Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Howie, Stephen RC; Morris, Gerard AJ; Tokarz, Rafal; Ebruke, Bernard E; Machuka, Eunice M; Ideh, Readon C; Chimah, Osaretin; Secka, Ousman; Townend, John; Dione, Michel; +11 more...Oluwalana, Claire; Njie, Malick; Jallow, Mariatou; Hill, Philip C; Antonio, Martin
; Greenwood, Brian
; Briese, Thomas; Mulholland, Kim
; Corrah, Tumani; Lipkin, W Ian; and Adegbola, Richard A
(2014)
Etiology of severe childhood pneumonia in the Gambia, West Africa, determined by conventional and molecular microbiological analyses of lung and pleural aspirate samples.
Clinical infectious diseases, 59 (5).
pp. 682-685.
ISSN 1058-4838
DOI: 10.1093/cid/ciu384
Molecular analyses of lung aspirates from Gambian children with severe pneumonia detected pathogens more frequently than did culture and showed a predominance of bacteria, principally Streptococcus pneumoniae, >75% being of serotypes covered by current pneumococcal conjugate vaccines. Multiple pathogens were detected frequently, notably Haemophilus influenzae (mostly nontypeable) together with S. pneumoniae.
Item Type | Article |
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ISI | 342921100017 |
Date Deposited | 04 Jun 2014 19:15 |
Explore Further
- GM-Vaccinology Theme
- Dept of Disease Control
- Dept of Infectious Disease Epidemiology & International Health (2023-)
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4130311 (OA Location)
- 10.1093/cid/ciu384 (DOI)
- 24867789 (PubMed)
ORCID: https://orcid.org/0000-0002-4810-1308
ORCID: https://orcid.org/0000-0001-5725-9118
ORCID: https://orcid.org/0000-0001-7947-680X