Abu-Omar, Yasir; Thorpe, Benjamin S; Freeman, Carol; Mills, Christine; Stoneman, Victoria EA; Gopalan, Deepa; Rana, Bushra; Spyt, Tomasz J; Sharples, Linda D; Nashef, Samer AM; (2017) Recovery of Left Atrial Contractile Function After Maze Surgery in Persistent Longstanding Atrial Fibrillation. Journal of the American College of Cardiology, 70 (18). pp. 2309-2311. ISSN 0735-1097 DOI: https://doi.org/10.1016/j.jacc.2017.08.073

Barr, Andrew J; Dube, Bright; Hensor, Elizabeth MA; Kingsbury, Sarah R; Peat, George; Bowes, Mike A; Sharples, Linda D; Conaghan, Philip G; (2016) The relationship between three-dimensional knee MRI bone shape and total knee replacement-a case control study: data from the Osteoarthritis Initiative. Rheumatology (Oxford, England), 55 (9). pp. 1585-1593. ISSN 1462-0324 DOI: https://doi.org/10.1093/rheumatology/kew191

Benaglia, Tatiana; Jackson, Christopher H; Sharples, Linda D; (2014) Survival extrapolation in the presence of cause specific hazards. Statistics in medicine, 34 (5). pp. 796-811. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.6375

Blagden, SP; Charman, SC; Sharples, LD; Magee, LRA; Gilligan, D; (2003) Performance status score: do patients and their oncologists agree? British journal of cancer, 89 (6). pp. 1022-1027. ISSN 0007-0920 DOI: https://doi.org/10.1038/sj.bjc.6601231

Blake, Helen A; Sharples, Linda D; Boyle, Jemma M; Kuryba, Angela; Moonesinghe, Suneetha R; Murray, Dave; Hill, James; Fearnhead, Nicola S; van der Meulen, Jan H; Walker, Kate; (2024) Improving risk models for patients having emergency bowel cancer surgery using linked electronic health records: a national cohort study. International journal of surgery, 110 (3). pp. 1564-1576. ISSN 1743-9191 DOI: https://doi.org/10.1097/JS9.0000000000000966

Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate; (2021) Probabilistic linkage without personal information successfully linked national clinical datasets. Journal of clinical epidemiology, 136. pp. 136-145. ISSN 0895-4356 DOI: https://doi.org/10.1016/j.jclinepi.2021.04.015

Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate; (2022) Linkage of multiple electronic health record datasets using a 'spine linkage' approach compared with all 'pairwise linkages'. International Journal of Epidemiology, 52 (1). pp. 214-226. ISSN 0300-5771 DOI: https://doi.org/10.1093/ije/dyac130

Blencowe, Natalie S; Brown, Julia M; Cook, Jonathan A; Metcalfe, Chris; Morton, Dion G; Nicholl, Jon; Sharples, Linda D; Treweek, Shaun; Blazeby, Jane M; Members of the MRC Hub for Trials Methodology Research Network W; (2015) Interventions in randomised controlled trials in surgery: issues to consider during trial design. Trials, 16 (1). 392-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-015-0918-4

Bojke, Laura; Soares, Marta O; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Chris; Jankovic, Dina; Morton, Alec; Sharples, Linda D; Taylor, Andrea; (2021) Reference Case Methods for Expert Elicitation in Health Care Decision Making. Medical decision making, 42 (2). pp. 182-193. ISSN 0272-989X DOI: https://doi.org/10.1177/0272989X211028236

Bojke, Laura; Soares, Marta; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Christopher; Jankovic, Dina; Morton, Alec; Sharples, Linda; Taylor, Andrea; (2021) Developing a reference protocol for structured expert elicitation in health-care decision-making: a mixed-methods study. Health technology assessment, 25 (37). pp. 1-124. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta25370

Bowman, SJ; Everett, CC; O'Dwyer, JL; Emery, P; Pitzalis, C; Ng, WF; Pease, CT; Price, EJ; Sutcliffe, N; St Gendi, N; +13 more... Hall, FC; Ruddock, SP; Fernandez, C; Reynolds, C; Hulme, CT; Davies, KA; Edwards, CJ; Lanyon, PC; Moots, RJ; Roussou, E; Giles, IP; Sharples, LD; Bombardieri, M; (2017) Randomized Controlled Trial of Rituximab and cost-effectiveness analysis in treating fatigue and oral dryness in primary Sjogren's Syndrome. Arthritis & rheumatology (Hoboken, NJ). ISSN 2326-5191 DOI: https://doi.org/10.1002/art.40093

Brown, Sarah; Collier, Howard; Askew, L; Gilberts, Rachel; Sharples, Linda; Nixon, Jane; McGinnis, Elizabeth; Backhouse, M; Game, F; Faulks, F; +4 more... Ransom, Myka; Everett, Colin; Nelson, A; Russell, David; (2024) Diabetic Foot Ulcer Photography Study: Study Within a Trial to assess the reliability of 2D photography for the assessment of ulcer healing in patients with Diabetes-related Foot Ulcers – Protocol Paper. BMJ open. ISSN 2044-6055 https://researchonline.lshtm.ac.uk/id/eprint/4674611 (In Press) Item availability may be restricted.

Brown, Sarah; Nixon, Jane; Ransom, Myka; Gilberts, Rachael; Dewhirst, Nikki; McGinnis, Elizabeth; Longo, Roberta; Game, Frances; Bojke, Chris; Chadwick, Paul; +12 more... Chandrasekar, Akila; Chetter, Ian; Collier, Howard; Fernandez, Catherine; Homer-Vanniasinkam, Shervanthi; Jude, Edward; Leigh, Richard; Lomas, Richard; Vowden, Peter; Wason, James; Sharples, Linda; Russell, David; (2020) Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial. BMJ open, 10 (4). e035947-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2019-035947

Charman, Susan C; Sharples, Linda D; McNeil, Keith D; Wallwork, John; (2002) Assessment of survival benefit after lung transplantation by patient diagnosis. The Journal of heart and lung transplantation, 21 (2). pp. 226-232. ISSN 1053-2498 DOI: https://doi.org/10.1016/s1053-2498(01)00352-7 Full text not available from this repository.

Clayton, Gemma L; Smith, Isabelle L; Higgins, Julian PT; Mihaylova, Borislava; Thorpe, Benjamin; Cicero, Robert; Lokuge, Kusal; Forman, Julia R; Tierney, Jayne F; White, Ian R; +2 more... Sharples, Linda D; Jones, Hayley E; (2017) The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials. Trials, 18 (1). 219-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-017-1955-y

Cowling, Thomas E; Bellot, Alexis; Boyle, Jemma; Walker, Kate; Kuryba, Angela; Galbraith, Sarah; Aggarwal, Ajay; Braun, Michael; Sharples, Linda D; van der Meulen, Jan; (2020) One-year mortality of colorectal cancer patients: development and validation of a prediction model using linked national electronic data. British Journal of Cancer, 123 (10). pp. 1474-1480. ISSN 0007-0920 DOI: https://doi.org/10.1038/s41416-020-01034-w

Cowling, Thomas E; Cromwell, David A; Bellot, Alexis; Sharples, Linda D; van der Meulen, Jan; (2021) Logistic regression and machine learning predicted patient mortality from large sets of diagnosis codes comparably. Journal of Clinical Epidemiology, 133. pp. 43-52. ISSN 0895-4356 DOI: https://doi.org/10.1016/j.jclinepi.2020.12.018

Cowling, Thomas E; Cromwell, David A; Sharples, Linda D; van der Meulen, Jan; (2020) A novel approach selected small sets of diagnosis codes with high prediction performance in large healthcare datasets. Journal of Clinical Epidemiology, 128. pp. 20-28. ISSN 0895-4356 DOI: https://doi.org/10.1016/j.jclinepi.2020.08.001

Demiris, Nikolaos; Lunn, David; Sharples, Linda D; (2011) Survival extrapolation using the poly-Weibull model. Statistical methods in medical research, 24 (2). pp. 287-301. ISSN 0962-2802 DOI: https://doi.org/10.1177/0962280211419645

Dobson, Laura E; Fairbairn, Timothy A; Musa, Tarique A; Uddin, Akhlaque; Mundie, Cheryl A; Swoboda, Peter P; Ripley, David P; McDiarmid, Adam K; Erhayiem, Bara; Garg, Pankaj; +5 more... Malkin, Christopher J; Blackman, Daniel J; Sharples, Linda D; Plein, Sven; Greenwood, John P; (2016) Sex-related differences in left ventricular remodeling in severe aortic stenosis and reverse remodeling after aortic valve replacement: A cardiovascular magnetic resonance study. American heart journal, 175. pp. 101-111. ISSN 0002-8703 DOI: https://doi.org/10.1016/j.ahj.2016.02.010

Dyer, MT; Goldsmith, KA; Khan, SN; Sharples, LD; Freeman, C; Hardy, I; Buxton, MJ; Schofield, PM; (2008) Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial. TRIALS, 9 (1). 40-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-9-40

Edgar, K; Jackson, D; Rhodes, K; Duffy, T; Burman, C-F; Sharples, LD; (2021) Frequentist rules for regulatory approval of subgroups in phase III trials: A fresh look at an old problem. Statistical Methods in Medical Research, 30 (7). pp. 1725-1743. ISSN 0962-2802 DOI: https://doi.org/10.1177/09622802211017574

Edgar, Kate; Roberts, Ian; Sharples, Linda; (2021) Including random centre effects in design, analysis and presentation of multi-centre trials. Trials, 22 (1). 357-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-021-05266-w

Everett, Colin C; Fox, Keith Aa; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah D; Carruthers, Kathryn; Hemingway, Harry; Yan, Andrew T; Goodman, Shaun G; +3 more... Brieger, David; Chew, Derek P; Gale, Chris P; (2019) Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial. BMJ open, 9 (9). e032165-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2019-032165

Everett, Colin C; Reynolds, Catherine; Fernandez, Catherine; Stocken, Deborah D; Sharples, Linda D; Sathyapalan, Thozhukat; Heller, Simon; Storey, Robert F; Ajjan, Ramzi A; (2020) Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. DIABETES & VASCULAR DISEASE RESEARCH, 17 (5). 1479164120957934-. ISSN 1479-1641 DOI: https://doi.org/10.1177/1479164120957934

Fisher, Benjamin A; Everett, Colin C; Rout, John; O'Dwyer, John L; Emery, Paul; Pitzalis, Costantino; Ng, Wan-Fai; Carr, Andrew; Pease, Colin T; Price, Elizabeth J; +17 more... Sutcliffe, Nurhan; Makdissi, Jimmy; Tappuni, Anwar R; Gendi, Nagui ST; Hall, Frances C; Ruddock, Sharon P; Fernandez, Catherine; Hulme, Claire T; Davies, Kevin A; Edwards, Christopher John; Lanyon, Peter C; Moots, Robert J; Roussou, Euthalia; Richards, Andrea; Sharples, Linda D; Bombardieri, Michele; Bowman, Simon J; (2017) Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. Annals of the rheumatic diseases, 77 (3). pp. 412-416. ISSN 0003-4967 DOI: https://doi.org/10.1136/annrheumdis-2017-212268

Gale, Chris P; Stocken, Deborah D; Aktaa, Suleman; Reynolds, Catherine; Gilberts, Rachael; Brieger, David; Carruthers, Kathryn; Chew, Derek P; Goodman, Shaun G; Fernandez, Catherine; +3 more... Sharples, Linda D; Yan, Andrew T; Fox, Keith; (2023) Effectiveness of GRACE risk score in patients admitted to hospital with non-ST elevation acute coronary syndrome (UKGRIS): parallel group cluster randomised controlled trial. BMJ, 381. e073843-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj-2022-073843

Gale, Chris; Stocken, Deborah; Aktaa, Suleman; Reynolds, Catherine; Gilberts, Rachael; Brieger, David; Carruthers, Kathryn; Chew, Derek; Goodman, Shaun; Fernandez, Catherine; +3 more... Sharples, Linda; Yan, Andrew; Fox, Keith; (2023) Effectiveness of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome (UKGRIS): a parallel-group cluster-randomised registry-based controlled trial. BMJ, 381. e07384. ISSN 1468-5833 DOI: https://doi.org/10.1136/bmj-2022-073843

Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda; (2020) Evaluating the effect of healthcare providers on the clinical path of heart failure patients through a semi-Markov, multi-state model. BMC Health Services Research, 20 (1). 533-. DOI: https://doi.org/10.1186/s12913-020-05294-3

Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda; (2018) Non-parametric frailty Cox models for hierarchical time-to-event data. Biostatistics, 21 (3). pp. 531-544. ISSN 1465-4644 DOI: https://doi.org/10.1093/biostatistics/kxy071

Geneletti, Sara; O'Keeffe, Aidan G; Sharples, Linda D; Richardson, Sylvia; Baio, Gianluca; (2015) Bayesian regression discontinuity designs: incorporating clinical knowledge in the causal analysis of primary care data. Statistics in medicine, 34 (15). pp. 2334-2352. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.6486

Giraud, Kimberly; Pontin, Megan; Sharples, Linda D; Fletcher, Paul; Dalgleish, Tim; Eden, Allaina; Jenkins, David P; Vuylsteke, Alain; (2016) Use of a Structured Mirrors Intervention Does Not Reduce Delirium Incidence But May Improve Factual Memory Encoding in Cardiac Surgical ICU Patients Aged Over 70 Years: A Pilot Time-Cluster Randomized Controlled Trial. Frontiers in aging neuroscience, 8 (SEP). 228-. ISSN 1663-4365 DOI: https://doi.org/10.3389/fnagi.2016.00228

Goldsmith, Kimberley A; Dyer, Matthew T; Buxton, Martin J; Sharples, Linda D; (2010) Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease. HEALTH AND QUALITY OF LIFE OUTCOMES, 8 (1). 54-. ISSN 1477-7525 DOI: https://doi.org/10.1186/1477-7525-8-54

Goldsmith, Kimberley A; Dyer, Matthew T; Schofield, Peter M; Buxton, Martin J; Sharples, Linda D; (2009) Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions. HEALTH AND QUALITY OF LIFE OUTCOMES, 7 (1). 96-. ISSN 1477-7525 DOI: https://doi.org/10.1186/1477-7525-7-96

Gray, Joanne; McCarthy, Andrew; Samarakoon, Dilupa; McMeekin, Peter; Sharples, Linda; Sastry, Priya; Crawshaw, Paul; Bicknell, Colin; ETTAA Collaborative Group; (2024) Costs of endovascular and open repair of thoracic aortic aneurysms. The British journal of surgery, 111 (1). znad378-. ISSN 0007-1323 DOI: https://doi.org/10.1093/bjs/znad378

Greenwood, John P; Ripley, David P; Berry, Colin; McCann, Gerry P; Plein, Sven; Bucciarelli-Ducci, Chiara; Dall'Armellina, Erica; Prasad, Abhiram; Bijsterveld, Petra; Foley, James R; +8 more... Mangion, Kenneth; Sculpher, Mark; Walker, Simon; Everett, Colin C; Cairns, David A; Sharples, Linda D; Brown, Julia M; CE-MARC 2 Investigators; (2016) Effect of Care Guided by Cardiovascular Magnetic Resonance, Myocardial Perfusion Scintigraphy, or NICE Guidelines on Subsequent Unnecessary Angiography Rates: The CE-MARC 2 Randomized Clinical Trial. JAMA, 316 (10). pp. 1051-1060. ISSN 0098-7484 DOI: https://doi.org/10.1001/jama.2016.12680

Gregson, John; Sharples, Linda; Stone, Gregg W; Burman, Carl-Fredrik; Öhrn, Fredrik; Pocock, Stuart; (2019) Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials: JACC Review Topic of the Week. Journal of the American College of Cardiology, 74 (16). pp. 2102-2112. ISSN 0735-1097 DOI: https://doi.org/10.1016/j.jacc.2019.08.1034

Ieva, Francesca; Gale, Chris P; Sharples, Linda D; (2014) Contemporary roles of registries in clinical cardiology: when do we need randomized trials? Expert review of cardiovascular therapy, 12 (12). pp. 1383-1386. ISSN 1477-9072 DOI: https://doi.org/10.1586/14779072.2015.982096 Full text not available from this repository.

Ieva, Francesca; Jackson, Christopher H; Sharples, Linda D; (2015) Multi-state modelling of repeated hospitalisation and death in patients with heart failure: The use of large administrative databases in clinical epidemiology. Statistical methods in medical research, 26 (3). pp. 1350-1372. ISSN 0962-2802 DOI: https://doi.org/10.1177/0962280215578777 Full text not available from this repository.

Jackson, Christopher H; Jit, Mark; Sharples, Linda D; De Angelis, Daniela; (2013) Calibration of complex models through Bayesian evidence synthesis: a demonstration and tutorial. Medical decision making, 35 (2). pp. 148-161. ISSN 0272-989X DOI: https://doi.org/10.1177/0272989X13493143 Full text not available from this repository.

Jackson, Christopher H; Sharples, Linda D; Thompson, Simon G; (2010) Structural and parameter uncertainty in Bayesian cost-effectiveness models. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES C-APPLIED STATISTICS, 59 (2). pp. 233-253. ISSN 0035-9254 DOI: https://doi.org/10.1111/j.1467-9876.2009.00684.x

Jackson, Christopher H; Thompson, Simon G; Sharples, Linda D; (2009) Accounting for uncertainty in health economic decision models by using model averaging. JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 172 (2). pp. 383-404. ISSN 0964-1998 DOI: https://doi.org/10.1111/j.1467-985X.2008.00573.x

Jackson, Christopher; Stevens, John; Ren, Shijie; Latimer, Nick; Bojke, Laura; Manca, Andrea; Sharples, Linda; (2016) Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods. Medical decision making, 37 (4). pp. 377-390. ISSN 0272-989X DOI: https://doi.org/10.1177/0272989X16639900

Jackson, Dan; Zhang, Fanni; Burman, Carl-Fredrik; Sharples, Linda; (2024) Bayesian Solutions for Assessing Differential Effects in Biomarker Positive and Negative Subgroups. Pharmaceutical statistics. ISSN 1539-1604 DOI: https://doi.org/10.1002/pst.2456

Khan, Sadia N; McNab, Duncan C; Sharples, Linda D; Freeman, Carol J; Hardy, Ian; Stone, David L; Schofield, Peter M; (2008) A study to assess changes in myocardial perfusion after treatment with spinal cord stimulation and percutaneous myocardial laser revascularisation; data from a randomised trial. TRIALS, 9 (1). 9-. ISSN 1745-6215 DOI: https://doi.org/10.1186/1745-6215-9-9

Kosmoliaptsis, Vasilios; Gjorgjimajkoska, Olivera; Sharples, Linda D; Chaudhry, Afzal N; Chatzizacharias, Nikolaos; Peacock, Sarah; Torpey, Nicholas; Bolton, Eleanor M; Taylor, Craig J; Bradley, J Andrew; (2014) Impact of donor mismatches at individual HLA-A, -B, -C, -DR, and -DQ loci on the development of HLA-specific antibodies in patients listed for repeat renal transplantation. Kidney international, 86 (5). pp. 1039-1048. ISSN 0085-2538 DOI: https://doi.org/10.1038/ki.2014.106 Full text not available from this repository.

Li, Shuping J; Seedher, Tara; Sharples, Linda D; Benton, Sally C; Mathews, Christopher; Gabe, Rhian; Sasieni, Peter; Duffy, Stephen W; (2022) Impact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study. British Journal of Cancer, 127 (8). pp. 1525-1533. ISSN 0007-0920 DOI: https://doi.org/10.1038/s41416-022-01919-y

Li, Shuping J; Sharples, Linda D; Benton, Sally C; Blyuss, Oleg; Mathews, Christopher; Sasieni, Peter; Duffy, Stephen W; (2020) Faecal immunochemical testing in bowel cancer screening: Estimating outcomes for different diagnostic policies. Journal of Medical Screening, 28 (3). pp. 277-285. ISSN 0969-1413 DOI: https://doi.org/10.1177/0969141320980501

Luckraz, Heyman; Sharples, Linda D; Charman, Susan C; Tsui, Steven SL; Wallwork, John; Parameshwar, Jayan; Large, Stephen R; (2005) Does heart transplantation confer survival benefit in all risk groups? The Journal of heart and lung transplantation, 24 (9). pp. 1231-1234. ISSN 1053-2498 DOI: https://doi.org/10.1016/j.healun.2004.08.008 Full text not available from this repository.

Mackay, JH; Nashef, SAM; Klein, AA; Papachristofi, O; Sharples, LD; Fletcher, SN; Association of Cardiothoracic Anaesthetists (ACTA); (2016) Anaesthetist contribution to mortality after cardiac surgery - a reply. Anaesthesia, 71 (5). pp. 599-601. ISSN 0003-2409 DOI: https://doi.org/10.1111/anae.13475 Full text not available from this repository.

Mansukhani, Raoul; Frimley, Lauren; Shakur-Still, Haleema; Sharples, Linda; Roberts, Ian; (2020) Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results. Trials, 21 (1). 681-. DOI: https://doi.org/10.1186/s13063-020-04623-5

Matthews, Claire; Freeman, Carol; Sharples, Linda D; Fox-Rushby, Julia; Tod, Angela; Maskell, Nicholas A; Edwards, John G; Coonar, Aman S; Sivasothy, Pasupathy; Hughes, Victoria; +3 more... Rahman, Najib M; Waller, David A; Rintoul, Robert Campbell; (2019) MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial. BMJ Open Respiratory Research, 6 (1). e000368-. DOI: https://doi.org/10.1136/bmjresp-2018-000368

Matthews, John NS; Bazakou, Sofia; Henderson, Robin; Sharples, Linda D; (2023) Contrasting principal stratum and hypothetical strategy estimands in multi-period crossover trials with incomplete data. Biometrics, 79 (3). pp. 1896-1907. ISSN 0006-341X DOI: https://doi.org/10.1111/biom.13777 Item availability may be restricted.

McCarthy, Andrew; Gray, Joanne; Sastry, Priya; Sharples, Linda; Vale, Luke; Cook, Andrew; Mcmeekin, Peter; Freeman, Carol; Catarino, Pedro; Large, Stephen; (2021) Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms. BMJ Open, 11 (3). e043323-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2020-043323

Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; +17 more... MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David; (2020) Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. International Journal of Cardiology, 308. pp. 67-72. ISSN 0167-5273 DOI: https://doi.org/10.1016/j.ijcard.2020.03.059

Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; +17 more... MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David; (2020) Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. International Journal of Cardiology, 308. pp. 67-72. ISSN 0167-5273 DOI: https://doi.org/10.1016/j.ijcard.2020.03.059

Nair, SK; Sudarshan, CD; Thorpe, BS; Singh, J; Pillay, T; Catarino, P; Valchanov, K; Codispoti, M; Dunning, J; Abu-Omar, Y; +5 more... Moorjani, N; Matthews, C; Freeman, CJ; Fox-Rushby, JA; Sharples, LD; (2018) Mini-Stern Trial: A randomised trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. The Journal of thoracic and cardiovascular surgery. ISSN 0022-5223 DOI: https://doi.org/10.1016/j.jtcvs.2018.05.057

Nair, Sukumaran K; Sudarshan, Catherine D; Thorpe, Benjamin S; Singh, Jeshika; Pillay, Thasee; Catarino, Pedro; Valchanov, Kamen; Codispoti, Massimiliano; Dunning, John; Abu-Omar, Yasir; +5 more... Moorjani, Narain; Matthews, Claire; Freeman, Carol J; Fox-Rushby, Julia A; Sharples, Linda D; (2018) Mini-Stern Trial: A randomized trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. The Journal of thoracic and cardiovascular surgery, 156 (6). 2124-2132.e31. ISSN 0022-5223 DOI: https://doi.org/10.1016/j.jtcvs.2018.05.057 Full text not available from this repository.

Nashef, Samer AM; Fynn, Simon; Abu-Omar, Yasir; Spyt, Tomasz J; Mills, Christine; Everett, Colin C; Fox-Rushby, Julia; Singh, Jeshika; Dalrymple-Hay, Malcolm; Sudarshan, Catherine; +4 more... Codispoti, Massimiliano; Braidley, Peter; Wells, Francis C; Sharples, Linda D; (2018) Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. European journal of cardio-thoracic surgery, 54 (4). pp. 729-737. ISSN 1010-7940 DOI: https://doi.org/10.1093/ejcts/ezy165

Nashef, Samer AM; Sharples, Linda D; (2022) Reply to García-Villarreal et al. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 63 (1). ezac586-. ISSN 1010-7940 DOI: https://doi.org/10.1093/ejcts/ezac586

Navarro Coy, Nuria C; Brown, Sarah; Bosworth, Ailsa; Davies, Claire T; Emery, Paul; Everett, Colin C; Fernandez, Catherine; Gray, Janine C; Hartley, Suzanne; Hulme, Claire; +8 more... Keenan, Anne-Maree; McCabe, Christopher; Redmond, Anthony; Reynolds, Catherine; Scott, David; Sharples, Linda D; Pavitt, Sue; Buch, Maya H; (2014) The 'Switch' study protocol: a randomised-controlled trial of switching to an alternative tumour-necrosis factor (TNF)-inhibitor drug or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-inhibitor drug. BMC musculoskeletal disorders, 15 (1). 452-. ISSN 1471-2474 DOI: https://doi.org/10.1186/1471-2474-15-452

O'Keeffe, Aidan G; Geneletti, Sara; Baio, Gianluca; Sharples, Linda D; Nazareth, Irwin; Petersen, Irene; (2014) Regression discontinuity designs: an approach to the evaluation of treatment efficacy in primary care using observational data. BMJ (Clinical research ed), 349 (sep08 ). g5293-. ISSN 0959-8138 DOI: https://doi.org/10.1136/bmj.g5293 Full text not available from this repository.

Ortmann, Erik; Besser, Martin W; Sharples, Linda D; Gerrard, Caroline; Berman, Marius; Jenkins, David P; Klein, Andrew A; (2015) An exploratory cohort study comparing prothrombin complex concentrate and fresh frozen plasma for the treatment of coagulopathy after complex cardiac surgery. Anesthesia and analgesia, 121 (1). pp. 26-33. ISSN 0003-2999 DOI: https://doi.org/10.1213/ANE.0000000000000689 Full text not available from this repository.

Papachristofi, O; Sharples, LD; Mackay, JH; Nashef, SAM; Fletcher, SN; Klein, AA; Association of Cardiothoracic Anaesthetists (ACTA); (2015) The contribution of the anaesthetist to risk-adjusted mortality after cardiac surgery. Anaesthesia, 71 (2). pp. 138-146. ISSN 0003-2409 DOI: https://doi.org/10.1111/anae.13291

Papachristofi, Olympia; Jenkins, David; Sharples, Linda D; (2016) Assessment of learning curves in complex surgical interventions: a consecutive case-series study. Trials, 17 (1). 266-. ISSN 1745-6215 DOI: https://doi.org/10.1186/s13063-016-1383-4

Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick S; Sharples, Linda D; Association for Cardiothoracic Anaesthesia and Critical Care (AC; (2018) Does the "Weekend Effect" for Postoperative Mortality Stand Up to Scrutiny? Association for Cardiothoracic Anesthesia and Critical Care Cohort Study of 110,728 Cardiac Surgical Patients. Journal of cardiothoracic and vascular anesthesia, 32 (5). pp. 2178-2186. ISSN 1053-0770 DOI: https://doi.org/10.1053/j.jvca.2018.04.015

Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick; Sharples, Linda D; Association of Cardiothoracic Anaesthesia and Critical Care (ACT; (2017) Effect of individual patient risk, centre, surgeon and anaesthetist on length of stay in hospital after cardiac surgery: Association of Cardiothoracic Anaesthesia and Critical Care (ACTACC) consecutive cases series study of 10 UK specialist centres. BMJ open, 7 (9). e016947-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2017-016947

Papachristofi, Olympia; Klein, Andrew; Sharples, Linda; (2016) Evaluation of the effects of multiple providers in complex surgical interventions. Statistics in medicine, 35 (28). pp. 5222-5246. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.7057 Full text not available from this repository.

Perreas, KG; McNeil, K; Charman, S; Sharples, LD; Wreghitt, T; Wallwork, J; (2005) Extended ganciclovir prophylaxis in lung transplantation. The Journal of heart and lung transplantation, 24 (5). pp. 583-587. ISSN 1053-2498 DOI: https://doi.org/10.1016/j.healun.2004.02.005 Full text not available from this repository.

Pouncey, Anna L; Patel, Dhvni; Freeman, Carol; Sastry, Priya; Bicknell, Colin; Large, Stephen R; Sharples, Linda D; (2024) Inequalities for women diagnosed with distal arch and descending thoracic aortic aneurysms: results from the Effective Treatments for Thoracic Aortic Aneurysms (ETTAA) cohort study. The British journal of surgery, 111 (8). znae185-. ISSN 0007-1323 DOI: https://doi.org/10.1093/bjs/znae185

Quinnell, Timothy G; Bennett, Maxine; Jordan, Jake; Clutterbuck-James, Abigail L; Davies, Michael G; Smith, Ian E; Oscroft, Nicholas; Pittman, Marcus A; Cameron, Malcolm; Chadwick, Rebecca; +4 more... Morrell, Mary J; Glover, Matthew J; Fox-Rushby, Julia A; Sharples, Linda D; (2014) A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO). Thorax, 69 (10). pp. 938-945. ISSN 0040-6376 DOI: https://doi.org/10.1136/thoraxjnl-2014-205464 Full text not available from this repository.

Rintoul, Robert C; Glover, Matthew J; Jackson, Christopher; Hughes, Victoria; Tournoy, Kurt G; Dooms, Christophe; Annema, Jouke T; Sharples, Linda D; (2013) Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective. Thorax, 69 (7). pp. 679-681. ISSN 0040-6376 DOI: https://doi.org/10.1136/thoraxjnl-2013-204374 Full text not available from this repository.

Rintoul, Robert C; Ritchie, Andrew J; Edwards, John G; Waller, David A; Coonar, Aman S; Bennett, Maxine; Lovato, Eleonora; Hughes, Victoria; Fox-Rushby, Julia A; Sharples, Linda D; +1 more... MesoVATS Collaborators; (2014) Efficacy and cost of video-assisted thoracoscopic partial pleurectomy versus talc pleurodesis in patients with malignant pleural mesothelioma (MesoVATS): an open-label, randomised, controlled trial. Lancet, 384 (9948). pp. 1118-1127. ISSN 0140-6736 DOI: https://doi.org/10.1016/S0140-6736(14)60418-9 Full text not available from this repository.

Sastry, Priya; Hughes, Victoria; Hayes, Paul; Vallabhaneni, Srinivasa; Sharples, Linda; Thompson, Matt; Catarino, Pedro; Moorjani, Narain; Vale, Luke; Gray, Joanne; +4 more... Cook, Andrew; Elefteriades, John A; Large, Stephen R; ETTAA Collaborators; (2015) The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. BMJ open, 5 (6). e008147-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2015-008147

Sehjal, Jyoti; Sharples, Linda D; Keogh, Ruth H; Walker, Kate; Prachalias, Andreas; Heaton, Nigel; Ivanics, Tommy; van der Meulen, Jan; Wallace, David; (2022) Time-varying Comparison of All-cause Mortality After Liver Transplantation Between Recipients With and Without Hepatocellular Carcinoma: A Population-based Cohort Study Using the United Kingdom Liver Transplant Registry. Transplantation, 106 (11). e464-e475. ISSN 0041-1337 DOI: https://doi.org/10.1097/TP.0000000000004282

Sharma, Vishal; Coleman, Susanne; Nixon, Jane; Sharples, Linda; Hamilton-Shield, Julian; Rutter, Harry; Bryant, Maria; (2019) A systematic review and meta-analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years. Obesity Reviews, 20 (10). pp. 1341-1349. ISSN 1467-7881 DOI: https://doi.org/10.1111/obr.12904

Sharples, Linda D; (2018) The role of statistics in the era of big data: Electronic health records for healthcare research. Statistics & probability letters, 136. pp. 105-110. ISSN 0167-7152 DOI: https://doi.org/10.1016/j.spl.2018.02.044

Sharples, Linda D; Anagnostopoulou, Vasiliki; Pouncey, Anna L; Freeman, Carol; McCarthy, Andrew; Gray, Joanne; McMeekin, Peter; Sastry, Priya; Vale, Luke; Bicknell, Colin; +1 more... Large, Stephen R; (2024) Longitudinal health-related quality of life in people with thoracic aortic aneurysms. The British journal of surgery, 111 (9). znae228. ISSN 0007-1323 DOI: https://doi.org/10.1093/bjs/znae228

Sharples, Linda D; Clutterbuck-James, Abigail L; Glover, Matthew J; Bennett, Maxine S; Chadwick, Rebecca; Pittman, Marcus A; Quinnell, Timothy G; (2015) Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea. Sleep medicine reviews, 27. pp. 108-124. ISSN 1087-0792 DOI: https://doi.org/10.1016/j.smrv.2015.05.003

Sharples, Linda D; Mills, Christine; Chiu, Yi-Da; Fynn, Simon; Holcombe, Helen M; Nashef, Samer AM; (2022) Five-year results of Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. European journal of cardio-thoracic surgery, 62 (5). ISSN 1010-7940 DOI: https://doi.org/10.1093/ejcts/ezac181

Sharples, Linda D; Quinnell, Timothy G; TOMADO investigators; (2015) Response to comments on "Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea". Sleep medicine reviews, 27. pp. 41-42. ISSN 1087-0792 DOI: https://doi.org/10.1016/j.smrv.2015.08.001 Full text not available from this repository.

Sharples, Linda; Everett, Colin; Singh, Jeshika; Mills, Christine; Spyt, Tom; Abu-Omar, Yasir; Fynn, Simon; Thorpe, Benjamin; Stoneman, Victoria; Goddard, Hester; +2 more... Fox-Rushby, Julia; Nashef, Samer; (2018) Amaze: a double-blind, multicentre randomised controlled trial to investigate the clinical effectiveness and cost-effectiveness of adding an ablation device-based maze procedure as an adjunct to routine cardiac surgery for patients with pre-existing atrial fibrillation. Health technology assessment (Winchester, England), 22 (19). pp. 1-132. ISSN 1366-5278 DOI: https://doi.org/10.3310/hta22190

Sharples, Linda; Papachristofi, Olympia; Rex, Saleema; Landau, Sabine; (2020) Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis. Clinical Trials, 17 (6). pp. 654-663. ISSN 1740-7745 DOI: https://doi.org/10.1177/1740774520947644

Sharples, Linda; Sastry, Priya; Freeman, Carol; Bicknell, Colin; Chiu, Yi Da; Vallabhaneni, Srinivasa Rao; Cook, Andrew; Gray, Joanne; McCarthy, Andrew; McMeekin, Peter; +2 more... Vale, Luke; Large, Stephen; (2021) Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study. European heart journal, 43 (25). pp. 2356-2369. ISSN 0195-668X DOI: https://doi.org/10.1093/eurheartj/ehab784

Sharples, Linda; Sastry, Priya; Freeman, Carol; Gray, Joanne; McCarthy, Andrew; Chiu, Yi-Da; Bicknell, Colin; McMeekin, Peter; Vallabhaneni, S Rao; Cook, Andrew; +2 more... Vale, Luke; Large, Stephen; (2022) Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study. HEALTH TECHNOLOGY ASSESSMENT, 26 (6). pp. 1-166. ISSN 1366-5278 DOI: https://doi.org/10.3310/ABUT7744

Sharples, Linda; Sastry, Priya; Freeman, Carol; Gray, Joanne; McCarthy, Andrew; Chiu, YiDa; Bicknell, Colin; McMeekin, Peter; Vallabheni, S Rao; Cook, Andrew; +2 more... Vale, Luke; Large, Stephen; (2022) Effective Treatments for Thoracic Aortic Aneurysms: A prospective cohort study (ETTAA). Health technology assessment, 26 (6). ISSN 1366-5278 DOI: https://doi.org/10.3310/ABUT7744

Smith, Isabelle L; Nixon, Jane E; Sharples, Linda; (2021) Power and sample size for multistate model analysis of longitudinal discrete outcomes in disease prevention trials. Statistics in Medicine, 40 (8). pp. 1960-1971. DOI: https://doi.org/10.1002/sim.8882

Soares, Marta O; Sharples, Linda; Morton, Alec; Claxton, Karl; Bojke, Laura; (2018) Experiences of Structured Elicitation for Model-Based Cost-Effectiveness Analyses. Value in health, 21 (6). pp. 715-723. ISSN 1098-3015 DOI: https://doi.org/10.1016/j.jval.2018.01.019

Stoica, Serban C; Satchithananda, Duwarakan K; Charman, Susan; Sharples, Linda; King, Robert; Rozario, Chris; Dunning, John; Tsui, Steven S; Wallwork, John; Large, Stephen R; (2002) Swan-Ganz catheter assessment of donor hearts: outcome of organs with borderline hemodynamics. The Journal of heart and lung transplantation, 21 (6). pp. 615-622. ISSN 1053-2498 DOI: https://doi.org/10.1016/s1053-2498(02)00380-7 Full text not available from this repository.

Tanner, Kamaryn T; Daniel, Rhian M; Bilton, Diana; Simmonds, Nicholas J; Sharples, Linda D; Keogh, Ruth H; (2022) Mediation of the total effect of cystic fibrosis-related diabetes on mortality: A UK Cystic Fibrosis Registry cohort study. Diabetic medicine, 39 (11). e14958-. ISSN 0742-3071 DOI: https://doi.org/10.1111/dme.14958

Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H; (2022) Methods of analysis for survival outcomes with time-updated mediators, with application to longitudinal disease registry data. Statistical Methods in Medical Research, 31 (10). pp. 1959-1975. ISSN 0962-2802 DOI: https://doi.org/10.1177/09622802221107104

Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H; (2020) Dynamic Survival Prediction Combining Landmarking with a Machine Learning Ensemble: Methodology and Empirical Comparison. Journal of the Royal Statistical Society Series A: Statistics in Society, 184 (1). pp. 3-30. ISSN 0964-1998 DOI: https://doi.org/10.1111/rssa.12611

Thom, Howard HZ; Jackson, Christopher H; Commenges, Daniel; Sharples, Linda D; (2015) State selection in Markov models for panel data with application to psoriatic arthritis. Statistics in medicine, 34 (16). pp. 2456-2475. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.6460 Full text not available from this repository.

Thom, Howard; Jackson, Chris; Welton, Nicky; Sharples, Linda; (2017) Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. PharmacoEconomics, 35 (9). pp. 951-962. ISSN 1170-7690 DOI: https://doi.org/10.1007/s40273-017-0501-9

Thom, Howard; West, Nicholas EJ; Hughes, Vikki; Dyer, Matthew; Buxton, Martin; Sharples, Linda D; Jackson, Christopher H; Crean, Andrew M; CECaT study group; (2014) Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial. BMJ open, 4 (2). e003419-. ISSN 2044-6055 DOI: https://doi.org/10.1136/bmjopen-2013-003419

Thorpe, Benjamin; Carroll, Orlagh; Sharples, Linda; (2017) Methods for Handling Unobserved Covariates in a Bayesian Update of a Cost-effectiveness Model. Medical decision making, 38 (2). pp. 150-162. ISSN 0272-989X DOI: https://doi.org/10.1177/0272989X17736780

Win, T; Jackson, A; Groves, AM; Sharples, LD; Charman, SC; Laroche, CM; (2006) Comparison of shuttle walk with measured peak oxygen consumption in patients with operable lung cancer. Thorax, 61 (1). pp. 57-60. ISSN 0040-6376 DOI: https://doi.org/10.1136/thx.2005.043547 Full text not available from this repository.

Brown, S; Everett, CC; Naraghi, K; Davies, C; Dawkins, B; Hulme, C; McCabe, C; Pavitt, S; Emery, P; Sharples, L; +1 more... Buch, MH; (2018) Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT. Technical Report. NIHR Journals Library. DOI: https://doi.org/10.3310/hta22340

Edgar, K; (2024) Admission Avoidance Hospital at Home: Extending understanding using trial and observational data. PhD thesis, London School of Hygiene and Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04673425 Item availability may be restricted.

Tanner, KT; (2021) Dynamic Prediction, Mediation and Communication for Survival Outcomes, with applications to Cystic Fibrosis. PhD thesis, London School of Hygiene & Tropical Medicine. DOI: https://doi.org/10.17037/PUBS.04663978

Thom, H; Jackson, C; Welton, N; Sharples, L; (2017) Erratum to: Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. Springer Verlag. DOI: https://doi.org/10.1007/s40273-017-0520-6