolabi, A; Akinola, T; Ademola, A; Akute, O; Khalid, L; Abubakar, L; Aminu, M; Ogirima, M; Attansey, A; Michael, D; Aremu, O; Olugbenga, O; Ukpong, U; Salman, Y; Obianyo, N; Ani, C; Ezeadawi, R; Kehinde, O; Olaide, A; Jogo, A; Bitto, T; Anyanwu, S; Mbonu, O; Oludara, M; Somoye, M; Shehu, B; Ismail, N; Katchy, A; Ndoma-Egba, R; Grace-Inah, N; Songden, Z; Abdulraheem, A; Otu, A; Nottidge, T; Inyang, D; Idiapho, D; Giebel, H; Hassan, R; Adisa, A; Akinkuolie, A; Okam, K; Musa, A; Falope, I; Eze, J; Caballero, J; Azabache, W; Salirrosas, O; Soto, A; Torres, E; Ramírez, G; Pérez, M; Malca, C; Velez, J; Yepez, R; Yupanqui, H; Lagos, P; Rodriguez, D; Flores, J; Moya, A; Barrionuevo, A; Gonzales-Portillo, M; Núñez, E; Eldawlatly, A; Naami, MA; Delvi, B; Alyafi, W; Djurovic, B; Ng, I; Yaghi, A; Laincz, A; Trenkler, S; Valky, J; Modiba, M; Legodi, P; Rangaka, T; Wallis, L; Muñoz, Á; Serrano, A; Marcos, P; Rubi, M; de la Torre, V; Ellawala, R; Wijeratna, S; Gunaratna, L; Wijayanayaka, C; Nungu, K; Haonga, B; Mtapa, G; Yutthakasemsunt, S; Kittiwattanagul, W; Piyavechvirat, P; Impool, T; Thummaraj, S; Salaeh, R; Tangchitvittaya, S; Wattanakrai, K; Jiravongbunrod, T; Soonthornthum, C; Meephant, S; Subsompon, P; Pensuwan, P; Chamnongwit, W; Jerbi, Z; Cherif, A; Nash, M; Harris, T; Banerjee, J; Freij, R; Kendall, J; Moore, S; Townend, W; Cottingham, R; Becker, D; Lloyd, S; Burdett-Smith, P; Mirza, K; Webster, A; Brady, S; Grocutt, A; Thurston, J; Lecky, F; Goodacre, S; Mulla, Y; Sakala, D; Chengo, C; (2011) The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet, 377 (9771). 1096-101, 1101.e1-2. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(11)60278-X

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