Hair mercury levels, fish consumption, and cognitive development in preschool children from Granada, Spain


Freire, C; Ramos, R; Lopez-Espinosa, MJ; Diez, S; Vioque, J; Ballester, F; Fernandez, MF; (2010) Hair mercury levels, fish consumption, and cognitive development in preschool children from Granada, Spain. Environmental research, 110 (1). pp. 96-104. ISSN 0013-9351 DOI: https://doi.org/10.1016/j.envres.2009.10.005

Full text not available from this repository.

Abstract

The main source of human exposure to mercury is the consumption of fish contaminated with methylmercury, which may adversely affect early neurodevelopment. This study assessed mercury levels in hair of preschoolers in Spain, where fish consumption is elevated, with the aim of investigating the influence of their fish intake and other factors on mercury exposure, and evaluating their association with cognitive development. A population-based birth cohort from Granada (Spain) was studied at the age of 4yr. Total mercury (T-Hg) levels were determined in children's hair, and daily fish intake was assessed by a food frequency questionnaire. The McCarthy Scales of Children's Abilities (MSCA) were used to assess children's motor and cognitive abilities. Complete data were gathered on 72 children, and multivariate analyses were performed to evaluate the influence of mercury exposure and fish intake on MSCA outcomes. Mean concentration of T-Hg in hair was 0.96 microg/g (95% confidence interval=0.76; 1.20 microg/g). T-Hg levels were associated with higher frequency of oily fish consumption, place of residence, maternal age, and passive smoking. After adjustment for fish intake, T-Hg levels > or =1microg/g were associated with decrements in the general cognitive (-6.6 points), memory (-8.4 points), and verbal (-7.5 points) MSCA scores. Higher mercury exposure in children from this Mediterranean area was associated with cognitive development delay. Studies on the putative benefits of fish intake during early development should consider mercury exposure from different fish species.

Item Type: Article
Keywords: Animals, Child Development/ drug effects, Child, Preschool, Cities, Cognition/ drug effects, Cohort Studies, Cross-Sectional Studies, Eating, Environmental Monitoring, Fishes, Hair/ chemistry, Humans, Mercury/analysis/pharmacokinetics/ toxicity, Methylmercury Compounds/analysis/pharmacokinetics/toxicity, Multivariate Analysis, Rural Population/statistics & numerical data, Spain, Urban Population/statistics & numerical data, Water Pollutants, Chemical/analysis/pharmacokinetics/ toxicity, Animals, Child Development, drug effects, Child, Preschool, Cities, Cognition, drug effects, Cohort Studies, Cross-Sectional Studies, Eating, Environmental Monitoring, Fishes, Hair, chemistry, Humans, Mercury, analysis, pharmacokinetics, toxicity, Methylmercury Compounds, analysis, pharmacokinetics, toxicity, Multivariate Analysis, Rural Population, statistics & numerical data, Spain, Urban Population, statistics & numerical data, Water Pollutants, Chemical, analysis, pharmacokinetics, toxicity
Faculty and Department: Faculty of Public Health and Policy > Dept of Social and Environmental Health Research
PubMed ID: 19909946
Web of Science ID: 273942000014
URI: http://researchonline.lshtm.ac.uk/id/eprint/2696

Statistics


Download activity - last 12 months
Downloads since deposit
0Downloads
347Hits
Accesses by country - last 12 months
Accesses by referrer - last 12 months
Impact and interest
Additional statistics for this record are available via IRStats2

Actions (login required)

Edit Item Edit Item