Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.

Sona Jabang ORCID logo ; Annette Erhart ORCID logo ; Saffiatou Darboe ORCID logo ; Aru-Kumba Baldeh ; Valerie Delforge ; Gabriella Watson ; Ebenezer Foster-Nyarko ORCID logo ; Rasheed Salaudeen ; Bolarinde Lawal ORCID logo ; Grant Mackenzie ORCID logo ; +4 more... Anne Botteaux ; Martin Antonio ORCID logo ; Pierre R Smeesters ; On Behalf Of The Mrcg StrepA Study Group ; (2021) Molecular Epidemiology of Group A Streptococcus Infections in The Gambia. Vaccines, 9 (2). p. 124. DOI: 10.3390/vaccines9020124
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Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.


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