Hocking, Suzanne E; Stewart, Lindsay B; Freville, Aline; Reid, Adam J; Tarr, Sarah J; Tetteh, Kevin KA; Flueck, Christian; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Diakite, Mahamadou; +2 more... Awandare, Gordon A; Conway, David J; (2022) Highly Variable Expression of Merozoite Surface Protein MSPDBL2 in Diverse Plasmodium falciparum Clinical Isolates and Transcriptome Scans for Correlating Genes. mBio, 13 (4). e0194822-. ISSN 2161-2129 DOI: https://doi.org/10.1128/mbio.01948-22

Stewart, Lindsay B; Freville, Aline; Voss, Till S; Baker, David A; Awandare, Gordon A; Conway, David J; (2022) Plasmodium falciparum Sexual Commitment Rate Variation among Clinical Isolates and Diverse Laboratory-Adapted Lines. Microbiology spectrum, 10 (6). e0223422-. ISSN 2165-0497 DOI: https://doi.org/10.1128/spectrum.02234-22

Nolder, Debbie; Stewart, Lindsay; Tucker, Julie; Ibrahim, Amy; Gray, Adam; Corrah, Tumena; Gallagher, Carmel; John, Laurence; O'Brien, Edel; Aggarwal, Dinesh; +8 more... Benavente, Ernest Diez; van Schalkwyk, Donelly; Henriques, Gisela; Sepúlveda, Nuno; Campino, Susana; Chiodini, Peter; Sutherland, Colin; Beshir, Khalid B; (2021) Failure of rapid diagnostic tests in Plasmodium falciparum malaria cases among travelers to the UK and Ireland: Identification and characterisation of the parasites. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 108. pp. 137-144. ISSN 1201-9712 DOI: https://doi.org/10.1016/j.ijid.2021.05.008

Ba, Hampate; Auburn, Sarah; Jacob, Christopher G; Goncalves, Sonia; Duffy, Craig W; Stewart, Lindsay B; Price, Ric N; Deh, Yacine Boubou; Diallo, Mamadou Yero; Tandia, Abderahmane; +2 more... Kwiatkowski, Dominic P; Conway, David J; (2020) Multi-locus genotyping reveals established endemicity of a geographically distinct Plasmodium vivax population in Mauritania, West Africa. PLOS NEGLECTED TROPICAL DISEASES, 14 (12). e0008945-. ISSN 1935-2727 DOI: https://doi.org/10.1371/journal.pntd.0008945

Nyarko, Prince B; Tarr, Sarah J; Aniweh, Yaw; Stewart, Lindsay B; Conway, David J; Awandare, Gordon A; (2020) Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level. Scientific reports, 10 (1). 245-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-019-56386-y

Stewart, Lindsay B; Diaz-Ingelmo, Ofelia; Claessens, Antoine; Abugri, James; Pearson, Richard D; Goncalves, Sonia; Drury, Eleanor; Kwiatkowski, Dominic P; Awandare, Gordon A; Conway, David J; (2020) Intrinsic multiplication rate variation and plasticity of human blood stage malaria parasites. COMMUNICATIONS BIOLOGY, 3 (1). 624-. ISSN 2399-3642 DOI: https://doi.org/10.1038/s42003-020-01349-7

Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; +5 more... Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2019) Potent bicyclic inhibitors of malarial cGMP-dependent protein kinase: approaches to combining improvements in cell potency, selectivity and structural novelty. Bioorganic & medicinal chemistry letters, 29 (19). 126610-. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2019.08.014

Duffy, Craig W; Amambua-Ngwa, Alfred; Ahouidi, Ambroise D; Diakite, Mahamadou; Awandare, Gordon A; Ba, Hampate; Tarr, Sarah J; Murray, Lee; Stewart, Lindsay B; D'Alessandro, Umberto; +3 more... Otto, Thomas D; Kwiatkowski, Dominic P; Conway, David J; (2018) Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development. Scientific reports, 8 (1). 15763-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-018-34078-3

Large, Jonathan M; Birchall, Kristian; Bouloc, Nathalie S; Merritt, Andy T; Smiljanic-Hurley, Ela; Tsagris, Denise J; Wheldon, Mary C; Ansell, Keith H; Coombs, Peter J; Kettleborough, Catherine A; +5 more... Whalley, David; Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2018) Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines. Bioorganic & medicinal chemistry letters, 29 (3). pp. 509-514. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.11.039

Lee, Hyun Jae; Georgiadou, Athina; Walther, Michael; Nwakanma, Davis; Stewart, Lindsay B; Levin, Michael; Otto, Thomas D; Conway, David J; Coin, Lachlan J; Cunnington, Aubrey J; (2018) Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria. Science translational medicine, 10 (447). eaar3619-eaar3619. ISSN 1946-6234 DOI: https://doi.org/10.1126/scitranslmed.aar3619

Otto, Thomas D; Böhme, Ulrike; Sanders, Mandy; Reid, Adam; Bruske, Ellen I; Duffy, Craig W; Bull, Pete C; Pearson, Richard D; Abdi, Abdirahman; Dimonte, Sandra; +14 more... Stewart, Lindsay B; Campino, Susana; Kekre, Mihir; Hamilton, William L; Claessens, Antoine; Volkman, Sarah K; Ndiaye, Daouda; Amambua-Ngwa, Alfred; Diakite, Mahamadou; Fairhurst, Rick M; Conway, David J; Franck, Matthias; Newbold, Chris I; Berriman, Matt; (2018) Long read assemblies of geographically dispersed Plasmodium falciparum isolates reveal highly structured subtelomeres. Wellcome open research, 3. 52-. ISSN 2398-502X DOI: https://doi.org/10.12688/wellcomeopenres.14571.1

Tarr, Sarah J; Díaz-Ingelmo, Ofelia; Stewart, Lindsay B; Hocking, Suzanne E; Murray, Lee; Duffy, Craig W; Otto, Thomas D; Chappell, Lia; Rayner, Julian C; Awandare, Gordon A; +1 more... Conway, David J; (2018) Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum. BMC GENOMICS, 19 (1). 894-. ISSN 1471-2164 DOI: https://doi.org/10.1186/s12864-018-5257-x

Tsagris, Denise J; Birchall, Kristian; Bouloc, Nathalie; Large, Jonathan M; Merritt, Andy; Smiljanic-Hurley, Ela; Wheldon, Mary; Ansell, Keith H; Kettleborough, Catherine; Whalley, David; +4 more... Stewart, Lindsay B; Bowyer, Paul W; Baker, David A; Osborne, Simon A; (2018) Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG). Bioorganic & medicinal chemistry letters, 28 (19). pp. 3168-3173. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2018.08.028

Baker, David A; Stewart, Lindsay B; Large, Jonathan M; Bowyer, Paul W; Ansell, Keith H; Jiménez-Díaz, María B; El Bakkouri, Majida; Birchall, Kristian; Dechering, Koen J; Bouloc, Nathalie S; +19 more... Coombs, Peter J; Whalley, David; Harding, Denise J; Smiljanic-Hurley, Ela; Wheldon, Mary C; Walker, Eloise M; Dessens, Johannes T; Lafuente, María José; Sanz, Laura M; Gamo, Francisco-Javier; Ferrer, Santiago B; Hui, Raymond; Bousema, Teun; Angulo-Barturén, Iñigo; Merritt, Andy T; Croft, Simon L; Gutteridge, Winston E; Kettleborough, Catherine A; Osborne, Simon A; (2017) A potent series targeting the malarial cGMP-dependent protein kinase clears infection and blocks transmission. Nature communications, 8 (1). 430-. ISSN 2041-1723 DOI: https://doi.org/10.1038/s41467-017-00572-x

Murray, Lee; Stewart, Lindsay B; Tarr, Sarah J; Ahouidi, Ambroise D; Diakite, Mahamadou; Amambua-Ngwa, Alfred; Conway, David J; (2017) Multiplication rate variation in the human malaria parasite Plasmodium falciparum. Scientific reports, 7 (1). 6436-. ISSN 2045-2322 DOI: https://doi.org/10.1038/s41598-017-06295-9

Bowyer, Paul W; Stewart, Lindsay B; Aspeling-Jones, Harvey; Mensah-Brown, Henrietta E; Ahouidi, Ambroise D; Amambua-Ngwa, Alfred; Awandare, Gordon A; Conway, David J; (2015) Variation in Plasmodium falciparum erythrocyte invasion phenotypes and merozoite ligand gene expression across different populations in areas of malaria endemicity. Infection and immunity, 83 (6). pp. 2575-2582. ISSN 0019-9567 DOI: https://doi.org/10.1128/IAI.03009-14 Full text not available from this repository.

Mensah-Brown, Henrietta E; Amoako, Nicholas; Abugri, James; Stewart, Lindsay B; Agongo, Godfred; Dickson, Emmanuel K; Ofori, Michael F; Stoute, José A; Conway, David J; Awandare, Gordon A; (2015) Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana. The Journal of infectious diseases, 212 (8). pp. 1288-1297. ISSN 0022-1899 DOI: https://doi.org/10.1093/infdis/jiv207 Full text not available from this repository.

Peña, S; Fagundez, C; Medeiros, A; Comini, M; Scarone, L; Sellanes, D; Manta, E; Tulla-Puche, J; Albericio, F; Stewart, L; +2 more... Yardley, V; Serra, G; (2014) Synthesis of cyclohexapeptides as antimalarial and anti-trypanosomal agents. MedChemComm, 5 (9). pp. 1309-1316. ISSN 2040-2503 DOI: https://doi.org/10.1039/c4md00135d Full text not available from this repository.

Preston, Mark D; Campino, Susana; Assefa, Samuel A; Echeverry, Diego F; Ocholla, Harold; Amambua-Ngwa, Alfred; Stewart, Lindsay B; Conway, David J; Borrmann, Steffen; Michon, Pascal; +12 more... Zongo, Issaka; Ouédraogo, Jean-Bosco; Djimde, Abdoulaye A; Doumbo, Ogobara K; Nosten, Francois; Pain, Arnab; Bousema, Teun; Drakeley, Chris J; Fairhurst, Rick M; Sutherland, Colin J; Roper, Cally; Clark, Taane G; (2014) A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains. Nature communications, 5 (1). 4052-. ISSN 2041-1723 DOI: https://doi.org/10.1038/ncomms5052

Tewari, Rita; Patzewitz, Eva-Maria; Poulin, Benoit; Stewart, Lindsay; Baker, David A; (2014) Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. PloS one, 9 (5). e96923-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0096923

Amambua-Ngwa, Alfred; Tetteh, Kevin KA; Manske, Magnus; Gomez-Escobar, Natalia; Stewart, Lindsay B; Deerhake, M Elizabeth; Cheeseman, Ian H; Newbold, Christopher I; Holder, Anthony A; Knuepfer, Ellen; +6 more... Janha, Omar; Jallow, Muminatou; Campino, Susana; Macinnis, Bronwyn; Kwiatkowski, Dominic P; Conway, David J; (2012) Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites. PLoS genetics, 8 (11). e1002992-. ISSN 1553-7390 DOI: https://doi.org/10.1371/journal.pgen.1002992

Peña, Stella; Scarone, Laura; Manta, Eduardo; Stewart, Lindsay; Yardley, Vanessa; Croft, Simon; Serra, Gloria; (2012) Synthesis of a Microcystis aeruginosa predicted metabolite with antimalarial activity. Bioorganic & medicinal chemistry letters, 22 (15). pp. 4994-4997. ISSN 0960-894X DOI: https://doi.org/10.1016/j.bmcl.2012.06.028 Full text not available from this repository.

Ochola, Lynette Isabella; Tetteh, Kevin KA; Stewart, Lindsay B; Riitho, Victor; Marsh, Kevin; Conway, David J; (2010) Allele frequency-based and polymorphism-versus-divergence indices of balancing selection in a new filtered set of polymorphic genes in Plasmodium falciparum. Molecular biology and evolution, 27 (10). pp. 2344-2351. ISSN 0737-4038 DOI: https://doi.org/10.1093/molbev/msq119

Cheeseman, Ian H; Gomez-Escobar, Natalia; Carret, Celine K; Ivens, Alasdair; Stewart, Lindsay B; Tetteh, Kevin KA; Conway, David J; (2009) Gene copy number variation throughout the Plasmodium falciparum genome. BMC genomics, 10 (1). 353-. ISSN 1471-2164 DOI: https://doi.org/10.1186/1471-2164-10-353

Tetteh, Kevin KA; Stewart, Lindsay B; Ochola, Lynette Isabella; Amambua-Ngwa, Alfred; Thomas, Alan W; Marsh, Kevin; Weedall, Gareth D; Conway, David J; (2009) Prospective identification of malaria parasite genes under balancing selection. PloS one, 4 (5). e5568-. ISSN 1932-6203 DOI: https://doi.org/10.1371/journal.pone.0005568

Williams, Geoffrey S; Mweya, Clement; Stewart, Laveta; Mtove, George; Reyburn, Hugh; Cook, Jackie; Corran, Patrick H; Riley, Eleanor M; Drakeley, Chris J; (2009) Immunophoretic rapid diagnostic tests as a source of immunoglobulins for estimating malaria sero-prevalence and transmission intensity. Malaria journal, 8 (1). 168-. ISSN 1475-2875 DOI: https://doi.org/10.1186/1475-2875-8-168

Tetteh, K; Ochola, L; Stewart, L; Ngwa, A; Marsh, K; Conway, D; (2008) Studies of natural selection on malaria parasite merozoites in relation to invasion and immunity. [Conference or Workshop Item] https://researchonline.lshtm.ac.uk/id/eprint/7909 Full text not available from this repository.

Haynes, Richard K; Wong, Ho-Ning; Lee, Kin-Wo; Lung, Chung-Man; Shek, Lai Yung; Williams, Ian D; Croft, Simon L; Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; +2 more... Wong, Vincent KW; Ko, Ben CB; (2007) Preparation of N-sulfonyl- and N-carbonyl-11-azaartemisinins with greatly enhanced thermal stabilities: in vitro antimalarial activities. ChemMedChem, 2 (10). pp. 1464-1479. ISSN 1860-7179 DOI: https://doi.org/10.1002/cmdc.200700065 Full text not available from this repository.

Vivas, L; Rattray, L; Stewart, LB; Robinson, BL; Fugmann, B; Haynes, RK; Peters, W; Croft, SL; (2007) Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. The Journal of antimicrobial chemotherapy, 59 (4). pp. 658-665. ISSN 0305-7453 DOI: https://doi.org/10.1093/jac/dkl563 Full text not available from this repository.

Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Bongard, Emily; Robinson, Brian L; Peters, Wallace; Croft, Simon L; (2007) Anti-malarial efficacy of pyronaridine and artesunate in combination in vitro and in vivo. Acta tropica, 105 (3). pp. 222-228. ISSN 0001-706X DOI: https://doi.org/10.1016/j.actatropica.2007.12.005 Full text not available from this repository.

Haynes, Richard K; Fugmann, Burkhard; Stetter, Jörg; Rieckmann, Karl; Heilmann, Hans-Dietrich; Chan, Ho-Wai; Cheung, Man-Ki; Lam, Wai-Lun; Wong, Ho-Ning; Croft, Simon L; +16 more... Vivas, Livia; Rattray, Lauren; Stewart, Lindsay; Peters, Wallace; Robinson, Brian L; Edstein, Michael D; Kotecka, Barbara; Kyle, Dennis E; Beckermann, Bernhard; Gerisch, Michael; Radtke, Martin; Schmuck, Gabriele; Steinke, Wolfram; Wollborn, Ute; Schmeer, Karl; Römer, Axel; (2006) Artemisone--a highly active antimalarial drug of the artemisinin class. Angewandte Chemie (International ed in English), 45 (13). pp. 2082-2088. ISSN 1433-7851 DOI: https://doi.org/10.1002/anie.200503071 Full text not available from this repository.

Neimark, Harold; Peters, Wallace; Robinson, Brian L; Stewart, Lindsay B; (2005) Phylogenetic analysis and description of Eperythrozoon coccoides, proposal to transfer to the genus Mycoplasma as Mycoplasma coccoides comb. nov. and Request for an Opinion. International journal of systematic and evolutionary microbiology, 55 (Pt 3). pp. 1385-1391. ISSN 1466-5026 DOI: https://doi.org/10.1099/ijs.0.63437-0 Full text not available from this repository.

Peters, W; Stewart, LB; Robinson, BL; (2005) The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. Annals of tropical medicine and parasitology, 99 (5). pp. 457-472. ISSN 0003-4983 DOI: https://doi.org/10.1179/136485905X51274 Full text not available from this repository.

Stewart, LB; Peters, W; Robinson, BL; (2004) The chemotherapy of rodent malaria. LXII. Drug combinations to impede the selection of drug resistance, part 5: rates of development of resistance to some inhibitors of folate metabolism and to artesunate. Annals of tropical medicine and parasitology, 98 (8). pp. 763-783. ISSN 0003-4983 DOI: https://doi.org/10.1179/136485913X13789813917625 Full text not available from this repository.

Peters, W; Stewart, LB; Robinson, BL; (2003) The chemotherapy of rodent malaria. LXI. Drug combinations to impede the selection of drug resistance, part 4: the potential role of 8-aminoquinolines. Annals of tropical medicine and parasitology, 97 (3). pp. 221-236. ISSN 0003-4983 DOI: https://doi.org/10.1179/000349803235001886 Full text not available from this repository.

Peters, W; Fleck, SL; Robinson, BL; Stewart, LB; Jefford, CW; (2002) The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials. Annals of tropical medicine and parasitology, 96 (6). pp. 559-573. ISSN 0003-4983 DOI: https://doi.org/10.1179/000349802125001744 Full text not available from this repository.