Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States.

Cramer, Estee YORCID logo; Ray, Evan LORCID logo; Lopez, Velma KORCID logo; Bracher, JohannesORCID logo; Brennen, Andrea; Castro Rivadeneira, Alvaro J; Gerding, Aaron; Gneiting, TilmannORCID logo; House, Katie H; Huang, Yuxin; +285 more...Jayawardena, Dasuni; Kanji, Abdul H; Khandelwal, Ayush; Le, Khoa; Mühlemann, Anja; Niemi, JaradORCID logo; Shah, Apurv; Stark, Ariane; Wang, Yijin; Wattanachit, Nutcha; Zorn, Martha W; Gu, Youyang; Jain, Sansiddh; Bannur, Nayana; Deva, Ayush; Kulkarni, Mihir; Merugu, Srujana; Raval, Alpan; Shingi, Siddhant; Tiwari, Avtansh; White, JeromeORCID logo; Abernethy, Neil F; Woody, SpencerORCID logo; Dahan, Maytal; Fox, SpencerORCID logo; Gaither, KellyORCID logo; Lachmann, Michael; Meyers, Lauren AncelORCID logo; Scott, James G; Tec, MauricioORCID logo; Srivastava, Ajitesh; George, Glover EORCID logo; Cegan, Jeffrey CORCID logo; Dettwiller, Ian D; England, William P; Farthing, Matthew W; Hunter, Robert HORCID logo; Lafferty, BrandonORCID logo; Linkov, Igor; Mayo, Michael LORCID logo; Parno, Matthew D; Rowland, Michael AORCID logo; Trump, Benjamin D; Zhang-James, Yanli; Chen, SamuelORCID logo; Faraone, Stephen V; Hess, Jonathan; Morley, Christopher P; Salekin, AsifORCID logo; Wang, Dongliang; Corsetti, Sabrina MORCID logo; Baer, Thomas M; Eisenberg, Marisa C; Falb, KarlORCID logo; Huang, YitaoORCID logo; Martin, Emily T; McCauley, Ella; Myers, Robert L; Schwarz, Tom; Sheldon, DanielORCID logo; Gibson, Graham Casey; Yu, Rose; Gao, Liyao; Ma, Yian; Wu, Dongxia; Yan, Xifeng; Jin, Xiaoyong; Wang, Yu-Xiang; Chen, YangQuan; Guo, LihongORCID logo; Zhao, Yanting; Gu, QuanquanORCID logo; Chen, Jinghui; Wang, Lingxiao; Xu, PanORCID logo; Zhang, Weitong; Zou, Difan; Biegel, Hannah; Lega, JocelineORCID logo; McConnell, SteveORCID logo; Nagraj, VP; Guertin, Stephanie L; Hulme-Lowe, Christopher; Turner, Stephen DORCID logo; Shi, YunfengORCID logo; Ban, Xuegang; Walraven, RobertORCID logo; Hong, Qi-Jun; Kong, Stanley; van de Walle, AxelORCID logo; Turtle, James AORCID logo; Ben-Nun, MichalORCID logo; Riley, StevenORCID logo; Riley, Pete; Koyluoglu, UgurORCID logo; DesRoches, David; Forli, Pedro; Hamory, Bruce; Kyriakides, Christina; Leis, Helen; Milliken, John; Moloney, Michael; Morgan, James; Nirgudkar, Ninad; Ozcan, Gokce; Piwonka, Noah; Ravi, Matt; Schrader, Chris; Shakhnovich, Elizabeth; Siegel, Daniel; Spatz, Ryan; Stiefeling, Chris; Wilkinson, Barrie; Wong, Alexander; Cavany, SeanORCID logo; España, GuidoORCID logo; Moore, SeanORCID logo; Oidtman, RachelORCID logo; Perkins, AlexORCID logo; Kraus, DavidORCID logo; Kraus, Andrea; Gao, Zhifeng; Bian, Jiang; Cao, WeiORCID logo; Lavista Ferres, JuanORCID logo; Li, Chaozhuo; Liu, Tie-Yan; Xie, Xing; Zhang, Shun; Zheng, Shun; Vespignani, AlessandroORCID logo; Chinazzi, Matteo; Davis, Jessica T; Mu, Kunpeng; Pastore Y Piontti, Ana; Xiong, Xinyue; Zheng, Andrew; Baek, Jackie; Farias, Vivek; Georgescu, Andreea; Levi, Retsef; Sinha, DeekshaORCID logo; Wilde, Joshua; Perakis, GeorgiaORCID logo; Bennouna, Mohammed AmineORCID logo; Nze-Ndong, David; Singhvi, Divya; Spantidakis, IoannisORCID logo; Thayaparan, Leann; Tsiourvas, AsteriosORCID logo; Sarker, ArnabORCID logo; Jadbabaie, AliORCID logo; Shah, DevavratORCID logo; Della Penna, Nicolas; Celi, Leo AORCID logo; Sundar, Saketh; Wolfinger, Russ; Osthus, DaveORCID logo; Castro, Lauren; Fairchild, GeoffreyORCID logo; Michaud, Isaac; Karlen, Dean; Kinsey, Matt; Mullany, Luke CORCID logo; Rainwater-Lovett, KaitlinORCID logo; Shin, Lauren; Tallaksen, Katharine; Wilson, Shelby; Lee, Elizabeth CORCID logo; Dent, JuanORCID logo; Grantz, Kyra H; Hill, Alison LORCID logo; Kaminsky, Joshua; Kaminsky, Kathryn; Keegan, Lindsay TORCID logo; Lauer, Stephen A; Lemaitre, Joseph CORCID logo; Lessler, Justin; Meredith, Hannah R; Perez-Saez, Javier; Shah, Sam; Smith, Claire P; Truelove, Shaun AORCID logo; Wills, JoshORCID logo; Marshall, Maximilian; Gardner, Lauren; Nixon, Kristen; Burant, John C; Wang, Lily; Gao, LeiORCID logo; Gu, ZhilingORCID logo; Kim, Myungjin; Li, Xinyi; Wang, Guannan; Wang, Yueying; Yu, ShanORCID logo; Reiner, Robert C; Barber, Ryan; Gakidou, Emmanuela; Hay, Simon IORCID logo; Lim, Steve; Murray, ChrisORCID logo; Pigott, David; Gurung, Heidi L; Baccam, Prasith; Stage, Steven AORCID logo; Suchoski, Bradley T; Prakash, B AdityaORCID logo; Adhikari, Bijaya; Cui, Jiaming; Rodríguez, AlexanderORCID logo; Tabassum, Anika; Xie, JiajiaORCID logo; Keskinocak, PinarORCID logo; Asplund, John; Baxter, ArdenORCID logo; Oruc, Buse EylulORCID logo; Serban, Nicoleta; Arik, Sercan O; Dusenberry, Mike; Epshteyn, Arkady; Kanal, Elli; Le, Long T; Li, Chun-Liang; Pfister, Tomas; Sava, Dario; Sinha, RajarishiORCID logo; Tsai, Thomas; Yoder, NateORCID logo; Yoon, Jinsung; Zhang, LeyouORCID logo; Abbott, Sam; Bosse, Nikos I; Funk, SebastianORCID logo; Hellewell, Joel; Meakin, Sophie RORCID logo; Sherratt, KatharineORCID logo; Zhou, Mingyuan; Kalantari, Rahi; Yamana, Teresa KORCID logo; Pei, SenORCID logo; Shaman, JeffreyORCID logo; Li, Michael LORCID logo; Bertsimas, DimitrisORCID logo; Skali Lami, OmarORCID logo; Soni, SakshamORCID logo; Tazi Bouardi, HamzaORCID logo; Ayer, Turgay; Adee, Madeline; Chhatwal, Jagpreet; Dalgic, Ozden O; Ladd, Mary A; Linas, Benjamin P; Mueller, Peter; Xiao, Jade; Wang, YuanjiaORCID logo; Wang, Qinxia; Xie, Shanghong; Zeng, Donglin; Green, Alden; Bien, Jacob; Brooks, Logan; Hu, Addison J; Jahja, Maria; McDonald, DanielORCID logo; Narasimhan, Balasubramanian; Politsch, CollinORCID logo; Rajanala, SamyakORCID logo; Rumack, AaronORCID logo; Simon, Noah; Tibshirani, Ryan JORCID logo; Tibshirani, Rob; Ventura, Valerie; Wasserman, Larry; O'Dea, Eamon B; Drake, John MORCID logo; Pagano, Robert; Tran, Quoc T; Ho, Lam Si TungORCID logo; Huynh, Huong; Walker, Jo W; Slayton, Rachel BORCID logo; Johansson, Michael AORCID logo; Biggerstaff, MatthewORCID logo; and Reich, Nicholas GORCID logo (2022) Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States. Proceedings of the National Academy of Sciences, 119 (15). e2113561119-. ISSN 0027-8424 DOI: 10.1073/pnas.2113561119
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Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks.


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