Items where Author is "Stewart, LB"
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Number of items: 29.
2018
Duffy, CW;
Amambua-Ngwa, A;
Ahouidi, AD;
Diakite, M;
Awandare, GA;
Ba, H;
Tarr, SJ;
Murray, L;
Stewart, LB;
D'Alessandro, U;
+3 more...
Otto, TD;
Kwiatkowski, DP;
Conway, DJ;
(2018)
Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development.
Scientific reports, 8 (1).
p. 15763.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-018-34078-3
Lee, HJ;
Georgiadou, A;
Walther, M;
Nwakanma, D;
Stewart, LB;
Levin, M;
Otto, TD;
Conway, DJ;
Coin, LJ;
Cunnington, AJ;
(2018)
Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria.
Science translational medicine, 10 (447).
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.aar3619
Tsagris, DJ;
Birchall, K;
Bouloc, N;
Large, JM;
Merritt, A;
Smiljanic-Hurley, E;
Wheldon, M;
Ansell, KH;
Kettleborough, C;
Whalley, D;
+4 more...
Stewart, LB;
Bowyer, PW;
Baker, DA;
Osborne, SA;
(2018)
Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).
Bioorganic & medicinal chemistry letters.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2018.08.028
Item availability may be restricted.
2017
Baker, DA;
Stewart, LB;
Large, JM;
Bowyer, PW;
Ansell, KH;
Jiménez-Díaz, MB;
El Bakkouri, M;
Birchall, K;
Dechering, KJ;
Bouloc, NS;
+19 more...
Coombs, PJ;
Whalley, D;
Harding, DJ;
Smiljanic-Hurley, E;
Wheldon, MC;
Walker, EM;
Dessens, JT;
Lafuente, MJ;
Sanz, LM;
Gamo, FJ;
Ferrer, SB;
Hui, R;
Bousema, T;
Angulo-Barturén, I;
Merritt, AT;
Croft, SL;
Gutteridge, WE;
Kettleborough, CA;
Osborne, SA;
(2017)
A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission.
Nature communications, 8 (1).
p. 430.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-017-00572-x
Murray, L;
Stewart, LB;
Tarr, SJ;
Ahouidi, AD;
Diakite, M;
Amambua-Ngwa, A;
Conway, DJ;
(2017)
Multiplication rate variation in the human malaria parasite Plasmodium falciparum.
Scientific reports, 7 (1).
p. 6436.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-017-06295-9
2015
Bowyer, PW;
Stewart, LB;
Aspeling-Jones, H;
Mensah-Brown, HE;
Ahouidi, AD;
Amambua-Ngwa, A;
Awandare, GA;
Conway, DJ;
(2015)
Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different endemic populations.
Infection and immunity, 83 (6).
pp. 2575-82.
ISSN 0019-9567
DOI: https://doi.org/10.1128/IAI.03009-14
Full text not available from this repository.
Mensah-Brown, HE;
Amoako, N;
Abugri, J;
Stewart, LB;
Agongo, G;
Dickson, EK;
Ofori, MF;
Stoute, JA;
Conway, DJ;
Awandare, GA;
(2015)
Analysis of erythrocyte invasion mechanisms of Plasmodium falciparum clinical isolates across three endemic areas within one country.
The Journal of infectious diseases.
ISSN 0022-1899
DOI: https://doi.org/10.1093/infdis/jiv207
Full text not available from this repository.
2014
Pena, S;
Fagundez, C;
Medeiros, A;
Comini, M;
Scarone, L;
Sellanes, D;
Manta, E;
Tulla-Puche, J;
Albericio, F;
Stewart, L;
+2 more...
Yardleyh, V;
Serra, G;
(2014)
Synthesis of cyclohexapeptides as antimalarial and anti-trypanosomal agents.
MedChemComm, 5 (9).
pp. 1309-1316.
ISSN 2040-2503
DOI: https://doi.org/10.1039/c4md00135d
Full text not available from this repository.
Preston, MD;
Campino, S;
Assefa, SA;
Echeverry, DF;
Ocholla, H;
Amambua-Ngwa, A;
Stewart, LB;
Conway, DJ;
Borrmann, S;
Michon, P;
+12 more...
Zongo, I;
Ouédraogo, JB;
Djimde, AA;
Doumbo, OK;
Nosten, F;
Pain, A;
Bousema, T;
Drakeley, CJ;
Fairhurst, RM;
Sutherland, CJ;
Roper, C;
Clark, TG;
(2014)
A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains.
Nature communications, 5.
p. 4052.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms5052
Tewari, R;
Patzewitz, EM;
Poulin, B;
Stewart, L;
Baker, DA;
(2014)
Development of a Transgenic Plasmodium berghei Line (Pbpfpkg) Expressing the P. falciparum cGMP-Dependent Protein Kinase, a Novel Antimalarial Drug Target.
PloS one, 9 (5).
e96923.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0096923
2013
Booth, A;
Clarke, M;
Dooley, G;
Ghersi, D;
Moher, D;
Petticrew, M;
Stewart, L;
(2013)
PROSPERO at one year: an evaluation of its utility.
Systematic reviews, 2.
p. 4.
ISSN 2046-4053
DOI: https://doi.org/10.1186/2046-4053-2-4
2012
Amambua-Ngwa, A;
Tetteh, KK;
Manske, M;
Gomez-Escobar, N;
Stewart, LB;
Deerhake, ME;
Cheeseman, IH;
Newbold, CI;
Holder, AA;
Knuepfer, E;
+6 more...
Janha, O;
Jallow, M;
Campino, S;
Macinnis, B;
Kwiatkowski, DP;
Conway, DJ;
(2012)
Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.
PLoS genetics, 8 (11).
e1002992.
ISSN 1553-7390
DOI: https://doi.org/10.1371/journal.pgen.1002992
Peña, S;
Scarone, L;
Manta, E;
Stewart, L;
Yardley, V;
Croft, S;
Serra, G;
(2012)
Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity.
Bioorganic & medicinal chemistry letters, 22 (15).
pp. 4994-7.
ISSN 0960-894X
DOI: https://doi.org/10.1016/j.bmcl.2012.06.028
Full text not available from this repository.
2010
Ochola, LI;
Tetteh, KK;
Stewart, LB;
Riitho, V;
Marsh, K;
Conway, DJ;
(2010)
Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum.
Molecular biology and evolution, 27 (10).
pp. 2344-51.
ISSN 0737-4038
DOI: https://doi.org/10.1093/molbev/msq119
2009
Cheeseman, IH;
Gomez-Escobar, N;
Carret, CK;
Ivens, A;
Stewart, LB;
Tetteh, KK;
Conway, DJ;
(2009)
Gene copy number variation throughout the Plasmodium falciparum genome.
BMC genomics, 10.
p. 353.
ISSN 1471-2164
DOI: https://doi.org/10.1186/1471-2164-10-353
Stewart, L;
Gosling, R;
Griffin, J;
Gesase, S;
Campo, J;
Hashim, R;
Masika, P;
Mosha, J;
Bousema, T;
Shekalaghe, S;
+5 more...
Cook, J;
Corran, P;
Ghani, A;
Riley, EM;
Drakeley, C;
(2009)
Rapid assessment of malaria transmission using age-specific sero-conversion rates.
PloS one, 4 (6).
e6083.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0006083
Tetteh, KK;
Stewart, LB;
Ochola, LI;
Amambua-Ngwa, A;
Thomas, AW;
Marsh, K;
Weedall, GD;
Conway, DJ;
(2009)
Prospective Identification of Malaria Parasite Genes under Balancing Selection.
PloS one, 4 (5).
e5568.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0005568
Williams, GS;
Mweya, C;
Stewart, L;
Mtove, G;
Reyburn, H;
Cook, J;
Corran, PH;
Riley, EM;
Drakeley, CJ;
(2009)
Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity.
Malaria journal, 8.
p. 168.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-8-168
2008
Cheeseman, I;
Gomez-Escobar, N;
Carret, C;
Ivens, A;
Tetteh, K;
Stewart, L;
Conway, D;
(2008)
A genome-wide survey of gene amplifications and deletions in laboratory and field isolates of Plasmodium falciparam.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/7910
Full text not available from this repository.
Tetteh, K;
Ochola, L;
Stewart, L;
Ngwa, A;
Marsh, K;
Conway, D;
(2008)
Studies of natural selection on malaria parasite merozoites in relation to invasion and immunity.
[Conference or Workshop Item]
http://researchonline.lshtm.ac.uk/id/eprint/7909
Full text not available from this repository.
2007
Haynes, RK;
Wong, HN;
Lee, KW;
Lung, CM;
Shek, LY;
Williams, ID;
Croft, SL;
Vivas, L;
Rattray, L;
Stewart, L;
+2 more...
Wong, VK;
Ko, BC;
(2007)
Preparation of N-Sulfonyl- and N-Carbonyl-11-Azaartemisinins with Greatly Enhanced Thermal Stabilities: in vitro Antimalarial Activities.
ChemMedChem, 2 (10).
pp. 1464-1479.
ISSN 1860-7179
DOI: https://doi.org/10.1002/cmdc.200700065
Full text not available from this repository.
Vivas, L;
Rattray, L;
Stewart, L;
Bongard, E;
Robinson, BL;
Peters, W;
Croft, SL;
(2007)
Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo.
Acta tropica, 105 (3).
pp. 222-8.
ISSN 0001-706X
DOI: https://doi.org/10.1016/j.actatropica.2007.12.005
Full text not available from this repository.
Vivas, L;
Rattray, L;
Stewart, LB;
Robinson, BL;
Fugmann, B;
Haynes, RK;
Peters, W;
Croft, SL;
(2007)
Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo.
The Journal of antimicrobial chemotherapy, 59 (4).
pp. 658-665.
ISSN 0305-7453
DOI: https://doi.org/10.1093/jac/dkl563
Full text not available from this repository.
2006
Haynes, RK;
Fugmann, B;
Stetter, J;
Rieckmann, K;
Heilmann, HD;
Chan, HW;
Cheung, MK;
Lam, WL;
Wong, HN;
Croft, SL;
+16 more...
Vivas, L;
Rattray, L;
Stewart, L;
Peters, W;
Robinson, BL;
Edstein, MD;
Kotecka, B;
Kyle, DE;
Beckermann, B;
Gerisch, M;
Radtke, M;
Schmuck, G;
Steinke, W;
Wollborn, U;
Schmeer, K;
Römer, A;
(2006)
Artemisone--a highly active antimalarial drug of the artemisinin class.
Angewandte Chemie (International ed in English), 45 (13).
pp. 2082-8.
ISSN 1433-7851
DOI: https://doi.org/10.1002/anie.200503071
Full text not available from this repository.
2005
Neimark, H;
Peters, W;
Robinson, BL;
Stewart, LB;
(2005)
Phylogenetic analysis and description of Eperythrozoon coccoides, proposal to transfer to the genus Mycoplasma as Mycoplasma coccoides comb. nov. and Request for an Opinion.
International journal of systematic and evolutionary microbiology, 55 (Pt 3).
pp. 1385-91.
ISSN 1466-5026
DOI: https://doi.org/10.1099/ijs.0.63437-0
Full text not available from this repository.
Peters, W;
Stewart, LB;
Robinson, BL;
(2005)
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
Annals of tropical medicine and parasitology, 99 (5).
pp. 457-72.
ISSN 0003-4983
DOI: https://doi.org/10.1179/136485905X51274
Full text not available from this repository.
2004
Stewart, LB;
Peters, W;
Robinson, BL;
(2004)
The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate.
Annals of tropical medicine and parasitology, 98 (8).
pp. 763-83.
ISSN 0003-4983
DOI: https://doi.org/10.1179/136485913X13789813917625
Full text not available from this repository.
2003
Peters, W;
Stewart, LB;
Robinson, BL;
(2003)
The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines.
Annals of tropical medicine and parasitology, 97 (3).
pp. 221-36.
ISSN 0003-4983
DOI: https://doi.org/10.1179/000349803235001886
Full text not available from this repository.
2002
Peters, W;
Fleck, SL;
Robinson, BL;
Stewart, LB;
Jefford, CW;
(2002)
The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials.
Annals of tropical medicine and parasitology, 96 (6).
pp. 559-73.
ISSN 0003-4983
DOI: https://doi.org/10.1179/000349802125001744
Full text not available from this repository.