Items where Author is "Delves, MJ"
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Number of items: 40.
Article
Angrisano, F;
Delves, MJ;
Sturm, A;
Mollard, V;
McFadden, GI;
Sinden, RE;
Baum, J;
(2011)
A GFP-actin reporter line to explore microfilament dynamics across the malaria parasite lifecycle.
Molecular and biochemical parasitology, 182 (1-2).
pp. 93-6.
ISSN 0166-6851
DOI: https://doi.org/10.1016/j.molbiopara.2011.11.008
Full text not available from this repository.
Angrisano, F;
Riglar, DT;
Sturm, A;
Volz, JC;
Delves, MJ;
Zuccala, ES;
Turnbull, L;
Dekiwadia, C;
Olshina, MA;
Marapana, DS;
+11 more...
Wong, W;
Mollard, V;
Bradin, CH;
Tonkin, CJ;
Gunning, PW;
Ralph, SA;
Whitchurch, CB;
Sinden, RE;
Cowman, AF;
McFadden, GI;
Baum, J;
(2012)
Spatial localisation of actin filaments across developmental stages of the malaria parasite.
PloS one, 7 (2).
e32188.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0032188
Baragaña, B;
Norcross, NR;
Wilson, C;
Porzelle, A;
Hallyburton, I;
Grimaldi, R;
Osuna-Cabello, M;
Norval, S;
Riley, J;
Stojanovski, L;
+17 more...
Simeons, FR;
Wyatt, PG;
Delves, MJ;
Meister, S;
Duffy, S;
Avery, VM;
Winzeler, EA;
Sinden, RE;
Wittlin, S;
Frearson, JA;
Gray, DW;
Fairlamb, AH;
Waterson, D;
Campbell, SF;
Willis, P;
Read, KD;
Gilbert, IH;
(2016)
Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.
Journal of medicinal chemistry, 59 (21).
pp. 9672-9685.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.6b00723
Full text not available from this repository.
Biagini, GA;
Fisher, N;
Shone, AE;
Mubaraki, MA;
Srivastava, A;
Hill, A;
Antoine, T;
Warman, AJ;
Davies, J;
Pidathala, C;
+22 more...
Amewu, RK;
Leung, SC;
Sharma, R;
Gibbons, P;
Hong, DW;
Pacorel, B;
Lawrenson, AS;
Charoensutthivarakul, S;
Taylor, L;
Berger, O;
Mbekeani, A;
Stocks, PA;
Nixon, GL;
Chadwick, J;
Hemingway, J;
Delves, MJ;
Sinden, RE;
Zeeman, AM;
Kocken, CH;
Berry, NG;
O'Neill, PM;
Ward, SA;
(2012)
Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.
Proceedings of the National Academy of Sciences of the United States of America, 109 (21).
pp. 8298-303.
ISSN 0027-8424
DOI: https://doi.org/10.1073/pnas.1205651109
Full text not available from this repository.
Blagborough, AM;
Delves, MJ;
Ramakrishnan, C;
Lal, K;
Butcher, G;
Sinden, RE;
(2013)
Assessing transmission blockade in Plasmodium spp.
Methods in molecular biology (Clifton, NJ), 923.
pp. 577-600.
ISSN 1064-3745
DOI: https://doi.org/10.1007/978-1-62703-026-7_40
Full text not available from this repository.
Churcher, TS;
Blagborough, AM;
Delves, M;
Ramakrishnan, C;
Kapulu, MC;
Williams, AR;
Biswas, S;
Da, DF;
Cohuet, A;
Sinden, RE;
(2012)
Measuring the blockade of malaria transmission-an analysis of the Standard Membrane Feeding Assay.
International journal for parasitology, 42 (11).
pp. 1037-44.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.09.002
Full text not available from this repository.
Delves, M;
Plouffe, D;
Scheurer, C;
Meister, S;
Wittlin, S;
Winzeler, EA;
Sinden, RE;
Leroy, D;
(2012)
The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.
PLoS medicine, 9 (2).
e1001169.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1001169
Delves, MJ;
(2012)
Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs.
Future medicinal chemistry, 4 (18).
pp. 2251-63.
ISSN 1756-8919
DOI: https://doi.org/10.4155/fmc.12.182
Full text not available from this repository.
Delves, MJ;
Angrisano, F;
Blagborough, AM;
(2018)
Antimalarial Transmission-Blocking Interventions: Past, Present, and Future.
Trends in parasitology.
ISSN 1471-4922
DOI: https://doi.org/10.1016/j.pt.2018.07.001
Full text not available from this repository.
Delves, MJ;
Ramakrishnan, C;
Blagborough, AM;
Leroy, D;
Wells, TN;
Sinden, RE;
(2012)
A high-throughput assay for the identification of malarial transmission-blocking drugs and vaccines.
International journal for parasitology, 42 (11).
pp. 999-1006.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2012.08.009
Full text not available from this repository.
Delves, MJ;
Ruecker, A;
Straschil, U;
Lelièvre, J;
Marques, S;
López-Barragán, MJ;
Herreros, E;
Sinden, RE;
(2013)
Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.
Antimicrobial agents and chemotherapy, 57 (7).
pp. 3268-74.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.00325-13
Full text not available from this repository.
Delves, MJ;
Sinden, RE;
(2010)
A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies.
Malaria journal, 9.
p. 35.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-9-35
Delves, MJ;
Straschil, U;
Ruecker, A;
Miguel-Blanco, C;
Marques, S;
Dufour, AC;
Baum, J;
Sinden, RE;
(2016)
Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions.
Nature protocols, 11 (9).
pp. 1668-80.
ISSN 1754-2189
DOI: https://doi.org/10.1038/nprot.2016.096
Full text not available from this repository.
Kan, A;
Tan, YH;
Angrisano, F;
Hanssen, E;
Rogers, KL;
Whitehead, L;
Mollard, VP;
Cozijnsen, A;
Delves, MJ;
Crawford, S;
+5 more...
Sinden, RE;
McFadden, GI;
Leckie, C;
Bailey, J;
Baum, J;
(2014)
Quantitative analysis of Plasmodium ookinete motion in three dimensions suggests a critical role for cell shape in the biomechanics of malaria parasite gliding motility.
Cellular microbiology, 16 (5).
pp. 734-50.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12283
Full text not available from this repository.
Lal, K;
Delves, MJ;
Bromley, E;
Wastling, JM;
Tomley, FM;
Sinden, RE;
(2008)
Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development.
International journal for parasitology, 39 (7).
pp. 755-61.
ISSN 0020-7519
DOI: https://doi.org/10.1016/j.ijpara.2008.11.008
Full text not available from this repository.
Lamour, SD;
Straschil, U;
Saric, J;
Delves, MJ;
(2014)
Changes in metabolic phenotypes of Plasmodium falciparum in vitro cultures during gametocyte development.
Malaria journal, 13.
p. 468.
ISSN 1475-2875
DOI: https://doi.org/10.1186/1475-2875-13-468
Le Bihan, A;
de Kanter, R;
Angulo-Barturen, I;
Binkert, C;
Boss, C;
Brun, R;
Brunner, R;
Buchmann, S;
Burrows, J;
Dechering, KJ;
+30 more...
Delves, M;
Ewerling, S;
Ferrer, S;
Fischli, C;
Gamo-Benito, FJ;
Gnädig, NF;
Heidmann, B;
Jiménez-Díaz, MB;
Leroy, D;
Martínez, MS;
Meyer, S;
Moehrle, JJ;
Ng, CL;
Noviyanti, R;
Ruecker, A;
Sanz, LM;
Sauerwein, RW;
Scheurer, C;
Schleiferboeck, S;
Sinden, R;
Snyder, C;
Straimer, J;
Wirjanata, G;
Marfurt, J;
Price, RN;
Weller, T;
Fischli, W;
Fidock, DA;
Clozel, M;
Wittlin, S;
(2016)
Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
PLoS medicine, 13 (10).
e1002138.
ISSN 1549-1277
DOI: https://doi.org/10.1371/journal.pmed.1002138
Leba, LJ;
Musset, L;
Pelleau, S;
Estevez, Y;
Birer, C;
Briolant, S;
Witkowski, B;
Ménard, D;
Delves, MJ;
Legrand, E;
+2 more...
Duplais, C;
Popovici, J;
(2015)
Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay.
Malaria journal, 14.
p. 234.
ISSN 1475-2875
DOI: https://doi.org/10.1186/s12936-015-0752-x
Leven, M;
Knaab, TC;
Held, J;
Duffy, S;
Meister, S;
Fischli, C;
Meitzner, D;
Lehmann, U;
Lungerich, B;
Kuna, K;
+8 more...
Stahlke, P;
Delves, MJ;
Buchholz, M;
Winzeler, EA;
Avery, VM;
Mordmüller, B;
Wittlin, S;
Kurz, T;
(2017)
3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.
Journal of medicinal chemistry, 60 (14).
pp. 6036-6044.
ISSN 0022-2623
DOI: https://doi.org/10.1021/acs.jmedchem.7b00140
Full text not available from this repository.
Malmquist, NA;
Sundriyal, S;
Caron, J;
Chen, P;
Witkowski, B;
Menard, D;
Suwanarusk, R;
Renia, L;
Nosten, F;
Jiménez-Díaz, MB;
+13 more...
Angulo-Barturen, I;
Santos Martínez, M;
Ferrer, S;
Sanz, LM;
Gamo, FJ;
Wittlin, S;
Duffy, S;
Avery, VM;
Ruecker, A;
Delves, MJ;
Sinden, RE;
Fuchter, MJ;
Scherf, A;
(2014)
Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
Antimicrobial agents and chemotherapy, 59 (2).
pp. 950-9.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.04419-14
Full text not available from this repository.
Marques, J;
Valle-Delgado, JJ;
Urbán, P;
Baró, E;
Prohens, R;
Mayor, A;
Cisteró, P;
Delves, M;
Sinden, RE;
Grandfils, C;
+3 more...
de Paz, JL;
García-Salcedo, JA;
Fernàndez-Busquets, X;
(2016)
Adaptation of targeted nanocarriers to changing requirements in antimalarial drug delivery.
Nanomedicine, 13 (2).
pp. 515-525.
ISSN 1549-9634
DOI: https://doi.org/10.1016/j.nano.2016.09.010
Marques, SR;
Ramakrishnan, C;
Carzaniga, R;
Blagborough, AM;
Delves, MJ;
Talman, AM;
Sinden, RE;
(2014)
An essential role of the basal body protein SAS-6 in Plasmodium male gamete development and malaria transmission.
Cellular microbiology, 17 (2).
pp. 191-206.
ISSN 1462-5814
DOI: https://doi.org/10.1111/cmi.12355
Miguel-Blanco, C;
Lelièvre, J;
Delves, MJ;
Bardera, AI;
Presa, JL;
López-Barragán, MJ;
Ruecker, A;
Marques, S;
Sinden, RE;
Herreros, E;
(2015)
Imaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.
Antimicrobial agents and chemotherapy, 59 (6).
pp. 3298-305.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.04684-14
Full text not available from this repository.
Miguel-Blanco, C;
Molina, I;
Bardera, AI;
Díaz, B;
de Las Heras, L;
Lozano, S;
González, C;
Rodrigues, J;
Delves, MJ;
Ruecker, A;
+7 more...
Colmenarejo, G;
Viera, S;
Martínez-Martínez, MS;
Fernández, E;
Baum, J;
Sinden, RE;
Herreros, E;
(2017)
Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Nature communications, 8.
p. 15160.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms15160
Nilsen, A;
LaCrue, AN;
White, KL;
Forquer, IP;
Cross, RM;
Marfurt, J;
Mather, MW;
Delves, MJ;
Shackleford, DM;
Saenz, FE;
+31 more...
Morrisey, JM;
Steuten, J;
Mutka, T;
Li, Y;
Wirjanata, G;
Ryan, E;
Duffy, S;
Kelly, JX;
Sebayang, BF;
Zeeman, AM;
Noviyanti, R;
Sinden, RE;
Kocken, CHM;
Price, RN;
Avery, VM;
Angulo-Barturen, I;
Jiménez-Díaz, MB;
Ferrer, S;
Herreros, E;
Sanz, LM;
Gamo, FJ;
Bathurst, I;
Burrows, JN;
Siegl, P;
Guy, RK;
Winter, RW;
Vaidya, AB;
Charman, SA;
Kyle, DE;
Manetsch, R;
Riscoe, MK;
(2013)
Quinolone-3-diarylethers: a new class of antimalarial drug.
Science translational medicine, 5 (177).
177ra37.
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.3005029
Full text not available from this repository.
O'Neill, PM;
Amewu, RK;
Charman, SA;
Sabbani, S;
Gnädig, NF;
Straimer, J;
Fidock, DA;
Shore, ER;
Roberts, NL;
Wong, MH;
+38 more...
Hong, WD;
Pidathala, C;
Riley, C;
Murphy, B;
Aljayyoussi, G;
Gamo, FJ;
Sanz, L;
Rodrigues, J;
Cortes, CG;
Herreros, E;
Angulo-Barturén, I;
Jiménez-Díaz, MB;
Bazaga, SF;
Martínez-Martínez, MS;
Campo, B;
Sharma, R;
Ryan, E;
Shackleford, DM;
Campbell, S;
Smith, DA;
Wirjanata, G;
Noviyanti, R;
Price, RN;
Marfurt, J;
Palmer, MJ;
Copple, IM;
Mercer, AE;
Ruecker, A;
Delves, MJ;
Sinden, RE;
Siegl, P;
Davies, J;
Rochford, R;
Kocken, CHM;
Zeeman, AM;
Nixon, GL;
Biagini, GA;
Ward, SA;
(2017)
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.
Nature communications, 8.
p. 15159.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms15159
Paquet, T;
Le Manach, C;
Cabrera, DG;
Younis, Y;
Henrich, PP;
Abraham, TS;
Lee, MCS;
Basak, R;
Ghidelli-Disse, S;
Lafuente-Monasterio, MJ;
+43 more...
Bantscheff, M;
Ruecker, A;
Blagborough, AM;
Zakutansky, SE;
Zeeman, AM;
White, KL;
Shackleford, DM;
Mannila, J;
Morizzi, J;
Scheurer, C;
Angulo-Barturen, I;
Martínez, MS;
Ferrer, S;
Sanz, LM;
Gamo, FJ;
Reader, J;
Botha, M;
Dechering, KJ;
Sauerwein, RW;
Tungtaeng, A;
Vanachayangkul, P;
Lim, CS;
Burrows, J;
Witty, MJ;
Marsh, KC;
Bodenreider, C;
Rochford, R;
Solapure, SM;
Jiménez-Díaz, MB;
Wittlin, S;
Charman, SA;
Donini, C;
Campo, B;
Birkholtz, LM;
Hanson, KK;
Drewes, G;
Kocken, CHM;
Delves, MJ;
Leroy, D;
Fidock, DA;
Waterson, D;
Street, LJ;
Chibale, K;
(2016)
Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase.
Science translational medicine, 9 (387).
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.aad9735
Full text not available from this repository.
Pastrana-Mena, R;
Mathias, DK;
Delves, M;
Rajaram, K;
King, JG;
Yee, R;
Trucchi, B;
Verotta, L;
Dinglasan, RR;
(2016)
A Malaria Transmission-Blocking (+)-Usnic Acid Derivative Prevents Plasmodium Zygote-to-Ookinete Maturation in the Mosquito Midgut.
ACS chemical biology, 11 (12).
pp. 3461-3472.
ISSN 1554-8929
DOI: https://doi.org/10.1021/acschembio.6b00902
Full text not available from this repository.
Phillips, MA;
Lotharius, J;
Marsh, K;
White, J;
Dayan, A;
White, KL;
Njoroge, JW;
El Mazouni, F;
Lao, Y;
Kokkonda, S;
+43 more...
Tomchick, DR;
Deng, X;
Laird, T;
Bhatia, SN;
March, S;
Ng, CL;
Fidock, DA;
Wittlin, S;
Lafuente-Monasterio, M;
Benito, FJ;
Alonso, LM;
Martinez, MS;
Jimenez-Diaz, MB;
Bazaga, SF;
Angulo-Barturen, I;
Haselden, JN;
Louttit, J;
Cui, Y;
Sridhar, A;
Zeeman, AM;
Kocken, C;
Sauerwein, R;
Dechering, K;
Avery, VM;
Duffy, S;
Delves, M;
Sinden, R;
Ruecker, A;
Wickham, KS;
Rochford, R;
Gahagen, J;
Iyer, L;
Riccio, E;
Mirsalis, J;
Bathhurst, I;
Rueckle, T;
Ding, X;
Campo, B;
Leroy, D;
Rogers, MJ;
Rathod, PK;
Burrows, JN;
Charman, SA;
(2015)
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Science translational medicine, 7 (296).
296ra111.
ISSN 1946-6234
DOI: https://doi.org/10.1126/scitranslmed.aaa6645
Full text not available from this repository.
Ramakrishnan, C;
Delves, MJ;
Lal, K;
Blagborough, AM;
Butcher, G;
Baker, KW;
Sinden, RE;
(2013)
Laboratory maintenance of rodent malaria parasites.
Methods in molecular biology (Clifton, NJ), 923.
pp. 51-72.
ISSN 1064-3745
DOI: https://doi.org/10.1007/978-1-62703-026-7_5
Full text not available from this repository.
Ruecker, A;
Mathias, DK;
Straschil, U;
Churcher, TS;
Dinglasan, RR;
Leroy, D;
Sinden, RE;
Delves, MJ;
(2014)
A male and female gametocyte functional viability assay to identify biologically relevant malaria transmission-blocking drugs.
Antimicrobial agents and chemotherapy, 58 (12).
pp. 7292-302.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.03666-14
Full text not available from this repository.
Sala, KA;
Nishiura, H;
Upton, LM;
Zakutansky, SE;
Delves, MJ;
Iyori, M;
Mizutani, M;
Sinden, RE;
Yoshida, S;
Blagborough, AM;
(2014)
The Plasmodium berghei sexual stage antigen PSOP12 induces anti-malarial transmission blocking immunity both in vivo and in vitro.
Vaccine, 33 (3).
pp. 437-45.
ISSN 0264-410X
DOI: https://doi.org/10.1016/j.vaccine.2014.11.038
Full text not available from this repository.
Sinden, RE;
Blagborough, AM;
Churcher, T;
Ramakrishnan, C;
Biswas, S;
Delves, MJ;
(2012)
The design and interpretation of laboratory assays measuring mosquito transmission of Plasmodium.
Trends in parasitology, 28 (11).
pp. 457-65.
ISSN 1471-4922
DOI: https://doi.org/10.1016/j.pt.2012.07.005
Full text not available from this repository.
Slavic, K;
Delves, MJ;
Prudêncio, M;
Talman, AM;
Straschil, U;
Derbyshire, ET;
Xu, Z;
Sinden, RE;
Mota, MM;
Morin, C;
+3 more...
Tewari, R;
Krishna, S;
Staines, HM;
(2011)
Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle.
Antimicrobial agents and chemotherapy, 55 (6).
pp. 2824-30.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.01739-10
Full text not available from this repository.
Upton, LM;
Brock, PM;
Churcher, TS;
Ghani, AC;
Gething, PW;
Delves, MJ;
Sala, KA;
Leroy, D;
Sinden, RE;
Blagborough, AM;
(2014)
Lead clinical and preclinical antimalarial drugs can significantly reduce sporozoite transmission to vertebrate populations.
Antimicrobial agents and chemotherapy, 59 (1).
pp. 490-7.
ISSN 0066-4804
DOI: https://doi.org/10.1128/AAC.03942-14
Full text not available from this repository.
Vaidya, AB;
Morrisey, JM;
Zhang, Z;
Das, S;
Daly, TM;
Otto, TD;
Spillman, NJ;
Wyvratt, M;
Siegl, P;
Marfurt, J;
+21 more...
Wirjanata, G;
Sebayang, BF;
Price, RN;
Chatterjee, A;
Nagle, A;
Stasiak, M;
Charman, SA;
Angulo-Barturen, I;
Ferrer, S;
Belén Jiménez-Díaz, M;
Martínez, MS;
Gamo, FJ;
Avery, VM;
Ruecker, A;
Delves, M;
Kirk, K;
Berriman, M;
Kortagere, S;
Burrows, J;
Fan, E;
Bergman, LW;
(2014)
Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.
Nature communications, 5.
p. 5521.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms6521
Vanaerschot, M;
Lucantoni, L;
Li, T;
Combrinck, JM;
Ruecker, A;
Kumar, TRS;
Rubiano, K;
Ferreira, PE;
Siciliano, G;
Gulati, S;
+16 more...
Henrich, PP;
Ng, CL;
Murithi, JM;
Corey, VC;
Duffy, S;
Lieberman, OJ;
Veiga, MI;
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