New Trypanosoma brucei acting derivatives incorporating 1-(4-phenyl)adamantane and 1-(4-phenoxyphenyl)adamantane

Konstantina Stavropoulou ORCID logo ; Angeliki Kaimaki ; Maria Nikolaou ; Ana K Brown ORCID logo ; Andrew Tsotinis ORCID logo ; Martin C Taylor ORCID logo ; John M Kelly ORCID logo ; Ioannis P Papanastasiou ORCID logo ; (2025) New Trypanosoma brucei acting derivatives incorporating 1-(4-phenyl)adamantane and 1-(4-phenoxyphenyl)adamantane. RSC medicinal chemistry, 16 (6). pp. 2441-2451. ISSN 2632-8682 DOI: 10.1039/d5md00135h
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New 1-(4-phenyl)adamantane and 1-(4-phenoxyphenyl)adamantane derivatives, functionalised with imidazolines, linear amidines, aminoguanylhydrazone and thiosemicarbazone moieties present activity against T. brucei.

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