Items where Author or Contributor is "Whittaker, John"
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Number of items: 151.
2020
Tvermosegaard, KT;
(2020)
Computational Methods for D-optimal Design in Nonlinear Mixed Effects Models.
PhD thesis, London School of Hygiene & Tropical Medicine.
DOI: https://doi.org/10.17037/PUBS.04657431
2016
Charoen, Pimphen;
Nitsch, Dorothea;
Engmann, Jorgen;
Shah, Tina;
White, Jonathan;
Zabaneh, Delilah;
Jefferis, Barbara;
Wannamethee, Goya;
Whincup, Peter;
Mulick Cassidy, Amy;
+14 more...
Gaunt, Tom;
Day, Ian;
McLachlan, Stela;
Price, Jacqueline;
Kumari, Meena;
Kivimaki, Mika;
Brunner, Eric;
Langenberg, Claudia;
Ben-Shlomo, Yoav;
Hingorani, Aroon;
Whittaker, John;
Pablo Casas, Juan;
Dudbridge, Frank;
UCLEB Consortium;
(2016)
Mendelian Randomisation study of the influence of eGFR on coronary heart disease.
Scientific reports, 6 (1).
28514-.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep28514
Swerdlow, Daniel I;
Kuchenbaecker, Karoline B;
Shah, Sonia;
Sofat, Reecha;
Holmes, Michael V;
White, Jon;
Mindell, Jennifer S;
Kivimaki, Mika;
Brunner, Eric J;
Whittaker, John C;
+2 more...
Casas, Juan P;
Hingorani, Aroon D;
(2016)
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.
International journal of epidemiology, 45 (5).
pp. 1600-1616.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyw088
2015
Moore, Gudrun E;
Ishida, Miho;
Demetriou, Charalambos;
Al-Olabi, Lara;
Leon, Lydia J;
Thomas, Anna C;
Abu-Amero, Sayeda;
Frost, Jennifer M;
Stafford, Jaime L;
Chaoqun, Yao;
+12 more...
Duncan, Andrew J;
Baigel, Rachel;
Brimioulle, Marina;
Iglesias-Platas, Isabel;
Apostolidou, Sophia;
Aggarwal, Reena;
Whittaker, John C;
Syngelaki, Argyro;
Nicolaides, Kypros H;
Regan, Lesley;
Monk, David;
Stanier, Philip;
(2015)
The role and interaction of imprinted genes in human fetal growth.
Philosophical transactions of the Royal Society of London Series B, Biological sciences, 370 (1663).
20140074-.
ISSN 0962-8436
DOI: https://doi.org/10.1098/rstb.2014.0074
Nelson, Matthew R;
Tipney, Hannah;
Painter, Jeffery L;
Shen, Judong;
Nicoletti, Paola;
Shen, Yufeng;
Floratos, Aris;
Sham, Pak Chung;
Li, Mulin Jun;
Wang, Junwen;
+3 more...
Cardon, Lon R;
Whittaker, John C;
Sanseau, Philippe;
(2015)
The support of human genetic evidence for approved drug indications.
Nature genetics, 47 (8).
pp. 856-860.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng.3314
Full text not available from this repository.
Nüesch, Eveline;
Dale, Caroline;
Palmer, Tom M;
White, Jon;
Keating, Brendan J;
van Iperen, Erik Pa;
Goel, Anuj;
Padmanabhan, Sandosh;
Asselbergs, Folkert W;
EPIC-Netherland Investigators;
+71 more...
Verschuren, WM;
Wijmenga, C;
Van der Schouw, YT;
Onland-Moret, NC;
Lange, Leslie A;
Hovingh, GK;
Sivapalaratnam, Suthesh;
Morris, Richard W;
Whincup, Peter H;
Wannamethe, Goya S;
Gaunt, Tom R;
Ebrahim, Shah;
Steel, Laura;
Nair, Nikhil;
Reiner, Alexander P;
Kooperberg, Charles;
Wilson, James F;
Bolton, Jennifer L;
McLachlan, Stela;
Price, Jacqueline F;
Strachan, Mark Wj;
Robertson, Christine M;
Kleber, Marcus E;
Delgado, Graciela;
März, Winfried;
Melander, Olle;
Dominiczak, Anna F;
Farrall, Martin;
Watkins, Hugh;
Leusink, Maarten;
Maitland-van der Zee, Anke H;
de Groot, Mark Ch;
Dudbridge, Frank;
Hingorani, Aroon;
Ben-Shlomo, Yoav;
Lawlor, Debbie A;
UCLEB Investigators;
Amuzu, A;
Caufield, M;
Cavadino, A;
Cooper, J;
Davies, TL;
IN Day;
Drenos, F;
Engmann, J;
Finan, C;
Giambartolomei, C;
Hardy, R;
Humphries, SE;
Hypponen, E;
Kivimaki, M;
Kuh, D;
Kumari, M;
Ong, K;
Plagnol, V;
Power, C;
Richards, M;
Shah, S;
Shah, T;
Sofat, R;
Talmud, PJ;
Wareham, N;
Warren, H;
Whittaker, JC;
Wong, A;
Zabaneh, D;
Davey Smith, George;
Wells, Jonathan C;
Leon, David A;
Holmes, Michael V;
Casas, Juan P;
(2015)
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.
International journal of epidemiology, 45 (6).
pp. 1927-1937.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyv074
Xu, C-F;
Johnson, T;
Garcia-Donas, J;
Choueiri, TK;
Sternberg, CN;
Davis, ID;
Bing, N;
Deen, KC;
Xue, Z;
McCann, L;
+6 more...
Esteban, E;
Whittaker, JC;
Spraggs, CF;
Rodríguez-Antona, C;
Pandite, LN;
Motzer, RJ;
(2015)
IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.
British journal of cancer, 112 (7).
pp. 1190-1198.
ISSN 0007-0920
DOI: https://doi.org/10.1038/bjc.2015.64
2014
Futema, Marta;
Shah, Sonia;
Cooper, Jackie A;
Li, KaWah;
Whittall, Ros A;
Sharifi, Mahtab;
Goldberg, Olivia;
Drogari, Euridiki;
Mollaki, Vasiliki;
Wiegman, Albert;
+16 more...
Defesche, Joep;
D'Agostino, Maria N;
D'Angelo, Antonietta;
Rubba, Paolo;
Fortunato, Giuliana;
Waluś-Miarka, Małgorzata;
Hegele, Robert A;
Aderayo Bamimore, Mary;
Durst, Ronen;
Leitersdorf, Eran;
Mulder, Monique T;
Roeters van Lennep, Jeanine E;
Sijbrands, Eric JG;
Whittaker, John C;
Talmud, Philippa J;
Humphries, Steve E;
(2014)
Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries.
Clinical chemistry, 61 (1).
pp. 231-238.
ISSN 0009-9147
DOI: https://doi.org/10.1373/clinchem.2014.231365
Full text not available from this repository.
Holmes, Michael V;
Dale, Caroline E;
Zuccolo, Luisa;
Silverwood, Richard J;
Guo, Yiran;
Ye, Zheng;
Prieto-Merino, David;
Dehghan, Abbas;
Trompet, Stella;
Wong, Andrew;
+146 more...
Cavadino, Alana;
Drogan, Dagmar;
Padmanabhan, Sandosh;
Li, Shanshan;
Yesupriya, Ajay;
Leusink, Maarten;
Sundstrom, Johan;
Hubacek, Jaroslav A;
Pikhart, Hynek;
Swerdlow, Daniel I;
Panayiotou, Andrie G;
Borinskaya, Svetlana A;
Finan, Chris;
Shah, Sonia;
Kuchenbaecker, Karoline B;
Shah, Tina;
Engmann, Jorgen;
Folkersen, Lasse;
Eriksson, Per;
Ricceri, Fulvio;
Melander, Olle;
Sacerdote, Carlotta;
Gamble, Dale M;
Rayaprolu, Sruti;
Ross, Owen A;
McLachlan, Stela;
Vikhireva, Olga;
Sluijs, Ivonne;
Scott, Robert A;
Adamkova, Vera;
Flicker, Leon;
Bockxmeer, Frank M van;
Power, Christine;
Marques-Vidal, Pedro;
Meade, Tom;
Marmot, Michael G;
Ferro, Jose M;
Paulos-Pinheiro, Sofia;
Humphries, Steve E;
Talmud, Philippa J;
Mateo Leach, Irene;
Verweij, Niek;
Linneberg, Allan;
Skaaby, Tea;
Doevendans, Pieter A;
Cramer, Maarten J;
van der Harst, Pim;
Klungel, Olaf H;
Dowling, Nicole F;
Dominiczak, Anna F;
Kumari, Meena;
Nicolaides, Andrew N;
Weikert, Cornelia;
Boeing, Heiner;
Ebrahim, Shah;
Gaunt, Tom R;
Price, Jackie F;
Lannfelt, Lars;
Peasey, Anne;
Kubinova, Ruzena;
Pajak, Andrzej;
Malyutina, Sofia;
Voevoda, Mikhail I;
Tamosiunas, Abdonas;
Maitland-van der Zee, Anke H;
Norman, Paul E;
Hankey, Graeme J;
Bergmann, Manuela M;
Hofman, Albert;
Franco, Oscar H;
Cooper, Jackie;
Palmen, Jutta;
Spiering, Wilko;
de Jong, Pim A;
Kuh, Diana;
Hardy, Rebecca;
Uitterlinden, Andre G;
Ikram, M Arfan;
Ford, Ian;
Hyppönen, Elina;
Almeida, Osvaldo P;
Wareham, Nicholas J;
Khaw, Kay-Tee;
Hamsten, Anders;
Husemoen, Lise Lotte N;
Tjønneland, Anne;
Tolstrup, Janne S;
Rimm, Eric;
Beulens, Joline WJ;
Verschuren, WM Monique;
Onland-Moret, N Charlotte;
Hofker, Marten H;
Wannamethee, S Goya;
Whincup, Peter H;
Morris, Richard;
Vicente, Astrid M;
Watkins, Hugh;
Farrall, Martin;
Jukema, J Wouter;
Meschia, James;
Cupples, L Adrienne;
Sharp, Stephen J;
Fornage, Myriam;
Kooperberg, Charles;
LaCroix, Andrea Z;
Dai, James Y;
Lanktree, Matthew B;
Siscovick, David S;
Jorgenson, Eric;
Spring, Bonnie;
Coresh, Josef;
Li, Yun R;
Buxbaum, Sarah G;
Schreiner, Pamela J;
Ellison, R Curtis;
Tsai, Michael Y;
Patel, Sanjay R;
Redline, Susan;
Johnson, Andrew D;
Hoogeveen, Ron C;
Hakonarson, Hakon;
Rotter, Jerome I;
Boerwinkle, Eric;
de Bakker, Paul IW;
Kivimaki, Mika;
Asselbergs, Folkert W;
Sattar, Naveed;
Lawlor, Debbie A;
Whittaker, John;
Davey Smith, George;
Mukamal, Kenneth;
Psaty, Bruce M;
Wilson, James G;
Lange, Leslie A;
Hamidovic, Ajna;
Hingorani, Aroon D;
Nordestgaard, Børge G;
Bobak, Martin;
Leon, David A;
Langenberg, Claudia;
Palmer, Tom M;
Reiner, Alex P;
Keating, Brendan J;
Dudbridge, Frank;
Casas, Juan P;
InterAct Consortium;
(2014)
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.
BMJ (Clinical research ed), 349 (jul10 ).
g4164-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.g4164
Silverwood, Richard J;
Holmes, Michael V;
Dale, Caroline E;
Lawlor, Debbie A;
Whittaker, John C;
Smith, George Davey;
Leon, David A;
Palmer, Tom;
Keating, Brendan J;
Zuccolo, Luisa;
+3 more...
Casas, Juan P;
Dudbridge, Frank;
Alcohol-ADH1B Consortium;
(2014)
Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits.
International journal of epidemiology, 43 (6).
pp. 1781-1790.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyu187
Swerdlow, Daniel I;
Preiss, David;
Kuchenbaecker, Karoline B;
Holmes, Michael V;
Engmann, Jorgen EL;
Shah, Tina;
Sofat, Reecha;
Stender, Stefan;
Johnson, Paul CD;
Scott, Robert A;
+126 more...
Leusink, Maarten;
Verweij, Niek;
Sharp, Stephen J;
Guo, Yiran;
Giambartolomei, Claudia;
Chung, Christina;
Peasey, Anne;
Amuzu, Antoinette;
Li, KaWah;
Palmen, Jutta;
Howard, Philip;
Cooper, Jackie A;
Drenos, Fotios;
Li, Yun R;
Lowe, Gordon;
Gallacher, John;
Stewart, Marlene CW;
Tzoulaki, Ioanna;
Buxbaum, Sarah G;
van der A, Daphne L;
Forouhi, Nita G;
Onland-Moret, N Charlotte;
van der Schouw, Yvonne T;
Schnabel, Renate B;
Hubacek, Jaroslav A;
Kubinova, Ruzena;
Baceviciene, Migle;
Tamosiunas, Abdonas;
Pajak, Andrzej;
Topor-Madry, Roman;
Stepaniak, Urszula;
Malyutina, Sofia;
Baldassarre, Damiano;
Sennblad, Bengt;
Tremoli, Elena;
de Faire, Ulf;
Veglia, Fabrizio;
Ford, Ian;
Jukema, J Wouter;
Westendorp, Rudi GJ;
de Borst, Gert Jan;
de Jong, Pim A;
Algra, Ale;
Spiering, Wilko;
Maitland-van der Zee, Anke H;
Klungel, Olaf H;
de Boer, Anthonius;
Doevendans, Pieter A;
Eaton, Charles B;
Robinson, Jennifer G;
Duggan, David;
DIAGRAM Consortium;
MAGIC Consortium;
InterAct Consortium;
Kjekshus, John;
Downs, John R;
Gotto, Antonio M;
Keech, Anthony C;
Marchioli, Roberto;
Tognoni, Gianni;
Sever, Peter S;
Poulter, Neil R;
Waters, David D;
Pedersen, Terje R;
Amarenco, Pierre;
Nakamura, Haruo;
McMurray, John JV;
Lewsey, James D;
Chasman, Daniel I;
Ridker, Paul M;
Maggioni, Aldo P;
Tavazzi, Luigi;
Ray, Kausik K;
Seshasai, Sreenivasa Rao Kondapally;
Manson, JoAnn E;
Price, Jackie F;
Whincup, Peter H;
Morris, Richard W;
Lawlor, Debbie A;
Smith, George Davey;
Ben-Shlomo, Yoav;
Schreiner, Pamela J;
Fornage, Myriam;
Siscovick, David S;
Cushman, Mary;
Kumari, Meena;
Wareham, Nick J;
Verschuren, WM Monique;
Redline, Susan;
Patel, Sanjay R;
Whittaker, John C;
Hamsten, Anders;
Delaney, Joseph A;
Dale, Caroline;
Gaunt, Tom R;
Wong, Andrew;
Kuh, Diana;
Hardy, Rebecca;
Kathiresan, Sekar;
Castillo, Berta A;
van der Harst, Pim;
Brunner, Eric J;
Tybjaerg-Hansen, Anne;
Marmot, Michael G;
Krauss, Ronald M;
Tsai, Michael;
Coresh, Josef;
Hoogeveen, Ronald C;
Psaty, Bruce M;
Lange, Leslie A;
Hakonarson, Hakon;
Dudbridge, Frank;
Humphries, Steve E;
Talmud, Philippa J;
Kivimäki, Mika;
Timpson, Nicholas J;
Langenberg, Claudia;
Asselbergs, Folkert W;
Voevoda, Mikhail;
Bobak, Martin;
Pikhart, Hynek;
Wilson, James G;
Reiner, Alex P;
Keating, Brendan J;
Hingorani, Aroon D;
Sattar, Naveed;
(2014)
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.
Lancet, 385 (9965).
pp. 351-361.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(14)61183-1
Talmud, Philippa J;
Cooper, Jackie A;
Morris, Richard W;
Dudbridge, Frank;
Shah, Tina;
Engmann, Jorgen;
Dale, Caroline;
White, Jon;
McLachlan, Stela;
Zabaneh, Delilah;
+21 more...
Wong, Andrew;
Ong, Ken K;
Gaunt, Tom;
Holmes, Michael V;
Lawlor, Debbie A;
Richards, Marcus;
Hardy, Rebecca;
Kuh, Diana;
Wareham, Nicholas;
Langenberg, Claudia;
Ben-Shlomo, Yoav;
Wannamethee, S Goya;
Strachan, Mark WJ;
Kumari, Meena;
Whittaker, John C;
Drenos, Fotios;
Kivimaki, Mika;
Hingorani, Aroon D;
Price, Jacqueline F;
Humphries, Steve E;
UCLEB Consortium;
(2014)
Sixty-five common genetic variants and prediction of type 2 diabetes.
Diabetes, 64 (5).
pp. 1830-1840.
ISSN 0012-1797
DOI: https://doi.org/10.2337/db14-1504
Vimaleswaran, Karani S;
Cavadino, Alana;
Berry, Diane J;
LifeLines Cohort Study investigators;
Jorde, Rolf;
Dieffenbach, Aida Karina;
Lu, Chen;
Alves, Alexessander Couto;
Heerspink, Hiddo J Lambers;
Tikkanen, Emmi;
+98 more...
Eriksson, Joel;
Wong, Andrew;
Mangino, Massimo;
Jablonski, Kathleen A;
Nolte, Ilja M;
Houston, Denise K;
Ahluwalia, Tarunveer Singh;
van der Most, Peter J;
Pasko, Dorota;
Zgaga, Lina;
Thiering, Elisabeth;
Vitart, Veronique;
Fraser, Ross M;
Huffman, Jennifer E;
de Boer, Rudolf A;
Schöttker, Ben;
Saum, Kai-Uwe;
McCarthy, Mark I;
Dupuis, Josée;
Herzig, Karl-Heinz;
Sebert, Sylvain;
Pouta, Anneli;
Laitinen, Jaana;
Kleber, Marcus E;
Navis, Gerjan;
Lorentzon, Mattias;
Jameson, Karen;
Arden, Nigel;
Cooper, Jackie A;
Acharya, Jayshree;
Hardy, Rebecca;
Raitakari, Olli;
Ripatti, Samuli;
Billings, Liana K;
Lahti, Jari;
Osmond, Clive;
Penninx, Brenda W;
Rejnmark, Lars;
Lohman, Kurt K;
Paternoster, Lavinia;
Stolk, Ronald P;
Hernandez, Dena G;
Byberg, Liisa;
Hagström, Emil;
Melhus, Håkan;
Ingelsson, Erik;
Mellström, Dan;
Ljunggren, Osten;
Tzoulaki, Ioanna;
McLachlan, Stela;
Theodoratou, Evropi;
Tiesler, Carla MT;
Jula, Antti;
Navarro, Pau;
Wright, Alan F;
Polasek, Ozren;
International Consortium for Blood Pressure (ICBP);
Cohorts for Heart and Aging Research in Genomic Epidemiology (CH;
Global Blood Pressure Genetics (Global BPGen) consortium;
Caroline Hayward;
Wilson, James F;
Rudan, Igor;
Salomaa, Veikko;
Heinrich, Joachim;
Campbell, Harry;
Price, Jacqueline F;
Karlsson, Magnus;
Lind, Lars;
Michaëlsson, Karl;
Bandinelli, Stefania;
Frayling, Timothy M;
Hartman, Catharina A;
Sørensen, Thorkild IA;
Kritchevsky, Stephen B;
Langdahl, Bente Lomholt;
Eriksson, Johan G;
Florez, Jose C;
Spector, Tim D;
Lehtimäki, Terho;
Kuh, Diana;
Humphries, Steve E;
Cooper, Cyrus;
Ohlsson, Claes;
März, Winfried;
de Borst, Martin H;
Kumari, Meena;
Kivimaki, Mika;
Wang, Thomas J;
Power, Chris;
Brenner, Hermann;
Grimnes, Guri;
van der Harst, Pim;
Snieder, Harold;
Hingorani, Aroon D;
Pilz, Stefan;
Whittaker, John C;
Järvelin, Marjo-Riitta;
Hyppönen, Elina;
(2014)
Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study.
The lancet Diabetes & endocrinology, 2 (9).
pp. 719-729.
ISSN 2213-8587
DOI: https://doi.org/10.1016/S2213-8587(14)70113-5
2013
Chan, Kenneth;
Patel, Riyaz S;
Newcombe, Paul;
Nelson, Christopher P;
Qasim, Atif;
Epstein, Stephen E;
Burnett, Susan;
Vaccarino, Viola L;
Zafari, A Maziar;
Shah, Svati H;
+42 more...
Anderson, Jeffrey L;
Carlquist, John F;
Hartiala, Jaana;
Allayee, Hooman;
Hinohara, Kunihiko;
Lee, Bok-Soo;
Erl, Anna;
Ellis, Katrina L;
Goel, Anuj;
Schaefer, Arne S;
El Mokhtari, Nour Eddine;
Goldstein, Benjamin A;
Hlatky, Mark A;
Go, Alan S;
Shen, Gong-Qing;
Gong, Yan;
Pepine, Carl;
Laxton, Ross C;
Whittaker, John C;
Tang, WH Wilson;
Johnson, Julie A;
Wang, Qing K;
Assimes, Themistocles L;
Nöthlings, Ute;
Farrall, Martin;
Watkins, Hugh;
Richards, A Mark;
Cameron, Vicky A;
Muendlein, Axel;
Drexel, Heinz;
Koch, Werner;
Park, Jeong Euy;
Kimura, Akinori;
Shen, Wei-feng;
Simpson, Iain A;
Hazen, Stanley L;
Horne, Benjamin D;
Hauser, Elizabeth R;
Quyyumi, Arshed A;
Reilly, Muredach P;
Samani, Nilesh J;
Ye, Shu;
(2013)
Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis.
Journal of the American College of Cardiology, 61 (9).
pp. 957-970.
ISSN 0735-1097
DOI: https://doi.org/10.1016/j.jacc.2012.10.051
Full text not available from this repository.
Dixon, Peter H;
Wadsworth, Christopher A;
Chambers, Jennifer;
Donnelly, Jennifer;
Cooley, Sharon;
Buckley, Rebecca;
Mannino, Ramona;
Jarvis, Sheba;
Syngelaki, Argyro;
Geenes, Victoria;
+13 more...
Paul, Priyadarshini;
Sothinathan, Meera;
Kubitz, Ralf;
Lammert, Frank;
Tribe, Rachel M;
Ch'ng, Chin Lye;
Marschall, Hanns-Ulrich;
Glantz, Anna;
Khan, Shahid A;
Nicolaides, Kypros;
Whittaker, John;
Geary, Michael;
Williamson, Catherine;
(2013)
A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy.
The American journal of gastroenterology, 109 (1).
pp. 76-84.
ISSN 0002-9270
DOI: https://doi.org/10.1038/ajg.2013.406
Hu, Youna;
Li, Li;
Ehm, Margaret G;
Bing, Nan;
Song, Kijoung;
Nelson, Matthew R;
Talmud, Philippa J;
Hingorani, Aroon D;
Kumari, Meena;
Kivimäki, Mika;
+6 more...
Xu, Chun-Fang;
Waterworth, Dawn M;
Whittaker, John C;
Abecasis, Gonçalo R;
Spino, Cathie;
Kang, Hyun Min;
(2013)
The benefits of using genetic information to design prevention trials.
American journal of human genetics, 92 (4).
pp. 547-557.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2013.03.003
Full text not available from this repository.
Khan, Tauseef A;
Shah, Tina;
Prieto, David;
Zhang, Weili;
Price, Jackie;
Fowkes, Gerald R;
Cooper, Jackie;
Talmud, Philippa J;
Humphries, Steve E;
Sundstrom, Johan;
+39 more...
Hubacek, Jaroslav A;
Ebrahim, Shah;
Lawlor, Debbie A;
Ben-Shlomo, Yoav;
Abdollahi, Mohammad R;
Slooter, Arjen JC;
Szolnoki, Zoltan;
Sandhu, Manjinder;
Wareham, Nicholas;
Frikke-Schmidt, Ruth;
Tybjærg-Hansen, Anne;
Fillenbaum, Gerda;
Heijmans, Bastiaan T;
Katsuya, Tomohiro;
Gromadzka, Grazyna;
Singleton, Andrew;
Ferrucci, Luigi;
Hardy, John;
Worrall, Bradford;
Rich, Stephen S;
Matarin, Mar;
Whittaker, John;
Gaunt, Tom R;
Whincup, Peter;
Morris, Richard;
Deanfield, John;
Donald, Ann;
Davey Smith, George;
Kivimaki, Mika;
Kumari, Meena;
Smeeth, Liam;
Khaw, Kay-Tee;
Nalls, Michael;
Meschia, James;
Sun, Kai;
Hui, Rutai;
Day, Ian;
Hingorani, Aroon D;
Casas, Juan P;
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Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.
International journal of epidemiology, 42 (2).
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ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyt034
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Mann, Andrea G;
Mangtani, Punam;
Russell, Colin A;
Whittaker, John C;
(2013)
The impact of targeting all elderly persons in England and Wales for yearly influenza vaccination: excess mortality due to pneumonia or influenza and time trend study.
BMJ open, 3 (8).
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ISSN 2044-6055
DOI: https://doi.org/10.1136/bmjopen-2013-002743
Shah, Sonia;
Casas, Juan-Pablo;
Drenos, Fotios;
Whittaker, John;
Deanfield, John;
Swerdlow, Daniel I;
Holmes, Michael V;
Kivimaki, Mika;
Langenberg, Claudia;
Wareham, Nick;
+13 more...
Gertow, Karl;
Sennblad, Bengt;
Strawbridge, Rona J;
Baldassarre, Damiano;
Veglia, Fabrizio;
Tremoli, Elena;
Gigante, Bruna;
de Faire, Ulf;
Kumari, Meena;
Talmud, Philippa J;
Hamsten, Anders;
Humphries, Steve E;
Hingorani, Aroon D;
(2013)
Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.
Circulation Cardiovascular genetics, 6 (1).
pp. 63-72.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.112.963140
Full text not available from this repository.
Shah, Tina;
Engmann, Jorgen;
Dale, Caroline;
Shah, Sonia;
White, Jon;
Giambartolomei, Claudia;
McLachlan, Stela;
Zabaneh, Delilah;
Cavadino, Alana;
Finan, Chris;
+37 more...
Wong, Andrew;
Amuzu, Antoinette;
Ong, Ken;
Gaunt, Tom;
Holmes, Michael V;
Warren, Helen;
Swerdlow, Daniel I;
Davies, Teri-Louise;
Drenos, Fotios;
Cooper, Jackie;
Sofat, Reecha;
Caulfield, Mark;
Ebrahim, Shah;
Lawlor, Debbie A;
Talmud, Philippa J;
Humphries, Steve E;
Power, Christine;
Hypponen, Elina;
Richards, Marcus;
Hardy, Rebecca;
Kuh, Diana;
Wareham, Nicholas;
Langenberg, Claudia;
Ben-Shlomo, Yoav;
Day, Ian N;
Whincup, Peter;
Morris, Richard;
Strachan, Mark WJ;
Price, Jacqueline;
Kumari, Meena;
Kivimaki, Mika;
Plagnol, Vincent;
Dudbridge, Frank;
Whittaker, John C;
Casas, Juan P;
Hingorani, Aroon D;
UCLEB Consortium;
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Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
PloS one, 8 (8).
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ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0071345
Shah, Tina;
Zabaneh, Delilah;
Gaunt, Tom;
Swerdlow, Daniel I;
Shah, Sonia;
Talmud, Philippa J;
Day, Ian N;
Whittaker, John;
Holmes, Michael V;
Sofat, Reecha;
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Humphries, Steve E;
Kivimaki, Mika;
Kumari, Meena;
Hingorani, Aroon D;
Casas, Juan P;
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Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.
Circulation Cardiovascular genetics, 6 (2).
pp. 163-170.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.112.964254
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Talmud, Philippa J;
Shah, Sonia;
Whittall, Ros;
Futema, Marta;
Howard, Philip;
Cooper, Jackie A;
Harrison, Seamus C;
Li, Kawah;
Drenos, Fotios;
Karpe, Frederik;
+9 more...
Neil, H Andrew W;
Descamps, Olivier S;
Langenberg, Claudia;
Lench, Nicholas;
Kivimaki, Mika;
Whittaker, John;
Hingorani, Aroon D;
Kumari, Meena;
Humphries, Steve E;
(2013)
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
Lancet, 381 (9874).
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ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(12)62127-8
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Vimaleswaran, KS;
Cavadino, A;
Berry, DJ;
Whittaker, JC;
Power, C;
Järvelin, M-R;
Hyppönen, E;
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Genetic association analysis of vitamin D pathway with obesity traits.
International journal of obesity and related metabolic disorders, 37 (10).
pp. 1399-1406.
ISSN 0307-0565
DOI: https://doi.org/10.1038/ijo.2013.6
Full text not available from this repository.
Vimaleswaran, Karani S;
Berry, Diane J;
Lu, Chen;
Tikkanen, Emmi;
Pilz, Stefan;
Hiraki, Linda T;
Cooper, Jason D;
Dastani, Zari;
Li, Rui;
Houston, Denise K;
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Wood, Andrew R;
Michaëlsson, Karl;
Vandenput, Liesbeth;
Zgaga, Lina;
Yerges-Armstrong, Laura M;
McCarthy, Mark I;
Dupuis, Josée;
Kaakinen, Marika;
Kleber, Marcus E;
Jameson, Karen;
Arden, Nigel;
Raitakari, Olli;
Viikari, Jorma;
Lohman, Kurt K;
Ferrucci, Luigi;
Melhus, Håkan;
Ingelsson, Erik;
Byberg, Liisa;
Lind, Lars;
Lorentzon, Mattias;
Salomaa, Veikko;
Campbell, Harry;
Dunlop, Malcolm;
Mitchell, Braxton D;
Herzig, Karl-Heinz;
Pouta, Anneli;
Hartikainen, Anna-Liisa;
Genetic Investigation of Anthropometric Traits-GIANT Consortium;
Streeten, Elizabeth A;
Theodoratou, Evropi;
Jula, Antti;
Wareham, Nicholas J;
Ohlsson, Claes;
Frayling, Timothy M;
Kritchevsky, Stephen B;
Spector, Timothy D;
Richards, J Brent;
Lehtimäki, Terho;
Ouwehand, Willem H;
Kraft, Peter;
Cooper, Cyrus;
März, Winfried;
Power, Chris;
Loos, Ruth JF;
Wang, Thomas J;
Järvelin, Marjo-Riitta;
Whittaker, John C;
Hingorani, Aroon D;
Hyppönen, Elina;
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Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.
PLoS medicine, 10 (2).
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Warren, Helen;
Casas, Juan-Pablo;
Hingorani, Aroon;
Dudbridge, Frank;
Whittaker, John;
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Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores.
Genetic epidemiology, 38 (1).
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ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.21777
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Asselbergs, Folkert W;
Guo, Yiran;
van Iperen, Erik PA;
Sivapalaratnam, Suthesh;
Tragante, Vinicius;
Lanktree, Matthew B;
Lange, Leslie A;
Almoguera, Berta;
Appelman, Yolande E;
Barnard, John;
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Baumert, Jens;
Beitelshees, Amber L;
Bhangale, Tushar R;
Chen, Yii-Der Ida;
Gaunt, Tom R;
Gong, Yan;
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Kleber, Marcus E;
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Li, Mingyao;
Li, Yun R;
Liu, Kiang;
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Meijs, Matthijs FL;
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Musunuru, Kiran;
Nelson, Christopher P;
O'Connell, Jeffery R;
Padmanabhan, Sandosh;
Pankow, James S;
Pankratz, Nathan;
Rafelt, Suzanne;
Rajagopalan, Ramakrishnan;
Romaine, Simon PR;
Schork, Nicholas J;
Shaffer, Jonathan;
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Smith, Erin N;
Tischfield, Sam E;
van der Most, Peter J;
van Vliet-Ostaptchouk, Jana V;
Verweij, Niek;
Volcik, Kelly A;
Zhang, Li;
Bailey, Kent R;
Bailey, Kristian M;
Bauer, Florianne;
Boer, Jolanda MA;
Braund, Peter S;
Burt, Amber;
Burton, Paul R;
Buxbaum, Sarah G;
Chen, Wei;
Cooper-Dehoff, Rhonda M;
Cupples, L Adrienne;
deJong, Jonas S;
Delles, Christian;
Duggan, David;
Fornage, Myriam;
Furlong, Clement E;
Glazer, Nicole;
Gums, John G;
Hastie, Claire;
Holmes, Michael V;
Illig, Thomas;
Kirkland, Susan A;
Kivimaki, Mika;
Klein, Ronald;
Klein, Barbara E;
Kooperberg, Charles;
Kottke-Marchant, Kandice;
Kumari, Meena;
LaCroix, Andrea Z;
Mallela, Laya;
Murugesan, Gurunathan;
Ordovas, Jose;
Ouwehand, Willem H;
Post, Wendy S;
Saxena, Richa;
Scharnagl, Hubert;
Schreiner, Pamela J;
Shah, Tina;
Shields, Denis C;
Shimbo, Daichi;
Srinivasan, Sathanur R;
Stolk, Ronald P;
Swerdlow, Daniel I;
Taylor, Herman A;
Topol, Eric J;
Toskala, Elina;
van Pelt, Joost L;
van Setten, Jessica;
Yusuf, Salim;
Whittaker, John C;
Zwinderman, AH;
LifeLines Cohort Study;
Anand, Sonia S;
Balmforth, Anthony J;
Berenson, Gerald S;
Bezzina, Connie R;
Boehm, Bernhard O;
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Clarke, Robert;
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Doevendans, Pieter A;
Dominiczak, Anna F;
Hall, Alistair S;
Hartman, Catharina A;
Hengstenberg, Christian;
Hillege, Hans L;
Hofker, Marten H;
Humphries, Steve E;
Jarvik, Gail P;
Johnson, Julie A;
Kaess, Bernhard M;
Kathiresan, Sekar;
Koenig, Wolfgang;
Lawlor, Debbie A;
März, Winfried;
Melander, Olle;
Mitchell, Braxton D;
Montgomery, Grant W;
Munroe, Patricia B;
Murray, Sarah S;
Newhouse, Stephen J;
Onland-Moret, N Charlotte;
Poulter, Neil;
Psaty, Bruce;
Redline, Susan;
Rich, Stephen S;
Rotter, Jerome I;
Schunkert, Heribert;
Sever, Peter;
Shuldiner, Alan R;
Silverstein, Roy L;
Stanton, Alice;
Thorand, Barbara;
Trip, Mieke D;
Tsai, Michael Y;
van der Harst, Pim;
van der Schoot, Ellen;
van der Schouw, Yvonne T;
Verschuren, WM Monique;
Watkins, Hugh;
Wilde, Arthur AM;
Wolffenbuttel, Bruce HR;
Whitfield, John B;
Hovingh, G Kees;
Ballantyne, Christie M;
Wijmenga, Cisca;
Reilly, Muredach P;
Martin, Nicholas G;
Wilson, James G;
Rader, Daniel J;
Samani, Nilesh J;
Reiner, Alex P;
Hegele, Robert A;
Kastelein, John JP;
Hingorani, Aroon D;
Talmud, Philippa J;
Hakonarson, Hakon;
Elbers, Clara C;
Keating, Brendan J;
Drenos, Fotios;
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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
American journal of human genetics, 91 (5).
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DOI: https://doi.org/10.1016/j.ajhg.2012.08.032
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Bacanu, S-A;
Whittaker, JC;
Nelson, MR;
(2012)
How informative is a negative finding in a small pharmacogenetic study?
The pharmacogenomics journal, 12 (2).
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ISSN 1470-269X
DOI: https://doi.org/10.1038/tpj.2011.58
Bacanu, Silviu-Alin;
Nelson, Matthew R;
Whittaker, John C;
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Comparison of statistical tests for association between rare variants and binary traits.
PloS one, 7 (8).
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DOI: https://doi.org/10.1371/journal.pone.0042530
Gaunt, Tom R;
Shah, Sonia;
Nelson, Christopher P;
Drenos, Fotios;
Braund, Peter S;
Adeniran, Ismail;
Folkersen, Lasse;
Lawlor, Debbie A;
Casas, Juan-Pablo;
Amuzu, Antoinette;
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Kivimaki, Mika;
Whittaker, John;
Eriksson, Per;
Zhang, Henggui;
Hancox, Jules C;
Tomaszewski, Maciej;
Burton, Paul R;
Tobin, Martin D;
Humphries, Steve E;
Talmud, Philippa J;
Macfarlane, Peter W;
Hingorani, Aroon D;
Samani, Nilesh J;
Kumari, Meena;
Day, Ian NM;
(2012)
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
Circulation Cardiovascular genetics, 5 (6).
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ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.112.962852
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Ishida, Miho;
Monk, David;
Duncan, Andrew J;
Abu-Amero, Sayeda;
Chong, Jiehan;
Ring, Susan M;
Pembrey, Marcus E;
Hindmarsh, Peter C;
Whittaker, John C;
Stanier, Philip;
+1 more...
Moore, Gudrun E;
(2012)
Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight.
American journal of human genetics, 90 (4).
pp. 715-719.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2012.02.021
Full text not available from this repository.
McCarthy, Linda C;
Newcombe, Paul J;
Whittaker, John C;
Wurzelmann, John I;
Fries, Michael A;
Burnham, Nancy R;
Cai, Gengqian;
Stinnett, Sandra W;
Trivedi, Trupti M;
Xu, Chun-Fang;
(2012)
Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design.
American journal of ophthalmology, 154 (3).
568-578.e12.
ISSN 0002-9394
DOI: https://doi.org/10.1016/j.ajo.2012.03.021
Full text not available from this repository.
Mead, Simon;
Uphill, James;
Beck, John;
Poulter, Mark;
Campbell, Tracy;
Lowe, Jessica;
Adamson, Gary;
Hummerich, Holger;
Klopp, Norman;
Rückert, Ina-Maria;
+11 more...
Wichmann, H-Erich;
Azazi, Dhoyazan;
Plagnol, Vincent;
Pako, Wandagi H;
Whitfield, Jerome;
Alpers, Michael P;
Whittaker, John;
Balding, David J;
Zerr, Inga;
Kretzschmar, Hans;
Collinge, John;
(2012)
Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP.
Human molecular genetics, 21 (8).
pp. 1897-1906.
ISSN 0964-6906
DOI: https://doi.org/10.1093/hmg/ddr607
Full text not available from this repository.
Nelson, Matthew R;
Wegmann, Daniel;
Ehm, Margaret G;
Kessner, Darren;
St Jean, Pamela;
Verzilli, Claudio;
Shen, Judong;
Tang, Zhengzheng;
Bacanu, Silviu-Alin;
Fraser, Dana;
+21 more...
Warren, Liling;
Aponte, Jennifer;
Zawistowski, Matthew;
Liu, Xiao;
Zhang, Hao;
Zhang, Yong;
Li, Jun;
Li, Yun;
Li, Li;
Woollard, Peter;
Topp, Simon;
Hall, Matthew D;
Nangle, Keith;
Wang, Jun;
Abecasis, Gonçalo;
Cardon, Lon R;
Zöllner, Sebastian;
Whittaker, John C;
Chissoe, Stephanie L;
Novembre, John;
Mooser, Vincent;
(2012)
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people.
Science (New York, NY), 337 (6090).
pp. 100-104.
ISSN 0036-8075
DOI: https://doi.org/10.1126/science.1217876
Full text not available from this repository.
Newcombe, Paul J;
Reck, Brian H;
Sun, Jielin;
Platek, Greg T;
Verzilli, Claudio;
Kader, A Karim;
Kim, Seong-Tae;
Hsu, Fang-Chi;
Zhang, Zheng;
Zheng, S Lilly;
+6 more...
Mooser, Vincent E;
Condreay, Lynn D;
Spraggs, Colin F;
Whittaker, John C;
Rittmaster, Roger S;
Xu, Jianfeng;
(2012)
A comparison of Bayesian and frequentist approaches to incorporating external information for the prediction of prostate cancer risk.
Genetic epidemiology, 36 (1).
pp. 71-83.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.21600
Full text not available from this repository.
Rubio, Justin P;
Topp, Simon;
Warren, Liling;
St Jean, Pamela L;
Wegmann, Daniel;
Kessner, Darren;
Novembre, John;
Shen, Judong;
Fraser, Dana;
Aponte, Jennifer;
+7 more...
Nangle, Keith;
Cardon, Lon R;
Ehm, Margaret G;
Chissoe, Stephanie L;
Whittaker, John C;
Nelson, Matthew R;
Mooser, Vincent E;
(2012)
Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe.
Human mutation, 33 (7).
pp. 1087-1098.
ISSN 1059-7794
DOI: https://doi.org/10.1002/humu.22075
Full text not available from this repository.
Shah, Sonia;
Casas, Juan P;
Gaunt, Tom R;
Cooper, Jackie;
Drenos, Fotios;
Zabaneh, Delilah;
Swerdlow, Daniel I;
Shah, Tina;
Sofat, Reecha;
Palmen, Jutta;
+10 more...
Kumari, Meena;
Kivimaki, Mika;
Ebrahim, Shah;
Smith, George Davey;
Lawlor, Debbie A;
Talmud, Philippa J;
Whittaker, John;
Day, Ian NM;
Hingorani, Aroon D;
Humphries, Steve E;
(2012)
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
European heart journal, 34 (13).
pp. 972-981.
ISSN 0195-668X
DOI: https://doi.org/10.1093/eurheartj/ehs243
Full text not available from this repository.
Sofat, Reecha;
Casas, Juan P;
Webster, Andrew R;
Bird, Alan C;
Mann, Samantha S;
Yates, John RW;
Moore, Anthony T;
Sepp, Tiina;
Cipriani, Valentina;
Bunce, Catey;
+43 more...
Khan, Jane C;
Shahid, Humma;
Swaroop, Anand;
Abecasis, Gonçalo;
Branham, Kari EH;
Zareparsi, Sepideh;
Bergen, Arthur A;
Klaver, Caroline CW;
Baas, Dominique C;
Zhang, Kang;
Chen, Yuhong;
Gibbs, Daniel;
Weber, Bernhard HF;
Keilhauer, Claudia N;
Fritsche, Lars G;
Lotery, Andrew;
Cree, Angela J;
Griffiths, Helen L;
Bhattacharya, Shomi S;
Chen, Li L;
Jenkins, Sharon A;
Peto, Tunde;
Lathrop, Mark;
Leveillard, Thierry;
Gorin, Michael B;
Weeks, Daniel E;
Ortube, Maria Carolina;
Ferrell, Robert E;
Jakobsdottir, Johanna;
Conley, Yvette P;
Rahu, Mati;
Seland, Johan H;
Soubrane, Gisele;
Topouzis, Fotis;
Vioque, Jesus;
Tomazzoli, Laura;
Young, Ian;
Whittaker, John;
Chakravarthy, Usha;
de Jong, Paulus TVM;
Smeeth, Liam;
Fletcher, Astrid;
Hingorani, Aroon D;
(2012)
Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype.
International journal of epidemiology, 41 (1).
pp. 250-262.
ISSN 0300-5771
DOI: https://doi.org/10.1093/ije/dyr204
Full text not available from this repository.
Song, K;
Nelson, MR;
Aponte, J;
Manas, ES;
Bacanu, S-A;
Yuan, X;
Kong, X;
Cardon, L;
Mooser, VE;
Whittaker, JC;
+1 more...
Waterworth, DM;
(2012)
Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations.
The pharmacogenomics journal, 12 (5).
pp. 425-431.
ISSN 1470-269X
DOI: https://doi.org/10.1038/tpj.2011.20
Warren, Liling L;
Li, Li;
Nelson, Matthew R;
Ehm, Margaret G;
Shen, Judong;
Fraser, Dana J;
Aponte, Jennifer L;
Nangle, Keith L;
Slater, Andrew J;
Woollard, Peter M;
+12 more...
Hall, Matt D;
Topp, Simon D;
Yuan, Xin;
Cardon, Lon R;
Chissoe, Stephanie L;
Mooser, Vincent;
Morris, Andrew D;
Palmer, Colin NA;
Perry, John R;
Frayling, Timothy M;
Whittaker, John C;
Waterworth, Dawn M;
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Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation.
Diabetes, 61 (5).
pp. 1297-1301.
ISSN 0012-1797
DOI: https://doi.org/10.2337/db11-0985
2011
Angelakopoulou, Aspasia;
Shah, Tina;
Sofat, Reecha;
Shah, Sonia;
Berry, Diane J;
Cooper, Jackie;
Palmen, Jutta;
Tzoulaki, Ioanna;
Wong, Andrew;
Jefferis, Barbara J;
+35 more...
Maniatis, Nikolas;
Drenos, Fotios;
Gigante, Bruna;
Hardy, Rebecca;
Laxton, Ross C;
Leander, Karin;
Motterle, Anna;
Simpson, Iain A;
Smeeth, Liam;
Thomson, Andy;
Verzilli, Claudio;
Kuh, Diana;
Ireland, Helen;
Deanfield, John;
Caulfield, Mark;
Wallace, Chris;
Samani, Nilesh;
Munroe, Patricia B;
Lathrop, Mark;
Fowkes, F Gerry R;
Marmot, Michael;
Whincup, Peter H;
Whittaker, John C;
de Faire, Ulf;
Kivimaki, Mika;
Kumari, Meena;
Hypponen, Elina;
Power, Chris;
Humphries, Steve E;
Talmud, Philippa J;
Price, Jackie;
Morris, Richard W;
Ye, Shu;
Casas, Juan P;
Hingorani, Aroon D;
(2011)
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
European heart journal, 33 (3).
pp. 393-407.
ISSN 0195-668X
DOI: https://doi.org/10.1093/eurheartj/ehr225
Bacanu, Silviu-Alin;
Nelson, Matthew R;
Whittaker, John C;
(2011)
Comparison of methods and sampling designs to test for association between rare variants and quantitative traits.
Genetic epidemiology, 35 (4).
pp. 226-235.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20570
Full text not available from this repository.
Balchin, Imelda;
Whittaker, John C;
Lamont, Ronald F;
Steer, Philip J;
(2011)
Maternal and fetal characteristics associated with meconium-stained amniotic fluid.
Obstetrics and gynecology, 117 (4).
pp. 828-835.
ISSN 0029-7844
DOI: https://doi.org/10.1097/AOG.0b013e3182117a26
Full text not available from this repository.
Brown, Andrew Anand;
Richardson, Sylvia;
Whittaker, John;
(2011)
Application of the Lasso to Expression Quantitative Trait Loci Mapping.
Statistical applications in genetics and molecular biology, 10 (1).
ISSN 2194-6302
DOI: https://doi.org/10.2202/1544-6115.1606
Full text not available from this repository.
C Reactive Protein Coronary Heart Disease Genetics Collaboration;
Wensley, Frances;
Gao, Pei;
Burgess, Stephen;
Kaptoge, Stephen;
Di Angelantonio, Emanuele;
Shah, Tina;
Engert, James C;
Clarke, Robert;
Davey-Smith, George;
+12 more...
Nordestgaard, Børge G;
Saleheen, Danish;
Samani, Nilesh J;
Sandhu, Manjinder;
Anand, Sonia;
Pepys, Mark B;
Smeeth, Liam;
Whittaker, John;
Casas, Juan Pablo;
Thompson, Simon G;
Hingorani, Aroon D;
Danesh, John;
(2011)
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data.
BMJ, 342 (feb15 ).
d548-.
ISSN 1468-5833
DOI: https://doi.org/10.1136/bmj.d548
De Iorio, Maria;
Newcombe, Paul J;
Tachmazidou, Ioanna;
Verzilli, Claudio J;
Whittaker, John C;
(2011)
Bayesian semiparametric meta-analysis for genetic association studies.
Genetic epidemiology, 35 (5).
pp. 333-340.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20581
Full text not available from this repository.
Dixon, PH;
Wadsworth, CA;
Chambers, J;
Donnelly, JC;
Cooley, SM;
Kubitz, R;
Lammert, F;
Marschall, HU;
Glantz, A;
Khan, SA;
+3 more...
Whittaker, J;
Geary, M;
Williamson, C;
(2011)
DOES COMMON GENETIC VARIATION AROUND THE PREGNANE-X RECEPTOR INFLUENCE SUSCEPTIBILITY TO INTRAHEPATIC CHOLESTASIS OF PREGNANCY?
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/18504
Full text not available from this repository.
Holmes, Michael V;
Newcombe, Paul;
Hubacek, Jaroslav A;
Sofat, Reecha;
Ricketts, Sally L;
Cooper, Jackie;
Breteler, Monique MB;
Bautista, Leonelo E;
Sharma, Pankaj;
Whittaker, John C;
+36 more...
Smeeth, Liam;
Fowkes, F Gerald R;
Algra, Ale;
Shmeleva, Veronika;
Szolnoki, Zoltan;
Roest, Mark;
Linnebank, Michael;
Zacho, Jeppe;
Nalls, Michael A;
Singleton, Andrew B;
Ferrucci, Luigi;
Hardy, John;
Worrall, Bradford B;
Rich, Stephen S;
Matarin, Mar;
Norman, Paul E;
Flicker, Leon;
Almeida, Osvaldo P;
van Bockxmeer, Frank M;
Shimokata, Hiroshi;
Khaw, Kay-Tee;
Wareham, Nicholas J;
Bobak, Martin;
Sterne, Jonathan AC;
Smith, George Davey;
Talmud, Philippa J;
van Duijn, Cornelia;
Humphries, Steve E;
Price, Jackie F;
Ebrahim, Shah;
Lawlor, Debbie A;
Hankey, Graeme J;
Meschia, James F;
Sandhu, Manjinder S;
Hingorani, Aroon D;
Casas, Juan P;
(2011)
Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials.
Lancet, 378 (9791).
pp. 584-594.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(11)60872-6
Hyppönen, Elina;
Fararouei, Mohammad;
Sovio, Ulla;
Hartikainen, Anna-Liisa;
Pouta, Anneli;
Robertson, Claire;
Whittaker, John C;
Jarvelin, Marjo-Riitta;
(2011)
High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort.
The Journal of nutrition, 141 (5).
pp. 843-848.
ISSN 0022-3166
DOI: https://doi.org/10.3945/jn.110.133009
Full text not available from this repository.
Li, Li;
Li, Yun;
Browning, Sharon R;
Browning, Brian L;
Slater, Andrew J;
Kong, Xiangyang;
Aponte, Jennifer L;
Mooser, Vincent E;
Chissoe, Stephanie L;
Whittaker, John C;
+2 more...
Nelson, Matthew R;
Ehm, Margaret Gelder;
(2011)
Performance of genotype imputation for rare variants identified in exons and flanking regions of genes.
PloS one, 6 (9).
e24945-.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0024945
Shah, Sonia;
Nelson, Christopher P;
Gaunt, Tom R;
van der Harst, Pim;
Barnes, Timothy;
Braund, Peter S;
Lawlor, Debbie A;
Casas, Juan-Pablo;
Padmanabhan, Sandosh;
Drenos, Fotios;
+30 more...
Kivimaki, Mika;
Talmud, Philippa J;
Humphries, Steve E;
Whittaker, John;
Morris, Richard W;
Whincup, Peter H;
Dominiczak, Anna;
Munroe, Patricia B;
Johnson, Toby;
Goodall, Alison H;
Cambien, Francois;
Diemert, Patrick;
Hengstenberg, Christian;
Ouwehand, Willem H;
Felix, Janine F;
Glazer, Nicole L;
Tomaszewski, Maciej;
Burton, Paul R;
Tobin, Martin D;
van Veldhuisen, Dirk J;
de Boer, Rudolf A;
Navis, Gerjan;
van Gilst, Wiek H;
Mayosi, Bongani M;
Thompson, John R;
Kumari, Meena;
MacFarlane, Peter W;
Day, Ian NM;
Hingorani, Aroon D;
Samani, Nilesh J;
(2011)
Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.
Circulation Cardiovascular genetics, 4 (6).
pp. 626-635.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.111.960203
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Spraggs, Colin F;
Budde, Laura R;
Briley, Linda P;
Bing, Nan;
Cox, Charles J;
King, Karen S;
Whittaker, John C;
Mooser, Vincent E;
Preston, Alaknanda J;
Stein, Steven H;
+1 more...
Cardon, Lon R;
(2011)
HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer.
Journal of clinical oncology, 29 (6).
pp. 667-673.
ISSN 0732-183X
DOI: https://doi.org/10.1200/JCO.2010.31.3197
Full text not available from this repository.
Talmud, PJ;
Cooper, JA;
Gaunt, T;
Holmes, MV;
Shah, S;
Palmen, J;
Drenos, F;
Shah, T;
Kumari, M;
Kivimaki, M;
+6 more...
Whittaker, J;
Lawlor, DA;
Day, IN;
Hingorani, AD;
Casas, JP;
Humphries, SE;
(2011)
Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies.
Diabetologia, 54 (7).
pp. 1710-1719.
ISSN 0012-186X
DOI: https://doi.org/10.1007/s00125-011-2108-6
Wadsworth, Christopher A;
Dixon, Peter H;
Wong, Jason H;
Chapman, Michael H;
McKay, Siobhan C;
Sharif, Amar;
Spalding, Duncan R;
Pereira, Stephen P;
Thomas, Howard C;
Taylor-Robinson, Simon D;
+3 more...
Whittaker, John;
Williamson, Catherine;
Khan, Shahid A;
(2011)
Genetic factors in the pathogenesis of cholangiocarcinoma.
Digestive diseases (Basel, Switzerland), 29 (1).
pp. 93-97.
ISSN 0257-2753
DOI: https://doi.org/10.1159/000324688
Full text not available from this repository.
Xu, Chun-Fang;
Bing, Nan X;
Ball, Howard A;
Rajagopalan, Dilip;
Sternberg, Cora N;
Hutson, Thomas E;
de Souza, Paul;
Xue, Zhengyu G;
McCann, Lauren;
King, Karen S;
+6 more...
Ragone, Leigh J;
Whittaker, John C;
Spraggs, Colin F;
Cardon, Lon R;
Mooser, Vincent E;
Pandite, Lini N;
(2011)
Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes.
Journal of clinical oncology, 29 (18).
pp. 2557-2564.
ISSN 0732-183X
DOI: https://doi.org/10.1200/JCO.2010.32.9110
Full text not available from this repository.
Zabaneh, Delilah;
Gaunt, Tom R;
Kumari, Meena;
Drenos, Fotios;
Shah, Sonia;
Berry, Diane;
Power, Chris;
Hypponen, Elina;
Shah, Tina;
Palmen, Jutta;
+18 more...
Pallas, Jacky;
Talmud, Philippa J;
Casas, Juan Pablo;
Sofat, Reecha;
Lowe, Gordon;
Rumley, Ann;
Morris, Richard W;
Whincup, Peter H;
Rodriguez, Santiago;
Ebrahim, Shah;
Marmot, Michael G;
Smith, George Davey;
Lawlor, Debbie A;
Kivimaki, Mika;
Whittaker, John;
Hingorani, Aroon D;
Day, Ian N;
Humphries, Steve E;
(2011)
Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.
Annals of human genetics, 75 (4).
pp. 456-467.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2011.00654.x
Full text not available from this repository.
Zabaneh, Delilah;
Kumari, Meena;
Sandhu, Manj;
Wareham, Nick;
Wainwright, Nick;
Papamarkou, Theodore;
Hopewell, Jemma;
Clarke, Robert;
Li, KaWah;
Palmen, Jutta;
+16 more...
Talmud, Philippa J;
Kronenberg, Florian;
Lamina, Claudia;
Summerer, Monika;
Paulweber, Bernhard;
Price, Jackie;
Fowkes, Gerry;
Stewart, Marlene;
Drenos, Fotios;
Shah, Sonia;
Shah, Tina;
Casas, Juan-Pablo;
Kivimaki, Mika;
Whittaker, John;
Hingorani, Aroon D;
Humphries, Steve E;
(2011)
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
Atherosclerosis, 217 (2).
pp. 447-451.
ISSN 0021-9150
DOI: https://doi.org/10.1016/j.atherosclerosis.2011.04.015
Full text not available from this repository.
2010
Burgess, Stephen;
Thompson, Simon G;
CRP CHD Genetics Collaboration;
Burgess, S;
Thompson, SG;
Andrews, G;
Samani, NJ;
Hall, A;
Whincup, P;
Morris, R;
+107 more...
Lawlor, DA;
Davey Smith, G;
Timpson, N;
Ebrahim, S;
Ben-Shlomo, Y;
Davey Smith, G;
Timpson, N;
Brown, M;
Ricketts, S;
Sandhu, M;
Reiner, A;
Psaty, B;
Lange, L;
Cushman, M;
Hung, J;
Thompson, P;
Beilby, J;
Warrington, N;
Palmer, LJ;
Nordestgaard, BG;
Tybjaerg-Hansen, A;
Zacho, J;
Wu, C;
Lowe, G;
Tzoulaki, I;
Kumari, M;
Sandhu, M;
Yamamoto, JF;
Chiodini, B;
Franzosi, M;
Hankey, GJ;
Jamrozik, K;
Palmer, L;
Rimm, E;
Pai, J;
Psaty, B;
Heckbert, S;
Bis, J;
Anand, S;
Engert, J;
Collins, R;
Clarke, R;
Melander, O;
Berglund, G;
Ladenvall, P;
Johansson, L;
Jansson, J-H;
Hallmans, G;
Hingorani, A;
Humphries, S;
Rimm, E;
Manson, J;
Pai, J;
Watkins, H;
Clarke, R;
Hopewell, J;
Saleheen, D;
Frossard, R;
Danesh, J;
Sattar, N;
Robertson, M;
Shepherd, J;
Schaefer, E;
Hofman, A;
Witteman, JCM;
Kardys, I;
Ben-Shlomo, Y;
Davey Smith, G;
Timpson, N;
de Faire, U;
Bennet, A;
Sattar, N;
Ford, I;
Packard, C;
Kumari, M;
Manson, J;
Lawlor, Debbie A;
Davey Smith, George;
Anand, S;
Collins, R;
Casas, JP;
Danesh, J;
Davey Smith, G;
Franzosi, M;
Hingorani, A;
Lawlor, DA;
Manson, J;
Nordestgaard, BG;
Samani, NJ;
Sandhu, M;
Smeeth, L;
Wensley, F;
Anand, S;
Bowden, J;
Burgess, S;
Casas, JP;
Di Angelantonio, E;
Engert, J;
Gao, P;
Shah, T;
Smeeth, L;
Thompson, SG;
Verzilli, C;
Walker, M;
Whittaker, J;
Hingorani, A;
Danesh, J;
(2010)
Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables.
Statistics in medicine, 29 (12).
pp. 1298-1311.
ISSN 0277-6715
DOI: https://doi.org/10.1002/sim.3843
Full text not available from this repository.
Dixon, PH;
Wadsworth, CA;
Chambers, J;
Donnelly, J;
Cooley, SM;
Jarvis, S;
Kubitz, R;
Lammert, F;
Marschall, HU;
Glantz, A;
+4 more...
Khan, SA;
Whittaker, J;
Geary, M;
Williamson, C;
(2010)
The Role of Common Genetic Variation around Six Candidate Loci for Susceptibility to Intrahepatic Cholestasis of Pregnancy.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/902
Full text not available from this repository.
Fararouei, Mohammad;
Robertson, Claire;
Whittaker, John;
Sovio, Ulla;
Ruokonen, Aimo;
Pouta, Anneli;
Hartikainen, Anna-Liisa;
Jarvelin, Marjo-Riitta;
Hyppönen, Elina;
(2010)
Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years.
The British journal of nutrition, 104 (9).
pp. 1363-1368.
ISSN 0007-1145
DOI: https://doi.org/10.1017/S0007114510002175
Morris, David L;
Roberts, Amy L;
Witherden, Abigail S;
Tarzi, Ruth;
Barros, Paula;
Whittaker, John C;
Cook, Terence H;
Aitman, Timothy J;
Vyse, Timothy J;
(2010)
Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus.
European journal of human genetics, 18 (9).
pp. 1027-1031.
ISSN 1018-4813
DOI: https://doi.org/10.1038/ejhg.2010.56
Full text not available from this repository.
Nonyane, BAS;
Whittaker, JC;
(2010)
A variance components factor model for genetic association studies: a Bayesian analysis.
Genetic epidemiology, 34 (6).
pp. 529-536.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20503
Full text not available from this repository.
Shah, S;
Drenos, F;
Shah, T;
Palmen, J;
Sofat, R;
Kumari, M;
Pallas, J;
MacFarlane, P;
Whittaker, J;
Talmud, P;
+2 more...
Humphries, S;
Hingorani, A;
(2010)
Identification of Genes Associated with Qt Interval Using the 50k Cardio-Metabolic Snp Chip: Results from the Whitehall II Study.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/2938
Full text not available from this repository.
Shah, Tina;
Newcombe, Paul;
Smeeth, Liam;
Addo, Juliet;
Casas, Juan P;
Whittaker, John;
Miller, Michelle A;
Tinworth, Lorna;
Jeffery, Steve;
Strazzullo, Pasquale;
+2 more...
Cappuccio, Francesco P;
Hingorani, Aroon D;
(2010)
Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction.
Circulation Cardiovascular genetics, 3 (5).
pp. 436-444.
ISSN 1942-325X
DOI: https://doi.org/10.1161/CIRCGENETICS.110.957431
Full text not available from this repository.
Sofat, Reecha;
Casas, Juan P;
Kumari, Meena;
Talmud, Philippa J;
Ireland, Helen;
Kivimaki, Mika;
Marmot, Michael;
Hughes, Alun D;
Thom, Simon;
Ebrahim, Shah;
+5 more...
Whittaker, John C;
Smeeth, Liam;
Lawlor, Debbie A;
Humphries, Steve E;
Hingorani, Aroon D;
(2010)
Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.
Atherosclerosis, 213 (1).
pp. 184-190.
ISSN 0021-9150
DOI: https://doi.org/10.1016/j.atherosclerosis.2010.07.021
Full text not available from this repository.
2009
Balchin, I;
Whittaker, JC;
Lamont, RF;
Steer, PJ;
(2009)
The effect of exclusion of cases with unrecorded best estimate of gestational age on the estimates of preterm birth rate.
BJOG, 116 (9).
pp. 1218-1224.
ISSN 1470-0328
DOI: https://doi.org/10.1111/j.1471-0528.2009.02184.x
Full text not available from this repository.
Chapman, Juliet M;
Onnie, Clive M;
Prescott, Natalie J;
Fisher, Sheila A;
Mansfield, John C;
Mathew, Christopher G;
Lewis, Cathryn M;
Verzilli, Claudio J;
Whittaker, John C;
(2009)
Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease.
American journal of human genetics, 84 (2).
pp. 178-187.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2008.12.015
Full text not available from this repository.
Clarke, Mary C;
Tanskanen, Antti;
Huttunen, Matti;
Whittaker, John C;
Cannon, Mary;
(2009)
Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia.
The American journal of psychiatry, 166 (9).
pp. 1025-1030.
ISSN 0002-953X
DOI: https://doi.org/10.1176/appi.ajp.2009.08010031
Full text not available from this repository.
Doudney, K;
Grinham, J;
Whittaker, J;
Lynch, SA;
Thompson, D;
Moore, GE;
Copp, AJ;
Greene, NDE;
Stanier, P;
(2009)
Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects.
American journal of medical genetics Part A, 149A (7).
pp. 1585-1589.
ISSN 1552-4825
DOI: https://doi.org/10.1002/ajmg.a.32937
Full text not available from this repository.
Khalique, Lalarukh;
Ayhan, Ayse;
Whittaker, John C;
Singh, Naveena;
Jacobs, Ian J;
Gayther, Simon A;
Ramus, Susan J;
(2009)
The clonal evolution of metastases from primary serous epithelial ovarian cancers.
International journal of cancer Journal international du cancer, 124 (7).
pp. 1579-1586.
ISSN 0020-7136
DOI: https://doi.org/10.1002/ijc.24148
Full text not available from this repository.
Lunn, David J;
Best, Nicky;
Whittaker, John C;
(2009)
Generic reversible jump MCMC using graphical models.
Statistics and computing, 19 (4).
pp. 395-408.
ISSN 0960-3174
DOI: https://doi.org/10.1007/s11222-008-9100-0
Full text not available from this repository.
Mead, Simon;
Poulter, Mark;
Uphill, James;
Beck, John;
Whitfield, Jerome;
Webb, Thomas EF;
Campbell, Tracy;
Adamson, Gary;
Deriziotis, Pelagia;
Tabrizi, Sarah J;
+5 more...
Hummerich, Holger;
Verzilli, Claudio;
Alpers, Michael P;
Whittaker, John C;
Collinge, John;
(2009)
Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study.
Lancet neurology, 8 (1).
pp. 57-66.
ISSN 1474-4422
DOI: https://doi.org/10.1016/S1474-4422(08)70265-5
Mead, Simon;
Whitfield, Jerome;
Poulter, Mark;
Shah, Paresh;
Uphill, James;
Campbell, Tracy;
Al-Dujaily, Huda;
Hummerich, Holger;
Beck, Jon;
Mein, Charles A;
+4 more...
Verzilli, Claudio;
Whittaker, John;
Alpers, Michael P;
Collinge, John;
(2009)
A novel protective prion protein variant that colocalizes with kuru exposure.
The New England journal of medicine, 361 (21).
pp. 2056-2065.
ISSN 0028-4793
DOI: https://doi.org/10.1056/NEJMoa0809716
Newcombe, Paul J;
Verzilli, Claudio;
Casas, Juan P;
Hingorani, Aroon D;
Smeeth, Liam;
Whittaker, John C;
(2009)
Multilocus Bayesian meta-analysis of gene-disease associations.
American journal of human genetics, 84 (5).
pp. 567-580.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2009.04.001
Full text not available from this repository.
Nonyane, Bareng AS;
Nitsch, Dorothea;
Whittaker, John C;
Sofat, Reecha;
Smeeth, Liam;
Chakravarthy, Usha;
Fletcher, Astrid E;
(2009)
An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism.
Investigative ophthalmology & visual science, 51 (5).
pp. 2393-2402.
ISSN 0146-0404
DOI: https://doi.org/10.1167/iovs.09-4228
Full text not available from this repository.
Rao, Rohit;
Tah, Vikas;
Casas, Juan Pablo;
Hingorani, Aroon;
Whittaker, John;
Smeeth, Liam;
Sharma, Pankaj;
(2009)
Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke.
European neurology, 61 (2).
pp. 76-86.
ISSN 0014-3022
DOI: https://doi.org/10.1159/000177939
Full text not available from this repository.
Rhodes, B;
Hunnangkul, S;
Morris, DL;
Hsaio, L-C;
Graham, DS Cunninghame;
Nitsch, D;
Whittaker, JC;
Vyse, TJ;
(2009)
The heritability and genetics of complement C3 expression in UK SLE families.
Genes and immunity, 10 (5).
pp. 525-530.
ISSN 1466-4879
DOI: https://doi.org/10.1038/gene.2009.23
Full text not available from this repository.
Shah, S;
Drenos, F;
Shah, T;
Palmen, J;
Verzilli, C;
Sofat, R;
Kumari, M;
Kivamaki, M;
Pallas, J;
MacFarlane, P;
+4 more...
Whittaker, J;
Talmud, PJ;
Humphries, SE;
Hingorani, AD;
(2009)
IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY.
[Conference or Workshop Item]
https://doi.org/10.1016/j.atherosclerosis.2009.09.058
Full text not available from this repository.
Sovio, Ulla;
Bennett, Amanda J;
Millwood, Iona Y;
Molitor, John;
O'Reilly, Paul F;
Timpson, Nicholas J;
Kaakinen, Marika;
Laitinen, Jaana;
Haukka, Jari;
Pillas, Demetris;
+13 more...
Tzoulaki, Ioanna;
Molitor, Jassy;
Hoggart, Clive;
Coin, Lachlan JM;
Whittaker, John;
Pouta, Anneli;
Hartikainen, Anna-Liisa;
Freimer, Nelson B;
Widen, Elisabeth;
Peltonen, Leena;
Elliott, Paul;
McCarthy, Mark I;
Jarvelin, Marjo-Riitta;
(2009)
Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966.
PLoS genetics, 5 (3).
e1000409-.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1000409
Talmud, Philippa J;
Drenos, Fotios;
Shah, Sonia;
Shah, Tina;
Palmen, Jutta;
Verzilli, Claudio;
Gaunt, Tom R;
Pallas, Jacky;
Lovering, Ruth;
Li, Kawah;
+29 more...
Casas, Juan Pablo;
Sofat, Reecha;
Kumari, Meena;
Rodriguez, Santiago;
Johnson, Toby;
Newhouse, Stephen J;
Dominiczak, Anna;
Samani, Nilesh J;
Caulfield, Mark;
Sever, Peter;
Stanton, Alice;
Shields, Denis C;
Padmanabhan, Sandosh;
Melander, Olle;
Hastie, Claire;
Delles, Christian;
Ebrahim, Shah;
Marmot, Michael G;
Smith, George Davey;
Lawlor, Debbie A;
Munroe, Patricia B;
Day, Ian N;
Kivimaki, Mika;
Whittaker, John;
Humphries, Steve E;
Hingorani, Aroon D;
ASCOT investigators;
NORDIL investigators;
BRIGHT Consortium;
(2009)
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American journal of human genetics, 85 (5).
pp. 628-642.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2009.10.014
Full text not available from this repository.
Webb, TEF;
Whittaker, J;
Collinge, J;
Mead, S;
(2009)
Age of onset and death in inherited prion disease are heritable.
American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4).
pp. 496-501.
ISSN 1552-4841
DOI: https://doi.org/10.1002/ajmg.b.30844
Full text not available from this repository.
2008
Balchin, Imelda;
Whittaker, John C;
Lamont, Ronald F;
Steer, Philip J;
(2008)
Timing of planned cesarean delivery by racial group.
Obstetrics and gynecology, 111 (3).
pp. 659-666.
ISSN 0029-7844
DOI: https://doi.org/10.1097/AOG.0b013e318163cd55
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Barton, Sheila J;
Whittaker, John C;
(2008)
Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors.
Mass spectrometry reviews, 28 (1).
pp. 177-187.
ISSN 0277-7037
DOI: https://doi.org/10.1002/mas.20188
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Chadeau-Hyam, Marc;
Hoggart, Clive J;
O'Reilly, Paul F;
Whittaker, John C;
De Iorio, Maria;
Balding, David J;
(2008)
Fregene: simulation of realistic sequence-level data in populations and ascertained samples.
BMC bioinformatics, 9 (1).
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ISSN 1471-2105
DOI: https://doi.org/10.1186/1471-2105-9-364
Chapman, JM;
Onnie, C;
Prescott, N;
Fisher, S;
Lewis, C;
Mathew, C;
Verzilli, CJ;
Whittaker, JC;
(2008)
Searching for genotype-phenotype structure: Trying to understand Crohn's disease.
Annals of human genetics, 72.
p. 688.
ISSN 0003-4800
https://researchonline.lshtm.ac.uk/id/eprint/7101
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Chapman, Juliet;
Whittaker, John;
(2008)
Analysis of multiple SNPs in a candidate gene or region.
Genetic epidemiology, 32 (6).
pp. 560-566.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20330
Full text not available from this repository.
Cunninghame Graham, Deborah S;
Graham, Robert R;
Manku, Harinder;
Wong, Andrew K;
Whittaker, John C;
Gaffney, Patrick M;
Moser, Kathy L;
Rioux, John D;
Altshuler, David;
Behrens, Timothy W;
+1 more...
Vyse, Timothy J;
(2008)
Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus.
Nature genetics, 40 (1).
pp. 83-89.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng.2007.47
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Elmasry, K;
Ramus, S;
Whittaker, J;
Luo, Z;
Gammerman, A;
Lu, K;
Ayhan, A;
Singh, N;
McGluggage, G;
Jacobs, I;
+1 more...
Gayther, S;
(2008)
Genetic diagnosis and clinical outcome in patients with synchronous ovarian and endometrial cancer.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/8017
Full text not available from this repository.
Hoggart, Clive J;
Clark, Taane G;
De Iorio, Maria;
Whittaker, John C;
Balding, David J;
(2008)
Genome-wide significance for dense SNP and resequencing data.
Genetic epidemiology, 32 (2).
pp. 179-185.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20292
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Hoggart, Clive J;
Whittaker, John C;
De Iorio, Maria;
Balding, David J;
(2008)
Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies.
PLoS genetics, 4 (7).
e1000130-.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1000130
Hunnangkul, Saowalak;
Nitsch, Dorothea;
Rhodes, Benjamin;
Chadha, Sapna;
Roberton, Cheri A;
Pessôa-Lopes, Pedro;
Norsworthy, Peter J;
Fernando, Michelle MA;
Charles, Peter;
Mackworth-Young, Charles;
+3 more...
Isenberg, David A;
Whittaker, John C;
Vyse, Timothy J;
(2008)
Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus.
Arthritis and rheumatism, 58 (4).
pp. 1116-1124.
ISSN 0004-3591
DOI: https://doi.org/10.1002/art.23400
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Newcombe, PJ;
Verzilli, C;
Pablo-Casas, J;
Whittaker, J;
(2008)
Meta-analysis of gene/disease association studies.
Annals of human genetics, 72.
p. 689.
ISSN 0003-4800
https://researchonline.lshtm.ac.uk/id/eprint/7102
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Peck, George;
Smeeth, Liam;
Whittaker, John;
Casas, Juan Pablo;
Hingorani, Aroon;
Sharma, Pankaj;
(2008)
The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults.
PloS one, 3 (11).
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ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0003691
Ramus, Susan J;
Elmasry, Karim;
Luo, Zhiyuan;
Gammerman, Alex;
Lu, Karen;
Ayhan, Ayse;
Singh, Naveena;
McCluggage, W Glenn;
Jacobs, Ian J;
Whittaker, John C;
+1 more...
Gayther, Simon A;
(2008)
Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer.
Clinical cancer research, 14 (18).
pp. 5840-5848.
ISSN 1078-0432
DOI: https://doi.org/10.1158/1078-0432.CCR-08-0373
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Rhodes, B;
Meek, J;
Whittaker, JC;
Vyse, TJ;
(2008)
Quantification of the genetic component of basal C-reactive protein expression in SLE nuclear families.
Annals of human genetics, 72 (Pt 5).
pp. 611-620.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2008.00444.x
Full text not available from this repository.
Rhodes, B;
Meek, J;
Whittaker, JC;
Vyse, TJ;
(2008)
Quantification of the genetic component of basal C-reactive protein expression in SLE nuclear families.
Annals of human genetics, 72.
pp. 611-620.
ISSN 0003-4800
https://researchonline.lshtm.ac.uk/id/eprint/7103
Full text not available from this repository.
Rhodes, Benjamin;
Morris, David L;
Subrahmanyan, Lakshman;
Aubin, Cristin;
de Leon, Carlos F Mendes;
Kelly, Jeremiah F;
Evans, Dennis A;
Whittaker, John C;
Oksenberg, Jorge R;
De Jager, Philip L;
+1 more...
Vyse, Tim J;
(2008)
Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach.
Human genetics, 123 (6).
pp. 633-642.
ISSN 0340-6717
DOI: https://doi.org/10.1007/s00439-008-0517-5
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Verzilli, Claudio;
Shah, Tina;
Casas, Juan P;
Chapman, Juliet;
Sandhu, Manjinder;
Debenham, Sally L;
Boekholdt, Matthijs S;
Khaw, Kay Tee;
Wareham, Nicholas J;
Judson, Richard;
+10 more...
Benjamin, Emelia J;
Kathiresan, Sekar;
Larson, Martin G;
Rong, Jian;
Sofat, Reecha;
Humphries, Steve E;
Smeeth, Liam;
Cavalleri, Gianpiero;
Whittaker, John C;
Hingorani, Aroon D;
(2008)
Bayesian meta-analysis of genetic association studies with different sets of markers.
American journal of human genetics, 82 (4).
pp. 859-872.
ISSN 0002-9297
DOI: https://doi.org/10.1016/j.ajhg.2008.01.016
Full text not available from this repository.
Webb, TE;
Whittaker, J;
Collinge, J;
Mead, S;
(2008)
Age of onset and death in inherited prion disease are heritable.
American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4).
pp. 496-501.
ISSN 1552-4841
DOI: https://doi.org/10.1002/ajmg.b.30844
Full text not available from this repository.
2007
Apostolidou, S;
Abu-Amero, S;
O'Donoghue, K;
Frost, J;
Olafsdottir, O;
Chavele, KM;
Whittaker, JC;
Loughna, P;
Stanier, P;
Moore, GE;
(2007)
Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight.
Journal of molecular medicine (Berlin, Germany), 85 (4).
pp. 379-387.
ISSN 0946-2716
DOI: https://doi.org/10.1007/s00109-006-0131-8
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Ariyaratnam, Roshan;
Casas, Juan P;
Whittaker, John;
Smeeth, Liam;
Hingorani, Aroon D;
Sharma, Pankaj;
(2007)
Genetics of ischaemic stroke among persons of non-European descent: a meta-analysis of eight genes involving approximately 32,500 individuals.
PLoS medicine, 4 (4).
e131-.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.0040131
Baksh, M Fazil;
Balding, David J;
Vyse, Timothy J;
Whittaker, John C;
(2007)
Family-based association analysis with ordered categorical phenotypes, covariates and interactions.
Genetic epidemiology, 31 (1).
pp. 1-8.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20183
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Balchin, Imelda;
Whittaker, John C;
Patel, Roshni R;
Lamont, Ronald F;
Steer, Philip J;
(2007)
Racial variation in the association between gestational age and perinatal mortality: prospective study.
BMJ (Clinical research ed), 334 (7598).
833-.
ISSN 0959-8138
DOI: https://doi.org/10.1136/bmj.39132.482025.80
Barton, Sheila J;
Richardson, Sylvia;
Perkins, David N;
Bellahn, Inga;
Bryant, Trevor N;
Whittaker, John C;
(2007)
Using statistical models to identify factors that have a role in defining the abundance of ions produced by tandem MS.
Analytical chemistry, 79 (15).
pp. 5601-5607.
ISSN 0003-2700
DOI: https://doi.org/10.1021/ac0700272
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Campbell, Oona;
Coleman, Michel;
Cousens, Simon;
Doyle, Pat;
Elbourne, Diana;
Evans, Stephen;
Filteau, Suzanne;
Fine, Paul EM;
Glynn, Judith R;
Grundy, Emily;
+28 more...
Haines, Andy;
Hall, Andrew J;
Hayes, Richard;
Kenward, Mike;
Kirkwood, Betty;
Lamping, Donna L;
Lee, Kelley;
Leon, Dave;
Mabey, David;
McKee, Martin;
Meade, Tom;
Milligan, Paul;
Mills, Anne;
Patel, Vikram;
Peto, Julian;
Pocock, Stuart;
Prentice, Andrew;
Roberts, Ian;
Rodrigues, Laura C;
dos Santos Silva, Isabel;
Smeeth, Liam;
Sondorp, Egbert;
De Stavola, Bianca;
Timaeus, Ian M;
Walt, Gill;
Whittaker, John;
Wilkinson, Paul;
Zaba, Basia;
(2007)
Reed Elsevier and the arms trade revisited.
Lancet, 369 (9566).
987-.
ISSN 0140-6736
DOI: https://doi.org/10.1016/S0140-6736(07)60484-X
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Chapman, J;
Verzilli, C;
Whittaker, J;
(2007)
Large scale association studies: Implications for FDRs and a simple Bayesian alternative.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/8555
Full text not available from this repository.
Drenos, F;
Whittaker, JC;
Humphries, SE;
(2007)
The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk.
Annals of human genetics, 71 (Pt 5).
pp. 611-619.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1469-1809.2007.00359.x
Full text not available from this repository.
Hoggart, C;
de Iorio, M;
Whittaker, J;
Balding, D;
(2007)
Bayesian shrinkage priors for detecting multiple causal variants from genome-wide association studies.
Annals of human genetics, 71.
p. 557.
ISSN 0003-4800
https://researchonline.lshtm.ac.uk/id/eprint/8558
Full text not available from this repository.
Hoggart, CJ;
de Iorio, M;
Whittaker, JC;
Balding, DJ;
(2007)
Simultaneous analysis of genome-wide SNP data.
Genetic epidemiology, 31 (6).
p. 609.
ISSN 0741-0395
https://researchonline.lshtm.ac.uk/id/eprint/8559
Full text not available from this repository.
Hoggart, Clive J;
Chadeau-Hyam, Marc;
Clark, Taane G;
Lampariello, Riccardo;
Whittaker, John C;
De Iorio, Maria;
Balding, David J;
(2007)
Sequence-level population simulations over large genomic regions.
Genetics, 177 (3).
pp. 1725-1731.
ISSN 0016-6731
DOI: https://doi.org/10.1534/genetics.106.069088
Full text not available from this repository.
Sharma, P;
Whittaker, J;
Casas, JP;
Hingorani, AD;
Ariyaratnam, R;
(2007)
Genetics of ischaemic stroke in ethnic minorities.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/9688
Full text not available from this repository.
Van Mil, Saskia WC;
Milona, Alexandra;
Dixon, Peter H;
Mullenbach, Roman;
Geenes, Victoria L;
Chambers, Jenny;
Shevchuk, Vasylyna;
Moore, Gudrun E;
Lammert, Frank;
Glantz, Anna G;
+5 more...
Mattsson, Lars-Ake;
Whittaker, John;
Parker, Malcolm G;
White, Roger;
Williamson, Catherine;
(2007)
Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy.
Gastroenterology, 133 (2).
pp. 507-516.
ISSN 0016-5085
DOI: https://doi.org/10.1053/j.gastro.2007.05.015
Full text not available from this repository.
Verzilli, Claudio;
Chapman, Juliet;
Hingorani, Aroon;
Pablo-Casas, Juan;
Shah, Tina;
Smeeth, Liam;
Whittaker, John;
(2007)
Bayesian meta analysis of genetic association studies with different sets of markers.
Annals of human genetics, 71.
pp. 552-553.
ISSN 0003-4800
https://researchonline.lshtm.ac.uk/id/eprint/8490
Full text not available from this repository.
Whittaker, JC;
Chapman, J;
(2007)
Analysis of multiple SNPs in a candidate gene or region.
Genetic epidemiology, 31 (6).
p. 650.
ISSN 0741-0395
https://researchonline.lshtm.ac.uk/id/eprint/8560
Full text not available from this repository.
2006
Apostolidou, S;
Abu-Amero, S;
O'Donoghue, K;
Olafsdottir, O;
Chavele, KM;
Frost, J;
Whittaker, JC;
Loughna, P;
Stanier, P;
Moore, GE;
(2006)
Elevated maternal expression of the imprinted PHLDA2 gene is associated with low birth weight.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/9687
Full text not available from this repository.
Baksh, MF;
Balding, DJ;
Vyse, TJ;
Whittaker, JC;
(2006)
A likelihood ratio approach to family-based association studies with covariates.
Annals of human genetics, 70 (Pt 1).
pp. 131-139.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1529-8817.2005.00189.x
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Cunninghame Graham, DS;
Wong, AK;
McHugh, NJ;
Whittaker, JC;
Vyse, Timothy J;
(2006)
Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study.
Human molecular genetics, 15 (21).
pp. 3195-3205.
ISSN 0964-6906
DOI: https://doi.org/10.1093/hmg/ddl395
Full text not available from this repository.
Fletcher, Olivia;
Johnson, Nichola;
Palles, Claire;
dos Santos Silva, Isabel;
McCormack, Valerie;
Whittaker, John;
Ashworth, Alan;
Peto, Julian;
(2006)
Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk.
Journal of the National Cancer Institute, 98 (14).
pp. 1014-1018.
ISSN 0027-8874
DOI: https://doi.org/10.1093/jnci/djj268
Full text not available from this repository.
Lunn, David J;
Whittaker, John C;
Best, Nicky;
(2006)
A Bayesian toolkit for genetic association studies.
Genetic epidemiology, 30 (3).
pp. 231-247.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20140
Full text not available from this repository.
Nitsch, Dorothea;
Molokhia, Mariam;
Smeeth, Liam;
DeStavola, Bianca L;
Whittaker, John C;
Leon, David A;
(2006)
Limits to causal inference based on Mendelian randomization: a comparison with randomized controlled trials.
American journal of epidemiology, 163 (5).
pp. 397-403.
ISSN 0002-9262
DOI: https://doi.org/10.1093/aje/kwj062
Full text not available from this repository.
Rohrmann, Sabine;
Linseisen, Jakob;
Boshuizen, Hendriek C;
Whittaker, John;
Agudo, Antonio;
Vineis, Paolo;
Boffetta, Paolo;
Jensen, Majken K;
Olsen, Anja;
Overvad, Kim;
+34 more...
Tjønneland, Anne;
Boutron-Ruault, Marie-Christine;
Clavel-Chapelon, Françoise;
Bergmann, Manuela M;
Boeing, Heiner;
Allen, Naomi;
Key, Tim;
Bingham, Sheila;
Khaw, Kay-Tee;
Kyriazi, Georgia;
Soukara, Stavroula;
Trichopoulou, Antonia;
Panico, Salvatore;
Palli, Domenico;
Sieri, Sabina;
Tumino, Rosario;
Peeters, Petra HM;
Bueno-de-Mesquita, H Bas;
Büchner, Frederike L;
Gram, Inger Torhild;
Lund, Eiliv;
Ardanaz, Eva;
Chirlaque, María-Dolores;
Dorronsoro, Miren;
Pérez, Maria-José Sánchez;
Quirós, Jose R;
Berglund, Göran;
Janzon, Lars;
Rasmuson, Torgny;
Weinehall, Lars;
Ferrari, Pietro;
Jenab, Mazda;
Norat, Teresa;
Riboli, Elio;
(2006)
Ethanol intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC).
American journal of epidemiology, 164 (11).
pp. 1103-1114.
ISSN 0002-9262
DOI: https://doi.org/10.1093/aje/kwj326
Full text not available from this repository.
Underwood, SL;
Christoforou, A;
Thomson, PA;
Wray, NR;
Tenesa, A;
Whittaker, J;
Adams, RA;
Le Hellard, S;
Morris, SW;
Blackwood, DHR;
+3 more...
Muir, WJ;
Porteous, DJ;
Evans, KL;
(2006)
Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.
Molecular psychiatry, 11 (4).
pp. 384-394.
ISSN 1359-4184
DOI: https://doi.org/10.1038/sj.mp.4001786
Full text not available from this repository.
Verzilli, Claudio J;
Stallard, Nigel;
Whittaker, John C;
(2006)
Bayesian graphical models for genomewide association studies.
American journal of human genetics, 79 (1).
pp. 100-112.
ISSN 0002-9297
DOI: https://doi.org/10.1086/505313
Full text not available from this repository.
Waldron, ERB;
Whittaker, JC;
Balding, DJ;
(2006)
Fine mapping of disease genes via haplotype clustering.
Genetic epidemiology, 30 (2).
pp. 170-179.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20134
Full text not available from this repository.
2005
Christoforou, A;
Underwood, SL;
Hellard, SL;
Wray, NR;
Morris, SW;
Tenesa, A;
Thomson, PA;
Whittaker, J;
Blackwood, DH;
Muir, WJ;
+2 more...
Porteous, DJ;
Evans, KL;
(2005)
Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.
American journal of medical genetics Part B, Neuropsychiatric genetics, 138B (1).
p. 47.
ISSN 1552-4841
https://researchonline.lshtm.ac.uk/id/eprint/12455
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Hubner, Norbert;
Wallace, Caroline A;
Zimdahl, Heike;
Petretto, Enrico;
Schulz, Herbert;
Maciver, Fiona;
Mueller, Michael;
Hummel, Oliver;
Monti, Jan;
Zidek, Vaclav;
+12 more...
Musilova, Alena;
Kren, Vladimir;
Causton, Helen;
Game, Laurence;
Born, Gabriele;
Schmidt, Sabine;
Müller, Anita;
Cook, Stuart A;
Kurtz, Theodore W;
Whittaker, John;
Pravenec, Michal;
Aitman, Timothy J;
(2005)
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.
Nature genetics, 37 (3).
pp. 243-253.
ISSN 1061-4036
DOI: https://doi.org/10.1038/ng1522
Full text not available from this repository.
Kelly, Patrick J;
Stallard, Nigel;
Whittaker, John C;
(2005)
Statistical design and analysis of pharmacogenetic trials.
Statistics in medicine, 24 (10).
pp. 1495-1508.
ISSN 0277-6715
DOI: https://doi.org/10.1002/sim.2052
Full text not available from this repository.
Pardi, F;
Lewis, CM;
Whittaker, JC;
(2005)
SNP selection for association studies: maximizing power across SNP choice and study size.
Annals of human genetics, 69 (Pt 6).
pp. 733-746.
ISSN 0003-4800
DOI: https://doi.org/10.1111/j.1529-8817.2005.00202.x
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Pardi, Fabio;
Sibly, Richard M;
Wilkinson, MJ;
Whittaker, John C;
(2005)
On the structural differences between markers and genomic AC microsatellites.
Journal of molecular evolution, 60 (5).
pp. 688-693.
ISSN 0022-2844
DOI: https://doi.org/10.1007/s00239-004-0274-6
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Russell, AI;
Cunninghame Graham, DS;
Chadha, S;
Roberton, C;
Fernandez-Hart, T;
Griffiths, B;
D'Cruz, D;
Nitsch, D;
Whittaker, JC;
Vyse, TJ;
(2005)
No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE.
Genes and immunity, 6 (5).
pp. 422-429.
ISSN 1466-4879
DOI: https://doi.org/10.1038/sj.gene.6364222
Full text not available from this repository.
Verzilli, Claudio J;
Stallard, Nigel;
Whittaker, John C;
(2005)
Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions.
Genetic epidemiology, 28 (4).
pp. 313-325.
ISSN 0741-0395
DOI: https://doi.org/10.1002/gepi.20072
Full text not available from this repository.
Verzilli, Claudio J;
Whittaker, John C;
Stallard, Nigel;
Chasman, Daniel;
(2005)
A Hierarchical Bayesian Model for Predicting the Functional Consequences of Amino-Acid Polymorphisms.
Applied statistics, 54 (1).
pp. 191-206.
ISSN 0035-9254
DOI: https://doi.org/10.1111/j.1467-9876.2005.00478.x
Full text not available from this repository.
Waldron, ERB;
Whittaker, JC;
Balding, DJ;
(2005)
A spatial clustering approach to fine-mapping of disease genes.
[Conference or Workshop Item]
https://researchonline.lshtm.ac.uk/id/eprint/6482
Full text not available from this repository.
2004
Balchin, Imelda;
Whittaker, John C;
Steer, Philip J;
Lamont, Ronald F;
(2004)
Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate.
BJOG, 111 (2).
pp. 160-163.
ISSN 1470-0328
DOI: https://doi.org/10.1046/j.1471-0528.2003.00026.x
Full text not available from this repository.
Morris, AP;
Whittaker, JC;
Balding, DJ;
(2004)
Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data.
American journal of human genetics, 74 (5).
pp. 945-953.
ISSN 0002-9297
DOI: https://doi.org/10.1086/420773
Full text not available from this repository.
Russell, Andrew I;
Cunninghame Graham, Deborah S;
Shepherd, Christopher;
Roberton, Cheri A;
Whittaker, John;
Meeks, John;
Powell, Richard J;
Isenberg, David A;
Walport, Mark J;
Vyse, Timothy J;
(2004)
Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus.
Human molecular genetics, 13 (1).
pp. 137-147.
ISSN 0964-6906
DOI: https://doi.org/10.1093/hmg/ddh021
Full text not available from this repository.
2003
Byng, MC;
Whittaker, JC;
Cuthbert, AP;
Mathew, CG;
Lewis, CM;
(2003)
SNP subset selection for genetic association studies.
Annals of human genetics, 67 (Pt 6).
pp. 543-556.
ISSN 0003-4800
DOI: https://doi.org/10.1046/j.1529-8817.2003.00055.x
Full text not available from this repository.
Byng, Martyn C;
Fisher, Sheila A;
Lewis, Cathryn M;
Whittaker, John C;
Framingham Heart Study;
(2003)
Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study.
BMC genetics, 4 Supp (Suppl ).
S4-.
ISSN 1471-2156
DOI: https://doi.org/10.1186/1471-2156-4-S1-S4
Denham, Michael C;
Whittaker, John C;
(2003)
A Bayesian approach to disease gene location using allelic association.
Biostatistics (Oxford, England), 4 (3).
pp. 399-409.
ISSN 1465-4644
DOI: https://doi.org/10.1093/biostatistics/4.3.399
Full text not available from this repository.
Morris, Andrew P;
Whittaker, John C;
Xu, Chun-Fang;
Hosking, Louise K;
Balding, David J;
(2003)
Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity.
Proceedings of the National Academy of Sciences of the United States of America, 100 (23).
pp. 13442-13446.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.2235031100
Full text not available from this repository.
Sibly, Richard M;
Meade, Andrew;
Boxall, Nicola;
Wilkinson, Michael J;
Corne, Dave W;
Whittaker, John C;
(2003)
The structure of interrupted human AC microsatellites.
Molecular biology and evolution, 20 (3).
pp. 453-459.
ISSN 0737-4038
DOI: https://doi.org/10.1093/molbev/msg056
Full text not available from this repository.
Whittaker, John C;
Gharani, Neda;
Hindmarsh, Peter;
McCarthy, Mark I;
(2003)
Estimation and testing of parent-of-origin effects for quantitative traits.
American journal of human genetics, 72 (4).
pp. 1035-1039.
ISSN 0002-9297
DOI: https://doi.org/10.1086/374382
Full text not available from this repository.
Whittaker, John C;
Harbord, Roger M;
Boxall, Nicola;
Mackay, Ian;
Dawson, Gary;
Sibly, Richard M;
(2003)
Likelihood-based estimation of microsatellite mutation rates.
Genetics, 164 (2).
pp. 781-787.
ISSN 0016-6731
DOI: https://doi.org/10.1093/genetics/164.2.781
Full text not available from this repository.
2002
Lange, C;
Whittaker, JC;
(2002)
Generalised estimating equations: a hybrid approach for mean parameters in multivariate regression models.
Statistical Modelling, 2.
pp. 163-181.
ISSN 1477-0342
https://researchonline.lshtm.ac.uk/id/eprint/13386
Full text not available from this repository.
Lange, C;
Whittaker, JC;
(2002)
Model selection for quasi-likelihood: a new approach.
In: Gregori, D; Cameci, G; Friedl, H; Ferligoi, A; Wedlin, A, (eds.)
Correlated Data Modeling.
Economia/Ricerche, Collana.
https://researchonline.lshtm.ac.uk/id/eprint/13385
Full text not available from this repository.
Morris, AP;
Whittaker, JC;
Balding, DJ;
(2002)
Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies.
American journal of human genetics, 70 (3).
pp. 686-707.
ISSN 0002-9297
DOI: https://doi.org/10.1086/339271
Full text not available from this repository.
2001
Lange, C;
Whittaker, JC;
(2001)
Mapping quantitative trait Loci using generalized estimating equations.
Genetics, 159 (3).
pp. 1325-1337.
ISSN 0016-6731
DOI: https://doi.org/10.1093/genetics/159.3.1325
Full text not available from this repository.
Lange, C;
Whittaker, JC;
(2001)
On prediction of genetic values in marker-assisted selection.
Genetics, 159 (3).
pp. 1375-1381.
ISSN 0016-6731
DOI: https://doi.org/10.1093/genetics/159.3.1375
Full text not available from this repository.
Lewis, CM;
Pinêl, T;
Whittaker, JC;
Handyside, AH;
(2001)
Controlling misdiagnosis errors in preimplantation genetic diagnosis: a comprehensive model encompassing extrinsic and intrinsic sources of error.
Human reproduction (Oxford, England), 16 (1).
pp. 43-50.
ISSN 0268-1161
DOI: https://doi.org/10.1093/humrep/16.1.43
Full text not available from this repository.
Sibly, RM;
Whittaker, JC;
Talbot, M;
(2001)
A maximum-likelihood approach to fitting equilibrium models of microsatellite evolution.
Molecular biology and evolution, 18 (3).
pp. 413-417.
ISSN 0737-4038
DOI: https://doi.org/10.1093/oxfordjournals.molbev.a003817
Full text not available from this repository.
Whittaker, JC;
(2001)
Marker assisted selection and introgression.
In: Balding, DJ; Bishop, M; Cannings, C, (eds.)
Handbook of Statistical Genetics.
Wiley.
https://researchonline.lshtm.ac.uk/id/eprint/13387
Full text not available from this repository.
Whittaker, JC;
Morris, AP;
(2001)
Family-based tests of association and/or linkage.
Annals of human genetics, 65 (Pt 5).
pp. 407-419.
ISSN 0003-4800
DOI: https://doi.org/10.1017/S0003480001008818
Full text not available from this repository.