Addressing the unknowns of antimicrobial resistance: quantifying and mapping the drivers of burden.


Knight, GM; Costelloe, C; Murray, KA; Robotham, JV; Atun, R; Holmes, AH; (2017) Addressing the unknowns of antimicrobial resistance: quantifying and mapping the drivers of burden. Clinical infectious diseases. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/cix765

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Abstract

The global threat of antimicrobial resistance (AMR) has arisen through a network of complex interacting factors. Many different sources and transmission pathways contribute to the ever-growing burden of AMR in our clinical settings. The lack of data on these mechanisms and the relative importance of different factors causing the emergence and spread of AMR hampers our global efforts to effectively manage the risks. Importantly, we have little quantitative knowledge on the relative contributions of these sources and are likely to be targeting our interventions suboptimally as a result. Here we propose a systems mapping approach to address the urgent need for reliable and timely data in order to strengthen the response to AMR.

Item Type: Article
Faculty and Department: Faculty of Epidemiology and Population Health > Dept of Infectious Disease Epidemiology
Research Centre: Antimicrobial Resistance Centre (AMR)
PubMed ID: 29020246
URI: http://researchonline.lshtm.ac.uk/id/eprint/4645788

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