Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
Hawkey, Charlotte R;
Yap, Timothy;
Pereira, Janis;
Moore, David AJ;
Davidson, Robert N;
Pasvol, Geoffrey;
Kon, Onn Min;
Wall, Robert A;
Wilkinson, Robert J;
(2005)
Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis.
Clinical infectious diseases, 40 (9).
pp. 1368-1371.
ISSN 1058-4838
DOI: https://doi.org/10.1086/429317
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In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus-uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21-139 days) and persisting for a median of 67.5 days (interquartile range, 34-111 days). We found no association between the use of steroids and the duration of reaction.
