Items where Author or Contributor is "Whittaker, John"

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Number of items: 150.

2016

Charoen, Pimphen; Nitsch, Dorothea; Engmann, Jorgen; Shah, Tina; White, Jonathan; Zabaneh, Delilah; Jefferis, Barbara; Wannamethee, Goya; Whincup, Peter; Mulick Cassidy, Amy; +14 more... Gaunt, Tom; Day, Ian; McLachlan, Stela; Price, Jacqueline; Kumari, Meena; Kivimaki, Mika; Brunner, Eric; Langenberg, Claudia; Ben-Shlomo, Yoav; Hingorani, Aroon; Whittaker, John; Pablo Casas, Juan; Dudbridge, Frank; UCLEB Consortium; (2016) Mendelian Randomisation study of the influence of eGFR on coronary heart disease. Scientific reports, 6 (1). 28514-. ISSN 2045-2322 DOI: https://doi.org/10.1038/srep28514
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Swerdlow, Daniel I; Kuchenbaecker, Karoline B; Shah, Sonia; Sofat, Reecha; Holmes, Michael V; White, Jon; Mindell, Jennifer S; Kivimaki, Mika; Brunner, Eric J; Whittaker, John C; +2 more... Casas, Juan P; Hingorani, Aroon D; (2016) Selecting instruments for Mendelian randomization in the wake of genome-wide association studies. International journal of epidemiology, 45 (5). pp. 1600-1616. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyw088
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2015

Moore, Gudrun E; Ishida, Miho; Demetriou, Charalambos; Al-Olabi, Lara; Leon, Lydia J; Thomas, Anna C; Abu-Amero, Sayeda; Frost, Jennifer M; Stafford, Jaime L; Chaoqun, Yao; +12 more... Duncan, Andrew J; Baigel, Rachel; Brimioulle, Marina; Iglesias-Platas, Isabel; Apostolidou, Sophia; Aggarwal, Reena; Whittaker, John C; Syngelaki, Argyro; Nicolaides, Kypros H; Regan, Lesley; Monk, David; Stanier, Philip; (2015) The role and interaction of imprinted genes in human fetal growth. Philosophical transactions of the Royal Society of London Series B, Biological sciences, 370 (1663). 20140074-. ISSN 0962-8436 DOI: https://doi.org/10.1098/rstb.2014.0074
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Nelson, Matthew R; Tipney, Hannah; Painter, Jeffery L; Shen, Judong; Nicoletti, Paola; Shen, Yufeng; Floratos, Aris; Sham, Pak Chung; Li, Mulin Jun; Wang, Junwen; +3 more... Cardon, Lon R; Whittaker, John C; Sanseau, Philippe; (2015) The support of human genetic evidence for approved drug indications. Nature genetics, 47 (8). pp. 856-860. ISSN 1061-4036 DOI: https://doi.org/10.1038/ng.3314 Full text not available from this repository.

Nüesch, Eveline; Dale, Caroline; Palmer, Tom M; White, Jon; Keating, Brendan J; van Iperen, Erik Pa; Goel, Anuj; Padmanabhan, Sandosh; Asselbergs, Folkert W; EPIC-Netherland Investigators; +71 more... Verschuren, WM; Wijmenga, C; Van der Schouw, YT; Onland-Moret, NC; Lange, Leslie A; Hovingh, GK; Sivapalaratnam, Suthesh; Morris, Richard W; Whincup, Peter H; Wannamethe, Goya S; Gaunt, Tom R; Ebrahim, Shah; Steel, Laura; Nair, Nikhil; Reiner, Alexander P; Kooperberg, Charles; Wilson, James F; Bolton, Jennifer L; McLachlan, Stela; Price, Jacqueline F; Strachan, Mark Wj; Robertson, Christine M; Kleber, Marcus E; Delgado, Graciela; März, Winfried; Melander, Olle; Dominiczak, Anna F; Farrall, Martin; Watkins, Hugh; Leusink, Maarten; Maitland-van der Zee, Anke H; de Groot, Mark Ch; Dudbridge, Frank; Hingorani, Aroon; Ben-Shlomo, Yoav; Lawlor, Debbie A; UCLEB Investigators; Amuzu, A; Caufield, M; Cavadino, A; Cooper, J; Davies, TL; IN Day; Drenos, F; Engmann, J; Finan, C; Giambartolomei, C; Hardy, R; Humphries, SE; Hypponen, E; Kivimaki, M; Kuh, D; Kumari, M; Ong, K; Plagnol, V; Power, C; Richards, M; Shah, S; Shah, T; Sofat, R; Talmud, PJ; Wareham, N; Warren, H; Whittaker, JC; Wong, A; Zabaneh, D; Davey Smith, George; Wells, Jonathan C; Leon, David A; Holmes, Michael V; Casas, Juan P; (2015) Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis. International journal of epidemiology, 45 (6). pp. 1927-1937. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyv074
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Xu, C-F; Johnson, T; Garcia-Donas, J; Choueiri, TK; Sternberg, CN; Davis, ID; Bing, N; Deen, KC; Xue, Z; McCann, L; +6 more... Esteban, E; Whittaker, JC; Spraggs, CF; Rodríguez-Antona, C; Pandite, LN; Motzer, RJ; (2015) IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma. British journal of cancer, 112 (7). pp. 1190-1198. ISSN 0007-0920 DOI: https://doi.org/10.1038/bjc.2015.64
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2014

Futema, Marta; Shah, Sonia; Cooper, Jackie A; Li, KaWah; Whittall, Ros A; Sharifi, Mahtab; Goldberg, Olivia; Drogari, Euridiki; Mollaki, Vasiliki; Wiegman, Albert; +16 more... Defesche, Joep; D'Agostino, Maria N; D'Angelo, Antonietta; Rubba, Paolo; Fortunato, Giuliana; Waluś-Miarka, Małgorzata; Hegele, Robert A; Aderayo Bamimore, Mary; Durst, Ronen; Leitersdorf, Eran; Mulder, Monique T; Roeters van Lennep, Jeanine E; Sijbrands, Eric JG; Whittaker, John C; Talmud, Philippa J; Humphries, Steve E; (2014) Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries. Clinical chemistry, 61 (1). pp. 231-238. ISSN 0009-9147 DOI: https://doi.org/10.1373/clinchem.2014.231365 Full text not available from this repository.

Holmes, Michael V; Dale, Caroline E; Zuccolo, Luisa; Silverwood, Richard J; Guo, Yiran; Ye, Zheng; Prieto-Merino, David; Dehghan, Abbas; Trompet, Stella; Wong, Andrew; +146 more... Cavadino, Alana; Drogan, Dagmar; Padmanabhan, Sandosh; Li, Shanshan; Yesupriya, Ajay; Leusink, Maarten; Sundstrom, Johan; Hubacek, Jaroslav A; Pikhart, Hynek; Swerdlow, Daniel I; Panayiotou, Andrie G; Borinskaya, Svetlana A; Finan, Chris; Shah, Sonia; Kuchenbaecker, Karoline B; Shah, Tina; Engmann, Jorgen; Folkersen, Lasse; Eriksson, Per; Ricceri, Fulvio; Melander, Olle; Sacerdote, Carlotta; Gamble, Dale M; Rayaprolu, Sruti; Ross, Owen A; McLachlan, Stela; Vikhireva, Olga; Sluijs, Ivonne; Scott, Robert A; Adamkova, Vera; Flicker, Leon; Bockxmeer, Frank M van; Power, Christine; Marques-Vidal, Pedro; Meade, Tom; Marmot, Michael G; Ferro, Jose M; Paulos-Pinheiro, Sofia; Humphries, Steve E; Talmud, Philippa J; Mateo Leach, Irene; Verweij, Niek; Linneberg, Allan; Skaaby, Tea; Doevendans, Pieter A; Cramer, Maarten J; van der Harst, Pim; Klungel, Olaf H; Dowling, Nicole F; Dominiczak, Anna F; Kumari, Meena; Nicolaides, Andrew N; Weikert, Cornelia; Boeing, Heiner; Ebrahim, Shah; Gaunt, Tom R; Price, Jackie F; Lannfelt, Lars; Peasey, Anne; Kubinova, Ruzena; Pajak, Andrzej; Malyutina, Sofia; Voevoda, Mikhail I; Tamosiunas, Abdonas; Maitland-van der Zee, Anke H; Norman, Paul E; Hankey, Graeme J; Bergmann, Manuela M; Hofman, Albert; Franco, Oscar H; Cooper, Jackie; Palmen, Jutta; Spiering, Wilko; de Jong, Pim A; Kuh, Diana; Hardy, Rebecca; Uitterlinden, Andre G; Ikram, M Arfan; Ford, Ian; Hyppönen, Elina; Almeida, Osvaldo P; Wareham, Nicholas J; Khaw, Kay-Tee; Hamsten, Anders; Husemoen, Lise Lotte N; Tjønneland, Anne; Tolstrup, Janne S; Rimm, Eric; Beulens, Joline WJ; Verschuren, WM Monique; Onland-Moret, N Charlotte; Hofker, Marten H; Wannamethee, S Goya; Whincup, Peter H; Morris, Richard; Vicente, Astrid M; Watkins, Hugh; Farrall, Martin; Jukema, J Wouter; Meschia, James; Cupples, L Adrienne; Sharp, Stephen J; Fornage, Myriam; Kooperberg, Charles; LaCroix, Andrea Z; Dai, James Y; Lanktree, Matthew B; Siscovick, David S; Jorgenson, Eric; Spring, Bonnie; Coresh, Josef; Li, Yun R; Buxbaum, Sarah G; Schreiner, Pamela J; Ellison, R Curtis; Tsai, Michael Y; Patel, Sanjay R; Redline, Susan; Johnson, Andrew D; Hoogeveen, Ron C; Hakonarson, Hakon; Rotter, Jerome I; Boerwinkle, Eric; de Bakker, Paul IW; Kivimaki, Mika; Asselbergs, Folkert W; Sattar, Naveed; Lawlor, Debbie A; Whittaker, John; Davey Smith, George; Mukamal, Kenneth; Psaty, Bruce M; Wilson, James G; Lange, Leslie A; Hamidovic, Ajna; Hingorani, Aroon D; Nordestgaard, Børge G; Bobak, Martin; Leon, David A; Langenberg, Claudia; Palmer, Tom M; Reiner, Alex P; Keating, Brendan J; Dudbridge, Frank; Casas, Juan P; InterAct Consortium; (2014) Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ (Clinical research ed), 349 (jul10). g4164-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.g4164
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Silverwood, Richard J; Holmes, Michael V; Dale, Caroline E; Lawlor, Debbie A; Whittaker, John C; Smith, George Davey; Leon, David A; Palmer, Tom; Keating, Brendan J; Zuccolo, Luisa; +3 more... Casas, Juan P; Dudbridge, Frank; Alcohol-ADH1B Consortium; (2014) Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits. International journal of epidemiology, 43 (6). pp. 1781-1790. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyu187
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Swerdlow, Daniel I; Preiss, David; Kuchenbaecker, Karoline B; Holmes, Michael V; Engmann, Jorgen EL; Shah, Tina; Sofat, Reecha; Stender, Stefan; Johnson, Paul CD; Scott, Robert A; +126 more... Leusink, Maarten; Verweij, Niek; Sharp, Stephen J; Guo, Yiran; Giambartolomei, Claudia; Chung, Christina; Peasey, Anne; Amuzu, Antoinette; Li, KaWah; Palmen, Jutta; Howard, Philip; Cooper, Jackie A; Drenos, Fotios; Li, Yun R; Lowe, Gordon; Gallacher, John; Stewart, Marlene CW; Tzoulaki, Ioanna; Buxbaum, Sarah G; van der A, Daphne L; Forouhi, Nita G; Onland-Moret, N Charlotte; van der Schouw, Yvonne T; Schnabel, Renate B; Hubacek, Jaroslav A; Kubinova, Ruzena; Baceviciene, Migle; Tamosiunas, Abdonas; Pajak, Andrzej; Topor-Madry, Roman; Stepaniak, Urszula; Malyutina, Sofia; Baldassarre, Damiano; Sennblad, Bengt; Tremoli, Elena; de Faire, Ulf; Veglia, Fabrizio; Ford, Ian; Jukema, J Wouter; Westendorp, Rudi GJ; de Borst, Gert Jan; de Jong, Pim A; Algra, Ale; Spiering, Wilko; Maitland-van der Zee, Anke H; Klungel, Olaf H; de Boer, Anthonius; Doevendans, Pieter A; Eaton, Charles B; Robinson, Jennifer G; Duggan, David; DIAGRAM Consortium; MAGIC Consortium; InterAct Consortium; Kjekshus, John; Downs, John R; Gotto, Antonio M; Keech, Anthony C; Marchioli, Roberto; Tognoni, Gianni; Sever, Peter S; Poulter, Neil R; Waters, David D; Pedersen, Terje R; Amarenco, Pierre; Nakamura, Haruo; McMurray, John JV; Lewsey, James D; Chasman, Daniel I; Ridker, Paul M; Maggioni, Aldo P; Tavazzi, Luigi; Ray, Kausik K; Seshasai, Sreenivasa Rao Kondapally; Manson, JoAnn E; Price, Jackie F; Whincup, Peter H; Morris, Richard W; Lawlor, Debbie A; Smith, George Davey; Ben-Shlomo, Yoav; Schreiner, Pamela J; Fornage, Myriam; Siscovick, David S; Cushman, Mary; Kumari, Meena; Wareham, Nick J; Verschuren, WM Monique; Redline, Susan; Patel, Sanjay R; Whittaker, John C; Hamsten, Anders; Delaney, Joseph A; Dale, Caroline; Gaunt, Tom R; Wong, Andrew; Kuh, Diana; Hardy, Rebecca; Kathiresan, Sekar; Castillo, Berta A; van der Harst, Pim; Brunner, Eric J; Tybjaerg-Hansen, Anne; Marmot, Michael G; Krauss, Ronald M; Tsai, Michael; Coresh, Josef; Hoogeveen, Ronald C; Psaty, Bruce M; Lange, Leslie A; Hakonarson, Hakon; Dudbridge, Frank; Humphries, Steve E; Talmud, Philippa J; Kivimäki, Mika; Timpson, Nicholas J; Langenberg, Claudia; Asselbergs, Folkert W; Voevoda, Mikhail; Bobak, Martin; Pikhart, Hynek; Wilson, James G; Reiner, Alex P; Keating, Brendan J; Hingorani, Aroon D; Sattar, Naveed; (2014) HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials. Lancet, 385 (9965). pp. 351-361. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(14)61183-1
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Talmud, Philippa J; Cooper, Jackie A; Morris, Richard W; Dudbridge, Frank; Shah, Tina; Engmann, Jorgen; Dale, Caroline; White, Jon; McLachlan, Stela; Zabaneh, Delilah; +21 more... Wong, Andrew; Ong, Ken K; Gaunt, Tom; Holmes, Michael V; Lawlor, Debbie A; Richards, Marcus; Hardy, Rebecca; Kuh, Diana; Wareham, Nicholas; Langenberg, Claudia; Ben-Shlomo, Yoav; Wannamethee, S Goya; Strachan, Mark WJ; Kumari, Meena; Whittaker, John C; Drenos, Fotios; Kivimaki, Mika; Hingorani, Aroon D; Price, Jacqueline F; Humphries, Steve E; UCLEB Consortium; (2014) Sixty-five common genetic variants and prediction of type 2 diabetes. Diabetes, 64 (5). pp. 1830-1840. ISSN 0012-1797 DOI: https://doi.org/10.2337/db14-1504
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Vimaleswaran, Karani S; Cavadino, Alana; Berry, Diane J; LifeLines Cohort Study investigators; Jorde, Rolf; Dieffenbach, Aida Karina; Lu, Chen; Alves, Alexessander Couto; Heerspink, Hiddo J Lambers; Tikkanen, Emmi; +98 more... Eriksson, Joel; Wong, Andrew; Mangino, Massimo; Jablonski, Kathleen A; Nolte, Ilja M; Houston, Denise K; Ahluwalia, Tarunveer Singh; van der Most, Peter J; Pasko, Dorota; Zgaga, Lina; Thiering, Elisabeth; Vitart, Veronique; Fraser, Ross M; Huffman, Jennifer E; de Boer, Rudolf A; Schöttker, Ben; Saum, Kai-Uwe; McCarthy, Mark I; Dupuis, Josée; Herzig, Karl-Heinz; Sebert, Sylvain; Pouta, Anneli; Laitinen, Jaana; Kleber, Marcus E; Navis, Gerjan; Lorentzon, Mattias; Jameson, Karen; Arden, Nigel; Cooper, Jackie A; Acharya, Jayshree; Hardy, Rebecca; Raitakari, Olli; Ripatti, Samuli; Billings, Liana K; Lahti, Jari; Osmond, Clive; Penninx, Brenda W; Rejnmark, Lars; Lohman, Kurt K; Paternoster, Lavinia; Stolk, Ronald P; Hernandez, Dena G; Byberg, Liisa; Hagström, Emil; Melhus, Håkan; Ingelsson, Erik; Mellström, Dan; Ljunggren, Osten; Tzoulaki, Ioanna; McLachlan, Stela; Theodoratou, Evropi; Tiesler, Carla MT; Jula, Antti; Navarro, Pau; Wright, Alan F; Polasek, Ozren; International Consortium for Blood Pressure (ICBP); Cohorts for Heart and Aging Research in Genomic Epidemiology (CH; Global Blood Pressure Genetics (Global BPGen) consortium; Caroline Hayward; Wilson, James F; Rudan, Igor; Salomaa, Veikko; Heinrich, Joachim; Campbell, Harry; Price, Jacqueline F; Karlsson, Magnus; Lind, Lars; Michaëlsson, Karl; Bandinelli, Stefania; Frayling, Timothy M; Hartman, Catharina A; Sørensen, Thorkild IA; Kritchevsky, Stephen B; Langdahl, Bente Lomholt; Eriksson, Johan G; Florez, Jose C; Spector, Tim D; Lehtimäki, Terho; Kuh, Diana; Humphries, Steve E; Cooper, Cyrus; Ohlsson, Claes; März, Winfried; de Borst, Martin H; Kumari, Meena; Kivimaki, Mika; Wang, Thomas J; Power, Chris; Brenner, Hermann; Grimnes, Guri; van der Harst, Pim; Snieder, Harold; Hingorani, Aroon D; Pilz, Stefan; Whittaker, John C; Järvelin, Marjo-Riitta; Hyppönen, Elina; (2014) Association of vitamin D status with arterial blood pressure and hypertension risk: a mendelian randomisation study. The lancet Diabetes & endocrinology, 2 (9). pp. 719-729. ISSN 2213-8587 DOI: https://doi.org/10.1016/S2213-8587(14)70113-5
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2013

Chan, Kenneth; Patel, Riyaz S; Newcombe, Paul; Nelson, Christopher P; Qasim, Atif; Epstein, Stephen E; Burnett, Susan; Vaccarino, Viola L; Zafari, A Maziar; Shah, Svati H; +42 more... Anderson, Jeffrey L; Carlquist, John F; Hartiala, Jaana; Allayee, Hooman; Hinohara, Kunihiko; Lee, Bok-Soo; Erl, Anna; Ellis, Katrina L; Goel, Anuj; Schaefer, Arne S; El Mokhtari, Nour Eddine; Goldstein, Benjamin A; Hlatky, Mark A; Go, Alan S; Shen, Gong-Qing; Gong, Yan; Pepine, Carl; Laxton, Ross C; Whittaker, John C; Tang, WH Wilson; Johnson, Julie A; Wang, Qing K; Assimes, Themistocles L; Nöthlings, Ute; Farrall, Martin; Watkins, Hugh; Richards, A Mark; Cameron, Vicky A; Muendlein, Axel; Drexel, Heinz; Koch, Werner; Park, Jeong Euy; Kimura, Akinori; Shen, Wei-feng; Simpson, Iain A; Hazen, Stanley L; Horne, Benjamin D; Hauser, Elizabeth R; Quyyumi, Arshed A; Reilly, Muredach P; Samani, Nilesh J; Ye, Shu; (2013) Association between the chromosome 9p21 locus and angiographic coronary artery disease burden: a collaborative meta-analysis. Journal of the American College of Cardiology, 61 (9). pp. 957-970. ISSN 0735-1097 DOI: https://doi.org/10.1016/j.jacc.2012.10.051 Full text not available from this repository.

Dixon, Peter H; Wadsworth, Christopher A; Chambers, Jennifer; Donnelly, Jennifer; Cooley, Sharon; Buckley, Rebecca; Mannino, Ramona; Jarvis, Sheba; Syngelaki, Argyro; Geenes, Victoria; +13 more... Paul, Priyadarshini; Sothinathan, Meera; Kubitz, Ralf; Lammert, Frank; Tribe, Rachel M; Ch'ng, Chin Lye; Marschall, Hanns-Ulrich; Glantz, Anna; Khan, Shahid A; Nicolaides, Kypros; Whittaker, John; Geary, Michael; Williamson, Catherine; (2013) A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy. The American journal of gastroenterology, 109 (1). pp. 76-84. ISSN 0002-9270 DOI: https://doi.org/10.1038/ajg.2013.406
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Hu, Youna; Li, Li; Ehm, Margaret G; Bing, Nan; Song, Kijoung; Nelson, Matthew R; Talmud, Philippa J; Hingorani, Aroon D; Kumari, Meena; Kivimäki, Mika; +6 more... Xu, Chun-Fang; Waterworth, Dawn M; Whittaker, John C; Abecasis, Gonçalo R; Spino, Cathie; Kang, Hyun Min; (2013) The benefits of using genetic information to design prevention trials. American journal of human genetics, 92 (4). pp. 547-557. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2013.03.003 Full text not available from this repository.

Khan, Tauseef A; Shah, Tina; Prieto, David; Zhang, Weili; Price, Jackie; Fowkes, Gerald R; Cooper, Jackie; Talmud, Philippa J; Humphries, Steve E; Sundstrom, Johan; +39 more... Hubacek, Jaroslav A; Ebrahim, Shah; Lawlor, Debbie A; Ben-Shlomo, Yoav; Abdollahi, Mohammad R; Slooter, Arjen JC; Szolnoki, Zoltan; Sandhu, Manjinder; Wareham, Nicholas; Frikke-Schmidt, Ruth; Tybjærg-Hansen, Anne; Fillenbaum, Gerda; Heijmans, Bastiaan T; Katsuya, Tomohiro; Gromadzka, Grazyna; Singleton, Andrew; Ferrucci, Luigi; Hardy, John; Worrall, Bradford; Rich, Stephen S; Matarin, Mar; Whittaker, John; Gaunt, Tom R; Whincup, Peter; Morris, Richard; Deanfield, John; Donald, Ann; Davey Smith, George; Kivimaki, Mika; Kumari, Meena; Smeeth, Liam; Khaw, Kay-Tee; Nalls, Michael; Meschia, James; Sun, Kai; Hui, Rutai; Day, Ian; Hingorani, Aroon D; Casas, Juan P; (2013) Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals. International journal of epidemiology, 42 (2). pp. 475-492. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyt034 Full text not available from this repository.

Shah, Sonia; Casas, Juan-Pablo; Drenos, Fotios; Whittaker, John; Deanfield, John; Swerdlow, Daniel I; Holmes, Michael V; Kivimaki, Mika; Langenberg, Claudia; Wareham, Nick; +13 more... Gertow, Karl; Sennblad, Bengt; Strawbridge, Rona J; Baldassarre, Damiano; Veglia, Fabrizio; Tremoli, Elena; Gigante, Bruna; de Faire, Ulf; Kumari, Meena; Talmud, Philippa J; Hamsten, Anders; Humphries, Steve E; Hingorani, Aroon D; (2013) Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis. Circulation Cardiovascular genetics, 6 (1). pp. 63-72. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.112.963140 Full text not available from this repository.

Shah, Tina; Engmann, Jorgen; Dale, Caroline; Shah, Sonia; White, Jon; Giambartolomei, Claudia; McLachlan, Stela; Zabaneh, Delilah; Cavadino, Alana; Finan, Chris; +37 more... Wong, Andrew; Amuzu, Antoinette; Ong, Ken; Gaunt, Tom; Holmes, Michael V; Warren, Helen; Swerdlow, Daniel I; Davies, Teri-Louise; Drenos, Fotios; Cooper, Jackie; Sofat, Reecha; Caulfield, Mark; Ebrahim, Shah; Lawlor, Debbie A; Talmud, Philippa J; Humphries, Steve E; Power, Christine; Hypponen, Elina; Richards, Marcus; Hardy, Rebecca; Kuh, Diana; Wareham, Nicholas; Langenberg, Claudia; Ben-Shlomo, Yoav; Day, Ian N; Whincup, Peter; Morris, Richard; Strachan, Mark WJ; Price, Jacqueline; Kumari, Meena; Kivimaki, Mika; Plagnol, Vincent; Dudbridge, Frank; Whittaker, John C; Casas, Juan P; Hingorani, Aroon D; UCLEB Consortium; (2013) Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium. PloS one, 8 (8). e71345-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0071345
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Shah, Tina; Zabaneh, Delilah; Gaunt, Tom; Swerdlow, Daniel I; Shah, Sonia; Talmud, Philippa J; Day, Ian N; Whittaker, John; Holmes, Michael V; Sofat, Reecha; +5 more... Humphries, Steve E; Kivimaki, Mika; Kumari, Meena; Hingorani, Aroon D; Casas, Juan P; (2013) Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. Circulation Cardiovascular genetics, 6 (2). pp. 163-170. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.112.964254 Full text not available from this repository.

Talmud, Philippa J; Shah, Sonia; Whittall, Ros; Futema, Marta; Howard, Philip; Cooper, Jackie A; Harrison, Seamus C; Li, Kawah; Drenos, Fotios; Karpe, Frederik; +9 more... Neil, H Andrew W; Descamps, Olivier S; Langenberg, Claudia; Lench, Nicholas; Kivimaki, Mika; Whittaker, John; Hingorani, Aroon D; Kumari, Meena; Humphries, Steve E; (2013) Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet, 381 (9874). pp. 1293-1301. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(12)62127-8 Full text not available from this repository.

Vimaleswaran, KS; Cavadino, A; Berry, DJ; Whittaker, JC; Power, C; Järvelin, M-R; Hyppönen, E; (2013) Genetic association analysis of vitamin D pathway with obesity traits. International journal of obesity and related metabolic disorders, 37 (10). pp. 1399-1406. ISSN 0307-0565 DOI: https://doi.org/10.1038/ijo.2013.6 Full text not available from this repository.

Vimaleswaran, Karani S; Berry, Diane J; Lu, Chen; Tikkanen, Emmi; Pilz, Stefan; Hiraki, Linda T; Cooper, Jason D; Dastani, Zari; Li, Rui; Houston, Denise K; +49 more... Wood, Andrew R; Michaëlsson, Karl; Vandenput, Liesbeth; Zgaga, Lina; Yerges-Armstrong, Laura M; McCarthy, Mark I; Dupuis, Josée; Kaakinen, Marika; Kleber, Marcus E; Jameson, Karen; Arden, Nigel; Raitakari, Olli; Viikari, Jorma; Lohman, Kurt K; Ferrucci, Luigi; Melhus, Håkan; Ingelsson, Erik; Byberg, Liisa; Lind, Lars; Lorentzon, Mattias; Salomaa, Veikko; Campbell, Harry; Dunlop, Malcolm; Mitchell, Braxton D; Herzig, Karl-Heinz; Pouta, Anneli; Hartikainen, Anna-Liisa; Genetic Investigation of Anthropometric Traits-GIANT Consortium; Streeten, Elizabeth A; Theodoratou, Evropi; Jula, Antti; Wareham, Nicholas J; Ohlsson, Claes; Frayling, Timothy M; Kritchevsky, Stephen B; Spector, Timothy D; Richards, J Brent; Lehtimäki, Terho; Ouwehand, Willem H; Kraft, Peter; Cooper, Cyrus; März, Winfried; Power, Chris; Loos, Ruth JF; Wang, Thomas J; Järvelin, Marjo-Riitta; Whittaker, John C; Hingorani, Aroon D; Hyppönen, Elina; (2013) Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS medicine, 10 (2). e1001383-. ISSN 1549-1277 DOI: https://doi.org/10.1371/journal.pmed.1001383
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Warren, Helen; Casas, Juan-Pablo; Hingorani, Aroon; Dudbridge, Frank; Whittaker, John; (2013) Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores. Genetic epidemiology, 38 (1). pp. 72-83. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.21777 Full text not available from this repository.

2012

Asselbergs, Folkert W; Guo, Yiran; van Iperen, Erik PA; Sivapalaratnam, Suthesh; Tragante, Vinicius; Lanktree, Matthew B; Lange, Leslie A; Almoguera, Berta; Appelman, Yolande E; Barnard, John; +161 more... Baumert, Jens; Beitelshees, Amber L; Bhangale, Tushar R; Chen, Yii-Der Ida; Gaunt, Tom R; Gong, Yan; Hopewell, Jemma C; Johnson, Toby; Kleber, Marcus E; Langaee, Taimour Y; Li, Mingyao; Li, Yun R; Liu, Kiang; McDonough, Caitrin W; Meijs, Matthijs FL; Middelberg, Rita PS; Musunuru, Kiran; Nelson, Christopher P; O'Connell, Jeffery R; Padmanabhan, Sandosh; Pankow, James S; Pankratz, Nathan; Rafelt, Suzanne; Rajagopalan, Ramakrishnan; Romaine, Simon PR; Schork, Nicholas J; Shaffer, Jonathan; Shen, Haiqing; Smith, Erin N; Tischfield, Sam E; van der Most, Peter J; van Vliet-Ostaptchouk, Jana V; Verweij, Niek; Volcik, Kelly A; Zhang, Li; Bailey, Kent R; Bailey, Kristian M; Bauer, Florianne; Boer, Jolanda MA; Braund, Peter S; Burt, Amber; Burton, Paul R; Buxbaum, Sarah G; Chen, Wei; Cooper-Dehoff, Rhonda M; Cupples, L Adrienne; deJong, Jonas S; Delles, Christian; Duggan, David; Fornage, Myriam; Furlong, Clement E; Glazer, Nicole; Gums, John G; Hastie, Claire; Holmes, Michael V; Illig, Thomas; Kirkland, Susan A; Kivimaki, Mika; Klein, Ronald; Klein, Barbara E; Kooperberg, Charles; Kottke-Marchant, Kandice; Kumari, Meena; LaCroix, Andrea Z; Mallela, Laya; Murugesan, Gurunathan; Ordovas, Jose; Ouwehand, Willem H; Post, Wendy S; Saxena, Richa; Scharnagl, Hubert; Schreiner, Pamela J; Shah, Tina; Shields, Denis C; Shimbo, Daichi; Srinivasan, Sathanur R; Stolk, Ronald P; Swerdlow, Daniel I; Taylor, Herman A; Topol, Eric J; Toskala, Elina; van Pelt, Joost L; van Setten, Jessica; Yusuf, Salim; Whittaker, John C; Zwinderman, AH; LifeLines Cohort Study; Anand, Sonia S; Balmforth, Anthony J; Berenson, Gerald S; Bezzina, Connie R; Boehm, Bernhard O; Boerwinkle, Eric; Casas, Juan P; Caulfield, Mark J; Clarke, Robert; Connell, John M; Cruickshanks, Karen J; Davidson, Karina W; Day, Ian NM; de Bakker, Paul IW; Doevendans, Pieter A; Dominiczak, Anna F; Hall, Alistair S; Hartman, Catharina A; Hengstenberg, Christian; Hillege, Hans L; Hofker, Marten H; Humphries, Steve E; Jarvik, Gail P; Johnson, Julie A; Kaess, Bernhard M; Kathiresan, Sekar; Koenig, Wolfgang; Lawlor, Debbie A; März, Winfried; Melander, Olle; Mitchell, Braxton D; Montgomery, Grant W; Munroe, Patricia B; Murray, Sarah S; Newhouse, Stephen J; Onland-Moret, N Charlotte; Poulter, Neil; Psaty, Bruce; Redline, Susan; Rich, Stephen S; Rotter, Jerome I; Schunkert, Heribert; Sever, Peter; Shuldiner, Alan R; Silverstein, Roy L; Stanton, Alice; Thorand, Barbara; Trip, Mieke D; Tsai, Michael Y; van der Harst, Pim; van der Schoot, Ellen; van der Schouw, Yvonne T; Verschuren, WM Monique; Watkins, Hugh; Wilde, Arthur AM; Wolffenbuttel, Bruce HR; Whitfield, John B; Hovingh, G Kees; Ballantyne, Christie M; Wijmenga, Cisca; Reilly, Muredach P; Martin, Nicholas G; Wilson, James G; Rader, Daniel J; Samani, Nilesh J; Reiner, Alex P; Hegele, Robert A; Kastelein, John JP; Hingorani, Aroon D; Talmud, Philippa J; Hakonarson, Hakon; Elbers, Clara C; Keating, Brendan J; Drenos, Fotios; (2012) Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. American journal of human genetics, 91 (5). pp. 823-838. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2012.08.032 Full text not available from this repository.

Bacanu, S-A; Whittaker, JC; Nelson, MR; (2012) How informative is a negative finding in a small pharmacogenetic study? The pharmacogenomics journal, 12 (2). pp. 93-95. ISSN 1470-269X DOI: https://doi.org/10.1038/tpj.2011.58
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Gaunt, Tom R; Shah, Sonia; Nelson, Christopher P; Drenos, Fotios; Braund, Peter S; Adeniran, Ismail; Folkersen, Lasse; Lawlor, Debbie A; Casas, Juan-Pablo; Amuzu, Antoinette; +15 more... Kivimaki, Mika; Whittaker, John; Eriksson, Per; Zhang, Henggui; Hancox, Jules C; Tomaszewski, Maciej; Burton, Paul R; Tobin, Martin D; Humphries, Steve E; Talmud, Philippa J; Macfarlane, Peter W; Hingorani, Aroon D; Samani, Nilesh J; Kumari, Meena; Day, Ian NM; (2012) Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip. Circulation Cardiovascular genetics, 5 (6). pp. 630-638. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.112.962852 Full text not available from this repository.

Ishida, Miho; Monk, David; Duncan, Andrew J; Abu-Amero, Sayeda; Chong, Jiehan; Ring, Susan M; Pembrey, Marcus E; Hindmarsh, Peter C; Whittaker, John C; Stanier, Philip; +1 more... Moore, Gudrun E; (2012) Maternal inheritance of a promoter variant in the imprinted PHLDA2 gene significantly increases birth weight. American journal of human genetics, 90 (4). pp. 715-719. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2012.02.021 Full text not available from this repository.

McCarthy, Linda C; Newcombe, Paul J; Whittaker, John C; Wurzelmann, John I; Fries, Michael A; Burnham, Nancy R; Cai, Gengqian; Stinnett, Sandra W; Trivedi, Trupti M; Xu, Chun-Fang; (2012) Predictive models of choroidal neovascularization and geographic atrophy incidence applied to clinical trial design. American journal of ophthalmology, 154 (3). 568-578.e12. ISSN 0002-9394 DOI: https://doi.org/10.1016/j.ajo.2012.03.021 Full text not available from this repository.

Mead, Simon; Uphill, James; Beck, John; Poulter, Mark; Campbell, Tracy; Lowe, Jessica; Adamson, Gary; Hummerich, Holger; Klopp, Norman; Rückert, Ina-Maria; +11 more... Wichmann, H-Erich; Azazi, Dhoyazan; Plagnol, Vincent; Pako, Wandagi H; Whitfield, Jerome; Alpers, Michael P; Whittaker, John; Balding, David J; Zerr, Inga; Kretzschmar, Hans; Collinge, John; (2012) Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. Human molecular genetics, 21 (8). pp. 1897-1906. ISSN 0964-6906 DOI: https://doi.org/10.1093/hmg/ddr607 Full text not available from this repository.

Nelson, Matthew R; Wegmann, Daniel; Ehm, Margaret G; Kessner, Darren; St Jean, Pamela; Verzilli, Claudio; Shen, Judong; Tang, Zhengzheng; Bacanu, Silviu-Alin; Fraser, Dana; +21 more... Warren, Liling; Aponte, Jennifer; Zawistowski, Matthew; Liu, Xiao; Zhang, Hao; Zhang, Yong; Li, Jun; Li, Yun; Li, Li; Woollard, Peter; Topp, Simon; Hall, Matthew D; Nangle, Keith; Wang, Jun; Abecasis, Gonçalo; Cardon, Lon R; Zöllner, Sebastian; Whittaker, John C; Chissoe, Stephanie L; Novembre, John; Mooser, Vincent; (2012) An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (New York, NY), 337 (6090). pp. 100-104. ISSN 0036-8075 DOI: https://doi.org/10.1126/science.1217876 Full text not available from this repository.

Newcombe, Paul J; Reck, Brian H; Sun, Jielin; Platek, Greg T; Verzilli, Claudio; Kader, A Karim; Kim, Seong-Tae; Hsu, Fang-Chi; Zhang, Zheng; Zheng, S Lilly; +6 more... Mooser, Vincent E; Condreay, Lynn D; Spraggs, Colin F; Whittaker, John C; Rittmaster, Roger S; Xu, Jianfeng; (2012) A comparison of Bayesian and frequentist approaches to incorporating external information for the prediction of prostate cancer risk. Genetic epidemiology, 36 (1). pp. 71-83. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.21600 Full text not available from this repository.

Rubio, Justin P; Topp, Simon; Warren, Liling; St Jean, Pamela L; Wegmann, Daniel; Kessner, Darren; Novembre, John; Shen, Judong; Fraser, Dana; Aponte, Jennifer; +7 more... Nangle, Keith; Cardon, Lon R; Ehm, Margaret G; Chissoe, Stephanie L; Whittaker, John C; Nelson, Matthew R; Mooser, Vincent E; (2012) Deep sequencing of the LRRK2 gene in 14,002 individuals reveals evidence of purifying selection and independent origin of the p.Arg1628Pro mutation in Europe. Human mutation, 33 (7). pp. 1087-1098. ISSN 1059-7794 DOI: https://doi.org/10.1002/humu.22075 Full text not available from this repository.

Shah, Sonia; Casas, Juan P; Gaunt, Tom R; Cooper, Jackie; Drenos, Fotios; Zabaneh, Delilah; Swerdlow, Daniel I; Shah, Tina; Sofat, Reecha; Palmen, Jutta; +10 more... Kumari, Meena; Kivimaki, Mika; Ebrahim, Shah; Smith, George Davey; Lawlor, Debbie A; Talmud, Philippa J; Whittaker, John; Day, Ian NM; Hingorani, Aroon D; Humphries, Steve E; (2012) Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies. European heart journal, 34 (13). pp. 972-981. ISSN 0195-668X DOI: https://doi.org/10.1093/eurheartj/ehs243 Full text not available from this repository.

Sofat, Reecha; Casas, Juan P; Webster, Andrew R; Bird, Alan C; Mann, Samantha S; Yates, John RW; Moore, Anthony T; Sepp, Tiina; Cipriani, Valentina; Bunce, Catey; +43 more... Khan, Jane C; Shahid, Humma; Swaroop, Anand; Abecasis, Gonçalo; Branham, Kari EH; Zareparsi, Sepideh; Bergen, Arthur A; Klaver, Caroline CW; Baas, Dominique C; Zhang, Kang; Chen, Yuhong; Gibbs, Daniel; Weber, Bernhard HF; Keilhauer, Claudia N; Fritsche, Lars G; Lotery, Andrew; Cree, Angela J; Griffiths, Helen L; Bhattacharya, Shomi S; Chen, Li L; Jenkins, Sharon A; Peto, Tunde; Lathrop, Mark; Leveillard, Thierry; Gorin, Michael B; Weeks, Daniel E; Ortube, Maria Carolina; Ferrell, Robert E; Jakobsdottir, Johanna; Conley, Yvette P; Rahu, Mati; Seland, Johan H; Soubrane, Gisele; Topouzis, Fotis; Vioque, Jesus; Tomazzoli, Laura; Young, Ian; Whittaker, John; Chakravarthy, Usha; de Jong, Paulus TVM; Smeeth, Liam; Fletcher, Astrid; Hingorani, Aroon D; (2012) Complement factor H genetic variant and age-related macular degeneration: effect size, modifiers and relationship to disease subtype. International journal of epidemiology, 41 (1). pp. 250-262. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyr204 Full text not available from this repository.

Song, K; Nelson, MR; Aponte, J; Manas, ES; Bacanu, S-A; Yuan, X; Kong, X; Cardon, L; Mooser, VE; Whittaker, JC; +1 more... Waterworth, DM; (2012) Sequencing of Lp-PLA2-encoding PLA2G7 gene in 2000 Europeans reveals several rare loss-of-function mutations. The pharmacogenomics journal, 12 (5). pp. 425-431. ISSN 1470-269X DOI: https://doi.org/10.1038/tpj.2011.20
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Warren, Liling L; Li, Li; Nelson, Matthew R; Ehm, Margaret G; Shen, Judong; Fraser, Dana J; Aponte, Jennifer L; Nangle, Keith L; Slater, Andrew J; Woollard, Peter M; +12 more... Hall, Matt D; Topp, Simon D; Yuan, Xin; Cardon, Lon R; Chissoe, Stephanie L; Mooser, Vincent; Morris, Andrew D; Palmer, Colin NA; Perry, John R; Frayling, Timothy M; Whittaker, John C; Waterworth, Dawn M; (2012) Deep resequencing unveils genetic architecture of ADIPOQ and identifies a novel low-frequency variant strongly associated with adiponectin variation. Diabetes, 61 (5). pp. 1297-1301. ISSN 0012-1797 DOI: https://doi.org/10.2337/db11-0985
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2011

Angelakopoulou, Aspasia; Shah, Tina; Sofat, Reecha; Shah, Sonia; Berry, Diane J; Cooper, Jackie; Palmen, Jutta; Tzoulaki, Ioanna; Wong, Andrew; Jefferis, Barbara J; +35 more... Maniatis, Nikolas; Drenos, Fotios; Gigante, Bruna; Hardy, Rebecca; Laxton, Ross C; Leander, Karin; Motterle, Anna; Simpson, Iain A; Smeeth, Liam; Thomson, Andy; Verzilli, Claudio; Kuh, Diana; Ireland, Helen; Deanfield, John; Caulfield, Mark; Wallace, Chris; Samani, Nilesh; Munroe, Patricia B; Lathrop, Mark; Fowkes, F Gerry R; Marmot, Michael; Whincup, Peter H; Whittaker, John C; de Faire, Ulf; Kivimaki, Mika; Kumari, Meena; Hypponen, Elina; Power, Chris; Humphries, Steve E; Talmud, Philippa J; Price, Jackie; Morris, Richard W; Ye, Shu; Casas, Juan P; Hingorani, Aroon D; (2011) Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. European heart journal, 33 (3). pp. 393-407. ISSN 0195-668X DOI: https://doi.org/10.1093/eurheartj/ehr225
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Bacanu, Silviu-Alin; Nelson, Matthew R; Whittaker, John C; (2011) Comparison of methods and sampling designs to test for association between rare variants and quantitative traits. Genetic epidemiology, 35 (4). pp. 226-235. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20570 Full text not available from this repository.

Balchin, Imelda; Whittaker, John C; Lamont, Ronald F; Steer, Philip J; (2011) Maternal and fetal characteristics associated with meconium-stained amniotic fluid. Obstetrics and gynecology, 117 (4). pp. 828-835. ISSN 0029-7844 DOI: https://doi.org/10.1097/AOG.0b013e3182117a26 Full text not available from this repository.

Brown, Andrew Anand; Richardson, Sylvia; Whittaker, John; (2011) Application of the Lasso to Expression Quantitative Trait Loci Mapping. Statistical applications in genetics and molecular biology, 10 (1). ISSN 2194-6302 DOI: https://doi.org/10.2202/1544-6115.1606 Full text not available from this repository.

C Reactive Protein Coronary Heart Disease Genetics Collaboration; Wensley, Frances; Gao, Pei; Burgess, Stephen; Kaptoge, Stephen; Di Angelantonio, Emanuele; Shah, Tina; Engert, James C; Clarke, Robert; Davey-Smith, George; +12 more... Nordestgaard, Børge G; Saleheen, Danish; Samani, Nilesh J; Sandhu, Manjinder; Anand, Sonia; Pepys, Mark B; Smeeth, Liam; Whittaker, John; Casas, Juan Pablo; Thompson, Simon G; Hingorani, Aroon D; Danesh, John; (2011) Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ, 342 (feb15). d548-. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj.d548
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De Iorio, Maria; Newcombe, Paul J; Tachmazidou, Ioanna; Verzilli, Claudio J; Whittaker, John C; (2011) Bayesian semiparametric meta-analysis for genetic association studies. Genetic epidemiology, 35 (5). pp. 333-340. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20581 Full text not available from this repository.

Dixon, PH; Wadsworth, CA; Chambers, J; Donnelly, JC; Cooley, SM; Kubitz, R; Lammert, F; Marschall, HU; Glantz, A; Khan, SA; +3 more... Whittaker, J; Geary, M; Williamson, C; (2011) DOES COMMON GENETIC VARIATION AROUND THE PREGNANE-X RECEPTOR INFLUENCE SUSCEPTIBILITY TO INTRAHEPATIC CHOLESTASIS OF PREGNANCY? [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/18504 Full text not available from this repository.

Holmes, Michael V; Newcombe, Paul; Hubacek, Jaroslav A; Sofat, Reecha; Ricketts, Sally L; Cooper, Jackie; Breteler, Monique MB; Bautista, Leonelo E; Sharma, Pankaj; Whittaker, John C; +36 more... Smeeth, Liam; Fowkes, F Gerald R; Algra, Ale; Shmeleva, Veronika; Szolnoki, Zoltan; Roest, Mark; Linnebank, Michael; Zacho, Jeppe; Nalls, Michael A; Singleton, Andrew B; Ferrucci, Luigi; Hardy, John; Worrall, Bradford B; Rich, Stephen S; Matarin, Mar; Norman, Paul E; Flicker, Leon; Almeida, Osvaldo P; van Bockxmeer, Frank M; Shimokata, Hiroshi; Khaw, Kay-Tee; Wareham, Nicholas J; Bobak, Martin; Sterne, Jonathan AC; Smith, George Davey; Talmud, Philippa J; van Duijn, Cornelia; Humphries, Steve E; Price, Jackie F; Ebrahim, Shah; Lawlor, Debbie A; Hankey, Graeme J; Meschia, James F; Sandhu, Manjinder S; Hingorani, Aroon D; Casas, Juan P; (2011) Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Lancet, 378 (9791). pp. 584-594. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(11)60872-6
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Hyppönen, Elina; Fararouei, Mohammad; Sovio, Ulla; Hartikainen, Anna-Liisa; Pouta, Anneli; Robertson, Claire; Whittaker, John C; Jarvelin, Marjo-Riitta; (2011) High-dose vitamin D supplements are not associated with linear growth in a large Finnish cohort. The Journal of nutrition, 141 (5). pp. 843-848. ISSN 0022-3166 DOI: https://doi.org/10.3945/jn.110.133009 Full text not available from this repository.

Li, Li; Li, Yun; Browning, Sharon R; Browning, Brian L; Slater, Andrew J; Kong, Xiangyang; Aponte, Jennifer L; Mooser, Vincent E; Chissoe, Stephanie L; Whittaker, John C; +2 more... Nelson, Matthew R; Ehm, Margaret Gelder; (2011) Performance of genotype imputation for rare variants identified in exons and flanking regions of genes. PloS one, 6 (9). e24945-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0024945
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Shah, Sonia; Nelson, Christopher P; Gaunt, Tom R; van der Harst, Pim; Barnes, Timothy; Braund, Peter S; Lawlor, Debbie A; Casas, Juan-Pablo; Padmanabhan, Sandosh; Drenos, Fotios; +30 more... Kivimaki, Mika; Talmud, Philippa J; Humphries, Steve E; Whittaker, John; Morris, Richard W; Whincup, Peter H; Dominiczak, Anna; Munroe, Patricia B; Johnson, Toby; Goodall, Alison H; Cambien, Francois; Diemert, Patrick; Hengstenberg, Christian; Ouwehand, Willem H; Felix, Janine F; Glazer, Nicole L; Tomaszewski, Maciej; Burton, Paul R; Tobin, Martin D; van Veldhuisen, Dirk J; de Boer, Rudolf A; Navis, Gerjan; van Gilst, Wiek H; Mayosi, Bongani M; Thompson, John R; Kumari, Meena; MacFarlane, Peter W; Day, Ian NM; Hingorani, Aroon D; Samani, Nilesh J; (2011) Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy. Circulation Cardiovascular genetics, 4 (6). pp. 626-635. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.111.960203 Full text not available from this repository.

Spraggs, Colin F; Budde, Laura R; Briley, Linda P; Bing, Nan; Cox, Charles J; King, Karen S; Whittaker, John C; Mooser, Vincent E; Preston, Alaknanda J; Stein, Steven H; +1 more... Cardon, Lon R; (2011) HLA-DQA1*02:01 is a major risk factor for lapatinib-induced hepatotoxicity in women with advanced breast cancer. Journal of clinical oncology, 29 (6). pp. 667-673. ISSN 0732-183X DOI: https://doi.org/10.1200/JCO.2010.31.3197 Full text not available from this repository.

Talmud, PJ; Cooper, JA; Gaunt, T; Holmes, MV; Shah, S; Palmen, J; Drenos, F; Shah, T; Kumari, M; Kivimaki, M; +6 more... Whittaker, J; Lawlor, DA; Day, IN; Hingorani, AD; Casas, JP; Humphries, SE; (2011) Variants of ADRA2A are associated with fasting glucose, blood pressure, body mass index and type 2 diabetes risk: meta-analysis of four prospective studies. Diabetologia, 54 (7). pp. 1710-1719. ISSN 0012-186X DOI: https://doi.org/10.1007/s00125-011-2108-6
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Wadsworth, Christopher A; Dixon, Peter H; Wong, Jason H; Chapman, Michael H; McKay, Siobhan C; Sharif, Amar; Spalding, Duncan R; Pereira, Stephen P; Thomas, Howard C; Taylor-Robinson, Simon D; +3 more... Whittaker, John; Williamson, Catherine; Khan, Shahid A; (2011) Genetic factors in the pathogenesis of cholangiocarcinoma. Digestive diseases (Basel, Switzerland), 29 (1). pp. 93-97. ISSN 0257-2753 DOI: https://doi.org/10.1159/000324688 Full text not available from this repository.

Xu, Chun-Fang; Bing, Nan X; Ball, Howard A; Rajagopalan, Dilip; Sternberg, Cora N; Hutson, Thomas E; de Souza, Paul; Xue, Zhengyu G; McCann, Lauren; King, Karen S; +6 more... Ragone, Leigh J; Whittaker, John C; Spraggs, Colin F; Cardon, Lon R; Mooser, Vincent E; Pandite, Lini N; (2011) Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. Journal of clinical oncology, 29 (18). pp. 2557-2564. ISSN 0732-183X DOI: https://doi.org/10.1200/JCO.2010.32.9110 Full text not available from this repository.

Zabaneh, Delilah; Gaunt, Tom R; Kumari, Meena; Drenos, Fotios; Shah, Sonia; Berry, Diane; Power, Chris; Hypponen, Elina; Shah, Tina; Palmen, Jutta; +18 more... Pallas, Jacky; Talmud, Philippa J; Casas, Juan Pablo; Sofat, Reecha; Lowe, Gordon; Rumley, Ann; Morris, Richard W; Whincup, Peter H; Rodriguez, Santiago; Ebrahim, Shah; Marmot, Michael G; Smith, George Davey; Lawlor, Debbie A; Kivimaki, Mika; Whittaker, John; Hingorani, Aroon D; Day, Ian N; Humphries, Steve E; (2011) Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip. Annals of human genetics, 75 (4). pp. 456-467. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1469-1809.2011.00654.x Full text not available from this repository.

Zabaneh, Delilah; Kumari, Meena; Sandhu, Manj; Wareham, Nick; Wainwright, Nick; Papamarkou, Theodore; Hopewell, Jemma; Clarke, Robert; Li, KaWah; Palmen, Jutta; +16 more... Talmud, Philippa J; Kronenberg, Florian; Lamina, Claudia; Summerer, Monika; Paulweber, Bernhard; Price, Jackie; Fowkes, Gerry; Stewart, Marlene; Drenos, Fotios; Shah, Sonia; Shah, Tina; Casas, Juan-Pablo; Kivimaki, Mika; Whittaker, John; Hingorani, Aroon D; Humphries, Steve E; (2011) Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts. Atherosclerosis, 217 (2). pp. 447-451. ISSN 0021-9150 DOI: https://doi.org/10.1016/j.atherosclerosis.2011.04.015 Full text not available from this repository.

2010

Burgess, Stephen; Thompson, Simon G; CRP CHD Genetics Collaboration; Burgess, S; Thompson, SG; Andrews, G; Samani, NJ; Hall, A; Whincup, P; Morris, R; +107 more... Lawlor, DA; Davey Smith, G; Timpson, N; Ebrahim, S; Ben-Shlomo, Y; Davey Smith, G; Timpson, N; Brown, M; Ricketts, S; Sandhu, M; Reiner, A; Psaty, B; Lange, L; Cushman, M; Hung, J; Thompson, P; Beilby, J; Warrington, N; Palmer, LJ; Nordestgaard, BG; Tybjaerg-Hansen, A; Zacho, J; Wu, C; Lowe, G; Tzoulaki, I; Kumari, M; Sandhu, M; Yamamoto, JF; Chiodini, B; Franzosi, M; Hankey, GJ; Jamrozik, K; Palmer, L; Rimm, E; Pai, J; Psaty, B; Heckbert, S; Bis, J; Anand, S; Engert, J; Collins, R; Clarke, R; Melander, O; Berglund, G; Ladenvall, P; Johansson, L; Jansson, J-H; Hallmans, G; Hingorani, A; Humphries, S; Rimm, E; Manson, J; Pai, J; Watkins, H; Clarke, R; Hopewell, J; Saleheen, D; Frossard, R; Danesh, J; Sattar, N; Robertson, M; Shepherd, J; Schaefer, E; Hofman, A; Witteman, JCM; Kardys, I; Ben-Shlomo, Y; Davey Smith, G; Timpson, N; de Faire, U; Bennet, A; Sattar, N; Ford, I; Packard, C; Kumari, M; Manson, J; Lawlor, Debbie A; Davey Smith, George; Anand, S; Collins, R; Casas, JP; Danesh, J; Davey Smith, G; Franzosi, M; Hingorani, A; Lawlor, DA; Manson, J; Nordestgaard, BG; Samani, NJ; Sandhu, M; Smeeth, L; Wensley, F; Anand, S; Bowden, J; Burgess, S; Casas, JP; Di Angelantonio, E; Engert, J; Gao, P; Shah, T; Smeeth, L; Thompson, SG; Verzilli, C; Walker, M; Whittaker, J; Hingorani, A; Danesh, J; (2010) Bayesian methods for meta-analysis of causal relationships estimated using genetic instrumental variables. Statistics in medicine, 29 (12). pp. 1298-1311. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.3843 Full text not available from this repository.

Dixon, PH; Wadsworth, CA; Chambers, J; Donnelly, J; Cooley, SM; Jarvis, S; Kubitz, R; Lammert, F; Marschall, HU; Glantz, A; +4 more... Khan, SA; Whittaker, J; Geary, M; Williamson, C; (2010) The Role of Common Genetic Variation around Six Candidate Loci for Susceptibility to Intrahepatic Cholestasis of Pregnancy. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/902 Full text not available from this repository.

Fararouei, Mohammad; Robertson, Claire; Whittaker, John; Sovio, Ulla; Ruokonen, Aimo; Pouta, Anneli; Hartikainen, Anna-Liisa; Jarvelin, Marjo-Riitta; Hyppönen, Elina; (2010) Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years. The British journal of nutrition, 104 (9). pp. 1363-1368. ISSN 0007-1145 DOI: https://doi.org/10.1017/S0007114510002175
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Morris, David L; Roberts, Amy L; Witherden, Abigail S; Tarzi, Ruth; Barros, Paula; Whittaker, John C; Cook, Terence H; Aitman, Timothy J; Vyse, Timothy J; (2010) Evidence for both copy number and allelic (NA1/NA2) risk at the FCGR3B locus in systemic lupus erythematosus. European journal of human genetics, 18 (9). pp. 1027-1031. ISSN 1018-4813 DOI: https://doi.org/10.1038/ejhg.2010.56 Full text not available from this repository.

Nonyane, BAS; Whittaker, JC; (2010) A variance components factor model for genetic association studies: a Bayesian analysis. Genetic epidemiology, 34 (6). pp. 529-536. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20503 Full text not available from this repository.

Shah, S; Drenos, F; Shah, T; Palmen, J; Sofat, R; Kumari, M; Pallas, J; MacFarlane, P; Whittaker, J; Talmud, P; +2 more... Humphries, S; Hingorani, A; (2010) Identification of Genes Associated with Qt Interval Using the 50k Cardio-Metabolic Snp Chip: Results from the Whitehall II Study. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/2938 Full text not available from this repository.

Shah, Tina; Newcombe, Paul; Smeeth, Liam; Addo, Juliet; Casas, Juan P; Whittaker, John; Miller, Michelle A; Tinworth, Lorna; Jeffery, Steve; Strazzullo, Pasquale; +2 more... Cappuccio, Francesco P; Hingorani, Aroon D; (2010) Ancestry as a determinant of mean population C-reactive protein values: implications for cardiovascular risk prediction. Circulation Cardiovascular genetics, 3 (5). pp. 436-444. ISSN 1942-325X DOI: https://doi.org/10.1161/CIRCGENETICS.110.957431 Full text not available from this repository.

Sofat, Reecha; Casas, Juan P; Kumari, Meena; Talmud, Philippa J; Ireland, Helen; Kivimaki, Mika; Marmot, Michael; Hughes, Alun D; Thom, Simon; Ebrahim, Shah; +5 more... Whittaker, John C; Smeeth, Liam; Lawlor, Debbie A; Humphries, Steve E; Hingorani, Aroon D; (2010) Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals. Atherosclerosis, 213 (1). pp. 184-190. ISSN 0021-9150 DOI: https://doi.org/10.1016/j.atherosclerosis.2010.07.021 Full text not available from this repository.

2009

Balchin, I; Whittaker, JC; Lamont, RF; Steer, PJ; (2009) The effect of exclusion of cases with unrecorded best estimate of gestational age on the estimates of preterm birth rate. BJOG, 116 (9). pp. 1218-1224. ISSN 1470-0328 DOI: https://doi.org/10.1111/j.1471-0528.2009.02184.x Full text not available from this repository.

Chapman, Juliet M; Onnie, Clive M; Prescott, Natalie J; Fisher, Sheila A; Mansfield, John C; Mathew, Christopher G; Lewis, Cathryn M; Verzilli, Claudio J; Whittaker, John C; (2009) Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease. American journal of human genetics, 84 (2). pp. 178-187. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2008.12.015 Full text not available from this repository.

Clarke, Mary C; Tanskanen, Antti; Huttunen, Matti; Whittaker, John C; Cannon, Mary; (2009) Evidence for an interaction between familial liability and prenatal exposure to infection in the causation of schizophrenia. The American journal of psychiatry, 166 (9). pp. 1025-1030. ISSN 0002-953X DOI: https://doi.org/10.1176/appi.ajp.2009.08010031 Full text not available from this repository.

Doudney, K; Grinham, J; Whittaker, J; Lynch, SA; Thompson, D; Moore, GE; Copp, AJ; Greene, NDE; Stanier, P; (2009) Evaluation of folate metabolism gene polymorphisms as risk factors for open and closed neural tube defects. American journal of medical genetics Part A, 149A (7). pp. 1585-1589. ISSN 1552-4825 DOI: https://doi.org/10.1002/ajmg.a.32937 Full text not available from this repository.

Khalique, Lalarukh; Ayhan, Ayse; Whittaker, John C; Singh, Naveena; Jacobs, Ian J; Gayther, Simon A; Ramus, Susan J; (2009) The clonal evolution of metastases from primary serous epithelial ovarian cancers. International journal of cancer Journal international du cancer, 124 (7). pp. 1579-1586. ISSN 0020-7136 DOI: https://doi.org/10.1002/ijc.24148 Full text not available from this repository.

Lunn, David J; Best, Nicky; Whittaker, John C; (2009) Generic reversible jump MCMC using graphical models. Statistics and computing, 19 (4). pp. 395-408. ISSN 0960-3174 DOI: https://doi.org/10.1007/s11222-008-9100-0 Full text not available from this repository.

Mead, Simon; Poulter, Mark; Uphill, James; Beck, John; Whitfield, Jerome; Webb, Thomas EF; Campbell, Tracy; Adamson, Gary; Deriziotis, Pelagia; Tabrizi, Sarah J; +5 more... Hummerich, Holger; Verzilli, Claudio; Alpers, Michael P; Whittaker, John C; Collinge, John; (2009) Genetic risk factors for variant Creutzfeldt-Jakob disease: a genome-wide association study. Lancet neurology, 8 (1). pp. 57-66. ISSN 1474-4422 DOI: https://doi.org/10.1016/S1474-4422(08)70265-5
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Mead, Simon; Whitfield, Jerome; Poulter, Mark; Shah, Paresh; Uphill, James; Campbell, Tracy; Al-Dujaily, Huda; Hummerich, Holger; Beck, Jon; Mein, Charles A; +4 more... Verzilli, Claudio; Whittaker, John; Alpers, Michael P; Collinge, John; (2009) A novel protective prion protein variant that colocalizes with kuru exposure. The New England journal of medicine, 361 (21). pp. 2056-2065. ISSN 0028-4793 DOI: https://doi.org/10.1056/NEJMoa0809716
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Newcombe, Paul J; Verzilli, Claudio; Casas, Juan P; Hingorani, Aroon D; Smeeth, Liam; Whittaker, John C; (2009) Multilocus Bayesian meta-analysis of gene-disease associations. American journal of human genetics, 84 (5). pp. 567-580. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2009.04.001 Full text not available from this repository.

Nonyane, Bareng AS; Nitsch, Dorothea; Whittaker, John C; Sofat, Reecha; Smeeth, Liam; Chakravarthy, Usha; Fletcher, Astrid E; (2009) An ecological correlation study of late age-related macular degeneration and the complement factor H Y402H polymorphism. Investigative ophthalmology & visual science, 51 (5). pp. 2393-2402. ISSN 0146-0404 DOI: https://doi.org/10.1167/iovs.09-4228 Full text not available from this repository.

Rao, Rohit; Tah, Vikas; Casas, Juan Pablo; Hingorani, Aroon; Whittaker, John; Smeeth, Liam; Sharma, Pankaj; (2009) Ischaemic stroke subtypes and their genetic basis: a comprehensive meta-analysis of small and large vessel stroke. European neurology, 61 (2). pp. 76-86. ISSN 0014-3022 DOI: https://doi.org/10.1159/000177939 Full text not available from this repository.

Rhodes, B; Hunnangkul, S; Morris, DL; Hsaio, L-C; Graham, DS Cunninghame; Nitsch, D; Whittaker, JC; Vyse, TJ; (2009) The heritability and genetics of complement C3 expression in UK SLE families. Genes and immunity, 10 (5). pp. 525-530. ISSN 1466-4879 DOI: https://doi.org/10.1038/gene.2009.23 Full text not available from this repository.

Shah, S; Drenos, F; Shah, T; Palmen, J; Verzilli, C; Sofat, R; Kumari, M; Kivamaki, M; Pallas, J; MacFarlane, P; +4 more... Whittaker, J; Talmud, PJ; Humphries, SE; Hingorani, AD; (2009) IDENTIFICATION OF GENES ASSOCIATED WITH QT INTERVAL USING THE 50K CARDIO-METABOLIC SNP CHIP: RESULTS FROM THE WHITEHALL II STUDY. [Conference or Workshop Item] https://doi.org/10.1016/j.atherosclerosis.2009.09.058 Full text not available from this repository.

Sovio, Ulla; Bennett, Amanda J; Millwood, Iona Y; Molitor, John; O'Reilly, Paul F; Timpson, Nicholas J; Kaakinen, Marika; Laitinen, Jaana; Haukka, Jari; Pillas, Demetris; +13 more... Tzoulaki, Ioanna; Molitor, Jassy; Hoggart, Clive; Coin, Lachlan JM; Whittaker, John; Pouta, Anneli; Hartikainen, Anna-Liisa; Freimer, Nelson B; Widen, Elisabeth; Peltonen, Leena; Elliott, Paul; McCarthy, Mark I; Jarvelin, Marjo-Riitta; (2009) Genetic determinants of height growth assessed longitudinally from infancy to adulthood in the northern Finland birth cohort 1966. PLoS genetics, 5 (3). e1000409-. ISSN 1553-7390 DOI: https://doi.org/10.1371/journal.pgen.1000409
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Talmud, Philippa J; Drenos, Fotios; Shah, Sonia; Shah, Tina; Palmen, Jutta; Verzilli, Claudio; Gaunt, Tom R; Pallas, Jacky; Lovering, Ruth; Li, Kawah; +29 more... Casas, Juan Pablo; Sofat, Reecha; Kumari, Meena; Rodriguez, Santiago; Johnson, Toby; Newhouse, Stephen J; Dominiczak, Anna; Samani, Nilesh J; Caulfield, Mark; Sever, Peter; Stanton, Alice; Shields, Denis C; Padmanabhan, Sandosh; Melander, Olle; Hastie, Claire; Delles, Christian; Ebrahim, Shah; Marmot, Michael G; Smith, George Davey; Lawlor, Debbie A; Munroe, Patricia B; Day, Ian N; Kivimaki, Mika; Whittaker, John; Humphries, Steve E; Hingorani, Aroon D; ASCOT investigators; NORDIL investigators; BRIGHT Consortium; (2009) Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. American journal of human genetics, 85 (5). pp. 628-642. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2009.10.014 Full text not available from this repository.

Webb, TEF; Whittaker, J; Collinge, J; Mead, S; (2009) Age of onset and death in inherited prion disease are heritable. American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4). pp. 496-501. ISSN 1552-4841 DOI: https://doi.org/10.1002/ajmg.b.30844 Full text not available from this repository.

2008

Balchin, Imelda; Whittaker, John C; Lamont, Ronald F; Steer, Philip J; (2008) Timing of planned cesarean delivery by racial group. Obstetrics and gynecology, 111 (3). pp. 659-666. ISSN 0029-7844 DOI: https://doi.org/10.1097/AOG.0b013e318163cd55 Full text not available from this repository.

Barton, Sheila J; Whittaker, John C; (2008) Review of factors that influence the abundance of ions produced in a tandem mass spectrometer and statistical methods for discovering these factors. Mass spectrometry reviews, 28 (1). pp. 177-187. ISSN 0277-7037 DOI: https://doi.org/10.1002/mas.20188 Full text not available from this repository.

Chadeau-Hyam, Marc; Hoggart, Clive J; O'Reilly, Paul F; Whittaker, John C; De Iorio, Maria; Balding, David J; (2008) Fregene: simulation of realistic sequence-level data in populations and ascertained samples. BMC bioinformatics, 9 (1). 364-. ISSN 1471-2105 DOI: https://doi.org/10.1186/1471-2105-9-364
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Chapman, JM; Onnie, C; Prescott, N; Fisher, S; Lewis, C; Mathew, C; Verzilli, CJ; Whittaker, JC; (2008) Searching for genotype-phenotype structure: Trying to understand Crohn's disease. Annals of human genetics, 72. p. 688. ISSN 0003-4800 https://researchonline.lshtm.ac.uk/id/eprint/7101 Full text not available from this repository.

Chapman, Juliet; Whittaker, John; (2008) Analysis of multiple SNPs in a candidate gene or region. Genetic epidemiology, 32 (6). pp. 560-566. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20330 Full text not available from this repository.

Cunninghame Graham, Deborah S; Graham, Robert R; Manku, Harinder; Wong, Andrew K; Whittaker, John C; Gaffney, Patrick M; Moser, Kathy L; Rioux, John D; Altshuler, David; Behrens, Timothy W; +1 more... Vyse, Timothy J; (2008) Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. Nature genetics, 40 (1). pp. 83-89. ISSN 1061-4036 DOI: https://doi.org/10.1038/ng.2007.47 Full text not available from this repository.

Elmasry, K; Ramus, S; Whittaker, J; Luo, Z; Gammerman, A; Lu, K; Ayhan, A; Singh, N; McGluggage, G; Jacobs, I; +1 more... Gayther, S; (2008) Genetic diagnosis and clinical outcome in patients with synchronous ovarian and endometrial cancer. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/8017 Full text not available from this repository.

Hoggart, Clive J; Clark, Taane G; De Iorio, Maria; Whittaker, John C; Balding, David J; (2008) Genome-wide significance for dense SNP and resequencing data. Genetic epidemiology, 32 (2). pp. 179-185. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20292 Full text not available from this repository.

Hoggart, Clive J; Whittaker, John C; De Iorio, Maria; Balding, David J; (2008) Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies. PLoS genetics, 4 (7). e1000130-. ISSN 1553-7390 DOI: https://doi.org/10.1371/journal.pgen.1000130
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Hunnangkul, Saowalak; Nitsch, Dorothea; Rhodes, Benjamin; Chadha, Sapna; Roberton, Cheri A; Pessôa-Lopes, Pedro; Norsworthy, Peter J; Fernando, Michelle MA; Charles, Peter; Mackworth-Young, Charles; +3 more... Isenberg, David A; Whittaker, John C; Vyse, Timothy J; (2008) Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus. Arthritis and rheumatism, 58 (4). pp. 1116-1124. ISSN 0004-3591 DOI: https://doi.org/10.1002/art.23400 Full text not available from this repository.

Newcombe, PJ; Verzilli, C; Pablo-Casas, J; Whittaker, J; (2008) Meta-analysis of gene/disease association studies. Annals of human genetics, 72. p. 689. ISSN 0003-4800 https://researchonline.lshtm.ac.uk/id/eprint/7102 Full text not available from this repository.

Peck, George; Smeeth, Liam; Whittaker, John; Casas, Juan Pablo; Hingorani, Aroon; Sharma, Pankaj; (2008) The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults. PloS one, 3 (11). e3691-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0003691
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Ramus, Susan J; Elmasry, Karim; Luo, Zhiyuan; Gammerman, Alex; Lu, Karen; Ayhan, Ayse; Singh, Naveena; McCluggage, W Glenn; Jacobs, Ian J; Whittaker, John C; +1 more... Gayther, Simon A; (2008) Predicting clinical outcome in patients diagnosed with synchronous ovarian and endometrial cancer. Clinical cancer research, 14 (18). pp. 5840-5848. ISSN 1078-0432 DOI: https://doi.org/10.1158/1078-0432.CCR-08-0373 Full text not available from this repository.

Rhodes, B; Meek, J; Whittaker, JC; Vyse, TJ; (2008) Quantification of the genetic component of basal C-reactive protein expression in SLE nuclear families. Annals of human genetics, 72 (Pt 5). pp. 611-620. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1469-1809.2008.00444.x Full text not available from this repository.

Rhodes, B; Meek, J; Whittaker, JC; Vyse, TJ; (2008) Quantification of the genetic component of basal C-reactive protein expression in SLE nuclear families. Annals of human genetics, 72. pp. 611-620. ISSN 0003-4800 https://researchonline.lshtm.ac.uk/id/eprint/7103 Full text not available from this repository.

Rhodes, Benjamin; Morris, David L; Subrahmanyan, Lakshman; Aubin, Cristin; de Leon, Carlos F Mendes; Kelly, Jeremiah F; Evans, Dennis A; Whittaker, John C; Oksenberg, Jorge R; De Jager, Philip L; +1 more... Vyse, Tim J; (2008) Fine-mapping the genetic basis of CRP regulation in African Americans: a Bayesian approach. Human genetics, 123 (6). pp. 633-642. ISSN 0340-6717 DOI: https://doi.org/10.1007/s00439-008-0517-5 Full text not available from this repository.

Verzilli, Claudio; Shah, Tina; Casas, Juan P; Chapman, Juliet; Sandhu, Manjinder; Debenham, Sally L; Boekholdt, Matthijs S; Khaw, Kay Tee; Wareham, Nicholas J; Judson, Richard; +10 more... Benjamin, Emelia J; Kathiresan, Sekar; Larson, Martin G; Rong, Jian; Sofat, Reecha; Humphries, Steve E; Smeeth, Liam; Cavalleri, Gianpiero; Whittaker, John C; Hingorani, Aroon D; (2008) Bayesian meta-analysis of genetic association studies with different sets of markers. American journal of human genetics, 82 (4). pp. 859-872. ISSN 0002-9297 DOI: https://doi.org/10.1016/j.ajhg.2008.01.016 Full text not available from this repository.

Webb, TE; Whittaker, J; Collinge, J; Mead, S; (2008) Age of onset and death in inherited prion disease are heritable. American journal of medical genetics Part B, Neuropsychiatric genetics, 150B (4). pp. 496-501. ISSN 1552-4841 DOI: https://doi.org/10.1002/ajmg.b.30844 Full text not available from this repository.

2007

Apostolidou, S; Abu-Amero, S; O'Donoghue, K; Frost, J; Olafsdottir, O; Chavele, KM; Whittaker, JC; Loughna, P; Stanier, P; Moore, GE; (2007) Elevated placental expression of the imprinted PHLDA2 gene is associated with low birth weight. Journal of molecular medicine (Berlin, Germany), 85 (4). pp. 379-387. ISSN 0946-2716 DOI: https://doi.org/10.1007/s00109-006-0131-8 Full text not available from this repository.

Baksh, M Fazil; Balding, David J; Vyse, Timothy J; Whittaker, John C; (2007) Family-based association analysis with ordered categorical phenotypes, covariates and interactions. Genetic epidemiology, 31 (1). pp. 1-8. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20183 Full text not available from this repository.

Balchin, Imelda; Whittaker, John C; Patel, Roshni R; Lamont, Ronald F; Steer, Philip J; (2007) Racial variation in the association between gestational age and perinatal mortality: prospective study. BMJ (Clinical research ed), 334 (7598). 833-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.39132.482025.80
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Barton, Sheila J; Richardson, Sylvia; Perkins, David N; Bellahn, Inga; Bryant, Trevor N; Whittaker, John C; (2007) Using statistical models to identify factors that have a role in defining the abundance of ions produced by tandem MS. Analytical chemistry, 79 (15). pp. 5601-5607. ISSN 0003-2700 DOI: https://doi.org/10.1021/ac0700272 Full text not available from this repository.

Drenos, F; Whittaker, JC; Humphries, SE; (2007) The use of meta-analysis risk estimates for candidate genes in combination to predict coronary heart disease risk. Annals of human genetics, 71 (Pt 5). pp. 611-619. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1469-1809.2007.00359.x Full text not available from this repository.

Hoggart, C; de Iorio, M; Whittaker, J; Balding, D; (2007) Bayesian shrinkage priors for detecting multiple causal variants from genome-wide association studies. Annals of human genetics, 71. p. 557. ISSN 0003-4800 https://researchonline.lshtm.ac.uk/id/eprint/8558 Full text not available from this repository.

Hoggart, CJ; de Iorio, M; Whittaker, JC; Balding, DJ; (2007) Simultaneous analysis of genome-wide SNP data. Genetic epidemiology, 31 (6). p. 609. ISSN 0741-0395 https://researchonline.lshtm.ac.uk/id/eprint/8559 Full text not available from this repository.

Hoggart, Clive J; Chadeau-Hyam, Marc; Clark, Taane G; Lampariello, Riccardo; Whittaker, John C; De Iorio, Maria; Balding, David J; (2007) Sequence-level population simulations over large genomic regions. Genetics, 177 (3). pp. 1725-1731. ISSN 0016-6731 DOI: https://doi.org/10.1534/genetics.106.069088 Full text not available from this repository.

Sharma, P; Whittaker, J; Casas, JP; Hingorani, AD; Ariyaratnam, R; (2007) Genetics of ischaemic stroke in ethnic minorities. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/9688 Full text not available from this repository.

Van Mil, Saskia WC; Milona, Alexandra; Dixon, Peter H; Mullenbach, Roman; Geenes, Victoria L; Chambers, Jenny; Shevchuk, Vasylyna; Moore, Gudrun E; Lammert, Frank; Glantz, Anna G; +5 more... Mattsson, Lars-Ake; Whittaker, John; Parker, Malcolm G; White, Roger; Williamson, Catherine; (2007) Functional variants of the central bile acid sensor FXR identified in intrahepatic cholestasis of pregnancy. Gastroenterology, 133 (2). pp. 507-516. ISSN 0016-5085 DOI: https://doi.org/10.1053/j.gastro.2007.05.015 Full text not available from this repository.

Verzilli, C; Chapman, J; Hingorani, A; Pablo-Casas, J; Shah, T; Smeeth, L; Whittaker, J; (2007) Bayesian meta analysis of genetic association studies with different sets of markers. Annals of human genetics, 71. pp. 552-553. ISSN 0003-4800 https://researchonline.lshtm.ac.uk/id/eprint/8490 Full text not available from this repository.

Whittaker, JC; Chapman, J; (2007) Analysis of multiple SNPs in a candidate gene or region. Genetic epidemiology, 31 (6). p. 650. ISSN 0741-0395 https://researchonline.lshtm.ac.uk/id/eprint/8560 Full text not available from this repository.

2006

Apostolidou, S; Abu-Amero, S; O'Donoghue, K; Olafsdottir, O; Chavele, KM; Frost, J; Whittaker, JC; Loughna, P; Stanier, P; Moore, GE; (2006) Elevated maternal expression of the imprinted PHLDA2 gene is associated with low birth weight. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/9687 Full text not available from this repository.

Baksh, MF; Balding, DJ; Vyse, TJ; Whittaker, JC; (2006) A likelihood ratio approach to family-based association studies with covariates. Annals of human genetics, 70 (Pt 1). pp. 131-139. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1529-8817.2005.00189.x Full text not available from this repository.

Cunninghame Graham, DS; Wong, AK; McHugh, NJ; Whittaker, JC; Vyse, Timothy J; (2006) Evidence for unique association signals in SLE at the CD28-CTLA4-ICOS locus in a family-based study. Human molecular genetics, 15 (21). pp. 3195-3205. ISSN 0964-6906 DOI: https://doi.org/10.1093/hmg/ddl395 Full text not available from this repository.

Fletcher, Olivia; Johnson, Nichola; Palles, Claire; dos Santos Silva, Isabel; McCormack, Valerie; Whittaker, John; Ashworth, Alan; Peto, Julian; (2006) Inconsistent association between the STK15 F31I genetic polymorphism and breast cancer risk. Journal of the National Cancer Institute, 98 (14). pp. 1014-1018. ISSN 0027-8874 DOI: https://doi.org/10.1093/jnci/djj268 Full text not available from this repository.

Lunn, David J; Whittaker, John C; Best, Nicky; (2006) A Bayesian toolkit for genetic association studies. Genetic epidemiology, 30 (3). pp. 231-247. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20140 Full text not available from this repository.

Rohrmann, Sabine; Linseisen, Jakob; Boshuizen, Hendriek C; Whittaker, John; Agudo, Antonio; Vineis, Paolo; Boffetta, Paolo; Jensen, Majken K; Olsen, Anja; Overvad, Kim; +34 more... Tjønneland, Anne; Boutron-Ruault, Marie-Christine; Clavel-Chapelon, Françoise; Bergmann, Manuela M; Boeing, Heiner; Allen, Naomi; Key, Tim; Bingham, Sheila; Khaw, Kay-Tee; Kyriazi, Georgia; Soukara, Stavroula; Trichopoulou, Antonia; Panico, Salvatore; Palli, Domenico; Sieri, Sabina; Tumino, Rosario; Peeters, Petra HM; Bueno-de-Mesquita, H Bas; Büchner, Frederike L; Gram, Inger Torhild; Lund, Eiliv; Ardanaz, Eva; Chirlaque, María-Dolores; Dorronsoro, Miren; Pérez, Maria-José Sánchez; Quirós, Jose R; Berglund, Göran; Janzon, Lars; Rasmuson, Torgny; Weinehall, Lars; Ferrari, Pietro; Jenab, Mazda; Norat, Teresa; Riboli, Elio; (2006) Ethanol intake and risk of lung cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). American journal of epidemiology, 164 (11). pp. 1103-1114. ISSN 0002-9262 DOI: https://doi.org/10.1093/aje/kwj326 Full text not available from this repository.

Underwood, SL; Christoforou, A; Thomson, PA; Wray, NR; Tenesa, A; Whittaker, J; Adams, RA; Le Hellard, S; Morris, SW; Blackwood, DHR; +3 more... Muir, WJ; Porteous, DJ; Evans, KL; (2006) Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia. Molecular psychiatry, 11 (4). pp. 384-394. ISSN 1359-4184 DOI: https://doi.org/10.1038/sj.mp.4001786 Full text not available from this repository.

Verzilli, Claudio J; Stallard, Nigel; Whittaker, John C; (2006) Bayesian graphical models for genomewide association studies. American journal of human genetics, 79 (1). pp. 100-112. ISSN 0002-9297 DOI: https://doi.org/10.1086/505313 Full text not available from this repository.

Waldron, ERB; Whittaker, JC; Balding, DJ; (2006) Fine mapping of disease genes via haplotype clustering. Genetic epidemiology, 30 (2). pp. 170-179. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20134 Full text not available from this repository.

2005

Christoforou, A; Underwood, SL; Hellard, SL; Wray, NR; Morris, SW; Tenesa, A; Thomson, PA; Whittaker, J; Blackwood, DH; Muir, WJ; +2 more... Porteous, DJ; Evans, KL; (2005) Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia. American journal of medical genetics Part B, Neuropsychiatric genetics, 138B (1). p. 47. ISSN 1552-4841 https://researchonline.lshtm.ac.uk/id/eprint/12455 Full text not available from this repository.

Hubner, Norbert; Wallace, Caroline A; Zimdahl, Heike; Petretto, Enrico; Schulz, Herbert; Maciver, Fiona; Mueller, Michael; Hummel, Oliver; Monti, Jan; Zidek, Vaclav; +12 more... Musilova, Alena; Kren, Vladimir; Causton, Helen; Game, Laurence; Born, Gabriele; Schmidt, Sabine; Müller, Anita; Cook, Stuart A; Kurtz, Theodore W; Whittaker, John; Pravenec, Michal; Aitman, Timothy J; (2005) Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease. Nature genetics, 37 (3). pp. 243-253. ISSN 1061-4036 DOI: https://doi.org/10.1038/ng1522 Full text not available from this repository.

Kelly, Patrick J; Stallard, Nigel; Whittaker, John C; (2005) Statistical design and analysis of pharmacogenetic trials. Statistics in medicine, 24 (10). pp. 1495-1508. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.2052 Full text not available from this repository.

Pardi, F; Lewis, CM; Whittaker, JC; (2005) SNP selection for association studies: maximizing power across SNP choice and study size. Annals of human genetics, 69 (Pt 6). pp. 733-746. ISSN 0003-4800 DOI: https://doi.org/10.1111/j.1529-8817.2005.00202.x Full text not available from this repository.

Pardi, Fabio; Sibly, Richard M; Wilkinson, MJ; Whittaker, John C; (2005) On the structural differences between markers and genomic AC microsatellites. Journal of molecular evolution, 60 (5). pp. 688-693. ISSN 0022-2844 DOI: https://doi.org/10.1007/s00239-004-0274-6 Full text not available from this repository.

Russell, AI; Cunninghame Graham, DS; Chadha, S; Roberton, C; Fernandez-Hart, T; Griffiths, B; D'Cruz, D; Nitsch, D; Whittaker, JC; Vyse, TJ; (2005) No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE. Genes and immunity, 6 (5). pp. 422-429. ISSN 1466-4879 DOI: https://doi.org/10.1038/sj.gene.6364222 Full text not available from this repository.

Verzilli, Claudio J; Stallard, Nigel; Whittaker, John C; (2005) Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions. Genetic epidemiology, 28 (4). pp. 313-325. ISSN 0741-0395 DOI: https://doi.org/10.1002/gepi.20072 Full text not available from this repository.

Verzilli, Claudio J; Whittaker, John C; Stallard, Nigel; Chasman, Daniel; (2005) A hierarchical Bayesian model for predicting the functional consequences of amino-acid polymorphisms. Applied statistics, 54 (1). pp. 191-206. ISSN 0035-9254 DOI: https://doi.org/10.1111/j.1467-9876.2005.00478.x Full text not available from this repository.

Waldron, ERB; Whittaker, JC; Balding, DJ; (2005) A spatial clustering approach to fine-mapping of disease genes. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/6482 Full text not available from this repository.

2004

Balchin, Imelda; Whittaker, John C; Steer, Philip J; Lamont, Ronald F; (2004) Are reported preterm birth rates reliable? An analysis of interhospital differences in the calculation of the weeks of gestation at delivery and preterm birth rate. BJOG, 111 (2). pp. 160-163. ISSN 1470-0328 DOI: https://doi.org/10.1046/j.1471-0528.2003.00026.x Full text not available from this repository.

Morris, AP; Whittaker, JC; Balding, DJ; (2004) Little loss of information due to unknown phase for fine-scale linkage-disequilibrium mapping with single-nucleotide-polymorphism genotype data. American journal of human genetics, 74 (5). pp. 945-953. ISSN 0002-9297 DOI: https://doi.org/10.1086/420773 Full text not available from this repository.

Russell, Andrew I; Cunninghame Graham, Deborah S; Shepherd, Christopher; Roberton, Cheri A; Whittaker, John; Meeks, John; Powell, Richard J; Isenberg, David A; Walport, Mark J; Vyse, Timothy J; (2004) Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus. Human molecular genetics, 13 (1). pp. 137-147. ISSN 0964-6906 DOI: https://doi.org/10.1093/hmg/ddh021 Full text not available from this repository.

2003

Byng, MC; Whittaker, JC; Cuthbert, AP; Mathew, CG; Lewis, CM; (2003) SNP subset selection for genetic association studies. Annals of human genetics, 67 (Pt 6). pp. 543-556. ISSN 0003-4800 DOI: https://doi.org/10.1046/j.1529-8817.2003.00055.x Full text not available from this repository.

Byng, Martyn C; Fisher, Sheila A; Lewis, Cathryn M; Whittaker, John C; Framingham Heart Study; (2003) Variance components linkage analysis for adjusted systolic blood pressure in the Framingham Heart Study. BMC genetics, 4 Supp (Suppl). S4-. ISSN 1471-2156 DOI: https://doi.org/10.1186/1471-2156-4-S1-S4
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Denham, Michael C; Whittaker, John C; (2003) A Bayesian approach to disease gene location using allelic association. Biostatistics (Oxford, England), 4 (3). pp. 399-409. ISSN 1465-4644 DOI: https://doi.org/10.1093/biostatistics/4.3.399 Full text not available from this repository.

Morris, Andrew P; Whittaker, John C; Xu, Chun-Fang; Hosking, Louise K; Balding, David J; (2003) Multipoint linkage-disequilibrium mapping narrows location interval and identifies mutation heterogeneity. Proceedings of the National Academy of Sciences of the United States of America, 100 (23). pp. 13442-13446. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.2235031100 Full text not available from this repository.

Sibly, Richard M; Meade, Andrew; Boxall, Nicola; Wilkinson, Michael J; Corne, Dave W; Whittaker, John C; (2003) The structure of interrupted human AC microsatellites. Molecular biology and evolution, 20 (3). pp. 453-459. ISSN 0737-4038 DOI: https://doi.org/10.1093/molbev/msg056 Full text not available from this repository.

Whittaker, John C; Gharani, Neda; Hindmarsh, Peter; McCarthy, Mark I; (2003) Estimation and testing of parent-of-origin effects for quantitative traits. American journal of human genetics, 72 (4). pp. 1035-1039. ISSN 0002-9297 DOI: https://doi.org/10.1086/374382 Full text not available from this repository.

Whittaker, John C; Harbord, Roger M; Boxall, Nicola; Mackay, Ian; Dawson, Gary; Sibly, Richard M; (2003) Likelihood-based estimation of microsatellite mutation rates. Genetics, 164 (2). pp. 781-787. ISSN 0016-6731 https://researchonline.lshtm.ac.uk/id/eprint/13639 Full text not available from this repository.

2002

Lange, C; Whittaker, JC; (2002) Generalised estimating equations: a hybrid approach for mean parameters in multivariate regression models. Statistical Modelling, 2. pp. 163-181. ISSN 1477-0342 https://researchonline.lshtm.ac.uk/id/eprint/13386 Full text not available from this repository.

Lange, C; Whittaker, JC; (2002) Model selection for quasi-likelihood: a new approach. In: Gregori, D; Cameci, G; Friedl, H; Ferligoi, A; Wedlin, A, (eds.) Correlated Data Modeling. Economia/Ricerche, Collana. https://researchonline.lshtm.ac.uk/id/eprint/13385 Full text not available from this repository.

Morris, AP; Whittaker, JC; Balding, DJ; (2002) Fine-scale mapping of disease loci via shattered coalescent modeling of genealogies. American journal of human genetics, 70 (3). pp. 686-707. ISSN 0002-9297 DOI: https://doi.org/10.1086/339271 Full text not available from this repository.

2001

Lange, C; Whittaker, JC; (2001) Mapping quantitative trait Loci using generalized estimating equations. Genetics, 159 (3). pp. 1325-1337. ISSN 0016-6731 https://researchonline.lshtm.ac.uk/id/eprint/13633 Full text not available from this repository.

Lange, C; Whittaker, JC; (2001) On prediction of genetic values in marker-assisted selection. Genetics, 159 (3). pp. 1375-1381. ISSN 0016-6731 https://researchonline.lshtm.ac.uk/id/eprint/13634 Full text not available from this repository.

Lewis, CM; Pinêl, T; Whittaker, JC; Handyside, AH; (2001) Controlling misdiagnosis errors in preimplantation genetic diagnosis: a comprehensive model encompassing extrinsic and intrinsic sources of error. Human reproduction (Oxford, England), 16 (1). pp. 43-50. ISSN 0268-1161 DOI: https://doi.org/10.1093/humrep/16.1.43 Full text not available from this repository.

Sibly, RM; Whittaker, JC; Talbot, M; (2001) A maximum-likelihood approach to fitting equilibrium models of microsatellite evolution. Molecular biology and evolution, 18 (3). pp. 413-417. ISSN 0737-4038 DOI: https://doi.org/10.1093/oxfordjournals.molbev.a003817 Full text not available from this repository.

Whittaker, JC; (2001) Marker assisted selection and introgression. In: Balding, DJ; Bishop, M; Cannings, C, (eds.) Handbook of Statistical Genetics. Wiley. https://researchonline.lshtm.ac.uk/id/eprint/13387 Full text not available from this repository.

Whittaker, JC; Morris, AP; (2001) Family-based tests of association and/or linkage. Annals of human genetics, 65 (Pt 5). pp. 407-419. ISSN 0003-4800 DOI: https://doi.org/10.1017/S0003480001008818 Full text not available from this repository.

This list was generated on Fri Jul 3 06:24:43 2020 BST.