T cell protective immune responses against TB

T cell immunity to MTB is both straightforward and incredibly complex. Th is chapter will focus on results obtained from studies of human T cells, but draw on studies in murine models where appropriate. It will provide a brief overview of the main roles played by T cells in immunity to MTB, highlight some areas of recent research, discuss some of the ways in which T cell immune responses can be measured in vaccine trials, and identify areas where further research is needed.