Molecular Epidemiology of Group A Streptococcus Infections in The Gambia.

Jabang, SORCID logo; Erhart, AORCID logo; Darboe, SORCID logo; Baldeh, A; Delforge, V; Watson, G; Foster-Nyarko, EORCID logo; Salaudeen, R; Lawal, BORCID logo; Mackenzie, GORCID logo; +4 more...Botteaux, A; Antonio, MORCID logo; Smeesters, PR; On Behalf Of The Mrcg StrepA Study Group and (2021) Molecular Epidemiology of Group A Streptococcus Infections in The Gambia. Vaccines, 9 (2). p. 124. DOI: 10.3390/vaccines9020124
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Molecular epidemiological data on Group A Streptococcus (GAS) infection in Africa is scarce. We characterized the emm-types and emm-clusters of 433 stored clinical GAS isolates from The Gambia collected between 2004 and 2018. To reduce the potential for strain mistyping, we used a newly published primer for emm-typing. There was considerable strain diversity, highlighting the need for vaccine development offering broad strain protection.


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