CATH: comprehensive structural and functional annotations for genome sequences.

Sillitoe, Ian; Lewis, Tony E; Cuff, Alison; Das, Sayoni; Ashford, Paul; Dawson, Natalie L; Furnham, Nicholas; Laskowski, Roman A; Lee, David; Lees, Jonathan G; +4 more... Lehtinen, Sonja; Studer, Romain A; Thornton, Janet; Orengo, Christine A; (2014) CATH: comprehensive structural and functional annotations for genome sequences. Nucleic acids research, 43 (Databa). D376-D381. ISSN 0305-1048 DOI: https://doi.org/10.1093/nar/gku947

Abstract

The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235,000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our 'current' putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages.

Additional Information

Item Type	Article
Faculty and Department	Faculty of Infectious and Tropical Diseases > Department of Infection Biology
PubMed ID	25348408
ISI	350210400058
Related URLs	OA Location