Comparison of three commercial immunoassays for detection of herpes simplex virus type 2 antibodies in commercial sex workers in Yunnan Province, China.
Ngo, Thoai D;
Laeyendecker, Oliver;
Morrow, Rhoda Ashley;
Lai, Shenghan;
Quinn, Thomas C;
(2008)
Comparison of three commercial immunoassays for detection of herpes simplex virus type 2 antibodies in commercial sex workers in Yunnan Province, China.
Clinical and vaccine immunology, 15 (8).
pp. 1301-1303.
ISSN 1556-6811
DOI: https://doi.org/10.1128/CVI.00006-08
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Five hundred commercial sex workers in China were tested for herpes simplex virus type 2 by three immunoassays and Western blotting. Sensitivities for the Focus, Kalon, and Biokit assays were 86.7%, 82.3%, and 34.9%, respectively, and specificities were 91.8%, 94.2%, and 60.1%, respectively. The Focus assay performed optimally at an index of 1.5 (95.2% sensitivity and 93.4% specificity), and the Kalon assay performed optimally at an index of 1.2 (93.3% sensitivity and 95.2% specificity).
