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Dessens, Johannes T; Tremp, Annie Z; Saeed, Sadia; (2021) Crystalloids: Fascinating Parasite Organelles Essential for Malaria Transmission. Trends in parasitology, 37 (7). pp. 581-584. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2021.04.002

Dickinson, Simon; Yi Chong, Huey; Leslie, Toby; Rowland, Mark; Schultz Hansen, Kristian; Boyers, Dwayne; (2021) Cost-effectiveness of point-of-care C-Reactive Protein test compared to current clinical practice as an intervention to improve antibiotic prescription in malaria-negative patients in Afghanistan. PloS one, 16 (11). e0258299-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0258299 Item availability may be restricted.

Dombrowski, Jamille Gregório; Barateiro, André; Peixoto, Erika Paula Machado; Barros, André Boler Cláudio da Silva; Souza, Rodrigo Medeiros de; Clark, Taane Gregory; Campino, Susana; Wrenger, Carsten; Wunderlich, Gerhard; Palmisano, Giuseppe; +3 more... Epiphanio, Sabrina; Gonçalves, Lígia Antunes; Marinho, Claudio Romero Farias; (2021) Adverse pregnancy outcomes are associated with Plasmodium vivax malaria in a prospective cohort of women from the Brazilian Amazon. PLoS neglected tropical diseases, 15 (4). e0009390-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0009390

Dosoo, David Kwame; Malm, Kezia; Oppong, Felix Boakye; Gyasi, Richard; Oduro, Abraham; Williams, John; Atibilla, Dorcas; Peprah, Nana Yaw; Twumasi, Mieks; Owusu-Agyei, Seth; +3 more... Greenwood, Brian; Chandramohan, Daniel; Asante, Kwaku Poku; (2021) Effectiveness of intermittent preventive treatment in pregnancy with sulphadoxine-pyrimethamine (IPTp-SP) in Ghana. BMJ global health, 6 (8). e005877-e005877. ISSN 2059-7908 DOI: https://doi.org/10.1136/bmjgh-2021-005877

Druetz, Thomas; Stresman, Gillian; Ashton, Ruth A; Joseph, Vena; van den Hoogen, Lotus; Worges, Matt; Hamre, Karen ES; Fayette, Carl; Monestime, Frank; Impoinvil, Daniel; +5 more... Rogier, Eric; Chang, Michelle A; Lemoine, Jean Frantz; Drakeley, Chris; Eisele, Thomas P; (2021) The Immediate Effects of a Combined Mass Drug Administration and Indoor Residual Spraying Campaign to Accelerate Progress Toward Malaria Elimination in Grande-Anse, Haiti. JOURNAL OF INFECTIOUS DISEASES, 225 (9). pp. 1611-1620. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiab259

de Souza, Dziedzom K; Thomas, Rebecca; Bradley, John; Leyrat, Clemence; Boakye, Daniel A; Okebe, Joseph; (2021) Ivermectin treatment in humans for reducing malaria transmission. Cochrane Database of Systematic Reviews, 6 (6). CD013117-. ISSN 1469-493X DOI: https://doi.org/10.1002/14651858.CD013117.pub2

de Wit, Mariken; Cairns, Matthew; Compaoré, Yves Daniel; Sagara, Issaka; Kuepfer, Irene; Zongo, Issaka; Barry, Amadou; Diarra, Modibo; Tapily, Amadou; Coumare, Samba; +9 more... Thera, Ismaila; Nikiema, Frederic; Yerbanga, R Serge; Guissou, Rosemonde M; Tinto, Halidou; Dicko, Alassane; Chandramohan, Daniel; Greenwood, Brian; Ouedraogo, Jean Bosco; (2021) Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria. Malaria journal, 20 (1). 274-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03802-2

Edwards, Hannah M; Dixon, Ruth; Zegers de Beyl, Celine; Celhay, Olivier; Rahman, Mousumi; Myint Oo, Moe; Lwin, Thandar; Lin, Zaw; San, Thiri; Thwe Han, Kay; +10 more... Myaing Nyunt, Myaing; Plowe, Christopher; Stresman, Gillian; Hall, Tom; Drakeley, Chris; Hamade, Prudence; Aryal, Siddhi; Roca-Feltrer, Arantxa; Hlaing, Thaung; Thi, Aung; (2021) Prevalence and seroprevalence of Plasmodium infection in Myanmar reveals highly heterogeneous transmission and a large hidden reservoir of infection. PloS one, 16 (6). e0252957-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0252957

Ekusai-Sebatta, Deborah; Arinaitwe, Emmanuel; Mpimbaza, Arthur; Nankabirwa, Joaniter I; Drakeley, Chris; Rosenthal, Philip J; Staedke, Sarah G; Muyinda, Herbert; (2021) Challenges and opportunities for use of long-lasting insecticidal nets to prevent malaria during overnight travel in Uganda: a qualitative study. Malaria journal, 20 (1). 283-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03811-1

Ellis, Katherine M; Lucantoni, Leonardo; Chavchich, Marina; Abraham, Matthew; De Paoli, Amanda; Luth, Madeline R; Zeeman, Anne-Marie; Delves, Michael J; Terán, Fernando Sánchez-Román; Straschil, Ursula; +8 more... Baum, Jake; Kocken, Clemens HM; Ralph, Stuart A; Winzeler, Elizabeth A; Avery, Vicky M; Edstein, Michael D; Baell, Jonathan B; Creek, Darren J; (2021) The Novel bis-1,2,4-Triazine MIPS-0004373 Demonstrates Rapid and Potent Activity against All Blood Stages of the Malaria Parasite. Antimicrobial Agents and Chemotherapy, 65 (11). e0031121-. ISSN 0066-4804 DOI: https://doi.org/10.1128/AAC.00311-21

Elmardi, Khalid Abdelmutalab; Adam, Ishag; Malik, Elfatih Mohammed; Kafy, Hmooda Toto; Abdin, Mogahid Sheikheldien; Kleinschmidt, Immo; Kremers, Stef; (2021) Impact of malaria control interventions on malaria infection and anaemia in areas with irrigated schemes: a cross-sectional population-based study in Sudan. BMC infectious diseases, 21 (1). 1248-. ISSN 1471-2334 DOI: https://doi.org/10.1186/s12879-021-06929-4

Fornace, Kimberly M; Diaz, Adriana V; Lines, Jo; Drakeley, Chris J; (2021) Achieving global malaria eradication in changing landscapes. Malaria journal, 20 (1). 69-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03599-0

Gibbins, Matthew P; Müller, Katja; Matuschewski, Kai; Silvie, Olivier; Hafalla, Julius Clemence R; (2021) Inferior T cell immunogenicity of a Plasmodium berghei model liver stage antigen expressed throughout pre-erythrocytic maturation. Parasite Immunology, 43 (12). e12877-. ISSN 0141-9838 DOI: https://doi.org/10.1111/pim.12877

Gilmartin, Colin; Nonvignon, Justice; Cairns, Matthew; Milligan, Paul; Bocoum, Fadima; Winskill, Peter; Moroso, Diego; Collins, David; (2021) Seasonal malaria chemoprevention in the Sahel subregion of Africa: a cost-effectiveness and cost-savings analysis. The Lancet Global Health, 9 (2). e199-e208. DOI: https://doi.org/10.1016/S2214-109X(20)30475-7

Greenwood, Brian; Cairns, Matthew; Chaponda, Mike; Chico, R Matthew; Dicko, Alassane; Ouedraogo, Jean-Bosco; Phiri, Kamija S; Ter Kuile, Feiko O; Chandramohan, Daniel; (2021) Combining malaria vaccination with chemoprevention: a promising new approach to malaria control. Malaria journal, 20 (1). 361-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03888-8

Grignard, Lynn; Nolder, Debbie; Sepulveda, Nuno; Berhane, Araia; Mihreteab, Selam; Kaaya, Robert; Phelan, Jody; Moser, Kara; van Schalkwyk, Donelly A; Campino, Susana; +7 more... Parr, Jonathan B; Juliano, Jonathan J; Chiodini, Peter; Cunningham, Jane; Sutherland, Colin J; Drakeley, Chris; Beshir, Khalid B; (2021) Corrigendum to 'A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections'. EBioMedicine, 65. 103261-. ISSN 2352-3964 DOI: https://doi.org/10.1016/j.ebiom.2021.103261

Gupta, Himanshu; Sahu, Praveen K; Pattnaik, Rajyabardhan; Mohanty, Anita; Majhi, Megharay; Mohanty, Akshaya K; Pirpamer, Lukas; Hoffmann, Angelika; Mohanty, Sanjib; Wassmer, Samuel C; (2021) Plasma levels of hsa-miR-3158-3p microRNA on admission correlate with MRI findings and predict outcome in cerebral malaria. Clinical and Translational Medicine, 11 (6). e396-. ISSN 2001-1326 DOI: https://doi.org/10.1002/ctm2.396

Gupta, Himanshu; Wassmer, Samuel C; (2021) Harnessing the Potential of miRNAs in Malaria Diagnostic and Prevention. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 11. 793954-. ISSN 2235-2988 DOI: https://doi.org/10.3389/fcimb.2021.793954

Gutman, Julie R; Khairallah, Carole; Stepniewska, Kasia; Tagbor, Harry; Madanitsa, Mwayiwawo; Cairns, Matthew; L'lanziva, Anne Joan; Kalilani, Linda; Otieno, Kephas; Mwapasa, Victor; +7 more... Meshnick, Steve; Kariuki, Simon; Chandramohan, Daniel; Desai, Meghna; Taylor, Steve M; Greenwood, Brian; Ter Kuile, Feiko O; (2021) Intermittent screening and treatment with artemisinin-combination therapy versus intermittent preventive treatment with sulphadoxine-pyrimethamine for malaria in pregnancy: a systematic review and individual participant data meta-analysis of randomised clinical trials. EClinicalMedicine, 41. 101160-. ISSN 2589-5370 DOI: https://doi.org/10.1016/j.eclinm.2021.101160

Gyaase, Stephaney; Asante, Kwaku Poku; Adeniji, Elisha; Boahen, Owusu; Cairns, Matthew; Owusu-Agyei, Seth; (2021) Potential effect modification of RTS,S/AS01 malaria vaccine efficacy by household socio-economic status. BMC public health, 21 (1). 240-. ISSN 1471-2458 DOI: https://doi.org/10.1186/s12889-021-10294-x

Hailemeskel, Elifaged; Tebeje, Surafel K; Behaksra, Sinknesh W; Shumie, Girma; Shitaye, Getasew; Keffale, Migbaru; Chali, Wakweya; Gashaw, Abrham; Ashine, Temesgen; Drakeley, Chris; +3 more... Bousema, Teun; Gadisa, Endalamaw; Tadesse, Fitsum G; (2021) The epidemiology and detectability of asymptomatic plasmodium vivax and plasmodium falciparum infections in low, moderate and high transmission settings in Ethiopia. Malaria journal, 20 (1). 59-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03587-4

Hema-Ouangraoua, Soumeya; Tranchot-Diallo, Juliette; Zongo, Issaka; Kabore, Nongodo Firmin; Nikièma, Frédéric; Yerbanga, Rakiswende Serge; Tinto, Halidou; Chandramohan, Daniel; Ouedraogo, Georges-Anicet; Greenwood, Brian; +1 more... Ouedraogo, Jean-Bosco; (2021) Impact of mass administration of azithromycin as a preventive treatment on the prevalence and resistance of nasopharyngeal carriage of Staphylococcus aureus. PloS one, 16 (10). e0257190-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0257190

Hon, Calvin; Friesen, Johannes; Ingmundson, Alyssa; Scheppan, Diana; Hafalla, Julius CR; Müller, Katja; Matuschewski, Kai; (2021) Conservation of S20 as an Ineffective and Disposable IFNγ-Inducing Determinant of Plasmodium Sporozoites Indicates Diversion of Cellular Immunity. Frontiers in microbiology, 12. 703804-. ISSN 1664-302X DOI: https://doi.org/10.3389/fmicb.2021.703804

Hoyt, Jenna; Hill, Jenny; Achieng, Florence; Ouma, Peter; Kariuki, Simon; Desai, Meghna; Webster, Jayne; (2021) Healthcare provider and pregnant women's perspectives on the implementation of intermittent screening and treatment with dihydroartemisinin-piperaquine for malaria in pregnancy in western Kenya: a qualitative study. MALARIA JOURNAL, 20 (1). 291-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03826-8

Hutchinson, Eleanor; Mundua, Sunday; Ochero, Lydia; Mbonye, Anthony; Clarke, Sian E; (2021) Life in the buffer zone: Social relations and surplus health workers in Uganda's medicines retail sector. Social Science and Medicine, 300. 113941-. DOI: https://doi.org/10.1016/j.socscimed.2021.113941

Hutchinson, Eleanor; Nayiga, Susan; Nabirye, Christine; Taaka, Lilian; Westercamp, Nelli; Rowe, Alexander K; Staedke, Sarah G; (2021) Opening the 'black box' of collaborative improvement: a qualitative evaluation of a pilot intervention to improve quality of malaria surveillance data in public health centres in Uganda. Malaria journal, 20 (1). 289-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03805-z

Ishola, David; Manno, Daniela; Afolabi, Muhammed O; Keshinro, Babajide; Bockstal, Viki; Rogers, Baimba; Owusu-Kyei, Kwabena; Serry-Bangura, Alimamy; Swaray, Ibrahim; Lowe, Brett; +25 more... Kowuor, Dickens; Baiden, Frank; Mooney, Thomas; Smout, Elizabeth; Köhn, Brian; Otieno, Godfrey T; Jusu, Morrison; Foster, Julie; Samai, Mohamed; Deen, Gibrilla Fadlu; Larson, Heidi; Lees, Shelley; Goldstein, Neil; Gallagher, Katherine E; Gaddah, Auguste; Heerwegh, Dirk; Callendret, Benoit; Luhn, Kerstin; Robinson, Cynthia; Leyssen, Maarten; Greenwood, Brian; Douoguih, Macaya; Leigh, Bailah; Watson-Jones, Deborah; EBL3001 study group; (2021) Safety and long-term immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in adults in Sierra Leone: a combined open-label, non-randomised stage 1, and a randomised, double-blind, controlled stage 2 trial. Lancet Infectious Diseases, 22 (1). pp. 97-109. ISSN 1473-3099 DOI: https://doi.org/10.1016/S1473-3099(21)00125-0

Jatta, Ebrima; Carrasco-Tenezaca, Majo; Jawara, Musa; Bradley, John; Ceesay, Sainey; D'Alessandro, Umberto; Jeffries, David; Kandeh, Balla; Lee, Daniel Sang-Hoon; Pinder, Margaret; +3 more... Wilson, Anne L; Knudsen, Jakob; Lindsay, Steve W; (2021) Impact of increased ventilation on indoor temperature and malaria mosquito density: an experimental study in The Gambia. Journal of the Royal Society, Interface, 18 (178). 20201030-. ISSN 1742-5689 DOI: https://doi.org/10.1098/rsif.2020.1030 Item availability may be restricted.

Jeffries, Claire L; Cansado-Utrilla, Cintia; Beavogui, Abdoul H; Stica, Caleb; Lama, Eugene K; Kristan, Mojca; Irish, Seth R; Walker, Thomas; (2021) Evidence for natural hybridization and novel Wolbachia strain superinfections in the Anopheles gambiae complex from Guinea. Royal Society Open Science, 8 (4). 202032-. DOI: https://doi.org/10.1098/rsos.202032

Kamaliddin, Claire; Sutherland, Colin J; Houze, Sandrine; Cottrell, Gilles; Briand, Valerie; Castaneda Mogollon, Daniel; Pillai, Dylan R; (2021) The Role of Ultrasensitive Molecular Methods for Detecting Malaria-The Broader Perspective. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 73 (6). e1387-e1390. ISSN 1058-4838 DOI: https://doi.org/10.1093/cid/ciab221

Kaur, Harparkash; Allan, Elizabeth Louise; Eggelte, Teunis A; García, Guillermo A; Monti, Feliciano; (2021) A colorimetric test for the evaluation of the insecticide content of LLINs used on Bioko Island, Equatorial Guinea. Malaria Journal, 20 (1). 433-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-021-03967-w

Khalife, Jamal; Fréville, Aline; Gnangnon, Bénédicte; Pierrot, Christine; (2021) The Multifaceted Role of Protein Phosphatase 1 in Plasmodium. Trends in Parasitology, 37 (2). pp. 154-164. ISSN 1471-4922 DOI: https://doi.org/10.1016/j.pt.2020.09.003

Koopman, Jan Pieter R; Lule, Swaib A; Zziwa, Christopher; Akurut, Hellen; Lubyayi, Lawrence; Nampijja, Margaret; Akello, Florence; Balungi, Priscilla; Tumusiime, Josephine; Oduru, Gloria; +3 more... Elliott, Alison M; Webb, Emily L; Bradley, John; (2021) The determinants of lipid profiles in early adolescence in a Ugandan birth cohort. Scientific reports, 11 (1). 16503-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-021-96035-x

Kordes, Maximilian; Ormond, Louise; Rausch, Sebastian; Matuschewski, Kai; Hafalla, Julius Clemence R; (2021) TLR9 signalling inhibits Plasmodium liver infection by macrophage activation. Eur J Immunol, 52 (2). pp. 270-284. ISSN 0014-2980 DOI: https://doi.org/10.1002/eji.202149224

Kositz, Christian; Bradley, John; Hutchins, Harry; Last, Anna; D'Alessandro, Umberto; Marks, Michael; (2021) Broadening the range of use cases for ivermectin - a review of the evidence. Transactions of the Royal Society of Tropical Medicine and Hygiene, 116 (3). pp. 201-212. ISSN 0035-9203 DOI: https://doi.org/10.1093/trstmh/trab114

Krezanoski, Paul J; Roh, Michelle E; Rek, John; Nankabirwa, Joaniter I; Arinaitwe, Emmanuel; Staedke, Sarah G; Nayiga, Susan; Hsiang, Michelle S; Smith, David; Kamya, Moses; +1 more... Dorsey, Grant; (2021) Marked reduction in antibiotic usage following intensive malaria control in a cohort of Ugandan children. BMC medicine, 19 (1). 294-. ISSN 1741-7015 DOI: https://doi.org/10.1186/s12916-021-02167-2

Kwon, Hyeogsun; Simões, Maria L; Reynolds, Rebekah A; Dimopoulos, George; Smith, Ryan C; (2021) Additional Feeding Reveals Differences in Immune Recognition and Growth of Plasmodium Parasites in the Mosquito Host. mSphere, 6 (2). pp. 1-14. ISSN 2379-5042 DOI: https://doi.org/10.1128/mSphere.00136-21

Lidumniece, Elina; Withers-Martinez, Chrislaine; Hackett, Fiona; Collins, Christine R; Perrin, Abigail J; Koussis, Konstantinos; Bisson, Claudine; Blackman, Michael J; Jirgensons, Aigars; (2021) Peptidic boronic acids are potent cell-permeable inhibitors of the malaria parasite egress serine protease SUB1. Proceedings of the National Academy of Sciences of the United States of America, 118 (20). e2022696118-e2022696118. ISSN 0027-8424 DOI: https://doi.org/10.1073/pnas.2022696118

Lindsay, Steve W; Thomas, Matthew B; Kleinschmidt, Immo; (2021) Threats to the effectiveness of insecticide-treated bednets for malaria control: thinking beyond insecticide resistance. The Lancet. Global health, 9 (9). e1325-e1331. ISSN 2214-109X DOI: https://doi.org/10.1016/S2214-109X(21)00216-3

Lindsay, Steven W; Davies, Michael; Alabaster, Graham; Altamirano, Hector; Jatta, Ebrima; Jawara, Musa; Carrasco-Tenezaca, Majo; von Seidlein, Lorenz; Shenton, Fiona C; Tusting, Lucy S; +2 more... Wilson, Anne L; Knudsen, Jakob; (2021) Recommendations for building out mosquito-transmitted diseases in sub-Saharan Africa: the DELIVER mnemonic. Philosophical Transactions of the Royal Society B: Biological Sciences, 376 (1818). 20190814-. ISSN 0962-8436 DOI: https://doi.org/10.1098/rstb.2019.0814

Loua, Kovana Marcel; Milligan, Paul; (2021) Seasonal Malaria Chemoprevention in Guinea in 2020: coverage survey results. Technical Report. London School of Hygiene & Tropical Medicine, London and Universite Gamal Abdel Nasser, Conakry. DOI: https://doi.org/10.17037/PUBS.04663123

Lubyayi, Lawrence; Mpairwe, Harriet; Nkurunungi, Gyaviira; Lule, Swaib A; Nalwoga, Angela; Webb, Emily L; Levin, Jonathan; Elliott, Alison M; (2021) Infection-exposure in infancy is associated with reduced allergy-related disease in later childhood in a Ugandan cohort. eLife, 10. e66022-. ISSN 2050-084X DOI: https://doi.org/10.7554/eLife.66022

Ma, Xiangmei; Milligan, Paul; Lam, Kwok Fai; Cheung, Yin Bun; (2021) Ratio estimators of intervention effects on event rates in cluster randomized trials. Statistics in medicine, 41 (1). pp. 128-145. ISSN 0277-6715 DOI: https://doi.org/10.1002/sim.9226

Mahamar, Almahamoudou; Issiaka, Djibrilla; Youssouf, Ahamadou; Niambele, Sidi M; Soumare, Harouna M; Attaher, Oumar; Barry, Amadou; Narum, David L; Duffy, Patrick E; Greenwood, Brian; +2 more... Fried, Michal; Dicko, Alassane; (2021) Effect of 4 years of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali. Malaria journal, 20 (1). 23-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-020-03542-9

Mahamar, Almahamoudou; Lanke, Kjerstin; Graumans, Wouter; Diawara, Halimatou; Sanogo, Koualy; Diarra, Kalifa; Niambele, Sidi Mohamed; Gosling, Roly; Drakeley, Chris; Chen, Ingrid; +3 more... Dicko, Alassane; Bousema, Teun; Roh, Michelle E; (2021) Persistence of mRNA indicative of Plasmodium falciparum ring-stage parasites 42 days after artemisinin and non-artemisinin combination therapy in naturally infected Malians. Malaria journal, 20 (1). 34-. ISSN 1475-2875 DOI: https://doi.org/10.1186/s12936-020-03576-z

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Yovogan, Boulais; Sovi, Arthur; Padonou, Gil G; Adoha, Constantin J; Akinro, Bruno; Chitou, Saïd; Accrombessi, Manfred; Dangbénon, Edouard; Akpovi, Hilaire; Messenger, Louisa A; +8 more... Ossè, Razaki; Hounto, Aurore Ogouyemi; Cook, Jackie; Kleinschmidt, Immo; Ngufor, Corine; Rowland, Mark; Protopopoff, Natacha; Akogbéto, Martin C; (2021) Pre-intervention characteristics of the mosquito species in Benin in preparation for a randomized controlled trial assessing the efficacy of dual active-ingredient long-lasting insecticidal nets for controlling insecticide-resistant malaria vectors. PloS one, 16 (5). e0251742-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0251742