Items where Faculty or Department is "Dept of Pathogen Molecular Biology (-2019)"

LSHTM Organisational Structure (63214)

Faculty of Infectious and Tropical Diseases (20188)

Department of Infection Biology (6058)

Dept of Pathogen Molecular Biology (-2019) (1083) Month Authors/Creators Item Type Full Text

Article

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum. (2018) Tarr, Sarah J; Díaz-Ingelmo, Ofelia; Stewart, Lindsay B; Hocking, Suzanne E; Murray, Lee; Duffy, Craig W; Otto, Thomas D; Chappell, Lia; Rayner, Julian C; Awandare, Gordon A; Conway, David J

Genomic Surveillance of Enterococcus faecium Reveals Limited Sharing of Strains and Resistance Genes between Livestock and Humans in the United Kingdom. (2018) Gouliouris, Theodore; Raven, Kathy E; Ludden, Catherine; Blane, Beth; Corander, Jukka; Horner, Carolyne S; Hernandez-Garcia, Juan; Wood, Paul; Hadjirin, Nazreen F; Radakovic, Milorad; Holmes, Mark A; de Goffau, Marcus; Brown, Nicholas M; Parkhill, Julian; Peacock, Sharon J

Correction to: Detecting eukaryotic microbiota with single-cell sensitivity in human tissue. (2018) Lager, Susanne; de Goffau, Marcus C; Sovio, Ulla; Peacock, Sharon J; Parkhill, Julian; Stephen Charnock-Jones, D; Smith, Gordon CS

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development. (2018) Duffy, Craig W; Amambua-Ngwa, Alfred; Ahouidi, Ambroise D; Diakite, Mahamadou; Awandare, Gordon A; Ba, Hampate; Tarr, Sarah J; Murray, Lee; Stewart, Lindsay B; D'Alessandro, Umberto; Otto, Thomas D; Kwiatkowski, Dominic P; Conway, David J

Harnessing alternative sources of antimicrobial resistance data to support surveillance in low-resource settings. (2018) Ashley, Elizabeth A; Shetty, Nandini; Patel, Jean; van Doorn, Rogier; Limmathurotsakul, Direk; Feasey, Nicholas A; Okeke, Iruka N; Peacock, Sharon J

Prospective genomic surveillance of methicillin-resistant Staphylococcus aureus (MRSA) associated with bloodstream infection, England, 1 October 2012 to 30 September 2013. (2018) Toleman, Michelle S; Reuter, Sandra; Jamrozy, Dorota; Wilson, Hayley J; Blane, Beth; Harrison, Ewan M; Coll, Francesc; Hope, Russell J; Kearns, Angela; Parkhill, Julian; Peacock, Sharon J; Török, M Estée

Nasal carriage of Staphylococcus pseudintermedius in patients with granulomatosis with polyangiitis. (2018) Kronbichler, Andreas; Blane, Beth; Holmes, Mark A; Wagner, Josef; Parkhill, Julian; Peacock, Sharon J; Jayne, David RW; Harrison, Ewan M

An expanded global inventory of allelic variation in the most extremely polymorphic region of Plasmodium falciparum merozoite surface protein 1 provided by short read sequence data. (2018) Aspeling-Jones, Harvey; Conway, David J

The Role of Maternally Acquired Antibody in Providing Protective Immunity Against Nontyphoidal Salmonella in Urban Vietnamese Infants: A Birth Cohort Study. (2018) de Alwis, Ruklanthi; Tu, Le Thi Phuong; Quynh, Nhi Le Thi; Thompson, Corinne N; Anders, Katherine L; Van Thuy, Nguyen Thi; Hieu, Nguyen Trong; Vi, Lu Lan; Chau, Nguyen Van Vinh; Duong, Vu Thuy; Chau, Tran Thi Hong; Tuyen, Ha Thanh; Nga, Tran Vu Thieu; Minh, Pham Van; Tan, Trinh Van; Thu, Trang Nguyen Hoang; Nhu, Tran Do Hoang; Thwaites, Guy E; Simmons, Cameron; Baker, Stephen

Detecting eukaryotic microbiota with single-cell sensitivity in human tissue. (2018) Lager, Susanne; de Goffau, Marcus C; Sovio, Ulla; Peacock, Sharon J; Parkhill, Julian; Charnock-Jones, D Stephen; Smith, Gordon CS

PrimedRPA: primer design for recombinase polymerase amplification assays. (2018) Higgins, Matthew; Ravenhall, Matt; Ward, Daniel; Phelan, Jody; Ibrahim, Amy; Forrest, Matthew S; Clark, Taane G; Campino, Susana

Identifying mixed Mycobacterium tuberculosis infections from whole genome sequence data. (2018) Sobkowiak, Benjamin; Glynn, Judith R; Houben, Rein MGJ; Mallard, Kim; Phelan, Jody E; Guerra-Assunção, José Afonso; Banda, Louis; Mzembe, Themba; Viveiros, Miguel; McNerney, Ruth; Parkhill, Julian; Crampin, Amelia C; Clark, Taane G

Reply to Dookie et al., "Whole-Genome Sequencing To Guide the Selection of Treatment for Drug-Resistant Tuberculosis". (2018) Köser, Claudio U; Heyckendorf, Jan; Andres, Sönke; Olaru, Ioana D; Schön, Thomas; Sturegård, Erik; Beckert, Patrick; Schleusener, Viola; Kohl, Thomas A; Hillemann, Doris; Moradigaravand, Danesh; Parkhill, Julian; Peacock, Sharon J; Niemann, Stefan; Lange, Christoph; Merker, Matthias

Naturally occurring polymorphisms in the virulence regulator Rsp modulate Staphylococcus aureus survival in blood and antibiotic susceptibility. (2018) Krishna, Aishwarya; Holden, Matthew TG; Peacock, Sharon J; Edwards, Andrew M; Wigneshweraraj, Sivaramesh

Changing the paradigm for hospital outbreak detection by leading with genomic surveillance of nosocomial pathogens. (2018) Peacock, Sharon J; Parkhill, Julian; Brown, Nicholas M

Gene exchange drives the ecological success of a multi-host bacterial pathogen. (2018) Richardson, Emily J; Bacigalupe, Rodrigo; Harrison, Ewan M; Weinert, Lucy A; Lycett, Samantha; Vrieling, Manouk; Robb, Kirsty; Hoskisson, Paul A; Holden, Matthew TG; Feil, Edward J; Paterson, Gavin K; Tong, Steven YC; Shittu, Adebayo; van Wamel, Willem; Aanensen, David M; Parkhill, Julian; Peacock, Sharon J; Corander, Jukka; Holmes, Mark; Fitzgerald, J Ross

Emergence and rapid global dissemination of CTX-M-15-associated Klebsiella pneumoniae strain ST307. (2018) Wyres, Kelly L; Hawkey, Jane; Hetland, Marit AK; Fostervold, Aasmund; Wick, Ryan R; Judd, Louise M; Hamidian, Mohammad; Howden, Benjamin P; Löhr, Iren H; Holt, Kathryn E

RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics. (2018) Claessens, Antoine; Harris, Lynne M; Stanojcic, Slavica; Chappell, Lia; Stanton, Adam; Kuk, Nada; Veneziano-Broccia, Pamela; Sterkers, Yvon; Rayner, Julian C; Merrick, Catherine J

Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18. (2018) Cook, Sarah; Malyutina, Sofia; Kudryavtsev, Alexander; Averina, Maria; Bobrova, Natalia; Boytsov, Sergey; Brage, Soren; Clark, Taane; Diez Benavente, Ernest; Eggen, Anne Elise; Hopstock, Laila; Hughes, Alun; Johansen, Heidi; Kholmatova, Kamila; Kichigina, Anastasiya; Kontsevaya, Anna; Kornev, Michael; Leong, Darryl; Magnus, Per; Mathiesen, Ellisiv; McKee, Martin; Morgan, Katy; Nilssen, Odd; Plakhov, Ilya; Quint, Jennifer; Rapala, Alicja; Ryabikov, Andrey; Saburova, Lyudmila; Schirmer, Henrik; Shapkina, Marina; Shiekh, Suhail; Shkolnikov, Vladimir; Stylidis, Michael; Voevoda, Michael; Westgate, Kate; Leon, David

Effect of temperature on Burkholderia pseudomallei growth, proteomic changes, motility and resistance to stress environments. (2018) Paksanont, Suporn; Sintiprungrat, Kitisak; Yimthin, Thatcha; Pumirat, Pornpan; Peacock, Sharon J; Chantratita, Narisara

Know Your Heart: Rationale, design and conduct of a cross-sectional study of cardiovascular structure, function and risk factors in 4500 men and women aged 35-69 years from two Russian cities, 2015-18. (2018) Cook, Sarah; Malyutina, Sofia; Kudryavtsev, Alexander V; Averina, Maria; Bobrova, Natalia; Boytsov, Sergey; Brage, Soren; Clark, Taane G; Diez Benavente, Ernest; Eggen, Anne Elise; Hopstock, Laila A; Hughes, Alun; Johansen, Heidi; Kholmatova, Kamila; Kichigina, Anastasiya; Kontsevaya, Anna; Kornev, Michael; Leong, Darryl; Magnus, Per; Mathiesen, Ellisiv; McKee, Martin; Morgan, Katy; Nilssen, Odd; Plakhov, Ilya; Quint, Jennifer K; Rapala, Alicja; Ryabikov, Andrey; Saburova, Lyudmila; Schirmer, Henrik; Shapkina, Marina; Shiekh, Suhail; Shkolnikov, Vladimir M; Stylidis, Michael; Voevoda, Michael; Westgate, Kate; Leon, David A

Genomic insights into the emergence and spread of antimicrobial-resistant bacterial pathogens. (2018) Baker, Stephen; Thomson, Nicholas; Weill, François-Xavier; Holt, Kathryn E

Vibrio cholerae accessory colonisation factor AcfC: a chemotactic protein with a role in hyperinfectivity. (2018) Valiente, Esmeralda; Davies, Cadi; Mills, Dominic C; Getino, Maria; Ritchie, Jennifer M; Wren, Brendan W

Surveillance and Epidemiology of Drug Resistant Infections Consortium (SEDRIC): Supporting the transition from strategy to action. (2018) Fukuda, Keiji; Limmathurotsakul, Direk; Okeke, Iruka N; Shetty, Nandini; van Doorn, Rogier; Feasey, Nicholas A; Chiara, Francesca; Zoubiane, Ghada; Jinks, Tim; Parkhill, Julian; Patel, Jean; Reid, Stuart WJ; Holmes, Alison H; Peacock, Sharon J; Surveillance and Epidemiology of Drug Resistant Infections Conso

Are commercial providers a viable option for clinical bacterial sequencing? (2018) Raven, Kathy; Blane, Beth; Churcher, Carol; Parkhill, Julian; Peacock, Sharon J

Structure-activity relationships in a new class of non-substrate-like covalent inhibitors of the bacterial glycosyltransferase LgtC. (2018) Xu, Yong; Cuccui, Jon; Denman, Carmen; Maharjan, Tripty; Wren, Brendan W; Wagner, Gerd K

Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis. (2018) Baddam, Ramani; Kumar, Narender; Wieler, Lothar H; Lankapalli, Aditya Kumar; Ahmed, Niyaz; Peacock, Sharon J; Semmler, Torsten

Detection and Characterization of Homologues of Human Hepatitis Viruses and Pegiviruses in Rodents and Bats in Vietnam. (2018) Van Nguyen, Dung; Van Nguyen, Cuong; Bonsall, David; Ngo, Tue Tri; Carrique-Mas, Juan; Pham, Anh Hong; Bryant, Juliet E; Thwaites, Guy; Baker, Stephen; Woolhouse, Mark; Simmonds, Peter

Emergence of an Extensively Drug-Resistant Salmonella enterica Serovar Typhi Clone Harboring a Promiscuous Plasmid Encoding Resistance to Fluoroquinolones and Third-Generation Cephalosporins. (2018) Klemm, Elizabeth J; Shakoor, Sadia; Page, Andrew J; Qamar, Farah Naz; Judge, Kim; Saeed, Dania K; Wong, Vanessa K; Dallman, Timothy J; Nair, Satheesh; Baker, Stephen; Shaheen, Ghazala; Qureshi, Shahida; Yousafzai, Mohammad Tahir; Saleem, Muhammad Khalid; Hasan, Zahra; Dougan, Gordon; Hasan, Rumina

Duration of exposure to multiple antibiotics is associated with increased risk of VRE bacteraemia: a nested case-control study. (2018) Gouliouris, Theodore; Warne, Ben; Cartwright, Edward JP; Bedford, Luke; Weerasuriya, Chathika K; Raven, Kathy E; Brown, Nick M; Török, M Estée; Limmathurotsakul, Direk; Peacock, Sharon J

Melioidosis. (2018) Wiersinga, W Joost; Virk, Harjeet S; Torres, Alfredo G; Currie, Bart J; Peacock, Sharon J; Dance, David AB; Limmathurotsakul, Direk

Retrospective analysis assessing the spatial and temporal distribution of paediatric acute respiratory tract infections in Ho Chi Minh City, Vietnam. (2018) Ho, Nhan Thi; Thompson, Corinne; Nhan, Le Nguyen Thanh; Van, Hoang Minh Tu; Dung, Nguyen Thanh; Tran My, Phuc; Quang, Vo Minh; Minh, Ngo Ngoc Quang; Tuan, Tran Anh; Hung, Nguyen Thanh; Tuan, Ha Manh; Vinh Chau, Nguyen Van; Wolbers, Marcel; Thwaites, Guy E; Choisy, Marc; Baker, Stephen

Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1. (2018) Currier, Rachel B; Cooper, Anneli; Burrell-Saward, Hollie; MacLeod, Annette; Alsford, Sam

Genome-wide mosaicism in divergence between zoonotic malaria parasite subpopulations with separate sympatric transmission cycles. (2018) Divis, Paul CS; Duffy, Craig W; Kadir, Khamisah A; Singh, Balbir; Conway, David J

Proposal of serovars 17 and 18 of Actinobacillus pleuropneumoniae based on serological and genotypic analysis. (2018) Bossé, JT; LI, Y; Sárközi, R; Fodor, L; Lacouture, S; Gottschalk, M; Amoribieta, MC; Angen, Ø; Nedbalcova, K; Holden, MT; Wren, B

Recognizing the reagent microbiome. (2018) de Goffau, Marcus C; Lager, Susanne; Salter, Susannah J; Wagner, Josef; Kronbichler, Andreas; Charnock-Jones, D Stephen; Peacock, Sharon J; Smith, Gordon CS; Parkhill, Julian

The modern era must end: antibiotic resistance helps us rethink medicine and farming. (2018) de Lima Hutchison, C; Knight, G; Stabler, R; Chandler, C

Monograph

18 new species in the family Herpesviridae. (2018) Gatherer, D; Benko, M; Brandt, C; Bryant, N; Dastjerdi, A; Depledge, D; Doszpoly, A; Gompels, U; Hartley, C; Inoue, N; Jarosinski, K; Kaul, R; Lacoste, V; Norberg, P; Origgi, F; Orton, R; Pellett, P; Schmid, S; Stewart, J; Szpara, M; Trimpert, J; Vaz, P; Waltzek, T; Davison, A

Innovation through Collaboration. (2018) Gompels, U

World Health Organisation Consultation on regulatory expectations for evaluation of nucleic acid vaccines. (2018) Gompels, U

Conference or Workshop Item

Investigating the biogenesis of Campylobacter jejuni outer membrane vesicle production. (2018) Davies, C; Taylor, A; Gundogdu, O; Wren, WB; Elmi, A; Dorrell, N

The Campylobacter jejuni oxidative stress regulator RrpB is associated with a genomic hypervariable region and altered oxidative stress resistance. (2018) Gundogdu, O; Teixeira da Silva, D; Mohammad, B; Elmi, A; Wren, WB; van Vliet, A; Dorrell, N

Investigation of the role of Campylobacter jejuni Type VI secretion system during interactions with host cells. (2018) Liaw, J; Hong, G; Hachani, A; Wren, WB; Gundogdu, O; Dorrell, N

Virus entry complex changes during tissue culture adaptation of human herpesvirus-6A identified by whole genome deep sequencing and structural modelling. (2018) Tweedy, JG; Escriva, E; Topf, M; Gompels, U

Thesis

Using whole genome sequence data to study genomic diversity and develop molecular barcodes to profile Plasmodium malaria parasites. (2018) Díez Benavente, E

Further investigation of the roles of fibronectin-binding proteins CadF and FlpA during Campylobacter jejuni interactions with intestinal epithelial cells. (2018) Hussein, M

Development of anaerobic culturing methods to study the evolution and transmission of the human intestinal microbiota. (2018) Browne, HP

Molecular epidemiological and pathogenesis studies of Streptococcus pneumoniae serotype 1 strains from West Africa. (2018) Ebruke, CN

Long-term population effects of pneumococcal vaccines on carriage of pneumococcal serotypes and subsequent disease in Kenya. (2018) Ojal, JO

Investigation of the Relationship between CGMP Signalling and Calcium Mobilisation in Plasmodium Falciparum with a Focus on the Role of Phosphodiesterases in Sexual Development. (2018) Walker, EM

Other

Emergence of Coxsackie A6 hand-foot-and-mouth disease and comparative severity of Coxsackie B vs. echovirus infections, 2014-2016, UK. (2018) Teo, KW; Lai, FY; Bandi, S; Allen, DJ; Tang, JW

Leishmaniasis. (2018) Burza, S; Croft, SL; Boelaert, M

Author Correction: Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis. (2018) Baddam, R; Kumar, N; Wieler, LH; Lankapalli, AK; Ahmed, N; Peacock, SJ; Semmler, T