Alvarado, José Caballero; Dewan, Yashbir; Elsayed, Hesham Fathy; Gogichaishvili, Tamar; Gupta, Sanjay; Hunt, BJ; Iribhogbe, Pius; Izurieta, Mario; Khamis, Hussein; Komolafe, Edward O; +10 more... Mantilla, Jorge H Mejía; Miranda, Jaime; Uribe, Carlos H Morales; Olaomi, Oluwole; Olldashi, Fatos; Perel, Pablo; Ramana, PV; Ravi, RR; Roberts, Ian; Shakur, Haleema; (2013) Tranexamic acid in trauma: we need stronger global health policy. BMJ (Clinical research ed), 347 (jul23 ). f4593-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.f4593 Full text not available from this repository.

Bryceland, Catriona; Ellis, Sophie; Beaumont, Danielle; Shakur, Haleema; Coats, Timothy J; (2015) Good clinical practice in trauma care research: considerations for inter-hospital patient transfers. International emergency nursing, 23 (1). pp. 42-44. ISSN 1755-599X DOI: https://doi.org/10.1016/j.ienj.2014.08.001 Full text not available from this repository.

Coats, TJ; Ng, G; Shakur, H; (2006) Consent in emergency research. Emergency medicine journal, 23 (6). pp. 489-490. ISSN 1472-0205 DOI: https://doi.org/10.1136/emj.2005.031005 Full text not available from this repository.

Coats, TJ; Shakur, H; (2005) Consent in emergency research: new regulations. Emergency medicine journal, 22 (10). pp. 683-685. ISSN 1472-0205 DOI: https://doi.org/10.1136/emj.2005.024588 Full text not available from this repository.

Coats, Tim; Hunt, Beverley; Roberts, Ian; Shakur, Haleema; (2005) Antifibrinolytic agents in traumatic hemorrhage. MedGenMed, 7 (1). 9-. ISSN 1531-0132 https://researchonline.lshtm.ac.uk/id/eprint/10696 Full text not available from this repository.

Davies, Hugh; Shakur, Haleema; Padkin, Andrew; Roberts, Ian; Slowther, Anne-Marie; Perkins, Gavin D; (2014) Guide to the design and review of emergency research when it is proposed that consent and consultation be waived. Emergency medicine journal, 31 (10). pp. 794-795. ISSN 1472-0205 DOI: https://doi.org/10.1136/emermed-2014-203675 Full text not available from this repository.

De Silva, Mary J; Roberts, Ian; Perel, Pablo; Edwards, Phil; Kenward, Michael G; Fernandes, Janice; Shakur, Haleema; Patel, Vikram; CRASH Trial Collaborators; (2008) Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countries. International journal of epidemiology, 38 (2). pp. 452-458. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyn189 Full text not available from this repository.

Edwards, Phil; Arango, Miguel; Balica, Laura; Cottingham, Rowland; El-Sayed, Hesham; Farrell, Barbara; Fernandes, Janice; Gogichaisvili, Tamar; Golden, Nyoman; Hartzenberg, Bennie; +25 more... Husain, Mazhar; Ulloa, Mario Izurieta; Jerbi, Zouheir; Khamis, Hussein; Komolafe, Edward; Laloë, Véronique; Lomas, Gabrielle; Ludwig, Silke; Mazairac, Guy; Muñoz Sanchéz, Maria de los Angeles; Nasi, Luis; Olldashi, Fatos; Plunkett, Patrick; Roberts, Ian; Sandercock, Peter; Shakur, Haleema; Soler, Caridad; Stocker, Reto; Svoboda, Petr; Trenkler, Stefan; Venkataramana, NK; Wasserberg, Jonathan; Yates, David; Yutthakasemsunt, Surakrant; CRASH trial collaborators; (2005) Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months. Lancet, 365 (9475). pp. 1957-1959. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(05)66552-X Full text not available from this repository.

Edwards, Phil; Shakur, Haleema; Barnetson, Lin; Prieto, David; Evans, Stephen; Roberts, Ian; (2013) Central and statistical data monitoring in the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial. Clinical trials (London, England), 11 (3). pp. 336-343. ISSN 1740-7745 DOI: https://doi.org/10.1177/1740774513514145 Full text not available from this repository.

Jairath, V; Shakur, H; Edwards, P; Ker, K; Manno, D; Gilmore, I; Veitch, A; Stanworth, S; Coats, T; Roberts, I; (2014) PTU-185 Update On The Halt-it Trial Progress: Tranexamic Acid For The Treatment Of Gastrointestinal Haemorrhage – An International, Randomised, Double Blind Placebo Controlled Trial. Gut, 63 (Suppl ). A120.1-A120. ISSN 0017-5749 DOI: https://doi.org/10.1136/gutjnl-2014-307263.259 Full text not available from this repository.

Mahmood, Abda; Roberts, Ian; Shakur, Haleema; Harris, Tim; Belli, Antonio; (2016) Does tranexamic acid improve outcomes in traumatic brain injury? BMJ (Clinical research ed), 354. i4814-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.i4814 Full text not available from this repository.

Perel, Pablo; Wasserberg, Jonathan; Ravi, Ramalingam R; Shakur, Haleema; Edwards, Phil; Roberts, Ian; (2007) Prognosis following head injury: a survey of doctors from developing and developed countries. Journal of evaluation in clinical practice, 13 (3). pp. 464-465. ISSN 1356-1294 DOI: https://doi.org/10.1111/j.1365-2753.2006.00713.x Full text not available from this repository.

Roberts, I; Edwards, P; Shakur, H; (2005) Possible explanations for the results of CRASH. Lancet, 365 (9455). pp. 213-214. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(05)17735-6 Full text not available from this repository.

Roberts, Ian; Chalmers, Iain; Shakur, Haleema; Prieto-Merino, David; Nicholl, Jon; (2011) Consent in emergency care research – Authors' reply. Lancet, 378 (9785). p. 27. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(11)61014-3 Full text not available from this repository.

Roberts, Ian; Prieto-Merino, David; Perel, Pablo; Shakur, Haleema; (2011) Early administration of tranexamic acid in trauma patients – Authors' reply. Lancet, 378 (9785). p. 28. ISSN 0140-6736 DOI: https://doi.org/10.1016/s0140-6736(11)61016-7 Full text not available from this repository.

Roberts, Ian; Prieto-Merino, David; Shakur, Haleema; Chalmers, Iain; Nicholl, Jon; (2011) Effect of consent rituals on mortality in emergency care research. Lancet, 377 (9771). pp. 1071-1072. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(11)60317-6 Full text not available from this repository.

Roberts, Ian; Shakur, Haleema; (2017) Tranexamic acid for post-partum haemorrhage in the WOMAN trial - Authors' reply. Lancet, 390 (10102). 1584-. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(17)31942-6 Full text not available from this repository.

Roberts, Ian; Shakur, Haleema; Bellomo, Rinaldo; Bion, Julian; Finfer, Simon; Hunt, Beverley; Myburgh, John; Perner, Anders; Reinhart, Konrad; (2018) Should hydroxyethyl starch be banned? - Authors' reply. Lancet, 392 (10142). 119-. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(18)31179-6 Full text not available from this repository.

Roberts, Ian; Shakur, Haleema; Bellomo, Rinaldo; Bion, Julian; Finfer, Simon; Hunt, Beverley; Myburgh, John; Perner, Anders; Reinhart, Konrad; (2018) Hydroxyethyl starch solutions and patient harm. Lancet, 391 (10122). 736-. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(18)30255-1 Full text not available from this repository.

Roberts, Ian; Yates, David; Sandercock, Peter; Farrell, Barbara; Wasserberg, Jonathan; Lomas, Gabrielle; Cottingham, Rowland; Svoboda, Petr; Brayley, Nigel; Mazairac, Guy; +13 more... Laloë, Véronique; Muñoz-Sánchez, Angeles; Arango, Miguel; Hartzenberg, Bennie; Khamis, Hussein; Yutthakasemsunt, Surakrant; Komolafe, Edward; Olldashi, Fatos; Yadav, Yadram; Murillo-Cabezas, Francisco; Shakur, Haleema; Edwards, Phil; CRASH trial collaborators; (2004) Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial. Lancet, 364 (9442). pp. 1321-1328. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(04)17188-2 Full text not available from this repository.

Shakur, H; Roberts, I; Perel, P; (2010) Tranexamic acid for trauma Reply. Lancet, 376 (9746). pp. 1050-1051. ISSN 0140-6736 https://researchonline.lshtm.ac.uk/id/eprint/2479 Full text not available from this repository.

Shakur, Haleema; (2003) A COPD self management programme reduced hospital use and improved health status. Evidence-based nursing, 6 (4). 111-. ISSN 1367-6539 DOI: https://doi.org/10.1136/ebn.6.4.111 Full text not available from this repository.

Shakur, Haleema; Roberts, Ian; Piot, Peter; Horton, Richard; Krug, Etienne; Mersch, Jeannot; (2013) A promise to save 100,000 trauma patients. Lancet, 380 (9859). pp. 2062-2063. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(12)62037-6 Full text not available from this repository.

Stanworth, SJ; Manno, D; Shakur, H; Coats, T; Edwards, P; Gilmore, I; Jairath, V; Veitch, A; Roberts, I; (2015) Extending evidence for the use of tranexamic acid from traumatic haemorrhage to other patients with major bleeding: do we need more than one haemorrhage protocol? The case of gastrointestinal bleeding. Transfusion medicine (Oxford, England), 25 (3). pp. 198-200. ISSN 0958-7578 DOI: https://doi.org/10.1111/tme.12215 Full text not available from this repository.

Turner, Elizabeth L; Perel, Pablo; Clayton, Tim; Edwards, Phil; Hernández, Adrian V; Roberts, Ian; Shakur, Haleema; Steyerberg, Ewout W; CRASH trial collaborators; (2012) Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury. Journal of clinical epidemiology, 65 (5). pp. 474-481. ISSN 0895-4356 DOI: https://doi.org/10.1016/j.jclinepi.2011.08.012 Full text not available from this repository.

van Leeuwen, Nikki; Lingsma, Hester F; Perel, Pablo; Lecky, Fiona; Roozenbeek, Bob; Lu, Juan; Shakur, Haleema; Weir, James; Steyerberg, Ewout W; Maas, Andrew IR; +3 more... International Mission on Prognosis and Clinical Trial Design in; Corticosteroid Randomization After Significant Head Injury Trial; Trauma Audit and Research Network; (2012) Prognostic value of major extracranial injury in traumatic brain injury: an individual patient data meta-analysis in 39,274 patients. Neurosurgery, 70 (4). pp. 811-818. ISSN 0148-396X DOI: https://doi.org/10.1227/NEU.0b013e318235d640 Full text not available from this repository.

LSHTM; (2014) Living Library special - Saving the lives of trauma victims and using Big Data. [Podcast] http://soundcloud.com/lshtm/living-library-special...

LSHTM; (2016) Haleem Shakur: The WOMAN Trial. [Podcast] http://soundcloud.com/lshtm/haleem-shakur-the-woma...

Ageron, F-X D; (2021) Tranexamic acid in trauma care : who should be treated, when and where? PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04662122

Ageron, Francois-Xavier; Gayet-Ageron, Angele; Ker, Katharine; Coats, Timothy J; Shakur-Still, Haleema; Roberts, Ian; Antifibrinolytics Trials Collaboration; (2020) Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients. BRITISH JOURNAL OF ANAESTHESIA, 124 (6). pp. 676-683. ISSN 0007-0912 DOI: https://doi.org/10.1016/j.bja.2020.01.020

Ageron, Francois-Xavier; Shakur-Still, Haleema; Roberts, Ian; (2022) Effects of tranexamic acid treatment in severely and non-severely injured trauma patients. Transfusion, 62 Sup (Suppl). S151-S157. ISSN 0041-1132 DOI: https://doi.org/10.1111/trf.16954

Alvarado, JC; Dewan, Y; Elsayed, HF; Gogichaishvili, T; Gupta, S; Hunt, BJ; Iribhogbe, P; Izurieta, M; Khamis, H; Komolafe, EO; +10 more... Mejía Mantilla, JH; Miranda, J; Morales Uribe, CH; Olaomi, O; Olldashi, F; Perel, P; Ramana, PV; Ravi, RR; Roberts, IR; Shakur, H; (2012) Tranexamic acid in trauma: we need stronger global health policy. BMJ, 347 (4593). ISSN 0959-535X DOI: https://doi.org/10.1136/bmj.f4593

Andrews, Peter JD; Sinclair, Helen Louise; Battison, Claire G; Polderman, Kees H; Citerio, Giuseppe; Mascia, Luciana; Harris, Bridget A; Murray, Gordon D; Stocchetti, Nino; Menon, David K; +3 more... Shakur, Haleema; De Backer, Daniel; Eurotherm3235Trial collaborators; (2011) European society of intensive care medicine study of therapeutic hypothermia (32-35 °C) for intracranial pressure reduction after traumatic brain injury (the Eurotherm3235Trial). Trials, 12 (1). 8-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-12-8

Anti-fibrinolytics Trialists Collaborators – Obstetric Trialists; Ker, Katharine; Shakur-Still, Haleema; Sentilhes, Loïc; Pacheco, Luis D; Saade, George; Deneux-Tharaux, Catherine; Brenner, Amy; Mansukhani, Raoul; Ageron, François-Xavier; +4 more... Prowse, Danielle; Chaudhri, Rizwana; Olayemi, Oladapo; Roberts, Ian; (2023) Tranexamic acid for the prevention of postpartum bleeding: Protocol for a systematic review and individual patient data meta-analysis. Gates open research, 7. 3-. ISSN 2572-4754 DOI: https://doi.org/10.12688/gatesopenres.13747.2

Arribas, Monica; Roberts, Ian; Chaudhri, Rizwana; Geer, Amber; Prowse, Danielle; Lubeya, Mwansa Ketty; Kayani, Aasia; Javaid, Kiran; Grassin-Delyle, Stanislas; Shakur-Still, Haleema; (2021) WOMAN-PharmacoTXA trial: Study protocol for a randomised controlled trial to assess the pharmacokinetics and pharmacodynamics of intramuscular, intravenous and oral administration of tranexamic acid in women giving birth by caesarean section. Wellcome open research, 6. 157-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.16884.1

Beaumont, Danielle; Arribas, Monica; Frimley, Lauren; Balogun, Eni; Roberts, Ian; Shakur-Still, Haleema; (2019) Trial management: we need a cadre of high-class triallists to deliver the answers that patients need. Trials, 20 (1). 354-. DOI: https://doi.org/10.1186/s13063-019-3451-z

Brenner, A; (2023) Outcome measures in clinical trials of tranexamic acid for bleeding. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04670856

Brenner, Amy; Afolabi, Adefemi; Ahmad, Syed Masroor; Arribas, Monica; Chaudhri, Rizwana; Coats, Timothy; Cuzick, Jack; Gilmore, Ian; Hawkey, Christopher; Jairath, Vipul; +9 more... Javaid, Kiran; Kayani, Aasia; Mutti, Muttiullah; Nadeem, Muhammad Arif; Shakur-Still, Haleema; Stanworth, Simon; Veitch, Andrew; Roberts, Ian; HALT-IT Trial Collaborators; (2019) Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Trials, 20 (1). 467-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-019-3561-7

Brenner, Amy; Arribas, Monica; Cuzick, Jack; Jairath, Vipul; Stanworth, Simon; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian; (2018) Outcome measures in clinical trials of treatments for acute severe haemorrhage. Trials, 19 (1). 533-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-018-2900-4

Brenner, Amy; Belli, Antonio; Chaudhri, Rizwana; Coats, Timothy; Frimley, Lauren; Jamaluddin, Sabariah Faizah; Jooma, Rashid; Mansukhani, Raoul; Sandercock, Peter; Shakur-Still, Haleema; +3 more... Shokunbi, Temitayo; Roberts, Ian; CRASH-3 trial collaborators; (2020) Understanding the neuroprotective effect of tranexamic acid: an exploratory analysis of the CRASH-3 randomised trial. CRITICAL CARE, 24 (1). 560-. ISSN 1364-8535 DOI: https://doi.org/10.1186/s13054-020-03243-4

Brenner, Amy; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian; (2019) Tranexamic acid for post-partum haemorrhage: What, who and when. Best Practice & Research Clinical Obstetrics & Gynaecology, 61. pp. 66-74. ISSN 1521-6934 DOI: https://doi.org/10.1016/j.bpobgyn.2019.04.005

Brenner, Amy; Roberts, Ian; Balogun, Eni; Bello, Folasade Adenike; Chaudhri, Rizwana; Fleming, Charlotte; Javaid, Kiran; Kayani, Aasia; Lubeya, Mwansa Ketty; Mansukhani, Raoul; +4 more... Olayemi, Oladapo; Prowse, Danielle; Vwalika, Bellington; Shakur-Still, Haleema; (2022) Postpartum haemorrhage in anaemic women: assessing outcome measures for clinical trials. Trials, 23 (1). 220-. DOI: https://doi.org/10.1186/s13063-022-06140-z

Brenner, Amy; Shakur-Still, Haleema; Chaudhri, Rizwana; Fawole, Bukola; Arulkumaran, Sabaratnam; Roberts, Ian; WOMAN Trial Collaborators; (2018) The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial. BMC pregnancy and childbirth, 18 (1). 215-. ISSN 1471-2393 DOI: https://doi.org/10.1186/s12884-018-1855-5

Brenner, Amy; Shakur-Still, Haleema; Chaudhri, Rizwana; Muganyizi, Projestine; Olayemi, Oladapo; Arribas, Monica; Kayani, Aasia; Javid, Kiran; Bello, Adenike; Roberts, Ian; +1 more... I’M WOMAN Trial Collaborative Group; (2023) Tranexamic acid by the intramuscular or intravenous route for the prevention of postpartum haemorrhage in women at increased risk: a randomised placebo-controlled trial (I'M WOMAN). Trials, 24 (1). 782-. DOI: https://doi.org/10.1186/s13063-023-07687-1

CRASH-2 collaborators; Roberts, Ian; Shakur, Haleema; Afolabi, Adefemi; Brohi, Karim; Coats, Tim; Dewan, Yashbir; Gando, Satoshi; Guyatt, Gordon; Hunt, BJ; +4 more... Morales, Carlos; Perel, Pablo; Prieto-Merino, David; Woolley, Tom; (2011) The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet, 377 (9771). 1096-1101.e2. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(11)60278-X

Chung, CH; Freiberger, A; Kalkum, M; Luntz, SP; Shakur, H; Seiler, CM; (2006) CRASH2 in Germany [ISRCTN86750102]. Trials, 7 (1). 22-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-7-22

Coats, Tim; Hunt, Beverley; Roberts, Ian; Shakur, Haleema; (2005) Antifibrinolytic agents in traumatic hemorrhage: a large scale randomized controlled trial is needed. Croatian medical journal, 46 (1). pp. 146-147. ISSN 0353-9504 https://researchonline.lshtm.ac.uk/id/eprint/6403

Coats, Tim; Hunt, Beverly; Roberts, Ian; Shakur, Haleema; (2005) Antifibrinolytic agents in traumatic haemorrhage. PLoS medicine, 2 (3). e64-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.0020064

Cornelissen, Laura; Woodd, Susannah; Shakur-Still, Haleema; Fawole, Bukola; Noor, Shehla; Etuk, Saturday; Akintan, Adesina Lawrence; Chaudhri, Rizwana; Roberts, Ian; (2019) Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage. International journal of gynaecology and obstetrics, 146 (2). pp. 231-237. ISSN 0020-7292 DOI: https://doi.org/10.1002/ijgo.12860

Dallaku, Kastriot; Shakur, Haleema; Edwards, Phil; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Mansmann, Ulrich; (2017) Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation. Wellcome Open Research, 1. p. 30. DOI: https://doi.org/10.12688/wellcomeopenres.10105.1

Dallaku, Kastriot; Shakur, Haleema; Edwards, Phil; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Mansmann, Ulrich; (2016) Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation. Wellcome open research, 1. 30-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.10105.2

Dallaku, Kastriot; Shakur, Haleema; Roberts, Ian; Edwards, Phil; Beaumont, Danielle; Delius, Maria; Siegmund, Braun; Gliozheni, Orion; Tasha, Ilir; Cenameri, Saimir; +1 more... Mansmann, Ulrich; (2016) Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study. Scientific reports, 1. 29-. ISSN 2045-2322 DOI: https://doi.org/10.12688/wellcomeopenres.9964.1

Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich; (2019) No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. Wellcome open research, 4. 21-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14977.1

Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich; (2019) No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. Wellcome Open Research, 4. 21-. DOI: https://doi.org/10.12688/wellcomeopenres.14977.1

Dewan, Yashbir; Komolafe, Edward O; Mejía-Mantilla, Jorge H; Perel, Pablo; Roberts, Ian; Shakur, Haleema; CRASH-3 Collaborators; (2012) CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial. TRIALS, 13 (1). 87-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-13-87

Farrell, Barbara; Kenyon, Sara; Shakur, Haleema; (2010) Managing clinical trials. Trials, 11 (1). 78-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-11-78

Ferrer, Pili; Roberts, Ian; Sydenham, Emma; Blackhall, Karen; Shakur, Haleema; (2009) Anti-fibrinolytic agents in post partum haemorrhage: a systematic review. BMC pregnancy and childbirth, 9 (1). 29-. ISSN 1471-2393 DOI: https://doi.org/10.1186/1471-2393-9-29

Francis, David; Roberts, Ian; Elbourne, Diana R; Shakur, Haleema; Knight, Rosemary C; Garcia, Jo; Snowdon, Claire; Entwistle, Vikki A; McDonald, Alison M; Grant, Adrian M; +1 more... Campbell, Marion K; (2007) Marketing and clinical trials: a case study. Trials, 8 (1). 37-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-8-37

Gayet-Ageron, Angèle; Prieto-Merino, David; Ker, Katharine; Shakur, Haleema; Ageron, François-Xavier; Roberts, Ian; Antifibrinolytic Trials Collaboration; (2017) Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Lancet, 391 (10116). pp. 125-132. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(17)32455-8

Grassin-Delyle, Stanislas; Lamy, Elodie; Semeraro, Michaela; Runge, Iléana; Treluyer, Jean-Marc; Mansukhani, Raoul; Arribas, Monica; Roberts, Ian; Shakur-Still, Haleema; (2021) Clinical Validation of a Volumetric Absorptive Micro-Sampling Device for Pharmacokinetic Studies With Tranexamic Acid. Frontiers in pharmacology, 12. 764379-. ISSN 1663-9812 DOI: https://doi.org/10.3389/fphar.2021.764379

Grassin-Delyle, Stanislas; Semeraro, Michaela; Lamy, Elodie; Urien, Saïk; Runge, Iléana; Foissac, Frantz; Bouazza, Naim; Treluyer, Jean-Marc; Arribas, Monica; Roberts, Ian; +1 more... Shakur-Still, Haleema; (2022) Pharmacokinetics of tranexamic acid after intravenous, intramuscular, and oral routes: a prospective, randomised, crossover trial in healthy volunteers. British Journal of Anaesthesia, 128 (3). pp. 465-472. ISSN 0007-0912 DOI: https://doi.org/10.1016/j.bja.2021.10.054

Grassin-Delyle, Stanislas; Shakur-Still, Haleema; Picetti, Roberto; Frimley, Lauren; Jarman, Heather; Davenport, Ross; McGuinness, William; Moss, Phil; Pott, Jason; Tai, Nigel; +7 more... Lamy, Elodie; Urien, Saïk; Prowse, Danielle; Thayne, Andrew; Gilliam, Catherine; Pynn, Harvey; Roberts, Ian; (2020) Pharmacokinetics of intramuscular tranexamic acid in bleeding trauma patients: a clinical trial. British journal of anaesthesia, 126 (1). pp. 201-209. ISSN 0007-0912 DOI: https://doi.org/10.1016/j.bja.2020.07.058

Guerriero, Carla; Cairns, John; Jayaraman, Sudha; Roberts, Ian; Perel, Pablo; Shakur, Haleema; (2010) Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation. Cost effectiveness and resource allocation, 8 (1). 1-. ISSN 1478-7547 DOI: https://doi.org/10.1186/1478-7547-8-1

Guerriero, Carla; Cairns, John; Perel, Pablo; Shakur, Haleema; Roberts, Ian; CRASH 2 trial collaborators; (2011) Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial. PloS one, 6 (5). e18987-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0018987

Herrett, Emily; Williamson, Elizabeth; Beaumont, Danielle; Prowse, Danielle; Youssouf, Nabila; Brack, Kieran; Armitage, Jane; Goldacre, Ben; MacDonald, Thomas; Staa, Tjeerd van; +3 more... Roberts, Ian; Shakur-Still, Haleema; Smeeth, Liam; (2017) Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care. BMJ open, 7 (12). e016604-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-016604

Herrett, Emily; Williamson, Elizabeth; Brack, Kieran; Beaumont, Danielle; Perkins, Alexander; Thayne, Andrew; Shakur-Still, Haleema; Roberts, Ian; Prowse, Danielle; Goldacre, Ben; +11 more... van Staa, Tjeerd; MacDonald, Thomas M; Armitage, Jane; Wimborne, Jon; Melrose, Paula; Singh, Jayshireen; Brooks, Lucy; Moore, Michael; Hoffman, Maurice; Smeeth, Liam; StatinWISE Trial Group; (2021) Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials. British Medical Journal, 372. n135-. ISSN 1756-1833 DOI: https://doi.org/10.1136/bmj.n135

Herrett, Emily; Williamson, Elizabeth; Brack, Kieran; Beaumont, Danielle; Perkins, Alexander; Thayne, Andrew; Shakur-Still, Haleema; Roberts, Ian; Prowse, Danielle; Goldacre, Ben; +10 more... van Staa, Tjeerd; MacDonald, Thomas M; Armitage, Jane; Wimborne, Jon; Melrose, Paula; Singh, Jayshireen; Brooks, Lucy; Moore, Michael; Hoffman, Maurice; Smeeth, Liam; (2021) Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials. BMJ, 372. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.n135

Herrett, Emily; Williamson, Elizabeth; Brack, Kieran; Perkins, Alexander; Thayne, Andrew; Shakur-Still, Haleema; Roberts, Ian; Prowse, Danielle; Beaumont, Danielle; Jamal, Zahra; +7 more... Goldacre, Ben; van Staa, Tjeerd; MacDonald, Thomas M; Armitage, Jane; Moore, Michael; Hoffman, Maurice; Smeeth, Liam; (2021) The effect of statins on muscle symptoms in primary care: the StatinWISE series of 200 N-of-1 RCTs. Health technology assessment (Winchester, England), 25 (16). pp. 1-62. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25160

Hibbs, Stephen P; Roberts, Ian; Shakur-Still, Haleema; Hunt, Beverley J; (2018) Post-partum haemorrhage and tranexamic acid: a global issue. British journal of haematology, 180 (6). pp. 799-807. ISSN 0007-1048 DOI: https://doi.org/10.1111/bjh.15073

Hough, Amy; Shakur-Still, Haleema; Roberts, Ian; Koukounari, Artemis; Lawn, Joy E; WOMAN Trial Collaborators; (2020) Stillbirths and neonatal deaths among 18 942 women with postpartum hemorrhage: Analysis of perinatal outcomes in the WOMAN trial. INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS (1). ISSN 0020-7292 DOI: https://doi.org/10.1002/ijgo.13413

Houghton, G; Kingdon, C; Dower, M; Shakur-Still, H; Alfirevic, Z; (2018) What women think about consent to research at the time of an obstetric emergency: a qualitative study of the views of a cohort of World Maternal Antifibrinolytic Trial participants. BJOG, 125 (13). pp. 1744-1753. ISSN 1470-0328 DOI: https://doi.org/10.1111/1471-0528.15333

Huque, Sumaya; Roberts, Ian; Fawole, Bukola; Chaudhri, Rizwana; Arulkumaran, Sabaratnam; Shakur-Still, Haleema; (2018) Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial. BMC pregnancy and childbirth, 18 (1). 186-. ISSN 1471-2393 DOI: https://doi.org/10.1186/s12884-018-1829-7

Kane, Zoe; Picetti, Roberto; Wilby, Alison; Standing, Joseph F; Grassin-Delyle, Stanislas; Roberts, Ian; Shakur-Still, Haleema; (2021) Physiologically based modelling of tranexamic acid pharmacokinetics following intravenous, intramuscular, sub-cutaneous and oral administration in healthy volunteers. European Journal of Pharmaceutical Sciences, 164. 105893-. ISSN 0928-0987 DOI: https://doi.org/10.1016/j.ejps.2021.105893

Ker, K; Shakur, H; Roberts, I; (2016) Does tranexamic acid prevent postpartum haemorrhage? A systematic review of randomised controlled trials. BJOG, 123 (11). pp. 1745-52. ISSN 1470-0328 DOI: https://doi.org/10.1111/1471-0528.14267

Ker, K; Tansley, G; Beecher, D; Perner, A; Shakur, H; Harris, T; Roberts, I; (2015) Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease. The Cochrane database of systematic reviews, 2. CD011386. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD011386.pub2

Ker, Katharine; Edwards, Phil; Perel, Pablo; Shakur, Haleema; Roberts, Ian; (2012) Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis. BMJ (Clinical research ed), 344 (may17). e3054-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.e3054

Ker, Katharine; Kiriya, Junko; Perel, Pablo; Edwards, Phil; Shakur, Haleema; Roberts, Ian; (2012) Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial. BMC emergency medicine, 12 (1). 3-. ISSN 1471-227X DOI: https://doi.org/10.1186/1471-227X-12-3

Ker, Katharine; Mansukhani, Raoul; Shakur-Still, Haleema; Arribas, Monica; Beaumont, Danielle; Roberts, Ian; (2023) Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients. BMJ Open, 13 (2). e059982-. DOI: https://doi.org/10.1136/bmjopen-2021-059982

Ker, Katharine; Roberts, Ian; Chaudhri, Rizwana; Fawole, Bukola; Beaumont, Danielle; Balogun, Eni; Prowse, Danielle; Pepple, Tracey; Javaid, Kiran; Kayani, Aasia; +4 more... Arulkumaran, Sabaratnam; Bates, Imelda; Shakur-Still, Haleema; WOMAN-2 trial collaborators; (2018) Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial. Trials, 19 (1). 712-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-018-3081-x

Ker, Katharine; Roberts, Ian; Shakur, Haleema; Coats, Tim J; (2015) Antifibrinolytic drugs for acute traumatic injury. The Cochrane database of systematic reviews, 2015 (5). CD004896-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD004896.pub4

Ker, Katharine; Tansley, Gavin; Beecher, Deirdre; Perner, Anders; Shakur, Haleema; Harris, Tim; Roberts, Ian; (2015) Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease. The Cochrane database of systematic reviews, 2015 (2). CD011386-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD011386.pub2

Kolin, David A; Shakur-Still, Haleema; Bello, Adenike; Chaudhri, Rizwana; Bates, Imelda; Roberts, Ian; (2020) Risk factors for blood transfusion in traumatic and postpartum hemorrhage patients: Analysis of the CRASH-2 and WOMAN trials. PloS one, 15 (6). e0233274-. DOI: https://doi.org/10.1371/journal.pone.0233274

Lamy, Elodie; Runge, Ileana; Roberts, Ian; Shakur-Still, Haleema; Grassin-Delyle, Stanislas; (2020) Tranexamic acid quantification in human whole blood using liquid samples or volumetric absorptive microsampling devices. Bioanalysis, 12 (12). pp. 835-844. ISSN 1757-6180 DOI: https://doi.org/10.4155/bio-2020-0088

Li, Bernadette; Miners, Alec; Shakur, Haleema; Roberts, Ian; WOMAN Trial Collaborators; (2018) Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial. The Lancet Global health, 6 (2). e222-e228. ISSN 2214-109X DOI: https://doi.org/10.1016/S2214-109X(17)30467-9

MRC CRASH Trial Collaborators; Perel, Pablo; Arango, Miguel; Clayton, Tim; Edwards, Phil; Komolafe, Edward; Poccock, Stuart; Roberts, Ian; Shakur, Haleema; Steyerberg, Ewout; +1 more... Yutthakasemsunt, Surakrant; (2008) Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients. BMJ, 336 (7641). pp. 425-429. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.39461.643438.25

Mahmood, A; (2020) Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a randomised trial. PhD (research paper style) thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04659849

Mahmood, Abda; Needham, Kelly; Shakur-Still, Haleema; Harris, Tim; Jamaluddin, Sabariah Faizah; Davies, David; Belli, Antonio; Mohamed, Fatahul Laham; Leech, Caroline; Lotfi, Hamzah Mohd; +8 more... Moss, Phil; Lecky, Fiona; Hopkins, Philip; Wong, Darin; Boyle, Adrian; Wilson, Mark; Darwent, Melanie; Roberts, Ian; (2020) Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a pre-planned substudy in a sample of CRASH-3 trial patients. Emergency medicine journal : EMJ, 38 (4). pp. 270-278. ISSN 1472-0205 DOI: https://doi.org/10.1136/emermed-2020-210424

Mahmood, Abda; Roberts, Ian; Shakur, Haleema; (2017) A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS]). Trials, 18 (1). 330-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-017-2073-6

Mahmood, Abda; Roberts, Ian; Shakur-Still, Haleema; (2019) A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan. Wellcome open research, 3. 99-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14731.3

Mansukhani, Raoul; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Frimley, Lauren; Faizah Jamaluddin, Sabariah; Jooma, Rashid; Shakur-Still, Haleema; Shokunbi, Temitayo; Roberts, Ian; (2021) Effect of early tranexamic acid treatment on fatigue in patients with mild traumatic brain injury: data from the CRASH-3 clinical trial. Wellcome Open Research, 6. p. 346. DOI: https://doi.org/10.12688/wellcomeopenres.17421.1

Mansukhani, Raoul; Frimley, Lauren; Shakur-Still, Haleema; Sharples, Linda; Roberts, Ian; (2020) Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results. Trials, 21 (1). 681-. DOI: https://doi.org/10.1186/s13063-020-04623-5

McDonald, Alison M; Treweek, Shaun; Shakur, Haleema; Free, Caroline; Knight, Rosemary; Speed, Chris; Campbell, Marion K; (2011) Using a business model approach and marketing techniques for recruitment to clinical trials. Trials, 12 (1). 74-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-12-74

Miller, Lori; Chaudhri, Shahana; Beaumont, Danielle; Kayani, Aasia; Javid, Kiran; Chaudhri, Rizwana; Edwards, Phil; Brenner, Amy; Roberts, Ian; Shakur-Still, Haleema; (2021) Development of a patient reported outcome questionnaire to measure the impact of postpartum blood loss in women with moderate and severe anaemia: A study using a multi-faceted approach. Wellcome Open Research, 4. p. 85. DOI: https://doi.org/10.12688/wellcomeopenres.15245.1

Miller, Lori; Chaudhri, Shahana; Beaumont, Danielle; Kayani, Aasia; Javid, Kiran; Chaudhri, Rizwana; Edwards, Phil; Brenner, Amy; Roberts, Ian; Shakur-Still, Haleema; (2021) Development of a patient reported outcome questionnaire to measure the impact of postpartum blood loss in women with moderate and severe anaemia: A study using a multi-faceted approach. Wellcome Open Research, 4. p. 85. DOI: https://doi.org/10.12688/wellcomeopenres.15245.2

Mousa, Hatem A; Blum, Jennifer; Abou El Senoun, Ghada; Shakur, Haleema; Alfirevic, Zarko; (2014) Treatment for primary postpartum haemorrhage. The Cochrane database of systematic reviews, 2014 (2). CD003249-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD003249.pub3

Ngo, Thoai D; Park, Min Hae; Shakur, Haleema; Free, Caroline; (2011) Comparative effectiveness, safety and acceptability of medical abortion at home and in a clinic: a systematic review. Bulletin of the World Health Organization, 89 (5). pp. 360-370. ISSN 0042-9686 DOI: https://doi.org/10.2471/BLT.10.084046

Nutbeam, Tim; Roberts, Ian; Weekes, Lauren; Shakur-Still, Haleema; Brenner, Amy; Ageron, Francois-Xavier; (2022) Use of tranexamic acid in major trauma: a sex-disaggregated analysis of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2 and CRASH-3) trials and UK trauma registry (Trauma and Audit Research Network) data. British Journal of Anaesthesia, 129 (2). pp. 191-199. ISSN 0007-0912 DOI: https://doi.org/10.1016/j.bja.2022.03.032

Perel, P; Al-Shahi Salman, R; Kawahara, T; Morris, Z; Prieto-Merino, D; Roberts, I; Sandercock, P; Shakur, H; Wardlaw, J; (2012) CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury--a nested randomised, placebo-controlled trial. Health technology assessment (Winchester, England), 16 (13). iii-54. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta16130

Perel, Pablo; Edwards, Phil; Shakur, Haleema; Roberts, Ian; (2008) Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury. BMC medical research methodology, 8 (1). 72-. ISSN 1471-2288 DOI: https://doi.org/10.1186/1471-2288-8-72

Perel, Pablo; Prieto-Merino, David; Shakur, Haleema; Clayton, Tim; Lecky, Fiona; Bouamra, Omar; Russell, Rob; Faulkner, Mark; Steyerberg, Ewout W; Roberts, Ian; (2012) Predicting early death in patients with traumatic bleeding: development and validation of prognostic model. BMJ (Clinical research ed), 345 (aug15). e5166-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.e5166

Perel, Pablo; Roberts, Ian; Shakur, Haleema; Thinkhamrop, Bandit; Phuenpathom, Nakornchai; Yutthakasemsunt, Surakrant; (2010) Haemostatic drugs for traumatic brain injury. The Cochrane database of systematic reviews, 1 (1). CD007877-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD007877.pub2

Perel, Pablo; Salman, RAS; Kawahara, T; Morris, Z; Prieto-merino, David; Roberts, Ian; Sandercock, P; Shakur-still, Haleema; Wardlaw, J; (2012) CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury - a nested, randomised, placebo-controlled trial. Health technology assessment (Winchester, England), 16 (13). 1-+. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta16130

Picetti, Roberto; Miller, Lori; Shakur-Still, Haleema; Pepple, Tracey; Beaumont, Danielle; Balogun, Eni; Asonganyi, Etienne; Chaudhri, Rizwana; El-Sheikh, Mohamed; Vwalika, Bellington; +2 more... Arulkumaran, Sabaratnam; Roberts, Ian; (2020) The WOMAN Trial: Clinical and Contextual Factors Surrounding the Deaths of 483 Women Following Post-Partum Hemorrhage in Developing Countries. Obstetrical & Gynecological Survey, 75 (12). pp. 723-725. ISSN 0029-7828 DOI: https://doi.org/10.1097/01.ogx.0000723728.09046.e3

Picetti, Roberto; Miller, Lori; Shakur-Still, Haleema; Pepple, Tracey; Beaumont, Danielle; Balogun, Eni; Asonganyi, Etienne; Chaudhri, Rizwana; El-Sheikh, Mohamed; Vwalika, Bellington; +3 more... Arulkumaran, Sabaratnam; Roberts, Ian; WOMAN trial collaborators; (2020) The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries. BMC Pregnancy and Childbirth, 20 (1). 409-. ISSN 1471-2393 DOI: https://doi.org/10.1186/s12884-020-03091-8

Picetti, Roberto; Shakur-Still, Haleema; Medcalf, Robert L; Standing, Joseph F; Roberts, Ian; (2018) What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies. Blood coagulation & fibrinolysis, 30 (1). pp. 1-10. ISSN 0957-5235 DOI: https://doi.org/10.1097/MBC.0000000000000789

Roberts, I; Shakur, H; Coats, T; Hunt, B; Balogun, E; Barnetson, L; Cook, L; Kawahara, T; Perel, P; Prieto-Merino, D; +3 more... Ramos, M; Cairns, J; Guerriero, C; (2013) The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health technology assessment (Winchester, England), 17 (10). pp. 1-79. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta17100

Roberts, I; Shakur, H; Coats, T; Hunt, B; Balogun, E; Barnetson, L; Cook, L; Kawahara, T; Perel, P; Prieto-Merino, D; +3 more... Ramos, M; Cairns, J; Guerriero, C; (2013) The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health technology assessment (Winchester, England), 17 (10). pp. 1-79. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta17240

Roberts, I; Shakur, H; Ker, K; Coats, T; CRASH-2 Trial collaborators; (2011) Antifibrinolytic drugs for acute traumatic injury. The Cochrane database of systematic reviews, 1 (1). CD004896. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD004896.pub3

Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur, Haleema; (2018) Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Wellcome Open Research, 3. p. 86. DOI: https://doi.org/10.12688/wellcomeopenres.14700.1

Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur, Haleema; (2018) Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Wellcome Open Research, 3. p. 86. DOI: https://doi.org/10.12688/wellcomeopenres.14700.2

Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur, Haleema; +1 more... CRASH-3 trial collaborators; (2018) Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Wellcome open research, 3. 86-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14700.2

Roberts, Ian; Brenner, Amy; Shakur-Still, Haleema; (2021) Tranexamic Acid Treatment for Trauma Victims. Seminars in Thrombosis and Hemostasis, 47 (5). pp. 520-526. ISSN 0094-6176 DOI: https://doi.org/10.1055/s-0041-1725097

Roberts, Ian; Brenner, Amy; Shakur-Still, Haleema; (2022) Tranexamic acid for bleeding: Much more than a treatment for postpartum hemorrhage. American Journal of Obstetrics & Gynecology, 5 (2S). 100722-. ISSN 2589-9333 DOI: https://doi.org/10.1016/j.ajogmf.2022.100722

Roberts, Ian; Coats, Timothy; Edwards, Phil; Gilmore, Ian; Jairath, Vipul; Ker, Katharine; Manno, Daniela; Shakur, Haleema; Stanworth, Simon; Veitch, Andrew; (2014) HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial. Trials, 15 (1). 450-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-15-450

Roberts, Ian; Edwards, Phil; Prieto, David; Joshi, Miland; Mahmood, Abda; Ker, Katharine; Shakur, Haleema; (2017) Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. Trials, 18 (1). 48-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-016-1750-1

Roberts, Ian; Perel, Pablo; Prieto-Merino, David; Shakur, Haleema; Coats, Tim; Hunt, Beverley J; Lecky, Fiona; Brohi, Karim; Willett, Keith; CRASH-2 Collaborators; (2012) Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial. BMJ (Clinical research ed), 345 (sep11). e5839-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.e5839

Roberts, Ian; Shakur, Haleema; Edwards, Phil; Yates, David; Sandercock, Peter; (2005) Trauma care research and the war on uncertainty. BMJ, 331 (7525). pp. 1094-1096. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.331.7525.1094

Roberts, Ian; Shakur, Haleema; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris O; Olutogun, Tolulase; +2 more... Hunt, Beverley J; Huque, Sumaya; (2018) Haematological and fibrinolytic status of Nigerian women with post-partum haemorrhage. BMC pregnancy and childbirth, 18 (1). 143-. ISSN 1471-2393 DOI: https://doi.org/10.1186/s12884-018-1794-1

Roberts, Ian; Shakur, Haleema; Ker, Katharine; Coats, Tim; CRASH-2 Trial collaborators; (2012) Antifibrinolytic drugs for acute traumatic injury. The Cochrane database of systematic reviews, 129 (1). CD004896-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD004896.pub3

Roberts, Ian; Shakur-Still, Haleema; Aeron-Thomas, Amy; Beaumont, Danielle; Belli, Antonio; Brenner, Amy; Cargill, Madeleine; Chaudhri, Rizwana; Douglas, Nicolas; Frimley, Lauren; +10 more... Gilliam, Catherine; Geer, Amber; Jamal, Zahra; Jooma, Rashid; Mansukhani, Raoul; Miners, Alec; Pott, Jason; Prowse, Danielle; Shokunbi, Temitayo; Williams, Jack; (2021) Tranexamic acid to reduce head injury death in people with traumatic brain injury: the CRASH-3 international RCT. Health technology assessment (Winchester, England), 25 (26). pp. 1-76. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25260

Roberts, Ian; Shakur-Still, Haleema; Afolabi, Adefemi; Akere, Adegboyega; Arribas, Monica; Austin, Emma; Bal, Kiran; Bazeer, Nuha; Beaumont, Danielle; Brenner, Amy; +20 more... Carrington, Laura; Chaudhri, Rizwana; Coats, Timothy; Gilmore, Ian; Halligan, Kenneth; Hussain, Irshad; Jairath, Vipul; Javaid, Kiran; Kayani, Aasia; Lisman, Ton; Mansukhani, Raoul; Miners, Alec; Mutti, Muttiullah; Nadeem, Muhammad Arif; Pollok, Richard; Prowse, Danielle; Simmons, Jonathan; Stanworth, Simon; Veitch, Andrew; Williams, Jack; (2021) A high-dose 24-hour tranexamic acid infusion for the treatment of significant gastrointestinal bleeding: HALT-IT RCT. Health technology assessment (Winchester, England), 25 (58). pp. 1-86. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25580

Shakur, Haleema; Andrews, Peter; Asser, Toomas; Balica, Laura; Boeriu, Cristian; Quintero, Juan Diego Ciro; Dewan, Yashbir; Druwé, Patrick; Fletcher, Olivia; Frost, Chris; +10 more... Hartzenberg, Bennie; Mantilla, Jorge Mejia; Murillo-Cabezas, Francisco; Pachl, Jan; Ravi, Ramalingam R; Rätsep, Indrek; Sampaio, Cristina; Singh, Manmohan; Svoboda, Petr; Roberts, Ian; (2009) The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury. Trials, 10 (1). 109-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-10-109

Shakur, Haleema; Beaumont, Danielle; Pavord, Sue; Gayet-Ageron, Angele; Ker, Katharine; Mousa, Hatem A; (2018) Antifibrinolytic drugs for treating primary postpartum haemorrhage. The Cochrane database of systematic reviews, 2 (2). CD012964-CD012964. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD012964

Shakur, Haleema; Beaumont, Danielle; Pavord, Sue; Gayet-Ageron, Angele; Ker, Katharine; Mousa, Hatem A; (2018) Antifibrinolytic drugs for treating primary postpartum hemorrhage. Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 32 (3). pp. 203-205. ISSN 1137-6821 DOI: https://doi.org/10.1002/14651858.CD012964

Shakur, Haleema; Elbourne, Diana; Gülmezoglu, Metin; Alfirevic, Zarko; Ronsmans, Carine; Allen, Elizabeth; Roberts, Ian; (2010) The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial. Trials, 11 (1). 40-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-11-40

Shakur, Haleema; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris O; Huque, Sumaya; Gregg, Meghann; +1 more... Roberts, Ian; (2016) Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial. Wellcome open research, 1. 31-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.10383.1

Shakur, Haleema; Roberts, Ian; Barnetson, Lin; Coats, Tim; (2007) Clinical trials in emergency situations. BMJ (Clinical research ed), 334 (7586). pp. 165-166. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.39097.582130.80

Shakur, Haleema; Roberts, Ian; Edwards, Philip; Elbourne, Diana; Alfirevic, Zarko; Ronsmans, Carine; (2016) The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial. Trials, 17 (1). 249-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-016-1332-2

Shakur-Still, Haleema; Grassin-Delyle, Stanislas; Muhunthan, Kopalasuntharam; Ahmadzia, Homa K; Faraoni, David; Arribas, Monica; Roberts, Ian; (2022) Alternative routes to intravenous tranexamic acid for postpartum hemorrhage: A systematic search and narrative review. International journal of gynecology & obstetrics, 158 Su (Suppl ). pp. 40-45. ISSN 0020-7292 DOI: https://doi.org/10.1002/ijgo.14201

Shakur-Still, Haleema; Roberts, Ian; (2018) Finding Better Ways to Prevent Postpartum Hemorrhage. The New England journal of medicine, 379 (8). pp. 790-792. ISSN 0028-4793 DOI: https://doi.org/10.1056/NEJMe1808500

Shakur-Still, Haleema; Roberts, Ian; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo O; Bello, Adenike; Huque, Sumaya; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris; +8 more... Okunade, Olujide A; Olutogun, Tolulase; Adetayo, Cecilia O; Dallaku, Kastriot; Mansmann, Ulrich; Hunt, Beverley J; Pepple, Tracey; Balogun, Eni; (2018) Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial. Wellcome open research, 3. 100-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14722.1

Shakur-Still, Haleema; Roberts, Ian; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Huque, Sumaya; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris; +8 more... Okunade, Olujide; Olutogun, Tolulase; Adetayo, Cecilia; Dallaku, Kastriot; Mansmann, Ulrich; Hunt, Beverley; Pepple, Tracey; Balogun, Eni; (2018) Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial. Wellcome Open Research, 3 (100). 14722-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14722.1

Shakur-Still, Haleema; Roberts, Ian; Grassin-Delyle, Stanislas; Chaudhri, Rizwana; Geer, Amber; Arribas, Monica; Lamy, Elodie; Mansukhani, Raoul; Lubeya, Mwansa Ketty; Javaid, Kiran; +11 more... Kayani, Aasia; Israr, Naila; Mazhar, Syeda Batool; Urien, Saïk; Bouazza, Naïm; Foissac, Frantz; Prowse, Danielle; Carrington, Laura; Barrow, Collette; Onandia, Julio Gil; Balogun, Eni; (2023) Alternative routes for tranexamic acid treatment in obstetric bleeding (WOMAN-PharmacoTXA trial): a randomised trial and pharmacological study in caesarean section births. BJOG : an international journal of obstetrics and gynaecology, 130 (10). pp. 1177-1186. ISSN 1470-0328 DOI: https://doi.org/10.1111/1471-0528.17455

Williams, Jack; Roberts, Ian; Shakur-Still, Haleema; Lecky, Fiona E; Chaudhri, Rizwana; Miners, Alec; (2020) Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach. BMJ GLOBAL HEALTH, 5 (9). e002716-e002716. ISSN 2059-7908 DOI: https://doi.org/10.1136/bmjgh-2020-002716

Williams, Jack; Ker, Katharine; Roberts, Ian; Shakur-Still, Haleema; Miners, Alec; (2022) A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury. Trials, 23 (1). 370-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-022-06244-6 Item availability may be restricted.

Williams, Jack; Ker, Katharine; Roberts, Ian; Shakur-Still, Haleema; Miners, Alec; (2022) A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury. Trials, 23 (1). 370-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-022-06244-6 Item availability may be restricted.