In-house phage amplification assay is a sound alternative for detecting rifampin-resistant Mycobacterium tuberculosis in low-resource settings.
Símboli, Norberto; Takiff, Howard; McNerney, Ruth; López, Beatriz; Martin, Anandi; Palomino, Juan Carlos; Barrera, Lucía; and Ritacco, Viviana
(2005)
In-house phage amplification assay is a sound alternative for detecting rifampin-resistant Mycobacterium tuberculosis in low-resource settings.
Antimicrobial agents and chemotherapy, 49 (1).
pp. 425-427.
ISSN 0066-4804
DOI: 10.1128/AAC.49.1.425-427.2005
An in-house mycobacteriophage amplification assay for detecting rifampin-resistant Mycobacterium tuberculosis showed 100% sensitivity, 97.7% specificity, and 95.2% predictive value for resistance in a test of 129 isolates from a hot spot area of multidrug-resistant M. tuberculosis. The applicability of the test was demonstrated in the routine work flow of a low-resource reference laboratory.
| Item Type | Article |
|---|---|
| ISI | 226035300057 |
| Date Deposited | 17 Oct 2011 20:22 |
Explore Further
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538913 (OA Location)
- 10.1128/AAC.49.1.425-427.2005 (DOI)
- 15616326 (PubMed)