Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles.

Ellis, Gemma L; Amewu, Richard; Sabbani, Sunil; Stocks, Paul A; Shone, Alison; Stanford, Deborah; Gibbons, Peter; Davies, Jill; Vivas, Livia; Charnaud, Sarah; +8 more... Bongard, Emily; Hall, Charlotte; Rimmer, Karen; Lozanom, Sonia; Jesús, María; Gargallo, Domingo; Ward, Stephen A; O'Neill, Paul M; (2008) Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles. Journal of medicinal chemistry, 51 (7). pp. 2170-2177. ISSN 0022-2623 DOI: https://doi.org/10.1021/jm701435h

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