Items where Author is "Stewart, Lindsay B"

Year Item Type Full Text

Article

Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites. (2012) Amambua-Ngwa, Alfred; Tetteh, Kevin KA; Manske, Magnus; Gomez-Escobar, Natalia; Stewart, Lindsay B; Deerhake, M Elizabeth; Cheeseman, Ian H; Newbold, Christopher I; Holder, Anthony A; Knuepfer, Ellen; Janha, Omar; Jallow, Muminatou; Campino, Susana; Macinnis, Bronwyn; Kwiatkowski, Dominic P; Conway, David J

Multi-locus genotyping reveals established endemicity of a geographically distinct Plasmodium vivax population in Mauritania, West Africa. (2020) Ba, Hampate; Auburn, Sarah; Jacob, Christopher G; Goncalves, Sonia; Duffy, Craig W; Stewart, Lindsay B; Price, Ric N; Deh, Yacine Boubou; Diallo, Mamadou Yero; Tandia, Abderahmane; Kwiatkowski, Dominic P; Conway, David J

A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. (2017) Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A

Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different populations in areas of malaria endemicity. (2015) Bowyer, Paul W; Stewart, Lindsay B; Aspeling-Jones, Harvey; Mensah-Brown, Henrietta E; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Awandare, Gordon A; Conway, David J

Gene copy number variation throughout the Plasmodium falciparum genome. (2009) Cheeseman, Ian H; Gomez-Escobar, Natalia; Carret, Celine K; Ivens, Alasdair; Stewart, Lindsay B; Tetteh, Kevin KA; Conway, David J

Genomic variation during culture adaptation of genetically complex Plasmodium falciparum clinical isolates. (2023) Claessens, Antoine; Stewart, Lindsay B; Drury, Eleanor; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Diakite, Mahamadou; Kwiatkowski, Dominic P; Awandare, Gordon A; Conway, David J

Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1. (2024) Dans, Madeline G; Boulet, Coralie; Watson, Gabrielle M; Nguyen, William; Dziekan, Jerzy M; Evelyn, Cindy; Reaksudsan, Kitsanapong; Mehra, Somya; Razook, Zahra; Geoghegan, Niall D; Mlodzianoski, Michael J; Goodman, Christopher Dean; Ling, Dawson B; Jonsdottir, Thorey K; Tong, Joshua; Famodimu, Mufuliat Toyin; Kristan, Mojca; Pollard, Harry; Stewart, Lindsay B; Brandner-Garrod, Luke; Sutherland, Colin J; Delves, Michael J; McFadden, Geoffrey I; Barry, Alyssa E; Crabb, Brendan S; de Koning-Ward, Tania F; Rogers, Kelly L; Cowman, Alan F; Tham, Wai-Hong; Sleebs, Brad E; Gilson, Paul R

Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development. (2018) Duffy, Craig W; Amambua-Ngwa, Alfred; Ahouidi, Ambroise D; Diakite, Mahamadou; Awandare, Gordon A; Ba, Hampate; Tarr, Sarah J; Murray, Lee; Stewart, Lindsay B; D'Alessandro, Umberto; Otto, Thomas D; Kwiatkowski, Dominic P; Conway, David J

Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing N-Methyl Amino Acids as Antiplasmodial Agents. (2019) Fagundez, Catherine; Sellanes, Diver; Peña, Stella; Scarone, Laura; Aguiar, Anna CC; de Souza, Juliana O; Guido, Rafael VC; Stewart, Lindsay; Yardley, Vanessa; Ottilie, Sabine; Winzeler, Elizabeth A; Gamo, Francisco-J; Sanz, Laura M; Serra, Gloria L

Artemisone--a highly active antimalarial drug of the artemisinin class. (2006) Haynes, Richard K; Fugmann, Burkhard; Stetter, Jörg; Rieckmann, Karl; Heilmann, Hans-Dietrich; Chan, Ho-Wai; Cheung, Man-Ki; Lam, Wai-Lun; Wong, Ho-Ning; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Peters, Wallace; Robinson, Brian L; Edstein, Michael D; Kotecka, Barbara; Kyle, Dennis E; Beckermann, Bernhard; Gerisch, Michael; Radtke, Martin; Schmuck, Gabriele; Steinke, Wolfram; Wollborn, Ute; Schmeer, Karl; Römer, Axel

Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. (2007) Haynes, Richard K; Wong, Ho-Ning; Lee, Kin-Wo; Lung, Chung-Man; Shek, Lai Yung; Williams, Ian D; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Wong, Vincent KW; Ko, Ben CB

Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes. (2022) Hocking, Suzanne E; Stewart, Lindsay B; Freville, Aline; Reid, Adam J; Tarr, Sarah J; Tetteh, Kevin KA; Flueck, Christian; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Diakite, Mahamadou; Awandare, Gordon A; Conway, David J

Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines. (2018) Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty. (2019) Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria. (2018) Lee, Hyun Jae; Georgiadou, Athina; Walther, Michael; Nwakanma, Davis; Stewart, Lindsay B; Levin, Michael; Otto, Thomas D; Conway, David J; Coin, Lachlan J; Cunnington, Aubrey J

Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana. (2015) Mensah-Brown, Henrietta E; Amoako, Nicholas; Abugri, James; Stewart, Lindsay B; Agongo, Godfred; Dickson, Emmanuel K; Ofori, Michael F; Stoute, José A; Conway, David J; Awandare, Gordon A

Multiplication rate variation in the human malaria parasite Plasmodium falciparum. (2017) Murray, Lee; Stewart, Lindsay B; Tarr, Sarah J; Ahouidi, Ambroise D; Diakite, Mahamadou; Amambua-Ngwa, Alfred; Conway, David J

Phylogenetic analysis and description of Eperythrozoon coccoides, proposal to transfer to the genus Mycoplasma as Mycoplasma coccoides comb. nov. and Request for an Opinion. (2005) Neimark, Harold; Peters, Wallace; Robinson, Brian L; Stewart, Lindsay B

Failure of rapid diagnostic tests in Plasmodium falciparum malaria cases among travelers to the UK and Ireland: Identification and characterisation of the parasites. (2021) Nolder, Debbie; Stewart, Lindsay; Tucker, Julie; Ibrahim, Amy; Gray, Adam; Corrah, Tumena; Gallagher, Carmel; John, Laurence; O'Brien, Edel; Aggarwal, Dinesh; Benavente, Ernest Diez; van Schalkwyk, Donelly; Henriques, Gisela; Sepúlveda, Nuno; Campino, Susana; Chiodini, Peter; Sutherland, Colin; Beshir, Khalid B

Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level. (2020) Nyarko, Prince B; Tarr, Sarah J; Aniweh, Yaw; Stewart, Lindsay B; Conway, David J; Awandare, Gordon A

Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum. (2010) Ochola, Lynette Isabella; Tetteh, Kevin KA; Stewart, Lindsay B; Riitho, Victor; Marsh, Kevin; Conway, David J

Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres. (2018) Otto, Thomas D; Böhme, Ulrike; Sanders, Mandy; Reid, Adam; Bruske, Ellen I; Duffy, Craig W; Bull, Pete C; Pearson, Richard D; Abdi, Abdirahman; Dimonte, Sandra; Stewart, Lindsay B; Campino, Susana; Kekre, Mihir; Hamilton, William L; Claessens, Antoine; Volkman, Sarah K; Ndiaye, Daouda; Amambua-Ngwa, Alfred; Diakite, Mahamadou; Fairhurst, Rick M; Conway, David J; Franck, Matthias; Newbold, Chris I; Berriman, Matt

The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials. (2002) Peters, W; Fleck, SL; Robinson, BL; Stewart, LB; Jefford, CW

The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines. (2003) Peters, W; Stewart, LB; Robinson, BL

The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. (2005) Peters, W; Stewart, LB; Robinson, BL

Synthesis of cyclohexapeptides as antimalarial and anti-trypanosomal agents. (2014) Peña, S; Fagundez, C; Medeiros, A; Comini, M; Scarone, L; Sellanes, D; Manta, E; Tulla-Puche, J; Albericio, F; Stewart, L; Yardley, V; Serra, G

Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. (2012) Peña, Stella; Scarone, Laura; Manta, Eduardo; Stewart, Lindsay; Yardley, Vanessa; Croft, Simon; Serra, Gloria

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. (2014) Preston, Mark D; Campino, Susana; Assefa, Samuel A; Echeverry, Diego F; Ocholla, Harold; Amambua-Ngwa, Alfred; Stewart, Lindsay B; Conway, David J; Borrmann, Steffen; Michon, Pascal; Zongo, Issaka; Ouédraogo, Jean-Bosco; Djimde, Abdoulaye A; Doumbo, Ogobara K; Nosten, Francois; Pain, Arnab; Bousema, Teun; Drakeley, Chris J; Fairhurst, Rick M; Sutherland, Colin J; Roper, Cally; Clark, Taane G

The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate. (2004) Stewart, LB; Peters, W; Robinson, BL

Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites. (2020) Stewart, Lindsay B; Diaz-Ingelmo, Ofelia; Claessens, Antoine; Abugri, James; Pearson, Richard D; Goncalves, Sonia; Drury, Eleanor; Kwiatkowski, Dominic P; Awandare, Gordon A; Conway, David J

Multiplication rate variation of malaria parasites from hospital cases and community infections. (2025) Stewart, Lindsay B; Escolar, Elena Lantero; Philpott, James; Claessens, Antoine; Amambua-Ngwa, Alfred; Conway, David J

Intrinsic multiplication rate variation of Plasmodium falciparum in clinical isolates prior to elimination in Malaysia. (2025) Stewart, Lindsay B; Escolar, Elena Lantero; Philpott, James; Cox-Singh, Janet; Singh, Balbir; Conway, David J picture_as_pdf

Plasmodium falciparum Sexual Commitment Rate Variation among Clinical Isolates and Diverse Laboratory-Adapted Lines. (2022) Stewart, Lindsay B; Freville, Aline; Voss, Till S; Baker, David A; Awandare, Gordon A; Conway, David J

Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum. (2018) Tarr, Sarah J; Díaz-Ingelmo, Ofelia; Stewart, Lindsay B; Hocking, Suzanne E; Murray, Lee; Duffy, Craig W; Otto, Thomas D; Chappell, Lia; Rayner, Julian C; Awandare, Gordon A; Conway, David J

Prospective identification of malaria parasite genes under balancing selection. (2009) Tetteh, Kevin KA; Stewart, Lindsay B; Ochola, Lynette Isabella; Amambua-Ngwa, Alfred; Thomas, Alan W; Marsh, Kevin; Weedall, Gareth D; Conway, David J

Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. (2014) Tewari, Rita; Patzewitz, Eva-Maria; Poulin, Benoit; Stewart, Lindsay; Baker, David A

Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG). (2018) Tsagris, Denise J; Birchall, Kristian; Bouloc, Nathalie; Large, Jonathan M; Merritt, Andy; Smiljanic-Hurley, Ela; Wheldon, Mary; Ansell, Keith H; Kettleborough, Catherine; Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A

Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. (2007) Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL

Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. (2007) Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Bongard, Emily; Robinson, Brian L; Peters, Wallace; Croft, Simon L

Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity. (2009) Williams, Geoffrey S; Mweya, Clement; Stewart, Laveta; Mtove, George; Reyburn, Hugh; Cook, Jackie; Corran, Patrick H; Riley, Eleanor M; Drakeley, Chris J

Treatment Failure in a UK Malaria Patient Harboring Genetically Variant Plasmodium falciparum From Uganda With Reduced In Vitro Susceptibility to Artemisinin and Lumefantrine. (2023) van Schalkwyk, Donelly A; Pratt, Sade; Nolder, Debbie; Stewart, Lindsay B; Liddy, Helen; Muwanguzi-Karugaba, Julian; Beshir, Khalid B; Britten, Dawn; Victory, Emma; Rogers, Claire; Millard, James; Brown, Michael; Nabarro, Laura E; Taylor, Andrew; Young, Bernadette C; Chiodini, Peter L; Sutherland, Colin J

Conference or Workshop Item

Studies of natural selection on malaria parasite merozoites in relation to invasion and immunity. (2008) Tetteh, K; Ochola, L; Stewart, L; Ngwa, A; Marsh, K; Conway, D