Tranexamic acid for the prevention of postpartum hemorrhage in women undergoing cesarean delivery.

Sentilhes, Loïc; Deneux-Tharaux, Catherine; Roberts, Ian; Ker, Katharine; (2022) Tranexamic acid for the prevention of postpartum hemorrhage in women undergoing cesarean delivery. American journal of obstetrics and gynecology, 226 (5). pp. 755-756. ISSN 0002-9378 DOI: https://doi.org/10.1016/j.ajog.2021.12.039

Abstract

We read with interest the meta-analysis performed by Bellos and Pergialotis.1 The authors included 36 randomized controlled trials involving 10,659 women. The authors judged that none of the included trials were at a high risk of bias, with 21 (58.3%) trials judged to be at a low risk and 15 (41.7%) trials to be at a moderate risk of bias; the remainder were rated as unclear. The fact that no trials were judged to be at a high risk of bias was included as a strength of the meta-analysis and apparently informed the conclusions. We, however, strongly disagree.

Additional Information

Item Type	Article
Faculty and Department	Faculty of Epidemiology and Population Health > Dept of Medical Statistics
Research Centre	Clinical Trials Unit
PubMed ID	34968456
Elements ID	169552
Official URL	http://dx.doi.org/10.1016/j.ajog.2021.12.039

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Filename: Ker-etal-2023-Letter-Tranexamic-acid-for-the-prevention-of-postpartum-hemorrhage-in-women-undergoing-cesarean-delivery.pdf

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