Antibiotic Practices, Perceptions and Self-Medication Among Patients at a National Referral Hospital in Uganda.

Nabaweesi, Irene; Olum, Ronald; Sekite, Arthur Brian; Suubi, Willy Tumwesigye; Nakiwunga, Prossy; Machali, Aron; Kiyumba, Richard; Kalyango, Peter; Natamba, Allen; Igumba, Yokosofati; +3 more... Kyeyune, Martin; Mpairwe, Harriet; Katagirya, Eric; (2021) Antibiotic Practices, Perceptions and Self-Medication Among Patients at a National Referral Hospital in Uganda. Infection and drug resistance, 14. pp. 2155-2164. ISSN 1178-6973 DOI: https://doi.org/10.2147/IDR.S303075

Abstract

BACKGROUND: Antimicrobial resistance (AMR) is a major global health concern with increasing reports of microorganisms resistant to most of the available antibiotics. There are limited data on antibiotic practices, perceptions and self-medication among Ugandans, necessitating this study. METHODS: A cross-sectional study was conducted among patients at Kiruddu National Referral Hospital, Kampala, Uganda. A pre-tested interviewer administered a questionnaire that was used to collect data after an informed consent. Chi-square tests and logistic regression were used to assess associations between outcome and exposure variables. A P<0.05 was statistically significant. RESULTS: A total of 279 patients (response rate=71%) with a median age of 32 years participated in the study. The majority were females (55.6%, n=155) and from the outpatient department (74.9%, n=209). Overall, 212 (76%) participants had taken an antibiotic in the past 6 months, and some 22.2% (n=47) of the participants had practiced self-medication. Male participants (adjusted odds ratio (aOR)=2.13, 95% confidence intervals (CI): 1.01 to 4.50, P=0.046) and Muslims (aOR=4.37, 96% CI:1.54 to 12.44, P=0.006) were more likely to self-medicate. Employees (aOR=0.06, 95% CI:0.01 to 0.51, P=0.010) and patients with tertiary education (aOR=0.14, 95% CI: 0.02 to 0.81, P=0.028) were less likely to practice self-medication. About 33% (n=70) of the participants had not completed treatment dosage during their last course of antibiotic treatment because of feeling better (60%, n=42), lack of money to purchase the medication (15.7%, n=11) and side effects (10%, n=7). Whereas 169 participants (79.7%) believed that not completing treatment would have an impact on their personal health, only 96 participants (45.3%) believed that this behaviour could affect the health of others. CONCLUSION: Antibiotic misuse is significant among patients in Uganda. Continuous health education programs aimed at informing the public on antimicrobial resistance, and its dangers are recommended to curtail this challenge.