Items where Author is "Sharples, Linda D"
Number of items: 103.
Bibliographic data only
  • Assessment of survival benefit after lung transplantation by patient diagnosis. (2002) Charman, Susan C; Sharples, Linda D; McNeil, Keith D; Wallwork, John
  • Contemporary roles of registries in clinical cardiology: when do we need randomized trials? (2014) Ieva, Francesca; Gale, Chris P; Sharples, Linda D
  • Multi-state modelling of repeated hospitalisation and death in patients with heart failure: The use of large administrative databases in clinical epidemiology. (2015) Ieva, Francesca; Jackson, Christopher H; Sharples, Linda D
  • Calibration of complex models through Bayesian evidence synthesis: a demonstration and tutorial. (2013) Jackson, Christopher H; Jit, Mark; Sharples, Linda D; De Angelis, Daniela
  • Impact of donor mismatches at individual HLA-A, -B, -C, -DR, and -DQ loci on the development of HLA-specific antibodies in patients listed for repeat renal transplantation. (2014) Kosmoliaptsis, Vasilios; Gjorgjimajkoska, Olivera; Sharples, Linda D; Chaudhry, Afzal N; Chatzizacharias, Nikolaos; Peacock, Sarah; Torpey, Nicholas; Bolton, Eleanor M; Taylor, Craig J; Bradley, J Andrew
  • Does heart transplantation confer survival benefit in all risk groups? (2005) Luckraz, Heyman; Sharples, Linda D; Charman, Susan C; Tsui, Steven SL; Wallwork, John; Parameshwar, Jayan; Large, Stephen R
  • Anaesthetist contribution to mortality after cardiac surgery - a reply. (2016) Mackay, JH; Nashef, SAM; Klein, AA; Papachristofi, O; Sharples, LD; Fletcher, SN; Association of Cardiothoracic Anaesthetists (ACTA)
  • Mini-Stern Trial: A randomized trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. (2018) Nair, Sukumaran K; Sudarshan, Catherine D; Thorpe, Benjamin S; Singh, Jeshika; Pillay, Thasee; Catarino, Pedro; Valchanov, Kamen; Codispoti, Massimiliano; Dunning, John; Abu-Omar, Yasir; Moorjani, Narain; Matthews, Claire; Freeman, Carol J; Fox-Rushby, Julia A; Sharples, Linda D
  • Regression discontinuity designs: an approach to the evaluation of treatment efficacy in primary care using observational data. (2014) O'Keeffe, Aidan G; Geneletti, Sara; Baio, Gianluca; Sharples, Linda D; Nazareth, Irwin; Petersen, Irene
  • An exploratory cohort study comparing prothrombin complex concentrate and fresh frozen plasma for the treatment of coagulopathy after complex cardiac surgery. (2015) Ortmann, Erik; Besser, Martin W; Sharples, Linda D; Gerrard, Caroline; Berman, Marius; Jenkins, David P; Klein, Andrew A
  • Evaluation of the effects of multiple providers in complex surgical interventions. (2016) Papachristofi, Olympia; Klein, Andrew; Sharples, Linda
  • Extended ganciclovir prophylaxis in lung transplantation. (2005) Perreas, KG; McNeil, K; Charman, S; Sharples, LD; Wreghitt, T; Wallwork, J
  • A crossover randomised controlled trial of oral mandibular advancement devices for obstructive sleep apnoea-hypopnoea (TOMADO). (2014) Quinnell, Timothy G; Bennett, Maxine; Jordan, Jake; Clutterbuck-James, Abigail L; Davies, Michael G; Smith, Ian E; Oscroft, Nicholas; Pittman, Marcus A; Cameron, Malcolm; Chadwick, Rebecca; Morrell, Mary J; Glover, Matthew J; Fox-Rushby, Julia A; Sharples, Linda D
  • Cost effectiveness of endosonography versus surgical staging in potentially resectable lung cancer: a health economics analysis of the ASTER trial from a European perspective. (2013) Rintoul, Robert C; Glover, Matthew J; Jackson, Christopher; Hughes, Victoria; Tournoy, Kurt G; Dooms, Christophe; Annema, Jouke T; Sharples, Linda D
  • Efficacy and cost of video-assisted thoracoscopic partial pleurectomy versus talc pleurodesis in patients with malignant pleural mesothelioma (MesoVATS): an open-label, randomised, controlled trial. (2014) Rintoul, Robert C; Ritchie, Andrew J; Edwards, John G; Waller, David A; Coonar, Aman S; Bennett, Maxine; Lovato, Eleonora; Hughes, Victoria; Fox-Rushby, Julia A; Sharples, Linda D; MesoVATS Collaborators
  • Response to comments on "Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea". (2015) Sharples, Linda D; Quinnell, Timothy G; TOMADO investigators
  • Swan-Ganz catheter assessment of donor hearts: outcome of organs with borderline hemodynamics. (2002) Stoica, Serban C; Satchithananda, Duwarakan K; Charman, Susan; Sharples, Linda; King, Robert; Rozario, Chris; Dunning, John; Tsui, Steven S; Wallwork, John; Large, Stephen R
  • State selection in Markov models for panel data with application to psoriatic arthritis. (2015) Thom, Howard HZ; Jackson, Christopher H; Commenges, Daniel; Sharples, Linda D
  • Comparison of shuttle walk with measured peak oxygen consumption in patients with operable lung cancer. (2006) Win, T; Jackson, A; Groves, AM; Sharples, LD; Charman, SC; Laroche, CM
  • Public
  • Recovery of Left Atrial Contractile Function After Maze Surgery in Persistent Longstanding Atrial Fibrillation. (2017) Abu-Omar, Yasir; Thorpe, Benjamin S; Freeman, Carol; Mills, Christine; Stoneman, Victoria EA; Gopalan, Deepa; Rana, Bushra; Spyt, Tomasz J; Sharples, Linda D; Nashef, Samer AM
  • Value of hospital administrative data linked to national cancer registry records to identify metastatic disease at time of primary diagnosis in colorectal cancer patients: a study using national data in England. (2025) Almilaji, Orouba; Sharples, Linda; Aggarwal, Ajay; Cromwell, David; Horgan, Kieran; Braun, Michael; Arnott, Robert; Nossiter, Julie; Kuryba, Angela; Lewin, Alexandra; Rous, Brian; Cowling, Thomas; Meulen, Jan Van Der; Walker, Kate picture_as_pdf
  • The relationship between three-dimensional knee MRI bone shape and total knee replacement-a case control study: data from the Osteoarthritis Initiative. (2016) Barr, Andrew J; Dube, Bright; Hensor, Elizabeth MA; Kingsbury, Sarah R; Peat, George; Bowes, Mike A; Sharples, Linda D; Conaghan, Philip G
  • Survival extrapolation in the presence of cause specific hazards. (2014) Benaglia, Tatiana; Jackson, Christopher H; Sharples, Linda D
  • Performance status score: do patients and their oncologists agree? (2003) Blagden, SP; Charman, SC; Sharples, LD; Magee, LRA; Gilligan, D
  • Improving risk models for patients having emergency bowel cancer surgery using linked electronic health records: a national cohort study. (2024) Blake, Helen A; Sharples, Linda D; Boyle, Jemma M; Kuryba, Angela; Moonesinghe, Suneetha R; Murray, Dave; Hill, James; Fearnhead, Nicola S; van der Meulen, Jan H; Walker, Kate
  • Probabilistic linkage without personal information successfully linked national clinical datasets. (2021) Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate
  • Linkage of multiple electronic health record datasets using a 'spine linkage' approach compared with all 'pairwise linkages'. (2022) Blake, Helen A; Sharples, Linda D; Harron, Katie; van der Meulen, Jan H; Walker, Kate
  • Interventions in randomised controlled trials in surgery: issues to consider during trial design. (2015) Blencowe, Natalie S; Brown, Julia M; Cook, Jonathan A; Metcalfe, Chris; Morton, Dion G; Nicholl, Jon; Sharples, Linda D; Treweek, Shaun; Blazeby, Jane M; Members of the MRC Hub for Trials Methodology Research Network W
  • Reference Case Methods for Expert Elicitation in Health Care Decision Making. (2021) Bojke, Laura; Soares, Marta O; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Chris; Jankovic, Dina; Morton, Alec; Sharples, Linda D; Taylor, Andrea
  • Developing a reference protocol for structured expert elicitation in health-care decision-making: a mixed-methods study. (2021) Bojke, Laura; Soares, Marta; Claxton, Karl; Colson, Abigail; Fox, Aimée; Jackson, Christopher; Jankovic, Dina; Morton, Alec; Sharples, Linda; Taylor, Andrea
  • Randomized Controlled Trial of Rituximab and cost-effectiveness analysis in treating fatigue and oral dryness in primary Sjogren's Syndrome. (2017) Bowman, SJ; Everett, CC; O'Dwyer, JL; Emery, P; Pitzalis, C; Ng, WF; Pease, CT; Price, EJ; Sutcliffe, N; St Gendi, N; Hall, FC; Ruddock, SP; Fernandez, C; Reynolds, C; Hulme, CT; Davies, KA; Edwards, CJ; Lanyon, PC; Moots, RJ; Roussou, E; Giles, IP; Sharples, LD; Bombardieri, M
  • Alternative tumour necrosis factor inhibitors (TNFi) or abatacept or rituximab following failure of initial TNFi in rheumatoid arthritis: the SWITCH RCT. (2018) Brown, S; Everett, CC; Naraghi, K; Davies, C; Dawkins, B; Hulme, C; McCabe, C; Pavitt, S; Emery, P; Sharples, L; Buch, MH
  • Diabetic foot ulcer photography study: a study within a trial to assess the reliability of two-dimensional (2D) photography for the assessment of ulcer healing in patients with diabetes-related foot ulcers-protocol paper. (2024) Brown, Sarah Tess; Collier, Howard; Askew, Lucy; Gilberts, Rachael Mary; Sharples, Linda D; Nixon, Jane; McGinnis, Elizabeth; Backhouse, Michael; Game, Frances; Faulks, Phil; Ransom, Myka; Everett, Colin Charles; Nelson, E Andrea; Russell, David
  • Multiple Interventions for Diabetic Foot Ulcer Treatment Trial (MIDFUT): study protocol for a randomised controlled trial. (2020) Brown, Sarah; Nixon, Jane; Ransom, Myka; Gilberts, Rachael; Dewhirst, Nikki; McGinnis, Elizabeth; Longo, Roberta; Game, Frances; Bojke, Chris; Chadwick, Paul; Chandrasekar, Akila; Chetter, Ian; Collier, Howard; Fernandez, Catherine; Homer-Vanniasinkam, Shervanthi; Jude, Edward; Leigh, Richard; Lomas, Richard; Vowden, Peter; Wason, James; Sharples, Linda; Russell, David
  • Emulating an Existing Trial of Treatments for Prostate Cancer Using Real-World Data: Challenges and lessons learned. (2025) Chesang, Caroline; Sharples, Linda D; Gray, Christen M; Nossiter, Julie; van der Meulen, Jan; Cowling, Thomas E; Keogh, Ruth H
  • The INVEST project: investigating the use of evidence synthesis in the design and analysis of clinical trials. (2017) Clayton, Gemma L; Smith, Isabelle L; Higgins, Julian PT; Mihaylova, Borislava; Thorpe, Benjamin; Cicero, Robert; Lokuge, Kusal; Forman, Julia R; Tierney, Jayne F; White, Ian R; Sharples, Linda D; Jones, Hayley E
  • One-year mortality of colorectal cancer patients: development and validation of a prediction model using linked national electronic data. (2020) Cowling, Thomas E; Bellot, Alexis; Boyle, Jemma; Walker, Kate; Kuryba, Angela; Galbraith, Sarah; Aggarwal, Ajay; Braun, Michael; Sharples, Linda D; van der Meulen, Jan
  • Logistic regression and machine learning predicted patient mortality from large sets of diagnosis codes comparably. (2020) Cowling, Thomas E; Cromwell, David A; Bellot, Alexis; Sharples, Linda D; van der Meulen, Jan
  • A novel approach selected small sets of diagnosis codes with high prediction performance in large healthcare datasets. (2020) Cowling, Thomas E; Cromwell, David A; Sharples, Linda D; van der Meulen, Jan
  • Survival extrapolation using the poly-Weibull model. (2011) Demiris, Nikolaos; Lunn, David; Sharples, Linda D
  • Sex-related differences in left ventricular remodeling in severe aortic stenosis and reverse remodeling after aortic valve replacement: A cardiovascular magnetic resonance study. (2016) Dobson, Laura E; Fairbairn, Timothy A; Musa, Tarique A; Uddin, Akhlaque; Mundie, Cheryl A; Swoboda, Peter P; Ripley, David P; McDiarmid, Adam K; Erhayiem, Bara; Garg, Pankaj; Malkin, Christopher J; Blackman, Daniel J; Sharples, Linda D; Plein, Sven; Greenwood, John P
  • Clinical and cost-effectiveness analysis of an open label, single-centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial. (2008) Dyer, MT; Goldsmith, KA; Khan, SN; Sharples, LD; Freeman, C; Hardy, I; Buxton, MJ; Schofield, PM
  • Frequentist rules for regulatory approval of subgroups in phase III trials: A fresh look at an old problem. (2021) Edgar, K; Jackson, D; Rhodes, K; Duffy, T; Burman, C-F; Sharples, LD
  • Including random centre effects in design, analysis and presentation of multi-centre trials. (2021) Edgar, Kate; Roberts, Ian; Sharples, Linda
  • Evaluation of the impact of the GRACE risk score on the management and outcome of patients hospitalised with non-ST elevation acute coronary syndrome in the UK: protocol of the UKGRIS cluster-randomised registry-based trial. (2019) Everett, Colin C; Fox, Keith Aa; Reynolds, Catherine; Fernandez, Catherine; Sharples, Linda; Stocken, Deborah D; Carruthers, Kathryn; Hemingway, Harry; Yan, Andrew T; Goodman, Shaun G; Brieger, David; Chew, Derek P; Gale, Chris P
  • Rationale and design of the LIBERATES trial: Protocol for a randomised controlled trial of flash glucose monitoring for optimisation of glycaemia in individuals with type 2 diabetes and recent myocardial infarction. (2020) Everett, Colin C; Reynolds, Catherine; Fernandez, Catherine; Stocken, Deborah D; Sharples, Linda D; Sathyapalan, Thozhukat; Heller, Simon; Storey, Robert F; Ajjan, Ramzi A
  • Effect of rituximab on a salivary gland ultrasound score in primary Sjögren's syndrome: results of the TRACTISS randomised double-blind multicentre substudy. (2017) Fisher, Benjamin A; Everett, Colin C; Rout, John; O'Dwyer, John L; Emery, Paul; Pitzalis, Costantino; Ng, Wan-Fai; Carr, Andrew; Pease, Colin T; Price, Elizabeth J; Sutcliffe, Nurhan; Makdissi, Jimmy; Tappuni, Anwar R; Gendi, Nagui ST; Hall, Frances C; Ruddock, Sharon P; Fernandez, Catherine; Hulme, Claire T; Davies, Kevin A; Edwards, Christopher John; Lanyon, Peter C; Moots, Robert J; Roussou, Euthalia; Richards, Andrea; Sharples, Linda D; Bombardieri, Michele; Bowman, Simon J
  • Effectiveness of GRACE risk score in patients admitted to hospital with non-ST elevation acute coronary syndrome (UKGRIS): parallel group cluster randomised controlled trial. (2023) Gale, Chris P; Stocken, Deborah D; Aktaa, Suleman; Reynolds, Catherine; Gilberts, Rachael; Brieger, David; Carruthers, Kathryn; Chew, Derek P; Goodman, Shaun G; Fernandez, Catherine; Sharples, Linda D; Yan, Andrew T; Fox, Keith
  • Non-parametric frailty Cox models for hierarchical time-to-event data. (2018) Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda
  • Evaluating the effect of healthcare providers on the clinical path of heart failure patients through a semi-Markov, multi-state model. (2020) Gasperoni, Francesca; Ieva, Francesca; Paganoni, Anna Maria; Jackson, Christopher H; Sharples, Linda
  • Bayesian regression discontinuity designs: incorporating clinical knowledge in the causal analysis of primary care data. (2015) Geneletti, Sara; O'Keeffe, Aidan G; Sharples, Linda D; Richardson, Sylvia; Baio, Gianluca
  • Use of a Structured Mirrors Intervention Does Not Reduce Delirium Incidence But May Improve Factual Memory Encoding in Cardiac Surgical ICU Patients Aged Over 70 Years: A Pilot Time-Cluster Randomized Controlled Trial. (2016) Giraud, Kimberly; Pontin, Megan; Sharples, Linda D; Fletcher, Paul; Dalgleish, Tim; Eden, Allaina; Jenkins, David P; Vuylsteke, Alain
  • Mapping of the EQ-5D index from clinical outcome measures and demographic variables in patients with coronary heart disease. (2010) Goldsmith, Kimberley A; Dyer, Matthew T; Buxton, Martin J; Sharples, Linda D
  • Relationship between the EQ-5D index and measures of clinical outcomes in selected studies of cardiovascular interventions. (2009) Goldsmith, Kimberley A; Dyer, Matthew T; Schofield, Peter M; Buxton, Martin J; Sharples, Linda D
  • Costs of endovascular and open repair of thoracic aortic aneurysms. (2024) Gray, Joanne; McCarthy, Andrew; Samarakoon, Dilupa; McMeekin, Peter; Sharples, Linda; Sastry, Priya; Crawshaw, Paul; Bicknell, Colin; ETTAA Collaborative Group
  • Effect of Care Guided by Cardiovascular Magnetic Resonance, Myocardial Perfusion Scintigraphy, or NICE Guidelines on Subsequent Unnecessary Angiography Rates: The CE-MARC 2 Randomized Clinical Trial. (2016) Greenwood, John P; Ripley, David P; Berry, Colin; McCann, Gerry P; Plein, Sven; Bucciarelli-Ducci, Chiara; Dall'Armellina, Erica; Prasad, Abhiram; Bijsterveld, Petra; Foley, James R; Mangion, Kenneth; Sculpher, Mark; Walker, Simon; Everett, Colin C; Cairns, David A; Sharples, Linda D; Brown, Julia M; CE-MARC 2 Investigators
  • Nonproportional Hazards for Time-to-Event Outcomes in Clinical Trials: JACC Review Topic of the Week. (2019) Gregson, John; Sharples, Linda; Stone, Gregg W; Burman, Carl-Fredrik; Öhrn, Fredrik; Pocock, Stuart
  • Structural and parameter uncertainty in Bayesian cost-effectiveness models. (2010) Jackson, Christopher H; Sharples, Linda D; Thompson, Simon G
  • Accounting for uncertainty in health economic decision models by using model averaging. (2009) Jackson, Christopher H; Thompson, Simon G; Sharples, Linda D
  • Extrapolating Survival from Randomized Trials Using External Data: A Review of Methods. (2016) Jackson, Christopher; Stevens, John; Ren, Shijie; Latimer, Nick; Bojke, Laura; Manca, Andrea; Sharples, Linda
  • Bayesian Solutions for Assessing Differential Effects in Biomarker Positive and Negative Subgroups. (2024) Jackson, Dan; Zhang, Fanni; Burman, Carl-Fredrik; Sharples, Linda
  • A study to assess changes in myocardial perfusion after treatment with spinal cord stimulation and percutaneous myocardial laser revascularisation; data from a randomised trial. (2008) Khan, Sadia N; McNab, Duncan C; Sharples, Linda D; Freeman, Carol J; Hardy, Ian; Stone, David L; Schofield, Peter M
  • Impact of changes to the interscreening interval and faecal immunochemical test threshold in the national bowel cancer screening programme in England: results from the FIT pilot study. (2022) Li, Shuping J; Seedher, Tara; Sharples, Linda D; Benton, Sally C; Mathews, Christopher; Gabe, Rhian; Sasieni, Peter; Duffy, Stephen W
  • Faecal immunochemical testing in bowel cancer screening: Estimating outcomes for different diagnostic policies. (2020) Li, Shuping J; Sharples, Linda D; Benton, Sally C; Blyuss, Oleg; Mathews, Christopher; Sasieni, Peter; Duffy, Stephen W
  • Accuracy of time to treatment estimates in the CRASH-3 clinical trial: impact on the trial results. (2020) Mansukhani, Raoul; Frimley, Lauren; Shakur-Still, Haleema; Sharples, Linda; Roberts, Ian
  • MesoTRAP: a feasibility study that includes a pilot clinical trial comparing video-assisted thoracoscopic partial pleurectomy decortication with indwelling pleural catheter in patients with trapped lung due to malignant pleural mesothelioma designed to address recruitment and randomisation uncertainties and sample size requirements for a phase III trial. (2019) Matthews, Claire; Freeman, Carol; Sharples, Linda D; Fox-Rushby, Julia; Tod, Angela; Maskell, Nicholas A; Edwards, John G; Coonar, Aman S; Sivasothy, Pasupathy; Hughes, Victoria; Rahman, Najib M; Waller, David A; Rintoul, Robert Campbell
  • Systematic review of endovascular stent grafting versus open surgical repair for the elective treatment of arch/descending thoracic aortic aneurysms. (2021) McCarthy, Andrew; Gray, Joanne; Sastry, Priya; Sharples, Linda; Vale, Luke; Cook, Andrew; Mcmeekin, Peter; Freeman, Carol; Catarino, Pedro; Large, Stephen
  • Trial emulation to assess the effect of surgery on survival when there are competing risks, with application to patients with thoracic aortic aneurysms. (2025) Murray, James; Chesang, Caroline; Large, Steve; Bicknell, Colin; Freeman, Carol; Keogh, Ruth H; Sharples, Linda D picture_as_pdf
  • Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. (2020) Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David
  • Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis. (2020) Myat, Aung; Papachristofi, Olympia; Trivedi, Uday; Bapat, Vinayak; Young, Christopher; de Belder, Adam; Cockburn, James; Baumbach, Andreas; Banning, Adrian P; Blackman, Daniel J; MacCarthy, Philip; Mullen, Michael; Muir, Douglas F; Nolan, James; Zaman, Azfar; de Belder, Mark; Cox, Ian; Kovac, Jan; Brecker, Stephen; Turner, Mark; Khogali, Saib; Malik, Iqbal; Redwood, Simon; Prendergast, Bernard; Ludman, Peter; Sharples, Linda; Hildick-Smith, David
  • Mini-Stern Trial: A randomised trial comparing mini-sternotomy to full median sternotomy for aortic valve replacement. (2018) Nair, SK; Sudarshan, CD; Thorpe, BS; Singh, J; Pillay, T; Catarino, P; Valchanov, K; Codispoti, M; Dunning, J; Abu-Omar, Y; Moorjani, N; Matthews, C; Freeman, CJ; Fox-Rushby, JA; Sharples, LD
  • Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. (2018) Nashef, Samer AM; Fynn, Simon; Abu-Omar, Yasir; Spyt, Tomasz J; Mills, Christine; Everett, Colin C; Fox-Rushby, Julia; Singh, Jeshika; Dalrymple-Hay, Malcolm; Sudarshan, Catherine; Codispoti, Massimiliano; Braidley, Peter; Wells, Francis C; Sharples, Linda D
  • Reply to García-Villarreal et al. (2022) Nashef, Samer AM; Sharples, Linda D
  • The 'Switch' study protocol: a randomised-controlled trial of switching to an alternative tumour-necrosis factor (TNF)-inhibitor drug or abatacept or rituximab in patients with rheumatoid arthritis who have failed an initial TNF-inhibitor drug. (2014) Navarro Coy, Nuria C; Brown, Sarah; Bosworth, Ailsa; Davies, Claire T; Emery, Paul; Everett, Colin C; Fernandez, Catherine; Gray, Janine C; Hartley, Suzanne; Hulme, Claire; Keenan, Anne-Maree; McCabe, Christopher; Redmond, Anthony; Reynolds, Catherine; Scott, David; Sharples, Linda D; Pavitt, Sue; Buch, Maya H
  • The contribution of the anaesthetist to risk-adjusted mortality after cardiac surgery. (2015) Papachristofi, O; Sharples, LD; Mackay, JH; Nashef, SAM; Fletcher, SN; Klein, AA; Association of Cardiothoracic Anaesthetists (ACTA)
  • Assessment of learning curves in complex surgical interventions: a consecutive case-series study. (2016) Papachristofi, Olympia; Jenkins, David; Sharples, Linda D
  • Does the "Weekend Effect" for Postoperative Mortality Stand Up to Scrutiny? Association for Cardiothoracic Anesthesia and Critical Care Cohort Study of 110,728 Cardiac Surgical Patients. (2018) Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick S; Sharples, Linda D; Association for Cardiothoracic Anaesthesia and Critical Care (AC
  • Effect of individual patient risk, centre, surgeon and anaesthetist on length of stay in hospital after cardiac surgery: Association of Cardiothoracic Anaesthesia and Critical Care (ACTACC) consecutive cases series study of 10 UK specialist centres. (2017) Papachristofi, Olympia; Klein, Andrew A; Mackay, John; Nashef, Samer; Fletcher, Nick; Sharples, Linda D; Association of Cardiothoracic Anaesthesia and Critical Care (ACT
  • Inequalities for women diagnosed with distal arch and descending thoracic aortic aneurysms: results from the Effective Treatments for Thoracic Aortic Aneurysms (ETTAA) cohort study. (2024) Pouncey, Anna L; Patel, Dhvni; Freeman, Carol; Sastry, Priya; Bicknell, Colin; Large, Stephen R; Sharples, Linda D
  • Impact of patient sex on selection for abdominal aortic aneurysm repair: a discrete choice experiment. (2025) Pouncey, Anna Louise; Loría-Rebolledo, Luis Enrique; Sharples, Linda; Bicknell, Colin; Ryan, Mandy; Powell, Janet picture_as_pdf
  • The ETTAA study protocol: a UK-wide observational study of 'Effective Treatments for Thoracic Aortic Aneurysm'. (2015) Sastry, Priya; Hughes, Victoria; Hayes, Paul; Vallabhaneni, Srinivasa; Sharples, Linda; Thompson, Matt; Catarino, Pedro; Moorjani, Narain; Vale, Luke; Gray, Joanne; Cook, Andrew; Elefteriades, John A; Large, Stephen R; ETTAA Collaborators
  • Time-varying Comparison of All-cause Mortality After Liver Transplantation Between Recipients With and Without Hepatocellular Carcinoma: A Population-based Cohort Study Using the United Kingdom Liver Transplant Registry. (2022) Sehjal, Jyoti; Sharples, Linda D; Keogh, Ruth H; Walker, Kate; Prachalias, Andreas; Heaton, Nigel; Ivanics, Tommy; van der Meulen, Jan; Wallace, David
  • A systematic review and meta-analysis estimating the population prevalence of comorbidities in children and adolescents aged 5 to 18 years. (2019) Sharma, Vishal; Coleman, Susanne; Nixon, Jane; Sharples, Linda; Hamilton-Shield, Julian; Rutter, Harry; Bryant, Maria
  • The role of statistics in the era of big data: Electronic health records for healthcare research. (2018) Sharples, Linda D
  • Longitudinal health-related quality of life in people with thoracic aortic aneurysms. (2024) Sharples, Linda D; Anagnostopoulou, Vasiliki; Pouncey, Anna L; Freeman, Carol; McCarthy, Andrew; Gray, Joanne; McMeekin, Peter; Sastry, Priya; Vale, Luke; Bicknell, Colin; Large, Stephen R
  • Meta-analysis of randomised controlled trials of oral mandibular advancement devices and continuous positive airway pressure for obstructive sleep apnoea-hypopnoea. (2015) Sharples, Linda D; Clutterbuck-James, Abigail L; Glover, Matthew J; Bennett, Maxine S; Chadwick, Rebecca; Pittman, Marcus A; Quinnell, Timothy G
  • Five-year results of Amaze: a randomized controlled trial of adjunct surgery for atrial fibrillation. (2022) Sharples, Linda D; Mills, Christine; Chiu, Yi-Da; Fynn, Simon; Holcombe, Helen M; Nashef, Samer AM
  • Amaze: a double-blind, multicentre randomised controlled trial to investigate the clinical effectiveness and cost-effectiveness of adding an ablation device-based maze procedure as an adjunct to routine cardiac surgery for patients with pre-existing atrial fibrillation. (2018) Sharples, Linda; Everett, Colin; Singh, Jeshika; Mills, Christine; Spyt, Tom; Abu-Omar, Yasir; Fynn, Simon; Thorpe, Benjamin; Stoneman, Victoria; Goddard, Hester; Fox-Rushby, Julia; Nashef, Samer
  • Exploring mechanisms of action in clinical trials of complex surgical interventions using mediation analysis. (2020) Sharples, Linda; Papachristofi, Olympia; Rex, Saleema; Landau, Sabine
  • Aneurysm growth, survival, and quality of life in untreated thoracic aortic aneurysms: the effective treatments for thoracic aortic aneurysms study. (2021) Sharples, Linda; Sastry, Priya; Freeman, Carol; Bicknell, Colin; Chiu, Yi Da; Vallabhaneni, Srinivasa Rao; Cook, Andrew; Gray, Joanne; McCarthy, Andrew; McMeekin, Peter; Vale, Luke; Large, Stephen
  • Endovascular stent grafting and open surgical replacement for chronic thoracic aortic aneurysms: a systematic review and prospective cohort study. (2021) Sharples, Linda; Sastry, Priya; Freeman, Carol; Gray, Joanne; McCarthy, Andrew; Chiu, Yi-Da; Bicknell, Colin; McMeekin, Peter; Vallabhaneni, S Rao; Cook, Andrew; Vale, Luke; Large, Stephen
  • Power and sample size for multistate model analysis of longitudinal discrete outcomes in disease prevention trials. (2020) Smith, Isabelle L; Nixon, Jane E; Sharples, Linda
  • Experiences of Structured Elicitation for Model-Based Cost-Effectiveness Analyses. (2018) Soares, Marta O; Sharples, Linda; Morton, Alec; Claxton, Karl; Bojke, Laura
  • Dynamic Prediction, Mediation and Communication for Survival Outcomes, with applications to Cystic Fibrosis. (2021) Tanner, KT
  • Mediation of the total effect of cystic fibrosis-related diabetes on mortality: A UK Cystic Fibrosis Registry cohort study. (2022) Tanner, Kamaryn T; Daniel, Rhian M; Bilton, Diana; Simmonds, Nicholas J; Sharples, Linda D; Keogh, Ruth H
  • Dynamic Survival Prediction Combining Landmarking with a Machine Learning Ensemble: Methodology and Empirical Comparison. (2020) Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H
  • Methods of analysis for survival outcomes with time-updated mediators, with application to longitudinal disease registry data. (2022) Tanner, Kamaryn T; Sharples, Linda D; Daniel, Rhian M; Keogh, Ruth H
  • Erratum to: Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. (2017) Thom, H; Jackson, C; Welton, N; Sharples, L
  • Using Parameter Constraints to Choose State Structures in Cost-Effectiveness Modelling. (2017) Thom, Howard; Jackson, Chris; Welton, Nicky; Sharples, Linda
  • Cost-effectiveness of initial stress cardiovascular MR, stress SPECT or stress echocardiography as a gate-keeper test, compared with upfront invasive coronary angiography in the investigation and management of patients with stable chest pain: mid-term outcomes from the CECaT randomised controlled trial. (2014) Thom, Howard; West, Nicholas EJ; Hughes, Vikki; Dyer, Matthew; Buxton, Martin; Sharples, Linda D; Jackson, Christopher H; Crean, Andrew M; CECaT study group
  • Methods for Handling Unobserved Covariates in a Bayesian Update of a Cost-effectiveness Model. (2017) Thorpe, Benjamin; Carroll, Orlagh; Sharples, Linda
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  • Admission Avoidance Hospital at Home: Extending understanding using trial and observational data. (2024) Edgar, K picture_as_pdf
  • Contrasting principal stratum and hypothetical strategy estimands in multi-period crossover trials with incomplete data. (2023) Matthews, John NS; Bazakou, Sofia; Henderson, Robin; Sharples, Linda D picture_as_pdf