Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model.

Justin Dixon ORCID logo ; Ben Morton ; Misheck J Nkhata ORCID logo ; Alan Silman ; Ibrahim G Simiyu ; Stephen A Spencer ORCID logo ; Myrna Van Pinxteren ; Christopher Bunn ORCID logo ; Claire Calderwood ORCID logo ; Clare IR Chandler ORCID logo ; +52 more... Edith Chikumbu ORCID logo ; Amelia C Crampin ORCID logo ; John R Hurst ORCID logo ; Modou Jobe ORCID logo ; Andre Pascal Kengne ; Naomi S Levitt ; Mosa Moshabela ; Mayowa Owolabi ; Nasheeta Peer ORCID logo ; Nozgechi Phiri ORCID logo ; Sally J Singh ; Tsaone Tamuhla ; Mandikudza Tembo ; Nicki Tiffin ; Eve Worrall ORCID logo ; Nateiya M Yongolo ; Gift T Banda ; Fanuel Bickton ORCID logo ; Abbi-Monique Mamani Bilungula ORCID logo ; Edna Bosire ; Marlen S Chawani ; Beatrice Chinoko ; Mphatso Chisala ; Jonathan Chiwanda ; Sarah Drew ; Lindsay Farrant ; Rashida A Ferrand ORCID logo ; Mtisunge Gondwe ; Celia L Gregson ORCID logo ; Richard Harding ; Dan Kajungu ; Stephen Kasenda ORCID logo ; Winceslaus Katagira ORCID logo ; Duncan Kwaitana ORCID logo ; Emily Mendenhall ORCID logo ; Adwoa Bemah Boamah Mensah ; Modai Mnenula ; Lovemore Mupaza ; Maud Mwakasungula ; Wisdom Nakanga ; Chiratidzo Ndhlovu ORCID logo ; Kennedy Nkhoma ; Owen Nkoka ORCID logo ; Edwina Addo Opare-Lokko ORCID logo ; Jacob Phulusa ; Alison Price ORCID logo ; Jamie Rylance ; Charity Salima ; Sangwani Salimu ; Joachim Sturmberg ORCID logo ; Elizabeth Vale ; Felix Limbani ; (2024) Interdisciplinary perspectives on multimorbidity in Africa: Developing an expanded conceptual model. PLOS global public health, 4 (7). e0003434-. ISSN 2767-3375 DOI: 10.1371/journal.pgph.0003434
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Multimorbidity is an emerging challenge for health systems globally. It is commonly defined as the co-occurrence of two or more chronic conditions in one person, but its meaning remains a lively area of academic debate, and the utility of the concept beyond high-income settings is uncertain. This article presents the findings from an interdisciplinary research initiative that drew together 60 academic and applied partners working in 10 African countries to answer the questions: how useful is the concept of multimorbidity within Africa? Can the concept be adapted to context to optimise its transformative potentials? During a three-day concept-building workshop, we investigated how the definition of multimorbidity was understood across diverse disciplinary and regional perspectives, evaluated the utility and limitations of existing concepts and definitions, and considered how to build a more context-sensitive, cross-cutting description of multimorbidity. This iterative process was guided by the principles of grounded theory and involved focus- and whole-group discussions during the workshop, thematic coding of workshop discussions, and further post-workshop development and refinement. Three thematic domains emerged from workshop discussions: the current focus of multimorbidity on constituent diseases; the potential for revised concepts to centre the priorities, needs, and social context of people living with multimorbidity (PLWMM); and the need for revised concepts to respond to varied conceptual priorities amongst stakeholders. These themes fed into the development of an expanded conceptual model that centres the catastrophic impacts multimorbidity can have for PLWMM, families and support structures, service providers, and health systems.


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